Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (263)

Search Parameters:
Keywords = sight loss

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
23 pages, 11430 KB  
Article
Symmetry-Aware Gradient Coordination for Physics-Guided Non-Line-of-Sight Imaging
by Yijun Ling, Wenjin Zhao, Mengjia Zhao and Jie Yang
Symmetry 2026, 18(5), 711; https://doi.org/10.3390/sym18050711 - 23 Apr 2026
Viewed by 72
Abstract
Physics-guided computational imaging typically aggregates data fidelity, geometric reconstruction, and sensor consistency into a single scalar loss. In low signal-to-noise ratio (low-SNR) non-line-of-sight imaging, this centralized approach creates asymmetric gradient conflicts where the dominant constraints suppress physically meaningful updates. We propose treating multi-constraint [...] Read more.
Physics-guided computational imaging typically aggregates data fidelity, geometric reconstruction, and sensor consistency into a single scalar loss. In low signal-to-noise ratio (low-SNR) non-line-of-sight imaging, this centralized approach creates asymmetric gradient conflicts where the dominant constraints suppress physically meaningful updates. We propose treating multi-constraint training as a gradient coordination problem rather than scalar balancing. Our framework coordinates heterogeneous objectives through branch-wise gradient routing: soft conflict projection (PCGrad), hard physical constraint enforcement (PhysGuard), learnable sensor calibration, and a staged training protocol that decouples representation learning from nuisance parameter estimation. On held-out test scenes, the fully staged model improved the peak signal-to-noise ratio (PSNR) from 19.09 dB to 20.49 dB and the structural similarity index (SSIM) from 0.67 to 0.71 over the baseline, with consistent gains across the 48, 28, and 25 dB SNR levels. Qualitative evaluation on seven real-world scenes indicates sharper structure recovery and fewer artifacts. In this NLOS setting, gradient-level coordination is more reliable than scalar aggregation under heterogeneous constraints. Full article
(This article belongs to the Section Computer)
19 pages, 7787 KB  
Article
High-Mountain Carnivore Assemblage and Sustainable Conservation Priorities in the K2 Landscape
by Muhammad Shakil, Zubair Shah, Shoaib Hameed, Ejaz Ur Rehman, Fathul Bari, Sadam Hussain, Tahir Mehmood, Shakeel Ahmad, Tahir Mehmood and Muhammad Ali Nawaz
Sustainability 2026, 18(8), 3888; https://doi.org/10.3390/su18083888 - 14 Apr 2026
Viewed by 530
Abstract
Mammalian carnivores play an important role in maintaining the integrity of an ecosystem; therefore, their conservation as an umbrella species ensures the conservation of other species as well as the entire ecosystem. The northern area of Pakistan has a rich diversity of globally [...] Read more.
Mammalian carnivores play an important role in maintaining the integrity of an ecosystem; therefore, their conservation as an umbrella species ensures the conservation of other species as well as the entire ecosystem. The northern area of Pakistan has a rich diversity of globally and regionally significant carnivore species, many of which are threatened mainly due to conflict with humans. In the current study, we used multiple survey techniques: camera trapping, sign surveys, and questionnaire surveys in the Basha–Braldu Valleys of the Central Karakoram National Park (CKNP) during the period 20 May–31 July 2017. The objectives were to document mammalian carnivore diversity and relative abundance and to assess community perceptions of carnivores and human–carnivore conflicts associated with economic losses from livestock depredation. Camera trapping was only carried out in the Basha valley, where 30 motion-triggered cameras were deployed for two months, maintaining a minimum spatial distance of 1 km between the nearest cameras. Sign surveys were carried out in both valleys by dividing the area into 5 km × 5 km grids. Signs of carnivores were searched in a 50 m radius of the sampling point, and a minimum distance of 100 m was maintained between the two nearest sampling points. The questionnaire survey was conducted in communities residing in both valleys. Overall, 140 randomly selected locals from 23 villages were interviewed about the human–carnivore interaction in the area. The questionnaire covered the respondents’ demographics, carnivore sightings and status, economic loss due to livestock depredation, and local perceptions towards carnivores. The study confirmed the presence of seven carnivore species, including the snow leopard (Panthera uncia), grey wolf (Canis lupus), red fox (Vulpes vulpes), brown bear (Ursus arctos), Himalayan lynx (Lynx lynx), stone marten (Martes foina), and weasel (Mustela altaica). Of the total livestock losses reported, carnivores accounted for 30% (394 animals), while 70% (1347 animals) were attributed to disease, resulting in an overall economic loss of USD 138,778 (USD 991 per household). Livestock depredation varied with season, prey type, location, livestock guarding practices, and predator species. Due to high levels of livestock depredation, local communities perceived the grey wolf as the most dangerous carnivore, with many respondents favoring its reduction or elimination. Our findings indicate that the Basha–Braldu Valleys support a rich diversity of globally important carnivore species; however, human–carnivore conflict driven by livestock depredation remains a major conservation challenge. Effective conflict-mitigation interventions are essential to promote sustainable conservation practices and long-term coexistence within these mountain ecosystems. Further studies are recommended to improve the understanding of carnivore population status, distribution, and dietary ecology. Full article
(This article belongs to the Section Environmental Sustainability and Applications)
Show Figures

