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Search Results (164)

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Keywords = skin of colour

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13 pages, 788 KiB  
Article
Advancing Kiwifruit Maturity Assessment: A Comparative Study of Non-Destructive Spectral Techniques and Predictive Models
by Michela Palumbo, Bernardo Pace, Antonia Corvino, Francesco Serio, Federico Carotenuto, Alice Cavaliere, Andrea Genangeli, Maria Cefola and Beniamino Gioli
Foods 2025, 14(15), 2581; https://doi.org/10.3390/foods14152581 - 23 Jul 2025
Viewed by 246
Abstract
Gold kiwifruits from two different farms, harvested at different times, were analysed using both non-destructive and destructive methods. A computer vision system (CVS) and a portable spectroradiometer were used to perform non-destructive measurements of firmness, titratable acidity, pH, soluble solids content, dry matter, [...] Read more.
Gold kiwifruits from two different farms, harvested at different times, were analysed using both non-destructive and destructive methods. A computer vision system (CVS) and a portable spectroradiometer were used to perform non-destructive measurements of firmness, titratable acidity, pH, soluble solids content, dry matter, and soluble sugars (glucose and fructose), with the goal of building predictive models for the maturity index. Hyperspectral data from the visible–near-infrared (VIS–NIR) and short-wave infrared (SWIR) ranges, collected via the spectroradiometer, along with colour features extracted by the CVS, were used as predictors. Three different regression methods—Partial Least Squares (PLS), Support Vector Regression (SVR), and Gaussian process regression (GPR)—were tested to assess their predictive accuracy. The results revealed a significant increase in sugar content across the different harvesting times in the season. Regardless of the regression method used, the CVS was not able to distinguish among the different harvests, since no significant skin colour changes were measured. Instead, hyperspectral measurements from the near-infrared (NIR) region and the initial part of the SWIR region proved useful in predicting soluble solids content, glucose, and fructose. The models built using these spectral regions achieved R2 average values between 0.55 and 0.60. Among the different regression models, the GPR-based model showed the best performance in predicting kiwifruit soluble solids content, glucose, and fructose. In conclusion, for the first time, the effectiveness of a fully portable spectroradiometer measuring surface reflectance until the full SWIR range for the rapid, contactless, and non-destructive estimation of the maturity index of kiwifruits was reported. The versatility of the portable spectroradiometer may allow for field applications that accurately identify the most suitable moment to carry out the harvesting. Full article
(This article belongs to the Section Food Quality and Safety)
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5 pages, 781 KiB  
Clinicopathological Challenge
When Classic Signs Deceive: A Widespread Papulosquamous Eruption in Skin of Colour
by Ji Fung Yong, Claudine Howard-James, Stephen Crowther, Anne-Marie Tobin and Caitriona Hackett
Dermatopathology 2025, 12(3), 21; https://doi.org/10.3390/dermatopathology12030021 - 21 Jul 2025
Viewed by 242
Abstract
A 29-year-old gentleman of African descent presented to the emergency department with a three month history of a rash affecting the trunk, upper limbs, and thighs. The patient was unsure of any triggers and denied any preceding illness, new medications, illicit drug use, [...] Read more.
A 29-year-old gentleman of African descent presented to the emergency department with a three month history of a rash affecting the trunk, upper limbs, and thighs. The patient was unsure of any triggers and denied any preceding illness, new medications, illicit drug use, or recent vaccinations. On examination, there was a widespread papulosquamous eruption characterised by scaly, hyperpigmented papules and plaques involving the trunk, upper arms, and upper thighs. A definitive diagnosis was established through a diagnostic skin biopsy of a fresh lesion. Full article
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21 pages, 15709 KiB  
Article
Preliminary Quantitative Evaluation of the Optimal Colour System for the Assessment of Peripheral Circulation from Applied Pressure Using Machine Learning
by Masanobu Tsurumoto, Takunori Shimazaki, Jaakko Hyry, Yoshifumi Kawakubo, Takeshi Yokoyama and Daisuke Anzai
Sensors 2025, 25(14), 4441; https://doi.org/10.3390/s25144441 - 16 Jul 2025
Viewed by 325
Abstract
Peripheral circulatory failure refers to a condition in which the blood flow through superficial capillaries is markedly reduced or completely occluded. In clinical practice, nurses strictly adhere to regular repositioning protocols to prevent peripheral circulatory failure, during which the skin condition is evaluated [...] Read more.
