Search Results (54,269)

Urban Water Systems (UWS) are complex infrastructures that interact with energy, food, ecosystems and socio-political systems, and are under growing pressure from climate change and resource depletion. Planning circular interventions in this context requires system-level analysis to avoid fragmented, siloed decisions. This paper develops the Hydrosocial Resource Urban Nexus (HRUN) framework that integrates hydrosocial thinking with the Water–Energy–Food–Ecosystems (WEFE) nexus to guide UWS design. We conduct a structured literature review and analyse different configurations of circular interventions, mapping their synergies and trade-offs across socioeconomic and environmental functions of hydrosocial systems. The framework is operationalised through a typology of circular interventions based on their circularity purpose (water reuse, resource recovery and reuse, or water-cycle restoration) and management scale (from on-site to centralised), while greening degree (from grey to green infrastructure) and digitalisation (integration of sensors and control systems) are treated as transversal strategies that shape their operational profile. Building on this typology, we construct cause–effect matrices for each intervention type, linking recurring operational patterns to hydrosocial functionalities and revealing associated synergies and trade-offs. Overall, the study advances understanding of how circular interventions with different configurations can strengthen or weaken system resilience and sustainability outcomes. The framework provides a basis for integrated planning and for quantitative and participatory tools that can assess trade-offs and governance effects of different circular design choices, thereby supporting the transition to more resilient and just water systems. Full article

Background: Craniocervical pain and temporomandibular disorders (TMDs) are prevalent, interconnected conditions. While Movement Representation Techniques (MRTs) are cognitive interventions targeting central pain mechanisms, their specific efficacy here lacks synthesis. This study systematically analyzes the effectiveness of MRTs, such as motor imagery (MI) and action observation (AO), on pain and function in individuals with craniocervical and orofacial pain. Methods: A systematic review of RCTs (PROSPERO: CRD420251155428) was conducted following PRISMA guidelines. Four databases were searched for studies applying MRTs (MI, AO, laterality discrimination) to adults with craniocervical or orofacial pain. Primary outcomes were pain and functionality. Methodological quality was assessed using the PEDro scale and Cochrane RoB 2 tool. Results: Eight RCTs (n = 362) were included. Methodological quality was high (PEDro scores 8–9). MRTs significantly increased Pressure Pain Threshold (PPT) in the masseter, trapezius, and cervical regions. Functional improvements included enhanced cervical range of motion and sensorimotor control. AO consistently demonstrated superior outcomes. However, results for orofacial variables were derived from asymptomatic subjects. Results for cervical muscle strength were inconsistent. Conclusions: MRTs, especially AO, show potential to reduce pain and improve function in craniocervical disorders. Evidence in symptomatic orofacial pain populations is non-existent. Protocol heterogeneity and limited research groups necessitate further high-quality, multicenter RCTs to establish robust clinical guidelines. Full article

The Erasmus+ YOU4BLUE project represents an interdisciplinary educational initiative aimed at fostering a youth culture of sustainability through hands-on learning, scientific literacy, and critical thinking focused on the marine environment. The project aimed to encourage lasting behavioural change and empower young people to act. It engaged secondary school students aged 14 to 18 on three Mediterranean islands (Sardinia, Crete, and Mallorca) through a blended Place-Based Education (PBE) model that integrates online learning with local, experiential activities. Forty-nine students completed a pre-assessment questionnaire measuring baseline marine ecosystem knowledge, sustainability-related behaviours, and attitudes toward the sea. Following three international exchanges involving the learning activities, roughly the same cohort of students completed post-activity surveys assessing self-perceived knowledge gains and intercultural interaction. Qualitative data from emotional mapping, field observations, and group reflections complemented the quantitative analysis. The results indicate substantial self-perceived increases in students’ understanding of marine ecosystems (+1.0 to +1.7 points on a 5-point scale), enhanced collaboration with international peers, and strengthened environmental awareness. Across all three sites, students applied their learning by co-designing proposals addressing local coastal challenges, demonstrating emerging civic responsibility and the ability to integrate scientific observations into real-world problem solving. These findings suggest that combining place-based education, citizen science, and participatory methods can effectively support the development of sustainability competences among youth in coastal contexts. This study contributes empirical evidence to the growing literature on education for sustainable development and highlights the value of blended, experiential, and intercultural approaches in promoting environmentally responsible behaviour. Full article

