Search Results (742)

The utilisation of edible insects for human nutrition is a long-standing practice in many parts of the globe, and is being gradually introduced into countries without an entomophagic tradition as well. These unconventional sources of protein of animal origin have arisen as a sustainable alternative to other animal protein sources, such as meat. This review intends to present the compilation of data in the scientific literature on the chemical composition and nutritional value of the bee brood of A. mellifera species and subspecies as edible foods. For this, a comprehensive search of the scientific literature was carried out using the databases ScienceDirect, Scopus, Pub-Med, BOn, and SciELO. Appropriate keywords were used for the search to reach the research works that addressed the topics of the review. The results showed that bee brood has considerable quantities of protein, fat and carbohydrates. The most abundant amino acids are leucine and lysine (these two being essential amino acids) and aspartic acid, glutamic acid, and proline (these three being non-essential amino acids). As for the fatty acids, bee broods contain approximately equal fractions of saturated and monounsaturated fatty acids, while the polyunsaturated fatty acids are negligible. The dietary minerals present in higher quantities are potassium, phosphorus, and magnesium, and the most abundant vitamins are vitamin C and niacin; choline is also present, although it is not a true vitamin. Although bee brood from A. mellifera has potential for human consumption as a nutrient-rich food, there are still many aspects that need to be further studied in the future, such as safety and hazards linked to possible regular consumption. Full article

Generative AI has been gaining attention across various creative domains. In particular, MusicGen stands out as a representative approach capable of generating music based on text or audio inputs. However, it has limitations in producing high-quality outputs for specific genres and fully reflecting user intentions. This paper proposes a prompt tuning technique that effectively adjusts the output quality of MusicGen without modifying its original parameters and optimizes its ability to generate music tailored to specific genres and styles. Experiments were conducted to compare the performance of the traditional MusicGen with the proposed method and evaluate the quality of generated music using the Contrastive Language-Audio Pretraining (CLAP) and Kullback–Leibler Divergence (KLD) scoring approaches. The results demonstrated that the proposed method significantly improved the output quality and musical coherence, particularly for specific genres and styles. Compared with the traditional model, the CLAP score was increased by 0.1270, and the KLD score was increased by 0.00403 on average. The effectiveness of prompt tuning in optimizing the performance of MusicGen validated the proposed method and highlighted its potential for advancing generative AI-based music generation tools. Full article

Interferometric fiber optic hydrophones (IFOHs) are highly sensitive for underwater acoustic detection but face challenges owing to the trade-off between laser monochromaticity and coherence length. In this study, we propose a pseudo-random binary sequence (PRBS) phase modulation method for laser coherence length control, establishing the first theoretical model that quantitatively links PRBS parameter to coherence length, elucidating the mechanism underlying its suppression of parasitic interference noise. Furthermore, our research findings demonstrate that while reducing the laser coherence length effectively mitigates parasitic interference noise in IFOHs, this reduction also leads to elevated background noise caused by diminished interference visibility. Consequently, the modulation of coherence length requires a balanced optimization approach that not only suppresses parasitic noise but also minimizes visibility-introduced background noise, thereby determining the system-specific optimal coherence length. Through theoretical modeling and experimental validation, we determined that for IFOH systems with a 500 ns delay, the optimal coherence lengths for link fibers of 3.3 km and 10 km are 0.93 m and 0.78 m, respectively. At the optimal coherence length, the background noise level in the 3.3 km system reaches −84.5 dB (re: rad/√Hz @1 kHz), representing an additional noise suppression of 4.5 dB beyond the original suppression. This study provides a comprehensive theoretical and experimental solution to the long-standing contradiction between high laser monochromaticity, stability and appropriate coherence length, establishing a coherence modulation noise suppression framework for hydrophones, gyroscopes, distributed acoustic sensing (DAS), and other fields. Full article

