Search Results (7,204)

As the core component of electrified railway power supply systems, the fatigue performance and reliability of catenary support structures are directly related to the operational safety of high-speed railways. To address the problem of structural fatigue damage caused by increasing train speed and high-frequency operation, this study develops a refined finite element model including a support structure, suspension system and support column, and the dynamic response characteristics and fatigue life evolution law under train operation conditions are systematically analyzed. The results show that under the conditions of 250 km/h speed and 100 times daily traffic, the fatigue lives of the limit locator and positioning support are 43.56 years and 34.48 years, respectively, whereas the transverse cantilever connection and inclined cantilever have infinite life characteristics. When the train speed increases to 400 km/h, the annual fatigue damage of the positioning bearing increases from 0.029 to 0.065, and the service life is shortened by 55.7% to 15.27 years, which proves that high-speed working conditions significantly aggravate the deterioration of fatigue in the structure. The reliability analysis based on Monte Carlo simulation reveals that when the speed is 400 km/h and the daily traffic is 130 times, the structural reliability shows an exponential declining trend with increasing service life. If the daily traffic frequency exceeds 130, the 15-year reliability decreases to 92.5%, the 20-year reliability suddenly decreases to 82.4%, and there is a significant inflection point of failure in the 15–20 years of service. Considering the coupling effect of environmental factors (wind load, temperature and freezing), the actual failure risk may be higher than the theoretical value. On the basis of these findings, engineering suggestions are proposed: for high-speed lines with a daily traffic frequency of more than 130 times, shortening the overhaul cycle of the catenary support structure to 7–10 years and strengthening the periodic inspection and maintenance of positioning support and limit locators are recommended. The research results provide a theoretical basis for the safety assessment and maintenance decision making of high-speed railway catenary systems. Full article

This paper reviews the current research landscape on Personal Saving Behavior, focusing on its antecedents and outcomes. Using bibliographic analysis of publication trends—highlighting productive authors, journals, countries, and keywords—the literature is synthesized. A framework-based systematic review is conducted to understand factors influencing saving behavior and its effects, employing the TCM framework to analyze theory, context, and methods across selected studies. Additionally, the ADO framework is used to discuss antecedents, decisions, and outcomes related to personal saving behavior. The review consolidates 112 articles from 2000 to 2025, grouping unique antecedents into nine categories. It also examines how specific antecedents positively or negatively impact saving decisions and outcomes. Finally, using the TCM and ADO frameworks, the study identifies research gaps and discusses future directions, especially from the perspectives of behavioral economics and critical incidents. Full article

There are close relationships between vertical positions in space and auditory experiences of fundamental frequency (F0), which even very young children seem to use. Like adults, they associate higher or rising F0 values with upper positions in space and vice versa for lower or falling F0 values. Here, we tested whether caregivers’ speech capitalizes on these associations to guide the attention of very young children (18 to 24 months). Together with their child, caregivers saw four different objects (in the corners of a computer screen). Caregivers produced standardized sentences (e.g., “Look at the hat.”). We observed a significantly increased maximum F0 (but no differences in mean or minimum F0) at the onset of the utterance when the to be named object appeared at an upper position compared to the same object at a lower position. Furthermore, exploratory analyses of F0 dynamics of caregivers’ utterances indicated that the higher F0 maximum was part of a more prominent F0 increase for objects appearing at an upper compared to a lower position. Adults without a child present and less experience in interacting with children did not show systematic pitch modulation when addressing an imagined child in the same study set-up. Thus, caregivers appear to systematically modulate F0 dynamics to provide an effective language environment when they are interacting with their child. Full article

Biofilm formation is a key factor in microbial survival and persistence, often contributing to reduced antimicrobial susceptibility. This systematic literature review investigates whether increased biofilm formation correlates with decreased antibiotic susceptibility. The literature search was conducted in the Pubmed database and we identified and screened 328 studies, with 35 ultimately meeting the inclusion criteria for detailed analysis. Findings reveal that the relationship between biofilm size and antimicrobial susceptibility is highly variable and influenced by multiple factors, including microbial species, strain-specific traits, antibiotic type, and experimental methodologies. While some studies report a positive correlation between biofilm biomass and reduced susceptibility, others show weak or no such relationships, and statistical support for a correlation is often lacking (also due to small sample sizes). The lack of standardized biofilm quantification methods and susceptibility metrics further complicates cross-study comparisons. These findings underscore the need for standardized protocols and more comprehensive datasets to clarify the complex interplay between biofilm formation and antibiotic susceptibility. Regardless of these difficulties, the available data clearly indicate that ‘bigger’ biofilms are not by definition less susceptible. Future research should prioritize diverse and sufficiently large strain collections and consistent methodologies to better understand and address biofilm-associated antimicrobial tolerance. Full article

