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22 pages, 734 KiB  
Article
Compulsive Buying Behaviors and Dietary Patterns in the Context of the Three-Factor Eating Questionnaire (TFEQ)
by Ewa Jerzyk, Natalia Gluza and Dobrosława Mruk-Tomczak
Sustainability 2025, 17(15), 6903; https://doi.org/10.3390/su17156903 - 29 Jul 2025
Viewed by 227
Abstract
Exploring the interactions between compulsive buying and dietary practices is crucial in terms of understanding these behaviors from a behavioral standpoint. This paper investigates the relationships between compulsive buying (CB) and non-compulsive buying (non-CB), focusing on the influence of dietary habits (TFEQ), body [...] Read more.
Exploring the interactions between compulsive buying and dietary practices is crucial in terms of understanding these behaviors from a behavioral standpoint. This paper investigates the relationships between compulsive buying (CB) and non-compulsive buying (non-CB), focusing on the influence of dietary habits (TFEQ), body mass index (BMI), and emotional valence. The study involved a representative sample of 707 Polish adults and employed tools such as the Compulsive Buying Scale, the Three-Factor Eating Questionnaire (TFEQ), and the Emotional Appetite Questionnaire (EMAQ). The results revealed that compulsive buyers (CBs) had higher levels of cognitive restraint, emotional eating, and uncontrolled eating than non-compulsive buyers (non-CBs). Importantly, emotional valence—which includes both positive and negative emotions—significantly influenced dietary behaviors, illustrating the complex role emotions play in food consumption. Additionally, the results highlighted that the BMI significantly affects these relationships, suggesting different eating patterns across BMI categories. This study underscores the need for targeted interventions focusing on psychological and nutritional aspects to address these interconnected compulsive behaviors. Full article
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19 pages, 2239 KiB  
Article
Winter Thermal Resilience of Lightweight and Ground-Coupled Mediumweight Buildings: An Experimental Study During Heating Outages
by Marta Gortych and Tadeusz Kuczyński
Energies 2025, 18(15), 4022; https://doi.org/10.3390/en18154022 - 29 Jul 2025
Viewed by 188
Abstract
Thermal resilience is critical for building safety in cold climates during heating outages. This study presents full-scale experimental data from two residential buildings in Poland, tested during the winter of 2024–2025 under both typical and extreme outdoor conditions. The buildings—a lightweight timber-frame structure [...] Read more.
Thermal resilience is critical for building safety in cold climates during heating outages. This study presents full-scale experimental data from two residential buildings in Poland, tested during the winter of 2024–2025 under both typical and extreme outdoor conditions. The buildings—a lightweight timber-frame structure and a mediumweight masonry structure with ground coupling—were exposed to multi-day heating blackouts, and their thermal responses were monitored at a high temporal resolution. Several resilience indicators were used, including the resistance time (RT), degree of disruption (DoD), and hours of safety threshold (HST). Additionally, two time-based metrics—the time to threshold (Tx) and temperature at X-hours (T(tx))—were introduced to improve classification in long-duration scenarios. The weighted unmet thermal performance (WUMTP) index was also implemented and validated using experimental data. The results show that thermal mass and ground coupling significantly improved passive resilience, enabling the mediumweight building to maintain temperatures above 15 °C for over 60 h without heating. This study provides new empirical evidence of passive survivability in blackout conditions and supports the development of time-sensitive assessment tools for cold climates. The findings may inform future updates to building codes and retrofit guidelines. Full article
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13 pages, 543 KiB  
Article
Subclinical Hypothyroidism in Moderate-to-Severe Psoriasis: A Cross-Sectional Study of Prevalence and Clinical Implications
by Ricardo Ruiz-Villaverde, Marta Cebolla-Verdugo, Carlos Llamas-Segura, Pedro José Ezomo-Gervilla, Jose Molina-Espinosa and Jose Carlos Ruiz-Carrascosa
Diseases 2025, 13(8), 237; https://doi.org/10.3390/diseases13080237 - 25 Jul 2025
Viewed by 181
Abstract
Background: Psoriasis is a chronic inflammatory skin disease linked to systemic comorbidities, including metabolic, cardiovascular, and autoimmune disorders. Thyroid dysfunction, particularly hypothyroidism, has been observed in patients with moderate-to-severe psoriasis, suggesting possible shared inflammatory pathways. Objectives: This study aims to explore [...] Read more.