Figure 1

10 pages, 1085 KB  
Proceeding Paper
Active Reconfigurable Intelligent Surface (ARIS)-Empowered Satellite Positioning Approach for Indoor Environments
by Yu Zhang, Xin Sun, Tianwei Hou, Anna Li, Sofie Pollin, Yuanwei Liu and Arumugam Nallanathan
Eng. Proc. 2026, 126(1), 45; https://doi.org/10.3390/engproc2026126045 - 7 Apr 2026
Viewed by 199
Abstract
To mitigate the loss of satellite navigation signals in indoor environments, we propose an active reconfigurable intelligent surface (ARIS)-empowered satellite positioning approach. Deployed on building structures, ARIS reflects navigation signals to indoor receivers to bypass obstructions, providing high-precision positioning services to receivers in [...] Read more.
To mitigate the loss of satellite navigation signals in indoor environments, we propose an active reconfigurable intelligent surface (ARIS)-empowered satellite positioning approach. Deployed on building structures, ARIS reflects navigation signals to indoor receivers to bypass obstructions, providing high-precision positioning services to receivers in non-line-of-sight (NLoS) areas. The path between ARIS and the receiver is defined as the extended line-of-sight (ELoS) path, and an improved carrier phase observation equation is derived to accommodate this path. The receiver compensates for its clock bias through network time synchronization, corrects the actual satellite–ARIS–receiver signal path to the satellite–receiver distance through a distance correction algorithm, and determines the position using the least squares (LS) method. Simulation results show that the proposed method provides positioning services with errors not exceeding 4 m in indoor environments, with time synchronization accuracy within an error range of 10 ns. Full article
(This article belongs to the Proceedings of European Navigation Conference 2025)
Show Figures

Figure 1

29 pages, 707 KB  
Article
Symmetrical User Fairness in Asymmetric Indoor Channels: A Max–Min Framework for Joint Discrete RIS Partitioning and Power Allocation in NOMA Systems
by Periyakarupan Gurusamy Sivabalan Velmurugan, Vinoth Babu Kumaravelu, Arthi Murugadass, Agbotiname Lucky Imoize, Samarendra Nath Sur and Francisco R. Castillo Soria
Symmetry 2026, 18(4), 563; https://doi.org/10.3390/sym18040563 - 25 Mar 2026
Viewed by 316
Abstract
Reconfigurable intelligent surface (RIS)-assisted non-orthogonal multiple access (NOMA) has emerged as a promising technique to enhance spectral efficiency and coverage in fifth- and sixth-generation wireless networks. However, asymmetric indoor propagation conditions characterized by heterogeneous line-of-sight (LoS) and non-line-of-sight (NLoS) links often degrade user [...] Read more.
Reconfigurable intelligent surface (RIS)-assisted non-orthogonal multiple access (NOMA) has emerged as a promising technique to enhance spectral efficiency and coverage in fifth- and sixth-generation wireless networks. However, asymmetric indoor propagation conditions characterized by heterogeneous line-of-sight (LoS) and non-line-of-sight (NLoS) links often degrade user fairness. This paper investigates a downlink RIS-assisted NOMA system under the standardized 3GPP indoor office (InH) channel model to address fairness-oriented design under realistic link-budget constraints. We formulate an optimization problem for max–min fairness that jointly considers discrete RIS element partitioning and NOMA power allocation to achieve a symmetrical allocation of quality of service (QoS). To enable efficient computation, the non-convex problem is transformed into an epigraph form and solved using a low-complexity, bisection-based quasi-convex optimization framework combined with enumeration over RIS partitions. Numerical results demonstrate significant fairness gains; for instance, doubling the RIS array size yields a substantial improvement in the ergodic max–min rate, corresponding to approximately a 66% gain at moderate transmit power levels. Furthermore, by accounting for practical impairments such as imperfect successive interference cancellation (iSIC), imperfect channel state information (iCSI), and RIS implementation losses, the results reveal that fairness-optimal operation consistently prioritizes the far user to overcome severe indoor NLoS attenuation. The proposed framework is also compared with alternating optimization (AO)-based RIS-NOMA, conventional RIS beamforming without partition and RIS-assisted orthogonal multiple access (OMA) schemes. Simulation results confirm that the proposed framework achieves low computational complexity, making it suitable for practical indoor wireless environments. Full article
(This article belongs to the Special Issue Wireless Communications and Symmetries)
Show Figures