Background: attention-deficit/hyperactivity disorder (ADHD) and Alzheimer’s disease (AD) are distinct neurological conditions that may share genetic and molecular underpinnings. ADHD, a neurodevelopmental disorder, affects approximately 5% of children and 3% of adults globally, while AD, a neurodegenerative disorder, is the leading cause of dementia in older adults. Emerging evidence suggests potential overlapping contributors, including pathways related to synaptic plasticity, neuroinflammation, and oxidative stress. Methods: this systematic review investigated potential genetic predispositions linking Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer’s Disease (AD). Following PRISMA guidelines, a search was conducted in Web of Science, Embase, PsycINFO, and PubMed using keywords related to ADHD, AD, and genetic factors. Studies included were original human studies utilizing genetic analyses and ADHD polygenic risk scores (PRS), with AD confirmed using established diagnostic criteria. Exclusion criteria comprised non-original studies, animal research, and articles not addressing genetic links between ADHD and AD. Screening was conducted with Rayyan software, assessing relevance based on titles, abstracts, and full texts. Results:. The search identified 1450 records, of which 1092 were screened after duplicates were removed. Following exclusions, two studies met inclusion criteria. One study analyzed ADHD-PRS in 212 cognitively unimpaired older adults using amyloid-beta (Aβ) PET imaging and tau biomarkers. The findings revealed that ADHD-PRS was associated with progressive cognitive decline, increased tau pathology, and frontoparietal atrophy in Aβ-positive individuals, suggesting that ADHD genetic liability may exacerbate AD pathology. Another study assessed ADHD-PRS in a cohort of 10,645 Swedish twins, examining its association with 16 somatic conditions. The results showed modest risk increases for cardiometabolic, autoimmune, and neurological conditions, with mediation effects through BMI, education, tobacco use, and alcohol misuse, but no direct link between ADHD-PRS and dementia. Discussion and conclusion: this review highlights preliminary but conflicting evidence for a genetic intersection between ADHD and AD. One study suggests that ADHD genetic liability may exacerbate AD-related pathology in Aβ-positive individuals, whereas another large registry-based study finds no direct link to dementia, with associations largely mediated by lifestyle factors. The potential ADHD–AD relationship is likely complex and context-dependent, influenced by biomarker status and environmental confounders. Longitudinal studies integrating genetics, biomarkers, and detailed lifestyle data are needed to clarify this relationship. Full article

Background and Objectives: Children with autism spectrum disorder (ASD) often experience visual problems, yet their ophthalmic health remains underexplored due to testability challenges and limited-service access. This study evaluated ophthalmic screening outcomes in children with ASD and examined whether autism severity influenced ocular findings or cooperation during examinations. Materials and Methods: This cross-sectional study included 210 children with ASD (mean age 8.18 ± 4.99 years; 83.3% male). Examinations were conducted in an autism education center using non-contact methods: stereopsis (LANG I stereotest; LANG-STEREOTEST AG, Küsnacht, Switzerland), cover–uncover, and Hirschberg tests for strabismus, Spot Vision Screener (Welch Allyn Inc., Skaneateles Falls, NY, USA) for refractive errors, and Brückner test for red reflex. Autism severity was assessed with the Turkish version of the Adapted Autism Behavior Checklist (AABC). Results: Refractive errors were identified in 22.3% of participants: astigmatism in 15.2%, myopia in 5.2% (including 3 high myopia), and hyperopia in 1.9%. Strabismus was present in 11.9%, most commonly intermittent exotropia. Nearly half (49.5%) could not complete stereopsis testing, and a weak positive correlation was observed between AABC scores and the higher absolute spherical equivalent (SE) value between the two eyes (r = 0.173, p = 0.044). Children unable to complete stereopsis testing had significantly higher AABC scores (22.66 ± 9.69 vs. 13.39 ± 9.41, p < 0.001). Notably, 50 children (23.8%) had never undergone an eye examination prior to this study. Conclusions: Ophthalmic findings, particularly astigmatism and strabismus, are common in children with ASD. Greater autism severity was associated with reduced testability and modestly worse refractive error status. These findings suggest that tailored, accessible eye-care approaches and systematic vision screening may help to reduce overlooked visual problems and support more equitable care for children with ASD. Full article

