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Search Results (310)

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Keywords = sleep scheduling

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33 pages, 4978 KB  
Article
Smart Enforcement of Disability Parking: A Drone-Based License Plate Recognition and Staged Optimization Framework
by Hanaa ZainEldin, Tamer Ahmed Farrag, Shymaa G. Eladl, Malik Almaliki, Mahmoud Badawy and Mostafa A. Elhosseini
Urban Sci. 2026, 10(4), 212; https://doi.org/10.3390/urbansci10040212 - 15 Apr 2026
Viewed by 112
Abstract
Unauthorized occupation of parking spaces designated for individuals with disabilities remains a persistent challenge in urban environments, limiting accessibility and inclusive mobility. This paper proposes an integrated UAV-assisted enforcement framework that combines drone-based imaging, onboard license plate recognition (LPR), IoT connectivity, and a [...] Read more.
Unauthorized occupation of parking spaces designated for individuals with disabilities remains a persistent challenge in urban environments, limiting accessibility and inclusive mobility. This paper proposes an integrated UAV-assisted enforcement framework that combines drone-based imaging, onboard license plate recognition (LPR), IoT connectivity, and a staged optimization strategy for energy-aware surveillance. The framework employs a two-phase approach: first, it derives energy-efficient UAV activation patterns via sleep–active scheduling, followed by coverage maximization under energy constraints. The inherently multi-objective problem—balancing energy consumption, coverage, and redundancy—is addressed via a weighted-aggregation formulation, enabling efficient optimization with classical metaheuristic algorithms. Seven algorithms—Genetic Algorithm (GA), Particle Swarm Optimization (PSO), Simulated Annealing (SA), Ant Colony Optimization (ACO), Differential Evolution (DE), Artificial Bee Colony (ABC), and a Greedy baseline—are implemented in both conventional and staged variants to enable comprehensive evaluation. Experimental results demonstrate 32–45% reductions in energy consumption, over 95% coverage effectiveness, and 50–60% faster convergence compared to single-phase approaches, with all improvements statistically significant (p < 0.001). The proposed framework provides a scalable, practically deployable solution for intelligent enforcement of disability parking regulations while also enabling energy-efficient UAV coordination in smart urban monitoring systems. Full article
12 pages, 527 KB  
Article
The Effect of Intravenous Lidocaine Treatment on Sleep and Quality of Life in Fibromyalgia: An Observational Study
by Halil Ibrahim Altun and Fatma Aysen Eren
J. Clin. Med. 2026, 15(8), 2887; https://doi.org/10.3390/jcm15082887 - 10 Apr 2026
Viewed by 307
Abstract
Background/Objectives: Fibromyalgia is a painful syndrome with biopsychosocial components that predominantly affects middle-aged women. This study aimed to evaluate changes in sleep quality and quality of life following intravenous (IV) lidocaine treatment in patients with fibromyalgia (FM). Methods: This retrospective observational [...] Read more.
Background/Objectives: Fibromyalgia is a painful syndrome with biopsychosocial components that predominantly affects middle-aged women. This study aimed to evaluate changes in sleep quality and quality of life following intravenous (IV) lidocaine treatment in patients with fibromyalgia (FM). Methods: This retrospective observational study included patients diagnosed with fibromyalgia who underwent intravenous lidocaine treatment at a tertiary pain clinic between June 2023 and June 2024 and had a Pittsburgh Sleep Quality Index (PSQI) score > 5. The patients’ demographic data, Fibromyalgia Impact Questionnaire (FIQ) scores at baseline and at 1 and 3 months post-treatment, Numerical Rating Scale (NRS-11) scores, Short Form-12 (SF-12) mental and physical component scores (MCS-12, PCS-12), and PSQI scores were recorded. Results: Overall, 51 patients were included. 92.2% of the patients were women, with a mean age of 41.6 ± 9.5 years. Statistically significant reductions in NRS-11, FIQ, and PSQI scores and increases in SF-12 component scores were observed at 1 and 3 months compared with baseline (p < 0.001). Negative correlations were found between NRS-11 and PCS-12 and MCS-12, and a positive correlation was found between FIQ and PSQI. Sleep quality showed a marked improvement at 1 month; however, attenuation of this benefit was observed at the 3-month follow-up. Conclusions: Sleep quality appeared to be associated with short-term functional outcomes, whereas pain intensity was associated with mid-term clinical status in patients with fibromyalgia. Prospective randomized controlled trials are required to confirm these findings and to determine optimal dosing and treatment schedules. Full article
(This article belongs to the Special Issue Advances in Chronic Pain Research and Therapy)
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13 pages, 282 KB  
Opinion
Sleepless in Society: Introducing the Concept of Public Sleep
by Tony J. Cunningham, Shengzi Zeng and Seo Ho Song
Clocks & Sleep 2026, 8(2), 18; https://doi.org/10.3390/clockssleep8020018 - 9 Apr 2026
Viewed by 456
Abstract
Major social, cultural, and sociopolitical events routinely disrupt daily life, yet their effects on sleep are rarely conceptualized at the population level beyond anecdotal sharing. The purpose of this Opinion piece is to initiate a preliminary discussion of “public sleep” as a novel [...] Read more.