Background: Psoriasis is a chronic inflammatory skin disease linked to systemic comorbidities, including metabolic, cardiovascular, and autoimmune disorders. Thyroid dysfunction, particularly hypothyroidism, has been observed in patients with moderate-to-severe psoriasis, suggesting possible shared inflammatory pathways. Objectives: This study aims to explore the relationship between psoriasis and thyroid dysfunction in adults with moderate-to-severe psoriasis undergoing biologic therapy to determine whether psoriasis predisposes individuals to thyroid disorders and to identify demographic or clinical factors influencing this association. Materials and Methods: A cross-sectional study included adult patients with moderate-to-severe psoriasis receiving biologic therapy, recruited from the Psoriasis Unit at the Dermatology Department of Hospital Universitario San Cecilio in Granada, Spain, from 2017 to 2023. Patients with mild psoriasis or those treated with conventional systemic therapies were excluded. The data collected included demographics and clinical characteristics, such as age, sex, BMI (body mass index), and psoriasis severity (psoriasis severity was evaluated using the Psoriasis Area Severity Index (PASI), body surface area (BSA) involvement, Investigator’s Global Assessment (IGA), pruritus severity using the Numerical Rating Scale (NRS), and impact on quality of life through the Dermatology Life Quality Index (DLQI)). Thyroid dysfunction, including hypothyroidism and subclinical hypothyroidism, was assessed based on records from the Endocrinology Department. Results: Thyroid dysfunction was found in 4.2% of patients, all classified as hypothyroidism, primarily subclinical. The affected patients were generally older, with a mean age of 57.4 years. No significant differences in psoriasis severity (PASI, BSA) or treatment response were observed between patients with and without thyroid dysfunction. Conclusion: Our findings suggest hypothyroidism is the main thyroid dysfunction in psoriatic patients, independent of psoriasis severity. The lack of impact on psoriasis severity suggests hypothyroidism may be an independent comorbidity, warranting further research into shared inflammatory mechanisms. Full article
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16 pages, 1817 KiB  
Article
Is Brazilian Jiu-Jitsu a Traumatic Sport? Survey on Italian Athletes’ Rehabilitation and Return to Sport
by Fabio Santacaterina, Christian Tamantini, Giuseppe Camarro, Sandra Miccinilli, Federica Bressi, Loredana Zollo, Silvia Sterzi and Marco Bravi
J. Funct. Morphol. Kinesiol. 2025, 10(3), 286; https://doi.org/10.3390/jfmk10030286 - 25 Jul 2025
Viewed by 307
Abstract
Background: Brazilian Jiu-Jitsu (BJJ) is a physically demanding sport associated with a notable risk of musculoskeletal injuries. Understanding injury patterns, rehabilitation approaches, and psychological readiness to return to sport (RTS) is essential for prevention and management strategies. This study aimed to investigate injury [...] Read more.
Background: Brazilian Jiu-Jitsu (BJJ) is a physically demanding sport associated with a notable risk of musculoskeletal injuries. Understanding injury patterns, rehabilitation approaches, and psychological readiness to return to sport (RTS) is essential for prevention and management strategies. This study aimed to investigate injury characteristics among Italian BJJ athletes, assess their rehabilitation processes and psychological recovery, and identify key risk factors such as belt level, body mass index (BMI), and training load. Methods: A cross-sectional survey was conducted among members of the Italian BJJ community, including amateur and competitive athletes. A total of 360 participants completed a 36-item online questionnaire. Data collected included injury history, rehabilitation strategies, RTS timelines, and responses to the Injury-Psychological Readiness to Return to Sport (I-PRRS) scale. A Random Forest machine learning algorithm was used to identify and rank potential injury risk factors. Results: Of the 360 respondents, 331 (92%) reported at least one injury, predominantly occurring during training sessions. The knee was the most frequently injured joint, and the action “attempting to pass guard” was the most reported mechanism. Most athletes (65%) returned to training within one month. BMI and age emerged as the most significant predictors of injury risk. Psychological readiness scores indicated moderate confidence, with the lowest levels associated with playing without pain. Conclusions: Injuries in BJJ are common, particularly affecting the knee. Psychological readiness, especially confidence in training without pain, plays a critical role in RTS outcomes. Machine learning models may aid in identifying individual risk factors and guiding injury prevention strategies. Full article
(This article belongs to the Special Issue Understanding Sports-Related Health Issues, 2nd Edition)
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30 pages, 5617 KiB  
Article
Scale Considerations and the Quantification of the Degree of Fracturing for Geological Strength Index (GSI) Assessments
by Paul Schlotfeldt, Jose (Joe) Carvalho and Brad Panton
Appl. Sci. 2025, 15(15), 8219; https://doi.org/10.3390/app15158219 - 24 Jul 2025
Viewed by 216
Abstract
This paper provides research that shows that the scale and quantification of the degree of fracturing in a rock mass should and can be considered when estimating geological strength index (GSI) ratings for rock mass strength and deformability estimates. In support of this [...] Read more.