Figure 1

11 pages, 1845 KB  
Article
Acoustic Source Drone Detection System Using Tetrahedral Microphone Array and Deep Neural Networks
by Marian Traian Ghenescu, Veta Ghenescu and Serban Vasile Carata
Sensors 2026, 26(6), 1778; https://doi.org/10.3390/s26061778 - 11 Mar 2026
Viewed by 956
Abstract
The rapid integration of Unmanned Aerial Vehicles (UAVs) into civilian airspace has introduced complex security challenges, particularly regarding the protection of critical infrastructure and personal privacy. While conventional detection mechanisms such as radar and optical sensors are widely deployed, they are frequently limited [...] Read more.
The rapid integration of Unmanned Aerial Vehicles (UAVs) into civilian airspace has introduced complex security challenges, particularly regarding the protection of critical infrastructure and personal privacy. While conventional detection mechanisms such as radar and optical sensors are widely deployed, they are frequently limited by line-of-sight obstructions and the small radar cross-section of modern commercial drones. Acoustic analysis presents a viable passive alternative; however, accurate three-dimensional localization remains a computationally demanding task, further complicated by the use of directional sensors with non-uniform sensitivity patterns. In this paper, a deep learning framework is proposed to address these ambiguities. The method involves the fusion of raw acoustic data with explicit sensor geometry metadata within a neural network architecture. To enhance localization precision, a composite loss function is introduced, which independently optimizes planar and altitude coordinates while penalizing outlier predictions. Experimental validation was conducted using a custom dataset of real-world drone flights, utilizing a distributed array of directional microphones. The results demonstrate that the proposed system effectively mitigates the spatial irregularities of ad hoc sensor deployment, achieving robust localization performance in complex acoustic environments. Full article
(This article belongs to the Special Issue Sensing and Communication for Unmanned Aerial Vehicles Networks)
Show Figures

Figure 1

22 pages, 13205 KB  
Article
Deep Learning Indoor Positioning for Connected Aircraft Cabins: A ResNet Approach with Real-World Validation
by Paul Schwarzbach, Muhammad Ammad, Michael Schultz and Oliver Michler
Sensors 2026, 26(5), 1569; https://doi.org/10.3390/s26051569 - 2 Mar 2026
Viewed by 399
Abstract
Indoor positioning in aircraft cabins presents fundamental challenges arising from severe multipath propagation, non-line-of-sight conditions, and metallic fuselage geometry that degrade radio-based positioning methods. This study validates a residual neural network (ResNet) based deep learning approach for aircraft cabin localization through real-world measurements [...] Read more.
Indoor positioning in aircraft cabins presents fundamental challenges arising from severe multipath propagation, non-line-of-sight conditions, and metallic fuselage geometry that degrade radio-based positioning methods. This study validates a residual neural network (ResNet) based deep learning approach for aircraft cabin localization through real-world measurements in an A320 cabin mockup. The methodology employs dual-technology ranging measurements from Ultra-Wideband and Bluetooth Low Energy, transforming range observations into spatial likelihood representations processed by a ResNet. Experimental validation encompasses 19 distributed measurement positions, evaluated against three baseline methods: iterative least squares, robust least squares with Huber loss, and Bayesian grid filtering. ResNet achieved an overall median positioning error of 0.177 m, achieving lower positioning errors than all three baseline methods. Results confirm that likelihood-based neural network positioning is viable for operational aircraft cabin deployment while identifying performance dependencies on anchor visibility, measurement height, and propagation conditions. The original data is openly available. Full article
Show Figures