Major social, cultural, and sociopolitical events routinely disrupt daily life, yet their effects on sleep are rarely conceptualized at the population level beyond anecdotal sharing. The purpose of this Opinion piece is to initiate a preliminary discussion of “public sleep” as a novel construct describing systematic, event-related changes in sleep timing, duration, and quality that emerge coherently within communities in response to shared social experiences. Drawing on similarities with the well-established concept of public mood, we posit that sleep can be shaped by social environments in which shared attention, emotional climate, and coordinated schedules exert systematic influence. In support of this claim, we describe preliminary evidence from diverse domains demonstrating population-level sleep disruption following major events, including the transition to Daylight Saving Time, national elections, prolonged crises such as the COVID-19 pandemic and armed conflicts, and highly salient cultural activities such as major sporting events. These reports from disparate fields provide an initial indication that public sleep disruptions can be acute or prolonged, geographically localized or global, and may be shaped by the duration, emotional intensity, and perceived importance of the associated event. We further highlight the potential public health, safety, social, and economic consequences of collective sleep loss, underscoring its relevance beyond individual well-being. Finally, we outline key directions for future research, emphasizing the need for systematic reviews, mechanistic studies, longitudinal designs, and policy-relevant recommendations. Recognizing public sleep as a measurable population phenomenon would provide a foundation for anticipating, monitoring, and mitigating sleep disruption during periods of collective strain, with implications for both individual health and societal resilience. Full article
(This article belongs to the Section Disorders)
33 pages, 2798 KB  
Review
Fatigue and Sleep Deprivation in the Offshore Oil and Gas Industry: A Systematic Review of Health, Performance and Safety Implications
by Werneck Ubiratan Felipe Santos, Carina Mariane Stolz and Mayara Amario
Safety 2026, 12(2), 45; https://doi.org/10.3390/safety12020045 - 3 Apr 2026
Viewed by 496
Abstract
Working conditions in the offshore oil and gas industry can expose workers to fatigue and sleep deprivation due to extended working hours, irregular shift schedules, and highly complex operational environments. This study aimed to conduct a systematic review of scientific literature on fatigue [...] Read more.
Working conditions in the offshore oil and gas industry can expose workers to fatigue and sleep deprivation due to extended working hours, irregular shift schedules, and highly complex operational environments. This study aimed to conduct a systematic review of scientific literature on fatigue and sleep deprivation in the offshore oil and gas sector and their implications for health, performance, and safety. The systematic review was conducted in accordance with the PRISMA 2020 guidelines and included primary studies published between 2015 and 2025, retrieved from the Scopus, Web of Science, ScienceDirect, PubMed, and Embase databases. Following the eligibility assessment, fifty studies were included in the final analysis. The selected studies were classified according to their level of direct relevance to offshore oil and gas operations, distinguishing evidence derived from offshore platforms from that obtained in analogous operational settings. The findings demonstrate consistent associations between fatigue and chronic sleep deprivation and adverse occupational health outcomes. Regulatory gaps were also identified when comparing different international approaches to fatigue risk management in the offshore sector. Overall, the results underscore the need for integrated fatigue management strategies aligned with best international practices to enhance health and safety in offshore operations. Full article
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13 pages, 245 KB  
Article
Sleep Quality and Associated Factors Among Medical Students in Tropical China: A Cross-Sectional Study in Hainan Province
by Li-Qin Fu, Zhao-Xin Wang, Xin-Yi Li, Di-Er Cheng, Zhen Zhou and Hou-Qian Shan
Healthcare 2026, 14(7), 908; https://doi.org/10.3390/healthcare14070908 - 1 Apr 2026
Viewed by 342
Abstract
Background: Sleep problems are prevalent among student populations worldwide. Medical students, facing heavy academic workloads and intense pressure, are particularly susceptible to sleep disorders. While sleep quality among Chinese university students has been consistently declining, research focusing on medical students in tropical island [...] Read more.