Tubular pump systems (TPSs) represent a critical class of large-scale turbomachinery for low-head water transport, where mechanical reliability is often challenged by complex internal flow dynamics. Pressure pulsations in pump systems induce vibrations that adversely affect performance, emphasizing the need for effective control mechanisms to ensure stable operation. In tubular pumps, unsteady pressure pulsations are typically driven by rotor–stator interactions; however, the behavior of these pulsations in the absence of impeller rotation remains poorly understood. In this study, a novel comparative investigation is conducted to elucidate the effect of impeller rotation on pressure pulsations characteristic by examining two scenarios: normal impeller operation at rated speed and a completely stationary (zero-speed) impeller condition. Experiments were performed on a model low-head tubular pump, measuring dynamic pressures at four key locations across a range of flow rates. Time–frequency analysis using the continuous wavelet transform (CWT) and the wavelet coherence transform (WTC) was applied to delineate the unsteady pressure features. The results demonstrate that under normal rotation, pressure pulsations are dominated by pronounced periodic components at the impeller’s rotational frequency and its harmonics, with the strongest fluctuation amplitudes observed near the impeller outlet region. In contrast, with the impeller held stationary, these distinct periodic peaks vanish, replaced by broadband, irregular fluctuations. Crucially, WTC analysis revealed that significant coherence between the two operational states was confined to low frequencies (≈16.7–50 Hz), particularly at the impeller inlet, highlighting the presence of low-frequency dynamics likely associated with system-scale hydraulic compliance or inlet flow non-uniformity, independent of impeller rotation. These findings confirm the pivotal role of impeller rotation in generating periodic pressure pulsations while providing new insight into the underlying unsteady flow mechanisms in tubular pumps. Full article

Access to an unobstructed view of the outside through a window has been shown to play a critical role in supporting occupants’ visual comfort, psychological well-being, and cognitive performance, as it provides environmental connection and reduces stress. The aim of this study was to investigate how window view assessment ratings differ between “view owners” (individuals with long-term experience of the view) and “view observers” (those who view photos of a view). Findings from 12 in-person workshops on window view assessment are presented. The participants were 207 students from six European universities. Each participant presented their window view as “view owner”, while the remining students rated it on the 1–9 Likert scale as “view observers”. The ratings given by the “view owners” (prior to workshops) were significantly higher than those given by the “view observers”, showing the influence of familiarity and long-term experience. The additional contextual information about the interior and narrative descriptions provided orally by the “view owners” had a small positive effect. Night views were rated lower than day views by the “view observers”. The findings highlight the impact of long-term experience on the assessment of the window view and encourage the inclusion of night-view in recommendations. Full article

