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14 pages, 1735 KB  
Article
Entanglement Negativity and Exceptional-Point Signatures in a PT-Symmetric Non-Hermitian XY Dimer: Parameter Regimes and Directional-Coupler Mapping
by Linzhi Jiang, Weicheng Miao, Wen-Yang Sun and Wenchao Ma
Photonics 2025, 12(12), 1239; https://doi.org/10.3390/photonics12121239 - 18 Dec 2025
Cited by 1 | Viewed by 854
Abstract
We investigate a non-Hermitian two-spin XY model driven by alternating real and imaginary transverse fields and derive an explicit analytic formula for the ground-state entanglement negativity. This provides a systematic analytic characterization of how ground-state entanglement behaves across PT-symmetry breaking in a non-Hermitian [...] Read more.
We investigate a non-Hermitian two-spin XY model driven by alternating real and imaginary transverse fields and derive an explicit analytic formula for the ground-state entanglement negativity. This provides a systematic analytic characterization of how ground-state entanglement behaves across PT-symmetry breaking in a non-Hermitian spin dimer. In the PT-symmetric regime, the anisotropy γ enhances entanglement, whereas the real field h0 suppresses it; in the PT-broken regime dominated by φ3, the negativity decreases monotonically with the imaginary field η0. Moreover, the first derivative of the negativity exhibits a cusp-type non-analyticity at the exceptional point (EP), consistent with the ground-state phase boundary and revealing a direct correspondence between entanglement transitions and exceptional-point physics. To facilitate implementation in integrated quantum photonics, we map h0,η0,γ onto the device parameters Δβ,g,κ of a PT-symmetric directional coupler and propose a two-qubit quantum state tomography readout based on local Pauli measurements, thereby offering a concrete entanglement-based probe of exceptional-point signatures in a realistic photonic platform. Within this model, we identify parameter regimes for observing this signature: a cusp feature is expected near Δβ0 and gκ, which remains observable under small detuning and moderate loss mismatch. These results offer a testable avenue for entanglement-based probing of PT-symmetry breaking and may inform device characterization and quantitative assessment in integrated quantum photonics. These combined advances provide both analytical insight into non-Hermitian entanglement structure and a feasible route toward experimentally diagnosing PT-symmetry breaking using entanglement. Full article
(This article belongs to the Special Issue Quantum Optics: Communication, Sensing, Computing, and Simulation)
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8 pages, 4923 KB  
Proceeding Paper
A Hardware Measurement Platform for Quantum Current Sensors
by Frederik Hoffmann, Ann-Sophie Bülter, Ludwig Horsthemke, Dennis Stiegekötter, Jens Pogorzelski, Markus Gregor and Peter Glösekötter
Eng. Proc. 2025, 101(1), 11; https://doi.org/10.3390/engproc2025101011 - 4 Aug 2025
Viewed by 1616
Abstract
A concept towards current measurement in low and medium voltage power distribution networks is presented. The concentric magnetic field around the current-carrying conductor should be measured using a nitrogen-vacancy quantum magnetic field sensor. A bottleneck in current measurement systems is the readout electronics, [...] Read more.