Background: Sleep problems are prevalent among student populations worldwide. Medical students, facing heavy academic workloads and intense pressure, are particularly susceptible to sleep disorders. While sleep quality among Chinese university students has been consistently declining, research focusing on medical students in tropical island provinces like Hainan remains insufficient. This study aims to address this geographical gap by analyzing the sleep quality status and influencing factors among medical students in Hainan Province. Objective: To investigate the current status of sleep quality and its associated factors among medical students in Hainan Province, providing a scientific basis for developing targeted interventions. Methods: A cross-sectional survey was conducted in April 2024 using purposive sampling to recruit undergraduate students from a medical university in Hainan. The Self-Rating Scale of Sleep (SRSS) developed by Li Jianming was administered, and 551 valid questionnaires were collected anonymously. Data were analyzed using univariate analysis and pairwise comparisons to assess sleep quality and associated factors, with demographic variables as independent variables. Results: Among participants, 40.1% reported sleep problems (31.2% mild, 8.2% moderate, 0.7% severe). The mean total SRSS score was 21.78 ± 5.73. Compared to the national norm, medical students showed significantly higher scores in sleep quality, insufficient arousal, and post-insomnia responses (p < 0.05). Academic major was identified as a significant influencing factor (p = 0.012), with clinical medicine students demonstrating significantly poorer sleep quality than health management majors (p = 0.010). No significant differences were found for gender or academic year. Conclusions: Sleep problems are prominent among medical students in Hainan, with clinical medicine students at higher risk due to academic and professional pressures. Recommendations include optimizing curriculum schedules, strengthening psychological support systems, and developing targeted interventions for clinical majors. Full article
15 pages, 2649 KB  
Article
Pediatric Adenotonsillectomy over 20 Years in a High-Volume Italian Centre: Positive Outcomes with Low Complications—The Sassuolo Hospital Experience
by Gennaro Confuorto, Renato Baldi, Elisa Cigarini, Giorgio Di Lorenzo, Silvia Menabue, Federico Spagnolo, Margherita Trani, Massimo Zanni, Livio Presutti, Daniele Marchioni and Paolo Gambelli
Pediatr. Rep. 2026, 18(2), 45; https://doi.org/10.3390/pediatric18020045 - 23 Mar 2026
Viewed by 303
Abstract
Background: Pediatric adenotonsillectomy is commonly performed for infectious and obstructive indications, but postoperative hemorrhage remains a concern. This study describes outcomes from a high-volume territorial network in southern Modena province, Italy. Methods: Retrospective observational study of 10,753 pediatric patients (aged 3–18 years) undergoing [...] Read more.
Background: Pediatric adenotonsillectomy is commonly performed for infectious and obstructive indications, but postoperative hemorrhage remains a concern. This study describes outcomes from a high-volume territorial network in southern Modena province, Italy. Methods: Retrospective observational study of 10,753 pediatric patients (aged 3–18 years) undergoing adenotonsillectomy at Sassuolo Hospital and affiliates (Vignola, Pavullo) from 2005 to 2024. Indications included recurrent tonsillitis (Paradise criteria), obstructive sleep apnea (OSA) (polysomnography-confirmed or clinical), and recurrent otitis media or otitis media with effusion (OME). Surgical techniques included curettage adenoidectomy and Colorado microdissection needle tonsillectomy. Our institutional postoperative care protocol included analgesics, oral hydration, soft diet, antibiotics (amoxicillin) and scheduled follow-up; however, no analysis regarding this protocol was intended to demonstrate correlations with study outcomes. Primary outcomes were postoperative hemorrhage (overall and requiring revision), stratified by indication, age, and technique, and contextualized against ranges reported in large published cohorts (qualitative, exploratory comparison). Secondary outcomes included pain (VAS scores), infection rates, and tissue regrowth. Data completeness was verified via electronic records (95.6%). Statistical analyses used descriptive statistics with 95% confidence intervals (95% CI) and inferential tests for within-cohort comparisons (χ2 tests, Fisher’s exact test, and t-tests where appropriate). Results: A total of 10,753 procedures were analyzed (4325 tonsillectomies, 3942 adenotonsillectomies, 2486 adenoidectomies). Postoperative hemorrhage occurred in 202 patients (1.88%; 95% CI 1.64–2.15%); surgical revision was required in 75 (0.70%; 95% CI 0.56–0.87%), with multifactorial stratification showing higher risk for infectious indications (OR 1.41 vs. OSA), younger age < 5 years (OR 2.1), and tonsillectomy origin (OR 8.25 vs. adenoidectomy); all rates are at the lower end of literature ranges (2–5% and 0.9–2.5%, respectively), in line with large published cohorts, although these comparisons are qualitative and exploratory. Mean VAS pain scores decreased from 3.2 (day 1) to 1.1 (day 7). No significant infections occurred; tissue regrowth rates aligned with the literature (adenoidal 6–26%, tonsillar 5–10%). Conclusions: Sassuolo Hospital’s experience highlights favorable postoperative outcomes and low complication rates in adenotonsillar surgery. Limitations include the retrospective design, potential selection bias and long period evaluation. Prospective studies are needed to confirm these findings. Full article
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42 pages, 880 KB  
Systematic Review
Scenario Parameters for Fatigue Induction in Truck-Driving Simulators: A Systematic Review of Experimental Designs
by Tiago Fonseca and Sara Ferreira
Appl. Sci. 2026, 16(6), 3057; https://doi.org/10.3390/app16063057 - 22 Mar 2026
Viewed by 271
Abstract
Driving simulators offer a safe and controlled way to study fatigue in truck drivers, but variation in scenario design and incomplete reporting limit reproducibility and cross-study comparison. This systematic review synthesized scenario parameters used in truck-driving simulators to induce fatigue-related reductions in alertness [...] Read more.