Peripheral circulatory failure refers to a condition in which the blood flow through superficial capillaries is markedly reduced or completely occluded. In clinical practice, nurses strictly adhere to regular repositioning protocols to prevent peripheral circulatory failure, during which the skin condition is evaluated visually. In this study, skin colour changes resulting from pressure application were continuously captured using a camera, and supervised machine learning was employed to classify the data into two categories: before and after pressure. The evaluation of practical colour space components revealed that the h component of the JCh colour space demonstrated the highest discriminative performance (Area Under the Curve (AUC) = 0.88), followed by the a* component of the CIELAB colour space (AUC = 0.84) and the H component of the HSV colour space (AUC = 0.83). These findings demonstrate that it is feasible to quantitatively evaluate skin colour changes associated with pressure, suggesting that this approach can serve as a valuable indicator for dimensionality reduction in feature extraction for machine learning and is potentially an effective method for preventing pressure-induced skin injuries. Full article
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19 pages, 9987 KiB  
Article
Dye Plants Used by the Indigenous Peoples of the Amur River Basin on Fish Skin Artefacts
by Elisa Palomino
Heritage 2025, 8(6), 195; https://doi.org/10.3390/heritage8060195 - 29 May 2025
Viewed by 524
Abstract
Research on fish skin artefacts’ dyeing practices among the Nivkh, Nanai, Ulchi, Udegei, Oroch, and Negidal Indigenous Peoples of the Amur River basin remains scarce. These fishing communities traditionally crafted fish skin garments, essential to their subsistence and spiritual life, adorning them with [...] Read more.
Research on fish skin artefacts’ dyeing practices among the Nivkh, Nanai, Ulchi, Udegei, Oroch, and Negidal Indigenous Peoples of the Amur River basin remains scarce. These fishing communities traditionally crafted fish skin garments, essential to their subsistence and spiritual life, adorning them with protective motifs. While artistic and cultural aspects of these belongings have been explored, their dyeing techniques remain understudied. This multidisciplinary research examines natural colourants in fish skin artefacts from international museum collections, using historical textual research, ethnographic records, Native Traditional Knowledge, and previous dye analysis by museum conservators. Findings reveal a restricted but meaningful palette of red, blue, yellow, and black colourants, sourced from plants, minerals, and organic materials. Early dyers extracted blue from indigotin-rich plants such as Polygonum tinctorium, or from Commelina communis petals. Red hues were obtained from Carthamus tinctorius petals, introduced through Silk Route trade networks, or from minerals like red ochre. Black was derived from carbon black, while riverine minerals were ground with dry fish roe diluted with water to create additional colour variations. This study first reviews fish skin use in Amur River Indigenous cultures, explores nineteenth-century dyeing materials and techniques, and finally considers broader implications for Indigenous material heritage. Full article
(This article belongs to the Special Issue Dyes in History and Archaeology 43)
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31 pages, 11568 KiB  
Review
The Chemistry of Behind the UV-Curable Nail Polishes
by Inese Mieriņa, Zane Grigale-Sorocina and Ingmars Birks
Polymers 2025, 17(9), 1166; https://doi.org/10.3390/polym17091166 - 25 Apr 2025
Viewed by 1550
Abstract
As far as history tells, people have set efforts both to improve the conditions and to change the visual outfit of the skin, nails, and hair. The first information on nail cosmetics is found in ancient China and Egypt, where various nature-derived compositions [...] Read more.