A concept towards current measurement in low and medium voltage power distribution networks is presented. The concentric magnetic field around the current-carrying conductor should be measured using a nitrogen-vacancy quantum magnetic field sensor. A bottleneck in current measurement systems is the readout electronics, which are usually based on optically detected magnetic resonance (ODMR). The idea is to have a hardware that tracks up to four resonances simultaneously for the detection of the three-axis magnetic field components and the temperature. Normally, expensive scientific instruments are used for the measurement setup. In this work, we present an electronic device that is based on a Zynq 7010 FPGA (Red Pitaya) with an add-on board, which has been developed to control the excitation laser, the generation of the microwaves, and interfacing the photodiode, and which provides additional fast digital outputs. The T1 measurement was chosen to demonstrate the ability to read out the spin of the system. Full article
(This article belongs to the Proceedings of The 11th International Conference on Time Series and Forecasting)
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13 pages, 5148 KB  
Article
Deep Learning-Powered Super Resolution Reconstruction Improves 2D T2-Weighted Turbo Spin Echo MRI of the Hippocampus
by Elisabeth Sartoretti, Thomas Sartoretti, Alex Alfieri, Tobias Hoh, Alexander Maurer, Manoj Mannil, Christoph A. Binkert and Sabine Sartoretti-Schefer
Appl. Sci. 2025, 15(15), 8202; https://doi.org/10.3390/app15158202 - 23 Jul 2025
Viewed by 1442
Abstract
Purpose: To assess the performance of 2D T2-weighted (w) Turbo Spin Echo (TSE) MRI reconstructed with a deep learning (DL)-powered super resolution reconstruction (SRR) algorithm combining compressed sensing (CS) denoising and resolution upscaling for high-resolution hippocampal imaging in patients with (epileptic) seizures and [...] Read more.
Purpose: To assess the performance of 2D T2-weighted (w) Turbo Spin Echo (TSE) MRI reconstructed with a deep learning (DL)-powered super resolution reconstruction (SRR) algorithm combining compressed sensing (CS) denoising and resolution upscaling for high-resolution hippocampal imaging in patients with (epileptic) seizures and suspected hippocampal pathology. Methods: A 2D T2w TSE coronal hippocampal sequence with compressed sense (CS) factor 1 (scan time 270 s) and a CS-accelerated sequence with a CS factor of 3 (scan time 103 s) were acquired in 28 patients. Reconstructions using the SRR algorithm (CS 1-SSR-s and CS 3-SSR-s) were additionally obtained in real time. Two readers graded the images twice, based on several metrics (image quality; artifacts; visualization of anatomical details of the internal hippocampal architecture (HIA); visibility of dentate gyrus/pes hippocampi/fornix/mammillary bodies; delineation of gray and white matter). Results: Inter-readout agreement was almost perfect (Krippendorff’s alpha coefficient = 0.933). Compared to the CS 1 sequence, the CS 3 sequence significantly underperformed in all 11 metrics (p < 0.001-p = 0.04), while the CS 1-SRR-s sequence outperformed in terms of overall image quality and visualization of the left HIA and right pes hippocampi (p < 0.001-p < 0.04) but underperformed in terms of presence of artifacts (p < 0.01). Lastly, relative to the CS 1 sequence, the CS 3-SRR-s sequence was graded worse in terms of presence of artifacts (p < 0.003) but with improved visualization of the right pes hippocampi (p = 0.02). Conclusion: DL-powered SSR demonstrates its capacity to enhance imaging performance by introducing flexibility in T2w hippocampal imaging; it either improves image quality for non-accelerated imaging or preserves acceptable quality in accelerated imaging, with the additional benefit of a reduced scan time. Full article
(This article belongs to the Special Issue Advances in Diagnostic Radiology)
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15 pages, 3552 KB  
Article
Fast Hadamard-Encoded 7T Spectroscopic Imaging of Human Brain
by Chan Hong Moon, Frank S. Lieberman, Hoby P. Hetherington and Jullie W. Pan
Tomography 2025, 11(1), 7; https://doi.org/10.3390/tomography11010007 - 13 Jan 2025
Viewed by 2422
Abstract
Background/Objectives: The increased SNR available at 7T combined with fast readout trajectories enables accelerated spectroscopic imaging acquisitions for clinical applications. In this report, we evaluate the performance of a Hadamard slice encoding strategy with a 2D rosette trajectory for multi-slice fast spectroscopic [...] Read more.