Driving simulators offer a safe and controlled way to study fatigue in truck drivers, but variation in scenario design and incomplete reporting limit reproducibility and cross-study comparison. This systematic review synthesized scenario parameters used in truck-driving simulators to induce fatigue-related reductions in alertness and identified recurring protocol patterns associated with interpretable fatigue-related change. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines and a prospectively registered protocol (PROSPERO CRD420261302272), systematic searches were conducted in February 2026 in Scopus, Web of Science, IEEE Xplore, PubMed, and ScienceDirect. Peer-reviewed original studies published in English were eligible if they involved truck drivers, used a driving simulator, reported fatigue-relevant scenario parameters, and measured at least one fatigue-related outcome; no restriction was applied to publication year. Twenty-three studies comprising 419 participants met the eligibility criteria and were synthesized narratively. Risk of bias was appraised using an adapted 11-item checklist for driving simulator experiments, developed with the National Heart, Lung, and Blood Institute (NHLBI) quality assessment tools as a reference framework. Across the qualitative evidence base, fatigue-related change was reported more consistently in protocols combining sustained time on task with low-variability driving demands, typically implemented through monotonous road environments and reduced traffic complexity. Effects were more readily interpretable when sessions were scheduled at night or after work shifts and when outcomes were assessed repeatedly during the drive. However, incomplete control or reporting of baseline sleep pressure, stimulant intake, counterbalancing, familiarization, simulator sickness, and outlier handling limited causal interpretation and confidence in cross-study comparison. Overall, the evidence supports recurring design patterns rather than a single optimal protocol and highlights the need for standardized scenario descriptions and minimum reporting requirements. Full article
(This article belongs to the Section Transportation and Future Mobility)
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15 pages, 1098 KB  
Systematic Review
Shifts with Nights and Migraine Prevalence Among Nurses: A Systematic Review and Meta-Analysis
by Piedad Gómez-Torres, Azahara Ruger-Navarrete, Laura Lasso-Olayo, Isabel Blázquez-Ornat, David Peña-Otero and Sergio Galarreta-Aperte
Healthcare 2026, 14(6), 774; https://doi.org/10.3390/healthcare14060774 - 19 Mar 2026
Viewed by 374
Abstract
Background: Fixed night work and rotating schedules including nights may contribute to migraine via sleep disruption and circadian misalignment, but evidence is inconsistent and definitions vary. This systematic review and meta-analysis compared past-year migraine prevalence in nurses working night-inclusive schedules versus day-only [...] Read more.