This paper provides research that shows that the scale and quantification of the degree of fracturing in a rock mass should and can be considered when estimating geological strength index (GSI) ratings for rock mass strength and deformability estimates. In support of this notion, a brief review is provided to demonstrate why it is imperative that scale is considered when using GSI in engineering design. The impact of scale and scale effects on the engineering response of a rock mass typically requires a definition of fracture intensity relative to the volume or size of rock mass under consideration and the relative scale of the project being built. In this research three volume scales are considered: the volume of a structural domain, a representative elemental REV, and unit volume. A theoretical framework is established that links these three volume scales together, how they are estimated, and how they relate to parameters used to estimate engineering behaviour. Analysis of data from several examples and case histories for real rock masses is presented that compares and validates the use of a new and innovative but practical method (a sphere of unit volume) to estimate fracture intensity parameters VFC or P30 (fractures/m3) and P32 (fracture area—m2/m3) that is included on the vertical axis of the volumetric V-GSI chart. The research demonstrates that the unit volume approach to calculating VFC and P32 used in the V-GSI system compares well with other methods of estimating these two parameters (e.g., discrete fracture network (DFN) modelling). The research also demonstrates the reliability of the VFC-correlated rating scale included on the vertical axis of the V-GSI chart for use in estimating first-order strength and deformability estimates for rock masses. This quantification does not negate or detract from geological logic implicit in the original graphical GSI chart. Full article
(This article belongs to the Special Issue Rock-Like Material Characterization and Engineering Properties)
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17 pages, 1121 KiB  
Article
Physical Activity and Psychological Symptoms in University Teachers Improved Post-COVID-19 Lockdown, but Sedentary Behavior Persisted
by Laura M. Navarro-Flores, Brajan J. Vivas-Sánchez, Jose María De La Roca-Chiapas, Victor K. Rodrigues Matsudo, Maciste H. Macias and Katya Vargas-Ortiz
Healthcare 2025, 13(15), 1772; https://doi.org/10.3390/healthcare13151772 - 22 Jul 2025
Viewed by 483
Abstract
Background/Objectives: This study aimed to determine whether the movement patterns and mental health of university teachers changed after returning to on-site class activities following the COVID-19 lockdown. Specifically, it compared levels of physical activity (PA), sedentary behavior time (SBT), active breaks (ABs), [...] Read more.
Background/Objectives: This study aimed to determine whether the movement patterns and mental health of university teachers changed after returning to on-site class activities following the COVID-19 lockdown. Specifically, it compared levels of physical activity (PA), sedentary behavior time (SBT), active breaks (ABs), and symptoms of depression, anxiety, and stress among university teachers during online and on-site teaching periods. We also analyzed the association between movement patterns with psychological and anthropometric variables. Methods: University teachers who engaged in online teaching activities because of the COVID-19 restrictions and returned to on-site classes were included. Each teacher wore an accelerometer and answered the Depression Anxiety Stress Scales. The following parameters were assessed: SBT, light (LPA), moderate (MPA), and vigorous (VPA) (min/day); moderate–vigorous PA (MVPA) (min/week); steps/day and ABs/day. Results: Thirty-seven teachers with complete data from both phases were included. Once the on-site teaching activities resumed, LPA (9 min/day), MPA (6 min/day), total PA (20 min/day), MVPA (49 min/week), and steps/day (1100) significantly increased. While SBT showed no changes, ABs/day bouts increased. Depression and stress symptoms improved upon returning to on-site teaching activities. A positive association was identified between SBT and waist circumference (WC). There were negative associations between steps/day and MVPA with body mass index (BMI), steps/day with WC, and LPA with stress symptoms. Conclusions: Upon returning to on-site teaching activities, PA levels, steps/day, and ABs/day bouts all increased, although SBT remained elevated compared with during the lockdown. The teachers’ psychological symptoms improved. PA was associated with better health markers, while SBT was associated with increased WC. Full article
(This article belongs to the Special Issue Health Promotion to Improve Health Outcomes and Health Quality)
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12 pages, 874 KiB  
Article
Open-Label Uncontrolled, Monocentric Study to Evaluate the Efficacy and Safety of the Electromagnetic Field and Negative Pressure in the Treatment of Cellulite
by Antonio Scarano, Antonio Calopresti, Salvatore Marafioti, Gianluca Nicolai and Erda Qorri
Life 2025, 15(7), 1148; https://doi.org/10.3390/life15071148 - 21 Jul 2025
Viewed by 373
Abstract
Cellulite is a widespread aesthetical dermatological condition affecting a significant proportion of postpubertal women, characterized by dimpled skin, primarily on the thighs, buttocks, and hips, which has an important psychological impact. Cellulite, also called lipodystrophy or oedematosclerotic panniculitis, causes an aesthetic change in [...] Read more.