As far as history tells, people have set efforts both to improve the conditions and to change the visual outfit of the skin, nails, and hair. The first information on nail cosmetics is found in ancient China and Egypt, where various nature-derived compositions were used for changing the colour of the nails. Nowadays more mechanically and chemically durable systems for nail polishes are elaborated. This review focuses on the latest achievements in the field of UV-curable nail polishes. Herein, the polymerization mechanisms of various systems (acrylates, as well as epoxides and thiols) occurring in nail polishes are described. Besides plausible side reactions of the polymerization process are characterized. Thus, the main drawbacks for forming a uniform, perfect layer are illuminated. For effective curing, the choice of photoinitiators may be crucial; thus, various types of photoinitiators as well as their main advantages and disadvantages are characterized. Ensuring effective adhesion between the substrate (human nail) and the polymer film is one of the challenges for the nail polish industry—thus the plausible interactions between the adhesion promoters and the keratin are described. Regarding the film-forming agents, a comprehensive overview of the composition of the traditional UV-curing nail polishes is provided, but the main emphasis is devoted to alternative, nature-derived film-forming agents that could introduce renewable resources into nail cosmetics. Additionally, this review gives short insight into the latest innovations in UV-curing nail cosmetics, like (1) nail polishes with improved pealability, (2) covalently polymer-bonded dyes and photoinitiators, thus reducing the release of the low-molecular compounds or their degradation products, and (3) UV-curing nail polishes as delivery systems for nail treatment medicine. Full article
(This article belongs to the Section Polymer Membranes and Films)
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29 pages, 5223 KiB  
Article
Advancements in Remote Photoplethysmography
by Linas Saikevičius, Vidas Raudonis, Agnė Kozlovskaja-Gumbrienė and Gintarė Šakalytė
Electronics 2025, 14(5), 1015; https://doi.org/10.3390/electronics14051015 - 3 Mar 2025
Viewed by 2610
Abstract
Advancements in camera technology over the past two decades have made image-based monitoring increasingly accessible for healthcare applications. Imaging photoplethysmography (iPPG) and remote photoplethysmography (rPPG) are non-invasive methods for measuring vital signs, such as heart rate, respiratory rate, oxygen saturation, and blood pressure, [...] Read more.
Advancements in camera technology over the past two decades have made image-based monitoring increasingly accessible for healthcare applications. Imaging photoplethysmography (iPPG) and remote photoplethysmography (rPPG) are non-invasive methods for measuring vital signs, such as heart rate, respiratory rate, oxygen saturation, and blood pressure, without physical contact. rPPG utilizes basic cameras to detect physiological changes, while rPPG enables remote monitoring by capturing subtle skin colour variations linked to blood flow. Various rPPG techniques, including colour-based, motion-based, multispectral, and depth-based approaches, enhance accuracy and resilience. These technologies are beneficial not only for healthcare but also for fitness tracking, stress management, and security systems, offering a promising future for contactless physiological monitoring. In this article, there is an overview of these methods and their uniqueness for use in remote photoplethysmography. Full article
(This article belongs to the Special Issue Modern Computer Vision and Image Analysis)
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10 pages, 1313 KiB  
Communication
Outcrossing Levels and Fruit Quality in Single-Cultivar Blocks of a Multi-Cultivar Lychee (Litchi chinensis Sonn.) Orchard
by Stephen J. Trueman and Joel Nichols
Horticulturae 2025, 11(3), 244; https://doi.org/10.3390/horticulturae11030244 - 25 Feb 2025
Viewed by 612
Abstract
Intraspecific diversity is often introduced in orchards to promote cross-pollination, which is essential for self-incompatible crops and beneficial for many self-compatible crops. In lychee, orchards are often planted with multiple cultivars to increase the availability of male flowers, enhancing pollen transfer to female [...] Read more.