Background: Fixed night work and rotating schedules including nights may contribute to migraine via sleep disruption and circadian misalignment, but evidence is inconsistent and definitions vary. This systematic review and meta-analysis compared past-year migraine prevalence in nurses working night-inclusive schedules versus day-only or non-night schedules. Methods: Following PRISMA 2020 and registered in PROSPERO (CRD420261304288), we searched PubMed, Scopus, Web of Science, CINAHL, and the Cochrane Library from inception to 3 February 2026 (English/Spanish). Observational studies in nurses (≥18 years) reporting past-year migraine prevalence by shift pattern were eligible. All included studies assessed past-year prevalence; pooled PRs reflect 1-year prevalence. Crude prevalence ratios (PRs) were calculated from contingency tables and pooled quantitatively. Risk of bias was assessed with the JBI prevalence checklist. Results: We identified 54 records; 4 studies were included (N = 3843) of which 3323 participants contributed to the comparative meta-analysis because complete disaggregated data were available to construct contingency tables. The pooled association between night-inclusive schedules and migraine prevalence was not statistically significant (PR = 0.95, 95% CI 0.82–1.10; I2 = 0%). Secondary intensity contrasts were inconclusive (high vs. low: PR = 1.24, 95% CI 0.46–3.36; high vs. zero nights: PR = 0.85, 95% CI 0.38–1.93). Conclusions: Current nurse-specific evidence does not show a statistically significant difference in migraine prevalence between night-inclusive and non-night schedules; however, the small evidence base and limited generalizability preclude firm conclusions. Future longitudinal studies are needed to clarify this association. Full article
(This article belongs to the Special Issue Innovative Approaches to Healthcare Worker Wellbeing)
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21 pages, 1805 KB  
Article
Searching for a Connection Between the Phenomenon of Transport Exclusion and the Presence of Gastroenterological Symptoms: A Survey of Secondary School Students in Poland
by Hubert Paweł Szyller, Agata Mytych, Gabriela Augustynowicz, Marta Dziedziak, Maria Lasocka, Mikołaj Michałek and Tomasz Pytrus
Nutrients 2026, 18(6), 949; https://doi.org/10.3390/nu18060949 - 17 Mar 2026
Viewed by 514
Abstract
Background: Transport exclusion and difficult access to educational institutions pose a significant problem for maintaining daily routines, sleep patterns and eating habits and are a potential cause of gastroenterological disorders. This study aims to demonstrate the possible associations between transport difficulties and selected [...] Read more.
Background: Transport exclusion and difficult access to educational institutions pose a significant problem for maintaining daily routines, sleep patterns and eating habits and are a potential cause of gastroenterological disorders. This study aims to demonstrate the possible associations between transport difficulties and selected gastrointestinal symptoms. Methods: A cross-sectional anonymous online survey was conducted among 650 students aged 15–20 years from urban and rural areas. Data on place of residence, commuting time, wake-up time, breakfast habits, and gastrointestinal symptoms were analyzed by chi-square tests, nonparametric methods, and correlation analyses. Results: The survey demonstrated the association between commutes to school and the occurrence of morning nausea, abdominal pain, and irregular meal patterns. Early wake-up times are also associated with the risk of symptoms. Transport-related factors, particularly long commuting times and early wake-up schedules, are associated with more irregular eating patterns and a higher prevalence of morning gastrointestinal symptoms in adolescents. Conclusions: Transport exclusion may represent an important, yet understudied, factor influencing adolescent health. Full article
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32 pages, 3714 KB  
Article
PSO-Based Dynamic RSU Role Assignment Framework for Scalable and Reliable Content Delivery in VANETs
by Yongje Shin, Hyunseok Choi, Youngju Nam and Euisin Lee
Sensors 2026, 26(5), 1555; https://doi.org/10.3390/s26051555 - 2 Mar 2026
Viewed by 306
Abstract
Vehicular Ad-hoc Networks (VANETs) must sustain heterogeneous real-time content services, yet static roadside-unit (RSU) roles lead to congestion, coverage voids, and inefficient content delivery under bursty, concurrent demand. To address this issue, we propose a PSO-Based dynamic RSU role assignment framework named PDRA [...] Read more.
Vehicular Ad-hoc Networks (VANETs) must sustain heterogeneous real-time content services, yet static roadside-unit (RSU) roles lead to congestion, coverage voids, and inefficient content delivery under bursty, concurrent demand. To address this issue, we propose a PSO-Based dynamic RSU role assignment framework named PDRA that dynamically adapts roles, coverage, and replication of RSU to current network conditions. A telemetry-based suitability estimator aggregates location, link stability, resource availability, traffic load, and content sensitivity at each RSU and feeds a Particle Swarm Optimization routine that assigns RSUs to Leader/Helper/Inactive roles while enforcing spatial separation between Leaders. An adaptive sectoring mechanism then resizes each cluster RSU’s communication scope—contracting under overload to protect local latency and expanding during slack to assist neighbors—thereby suppressing void areas and balancing service density. On top of the physical layer of RSUs, Leader RSUs cooperatively form a virtual Replication Layer that maintains global visibility of load and content locality to steer requests and replicate popular data near demand, reducing backhaul reliance. Finally, a load- and energy-aware reconfiguration policy orchestrates staged assist/offload, selective Helper activation, PSO-based Leader reassignment, and sleep scheduling for underutilized RSUs, preserving resilience and sustainability. NS-3 urban scenarios corroborate that PDRA improves packet delivery, lowers end-to-end delay, reduces backhaul traffic, and increases fairness over strong baselines. By jointly optimizing role assignment, coverage control, and replication, PDRA offers a scalable and robust solution for VANET content delivery under dynamic, multi-user conditions. Full article
(This article belongs to the Section Sensor Networks)
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27 pages, 4842 KB  
Article
Diurnal Regulation and Gene-Specific Vulnerability of Oxidative Alcohol-Metabolizing Enzymes to Circadian Disruption
by Yool Lee, Ali Keshavarzian and Byoung-Joon Song
Int. J. Mol. Sci. 2026, 27(4), 2041; https://doi.org/10.3390/ijms27042041 - 22 Feb 2026
Viewed by 878
Abstract
Oxidative alcohol metabolism in the liver relies on sequential enzymatic reactions involving alcohol dehydrogenase (ADH), cytochrome P450 2E1 (CYP2E1), and aldehyde dehydrogenase (ALDH) isozymes. However, the circadian regulation of these enzymes, their susceptibility to genetic, environmental, and metabolic disruption, and their functional implications [...] Read more.