Background/Objectives: Motor creativity is a vital component of preschoolers’ growth and development. However, its underlying determinants remain largely underexplored. This study investigates the interrelationship among playful behavior, social profile, and motor creativity in preschool children, emphasizing its implications for holistic health and development. Methods: A total of 200 children and their kindergarten teachers from Greece participated in the study. The Children’s Playfulness Scale (CPS) was employed to assess the children’s playfulness, while a sociometric test was used to evaluate their social standing within peer groups. Motor creativity was measured through TCAM, a performance-based test focusing on fluency, imagination, and originality. Results: The findings revealed that the dimensions of playful behavior, particularly motor and social playfulness, significantly and positively influenced motor creativity, a core component of physical and mental health in early childhood. Conversely, certain aspects of social behavior had a negative association with imaginative capacities. Conclusions: The study underscores the critical role of movement-based playful activities in fostering children’s physical, emotional, cognitive, and social health. It highlights the need for educators to design developmentally appropriate motor play activities that cultivate creativity and social integration, promoting a balanced and health-oriented early education framework. The results contribute to educational policy and practice by reinforcing the importance of structured motor play in supporting preschoolers’ well-being and comprehensive development. Full article

The Atlantic chub mackerel, Scomber colias, is sold in Spain, as well as another species of the genus, like the Atlantic mackerel, S. scombrus, often mistaken to be the same fish. This study aims to analyse the risk of human anisakiosis through the consumption of S. colias, and to clarify if these two species differ regarding this risk. A total of 250 S. colias (125 originating from the Atlantic and 125 from the Mediterranean) were helminthologically analysed using conventional parasitological techniques. Concerning Ascaridoid nematodes, the prevalence of Anisakis type I was higher in the Atlantic than in the Mediterranean. The presence of three other helminth parasites stands out, two other Ascaridoid nematodes, the larvae of Contracaecum spp. and Hysterothylacium spp., the latter a food-spoiling and non-pathogenic parasite. The other helminth found was the intestinal adult of the acanthocephalan Rhadinorhynchus pristis, also non-pathogenic. The comparison of the current results with previously published ones by our research group on S. scombrus show that Anisakis type I prevalence was higher in S. scombrus than in S. colias, making the correct differentiation between them necessary, given their varying risk of human anisakiosis. Furthermore, fish label information is important to prevent the risk of anisakiosis for consumers. Full article

This article describes the design and implementation of a Specialized Mental Health Clinical Pastoral Education (CPE) program for clergy and theological students of all spiritual, religious, and cultural backgrounds. Addressing the need for mental health competencies in religious leaders and chaplains, this training equips participants with specialized skills in individual and group mental health spiritual assessment and spiritual care. Program participants become effective members of a multiprofessional team, gain knowledge of mental health philosophies of concordant and discordant spiritual orienting systems, and gain greater relational capacity. The Mental Health CPE Program includes traditional and novel CPE elements: (1) clinical practice, (2) group and individual supervision, (3) didactic presentations and journal clubs, (4) verbatim (Protocols of patient encounters) and case presentations, (5) group leadership training and practica, and (6) experience of faith reflections. This article provides insights into the origins of CPE, a description of the implementation in a free-standing psychiatric hospital, and observed developmental changes of program participants. We include graduates’ anecdotal feedback about their learning experience and its impact on their leadership in chaplaincy and in religious communities. Additionally, we report on areas for future development and further study of the effectiveness of Mental Health CPE. Full article

Robinia pseudoacacia is one of the most widely introduced—but also controversial—tree species in Europe. On the one hand, it is valued for its productivity, timber quality, and melliferous blossom. On the other hand, it is highly invasive and causes habitat change and homogenization. The aim of the study reported on here was to assess the genetic diversity of selected R. pseudoacacia stands in Lithuania in districts with the highest black locust stands frequency and to evaluate its spatial distribution in self-establishing stands. To achieve this aim, we employed four nuclear SSR loci (Rops 02, Rops 05, Rops 06, and Rops 08) and investigated the genetic diversity of five R. pseudoacacia plots. The study results reveal that R. pseudoacacia in Lithuania is genetically diverse (the average allele number per plot was 3.66, and the average Ho was 0.83). R. pseudoacacia in the plots forms tight clonal groups that hardly intermix with each other; it also spreads by seeds (66 single-copy genotypes were found in total in all 5 investigated plots). R. pseudoacacia stands in Lithuania originate from different seed sources and from different introduction events, as revealed by the allelic pattern, genetic diversity, and genetic differentiation among the research plots. Full article