To explore strategies for the safe utilization of farmland co-contaminated with cadmium (Cd) and lead (Pb), this field study systematically evaluated the impacts of humic acid (HA) and potassium fulvate (PF) at different application rates (0, 1500, 3000, and 4500 kg·ha⁻¹) on the growth, yield, and translocation of Cd and Pb within the soil–plant system of maize (Zea mays L.). The results showed that while HA and PF did not significantly alter total soil Cd and Pb concentrations, they markedly reduced their bioavailable fractions. This mitigation of heavy metal phytotoxicity significantly promoted maize growth and yield, with the high-dose HA treatment increasing yield by a maximum of 32.9%. Both amendments dose-dependently decreased Cd and Pb concentrations, bioconcentration factors (BCF), and translocation factors (TF) in all maize tissues, particularly in the grains. At equivalent application rates, PF was slightly more effective than HA in reducing heavy metal concentrations in the grains. Notably, a significant positive correlation was observed between Cd and Pb concentrations across all plant parts, confirming a synergistic accumulation and translocation mechanism. This synergy provides a physiological explanation for the broad-spectrum immobilization efficacy of these humic substances. In conclusion, applying HA and PF presents a dual-benefit strategy for increasing yield and reducing risks in Cd- and Pb-contaminated farmlands. This study proposes a differentiated application approach: PF is the preferred option when ensuring food-grade safety is the primary goal, whereas high-dose HA is more advantageous for maximizing yield in soils with low-to-moderate contamination risk. Full article

We explore a plasmonic interface for perovskite solar cells (PSCs) by integrating inkjet-printed TiO₂-AuNP microdot arrays (MDA) into the electron transport layer. This systematic study examines how the TiO₂ blocking layer (BL) surface conditioning, AuNP layer positioning, and nanoparticle loading collectively influence device performance. Pre-annealing the BL increases its hydrophobicity, yielding smaller and denser AuNP microdots with an enhanced localized surface plasmon resonance (LSPR). Positioning the AuNP MDA at the BL/perovskite interface (above the BL) maximizes near-field plasmonic coupling to the absorber, resulting in higher photocurrent and power conversion devices; these trends are corroborated by finite-difference time-domain (FDTD) simulations. Moreover, these devices demonstrate better stability over time compared to those with AuNPs at the transparent electrode (under BL). Although higher AuNP concentrations improve dispersion stability, preserve MAPI crystallinity, and yield more uniform nanoparticle sizes, device measurements showed no performance gains. After annealing, the samples with the Au content of 23 wt% relative to TiO₂ achieved optimal PSC efficiency by balancing plasmonic enhancement and charge transport without the increased resistance and recombination losses seen at higher loadings. Importantly, X-ray diffraction (XRD) confirms that introducing the TiO₂-AuNP MDA at the interface does not disrupt the perovskite’s crystal structure, underscoring the structural compatibility of this plasmonic enhancement. Overall, our findings highlight a scalable strategy to boost PSC efficiency via engineered light-matter interactions at the nanoscale without compromising the perovskite’s structural integrity. Full article

Background/Objectives: Soft tissue sarcomas (STS) of the hand are rare, representing only 2% of all STS. The small size and benign appearance of these tumors often lead to unplanned excisions and diagnostic delay. This systematic review sought to characterize the clinical presentation, histology, treatment modalities, and oncological outcomes of hand STS. Methods: A systematic review of PubMed and Embase was conducted following PRISMA guidelines. The protocol was registered on PROSPERO. We included studies with ≥10 patients with STS that provided data on treatment options and oncologic outcomes. Data was extracted regarding demographics, tumor features, treatment modalities, and survival metrics. Results: Eighteen studies comprising 570 patients were included. Most tumors were <5 cm, and 56.8% were deep (subfascial). Epithelioid and synovial sarcomas were the most common histologies, accounting for 27% and 17% of cases, respectively. UEs were seen in 57% of cases, and 26% of patients required amputation. Positive surgical margins were reported in 16% of patients. Radiation therapy and chemotherapy were used in 40% and 17% of patients, respectively. Twelve and 15% of patients developed regional lymph node and distant metastases, respectively. Local recurrence occurred in 20% of cases. Five- and ten-year overall survival were 80% and 77%, respectively. Disease-free survival at those time points were 77% and 74%, respectively. Conclusions: Hand STSs are challenging due to their rarity, small size, and high rates of UEs. Despite favorable survival rates, local recurrence and metastases remain a concern. Early referral to specialized centers and individualized treatment strategies are essential for improving outcomes. Full article