Background/objective: To evaluate the effectiveness of resin infiltration in managing anterior molar incisor hypomineralization (MIH) defects, focusing on color improvement, lesion size reduction, sensitivity outcomes and patient aesthetic perception. Enamel defects in MIH result from a combination of environmental, systemic, and genetic factors, indicating a multifactorial etiology. These defects, particularly in anterior teeth, pose significant aesthetic and emotional challenges due to their high visibility. This study provides one of the few prospective clinical evaluations of resin infiltration for anterior MIH lesions, assessing not only objective clinical outcomes but also patients’ aesthetic perception. It further introduces a patient-centered approach by comparing aesthetic evaluations made by children and dental professionals over time. Methods: A total of 109 MIH-affected anterior teeth were treated using Icon^® resin infiltration (DMG, Hamburg, Germany) in this registered prospective clinical study (ClinicalTrials.gov: NCT05597956). Participants were classified as children (6–12 years) and adolescents (13–17 years) according to standard pediatric age definitions. Of these, 101 teeth were available for evaluation at the 6-month follow-up due to patient loss to follow-up. The evaluation included photographic follow-up, measurement of lesion size and color, and assessment of sensitivity. During follow-up visits, patients rated the appearance of their lesions using the FDI scale. Results: Before treatment, spectrophotometric analysis showed that lesions exhibited a reddish hue (mean a* = 2.12), were distinctly yellowish (mean b* = 23.20), and clearly differed from surrounding enamel (ΔE = 8.62). The brightness level (L* = 69.81) indicated medium-high luminosity. Lesion size was reduced by an average of 4.5 percentage points. Significant increases in L values and reductions in a* and b* components were observed, with clinically perceptible ΔE changes. Sensitivity improved in 36.6% of patients, who reported a 1–2 point decrease on the SCASS. Moreover, patients’ aesthetic perception significantly improved after Icon^® infiltration resin. Conclusions: Resin infiltration produced noticeable improvements in color, reduced lesion size and sensitivity, and enhanced aesthetic perception, making it a valuable treatment option for managing MIH-affected anterior teeth in children. Full article

Background: Workplace violence (WPV) is a pervasive occupational hazard in healthcare that undermines staff safety and quality of care. In Bulgaria, WPV remains widespread and underreported, despite recent legislative initiatives. This study assessed healthcare professionals’ perceptions of the effectiveness of WPV prevention strategies and examined how prior exposure shapes these perceptions. Methods: A nationwide cross-sectional online survey was conducted in December 2024 with 944 healthcare professionals from multiple sectors. Participants rated the perceived effectiveness of 11 prevention strategies, including environmental/security measures, organizational, and national-level interventions, on a three-point scale. Friedman ANOVA with Kendall’s W assessed overall strategy rankings, while Mann–Whitney U tests with rank-biserial correlations compared specific effectiveness ratings between subgroups defined by WPV exposure (experienced or witnessed vs. not exposed in the previous 12 months). Results: In the previous 12 months, 34.7% of respondents reported direct WPV, and 43.4% had either experienced or witnessed incidents. Friedman ANOVA indicated significant differences in perceived effectiveness across strategies (Kendall’s W = 0.13), with stronger differentiation among violence-exposed respondents (W = 0.37) than among non-exposed respondents (W = 0.09). National-level interventions and security/response measures were consistently ranked the highest. Mann–Whitney tests showed significantly higher endorsement of most strategies among violence-exposed professionals, with large effect sizes for security measures and enforcement of sanctions. Conclusions: Bulgarian healthcare professionals view WPV prevention as requiring a multicomponent approach that integrates robust national policy with organizational and environmental measures. Direct exposure to violence is associated with stronger support for security-focused and national interventions. These findings inform context-specific, evidence-based WPV prevention programs for Bulgarian healthcare facilities. Full article

Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic disorder marked by impaired insulin action, pancreatic β-cell dysfunction, and the involvement of several interconnected mechanisms, including inflammation, oxidative stress, and epigenetic alterations. Despite progress in conventional therapies, achieving durable glycemic control and minimizing complications remain major challenges. This review discusses the emerging role of bioactive phytochemicals—such as curcumin, berberine, resveratrol, flavonoids, and polysaccharides—in modulating essential molecular pathways including AMPK, PI3K/AKT, and cAMP/PKA, which contribute to enhanced insulin sensitivity, glucose regulation, and β-cell protection. These natural compounds also influence gut microbiota modulation and epigenetic mechanisms, offering additional metabolic and anti-inflammatory benefits. This review synthesizes evidence from peer-reviewed studies published between 2000 and 2024, incorporating bibliometric trends showing an increasing research focus on phytochemicals for T2DM management. However, limitations such as low solubility, instability, and poor absorption restrict their clinical application. Advances in nanotechnology-based delivery systems, including nanoparticles, liposomes, and nanoemulsions, have shown potential to overcome these barriers by improving stability, bioavailability, and targeted delivery of phytochemicals. The integration of gut microbiota modulation with nanocarrier-enabled phytochemical therapy supports a precision medicine approach for managing T2DM. Preliminary clinical evidence highlights significant improvements in glycemic control and inflammatory status, yet further large-scale, well-controlled trials are essential to ensure safety, optimize dosages, and standardize combination regimens. Overall, phytochemical therapies, reinforced by nanotechnology and microbiota modulation, present a promising, safe, and holistic strategy for T2DM management. Continued interdisciplinary research and clinical validation are crucial for translating these advances into effective therapeutic applications and reducing the global diabetes burden. Full article

Dairy cow body temperature is a key physiological indicator that reflects metabolic level, immune status, and environmental stress responses, and it has been widely used for early disease recognition. Infrared thermography (IRT), as a non-contact imaging technique capable of remotely acquiring the surface radiation temperature distribution of animals, is regarded as a powerful alternative to traditional temperature measurement methods. Under practical cowshed conditions, IRT images of dairy cows are easily affected by complex background interference and generally suffer from low resolution, poor contrast, indistinct boundaries, weak structural perception, and insufficient texture information, which lead to significant degradation in target detection and temperature extraction performance. To address these issues, a lightweight detection model named YOLOv11n-CGSD is proposed for dairy cow IRT images, aiming to improve the accuracy and robustness of region of interest (ROI) detection and body temperature extraction under complex background conditions. At the architectural level, a C3Ghost lightweight module based on the Ghost concept is first constructed to reduce redundant feature extraction while lowering computational cost and enhancing the network capability for preserving fine-grained features during feature propagation. Subsequently, a space-to-depth convolution module is introduced to perform spatial rearrangement of feature maps and achieve channel compression via non-strided convolution, thereby improving the sensitivity of the model to local temperature variations and structural details. Finally, a dynamic sampling mechanism is embedded in the neck of the network, where the upsampling and scale alignment processes are adaptively driven by feature content, enhancing the model response to boundary temperature changes and weak-texture regions. Experimental results indicate that the YOLOv11n-CGSD model can effectively shift attention from irrelevant background regions to ROI contour boundaries and increase attention coverage within the ROI. Under complex IRT conditions, the model achieves P, R, and mAP50 values of 89.11%, 86.80%, and 91.94%, which represent improvements of 3.11%, 5.14%, and 4.08%, respectively, compared with the baseline model. Using T_max as the temperature extraction parameter, the maximum error (Max. Error) and mean error (MAE. Error) in the lower udder region are reduced by 33.3% and 25.7%, respectively, while in the around the anus region, the Max. Error and MAE. Error are reduced by 87.5% and 95.0%, respectively. These findings demonstrate that, under complex backgrounds and low-quality IRT imaging conditions, the proposed model achieves lightweight and high-performance detection for both lower udder (LU) and around the anus (AA) regions and provides a methodological reference and technical support for non-contact body temperature measurement of dairy cows in practical cowshed production environments. Full article