Objective: Given the side effects and reduced efficacy of conventional local anesthetics in inflammatory conditions, there is a compelling need for complementary alternative medicine (CAM), particularly those based on phytochemicals. While a previous study showed that in vivo local injection of (-)-epigallocatechin-3-gallate (EGCG) into the peripheral receptive field suppresses the excitability of rat trigeminal ganglion (TG) neurons in the absence of inflammation, the acute effects of EGCG in vivo, especially on TG neurons under inflammatory conditions, are still unknown. We aimed to determine if acute local EGCG administration into inflamed tissue effectively attenuates the excitability of nociceptive TG neurons evoked by mechanical stimulation. Methods: The escape reflex threshold was measured to assess hyperalgesia caused by complete Freund’s adjuvant (CFA)-induced inflammation. To assess neuronal activity, extracellular single-unit recordings were performed on TG neurons in anesthetized CFA-inflamed rats in response to orofacial mechanical stimulation. Results: The mechanical escape threshold was significantly lower in CFA-inflamed rats compared to before CFA injection. EGCG (1–10 mM) reversibly and dose-dependently inhibited the mean firing frequency of TG neurons evoked by both non-noxious and noxious mechanical stimuli (p < 0.05). For comparison, 1% lidocaine (37 mM), a local anesthetic, also caused reversible inhibition of the mean firing frequency in inflamed TG neurons responding to mechanical stimuli. Importantly, 10 mM EGCG produced a significantly greater magnitude of inhibition on TG neuronal discharge frequency than 1% lidocaine (noxious, lidocaine vs. EGCG, 19.7 ± 3.3% vs. 42.3 ± 3.4%, p < 0.05). Conclusions: Local injection of EGCG into inflamed tissue effectively suppresses the excitability of nociceptive primary sensory TG neurons, as indicated by these findings. Significantly, locally administered EGCG exerted a more potent local analgesic action compared to conventional voltage-gated sodium channel blockers. This heightened efficacy originates from EGCG’s ability to inhibit both generator potentials and action potentials directly at nociceptive primary nerve terminals. As a result, EGCG stands out as a compelling candidate for novel analgesic development, holding particular relevance for CAM strategies. Full article

The distribution of the health workforce affects the availability of health service delivery to the public. In practice, the demographic and geographic maldistribution of the health workforce is a long-standing national crisis. In this study, we present an approach based on Functional Principal Component Analysis (FPCA) of data to identify patterns in the availability of health workers across different regions of Kazakhstan in order to forecast their needs up to 2033. FPCA was applied to the data to reduce dimensionality and capture common patterns across regions. To evaluate the forecasting performance of the model, we employed rolling origin cross-validation with an expanding window. The resulting scores were forecasted one year ahead using Autoregressive Integrated Moving Average (ARIMA) and Long Short-Term Memory (LSTM) methods. LSTM showed higher accuracy compared to ARIMA. The use of the FPCA method allowed us to identify national and regional trends in the dynamics of the number of doctors. We identified regions with different growth rates, highlighting where the most and least intensive growth is taking place. Based on the FPSA, we have predicted the need for doctors in each region in the period up to 2033. Our results show that the FPCA can serve as a significant tool for analyzing the situation relating to human resources in healthcare and be used for an approximate assessment of future needs for medical personnel. Full article