Rapid advancements in artificial intelligence and the Internet of Things (IoT) have fueled the growth of furniture, transforming traditional home environments into intelligent living spaces. As consumer adoption accelerates, understanding user concerns and sentiment trends becomes crucial for brands to refine product offerings and enhance market competitiveness. This study systematically investigates consumer concerns and sentiment trends toward furniture products by analyzing user-generated reviews across two major e-commerce platforms: Jingdong and Taobao. Leveraging advanced text-mining methods including TF-IDF keyword extraction, hierarchical clustering, Graph of Words–Latent Dirichlet Allocation (GoW-LDA) topic modeling, and BERT-based sentiment analysis, this research identifies critical user preferences, product satisfaction factors, and platform-specific behavioral patterns. Results reveal distinct cross-platform differences; Jingdong users prioritize service quality, brand trust, and logistical efficiency, whereas Taobao users emphasize product aesthetics, material selection, and cost-effectiveness. The sentiment analysis demonstrates that Jingdong users exhibit more consistent and positive feedback, while sentiment on Taobao displays higher variability due to product-quality discrepancies and price sensitivity. Full article

With the widespread integration of Artificial Intelligence-Generated Content (AIGC) into e-commerce platforms, understanding how users perceive, evaluate, and respond to such content has become a critical issue for both academia and industry. This study examines the influence mechanism of AIGC Content Quality (AIGCQ) on users’ Purchase Intention (PI) by constructing a cognitive model centered on Trust (TR) and Perceived Risk (PR). Additionally, it introduces two moderating variables—Ethical Concern (EC) and Perceived Platform Responsibility (PLR)—to explore higher-order psychological influences. The research variables were identified through a systematic literature review and expert interviews, followed by structural equation modeling based on data collected from 507 e-commerce users. The results indicate that AIGCQ significantly reduces users’ PR and enhances TR, while PR negatively and TR positively influence PI, validating the fundamental dual-pathway structure. However, the moderating effects reveal unexpected complexities: PLR simultaneously amplifies both the negative effect of PR and the positive effect of TR on PI, presenting a “dual amplification” pattern; meanwhile, EC weakens the strength of both pathways, manifesting a “dual attenuation” effect. These findings highlight the nonlinear cognitive mechanisms underlying users’ acceptance of AIGC, suggesting that PLR and EC influence decision-making in more intricate ways than previously anticipated. By uncovering the unanticipated patterns in moderation, this study extends the boundary conditions of the trust–risk theoretical framework within AIGC contexts. In practical terms, it reveals that PLR acts as a “double-edged sword,” providing more nuanced guidance for platform governance of AI-generated content, including responsibility frameworks and ethical labeling strategies. Full article

Background: Chronic disease significantly contributes to global healthcare demands and costs. Despite these chronic illnesses, good health is achievable through public health strategies that enhance control over health determinants. This systematic review investigates how control over health determinants affects the health status of individuals with chronic diseases. Objective: To assess the impact of limited control over health determinants on health status in people with chronic diseases and identify potential clinical applications. Methods: A systematic review was conducted following PRISMA 2020 and COSMOS-E guidelines. Searches across five databases (PubMed, Google Scholar, ScienceDirect, CINAHL, PsycARTICLES) between February and April 2023 identified cohort studies published in the last 10 years. Studies involving individuals aged 16 years and older with at least one chronic disease were included. The Newcastle–Ottawa scale was used to assess study quality. Results: Four cohort studies (n = 576) were included, involving participants with chronic diseases such as COPD, diabetes, and Parkinson’s disease. The methodological quality averaged 6/9. Significant correlations were observed between control over four health determinant domains—social, behavioral, biological, and healthcare system—and declining health outcomes. Common biases included detection and comparability bias. Discussion: The studies had acceptable methodological quality and low external bias risks. However, the meta-analysis was compromised due to the heterogeneity observed in the exposure variables of the included articles. The review emphasizes the importance of integrating control over health determinants into patient care, with healthcare professionals positioned to enhance patient control and improve outcomes. Conclusions: Lack of control over health determinants, particularly in social and behavioral domains, correlates with poorer health outcomes in patients with chronic conditions. Assessing and improve healthcare control could identify high-risk patients and improve their quality of life. Full article