Background/Objectives: The increased SNR available at 7T combined with fast readout trajectories enables accelerated spectroscopic imaging acquisitions for clinical applications. In this report, we evaluate the performance of a Hadamard slice encoding strategy with a 2D rosette trajectory for multi-slice fast spectroscopic imaging at 7T. Methods: Moderate-TE (~40 ms) spin echo and J-refocused polarization transfer sequences were acquired with simultaneous Hadamard multi-slice excitations and rosette in-plane encoding. The moderate spin echo sequence, which targets singlet compounds (i.e., N-acetyl aspartate, creatine, and choline), uses cascaded multi-slice RF excitation pulses to minimize the chemical shift dispersion error. The J-refocused sequence targets coupled spin systems (i.e., glutamate and myo-inositol) using simultaneous multi-slice excitation to maintain the same TE across all slices. A modified Hadamard slice encoding strategy was used to decrease the peak RF pulse amplitude of the simultaneous multi-slice excitation pulse for the J-refocused acquisition. Results: The accuracy of multi-slice and single-slice rosette spectroscopic imaging (RSI) is comparable to conventional Cartesian-encoded spectroscopic imaging (CSI). Spectral analyses for the J-refocused studies of glutamate and myo-inositol show that the Cramer Rao lower bounds are not significantly different between the fast RSI and conventional CSI studies. Linear regressions of creatine/N-acetyl aspartate and glutamate/N-acetyl aspartate with tissue gray matter content are consistent with literature values. Conclusions: With minimal gradient demands and fast acquisition times, the 2.2 min to 9 min for single- to four-slice RSI acquisitions are well tolerated by healthy subjects and tumor patients, and show results that are consistent with clinical outcomes. Full article
(This article belongs to the Section Neuroimaging)
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24 pages, 1486 KB  
Article
Finite Nuclear Size Effect on the Relativistic Hyperfine Splittings of 2s and 2p Excited States of Hydrogen-like Atoms
by Katharina Lorena Franzke and Uwe Gerstmann
Foundations 2024, 4(4), 513-536; https://doi.org/10.3390/foundations4040034 - 1 Oct 2024
Cited by 2 | Viewed by 4239
Abstract
Hyperfine splittings play an important role in quantum information and spintronics applications. They allow for the readout of the spin qubits, while at the same time providing the dominant mechanism for the detrimental spin decoherence. Their exact knowledge is thus of prior relevance. [...] Read more.
Hyperfine splittings play an important role in quantum information and spintronics applications. They allow for the readout of the spin qubits, while at the same time providing the dominant mechanism for the detrimental spin decoherence. Their exact knowledge is thus of prior relevance. In this work, we analytically investigate the relativistic effects on the hyperfine splittings of hydrogen-like atoms, including finite-size effects of the nucleis’ structure. We start from exact solutions of Dirac’s equation using different nuclear models, where the nucleus is approximated by (i) a point charge (Coulomb potential), (ii) a homogeneously charged full sphere, and (iii) a homogeneously charged spherical shell. Equivalent modelling has been done for the distribution of the nuclear magnetic moment. For the 1s ground state and 2s excited state of the one-electron systems H1, H2, H3, and He+3, the calculated finite-size related hyperfine shifts are quite similar for the different structure models and in excellent agreement with those estimated by comparing QED and experiment. This holds also in a simplified approach where relativistic wave functions from a Coulomb potential combined with spherical-shell distributed nuclear magnetic moments promises an improved treatment without the need for an explicit solution of Dirac’s equation within the nuclear core. Larger differences between different nuclear structure models are found in the case of the anisotropic 2p3/2 orbitals of hydrogen, rendering these excited states as promising reference systems for exploring the proton structure. Full article
(This article belongs to the Section Physical Sciences)
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9 pages, 623 KB  
Article
Suppressing Thermal Noise to Sub-Millikelvin Level in a Single-Spin Quantum System Using Realtime Frequency Tracking
by Zhiyi Hu, Jingyan He, Runchuan Ye, Xue Lin, Feifei Zhou and Nanyang Xu
Micromachines 2024, 15(7), 911; https://doi.org/10.3390/mi15070911 - 13 Jul 2024
Viewed by 2569
Abstract
A single nitrogen-vacancy (NV) center in a diamond can be used as a nanoscale sensor for magnetic field, electric field or nuclear spins. Due to its low photon detection efficiency, such sensing processes often take a long time, suffering from an electron spin [...] Read more.