Cellulite is a widespread aesthetical dermatological condition affecting a significant proportion of postpubertal women, characterized by dimpled skin, primarily on the thighs, buttocks, and hips, which has an important psychological impact. Cellulite, also called lipodystrophy or oedematosclerotic panniculitis, causes an aesthetic change in the skin that affects the epidermis, dermis, hypodermis and subcutaneous fat in different ways. The aim of the present prospective study research was to evaluate the efficacy of electromagnetic field and negative pressure in the treatment of cellulite. Methods: A total of 35 women with an average age of 40, ranging from 18 to 50 (mean 32.2 ± 7.48), with a body mass index between 18.5 and 26.9 (mean 22 ± 3.01), were enrolled in this study. The degree of cellulite of the patients was assessed clinically using the Cellulite Severity Scale (CSS) and Nürnberger–Müller classification. All patients received one session per week for a total 12 treatment sessions with Bi-one® LifeTouchTherapy medical device (Expo Italia Srl—Florence—Italy), which generates a combination of vacuum and electromagnetic fields (V-EMF). Total treatment time was approximately 20–30 min per patient. The GAIS score, Cellulite Severity Scale (CSS) and Nürnberger–Müller classification for cellulite was evaluated 1 month after the 12 treatments with LifeTouchTherapy. Results: A statistical difference was recorded in cellulite improvement by visual analog scale (VAS) and global aesthetic improvement scale (GAIS). Conclusions: The results of the present prospective clinical study show the efficacy and safety of Bi-one® LifeTouchTherapy in the treatment of cellulite. Electromagnetic fields combined with negative pressure therapy promote tissue regeneration and reduce fibrosis, which results in visible cosmetic improvements of cellulite. Full article
(This article belongs to the Collection Clinical Trials)
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22 pages, 840 KiB  
Article
Relationship Between Family Support, C-Reactive Protein and Body Mass Index Among Outpatients with Schizophrenia
by Argyro Pachi, Athanasios Tselebis, Evgenia Kavourgia, Nikolaos Soultanis, Dimitrios Kasimis, Christos Sikaras, Spyros Baras and Ioannis Ilias
Healthcare 2025, 13(14), 1754; https://doi.org/10.3390/healthcare13141754 - 20 Jul 2025
Viewed by 391
Abstract
Background/Objectives: Schizophrenia has been associated with increased inflammatory and metabolic disturbances. Perceived family support potentially affects inflammatory and metabolic biomarkers. The aim of this study was to determine the interrelations between family support, C-reactive protein (CRP) and Body Mass Index (BMI) in a [...] Read more.
Background/Objectives: Schizophrenia has been associated with increased inflammatory and metabolic disturbances. Perceived family support potentially affects inflammatory and metabolic biomarkers. The aim of this study was to determine the interrelations between family support, C-reactive protein (CRP) and Body Mass Index (BMI) in a sample of outpatients with schizophrenia. Importantly, this study sought to elucidate the effect of perceived family support on inflammatory processes among patients with schizophrenia. Methods: In this cross-sectional correlation study, 206 outpatients with schizophrenia in clinical remission completed a standardized self-report questionnaire that assessed family support (Family Support Scale—FSS). Sociodemographic, clinical and laboratory data were also recorded. Results: Among the participants, 49.5% had detectable CRP values (≥0.11 mg/dL), whereas 14.6% had positive CRP levels (>0.6 mg/dL). There was a significant difference in CRP levels among the different BMI groups (normal weight/overweight vs. obese). For obese patients, the crude odds ratios (ORs) for detectable and positive CRP values were 1.980 (95% confidence interval (CI) [1.056, 3.713]) and 27.818 (95% CI [6.300, 122.838]), respectively. Significant positive correlations were observed among CRP, BMI and illness duration, while scores on the FSS were negatively associated with these variables. The results of binary logistic regression analysis indicated that both BMI and family support were significant factors in determining the likelihood of having positive CRP levels, with each unit increase in the BMI associated with a 17% (95% CI [0.025, 0.337]) increase in the odds, and with each unit increase in family support