Background/Objectives: This umbrella review critically evaluates the available evidence on psychobiotics for depressive and anxiety symptoms, emphasizing methodological quality, consistency of findings, and persistent gaps in the literature. Methods: A comprehensive search was conducted across PubMed/MEDLINE, Scopus, Web of Science, SciELO, Cochrane, and EBSCO (May–June 2025) to identify systematic reviews with meta-analyses of randomized controlled trials examining probiotic, prebiotic, and synbiotic interventions in adults with depressive and/or anxiety symptoms or diagnoses. Two reviewers independently screened studies, extracted data, and evaluated methodological quality using AMSTAR-2. Additional bibliometric, conceptual, and psychometric features were mapped, including geographical origin, publication timeline, scale distribution, and citation-based connectivity. Results: Thirty systematic reviews and meta-analyses were included. Methodological quality was predominantly moderate, low, or critically low in 76.6% of reviews. Probiotic interventions demonstrated consistent benefits for MDD (SMD = −0.50 [95% CI: −0.58 to −0.42], p = 0.0001). However, findings for anxiety were markedly inconsistent, despite the modest improvements in specific subgroups (SMD = −0.19 [95% CI: −0.28 to −0.10]; p < 0.01). Prebiotics for MDD interventions showed limited positive results (SMD = −0.25 [95% CI: −0.47 to −0.03]; p = 0.03). For anxiety, the effects are inconclusive (SMD = −0.07 [95% CI: −0.30 to 0.10]; p = 0.18). Evidence for synbiotics was scarce. Citation-mapping revealed a fragmented and unevenly connected evidence base. Conclusions: The current evidence suggests that probiotics may confer beneficial effects on depressive and anxiety symptoms; however, the same cannot be said for prebiotics and synbiotics. Evidence for the efficacy of prebiotics and synbiotics to treat depression and anxiety is still insufficient or heterogeneous. Registration: CRD420251164884. Full article

Recent advances in satellite observations have expanded the use of Sea Surface Temperature (SST) and Sea Surface Height (SSH) data in climate and oceanography, yet their low spatial resolution limits fine-scale analyses. We propose HiT_DS, a modular hierarchical Transformer framework for high-resolution downscaling of SST and SSH fields. To address challenges in multiscale feature representation and physical consistency, HiT_DS integrates three key modules: (1) Enhanced Dual Feature Extraction (E-DFE), which employs depth-wise separable convolutions to improve local feature modeling efficiently; (2) Gradient-Aware Attention (GA), which emphasizes dynamically important high-gradient structures such as oceanic fronts; and (3) Physics-Informed Loss Functions, which promote physical realism and dynamical consistency in the reconstructed fields. Experiments across two dynamically distinct oceanic regions demonstrate that HiT_DS achieves improved reconstruction accuracy and enhanced physical fidelity, with selective module combinations tailored to regional dynamical conditions. This framework provides an effective and extensible approach for oceanographic data downscaling. Full article

When a fire occurs in a tunnel during construction, the smoke cannot be discharged in time and continues to settle near the ground, which threatens the safety of personnel. It is essential to understand smoke layer distribution for safe evacuation. To fill the knowledge gap for the spatio-temporal distribution of the smoke layer, a series of fire experiments are carried out in 1/20 reduced-scale tunnel models. Multiple variables are considered, including longitudinal fire location, heat release rate, aspect ratio of the main tunnel, and the inclined shaft length. Two fire scenarios are defined according to the longitudinal fire location in the main tunnel: near the upstream closed end (scenario 1) and near the downstream closed end (scenario 2). The results show that the structural evolution of the smoke layer inside the main tunnel experiences roughly three stages: single-layer smoke flow stage, transition stage, and two-layer smoke flow stage. In different fire scenarios, the reasonable N value is 10, determined by comparing the smoke layer interface height (h_s) predicted by the N-percentage method with the observed results. Moreover, we find that the FDS simulation method has significant deviation in predicting poor stratification situations. Furthermore, the spatio-temporal distributions of h_s in the main tunnel are predicted based on N = 10. The coupled effects of heat release rate and the longitudinal fire location on the h_s values are analyzed. The t_ar value (time of smoke arrival at the respiratory height) is determined, and its spatial variations are predicted. By comparing the t_ar values at position 2^# (near the inclined shaft) in different fire scenarios, we can provide a reference for the evacuation of personnel. Full article

