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30 pages, 3078 KiB  
Review
Smart Polymers and Adaptive Systems in Pilot Suit Engineering: Toward Autonomous, Responsive, and Wearable Flight Technologies
by Hanjing Ma, Yuan He, Yu Ma, Guannan Han, Zhetao Zhang and Baohua Tian
Nanomaterials 2025, 15(16), 1228; https://doi.org/10.3390/nano15161228 - 12 Aug 2025
Abstract
Next-generation pilot suits are evolving into intelligent, adaptive platforms that integrate advanced polymeric materials, smart textiles, and on-body artificial intelligence. High-performance polymers have advanced in mechanical strength, thermal regulation, and environmental resilience, with fabrication methods like electrospinning, weaving, and 3D/4D printing enabling structural [...] Read more.
Next-generation pilot suits are evolving into intelligent, adaptive platforms that integrate advanced polymeric materials, smart textiles, and on-body artificial intelligence. High-performance polymers have advanced in mechanical strength, thermal regulation, and environmental resilience, with fabrication methods like electrospinning, weaving, and 3D/4D printing enabling structural versatility and sensor integration. In particular, functional nanomaterials and hierarchical nanostructures contribute critical properties such as conductivity, flexibility, and responsiveness, forming the foundation for miniaturized sensing and integrated electronics. The integration of flexible fiber-based electronics such as biosensors, strain sensors, and energy systems enables real-time monitoring of physiological and environmental conditions. Coupled with on-body AI for multimodal data processing, autonomous decision-making, and adaptive feedback, these systems enhance pilot safety while reducing cognitive load during flight. This review places a special focus on system-level integration, where polymers and nanomaterials serve as both structural and functional components in wearable technologies. By highlighting the role of nanostructured and functional materials within intelligent textiles, we underline a potential shift toward active human–machine interfaces in aerospace applications. Future trends and advancements in self-healing materials, neuromorphic computing, and dynamic textile systems will further elevate the capabilities of intelligent pilot suits. This review discusses interdisciplinary strategies for developing pilot wearables capable of responding to real-time physiological and operational needs. Full article
(This article belongs to the Special Issue Nanomaterials and Textiles (Second Edition))
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12 pages, 1246 KiB  
Article
Research on Personalized Exercise Volume Optimization in College Basketball Training Based on LSTM Neural Network with Multi-Modal Data Fusion Intervention
by Xiongce Lv, Ye Tao and Yang Xue
Appl. Sci. 2025, 15(16), 8871; https://doi.org/10.3390/app15168871 (registering DOI) - 12 Aug 2025
Abstract
This study addresses the shortcomings of traditional exercise volume assessment methods in dynamic modeling and individual adaptation by proposing a multi-modal data fusion framework based on a spatio-temporal attention-enhanced LSTM neural network for personalized exercise volume optimization in college basketball courses. By integrating [...] Read more.
This study addresses the shortcomings of traditional exercise volume assessment methods in dynamic modeling and individual adaptation by proposing a multi-modal data fusion framework based on a spatio-temporal attention-enhanced LSTM neural network for personalized exercise volume optimization in college basketball courses. By integrating physiological signals (heart rate), kinematic parameters (triaxial acceleration, step count), and environmental data collected from smart wearable devices, we constructed a dynamic weighted fusion mechanism and a personalized correction engine, establishing an evaluation model incorporating BMI correction factors and fitness-level compensation. Experimental data from 100 collegiate basketball trainees (60 males, 40 females; BMI 17.5–28.7) wearing Polar H10 and Xsens MVN devices were analyzed through an 8-week longitudinal study design. The framework integrates physiological monitoring (HR, HRV), kinematic analysis (3D acceleration at 100 Hz), and environmental sensing (SHT35 sensor). Experimental results demonstrate the following: (1) the LSTM-attention model achieves 85.3% accuracy in exercise intensity classification, outperforming traditional methods by 13.2%, with its spatio-temporal attention mechanism effectively capturing high-dynamic movement features such as basketball sudden stops and directional changes; (2) multi-modal data fusion reduces assessment errors by 15.2%, confirming the complementary value of heart rate and acceleration data; (3) the personalized correction mechanism significantly improves evaluation precision for overweight students (error reduction of 13.6%) and beginners (recognition rate increase of 18.5%). System implementation enhances exercise goal completion rates by 10.3% and increases moderate-to-vigorous training duration by 14.7%, providing a closed-loop “assessment-correction-feedback” solution for intelligent sports education. The research contributes methodological innovations in personalized modeling for exercise science and multi-modal time-series data processing. Full article
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45 pages, 9562 KiB  
Article
Wavelet-Based Denoising Strategies for Non-Stationary Signals in Electrical Power Systems: An Optimization Perspective
by Sıtkı Akkaya
Electronics 2025, 14(16), 3190; https://doi.org/10.3390/electronics14163190 - 11 Aug 2025
Abstract
Effective noise elimination is essential for ensuring data reliability in high-accuracy measurement systems. However, selecting the optimal denoising strategy for diverse and non-stationary signal types remains a major challenge. This study presents a wavelet-based denoising optimization framework that systematically identifies and applies the [...] Read more.