Intraspecific diversity is often introduced in orchards to promote cross-pollination, which is essential for self-incompatible crops and beneficial for many self-compatible crops. In lychee, orchards are often planted with multiple cultivars to increase the availability of male flowers, enhancing pollen transfer to female flowers. Typically, this diversity is arranged in single-cultivar blocks, requiring pollinators to transport cross-pollen across rows to reach trees in the middle of each block. We aimed to determine the levels of outcrossing at the edge and in the middle of blocks of Fay Zee Siu, Kaimana, Kwai Mai Pink, Sah Keng, Souey Tung and Wai Chee in a multi-cultivar lychee orchard. We also aimed to determine whether outcrossed fruit have different mass, skin colour and flavour attributes from selfed fruit. All cultivars produced a mixture of outcrossed and selfed fruit. Fay Zee Siu and Kaimana fruit were predominantly outcrossed, Kwai Mai Pink produced slightly more selfed than outcrossed fruit, and Souey Tung displayed high selfing. Outcrossing levels did not differ significantly between the edge and middle rows of these four cultivars. In contrast, Sah Keng and Wai Chee produced more outcrossed fruit in their edge row but more selfed fruit in their middle row. These two cultivars were at the orchard periphery, with another cultivar planted on only one side. Pollinators transported cross-pollen 56–60 m into the middle of blocks when different cultivars were planted on both sides, but this distance decreased to 42–56 m into the blocks when another cultivar was planted on only one side. Cross-pollination had few effects on fruit mass or quality, although pollination by Souey Tung sometimes increased fruit mass or Brix. These findings suggest that interplanting different cultivars of lychee can make effective use of its mixed-mating system, providing additional pollen sources in the orchard, supporting fruitlet retention, and sustaining tree productivity, without contributing greatly to quality variation in each cultivar. Full article
(This article belongs to the Special Issue Orchard Management: Strategies for Yield and Quality)
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26 pages, 16791 KiB  
Article
Practical Dyeing and Technical Imaging: Replicating a Colonial Feather Insignia from Mexico
by Renée Riedler, Julia Zeindl, María Olvido Moreno Guzmán, Carlos Barrera Reyes, Martina Griesser and Nikoletta Sárfi
Heritage 2025, 8(3), 85; https://doi.org/10.3390/heritage8030085 - 20 Feb 2025
Viewed by 814
Abstract
A colonial feather insignia from New Spain dating to the late 16th century is one of a group of seven unique feather objects kept in museums in Austria, Germany, and Mexico. The insignia represents a highly skilled example of a featherworking tradition documented [...] Read more.
A colonial feather insignia from New Spain dating to the late 16th century is one of a group of seven unique feather objects kept in museums in Austria, Germany, and Mexico. The insignia represents a highly skilled example of a featherworking tradition documented in historical sources such as the Florentine Codex. In order to make a replica for the National Museum of Anthropology in Mexico City (MNA), an interdisciplinary team carried out technical and material studies before preparing the necessary raw material. At the centre of this work are bird feathers dyed with organic dye and naturally coloured feathers that cover most of the insignia’s surface. By working with historical documents, artisans, reference collections of bird skin, and the application of multiband imaging (MBI) and fibre optic reflectance spectroscopy (FORS), it was possible to identify both the bird species and the organic dye used or naturally presented in the feathers. Dyeing experiments to colour-match the different shades of red were conducted by applying traditional recipes and materials. The true value of this research is not necessarily in the finished product or outcome but in the journey itself—specifically in the methods developed and the practical experience gained along the way. Full article
(This article belongs to the Special Issue Dyes in History and Archaeology 42)
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14 pages, 1803 KiB  
Article
Discovery of Potential Candidate Genes for Coat Colour in Wuzhishan Pigs by Integrating SNPs and mRNA Expression Analysis
by Qiao Xu, Yabiao Luo, Zhe Chao, Jibin Zhang, Xiaolei Liu, Danqin Tu, Qin Guo, Ruiping Sun, Feng Wang and Meiying Fang
Animals 2024, 14(23), 3493; https://doi.org/10.3390/ani14233493 - 3 Dec 2024
Cited by 2 | Viewed by 957
Abstract
Despite identifying genes regulating the coat colour in Western pig breeds, the genetic basis of the coat colour in Chinese indigenous pigs is still not understood due to the diversity of indigenous breeds and their genetic differences from exotic pigs. In this study, [...] Read more.