Figure 1

23 pages, 10384 KB  
Article
Monitoring and Analysis of Surface Deformation in Mining Area Based on LuTan-1 and Sentinel-1A Data
by Zisu Cheng, Meinan Zheng, Qingbiao Guo, Yingchun Wang, Jinchao Li and Xiang Zhang
Remote Sens. 2026, 18(5), 713; https://doi.org/10.3390/rs18050713 - 27 Feb 2026
Viewed by 412
Abstract
High-intensity mining activities in coal mining areas have produced large-gradient surface deformation, posing severe challenges to deformation monitoring using Interferometric Synthetic Aperture Radar (InSAR) techniques based on C-band Synthetic Aperture Radar (SAR) data. This study systematically evaluated the applicability of L-band LuTan-1 SAR [...] Read more.
High-intensity mining activities in coal mining areas have produced large-gradient surface deformation, posing severe challenges to deformation monitoring using Interferometric Synthetic Aperture Radar (InSAR) techniques based on C-band Synthetic Aperture Radar (SAR) data. This study systematically evaluated the applicability of L-band LuTan-1 SAR (L-SAR) data versus C-band Sentinel-1A data for monitoring mining-induced surface deformation, using the Guqiao Coal Mine in Huainan as the study area. Based on 10 ascending-track and 13 descending-track L-SAR images and 42 Sentinel-1A images, deformation retrievals were performed using Differential InSAR (DInSAR) and the Small Baseline Subset (SBAS) InSAR approach, respectively, and the results were validated against independent levelling measurements. Results indicate that the mean coherence of descending- and ascending-track L-SAR interferometric pairs are 0.42 and 0.45, respectively, substantially higher than Sentinel-1A’s 0.25. In the DInSAR analysis along profile A–A′, the maximum line-of-sight (LOS) displacement obtained from descending- and ascending-track L-SAR are −0.40 m and −0.43 m, respectively, compared with −0.25 m from Sentinel-1A. In the SBAS-InSAR time-series analysis, descending- and ascending-track L-SAR yield 209,418 and 228,388 coherent points, respectively, clearly revealing the temporal evolution of surface deformation; their maximum LOS deformation rates are approximately −1.54 m·yr−1 and −2.0 m·yr−1, respectively. By contrast, Sentinel-1A selects only 81,669 coherent points, with severe loss of coherence in the subsidence center and a maximum LOS deformation rate of about −0.48 m·yr−1. Accuracy validation shows that the Root Mean Square Error (RMSE) of vertical displacements obtained from DInSAR monitoring results based on descending and ascending L-SAR data is 16.1 mm, satisfying the requirement of centimeter-level accuracy for mining area surface subsidence monitoring. The study demonstrates the pronounced advantages of L-SAR for monitoring large-gradient, nonlinear deformation in mining environments. L-band data outperform C-band Sentinel-1A across coherence preservation, deformation sensitivity, and monitoring accuracy, providing a scientific basis for the broader application of domestic L-band SAR satellites in disaster risk assessment and long-term time-series monitoring of mining-induced subsidence. Full article
(This article belongs to the Special Issue Advances in Surface Deformation Monitoring Using SAR Interferometry)
Show Figures

Figure 1

16 pages, 4339 KB  
Article
Reinforcement Learning Technique for Self-Healing FBG Sensor Systems in Optical Wireless Communication Networks
by Rénauld A. Dellimore, Jyun-Wei Li, Hung-Wei Huang, Amare Mulatie Dehnaw, Cheng-Kai Yao, Pei-Chung Liu and Peng-Chun Peng
Appl. Sci. 2026, 16(2), 1012; https://doi.org/10.3390/app16021012 - 19 Jan 2026
Cited by 1 | Viewed by 665
Abstract
This paper proposes a large-scale, self-healing multipoint fiber Bragg grating (FBG) sensor network that employs reinforcement learning (RL) techniques to enhance the resilience and efficiency of optical wireless communication networks. The system features a mesh-structured, self-healing ring-mesh architecture employing 2 × 2 optical [...] Read more.
This paper proposes a large-scale, self-healing multipoint fiber Bragg grating (FBG) sensor network that employs reinforcement learning (RL) techniques to enhance the resilience and efficiency of optical wireless communication networks. The system features a mesh-structured, self-healing ring-mesh architecture employing 2 × 2 optical switches, enabling robust multipoint sensing and fault tolerance in the event of one or more link failures. To further extend network coverage and support distributed deployment scenarios, free-space optical (FSO) links are integrated as wireless optical backhaul between central offices and remote monitoring sites, including structural health, renewable energy, and transportation systems. These FSO links offer high-speed, line-of-sight connections that complement physical fiber infrastructure, particularly in locations where cable deployment is impractical. Additionally, RL-based artificial intelligence (AI) techniques are employed to enable intelligent path selection, optimize routing, and enhance network reliability. Experimental results confirm that the RL-based approach effectively identifies optimal sensing paths among multiple routing options, both wired and wireless, resulting in reduced energy consumption, extended sensor network lifespan, and improved transmission delay. The proposed hybrid FSO–fiber self-healing sensor system demonstrates high survivability, scalability, and low routing path loss, making it a strong candidate for future services and mission-critical applications. Full article
(This article belongs to the Section Electrical, Electronics and Communications Engineering)
Show Figures