Effective noise elimination is essential for ensuring data reliability in high-accuracy measurement systems. However, selecting the optimal denoising strategy for diverse and non-stationary signal types remains a major challenge. This study presents a wavelet-based denoising optimization framework that systematically identifies and applies the most suitable noise reduction model for each signal segment. By evaluating multiple wavelet types and thresholding strategies, the proposed method enables adaptive and automated selection tailored to the specific characteristics of each signal. The framework was validated using synthetic, open-access, and experimentally acquired signals in both reference-based and reference-free scenarios. Extensive testing covered signals from power quality disturbance (PQD) events, electrocardiogram (ECG) data, and electroencephalogram (EEG) recordings, all of which represent critical applications where signal integrity under noise is essential. The method achieved optimal model selection in 22.15 s (across 4558 iterations) on a standard PC, with an average denoising time of 4.86 ms per signal window. These results highlight its potential for real-time and embedded applications, including smart grid monitoring systems, wearable health devices, and automated biomedical diagnostic platforms, where adaptive, fast, and reliable denoising is vital. The framework’s versatility makes it highly relevant for deployment in smart grid monitoring systems and intelligent energy infrastructures requiring robust signal conditioning. Full article
(This article belongs to the Special Issue Smart Grid Technologies and Energy Conversion Systems)
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22 pages, 706 KiB  
Article
Technological Innovation and the Role of Smart Surveys in the Industrial Context
by Massimiliano Giacalone, Chiara Marciano, Claudia Pipino, Gianfranco Piscopo and Stefano Marra
Appl. Sci. 2025, 15(16), 8832; https://doi.org/10.3390/app15168832 - 11 Aug 2025
Abstract
Technological innovation has significantly transformed the field of statistics, not only in data analysis but also in data collection. Traditional methods based on direct observation have evolved into hybrid approaches that combine passively collected data (e.g., from GPS or accelerometers) with active user [...] Read more.
Technological innovation has significantly transformed the field of statistics, not only in data analysis but also in data collection. Traditional methods based on direct observation have evolved into hybrid approaches that combine passively collected data (e.g., from GPS or accelerometers) with active user input through digital interfaces. This evolution has led to Smart Surveys—next-generation tools that leverage smart devices, such as smartphones and wearables, to collect data actively (via questionnaires or images) and passively (via embedded sensors). Smart Surveys offer strategic value in industrial contexts by enabling real-time data collection on worker behavior, environments, and operational conditions. However, the heterogeneity of such data poses challenges in management, integration, and quality assurance. This study proposes a modular system architecture incorporating gamification elements to enhance user participation, particularly among hard-to-reach worker segments, such as mobile or shift workers. By leveraging motivational strategies and interactive feedback mechanisms, the system seeks to foster greater engagement while addressing critical data security and privacy concerns within industrial Internet of Things (IoT) environments. Full article
(This article belongs to the Special Issue Applications of Industrial Internet of Things (IIoT) Platforms)
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26 pages, 571 KiB  
Article
SHARP: Blockchain-Powered WSNs for Real-Time Student Health Monitoring and Personalized Learning
by Zeqiang Xie, Zijian Li and Xinbing Liu
Sensors 2025, 25(16), 4885; https://doi.org/10.3390/s25164885 - 8 Aug 2025
Viewed by 239
Abstract
With the rapid advancement of the Internet of Things (IoT), artificial intelligence (AI), and blockchain technologies, educational research has increasingly explored smart and personalized learning systems. However, current approaches often suffer from fragmented integration of health monitoring and instructional adaptation, insufficient prediction accuracy [...] Read more.
