Search Results (3,154)

Polyethylene (PE) mulching has been widely practiced in agriculture for decades, but its short-term impacts on heavy metal dynamics and crop safety under field conditions remain poorly understood. In this study, a one-season field trial was carried out in Cd-contaminated paddy to evaluate how PE mulching influences rhizosphere microbial communities, soil physicochemical properties, and Cd accumulation in rice. Results showed that PE mulching improved rice performance, increasing dry grain weight by 14.47% and thousand-grain weight by 1.10 folds, while reducing grain Cd concentration from 0.2307 to 0.1727 mg/kg, below the national safety threshold of 0.2 mg/kg. These effects were closely linked to elevated soil pH, decreased redox potential, and the enrichment of metal-reducing (Geobacteraceae, Desulfuromonadia) and sulfate-reducing (Desulfosporosinus, Methanospirillum) taxa, which promoted Cd immobilization into less bioavailable forms. A structural equation model (SEM) further confirmed that microbial abundance and Cd speciation were key factors associated with Cd uptake by rice. However, PE mulching also reduced microbial diversity and functional redundancy, disrupted co-occurrence networks, and potentially weakened rhizosphere ecosystem stability and resilience in the short term. This study provides field-based evidence that PE mulching reduces food safety risks and improves yield but destabilizes soil microbial communities, highlighting its short-term double-edged ecological effects and the need for balanced management to sustain productivity and soil health. Full article

Background/Objectives: Increasing scientific evidence supports the importance of early diagnosis of autism spectrum disorder (ASD), followed by timely intervention, in optimizing developmental trajectories. Despite these advances, achieving an early diagnosis remains challenging, and substantial delays in the diagnostic process continue to be reported worldwide. This study aimed to describe the clinical and sociodemographic characteristics associated with early referral to a telehealth parent-mediated intervention program for infants at high likelihood for ASD, under 18 months of age, with the broader goal of informing clinical services in the field of neurodevelopmental disorders. Methods: Infants were evaluated by a multidisciplinary team using standardized measures to assess autism risk, developmental functioning, adaptive behavior, and parental stress. Potential differences in age at access to the program were examined by comparing families who were referred before versus after 12 months of age. Results: Of the 78 families who expressed interest in the program, 69 consented and 60 met eligibility criteria (male/female ratio = 40/20; mean age = 10.0 months). Families were evenly distributed across Italy, and 66% of parents held a university degree. Self-referral accounted for 62% of cases. Higher parental concern was associated with earlier referral and children referred after 12 months of age showed significantly lower developmental and adaptive functioning scores. Conclusions: These findings support the feasibility of identifying prodromes of autism within the first year of life and highlight gaps in specialized services for infants at elevated likelihood in Italy. Maternal concern and self-referral drove early consultation, underscoring the need for improved pediatric training. Future studies should assess longitudinal population-based screening and the feasibility and long-term impact of timely interventions in routine care. Full article

The widespread use of antibiotics has taken a heavy toll on the environment, which cannot be ignored. Tetracycline antibiotics (TCs), as representative pharmaceutical contaminants, have emerged as a growing environmental concern due to their persistence and potential ecological risks. This study utilized 1,3,5-benzenetricarboxylic acid (BTC) as a functionalizing reagent to synthesize magnetic nanoparticles NiFe₂O₄-COOH. These were then combined with Zr-MOF to create the magnetic adsorbent designated as NCF@Zr-MOF (where NCF represents carboxyl-functionalized nickel ferrite). Magnetic solid-phase extraction (MSPE) technology was employed to remove two representative tetracycline antibiotics, tetracycline (TC) and chlortetracycline (CTC) from the environment. The Langmuir model fitting revealed maximum adsorption reached 190.85 and 196.32 mg/g for TC and CTC, respectively, both of which conformed to the pseudo-second-order model during the adsorption process with spontaneous, heat-absorbing and entropy-increasing properties. Furthermore, following five cycles of adsorption and desorption, the removal rate for TCs was found to have decreased by 30%, yet the removal of CTCs remained at 95.32%. This adsorbent enables rapid separation via an external magnetic field. With its excellent stability and reusability, NCF@Zr-MOF shows great potential for removing antibiotics from water. Full article