leading to an 8.6% (95% CI [0.018, 0.15]) decrease. A moderation analysis revealed that the association between family support and the probability of having positive CRP levels depends on the BMI value, but only for obese patients did the protective effect of family support significantly decrease the magnitude of the risk of having positive CRP (b = −0.1972, SE = 0.053, OR = 0.821, p = 0.000, 95% CI [−0.3010, −0.0934]). Conclusions: The effect of perceived family support on inflammatory responses becomes evident in cases where beyond metabolic complications, inflammatory processes have already been established. Increased perceived family support seems to protect against inflammation and, notably, the association between low perceived family support and increased inflammation is even stronger. Establishing the role of family involvement during the treatment of patients with schizophrenia through inflammatory processes is a novelty of this study, emphasizing the need to incorporate family therapy into psychiatric treatment plans. However, primary interventions are considered necessary for patients with schizophrenia in order to maintain their BMI within normal limits and avoid the subsequent nosological sequelae. Full article
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12 pages, 251 KiB  
Article
Efficacy of Transcranial Direct Current Stimulation in the Treatment of Anorexia Nervosa—Interim Results from an Ongoing, Double-Blind, Randomized, Placebo-Controlled Clinical Trial
by Zuzanna Rząd, Joanna Rog, Natalia Kajka, Maksymilian Seweryn, Jakub Patyk and Hanna Karakuła-Juchnowicz
J. Clin. Med. 2025, 14(14), 5040; https://doi.org/10.3390/jcm14145040 - 16 Jul 2025
Viewed by 290
Abstract
Background/Objectives: Anorexia nervosa (AN) is a severe disorder with limited treatment efficacy. This interim analysis aimed to assess the preliminary efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core AN symptoms, stress, depression, low self-esteem, and BMI in adolescent [...] Read more.
Background/Objectives: Anorexia nervosa (AN) is a severe disorder with limited treatment efficacy. This interim analysis aimed to assess the preliminary efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core AN symptoms, stress, depression, low self-esteem, and BMI in adolescent females, to determine the rationale for continuing the study. Methods: A single-center, randomized, double-blind, placebo-controlled trial included 20 adolescent females with AN assigned to an active tDCS group (n = 10) or a sham group (n = 10). The intervention involved 30 sessions over three weeks, targeting the dorsolateral prefrontal cortex. Outcomes were assessed at baseline, post-treatment, and follow-up using the Eating Attitudes Test (EAT-26) for eating disorder symptoms, the Perceived Stress Scale (PSS-10) for stress, the Beck Depression Inventory (BDI) for depression, the Rosenberg Self-Esteem Scale (SES) for self-esteem, and body mass index (BMI) measurements. Safety and tolerability were assessed using the tDCS Side Effects Questionnaire. Results: Eating disorder symptoms significantly decreased in the active tDCS group at study end (p = 0.003) and follow-up (p = 0.02), while no significant changes were observed in the sham group. Although BMI increased more in the active group (13.78%) than in the sham group (7.31%), this difference was not statistically significant (p = 0.10). Conclusions: Adverse effects were mild and transient, with no serious safety concerns reported. Based on the results of this interim analysis, the study will proceed due to promising efficacy outcomes and good treatment tolerability. Full article
(This article belongs to the Section Mental Health)
10 pages, 248 KiB  
Article
Psychiatric Comorbidities Associated with Food Addiction in Post-Bariatric Patients: Toward Personalized Mental Health Screening and Postoperative Care
by Ligia Florio, Maria Olivia Pozzolo Pedro, Kae Leopoldo, Maria Amalia Accari Pedrosa and João Mauricio Castaldelli-Maia
J. Pers. Med. 2025, 15(7), 313; https://doi.org/10.3390/jpm15070313 - 14 Jul 2025
Viewed by 260
Abstract
Background: Food addiction (FA) is an emerging construct that mirrors the behavioral and neurobiological characteristics of substance use disorders. Despite growing interest, its association with specific psychiatric disorders among bariatric patients remains understudied. Objective: Our aim was to examine the prevalence and strength [...] Read more.