Despite identifying genes regulating the coat colour in Western pig breeds, the genetic basis of the coat colour in Chinese indigenous pigs is still not understood due to the diversity of indigenous breeds and their genetic differences from exotic pigs. In this study, 215 Wuzhishan pigs with three coat colour patterns (white, black, and black-back/white-belly) were used to conduct a genome-wide association analysis. We found that genes responsible for the coat colour in the Wuzhishan breed are located on chromosome 8. Ninety-seven genome-wide significant SNPs are related to the animal’s coat colour. Using a haplotype-sharing analysis, we narrowed the potential candidate region to a 10.1 Mb interval encompassing only one gene, RAPGEF2, which participates in the regulation of melanogenesis. Two additional candidate genes, PDGFRA and KIT, are located within 1 Mb of the genome-wide significant SNPs. Gene ontology analysis and literature mining suggest that these candidate genes are associated with the animal’s coat colour. mRNA expression results revealed that RAPGEF2 and PDGFRA had significantly higher expressions in black pigs than in white pigs and higher expressions in black skin than in white skin from the same black-back/white-belly pigs. These results suggest that RAPGEF2 and PDGFRA are potential candidate genes regulating the coat colour in Wuzhishan pigs. Interestingly, mutations of KIT (a gene duplication and a G to A substitution at the splicing site in intron 17) were detected in white Wuzhishan pigs but not in black-back/white-belly or black pigs, suggesting a close genetic relationship between white Wuzhishan pigs and Western white pig breeds. In summary, these results indicate that the expression of RAPGEF2 and PDGFRA may cause the coat colour variation by influencing the deposition of melanin, while the mutation of KIT causes the white coat colour. Our results may provide a theoretical basis for the breeding of white coat colour Wuzhishan pigs, and shed light on the complex genetic background of coat colour variations in indigenous Chinese pig breeds. Full article
(This article belongs to the Section Animal Genetics and Genomics)
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19 pages, 7207 KiB  
Article
Bioactive Silk Revolution: Harnessing Curcuminoid Dye and Chitosan for Superior Antimicrobial Defence and UV Shielding
by Khai Ly Do, Taswar Ahsan, Abdul Wahab, Muhammad Tayyab, Xinqi Yin, Nengjie Pan, Tao Huang, Asim Mushtaq and Miao Su
Pharmaceutics 2024, 16(12), 1510; https://doi.org/10.3390/pharmaceutics16121510 - 24 Nov 2024
Cited by 3 | Viewed by 1409
Abstract
Background/Objectives: The use of natural colourants is gaining attention due to their biocompatibility and functional benefits. This study introduces a different approach using turmeric (Curcuma longa L.) dye extract combined with chitosan to significantly enhance the antibacterial and UV-shielding properties of silk. [...] Read more.
Background/Objectives: The use of natural colourants is gaining attention due to their biocompatibility and functional benefits. This study introduces a different approach using turmeric (Curcuma longa L.) dye extract combined with chitosan to significantly enhance the antibacterial and UV-shielding properties of silk. Methods: The turmeric dye’s chemical composition was analyzed using liquid chromatography mass spectrometry (LC-MS), UV–visible spectroscopy, and Fourier-transform infrared spectroscopy (FTIR). The dyed silk’s colourfastness was tested through rubbing, washing, and light exposure. Results: The chitosan-mordanted silk showed strong antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), as well as antifungal activity against Aspergillus niger (A. niger). It also demonstrated a high ultraviolet protection factor (UPF). For comparison, alum-mordant was used, and chitosan proved more effective. Beyond its use as a dye, turmeric is renowned for its medicinal properties. Its antioxidant, anticancer, and anti-inflammatory properties have been extensively researched, which are primarily linked to its curcuminoid compounds. Turmeric is used in traditional medication to treat digestive issues, arthritis, and skin diseases. Conclusions: This work underscores the innovative use of plant-based dye extracts and natural mordants like chitosan as a sustainable alternative to conventional metallic mordants, paving the way for the evolution of bioactive silk with improved functional properties. Full article
(This article belongs to the Special Issue Bionanomaterials: Fascinating Materials for Biomedical Applications)
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25 pages, 3089 KiB  
Article
A Hybrid Trio-Deep Feature Fusion Model for Improved Skin Cancer Classification: Merging Dermoscopic and DCT Images
by Omneya Attallah
Technologies 2024, 12(10), 190; https://doi.org/10.3390/technologies12100190 - 3 Oct 2024
Cited by 5 | Viewed by 3277
Abstract
The precise and prompt identification of skin cancer is essential for efficient treatment. Variations in colour within skin lesions are critical signs of malignancy; however, discrepancies in imaging conditions may inhibit the efficacy of deep learning models. Numerous previous investigations have neglected this [...] Read more.