This study systematically investigates the effects of key process parameters in wire arc additive manufacturing (WAAM) on the surface morphology, geometric dimensions, microstructure, and microhardness of single-bead single-layer deposits fabricated from 2209 duplex stainless steel. Using a controlled variable approach, the influences of wire feed speed, travel speed, oscillation pattern, oscillation frequency, and oscillation amplitude on the deposition quality were examined. Experimental results indicate that wire feed speed and travel speed significantly affect the bead width, height, and fusion zone morphology, with optimal ranges identified as 4.5–6.5 m/min and 5–6 mm/s, respectively. Among the oscillation patterns, sinusoidal and figure-eight trajectories resulted in uniform deposition distribution and a refined microstructure, whereas the circular pattern led to fish-scale surface features and coarse grains. The optimal oscillation frequency and amplitude were determined to be 4 Hz and 4 mm, respectively, under which the deposits exhibited high surface quality, no defects other than the depression in the arc extinction zone, and the microhardness remains stable in the range of 280–290 HV. Comprehensive analysis indicates that investigating the influence of these process parameters on the morphology, microstructure, and hardness of DSS2209 single-bead deposits can effectively enhance the overall performance of WAAM-fabricated 2209 duplex stainless steel components, thereby providing a reliable foundation for subsequent multi-layer and multi-bead deposition. Full article

Resting-state functional connectivity (rsFC) provides insight into the intrinsic organization of brain networks and is increasingly recognized as a sensitive marker of age-related neural changes. Functional near-infrared spectroscopy (fNIRS) offers a portable and cost-effective approach to measuring rsFC, including in naturalistic settings. However, its sensitivity to age-related alterations in network topology remains poorly characterized. Here, we applied graph-based analysis to resting-state fNIRS data from 57 healthy participants, including 26 young adults (YA, 18–30 years) and 31 older adults (OA, 50–77 years). We observed that older adults exhibited a marked attenuation of low-frequency oscillation (LFO) power across all hemoglobin contrasts, corresponding to a 5–6-fold reduction in spectral power. In addition, network analysis revealed altered topological organization under matched sparsity conditions, characterized by reduced degree heterogeneity and increased segregation in older adults, with the strongest differences observed in the default mode (DMN), auditory, and frontoparietal control (FPC) networks. Network visualizations further indicated a shift toward more right-lateralized and posterior hub organization in older adults. Together, the coexistence of reduced oscillatory power and increased connectivity suggests that fNIRS-derived rsFC reflects combined neural and non-neural hemodynamic influences, including increased coherence arising from age-related vascular and systemic physiological processes. Overall, our findings demonstrate that fNIRS is sensitive to age-related changes in large-scale hemodynamic network organization. At the same time, sensitivity to non-neural hemodynamics highlights the need for cautious interpretation, but it may provide complementary, clinically relevant signatures of aging-related changes. Full article

The operation of the superheated steam temperature system significantly impacts the safety and economy of thermal power units. To ensure its stable operation under large-scale variable load conditions, a modified active disturbance rejection control strategy based on parameter adaptation is proposed. Firstly, a typical superheated steam temperature system model is introduced, and the cascade control structure is applied to the model. Then, on this basis, a modified active disturbance rejection control strategy based on parameter adaptation is proposed, and the parameter tuning method of the modified active disturbance rejection control is introduced. Finally, the control performance of the proposed control strategy under a wide range of variable loads is verified through comparative simulations under nominal working conditions and uncertain working conditions. To further illustrate the effectiveness of the proposed strategy, the method is applied to a certain 660 MW unit in the field. After implementing the method, the fluctuation range of superheated steam temperature on the A and B sides decreased to only 34.0% and 53.0% of the original, respectively, and the fluctuation variance on the A and B sides decreased to only 28.5% and 43.3% of the original, respectively. The above field application results fully demonstrate that the control strategy proposed does not merely remain at the theoretical simulation level, but is a key technical means that can be effectively implemented and effectively solve the problem of superheated steam temperature control in thermal power units. Full article