With the rapid advancement of the Internet of Things (IoT), artificial intelligence (AI), and blockchain technologies, educational research has increasingly explored smart and personalized learning systems. However, current approaches often suffer from fragmented integration of health monitoring and instructional adaptation, insufficient prediction accuracy of physiological states, and unresolved concerns regarding data privacy and security. To address these challenges, this study introduces SHARP, a novel blockchain-enhanced wireless sensor networks (WSNs) framework designed for real-time student health monitoring and personalized learning in smart educational environments. Wearable sensors enable continuous collection of physiological data, including heart rate variability, body temperature, and stress indicators. A deep neural network (DNN) processes these inputs to detect students’ physical and affective states, while a reinforcement learning (RL) algorithm dynamically generates individualised educational recommendations. A Proof-of-Authority (PoA) blockchain ensures secure, immutable, and transparent data management. Preliminary evaluations in simulated smart classrooms demonstrate significant improvements: the DNN achieves a 94.2% F1-score in state recognition, the RL module reduces critical event response latency, and energy efficiency improves by 23.5% compared to conventional baselines. Notably, intervention groups exhibit a 156% improvement in quiz scores over control groups. Compared to existing solutions, SHARP uniquely integrates multi-sensor physiological monitoring, real-time AI-based personalization, and blockchain-secured data governance in a unified framework. This results in superior accuracy, higher energy efficiency, and enhanced data integrity compared to prior IoT-based educational platforms. By combining intelligent sensing, adaptive analytics, and secure storage, SHARP offers a scalable and privacy-preserving solution for next-generation smart education. Full article
(This article belongs to the Special Issue Sensor-Based Recommender System for Smart Education and Smart Living)
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20 pages, 2437 KiB  
Article
A Skill-Inspired Adaptive Fuzzy Control Framework for Symmetric Gait Tracking with Sparse Sensor Fusion in Lower-Limb Exoskeletons
by Loqmane Bencharif, Abderahim Ibset, Hanbing Liu, Wen Qi, Hang Su and Samer Alfayad
Symmetry 2025, 17(8), 1265; https://doi.org/10.3390/sym17081265 - 7 Aug 2025
Viewed by 280
Abstract
This paper presents a real-time framework for bilateral gait reconstruction and adaptive joint control using sparse inertial sensing. The system estimates full lower-limb motion from a single-side inertial measurement unit (IMU) by applying a pipeline that includes signal smoothing, temporal alignment via Dynamic [...] Read more.
This paper presents a real-time framework for bilateral gait reconstruction and adaptive joint control using sparse inertial sensing. The system estimates full lower-limb motion from a single-side inertial measurement unit (IMU) by applying a pipeline that includes signal smoothing, temporal alignment via Dynamic Time Warping (DTW), and motion modeling using Gaussian Mixture Models with Regression (GMM-GMR). Contralateral leg trajectories are inferred using both ideal and adaptive symmetry-based models to capture inter-limb variations. The reconstructed motion serves as reference input for joint-level control. A classical Proportional–Integral–Derivative (PID) controller is first evaluated, demonstrating satisfactory results under simplified dynamics but notable performance loss when virtual stiffness and gravity compensation are introduced. To address this, an adaptive fuzzy PID controller is implemented, which dynamically adjusts control gains based on real-time tracking error through a fuzzy inference system. This approach enhances control stability and motion fidelity under varying conditions. The combined estimation and control framework enables accurate bilateral gait tracking and smooth joint control using minimal sensing, offering a practical solution for wearable robotic systems such as exoskeletons or smart prosthetics. Full article
(This article belongs to the Special Issue Symmetry/Asymmetry in Fuzzy Control)
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12 pages, 5474 KiB  
Article
Flexible Sensor with Material–Microstructure Synergistic Optimization for Wearable Physiological Monitoring
by Yaojia Mou, Cong Wang, Xiaohu Jiang, Jingxiang Wang, Changchao Zhang, Linpeng Liu and Ji’an Duan
Materials 2025, 18(15), 3707; https://doi.org/10.3390/ma18153707 - 7 Aug 2025
Viewed by 418
Abstract
Flexible sensors have emerged as essential components in next-generation technologies such as wearable electronics, smart healthcare, soft robotics, and human–machine interfaces, owing to their outstanding mechanical flexibility and multifunctional sensing capabilities. Despite significant advancements, challenges such as the trade-off between sensitivity and detection [...] Read more.