A single nitrogen-vacancy (NV) center in a diamond can be used as a nanoscale sensor for magnetic field, electric field or nuclear spins. Due to its low photon detection efficiency, such sensing processes often take a long time, suffering from an electron spin resonance (ESR) frequency fluctuation induced by the time-varying thermal perturbations noise. Thus, suppressing the thermal noise is the fundamental way to enhance single-sensor performance, which is typically achieved by utilizing a thermal control protocol with a complicated and highly costly apparatus if a millikelvin-level stabilization is required. Here, we analyze the real-time thermal drift and utilize an active way to alternately track the single-spin ESR frequency drift in the experiment. Using this method, we achieve a temperature stabilization effect equivalent to sub-millikelvin (0.8 mK) level with no extra environmental thermal control, and the spin-state readout contrast is significantly improved in long-lasting experiments. This method holds broad applicability for NV-based single-spin experiments and harbors the potential for prospective expansion into diverse nanoscale quantum sensing domains. Full article
(This article belongs to the Special Issue Emerging Quantum Optical Devices and Their Applications)
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17 pages, 2135 KB  
Article
Stability of Radiomic Features against Variations in Lesion Segmentations Computed on Apparent Diffusion Coefficient Maps of Breast Lesions
by Mona Pistel, Luise Brock, Frederik Bernd Laun, Ramona Erber, Elisabeth Weiland, Michael Uder, Evelyn Wenkel, Sabine Ohlmeyer and Sebastian Bickelhaupt
Diagnostics 2024, 14(13), 1427; https://doi.org/10.3390/diagnostics14131427 - 3 Jul 2024
Cited by 3 | Viewed by 1872
Abstract
Diffusion-weighted imaging (DWI) combined with radiomics can aid in the differentiation of breast lesions. Segmentation characteristics, however, might influence radiomic features. To evaluate feature stability, we implemented a standardized pipeline featuring shifts and shape variations of the underlying segmentations. A total of 103 [...] Read more.
Diffusion-weighted imaging (DWI) combined with radiomics can aid in the differentiation of breast lesions. Segmentation characteristics, however, might influence radiomic features. To evaluate feature stability, we implemented a standardized pipeline featuring shifts and shape variations of the underlying segmentations. A total of 103 patients were retrospectively included in this IRB-approved study after multiparametric diagnostic breast 3T MRI with a spin-echo diffusion-weighted sequence with echoplanar readout (b-values: 50, 750 and 1500 s/mm2). Lesion segmentations underwent shifts and shape variations, with >100 radiomic features extracted from apparent diffusion coefficient (ADC) maps for each variation. These features were then compared and ranked based on their stability, measured by the Overall Concordance Correlation Coefficient (OCCC) and Dynamic Range (DR). Results showed variation in feature robustness to segmentation changes. The most stable features, excluding shape-related features, were FO (Mean, Median, RootMeanSquared), GLDM (DependenceNonUniformity), GLRLM (RunLengthNonUniformity), and GLSZM (SizeZoneNonUniformity), which all had OCCC and DR > 0.95 for both shifting and resizing the segmentation. Perimeter, MajorAxisLength, MaximumDiameter, PixelSurface, MeshSurface, and MinorAxisLength were the most stable features in the Shape category with OCCC and DR > 0.95 for resizing. Considering the variability in radiomic feature stability against segmentation variations is relevant when interpreting radiomic analysis of breast DWI data. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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11 pages, 600 KB  
Communication
Frequency Limits of Sequential Readout for Sensing AC Magnetic Fields Using Nitrogen-Vacancy Centers in Diamond
by Santosh Ghimire, Seong-joo Lee, Sangwon Oh and Jeong Hyun Shim
Sensors 2023, 23(17), 7566; https://doi.org/10.3390/s23177566 - 31 Aug 2023
Cited by 4 | Viewed by 2873
Abstract
The nitrogen-vacancy (NV) centers in diamond have the ability to sense alternating-current (AC) magnetic fields with high spatial resolution. However, the frequency range of AC sensing protocols based on dynamical decoupling (DD) sequences has not been thoroughly explored experimentally. In this work, we [...] Read more.