The decommissioning and dismantling of nuclear research reactors can lead to a large amount of low- and intermediate-level radioactive waste. For repositories, the materials must be kept confined and safety must be ensured for extended time spans. Waste is encapsulated in concrete, which leads to alkaline conditions with pH values of 12 and higher. This can be advantageous for some radionuclides due to their precipitation at high pH. For other materials, such as reactive metals, however, it can be disadvantageous because it might foster their corrosion. The Studsvik R2 research reactor contained an AlMg3.5 alloy with a composition close to that of commercial Al5154 for its core internals and the reactor tank. Aluminum corrosion is known to start rapidly due to the formation of an oxidation layer, which later functions as natural protection for the surface. The corrosion can lead to pressure build-up through the accompanied production of hydrogen gas. This can lead to cracks in the concrete, which can be pathways for radioactive nuclides to migrate and must therefore be prevented. In this study, unirradiated rod-shaped samples were cut from the same material as the original reactor tank manufacture. They were embedded in concrete with elevated water–cement ratios of 0.7 compared to regular commercial concrete (ca. 0.45) to ensure water availability throughout all of the experiments. The sample containers were stored in pressure vessels with attached high-definition pressure gauges to read the hydrogen-induced pressure build-up. A second set of samples were exposed in simplified artificial cement–water to study similarities in corrosion characteristics between concrete and cement–water. Additionally, the samples were exposed to concrete and cement–water in free-standing sample containers for deconstructive examinations. In concrete, the corrosion rates started extremely high, with values of more than 10,000 µm/y, and slowed down to less than 500 µm/y after 2000 h, which resulted in visible channels inside the concrete. In the cement–water, the samples showed similar behavior after early fluctuations, most likely caused by the surface coverage of hydrogen bubbles. These trends were further supported by mass loss evaluations. Full article

Cocktail-type catalysis represents a significant shift in the understanding of catalytic processes, recognizing that multiple interconverting species—such as metal complexes, clusters, and nanoparticles—can coexist and cooperate within a single reaction environment. Originating from mechanistic studies on palladium-catalyzed systems, this concept challenges the classical division between homogeneous and heterogeneous catalysis. Instead, it introduces a dynamic framework where catalysts adapt and evolve under reaction conditions, often enhancing efficiency, selectivity, and durability. Using advanced spectroscopic, microscopic, and computational techniques, researchers have visualized the formation and transformation of catalytic species in real time. The cocktail-type approach has since been extended to platinum, nickel, copper, and other transition metals, revealing a general principle in catalysis. This approach not only resolves long-standing mechanistic inconsistencies, but also opens new directions for catalyst design, green chemistry, and sustainable industrial applications. Embracing the complexity of catalytic systems may redefine future strategies in both fundamental research and applied catalysis. Full article

Environmental concerns drive the search for sustainable organic alternatives in horticultural substrates. This review critically examines three agro-industry renewable byproducts—wood fiber, coffee silverskin, and brewer’s spent grain—as partial peat substitutes. We aimed to comprehensively analyze their origin, processing methods, current applications, and key physical, hydrological, and chemical properties relevant to horticultural use. In soilless culture, wood fiber can be used as a stand-alone substrate. When incorporated at 30–50% (v/v) in peat mixtures, it supports plant growth comparable to peat; however, higher proportions may restrict water and nutrient availability. Coffee silverskin demonstrates high water retention and nutrient content, but its inherent phytotoxicity requires pre-treatment (e.g., co-composting); at concentrations up to 20%, it shows promise for potted ornamental crops. Brewer’s spent grain is nutrient-rich but demands careful management due to its rapid decomposition and potential salinity issues; inclusion rates around 10% have shown beneficial effects. In conclusion, when used appropriately in blends, these bio-based byproducts represent viable alternatives to reduce peat dependence in vegetable and ornamental cultivation, contributing to more sustainable horticultural practices. Future research should optimize pre-treatment methods for coffee silverskin and brewer’s spent grain, investigate long-term stability in diverse cropping systems, and explore novel combinations with other organic waste streams to develop circular horticultural substrates. Full article