Figure 1

23 pages, 5201 KB  
Article
HiFiRadio: High-Fidelity Radio Map Reconstruction for 3D Real-World Scenes
by Ke Liao, Mengyu Ma, Luo Chen, Yifan Zhang and Ning Jing
Technologies 2026, 14(1), 58; https://doi.org/10.3390/technologies14010058 - 12 Jan 2026
Viewed by 639
Abstract
The reconstruction of high-fidelity radio maps is pivotal for wireless network planning but remains challenging due to the tension between physical accuracy and computational efficiency. We propose HiFiRadio, a novel framework that achieves a breakthrough in this balance by integrating centimeter-resolution 3D environmental [...] Read more.
The reconstruction of high-fidelity radio maps is pivotal for wireless network planning but remains challenging due to the tension between physical accuracy and computational efficiency. We propose HiFiRadio, a novel framework that achieves a breakthrough in this balance by integrating centimeter-resolution 3D environmental meshes with semantic-aware propagation modeling. At its core, HiFiRadio introduces a semantic-enhanced 3D indexing structure that efficiently manages complex terrain data, enabling real-time classification of signal paths into line-of-sight, non-line-of-sight, and vegetation-obstructed categories. This classification directly guides a hybrid propagation model, which dynamically applies dedicated loss calculations for buildings and foliage, grounded in physical principles. Extensive experiments demonstrate that HiFiRadio attains an accuracy comparable to commercial ray-tracing tools while being orders of magnitude faster. It also significantly outperforms existing learning-based baselines in both accuracy and scalability, a claim further validated by field measurements. By making high-fidelity, real-time radio map reconstruction practical for large-scale scenes, HiFiRadio establishes a new state of the art with immediate applications in network planning, UAV pathing, and dynamic spectrum access. Full article
(This article belongs to the Topic Challenges and Future Trends of Wireless Networks)
Show Figures

Figure 1

18 pages, 3518 KB  
Article
A Scalable Solution for Node Mobility Problems in NDN-Based Massive LEO Constellations
by Miguel Rodríguez Pérez, Sergio Herrería Alonso, José Carlos López Ardao and Andrés Suárez González
Sensors 2026, 26(1), 309; https://doi.org/10.3390/s26010309 - 3 Jan 2026
Viewed by 698
Abstract
In recent years, there has been increasing investment in the deployment of massive commercial Low Earth Orbit (LEO) constellations to provide global Internet connectivity. These constellations, now equipped with inter-satellite links, can serve as low-latency Internet backbones, requiring LEO satellites to act not [...] Read more.
In recent years, there has been increasing investment in the deployment of massive commercial Low Earth Orbit (LEO) constellations to provide global Internet connectivity. These constellations, now equipped with inter-satellite links, can serve as low-latency Internet backbones, requiring LEO satellites to act not only as access nodes for ground stations, but also as in-orbit core routers. Due to their high velocity and the resulting frequent handovers of ground gateways, LEO networks highly stress mobility procedures at both the sender and receiver endpoints. On the other hand, a growing trend in networking is the use of technologies based on the Information Centric Networking (ICN) paradigm for servicing IoT networks and sensor networks in general, as its addressing, storage, and security mechanisms are usually a good match for IoT needs. Furthermore, ICN networks possess additional characteristics that are beneficial for the massive LEO scenario. For instance, the mobility of the receiver is helped by the inherent data-forwarding procedures in their architectures. However, the mobility of the senders remains an open problem. This paper proposes a comprehensive solution to the mobility problem for massive LEO constellations using the Named-Data Networking (NDN) architecture, as it is probably the most mature ICN proposal. Our solution includes a scalable method to relate content to ground gateways and a way to address traffic to the gateway that does not require cooperation from the network routing algorithm. Moreover, our solution works without requiring modifications to the actual NDN protocol itself, so it is easy to test and deploy. Our results indicate that, for long enough handover lengths, traffic losses are negligible even for ground stations with just one satellite in sight. Full article
(This article belongs to the Special Issue Future Wireless Communication Networks: 3rd Edition)
Show Figures