The nitrogen-vacancy (NV) centers in diamond have the ability to sense alternating-current (AC) magnetic fields with high spatial resolution. However, the frequency range of AC sensing protocols based on dynamical decoupling (DD) sequences has not been thoroughly explored experimentally. In this work, we aimed to determine the sensitivity of the ac magnetic field as a function of frequency using the sequential readout method. The upper limit at high frequency is clearly determined by Rabi frequency, in line with the expected effect of finite DD-pulse width. In contrast, the lower frequency limit is primarily governed by the duration of optical repolarization rather than the decoherence time (T2) of NV spins. This becomes particularly crucial when the repetition (dwell) time of the sequential readout is fixed to maintain the acquisition bandwidth. The equation we provide successfully describes the tendency in the frequency dependence. In addition, at the near-optimal frequency of 1 MHz, we reached a maximum sensitivity of 229 pT/Hz by employing the XY4-(4) DD sequence. Full article
(This article belongs to the Section Sensing and Imaging)
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14 pages, 5075 KB  
Article
Structure, Luminescence and Temperature Detection Capability of [C(NH2)3]M(HCOO)3 (M = Mg2+, Mn2+, Zn2+) Hybrid Organic–Inorganic Formate Perovskites Containing Cr3+ Ions
by Dagmara Stefańska, Adam Kabański, Thi Hong Quan Vu, Marek Adaszyński and Maciej Ptak
Sensors 2023, 23(14), 6259; https://doi.org/10.3390/s23146259 - 9 Jul 2023
Cited by 8 | Viewed by 2711
Abstract
Metal-organic frameworks are of great interest to scientists from various fields. This group also includes organic–inorganic hybrids with a perovskite structure. Recently their structural, phonon, and luminescent properties have been paid much attention. However, a new way of characterization of these materials has [...] Read more.
Metal-organic frameworks are of great interest to scientists from various fields. This group also includes organic–inorganic hybrids with a perovskite structure. Recently their structural, phonon, and luminescent properties have been paid much attention. However, a new way of characterization of these materials has become luminescence thermometry. Herein, we report the structure, luminescence, and temperature detection ability of formate organic–inorganic perovskite [C(NH2)3]M(HCOO)3 (Mg2+, Mn2+, Zn2+) doped with Cr3+ ions. Crystal field strength (Dq/B) and Racah parameters were determined based on diffuse reflectance spectra. It was shown that Cr3+ ions are positioned in the intermediate crystal field or close to it with a Dq/B range of 2.29–2.41. The co-existence of the spin-forbidden and spin-allowed transitions of Cr3+ ions enable the proposal of an approach for remote readout of the temperature. The relative sensitivity (Sr) can be easily modified by sample composition and Cr3+ ions concentration. The luminescent thermometer based on the 2E/4T2g transitions has the relative sensitivity Sr of 2.08%K−1 at 90 K for [C(NH2)3]Mg(HCOO)3: 1% Cr3+ and decrease to 1.20%K−1 at 100 K and 1.08%K−1 at 90 K for Mn2+ and Zn2+ analogs, respectively. Full article
(This article belongs to the Special Issue Optical Thermometry: Concepts, Methods, and Applications)
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34 pages, 11023 KB  
Review
The Influence of the Substrate on the Functionality of Spin Crossover Molecular Materials
by Saeed Yazdani, Jared Phillips, Thilini K. Ekanayaka, Ruihua Cheng and Peter A. Dowben
Molecules 2023, 28(9), 3735; https://doi.org/10.3390/molecules28093735 - 26 Apr 2023
Cited by 21 | Viewed by 4642
Abstract
Spin crossover complexes are a route toward designing molecular devices with a facile readout due to the change in conductance that accompanies the change in spin state. Because substrate effects are important for any molecular device, there are increased efforts to characterize the [...] Read more.