The precise and prompt identification of skin cancer is essential for efficient treatment. Variations in colour within skin lesions are critical signs of malignancy; however, discrepancies in imaging conditions may inhibit the efficacy of deep learning models. Numerous previous investigations have neglected this problem, frequently depending on deep features from a singular layer of an individual deep learning model. This study presents a new hybrid deep learning model that integrates discrete cosine transform (DCT) with multi-convolutional neural network (CNN) structures to improve the classification of skin cancer. Initially, DCT is applied to dermoscopic images to enhance and correct colour distortions in these images. After that, several CNNs are trained separately with the dermoscopic images and the DCT images. Next, deep features are obtained from two deep layers of each CNN. The proposed hybrid model consists of triple deep feature fusion. The initial phase involves employing the discrete wavelet transform (DWT) to merge multidimensional attributes obtained from the first layer of each CNN, which lowers their dimension and provides time–frequency representation. In addition, for each CNN, the deep features of the second deep layer are concatenated. Afterward, in the subsequent deep feature fusion stage, for each CNN, the merged first-layer features are combined with the second-layer features to create an effective feature vector. Finally, in the third deep feature fusion stage, these bi-layer features of the various CNNs are integrated. Through the process of training multiple CNNs on both the original dermoscopic photos and the DCT-enhanced images, retrieving attributes from two separate layers, and incorporating attributes from the multiple CNNs, a comprehensive representation of attributes is generated. Experimental results showed 96.40% accuracy after trio-deep feature fusion. This shows that merging DCT-enhanced images and dermoscopic photos can improve diagnostic accuracy. The hybrid trio-deep feature fusion model outperforms individual CNN models and most recent studies, thus proving its superiority. Full article
(This article belongs to the Special Issue Medical Imaging & Image Processing III)
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20 pages, 4537 KiB  
Article
Efficacy Evaluation of Chlorine Dioxide and Hypochlorous Acid as Sanitisers on Quality and Shelf Life of Atlantic Salmon (Salmo salar) Fillets
by Wing H. Chung, Md Reaz Chaklader and Janet Howieson
Foods 2024, 13(19), 3156; https://doi.org/10.3390/foods13193156 - 3 Oct 2024
Cited by 1 | Viewed by 1716
Abstract
Microbial contamination during seafood processing can often lead to a reduction in shelf life and the possibility of food-borne illnesses. Sanitisation with chlorine-based products during seafood processing is therefore sometimes undertaken. This study compared the effects of two sanitisers, chlorine dioxide (ClO2 [...] Read more.
Microbial contamination during seafood processing can often lead to a reduction in shelf life and the possibility of food-borne illnesses. Sanitisation with chlorine-based products during seafood processing is therefore sometimes undertaken. This study compared the effects of two sanitisers, chlorine dioxide (ClO2) and hypochlorous acid (HOCl) at their suggested concentration (5 ppm and 10 ppm; 50 ppm and 100 ppm respectively), on physical, chemical, and microbial qualities of Atlantic salmon (Salmo salar) fillets throughout 7 days of simulated retail display refrigeration. Parameters used for assessment included quality index (QI), drip loss, colour, texture, histology, total volatile base nitrogen (TVB-N), lipid oxidation (malonaldehyde, MDA), pH, and total viable count changes. Results indicated that whilst drip loss increased over the storage time, day 4 and 7 drip loss in both sanitisers decreased significantly compared with the control. There was a linear relationship (R > 0.70) between QI and storage time in all treatments, particularly in regard to skin brightness, flesh odour, and gaping parameters, but treatment differences were not present. Texture parameters including gumminess, chewiness, and hardness increased over time in the control whilst both sanitiser treatments seemed to provide protective effects against texture hardening during storage. The observed softening effects from the sanitiser treatments were aligned with microstructural and cytological changes in the histology results, as evidenced by a reduced fibre–fibre adhesion, myodigeneration, and an increase in interfibrillar space over storage time. Colour, especially chroma (C*), was shown to decrease over time in control, whereas insignificant protective effects were observed in both sanitiser treatments at day 7. Irrespective of treatment and storage time, MDA levels exceeded the acceptable limit on all days, whilst TVB-N levels were below the critical limit. Although pH was influenced by treatment and storage time, the pH was within the normal range. Microbiological results showed that with sanitiser addition, TVC was below the permissible level (106 CFU/g) until day 4 but ClO2 ice (5 ppm), ClO2 (10 ppm), and HOCl (100 ppm) treated fillets all exceeded the limit on day 7. The mixed results on the effect of sanitiser addition on fillet quality and shelf life suggested that further investigation on pathogen reduction, sanitiser introductory method, as well as testing the same treatments in low-fat fish models would be recommended. Full article
(This article belongs to the Section Food Packaging and Preservation)
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15 pages, 350 KiB  
Article
Constitutional Factors and Irradiation as Risk Factors for Thymoma: A European Case–Control Study
by Linda Kaerlev, Mikael Eriksson, Pascal Guénel, Franco Merletti, Maria Morales-Suárez-Varela, Wolfgang Ahrens, Karl-Heinz Jöckel, Agustin Llopis-Gonzalez, Gun Wingren and Lorenzo Simonato
Int. J. Environ. Res. Public Health 2024, 21(9), 1241; https://doi.org/10.3390/ijerph21091241 - 20 Sep 2024
Viewed by 1403
Abstract
Little is known about the aetiology of thymoma. This study aims to identify medical risk factors for thymoma as a systematic approach to new hypotheses on the aetiology of this disease. A European multi-centre case–control study was conducted from 1995 to 1997, including [...] Read more.