Flexible sensors have emerged as essential components in next-generation technologies such as wearable electronics, smart healthcare, soft robotics, and human–machine interfaces, owing to their outstanding mechanical flexibility and multifunctional sensing capabilities. Despite significant advancements, challenges such as the trade-off between sensitivity and detection range, and poor signal stability under cyclic deformation remain unresolved. To overcome the aforementioned limitations, this work introduces a high-performance soft sensor featuring a dual-layered electrode system, comprising silver nanoparticles (AgNPs) and a composite of multi-walled carbon nanotubes (MWCNTs) with carbon black (CB), coupled with a laser-engraved crack-gradient microstructure. This structural strategy facilitates progressive crack formation under applied strain, thereby achieving enhanced sensitivity (1.56 kPa−1), broad operational bandwidth (50–600 Hz), fine frequency resolution (0.5 Hz), and a rapid signal response. The synergistic structure also improves signal repeatability, durability, and noise immunity. The sensor demonstrates strong applicability in health monitoring, motion tracking, and intelligent interfaces, offering a promising pathway for reliable, multifunctional sensing in wearable health monitoring, motion tracking, and soft robotic systems. Full article
(This article belongs to the Special Issue Advanced Materials for Flexible Sensing Applications and Electronics)
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32 pages, 1435 KiB  
Review
Smart Safety Helmets with Integrated Vision Systems for Industrial Infrastructure Inspection: A Comprehensive Review of VSLAM-Enabled Technologies
by Emmanuel A. Merchán-Cruz, Samuel Moveh, Oleksandr Pasha, Reinis Tocelovskis, Alexander Grakovski, Alexander Krainyukov, Nikita Ostrovenecs, Ivans Gercevs and Vladimirs Petrovs
Sensors 2025, 25(15), 4834; https://doi.org/10.3390/s25154834 - 6 Aug 2025
Viewed by 385
Abstract
Smart safety helmets equipped with vision systems are emerging as powerful tools for industrial infrastructure inspection. This paper presents a comprehensive state-of-the-art review of such VSLAM-enabled (Visual Simultaneous Localization and Mapping) helmets. We surveyed the evolution from basic helmet cameras to intelligent, sensor-fused [...] Read more.
Smart safety helmets equipped with vision systems are emerging as powerful tools for industrial infrastructure inspection. This paper presents a comprehensive state-of-the-art review of such VSLAM-enabled (Visual Simultaneous Localization and Mapping) helmets. We surveyed the evolution from basic helmet cameras to intelligent, sensor-fused inspection platforms, highlighting how modern helmets leverage real-time visual SLAM algorithms to map environments and assist inspectors. A systematic literature search was conducted targeting high-impact journals, patents, and industry reports. We classify helmet-integrated camera systems into monocular, stereo, and omnidirectional types and compare their capabilities for infrastructure inspection. We examine core VSLAM algorithms (feature-based, direct, hybrid, and deep-learning-enhanced) and discuss their adaptation to wearable platforms. Multi-sensor fusion approaches integrating inertial, LiDAR, and GNSS data are reviewed, along with edge/cloud processing architectures enabling real-time performance. This paper compiles numerous industrial use cases, from bridges and tunnels to plants and power facilities, demonstrating significant improvements in inspection efficiency, data quality, and worker safety. Key challenges are analyzed, including technical hurdles (battery life, processing limits, and harsh environments), human factors (ergonomics, training, and cognitive load), and regulatory issues (safety certification and data privacy). We also identify emerging trends, such as semantic SLAM, AI-driven defect recognition, hardware miniaturization, and collaborative multi-helmet systems. This review finds that VSLAM-equipped smart helmets offer a transformative approach to infrastructure inspection, enabling real-time mapping, augmented awareness, and safer workflows. We conclude by highlighting current research gaps, notably in standardizing systems and integrating with asset management, and provide recommendations for industry adoption and future research directions. Full article
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19 pages, 487 KiB  
Review
Smart Clothing and Medical Imaging Innovations for Real-Time Monitoring and Early Detection of Stroke: Bridging Technology and Patient Care
by David Sipos, Kata Vészi, Bence Bogár, Dániel Pető, Gábor Füredi, József Betlehem and Attila András Pandur
Diagnostics 2025, 15(15), 1970; https://doi.org/10.3390/diagnostics15151970 - 6 Aug 2025
Viewed by 369
Abstract
Stroke is a significant global health concern characterized by the abrupt disruption of cerebral blood flow, leading to neurological impairment. Accurate and timely diagnosis—enabled by imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI)—is essential for differentiating stroke types and [...] Read more.