Spin crossover complexes are a route toward designing molecular devices with a facile readout due to the change in conductance that accompanies the change in spin state. Because substrate effects are important for any molecular device, there are increased efforts to characterize the influence of the substrate on the spin state transition. Several classes of spin crossover molecules deposited on different types of surface, including metallic and non-metallic substrates, are comprehensively reviewed here. While some non-metallic substrates like graphite seem to be promising from experimental measurements, theoretical and experimental studies indicate that 2D semiconductor surfaces will have minimum interaction with spin crossover molecules. Most metallic substrates, such as Au and Cu, tend to suppress changes in spin state and affect the spin state switching process due to the interaction at the molecule–substrate interface that lock spin crossover molecules in a particular spin state or mixed spin state. Of course, the influence of the substrate on a spin crossover thin film depends on the molecular film thickness and perhaps the method used to deposit the molecular film. Full article
(This article belongs to the Special Issue Molecular Bistability in Metal Complexes)
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15 pages, 1849 KB  
Article
Comparison of Diagnostic Performance and Image Quality between Topup-Corrected and Standard Readout-Segmented Echo-Planar Diffusion-Weighted Imaging for Cholesteatoma Diagnostics
by Marco Wiesmueller, Wolfgang Wuest, Angelika Mennecke, Matthias Stefan May, Rafael Heiss, Tobit Fuehres, Rolf Janka, Michael Uder, Arnd Doerfler and Frederik Bernd Laun
Diagnostics 2023, 13(7), 1242; https://doi.org/10.3390/diagnostics13071242 - 25 Mar 2023
Viewed by 2800
Abstract
This study compares the diagnostic performance and image quality of single-shot turbo spin-echo DWI (tseDWI), standard readout-segmented DWI (rsDWI), and a modified rsDWI version (topupDWI) for cholesteatoma diagnostics. Thirty-four patients with newly suspected unilateral cholesteatoma were examined on a 1.5 Tesla MRI scanner. [...] Read more.
This study compares the diagnostic performance and image quality of single-shot turbo spin-echo DWI (tseDWI), standard readout-segmented DWI (rsDWI), and a modified rsDWI version (topupDWI) for cholesteatoma diagnostics. Thirty-four patients with newly suspected unilateral cholesteatoma were examined on a 1.5 Tesla MRI scanner. Diagnostic performance was evaluated by calculating and comparing the sensitivity and specificity using histopathological results as the standard of reference. Image quality was independently reviewed by two readers using a 5-point Likert scale evaluating image distortions, susceptibility artifacts, image resolution, lesion conspicuity, and diagnostic confidence. Twenty-five cholesteatomas were histologically confirmed after surgery and originated in the study group. TseDWI showed the highest sensitivity with 96% (95% confidence interval (CI): 88–100%), followed by topupDWI with 92% (95% CI: 81–100%) for both readers. The sensitivity for rsDWI was 76% (95% CI: 59–93%) for reader 1 and 84% (95% CI: 70–98%) for reader 2, respectively. Both tseDWI and topupDWI revealed a specificity of 100% (95% CI: 66–100%) and rsDWI of 89% (95% CI: 52–100%). Both tseDWI and topupDWI showed fewer image distortions and susceptibility artifacts compared to rsDWI. Image resolution was consistently rated best for topupDWI, followed by rsDWI, which both outperformed tseDWI. TopupDWI and tseDWI showed comparable results for lesions’ conspicuity and diagnostic confidence, both outperforming rsDWI. Modified readout-segmented DWI using the topup-correction method is preferable to standard rsDWI and may be regarded as an accurate alternative to single-shot turbo spin-echo DWI in cholesteatoma diagnostics. Full article
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11 pages, 1950 KB  
Article
Coherence Characteristics of a GaAs Single Heavy-Hole Spin Qubit Using a Modified Single-Shot Latching Readout Technique
by Victor Marton, Andrew Sachrajda, Marek Korkusinski, Alex Bogan and Sergei Studenikin
Nanomaterials 2023, 13(5), 950; https://doi.org/10.3390/nano13050950 - 6 Mar 2023
Cited by 8 | Viewed by 3252
Abstract
We present an experimental study of the coherence properties of a single heavy-hole spin qubit formed in one quantum dot of a gated GaAs/AlGaAs double quantum dot device. We use a modified spin-readout latching technique in which the second quantum dot serves both [...] Read more.