Background: Food addiction (FA) is an emerging construct that mirrors the behavioral and neurobiological characteristics of substance use disorders. Despite growing interest, its association with specific psychiatric disorders among bariatric patients remains understudied. Objective: Our aim was to examine the prevalence and strength of associations between FA and seven major psychiatric disorders in individuals who underwent bariatric surgery. Methods: In a sample of 100 post-bariatric patients referred for psychiatric evaluation, FA was assessed using the modified Yale Food Addiction Scale 2.0 (mYFAS 2.0), and psychiatric disorders were diagnosed using the Mini International Neuropsychiatric Interview (MINI). Logistic regression models were used to estimate adjusted odds ratios (aORs) for the association between FA and each psychiatric disorder, controlling for sex, age, body mass index (BMI), employment status, the number of children, clinical comorbidities, physical activity, family psychiatric history, and region of residence. Results: FA was present in 51% of the sample. Descriptive analyses revealed a significantly higher prevalence of major depressive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder, agoraphobia, obsessive–compulsive disorder, and bulimia nervosa among individuals with FA. Multivariate models showed robust associations between FA and bulimia nervosa (aOR = 19.42, p < 0.05), generalized anxiety disorder (aOR = 2.88, p < 0.05), obsessive–compulsive disorder (aOR = 6.64, p < 0.05), agoraphobia (aOR = 3.14, p < 0.05), social anxiety disorder (aOR = 4.28, p < 0.05) and major depressive disorder (aOR = 2.79, p < 0.05). Conclusions: FA is strongly associated with a range of psychiatric comorbidities in post-bariatric patients, reinforcing the need for comprehensive mental health screening in this population. These findings underscore the potential role of FA as a clinical marker for stratified risk assessment, supporting more personalized approaches to mental health monitoring and intervention following bariatric surgery. Full article
(This article belongs to the Special Issue Recent Advances in Bariatric Surgery)
12 pages, 351 KiB  
Article
Associations Between Sleep, Appetite, and Food Reward over 6 Months in Black Emerging Adults—Findings from the Sleep, Health Outcomes and Body Weight (SHOW) Pilot Study
by Hannah R. Koch, Jesse N. L. Sims, Stephanie Pickett, Graham Finlayson, Laurie Wideman and Jessica McNeil
Nutrients 2025, 17(14), 2305; https://doi.org/10.3390/nu17142305 - 13 Jul 2025
Viewed by 351
Abstract
Background/Objectives: Imposed sleep restriction leads to increased feelings of appetite and hedonic eating behaviors (or food rewards). No study to date has assessed home-based measures of sleep with appetite and food rewards exclusively in Black emerging adults (ages 18–28 years), despite higher [...] Read more.
Background/Objectives: Imposed sleep restriction leads to increased feelings of appetite and hedonic eating behaviors (or food rewards). No study to date has assessed home-based measures of sleep with appetite and food rewards exclusively in Black emerging adults (ages 18–28 years), despite higher risks of short sleep and obesity in this population. We examined associations between 6-month changes in sleep with changes in appetite and food reward in Black emerging adults. Methods: Fifteen Black emerging adults (12 females; age, 21 ± 2.5 years; body mass index, 25.7 ± 4.5 kg/m2; body fat, 25.8 ± 11.9%) completed two identical 7-day measurement bursts at baseline and 6 months. Sleep (duration, efficiency, and architecture) was captured via 7 days of actigraphy and 2 nights of in-home polysomnography. During a laboratory visit, participants completed appetite measures (desire to eat, hunger, fullness, and prospective food consumption) via visual analog scales before and for 3 h following standard breakfast intake. The food reward for the fat and sweet categories of food was measured before lunch with the Leeds Food Preference Questionnaire. Results: Fasting fullness scores decreased from baseline to 6 months (−8.9 mm, p < 0.01) despite increases in body weight (2.6 kg, p < 0.01) and waist circumference (2.4 cm, p = 0.03). Increases in actigraph-measured sleep duration were associated with decreases in fasting desire to eat (r = −0.58, p = 0.04). Increases in actigraph-measured sleep efficiency were also associated with decreases in explicit liking for sweet foods (r = −0.60, p = 0.03). Conclusions: Our findings suggest that improvements in sleep duration and sleep efficiency may lead to decreased feelings of appetite and food reward in Black emerging adults. Full article
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20 pages, 1370 KiB  
Article
Interpretable Machine Learning for Osteopenia Detection: A Proof-of-Concept Study Using Bioelectrical Impedance in Perimenopausal Women
by Dimitrios Balampanos, Christos Kokkotis, Theodoros Stampoulis, Alexandra Avloniti, Dimitrios Pantazis, Maria Protopapa, Nikolaos-Orestis Retzepis, Maria Emmanouilidou, Panagiotis Aggelakis, Nikolaos Zaras, Maria Michalopoulou and Athanasios Chatzinikolaou
J. Funct. Morphol. Kinesiol. 2025, 10(3), 262; https://doi.org/10.3390/jfmk10030262 - 11 Jul 2025
Viewed by 367
Abstract
Objectives: The early detection of low bone mineral density (BMD) is essential for preventing osteoporosis and related complications. While dual-energy X-ray absorptiometry (DXA) remains the gold standard for diagnosis, its cost and limited availability restrict its use in large-scale screening. This study investigated [...] Read more.