Oxidative alcohol metabolism in the liver relies on sequential enzymatic reactions involving alcohol dehydrogenase (ADH), cytochrome P450 2E1 (CYP2E1), and aldehyde dehydrogenase (ALDH) isozymes. However, the circadian regulation of these enzymes, their susceptibility to genetic, environmental, and metabolic disruption, and their functional implications toward alcohol-mediated tissue injury remain incompletely defined. To address this gap, we performed a comprehensive integrative analysis of the publicly available circadian transcriptome datasets spanning genetic clock disruption, acute sleep deprivation, chronic high-fat diet feeding, and occupational shift work to systematically characterize the temporal regulation and disruption vulnerability of the major alcohol-metabolizing enzymes. Mouse tissue-cycling analyses revealed pronounced gene- and tissue-specific diurnal regulation, with Adh1 oscillating primarily in adipose tissues; Cyp2e1 and mitochondrial Aldh2 cycling broadly across kidney, aorta, lung, adrenal gland, and liver; and cytosolic Aldh1b1 being uniformly arrhythmic. In the liver, Cyp2e1 and Aldh2 exhibited robust ~24 h oscillations that peaked during the light/resting phase, while Adh1 showed inconsistent rhythmicity and Aldh1b1 remained arrhythmic. Notably, Cyp2e1 and Aldh2 rhythms persisted in Bmal1 knockout and Clock mutant livers under light–dark conditions, despite complete loss of core clock gene oscillations, yet were abolished in constant darkness, revealing that systemic zeitgeber cues can mask the loss of intrinsic clock function to maintain apparent rhythmicity in these metabolic genes. Systematic cross-paradigm comparison established a novel gene-specific vulnerability hierarchy. Aldh2 was found to be most disrupted by environmental and metabolic perturbations, with acute sleep deprivation eliminating its rhythmicity and temporal expression pattern and a Western-style high-fat diet inducing pronounced phase delays and rhythm loss relative to low-fat diet controls. Both disruptions paralleled alterations in hepatocyte nuclear factor 4α (Hnf4a), newly implicating HNF4α as a potential mediator of ALDH2 circadian instability. In humans, ALDH2 and CYP2E1 exhibited conserved but phase-inverted circadian rhythms across multiple tissues relative to mice, and, importantly, night-shift workers showed markedly dampened and phase-shifted ALDH2 rhythms in peripheral blood mononuclear cells, providing the molecular link between occupational circadian misalignment and impaired acetaldehyde detoxification. Collectively, our detailed and innovative analytical approach reveals gene- and tissue-specific circadian regulation of alcohol-metabolizing enzymes, identifies ALDH2 as uniquely vulnerable to circadian misalignment, underscores the importance of circadian timing for optimal hepatic detoxification and resistance to tissue injury, and suggests that monitoring circadian rhythms could help tailor individualized advice on alcohol consumption for shift workers and populations with irregular sleep schedules, informing precision medicine approaches for alcohol-related disorders. Full article
(This article belongs to the Special Issue Exploring the Impact of the Biological Clock on Health and Disease)
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18 pages, 483 KB  
Review
Circadian Rhythm and Sleep Disturbances in Young Adult Athletes: A Review About Risk Factors, Consequences, and Interventions
by Anne M. Fink and Michele Kerulis
Brain Sci. 2026, 16(2), 212; https://doi.org/10.3390/brainsci16020212 - 11 Feb 2026
Viewed by 1105
Abstract
Background/Objectives: College student athletes can experience sleep and circadian rhythm disturbances. Methods: A PRISMA-based systematic review about young adult athletes’ sleep and circadian rhythms was conducted, with 41 published studies analyzed. Results: Studies suggest that extending sleep duration could enhance [...] Read more.