We present an experimental study of the coherence properties of a single heavy-hole spin qubit formed in one quantum dot of a gated GaAs/AlGaAs double quantum dot device. We use a modified spin-readout latching technique in which the second quantum dot serves both as an auxiliary element for a fast spin-dependent readout within a 200 ns time window and as a register for storing the spin-state information. To manipulate the single-spin qubit, we apply sequences of microwave bursts of various amplitudes and durations to make Rabi, Ramsey, Hahn-echo, and CPMG measurements. As a result of the qubit manipulation protocols combined with the latching spin readout, we determine and discuss the achieved qubit coherence times: T1, TRabi, T2*, and T2CPMG vs. microwave excitation amplitude, detuning, and additional relevant parameters. Full article
(This article belongs to the Special Issue Semiconductor Quantum Wells and Nanostructures)
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20 pages, 3025 KB  
Article
Hands-On Quantum Sensing with NV Centers in Diamonds
by J. L. Sánchez Toural, V. Marzoa, R. Bernardo-Gavito, J. L. Pau and D. Granados
C 2023, 9(1), 16; https://doi.org/10.3390/c9010016 - 29 Jan 2023
Cited by 13 | Viewed by 19821
Abstract
The physical properties of diamond crystals, such as color or electrical conductivity, can be controlled via impurities. In particular, when doped with nitrogen, optically active nitrogen-vacancy centers (NV), can be induced. The center is an outstanding quantum spin system that [...] Read more.
The physical properties of diamond crystals, such as color or electrical conductivity, can be controlled via impurities. In particular, when doped with nitrogen, optically active nitrogen-vacancy centers (NV), can be induced. The center is an outstanding quantum spin system that enables, under ambient conditions, optical initialization, readout, and coherent microwave control with applications in sensing and quantum information. Under optical and radio frequency excitation, the Zeeman splitting of the degenerate states allows the quantitative measurement of external magnetic fields with high sensitivity. This study provides a pedagogical introduction to the properties of the NV centers as well as a step-by-step process to develop and test a simple magnetic quantum sensor based on color centers with significant potential for the development of highly compact multisensor systems. Full article
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16 pages, 2917 KB  
Article
Tunable Magneto-Plasmonic Nanosensor for Sensitive Detection of Foodborne Pathogens
by Tuhina Banerjee, Nilamben Panchal, Carissa Sutton, Rebekah Elliott, Truptiben Patel, Kajal Kajal, Eniola Arogunyo, Neelima Koti and Santimukul Santra
Biosensors 2023, 13(1), 109; https://doi.org/10.3390/bios13010109 - 7 Jan 2023
Cited by 9 | Viewed by 5098
Abstract
Frequent outbreaks of food-borne pathogens, particularly E. coli O157:H7, continue to impact human health and the agricultural economy tremendously. The required cell count for this pathogenic strain of E. coli O157:H7 is relatively low and hence it is vital to detect at low [...] Read more.