Stroke is a significant global health concern characterized by the abrupt disruption of cerebral blood flow, leading to neurological impairment. Accurate and timely diagnosis—enabled by imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI)—is essential for differentiating stroke types and initiating interventions like thrombolysis, thrombectomy, or surgical management. In parallel, recent advancements in wearable technology, particularly smart clothing, offer new opportunities for stroke prevention, real-time monitoring, and rehabilitation. These garments integrate various sensors, including electrocardiogram (ECG) electrodes, electroencephalography (EEG) caps, electromyography (EMG) sensors, and motion or pressure sensors, to continuously track physiological and functional parameters. For example, ECG shirts monitor cardiac rhythm to detect atrial fibrillation, smart socks assess gait asymmetry for early mobility decline, and EEG caps provide data on neurocognitive recovery during rehabilitation. These technologies support personalized care across the stroke continuum, from early risk detection and acute event monitoring to long-term recovery. Integration with AI-driven analytics further enhances diagnostic accuracy and therapy optimization. This narrative review explores the application of smart clothing in conjunction with traditional imaging to improve stroke management and patient outcomes through a more proactive, connected, and patient-centered approach. Full article
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46 pages, 4006 KiB  
Review
Solvent-Driven Electroless Nickel Coatings on Polymers: Interface Engineering, Microstructure, and Applications
by Chenyao Wang, Heng Zhai, David Lewis, Hugh Gong, Xuqing Liu and Anura Fernando
Coatings 2025, 15(8), 898; https://doi.org/10.3390/coatings15080898 - 1 Aug 2025
Viewed by 456
Abstract
Electroless nickel deposition (ELD) is an autocatalytic technique extensively used to impart conductive, protective, and mechanical functionalities to inherently non-conductive synthetic substrates. This review systematically explores the fundamental mechanisms of electroless nickel deposition, emphasising recent advancements in surface activation methods, solvent systems, and [...] Read more.
Electroless nickel deposition (ELD) is an autocatalytic technique extensively used to impart conductive, protective, and mechanical functionalities to inherently non-conductive synthetic substrates. This review systematically explores the fundamental mechanisms of electroless nickel deposition, emphasising recent advancements in surface activation methods, solvent systems, and microstructural control. Critical analysis reveals that bio-inspired activation methods, such as polydopamine (PDA) and tannic acid (TA), significantly enhance coating adhesion and durability compared to traditional chemical etching and plasma treatments. Additionally, solvent engineering, particularly using polar aprotic solvents like dimethyl sulfoxide (DMSO) and ethanol-based systems, emerges as a key strategy for achieving uniform, dense, and flexible coatings, overcoming limitations associated with traditional aqueous baths. The review also highlights that microstructural tailoring, specifically the development of amorphous-nanocrystalline hybrid nickel coatings, effectively balances mechanical robustness (hardness exceeding 800 HV), flexibility, and corrosion resistance, making these coatings particularly suitable for wearable electronic textiles and smart materials. Furthermore, commercial examples demonstrate the real-world applicability and market readiness of nickel-coated synthetic fibres. Despite significant progress, persistent challenges remain, including reliable long-term adhesion, internal stress management, and environmental sustainability. Future research should prioritise environmentally benign plating baths, standardised surface activation protocols, and scalable deposition processes to fully realise the industrial potential of electroless nickel coatings. Full article
(This article belongs to the Section Surface Characterization, Deposition and Modification)
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36 pages, 2671 KiB  
Article
DIKWP-Driven Artificial Consciousness for IoT-Enabled Smart Healthcare Systems
by Yucong Duan and Zhendong Guo
Appl. Sci. 2025, 15(15), 8508; https://doi.org/10.3390/app15158508 - 31 Jul 2025
Viewed by 274
Abstract
This study presents a DIKWP-driven artificial consciousness framework for IoT-enabled smart healthcare, integrating a Data–Information–Knowledge–Wisdom–Purpose (DIKWP) cognitive architecture with a software-defined IoT infrastructure. The proposed system deploys DIKWP agents at edge and cloud nodes to transform raw sensor data into high-level knowledge and [...] Read more.