Figure 1

21 pages, 8478 KB  
Article
ClearSight-RS: A YOLOv5-Based Network with Dynamic Enhancement for Remote Sensing Small Target Detection
by Jie Yuan, Shuyi Feng and Hao Han
Sensors 2026, 26(1), 117; https://doi.org/10.3390/s26010117 - 24 Dec 2025
Cited by 2 | Viewed by 666
Abstract
Small target detection in remote sensing images faces challenges due to complex backgrounds, weak features, and large scale differences. This paper proposes an improved YOLOv5-based network, termed ClearSight-RS, with the full name “Clear and Accurate Small-target Insight for Remote Sensing”. As the name [...] Read more.
Small target detection in remote sensing images faces challenges due to complex backgrounds, weak features, and large scale differences. This paper proposes an improved YOLOv5-based network, termed ClearSight-RS, with the full name “Clear and Accurate Small-target Insight for Remote Sensing”. As the name implies, the network is dedicated to achieving clear feature perception and accurate target localization for small targets in remote sensing images. The improvements focus on three aspects: integrating an improved Dynamic Snake Convolution (DSConv) module into the backbone network to strengthen the extraction of small target boundaries and geometric features, as well as the expression of weak textures; embedding a Bi-Level Routing Attention (BRA) module in the Neck part to enhance target focusing and suppress background interference; and optimizing the detection head by retaining only shallow high-resolution feature layers for prediction, reducing feature loss and redundant computations. Experimental results show that, based on the VEDAI dataset, ClearSight-RS achieves the highest mAP for all 8 vehicle categories; based on the NWPU VHR-10 dataset, its overall mAP reaches 93.8%, significantly outperforming algorithms such as Faster RCNN and YOLOv5l; based on the DOTA dataset, the capability of the proposed BRA module in suppressing background interference and capturing small target features is demonstrated. The network balances accuracy and efficiency, performing prominently in detecting vehicles and multi-category small targets in complex backgrounds, verifying its effectiveness. Full article
(This article belongs to the Special Issue Advanced Pattern Recognition: Intelligent Sensing and Imaging)
Show Figures

Figure 1

21 pages, 835 KB  
Review
Emerging Ocular Pathogen Resistance and Clinically Used Solutions: A Problem That Is More than Meets the Eye
by Marusha Ather and Christopher D. Conrady
Pharmaceuticals 2026, 19(1), 31; https://doi.org/10.3390/ph19010031 - 23 Dec 2025
Cited by 2 | Viewed by 1123
Abstract
Background/Objectives: Antimicrobial resistance (AMR) in ocular infections has become a serious concern with major implications for vision preservation. Bacterial AMR contributed to 4.71 million deaths worldwide in 2021, and ophthalmology mirrors these trends with multidrug resistance rates as high as 66% documented in [...] Read more.
Background/Objectives: Antimicrobial resistance (AMR) in ocular infections has become a serious concern with major implications for vision preservation. Bacterial AMR contributed to 4.71 million deaths worldwide in 2021, and ophthalmology mirrors these trends with multidrug resistance rates as high as 66% documented in some regions and persistently high methicillin resistance among common ocular pathogens. Across regions and care settings, traditional empiric therapies are losing effectiveness against an expanding range of pathogens, resulting in slower recovery, more complications, and, in many cases, permanent vision loss. This review aims to synthesize recent clinical, microbiologic, and pharmacologic evidence on ocular AMR, focusing on recent studies to capture current resistance patterns, therapeutic challenges, and evolving management strategies. Methods: Most included papers were published between 2020 and 2025, with additional foundational studies referenced where appropriate. Reports and systematic reviews addressing bacterial, viral, fungal, and parasitic ocular pathogens were evaluated to characterize current resistance mechanisms and management strategies across ocular pathogens. Results: The eye’s anatomic and physiologic barriers limit drug penetration, often promoting resistance and reducing therapeutic efficacy. Resistance mechanisms vary by pathogens; Pseudomonas keratitis is driven mainly by efflux pumps and biofilm formation, while CMV retinitis’ mutations in UL97 and UL54 are linked with clinical failure, and in MRSA associated Staphylococcus keratitis, the presence of mecA necessitates vancomycin-based therapy across bacterial, viral, fungal, and parasitic infections, with mechanisms such as β-lactamase production, efflux pump overexpression, target-site mutation, and biofilm formation contributing to poor response to standard therapy. MDR Pseudomonas keratitis remains the leading cause of rapidly progressive corneal infection with high risk of perforation and vision loss, while resistant CMV retinitis continues to threaten sight in immunocompromised patients despite antiviral advances. MDR organisms are recalcitrant to treatment and may lead to longer treatment courses and potentially worse outcomes and are discussed in detail within the manuscript. Conclusions: Ocular AMR represents an urgent and expanding clinical challenge. This review centers on the two most encountered multidrug-resistant organisms and their corresponding ocular sites, Pseudomonas aeruginosa (anterior segment) and CMV (posterior segment), while contextualizing them within the broader spectrum of resistant bacterial, viral, fungal, and parasitic pathogens. Despite growing awareness of AMR in ophthalmology, comprehensive surveillance data and longitudinal epidemiologic studies remain limited, making it difficult to track evolving resistance trends or guide region-specific therapy. Preserving vision in the AMR era will require faster diagnostics, improved ocular drug-delivery systems, and pathogen-specific therapies. Full article
(This article belongs to the Section Medicinal Chemistry)
Show Figures