Frequent outbreaks of food-borne pathogens, particularly E. coli O157:H7, continue to impact human health and the agricultural economy tremendously. The required cell count for this pathogenic strain of E. coli O157:H7 is relatively low and hence it is vital to detect at low colony forming unit (CFU) counts. Available detection methods, though sensitive, fall short in terms of timeliness and often require extensive sample processing. To overcome these limitations, we propose a novel magneto-plasmonic nanosensor (MPnS) by integrating surface plasmon resonance (SPR) properties with spin–spin magnetic relaxation (T2 MR) technology. We engineered MPnS by encapsulating several gold nanoparticles (GNPs) within the polymer-coating of iron oxide nanoparticles (IONPs). First, the polyacrylic acid (PAA)-coated IONPs were synthesized using a solvent precipitation method, then gold chloride solution was used to synthesize GNPs and encapsulate them within the PAA-coatings of IONPs in one step. A magnetic separation technique was used to purify the MPnS and the presence of GNPs within IONPs was characterized using transmission electron microscopy (TEM), energy dispersive x-ray spectroscopy (EDS), and other spectroscopic methods. The synthesized MPnS exhibits MR relaxation properties while possessing amplified optical properties than conventional GNPs. This allows for rapid and ultrasensitive detection of E. coli O157:H7 by SPR, T2 MR, and colorimetric readout. Experiments conducted in simple buffer and in milk as a complex media demonstrated that our MPnS-based assay could detect as low as 10 CFUs of this pathogenic strain of E. coli O157:H7 in minutes with no cross-reactivity. Overall, the formulated MPnS is robust and holds great potential for the ultrasensitive detection of E. coli O157:H7 in a simple and timely fashion. Moreover, this platform is highly customizable and can be used for the detection of other foodborne pathogens. Full article
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18 pages, 14281 KB  
Article
CMOS Front End for Interfacing Spin-Hall Nano-Oscillators for Neuromorphic Computing in the GHz Range
by Rafaella Fiorelli, Eduardo Peralías, Roberto Méndez-Romero, Mona Rajabali, Akash Kumar, Mohammad Zahedinejad, Johan Åkerman, Farshad Moradi, Teresa Serrano-Gotarredona and Bernabé Linares-Barranco
Electronics 2023, 12(1), 230; https://doi.org/10.3390/electronics12010230 - 3 Jan 2023
Cited by 2 | Viewed by 5137
Abstract
Spin-Hall-effect nano-oscillators are promising beyond the CMOS devices currently available, and can potentially be used to emulate the functioning of neurons in computational neuromorphic systems. As they oscillate in the 4–20 GHz range, they could potentially be used for building highly accelerated neural [...] Read more.
Spin-Hall-effect nano-oscillators are promising beyond the CMOS devices currently available, and can potentially be used to emulate the functioning of neurons in computational neuromorphic systems. As they oscillate in the 4–20 GHz range, they could potentially be used for building highly accelerated neural hardware platforms. However, due to their extremely low signal level and high impedance at their output, as well as their microwave-range operating frequency, discerning whether the SHNO is oscillating or not carries a great challenge when its state read-out circuit is implemented using CMOS technologies. This paper presents the first CMOS front-end read-out circuitry, implemented in 180 nm, working at a SHNO oscillation frequency up to 4.7 GHz, managing to discern SHNO amplitudes of 100 µV even for an impedance as large as 300 Ω and a noise figure of 5.3 dB300 Ω. A design flow of this front end is presented, as well as the architecture of each of its blocks. The study of the low-noise amplifier is deepened for its intrinsic difficulties in the design, satisfying the characteristics of SHNOs. Full article
(This article belongs to the Special Issue Ultra-Low Voltage CMOS Front-End Design)
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