Objectives: The early detection of low bone mineral density (BMD) is essential for preventing osteoporosis and related complications. While dual-energy X-ray absorptiometry (DXA) remains the gold standard for diagnosis, its cost and limited availability restrict its use in large-scale screening. This study investigated whether raw bioelectrical impedance analysis (BIA) data combined with explainable machine learning (ML) models could accurately classify osteopenia in women aged 40 to 55. Methods: In a cross-sectional design, 138 women underwent same-day BIA and DXA assessments. Participants were categorized as osteopenic (T-score between −1.0 and −2.5; n = 33) or normal (T-score ≥ −1.0) based on DXA results. Overall, 24.1% of the sample were classified as osteopenic, and 32.85% were postmenopausal. Raw BIA outputs were used as input features, including impedance values, phase angles, and segmental tissue parameters. A sequential forward feature selection (SFFS) algorithm was employed to optimize input dimensionality. Four ML classifiers were trained using stratified five-fold cross-validation, and SHapley Additive exPlanations (SHAP) were applied to interpret feature contributions. Results: The neural network (NN) model achieved the highest classification accuracy (92.12%) using 34 selected features, including raw impedance measurements, derived body composition indices such as regional lean mass estimates and the edema index, as well as a limited number of categorical variables, including self-reported physical activity status. SHAP analysis identified muscle mass indices and fluid distribution metrics, features previously associated with bone health, as the most influential predictors in the current model. Other classifiers performed comparably but with lower precision or interpretability. Conclusions: ML models based on raw BIA data can classify osteopenia with high accuracy and clinical transparency. This approach provides a cost-effective and interpretable alternative for the early identification of individuals at risk for low BMD in resource-limited or primary care settings. Full article
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17 pages, 626 KiB  
Article
Does Vitamin D Supplementation Slow Brain Volume Loss in Multiple Sclerosis? A 4-Year Observational Study
by Weronika Galus, Mateusz Winder, Aleksander J. Owczarek, Anna Walawska-Hrycek, Michalina Rzepka, Aleksandra Kaczmarczyk, Joanna Siuda and Ewa Krzystanek
Nutrients 2025, 17(14), 2271; https://doi.org/10.3390/nu17142271 - 9 Jul 2025
Viewed by 580
Abstract
Background and Aims: Vitamin D is currently well regarded for its pleiotropic effects on the immune system, stimulating an anti-inflammatory response and enhancing immune tolerance. Vitamin D deficiency is an established risk factor for multiple sclerosis (MS). Additionally, lower vitamin D serum levels [...] Read more.
Background and Aims: Vitamin D is currently well regarded for its pleiotropic effects on the immune system, stimulating an anti-inflammatory response and enhancing immune tolerance. Vitamin D deficiency is an established risk factor for multiple sclerosis (MS). Additionally, lower vitamin D serum levels are associated with worse disease outcomes. However, current randomized clinical trials provide conflicting evidence about the beneficial role of vitamin D on disease progression. Most studies have evaluated the effect of vitamin D supplementation on clinical and radiological activity, yet very few have examined the impact on brain atrophy. Methods: A 4-year observational, non-interventional study design was applied to evaluate the association between vitamin D supplementation and disease progression. Altogether, 132 relapsing–remitting multiple sclerosis patients were enrolled in the study (97 subjects in the group with vitamin D supplementation and 35 subjects in the group without supplementation). The analyzed groups were similar in terms of age, body mass index, sun exposure, comorbidities, nicotinism, duration of the disease, and current treatment. The number of relapses, Expanded Disability Status Scale assessments, and the number of new/enlarged T2-weighted lesions and gadolinium-enhancing lesions in magnetic resonance imagining analyses, as well as 25-hydroxyvitamin D serum levels, were assessed every 12 months of a 4-year follow-up, whereas brain atrophy was assessed at the baseline and after 36 months using two-dimensional measurements. Results: After 36 months, a significant increase in atrophy was observed in both groups; however, patients without vitamin D supplementation had a significantly higher increase in intercaudate distance, third ventricle width, and bicaudate ratio after 36 months of observation (p < 0.05). Vitamin D supplementation among the studied group did not affect other disease activity outcomes. Conclusions: Our study revealed an observed association between vitamin D supplementation and reduced brain atrophy in patients with MS. Randomized controlled trials are required to establish the impact of vitamin D supplementation on brain atrophy progression. Full article
(This article belongs to the Section Clinical Nutrition)
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9 pages, 914 KiB  
Article
Three-Dimensional Model Improves Body Image Perception After Bariatric Surgery
by Cyril Gauthier, Matthieu Poussier, Célia Lloret-Linares, Marc Danan and Anamaria Nedelcu
J. Clin. Med. 2025, 14(13), 4787; https://doi.org/10.3390/jcm14134787 - 7 Jul 2025
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Abstract
Background: Despite losing weight, the majority of subjects retained an obese view of themselves. The aim of the study was to evaluate the usefulness of a 3D modeling tool in improving the body image of patients who have undergone bariatric surgery. Methods [...] Read more.