Little is known about the aetiology of thymoma. This study aims to identify medical risk factors for thymoma as a systematic approach to new hypotheses on the aetiology of this disease. A European multi-centre case–control study was conducted from 1995 to 1997, including incident cases aged 35–69 years with thymoma. Altogether, we accepted 85 cases and 3350 controls, of which we interviewed 77 cases and 2071 population controls about constitutional factors, medical examinations, and former diseases. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated. Medical examinations with X-ray or radiotherapy performed >20 times at least one year before the thymoma diagnosis indicated a possible risk factor for thymoma (OR 1.58, 95% CI 0.93–2.69). Having the first radiotherapy treatment at least one year before the thymoma diagnosis yielded an OR for thymoma of 2.39; 95% CI (0.96–5.99), and if it was at least five years before, the OR for thymoma was 2.81; 95% CI (1.03–7.72). Having a red/auburn hair colour was associated with thymoma, (OR 3.6, 95% CI 1.4–9.5) whereas having pigmented skin was slightly associated with thymoma (OR 1.8, 95% CI 0.8–3.8). Over twenty instances of X-ray examinations or radiotherapy were identified as potential risk factors for thymoma, along with certain constitutional factors. The observed correlations between benign tumours and thymoma could stem from an inherent predisposition to tumour development or result from detection bias. Given that this is the initial analytical study examining medical risk factors for thymoma, all of the results should be approached with caution, acknowledging the possibility that some findings might be incidental. Full article
17 pages, 1917 KiB  
Article
Cookies Fortified with Polyphenols Extracts: Impact on Phenolic Content, Antioxidant Activity, Inhibition of α-Amylase and α-Glucosidase Enzyme, Colour and Sensory Attractiveness
by Daria Pędziwiatr, Marina Cano Lamadrid and Aneta Wojdyło
Antioxidants 2024, 13(9), 1108; https://doi.org/10.3390/antiox13091108 - 13 Sep 2024
Cited by 3 | Viewed by 2085
Abstract
The goal of the research was to determine the impact of fortification with polyphenolic compounds on (i) sensory attractiveness (global satisfaction, appearance, colour, odour, flavour, sweetness, bitterness), (ii) content of polyphenols and colour (L*, a*, b*) after the baking process and (iii) their [...] Read more.