Objective: The insertion of venous catheters into supra-aortic vessels is a standard procedure in the treatment of a large number of diseases. Incorrect placement of venous catheters into and accidental perforation of arterial vessels is a rare but serious complication that can lead to severe bleeding, dissections, and strokes. Materials and Methods: We present a case of iatrogenic malposition of a Broviac catheter into the right vertebral artery and its successful treatment through stenting of the perforation site using a Walrus balloon catheter to achieve a secure treatment position and eventually cover the perforation site. Additionally, we conducted a systematic literature review on endovascular rescue procedures in inadvertent injuries of the supra-aortic arteries related to venous catheter placement. Results: A balloon guide catheter was used to achieve a secure treatment position for the deployment of a stent graft covering the perforation site, ensuring no significant arterial hemorrhage occurred during the removal of the incorrectly placed Broviac catheter. The review of the literature on endovascular rescue procedures for supra-aortic arterial vessel damage caused by venous catheter placement revealed that endovascular treatment has been successful in all reported cases of catheter-related supra-aortic arterial injury. Primary stent graft placement without additional actions was the most common treatment approach. Conclusions: In the treatment of iatrogenic injuries to the supra-aortic vessels, endovascular treatment strategies represent a safe, reliable, and generally recognized option and thus are used much more frequently than surgical procedures. Key point: In rare cases of accidental malposition of venous catheters into supra-aortic arterial vessels, endovascular insertion of a stent graft covering the perforation site using a balloon guide catheter can be a safe treatment option. Full article

To optimize the location optimization of the coalbed methane (CBM) extraction target area in abandoned mines, based on the background of the Songzao mining area in Chongqing, theoretical analysis and numerical simulation research methods were comprehensively used to systematically evaluate the potential of residual CBM resources in the goaf of the Songzao mining area. The stress-fracture evolution law and permeability enhancement characteristics of overlying strata under repeated mining of inclined multi-coal seams were deeply revealed, and the location optimization of the residual CBM extraction borehole target area was carried out. The results show that the amount of CBM resources in Songzao Coal Mine is 5.248 × 10⁷ m³, accounting for 26.57% of the total resources, which is suitable for the extraction of CBM left in goaf. The maximum height of the overburden fracture zone caused by repeated mining of K2b, K1, and K3b coal seams in Songzao Coal Mine is 72.3 m, which is basically consistent with the results of the numerical simulation (69.76 m). The fracture development of overlying strata is in the distribution form of a symmetrical trapezoid and inclined asymmetrical trapezoid, and its development height increases with an increase in coal seam mining times, and finally forms a three-dimensional ‘O’-ring fracture area, which provides a channel and enrichment area for the effective migration of CBM. The significant permeability-increasing zone of overburden rock is stable in the range of 10~40 m above the roof of the K3b coal seam and is nearly trapezoidal. According to the calculation of the height prediction model of the fracture zone in the abandoned goaf, the fracture height of the long-term compaction of the Songzao Coal Mine is reduced to 63.74 m. Based on the stress-fracture evolution characteristics of the overburden rock, combined with the permeability-increasing characteristics of the overburden rock and the migration law of the remaining CBM, it is determined that the preferred position of the remaining CBM extraction target area of the Songzao Coal Mine should be in the upper corner of the fracture development area within the range of 10~32.47 m above the K36 coal seam. Full article

Agricultural soils near industrial parks in the Yellow River bend region face severe heavy metal pollution, posing a significant to human health. This study integrated field sampling with laboratory analysis and applied geostatistical analysis, positive matrix factorization (PMF) modeling, and health risk assessment models to systematically investigate the pollution levels, spatial distribution, sources, and ecological health risks of heavy metals in the area. The main findings are as follows: (1) The average concentrations of the eight heavy metals (Hg, Cr, Cu, Pb, Zn, As, Cd, and Ni) in the study area were 0.04, 48.3, 54.3, 45.7, 70.0, 22.9, 0.4, and 35.7 mg·kg⁻¹, respectively. The concentrations exceeded local background values by factors ranging from 1.32 to 11.2. Exceedances of soil screening and control values were particularly pronounced for Cd and As. Based on the geoaccumulation index, over 75% of the sampling sites for Cr, Pb, Zn, and Cd were classified as moderately to heavily polluted. Potential ecological risk assessment highlighted Cd as the significant ecological risk factor, indicating considerable heavy metal pollution in the region. (2) Kriging interpolation demonstrated elevated concentrations in the western (mid-upper) and eastern (mid-lower) subregions. Pearson correlation analysis suggested common sources for Cu-Pb-As-Cd and Cr-Zn-Ni. (3) PMF source apportionment identified four primary sources: traffic emissions (38.19%), natural and agricultural mixed sources (34.55%), metal smelting (17.61%), and atmospheric deposition (10.10%). (4) Health risk assessment indicated that the non-carcinogenic risk for both adults and children was within acceptable limits (adults: 0.065; children: 0.12). Carcinogenic risks were also acceptable (adults: 5.67 × 10⁻⁵; children: 6.70 × 10⁻⁵). In conclusion, priority should be given to the control of traffic emissions and agriculturally derived sources in the management of soil heavy metal contamination in this region, while the considerable contribution of smelting activities warrants heightened attention. This study provides a scientific basis for the prevention, control, and targeted remediation of regional soil heavy metal pollution. Full article