Figure 1

25 pages, 981 KB  
Review
GIS-Enabled Truck–Drone Hybrid Systems for Agricultural Last-Mile Delivery: A Multidisciplinary Review with Insights from a Rural Region
by Imran Badshah, Raj Bridgelall and Emmanuel Anu Thompson
Drones 2025, 9(12), 868; https://doi.org/10.3390/drones9120868 - 16 Dec 2025
Cited by 2 | Viewed by 1416
Abstract
Efficient last-mile delivery remains a critical challenge for rural agricultural logistics, globally, particularly in cold-climate regions with dispersed agricultural operations. Truck–drone hybrids can reduce delivery times but face payload limits, cold-weather battery loss, and beyond-visual-line-of-sight regulations. This review evaluates the potential of GIS-enabled [...] Read more.
Efficient last-mile delivery remains a critical challenge for rural agricultural logistics, globally, particularly in cold-climate regions with dispersed agricultural operations. Truck–drone hybrids can reduce delivery times but face payload limits, cold-weather battery loss, and beyond-visual-line-of-sight regulations. This review evaluates the potential of GIS-enabled truck–drone hybrid systems to overcome infrastructural, environmental, and operational barriers in such settings. This study uses the state of North Dakota (USA) as a representative case because of its cold climate, low density, and weak connectivity. These conditions require different routing and system assumptions than typical regions. The study conducts a systematic review of 81 high-quality publications. It identifies seven interconnected research domains: GIS analytics, truck–drone coordination, smart agriculture integration, rural implementation, sustainability assessment, strategic design, and data security. The findings stipulate that GIS enhances hybrid logistics through route optimization, launch site planning, and real-time monitoring. Additionally, this study emphasizes the rural, low-density context and identifies specific gaps related to cold-weather performance, restrictions to line-of-sight operations, and economic feasibility in ultra-low-density delivery networks. The study concludes with a roadmap for research and policy development to enable practical deployment in cold-climate agricultural regions. Full article
Show Figures