Background/Objectives: College student athletes can experience sleep and circadian rhythm disturbances. Methods: A PRISMA-based systematic review about young adult athletes’ sleep and circadian rhythms was conducted, with 41 published studies analyzed. Results: Studies suggest that extending sleep duration could enhance athletic performance and support mental health. Risk factors for sleep and circadian rhythm disturbances include early morning practice sessions, late night games, jet lag, and female sex. Consequences of inadequate sleep include reduced reaction times and mental health problems, such as depressive symptoms and anxiety. Across the studies, numerous research design limitations reduced scientific rigor and hindered the ability to test hypotheses about sleep, circadian rhythms, athletic performance, and mental health outcomes. For example, most studies were underpowered due to small sample sizes and missing data. Many studies lacked randomization, control groups, and objective measures of sleep. Researchers commonly failed to control for variables that could confound results (e.g., caffeine, diet, and menstrual cycle hormones). Conclusions: Recommendations for future directions include conducting randomized clinical trials to test interventions related to sleep patterns, nutrition, light exposure, training schedules, and cognitive behavioral therapies to enhance sleep quality. Evidence-based education programs about healthy sleep are essential for coaches and athletes. Full article
(This article belongs to the Special Issue Relationships Between Disordered Sleep and Mental Health)
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13 pages, 14598 KB  
Article
CSL-YMS: Sensor-Fusion and Energy Efficient Task Scheduling
by Sunita Dahiya, Rashmi Chawla and Giancarlo Fortino
Appl. Sci. 2026, 16(4), 1732; https://doi.org/10.3390/app16041732 - 10 Feb 2026
Viewed by 370
Abstract
In many IIoT-based yard operations, accurately identifying the spatial position of containers is becoming increasingly relevant as operators try to automate stacking and retrieval processes by technologies like Container Spatial Localization (CSL). Despite this automation in IIoT, RTK-GPS–based container stacker positioning frequently lacks [...] Read more.
In many IIoT-based yard operations, accurately identifying the spatial position of containers is becoming increasingly relevant as operators try to automate stacking and retrieval processes by technologies like Container Spatial Localization (CSL). Despite this automation in IIoT, RTK-GPS–based container stacker positioning frequently lacks precision, which causes disruptions in stacking and reduces efficiency in space utilisation. Though it offers placement precision accurately up to 3 cm, this is still insufficient in high-volume Yard Management Systems (YMS). Consequently, this yields to variable container orientation, waste of usable space, increased man input is required in handling goods, and potential automated system failures. This research proposes a novel methodology that combines conventional RTK-GPS measurements with angular information captured from a BHI-260AP–based spreader sensor, allowing the system to correct container placement errors arising from orientation rather than only from positioning. In addition to the spatial positioning problem, we found that continuous IIoT operation raises concerns regarding energy use, particularly when micro-controllers remain active throughout the task cycle. As a solution, this integrates a dynamic task scheduling approach that puts the device in sleep modes whenever computation is not required. In our experiments, this strategy improved overall power efficiency by 34.44%, which makes long automated operation more practical. Full article
(This article belongs to the Section Transportation and Future Mobility)
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47 pages, 1185 KB  
Review
The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Improving Performance in Soccer Players—A Scoping Review
by James Chmiel and Donata Kurpas
J. Clin. Med. 2026, 15(3), 1281; https://doi.org/10.3390/jcm15031281 - 5 Feb 2026
Cited by 1 | Viewed by 790
Abstract
Background/Objectives: Transcranial direct current stimulation (tDCS) is increasingly used by athletes, yet sport-performance-enhancement findings are mixed and often small, with outcomes depending on stimulation target, timing, and task demands. Aim: This scoping review mapped and synthesized the soccer-specific trial evidence to identify (i) [...] Read more.