The Illustrated Commentary on the Wuzhen Pian Based on the Zhouyi (周易悟真篇圖注 Zhouyi Wuzhen Pian Tuzhu), authored by the Ming dynasty Confucian scholar Cheng Yiming 程易明, is an illustrated alchemical text that integrates the elixir methodology of Wuzhen pian 悟真篇 (the Awakening to Reality) with the images and numbers (xiangshu 象數) system of The Book of Changes (Zhouyi 周易). Centered on Daoist alchemical theory and elucidated through “Yijing diagrams” (yitu 易圖, diagrams based on the Yijing), it stands as a masterpiece within the tradition of alchemical Yijing studies (dandao yixue 丹道易學). Building on a review of the scholarly history of The Wuzhen Pian, this article focuses on the alchemical Yijing diagrams (dandao yitu 丹道易圖) in the Illustrated Commentary, exploring their terminological definitions, theoretical origins, and diagrammatic systems. By analyzing the structure of cosmology and internal alchemy practice theory (neidan gongfulun 內丹工夫論) as presented in these diagrams, this article demonstrates that the Illustrated Commentary not only inherits the theoretical legacy of early Yijing diagram scholars such as Chen Tuan (陳摶) and Yu Yan (俞琰), but also displays a unique systematic and intuitive approach to illustrating neidan practices through xiangshu diagrams (象數圖解). Notably, diagrams such as “Mundane Continuation vs. Alchemical Inversion” (shunfan nixian 順凡逆仙), the “Three-Five-One Mathematical Model” (sanwuyi shuli moxing 三五一數理模型), and the “Fire Phases” (huohou 火候) reveal attempts to construct an alchemical theoretical system centered on Yijing diagrams. The article further posits that the Illustrated Commentary bridges the gap between images–numbers Yijing studies (xiangshu yixue 象數易學) and alchemical visual hermeneutics, offering a fresh perspective centered on internal alchemy for the study of “Yijing Diagram Studies” (yitu xue 易圖學). Full article

In this study, the treatment of pharmaceutical tail water (PTW) by coagulation, Fenton combined with membrane bioreactor (MBR), was studied. Optimal parameters were obtained according to batch experiment and central composite design (CCD). Results showed that Polymeric Ferric Sulfate (PFS) was the best coagulant for original pharmaceutical tailwater due to less dosage and higher removal efficiency to TOC, COD, NH₄⁺-N and UV_254m, with the optimized pH = 7.25 and 0.53 g/L PFS dosage. The best coagulation performance was achieved when the mixer was stirred at 250 rpm for 3 min, 60 rpm for 10 min, and then left to stand for 60 min. Coagulation mainly removed organics with molecular weight above 10 kDa. After treated by coagulation, 43.1% TOC removal efficiency of PTW was obtained by Fenton reaction with 11.6 mmol/L H₂O₂, 3.0 mmol/L FeSO₄, pH = 3.3 and T = 50 min. A type of common macromolecule aromatic amino acid compounds which located Ex = 250 nm and Em = 500 nm was the main reason that caused the high TOC concentration in the effluent. Stable COD and NH₄⁺-N removal efficiencies in the MBR reactor within 10 d were observed when the mixture of pre-treated PTW (20%, v) and domestic sewage (80%, v) was fed into the MBR reactor, and over 95% COD and 50% NH₄⁺-N were removed. One kind of amino acid similar to tryptophan was the prime reason that caused PTW resistance to be degraded. Analysis of the microorganism community in the MBR suggested that norank_f__Saprospiraceae was the key microorganism in degrading of PTW. Full article

An approach is presented to resolve key paradoxes in black hole physics through the application of complex Riemannian spacetime. We extend the Schwarzschild metric into the complex domain, employing contour integration techniques to remove singularities while preserving the essential features of the original solution. A new regularized radial coordinate is introduced, leading to a singularity-free description of black hole interiors. Crucially, we demonstrate how this complex extension resolves the long-standing paradox of event horizon formation occurring only in the infinite future of distant observers. By analyzing trajectories in complex spacetime, we show that the horizon can form in finite complex time, reconciling the apparent contradiction between proper and coordinate time descriptions. This approach also provides a framework for the analytic continuation of information across event horizons, resolving the Hawking information paradox. We explore the physical interpretation of the complex extension versus its projection onto real spacetime. The gravitational collapse of a dust sphere with negligible dust is explored in the complex spacetime extension. The approach offers a mathematically rigorous framework for exploring quantum gravity effects within the context of classical general relativity. Full article