This study presents a DIKWP-driven artificial consciousness framework for IoT-enabled smart healthcare, integrating a Data–Information–Knowledge–Wisdom–Purpose (DIKWP) cognitive architecture with a software-defined IoT infrastructure. The proposed system deploys DIKWP agents at edge and cloud nodes to transform raw sensor data into high-level knowledge and purpose-driven actions. This is achieved through a structured DIKWP pipeline—from data acquisition and information processing to knowledge extraction, wisdom inference, and purpose-driven decision-making—that enables semantic reasoning, adaptive goal-driven responses, and privacy-preserving decision-making in healthcare environments. The architecture integrates wearable sensors, edge computing nodes, and cloud services to enable dynamic task orchestration and secure data fusion. For evaluation, a smart healthcare scenario for early anomaly detection (e.g., arrhythmia and fever) was implemented using wearable devices with coordinated edge–cloud analytics. Simulated experiments on synthetic vital sign datasets achieved approximately 98% anomaly detection accuracy and up to 90% reduction in communication overhead compared to cloud-centric solutions. Results also demonstrate enhanced explainability via traceable decisions across DIKWP layers and robust performance under intermittent connectivity. These findings indicate that the DIKWP-driven approach can significantly advance IoT-based healthcare by providing secure, explainable, and adaptive services aligned with clinical objectives and patient-centric care. Full article
(This article belongs to the Special Issue IoT in Smart Cities and Homes, 2nd Edition)
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40 pages, 3463 KiB  
Review
Machine Learning-Powered Smart Healthcare Systems in the Era of Big Data: Applications, Diagnostic Insights, Challenges, and Ethical Implications
by Sita Rani, Raman Kumar, B. S. Panda, Rajender Kumar, Nafaa Farhan Muften, Mayada Ahmed Abass and Jasmina Lozanović
Diagnostics 2025, 15(15), 1914; https://doi.org/10.3390/diagnostics15151914 - 30 Jul 2025
Viewed by 725
Abstract
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, [...] Read more.
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, cross-domain ML applications, and a critical discussion on ethical integration in smart diagnostics. The review focuses on the role of big data analysis and ML towards better diagnosis, improved efficiency of operations, and individualized care for patients. It explores the principal challenges of data heterogeneity, privacy, computational complexity, and advanced methods such as federated learning (FL) and edge computing. Applications in real-world settings, such as disease prediction, medical imaging, drug discovery, and remote monitoring, illustrate how ML methods, such as deep learning (DL) and natural language processing (NLP), enhance clinical decision-making. A comparison of ML models highlights their value in dealing with large and heterogeneous healthcare datasets. In addition, the use of nascent technologies such as wearables and Internet of Medical Things (IoMT) is examined for their role in supporting real-time data-driven delivery of healthcare. The paper emphasizes the pragmatic application of intelligent systems by highlighting case studies that reflect up to 95% diagnostic accuracy and cost savings. The review ends with future directions that seek to develop scalable, ethical, and interpretable AI-powered healthcare systems. It bridges the gap between ML algorithms and smart diagnostics, offering critical perspectives for clinicians, data scientists, and policymakers. Full article
(This article belongs to the Special Issue Machine-Learning-Based Disease Diagnosis and Prediction)
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21 pages, 3471 KiB  
Review
Nanomedicine: The Effective Role of Nanomaterials in Healthcare from Diagnosis to Therapy
by Raisa Nazir Ahmed Kazi, Ibrahim W. Hasani, Doaa S. R. Khafaga, Samer Kabba, Mohd Farhan, Mohammad Aatif, Ghazala Muteeb and Yosri A. Fahim
Pharmaceutics 2025, 17(8), 987; https://doi.org/10.3390/pharmaceutics17080987 - 30 Jul 2025
Viewed by 328
Abstract
Nanotechnology is revolutionizing medicine by enabling highly precise diagnostics, targeted therapies, and personalized healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control. Engineered nanoparticles (NPs), such as liposomes, polymeric carriers, and carbon-based [...] Read more.