Background/Objectives: Transcranial direct current stimulation (tDCS) is increasingly used by athletes, yet sport-performance-enhancement findings are mixed and often small, with outcomes depending on stimulation target, timing, and task demands. Aim: This scoping review mapped and synthesized the soccer-specific trial evidence to identify (i) which tDCS targets and application schedules have been tested in soccer players, (ii) which soccer-relevant outcomes show the most consistent immediate (minutes–hours) or training-mediated benefits, and (iii) where evidence gaps persist. Methods: We conducted a scoping review of clinical trials in footballers, following review best-practice guidance (PRISMA-informed) and a preregistered protocol. Searches (August 2025) spanned PubMed/MEDLINE, ResearchGate, Google Scholar, and Cochrane, using combinations of “football/soccer” and “tDCS/transcranial direct current stimulation,” with inclusion restricted to trials from 2008–2025. Dual independent screening was applied. Of 47 records identified, 21 studies met the criteria. Across these, the total N was 593 (predominantly male adolescents/young adults; wide range of levels). Results: Prefrontal protocols—most commonly left-dominant dorsolateral prefrontal cortex (DLPFC) (+F3/−F4, ~2 mA, ~20 min)—most consistently improved post-match recovery status/well-being (e.g., fatigue, sleep quality, muscle soreness, stress, mood), and when repeated and/or paired with practice, shortened decision times and promoted more efficient visual search. Effects on classic executive tests were inconsistent, and bilateral anodal DLPFC under fatigue increased risk-tolerant choices. Motor-cortex targeting (C3/C4/Cz) rarely changed rapid force–power performance after a single session—e.g., multiple well-controlled trials found no immediate CMJ gains—but when paired with multi-week training (core/lumbar stability, plyometrics, HIIT, sling), it augmented strength, jump height, sprint/agility, aerobic capacity, and task-relevant EMG. Autonomic markers (exercise HR, early HR recovery) showed time-dependent normalization without specific tDCS effects in single-session, randomized designs. In contrast, a season-long applied program that added prefrontal stimulation to standard recovery reported significantly reduced creatine kinase. Across studies, protocols and masking were athlete-friendly and rigorous (~2 mA for ~20 min; robust sham/blinding), with only mild, transient sensations reported and no serious adverse events. Conclusions: In soccer players, tDCS shows a qualified pattern of benefits that follows a specificity model: prefrontal stimulation can support post-match recovery status/well-being and decision efficiency, while M1-centered stimulation is most effective when coupled with structured training to bias neuromuscular adaptation. Effects are generally modest and heterogeneous; practitioners should treat tDCS as an adjunct, not a stand-alone enhancer, and align montage × task × timing while monitoring individual responses. Full article
(This article belongs to the Section Clinical Rehabilitation)
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Article
Chronotype and Social Jetlag: Impacts on Nutritional Status and Dietary Intake of University Students
by Lyandra Deluchi Loch, Gabriela Iber Correa, Isabela Fernandes Araújo, Amanda Portugal, Gabriela Datsch Bennemann, Caryna Eurich Mazur, Guilherme Welter Wendt, Lirane Elize Defante Ferreto, Carolina Panis, Camila Elizandra Rossi, Kérley Braga Pereira Bento Casaril, Gisele Arruda, Léia Carolina Lucio, Cleide Viviane Buzanello, Geraldo Emílio Vicentini, Claudiceia Risso Pascotto, Aedra Carla Bufalo Kawassaki, Ana Paula Vieira, Dalila Moter Benvegnú, Franciele Ani Caovilla Follador and Mariana Abe Vicente Cavagnariadd Show full author list remove Hide full author list
Obesities 2026, 6(1), 3; https://doi.org/10.3390/obesities6010003 - 9 Jan 2026
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Abstract
The circadian cycle regulates metabolism in response to external stimuli, such as light exposure, sleep schedules, and eating patterns. However, misalignment between internal biological rhythms and social demands can compromise food choices, potentially leading to overweight and obesity. This research aimed to assess [...] Read more.
The circadian cycle regulates metabolism in response to external stimuli, such as light exposure, sleep schedules, and eating patterns. However, misalignment between internal biological rhythms and social demands can compromise food choices, potentially leading to overweight and obesity. This research aimed to assess how a person’s chronotype links to social jet lag (SJL), which in turn would relate to their nutritional status and food consumption patterns as a university student. 617 students from a State University located in the State of Paraná, Brazil, completed a cross-sectional research study that collected sociodemographic information/anthropometrics by means of an online survey. It included self-reported height/weight data and dietary habits. The Munich Chronotype Questionnaire (MCTQ) was utilized to determine each participant’s chronotype classification and SJL calculation. Researchers found that nearly half of the students (49.3%) displayed an Intermediate Chronotype, which is associated with a diet that contained elements of the “Mixed” Diet, meaning there are equal portions of healthy food (Fresh Fruits, Beans, etc.) and unhealthy foods (Sweetened Beverages). The multivariate logistic regression analyses identified age as a significant predictor of obesity risk (OR: 1.15, p < 0.001), while dietary habits such as fruit consumption played a protective role. Additionally, having a breakfast protected them from being classified as obese compared to those who did not eat breakfast (OR = 0.59). Contrary to expectations, late-night supper was not a statistically significant predictor in the adjusted model. Predictors of an Intermediate chronotype included being male and eating morning snacks regularly. The results of this study suggest that students with an intermediate chronotype will predictably have skewed eating patterns, such as skipping breakfast and eating late—both of which affect obesity risks. Nutritional strategies for university students should focus on promoting circadian regularity and optimizing meal timing. Full article
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