The goal of the research was to determine the impact of fortification with polyphenolic compounds on (i) sensory attractiveness (global satisfaction, appearance, colour, odour, flavour, sweetness, bitterness), (ii) content of polyphenols and colour (L*, a*, b*) after the baking process and (iii) their bioactive potential (antioxidants activity and inhibiting of α-amylase and α-glucosidase enzyme). Fortification was made with extracts of polyphenolic compounds of selected plant raw materials rich in polyphenols from quince (fruits), tilia (flowers), pomegranate (skin), passion fruit (endocarp), sour cherries (leaves), haskap and chokeberry (berries), silver skin (coffee beans), rosehip (seeds). Depending on the nature of the polyphenol extract, flavan-3-ols (monomeric and polymeric), phenolic acid, flavonols and anthocyanins were identified in the product in amounts ranging from 53.7 to 212.6 mg/100 g DM. Cookies’ colour (L*, a*, b*) depended on the type of polyphenol extract used for fortification. Cookies with haskap, chokeberry and sour cherry presented the highest antioxidant potential. Cookies with chokeberry, haskap and rosehip presented high activity in inhibiting α-amylase (65.5, 60.6 and 62.2% of inhibition, respectively), but cookies with haskap, silver skin and quince in inhibiting α-glucosidase activity (23.0, 20.4 and 21.4% of inhibition, respectively). In the sensory evaluation, the most attractive were cookies with rosehip and pomegranate (6.3 and 5.8 score, respectively), but the lowest ratings were given to cookies with passion fruit and silver skin but especially quince cookies, which obtained the lowest desirability (3.7 score). The acceptability of fortified cookies was determined to the least extent by monomeric flavan-3-ols and phenolic acids (in minus in odour/flavour, bitterness, sweetness and global satisfaction), but anthocyanins, polymeric procyanidins and flavonols had the most significant positive impact on consumer acceptance of the assessed features, i.e., global satisfaction, odour/flavour, sweetness and bitterness (positive consumer drivers). Full article
(This article belongs to the Section Natural and Synthetic Antioxidants)
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15 pages, 272 KiB  
Article
Comparative Study of the Healing Process of Disbudding Wounds in Calves Using Bepanthene® or an Antibiotic Spray
by Gabriela Martins and George Stilwell
Animals 2024, 14(17), 2526; https://doi.org/10.3390/ani14172526 - 30 Aug 2024
Viewed by 1369
Abstract
The process of disbudding female calves is a common procedure in many dairy farms, avoiding injuries caused by horns and reducing feed bunk space requirements. The most common method for disbudding calves is by the use of a cautery iron, responsible for destroying [...] Read more.
The process of disbudding female calves is a common procedure in many dairy farms, avoiding injuries caused by horns and reducing feed bunk space requirements. The most common method for disbudding calves is by the use of a cautery iron, responsible for destroying the horn-generating tissue. After the procedure, wounds may be treated with an antibiotic-based spray. Nowadays, antimicrobial resistance is a worldwide concern in both human and veterinary medicine, highlighting the need to invest in the monitoring of antimicrobial use and in the development of alternative treatments in favour of One Health. The goal of this study is to promote a reduction in the use of antibiotics in farm animals by investigating an alternative treatment for disbudding wounds. Bepanthene® (dexpanthenol, a derivative of pantothenic acid, a component of the B vitamin complex) is a plausible option, since it is widely used in human medicine for the treatment of skin irritations and burns. The comparison of the healing process of disbudding wounds treated with Bepanthene® or a chlortetracycline-based spray was achieved through the presentation of a randomly-ordered sequence of images of the lesions to a panel of convenience-selected and blinded-to-treatment evaluators, composed of seven veterinarian practitioners, five veterinary medicine students, and five human medical field nurses. In order to classify the lesions, the panel applied an adapted format of a validated healing scale (Bates–Jensen Wound Assessment Tool), incorporating seven parameters of evaluation, culminating in the values used for statistical analyses. In the practitioners’ evaluation, a statistically significant effect for the factors of time and treatment in favour of Bepanthene® was found for the parameters “Edges”, “Necrotic Tissue Type”, and “Skin Colour Surrounding Wound”, indicating that Bepanthene® is superior to the spray when considering these parameters of healing. The assessment by the veterinary students showed a significant effect for the factors of time and treatment for the parameters “Necrotic Tissue Type”, in favour of the Bepanthene®, and “Granulation Tissue”, in favour of the antibiotic spray, demonstrating no clear benefit for either treatment. Lastly, the evaluation performed by nurses showed a significant effect for the factors of time and treatment, in favour of the Bepanthene®, for the parameters “Necrotic Tissue Type” and “Skin Colour Surrounding Wound”, leading to the conclusion that Bepanthene® is associated with better and faster healing when compared to the spray. Overall, these findings lead us to suggest that Bepanthene® presents a better healing index compared to a chlortetracycline-based spray, allowing it to be safely used as a substitute to an antimicrobial agent. Full article
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