Nanotechnology is revolutionizing medicine by enabling highly precise diagnostics, targeted therapies, and personalized healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control. Engineered nanoparticles (NPs), such as liposomes, polymeric carriers, and carbon-based nanomaterials, enhance drug solubility, protect therapeutic agents from degradation, and enable site-specific delivery, thereby reducing toxicity to healthy tissues. In diagnostics, nanosensors and contrast agents provide ultra-sensitive detection of biomarkers, supporting early diagnosis and real-time monitoring. Nanotechnology also contributes to regenerative medicine, antimicrobial therapies, wearable devices, and theranostics, which integrate treatment and diagnosis into unified systems. Advanced innovations such as nanobots and smart nanosystems further extend these capabilities, enabling responsive drug delivery and minimally invasive interventions. Despite its immense potential, nanomedicine faces challenges, including biocompatibility, environmental safety, manufacturing scalability, and regulatory oversight. Addressing these issues is essential for clinical translation and public acceptance. In summary, nanotechnology offers transformative tools that are reshaping medical diagnostics, therapeutics, and disease prevention. Through continued research and interdisciplinary collaboration, it holds the potential to significantly enhance treatment outcomes, reduce healthcare costs, and usher in a new era of precise and personalized medicine. Full article
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12 pages, 1492 KiB  
Article
User Experiences of the Cue2walk Smart Cueing Device for Freezing of Gait in People with Parkinson’s Disease
by Matthijs van der Laan, Marc B. Rietberg, Martijn van der Ent, Floor Waardenburg, Vincent de Groot, Jorik Nonnekes and Erwin E. H. van Wegen
Sensors 2025, 25(15), 4702; https://doi.org/10.3390/s25154702 - 30 Jul 2025
Viewed by 478
Abstract
Freezing of gait (FoG) impairs mobility and daily functioning and increases the risk of falls, leading to a reduced quality of life (QoL) in people with Parkinson’s disease (PD). The Cue2walk, a wearable smart cueing device, can detect FoG and hereupon provides rhythmic [...] Read more.
Freezing of gait (FoG) impairs mobility and daily functioning and increases the risk of falls, leading to a reduced quality of life (QoL) in people with Parkinson’s disease (PD). The Cue2walk, a wearable smart cueing device, can detect FoG and hereupon provides rhythmic cues to help people with PD manage FoG in daily life. This study investigated the user experiences and device usage of the Cue2walk, and its impact on health-related QoL, FoG and daily activities. Twenty-five users of the Cue2walk were invited to fill out an online survey, which included a modified version of the EQ-5D-5L, tailored to the use of the Cue2walk, and its scale for health-related QoL, three FoG-related questions, and a question about customer satisfaction. Sixteen users of the Cue2walk completed the survey. Average device usage per day was 9 h (SD 4). Health-related QoL significantly increased from 5.2/10 (SD 1.3) to 6.2/10 (SD 1.3) (p = 0.005), with a large effect size (Cohen’s d = 0.83). A total of 13/16 respondents reported a positive effect on FoG duration, 12/16 on falls, and 10/16 on daily activities and self-confidence. Customer satisfaction was 7.8/10 (SD 1.7). This pilot study showed that Cue2walk usage per day is high and that 15/16 respondents experienced a variety of positive effects since using the device. To validate these findings, future studies should include a larger sample size and a more extensive set of questionnaires and physical measurements monitored over time. Full article
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20 pages, 16450 KiB  
Article
A Smart Textile-Based Tactile Sensing System for Multi-Channel Sign Language Recognition
by Keran Chen, Longnan Li, Qinyao Peng, Mengyuan He, Liyun Ma, Xinxin Li and Zhenyu Lu
Sensors 2025, 25(15), 4602; https://doi.org/10.3390/s25154602 - 25 Jul 2025
Viewed by 371
Abstract
Sign language recognition plays a crucial role in enabling communication for deaf individuals, yet current methods face limitations such as sensitivity to lighting conditions, occlusions, and lack of adaptability in diverse environments. This study presents a wearable multi-channel tactile sensing system based on [...] Read more.
Sign language recognition plays a crucial role in enabling communication for deaf individuals, yet current methods face limitations such as sensitivity to lighting conditions, occlusions, and lack of adaptability in diverse environments. This study presents a wearable multi-channel tactile sensing system based on smart textiles, designed to capture subtle wrist and finger motions for static sign language recognition. The system leverages triboelectric yarns sewn into gloves and sleeves to construct a skin-conformal tactile sensor array, capable of detecting biomechanical interactions through contact and deformation. Unlike vision-based approaches, the proposed sensor platform operates independently of environmental lighting or occlusions, offering reliable performance in diverse conditions. Experimental validation on American Sign Language letter gestures demonstrates that the proposed system achieves high signal clarity after customized filtering, leading to a classification accuracy of 94.66%. Experimental results show effective recognition of complex gestures, highlighting the system’s potential for broader applications in human-computer interaction. Full article
(This article belongs to the Special Issue Advanced Tactile Sensors: Design and Applications)
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