Figure 1

21 pages, 1667 KB  
Article
Advanced Retinal Lesion Segmentation via U-Net with Hybrid Focal–Dice Loss and Automated Ground Truth Generation
by Ahmad Sami Al-Shamayleh, Mohammad Qatawneh and Hany A. Elsalamony
Algorithms 2025, 18(12), 790; https://doi.org/10.3390/a18120790 - 14 Dec 2025
Cited by 2 | Viewed by 1063
Abstract
An early and accurate detection of retinal lesions is imperative to intercept the course of sight-threatening ailments, such as Diabetic Retinopathy (DR) or Age-related Macular Degeneration (AMD). Manual expert annotation of all such lesions would take a long time and would be subject [...] Read more.
An early and accurate detection of retinal lesions is imperative to intercept the course of sight-threatening ailments, such as Diabetic Retinopathy (DR) or Age-related Macular Degeneration (AMD). Manual expert annotation of all such lesions would take a long time and would be subject to interobserver tendencies, especially in large screening projects. This work introduces an end-to-end deep learning pipeline for automated retinal lesion segmentation, tailored to datasets without available expert pixel-level reference annotations. The approach is specifically designed for our needs. A novel multi-stage automated ground truth mask generation method, based on colour space analysis, entropy filtering and morphological operations, and creating reliable pseudo-labels from raw retinal images. These pseudo-labels then serve as the training input for a U-Net architecture, a convolutional encoder–decoder architecture for biomedical image segmentation. To address the inherent class imbalance often encountered in medical imaging, we employ and thoroughly evaluate a novel hybrid loss function combining Focal Loss and Dice Loss. The proposed pipeline was rigorously evaluated on the ‘Eye Image Dataset’ from Kaggle, achieving a state-of-the-art segmentation performance with a Dice Similarity Coefficient of 0.932, Intersection over Union (IoU) of 0.865, Precision of 0.913, and Recall of 0.897. This work demonstrates the feasibility of achieving high-quality retinal lesion segmentation even in resource-constrained environments where extensive expert annotations are unavailable, thus paving the way for more accessible and scalable ophthalmological diagnostic tools. Full article
(This article belongs to the Section Algorithms for Multidisciplinary Applications)
Show Figures

Figure 1

29 pages, 43932 KB  
Article
Study on the Surface Deformation Pattern Induced by Mining in Shallow-Buried Thick Coal Seams of Semi-Desert Aeolian Sand Area Based on SAR Observation Technology
by Tao Tao, Xin Yao, Zhenkai Zhou, Zuoqi Wu and Xuwen Tian
Remote Sens. 2025, 17(21), 3648; https://doi.org/10.3390/rs17213648 - 5 Nov 2025
Viewed by 862
Abstract
In the semi-desert aeolian sand areas of Northern China, surface deformation monitoring with SAR is challenged by loss of coherence due to mobile dunes, seasonal vegetation changes, and large-gradient, nonlinear subsidence from underground mining. This study utilizes PALSAR-2 (L-band, 3 m resolution) and [...] Read more.
In the semi-desert aeolian sand areas of Northern China, surface deformation monitoring with SAR is challenged by loss of coherence due to mobile dunes, seasonal vegetation changes, and large-gradient, nonlinear subsidence from underground mining. This study utilizes PALSAR-2 (L-band, 3 m resolution) and Sentinel-1 (C-band, 30 m resolution) data, applying InSAR and Offset tracking methods combined with differential, Stacking, and SBAS techniques to analyze deformation monitoring effectiveness and propose an efficient dynamic monitoring strategy for the Shendong Coalfield. The main conclusions can be summarized as follows: (1) PALSAR-2 data, which has advantages in wavelength and resolution (L-band, multi-look spatial resolution of 3 m), exhibits better interference effects and deformation details compared to Sentinel-1 data (C-band, multi-look spatial resolution of 30 m). The highly sensitive differential-InSAR (D-InSAR) can promptly detect new deformations, while Stacking-InSAR can accurately delineate the range of rock strata movement. SBAS-InSAR can reflect the dynamic growth process of the deformation range as a whole, and SBAS-Offset is suitable for observing the absolute values and morphology of the surface moving basin. The combined application of Stacking-InSAR and Stacking-Offset methods can accurately acquire the three-dimensional deformation field of mining-induced strata movement. (2) The spatiotemporal process of surface deformation caused by coal mining-induced strata movement revealed by InSAR exhibits good correspondence with both the underground mining progress and the development of ground fissures identified in UAV images. (3) The maximum displacement along the line of sight (LOS) measured in the mining area is approximately 2 to 3 m, which is close to the 2.14 m observed on site and aligns with previous studies. The calculated advance influence angle of the No. 22308 working face in the study area is about 38.3°. The influence angle on the solid coal side is 49°, while that on the goaf side approaches 90°. These findings further deepen the understanding of rock movement and surface displacement parameters in this region. The dynamic monitoring strategy proposed in this study is cost-effective and operational, enhancing the observational effectiveness of InSAR technology for surface deformation due to coal mining in this area, and it enriches the understanding of surface strata movement patterns and parameters in this region. Full article
Show Figures

Figure 1

Back to TopTop