Background: Despite losing weight, the majority of subjects retained an obese view of themselves. The aim of the study was to evaluate the usefulness of a 3D modeling tool in improving the body image of patients who have undergone bariatric surgery. Methods: Morbidly obese subjects involved in a medico-surgical obesity management program and having undergone a Roux en Y Gastric Bypass (RYGB) or a sleeve gastrectomy (SG) were prospectively included during their usual postoperative medical follow-up. The figure rating scale (FRS), body image questionnaire, and Hospital Anxiety Depression Scale test were performed. The FRS was assessed before and after visualizing their body image using a 3D modeling tool. Distributions between the groups for gender (female vs. male) and type of surgery (gastric bypass vs. sleeve gastrectomy) were tested with a Pearson’s chi2 independence test. The significance threshold was p < 0.05. Results: We included 140 adults with sleeve gastrectomy (72.9%; n = 102) or gastric bypass (27.1%; n = 38). The mean time from surgery was 308.3 ± 111.4 days (63–511). Participants were mostly female (77.9%; n = 109). Nearly half of the subjects who had undergone bariatric surgery almost one year before modified their body perception after visualizing their avatar thanks to a 3D modeling tool. One third reduced their FRS score (“perceived body”) after visualizing their avatar. FRS score and body mass index (BMI) following surgery (“real body”) were significantly correlated before and after visualizing the 3D avatar, with a stronger correlation after visualizing the 3D avatar. Conclusions: A 3D modeling tool may improve body perception after weight loss in subjects with bariatric surgery. Being simple, non-invasive, not expansive, and easy to use during a consultation and to understand for the patient, a regular use of this tool may be largely implemented in clinical practice. Its usefulness in improving body image, mood disorders, and eating disorders and the further success of the surgery should be further evaluated. Full article
(This article belongs to the Special Issue New Approaches in Bariatric Surgery)
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16 pages, 570 KiB  
Article
Comparison of Guided Exercise and Self-Paced Exercise After Lumbar Spine Surgery: A Randomized Controlled Trial
by Seong Son, Han Byeol Park, Kyeong Sik Kong, Byung Rhae Yoo, Woo Kyung Kim and Jae Ang Sim
Life 2025, 15(7), 1070; https://doi.org/10.3390/life15071070 - 4 Jul 2025
Viewed by 482
Abstract
Background: The efficacy of postoperative exercise rehabilitation after spine surgery is controversial, and a protocol for exercise treatment and detailed outcomes based on functional activity have not yet been established. This study aimed to determine the efficacy of exercise rehabilitation after lumbar spine [...] Read more.
Background: The efficacy of postoperative exercise rehabilitation after spine surgery is controversial, and a protocol for exercise treatment and detailed outcomes based on functional activity have not yet been established. This study aimed to determine the efficacy of exercise rehabilitation after lumbar spine surgery. Methods: A prospective, randomized controlled trial was conducted in 40 patients who underwent lumbar spine surgery (20 patients each in the exercise and control groups) for 12 weeks. Clinical outcomes were assessed using the visual analog scale (VAS) for pain and EuroQol-5 Dimensions 5-Level version (EQ-5D-5L). Body proportions, including body mass index, total muscle mass, and body fat percentage were analyzed. Functional activity was evaluated based on the range of motion of the lumbar spine, strength and endurance of lumbar flexion/extension, flexibility, 6 min walking test, single-leg stance, coordination, and gait pattern analysis. Results: The exercise group showed significantly greater improvement in VAS for pain (66.67% versus 20.00%, p < 0.001) and EQ-5D-5L (45.56% versus 20.00, p = 0.039) compared to the control group. Serial assessment revealed significant improvement in strength of lumbar flexion/extension, 6 min walking test, single-leg stance, coordination, and gait patterns in the exercise group compared to the control group. In particular, the single-leg stance time for the affected leg improved more markedly in the exercise group (280.9% versus 48.7%, p < 0.001). Conclusion: Tailored postoperative exercise after lumbar spine surgery is effective in reducing pain and enhancing functional recovery, including strength and balance. Full article
(This article belongs to the Special Issue Innovative Perspectives in Physical Therapy and Health)
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