Underwater robots demonstrate significant potential for hull biofouling removal. However, achieving uniform and damage-free cleaning remains a persistent challenge. The fixed arrangement of cleaning mechanisms, combined with the inherent non-uniformity of cavitation jet energy distribution, frequently results in inconsistent removal depths, leading to local over-cleaning or under-cleaning. To address this, this paper proposes an optimization framework to coordinate the robot’s motion with its cleaning mechanism. First, the flow field dynamics of the cavitation nozzle are elucidated using the Stress-Blended Eddy Simulation (SBES) turbulence model. Based on the Computational Fluid Dynamic (CFD) data, a Gaussian mapping model is constructed to quantify the relationship between jet erosion efficiency and robotic motion parameters. Furthermore, to resolve the multi-objective coverage parameter optimization problem, an improved hybrid metaheuristic algorithm—the Composite Cycloid Subtraction-Average-Based Optimizer (CCSABO)—is introduced to determine the optimal synchronization of forward and lateral velocities. Numerical simulations demonstrate the framework’s robustness across various fouling thickness scenarios and nozzle parameters. Notably, the CCSABO algorithm achieves a coverage rate of 99% and minimizes the uniformity index to 0.011, demonstrating superior consistency compared to traditional PSO and GWO methods. This improvement effectively mitigates the risk of hull damage while ensuring cleaning quality. Full article

Field cancerization is a fundamental paradigm in tumorigenesis, emphasizing that carcinogenesis begins long before the appearance of clinically detectable lesions and often precedes recognizable premalignant changes. A direct manifestation of this process is the molecular dysregulation observed in the peritumoral mucosa—histologically normal-appearing tissue that nonetheless exhibits genetic and epigenetic alterations similar to those of the adjacent tumor. This review summarizes current evidence on the molecular alterations shared between tumor tissue and peritumoral mucosa in HNSCC and evaluates their potential as biomarkers for defining molecular margins and improving surgical precision. A literature search was conducted in PubMed using combinations of the keywords “peritumor,” “laryngeal”, “HNSCC,” and “field cancerization.” Studies were included if they directly compared tumor tissue with peritumoral mucosa and, preferably, a third set of distant normal control samples. Only nine studies met the inclusion criteria, highlighting the scarcity of focused research in this area. Reported biomarkers exhibiting comparable dysregulation in both tumor and peritumor tissues include MDM2, E2F2, CDKN2A/p16, ETS-1, MGMT, and multiple microRNAs (e.g., miR-21, miR-96-5p, miR-145-5p). These molecular signatures demonstrate the presence of a biologically altered field extending beyond histologically defined tumor margins. Peritumoral mucosal dysregulation, as a consequence of field cancerization, underscores the need to redefine surgical margins at the molecular level. The identification and validation of biomarkers reflecting this continuum could enable the establishment of molecular margins—improving risk assessment, reducing local recurrence, and advancing personalized oncologic surgery in HNSCC. Standardizing definitions and sampling protocols for “normal adjacent tissue” remains essential for future translational research. Full article

The deposition of airborne microplastics (MPs) poses potential risks to human health and terrestrial ecosystems. Therefore, suitable mitigation efforts are needed, as is knowledge of their deposition patterns in inhabited and remote regions. Currently, there are no standardized protocols for monitoring airborne MPs, and implementing and managing automatic monitoring systems would be costly and feasible only in a few fixed locations. Over the past few decades, several species of cryptogams have proven to be reliable biomonitors of persistent atmospheric contaminants. Due to the lack of standardized methodologies, the results of preliminary biomonitoring surveys for MPs have been inconsistent and difficult to compare. However, they clearly indicate higher MP concentrations in epigeic mosses than in epiphytic lichens (collected at the same site or experimentally exposed in parallel in bags). This review discusses the morphophysiological features that favor the entrapment and retention of intercepted MPs in mosses, as well as the field and laboratory activities necessary to determine whether these organisms progressively accumulate airborne MPs as a function of the exposure time. Steps for future research needed to develop a cost-effective, reliable and easily applicable biomonitoring methodology are suggested. Evaluating the advantages of active moss biomonitoring over sampling atmospheric bulk deposition or exposing suitable commercial materials is recommended. Full article

The continuous detection of emerging pollutants (EPs) in water poses potential threats to aquatic environmental safety and human health, and their efficient removal is a frontier in environmental engineering research. This review systematically summarizes research progress from 2005 to 2025 on the application of activated carbon (AC) and its composites for removing EPs from water and analyzes the development trends in this field using bibliometric methods. The results indicate that research has evolved from the traditional use of AC for adsorption to the design of novel materials through physical and chemical modifications, as well as composites with metal oxides, carbon-based nanomaterials, and other functional components, achieving high adsorption capacity, selective recognition, and catalytic degradation capabilities. Although AC-based materials demonstrate considerable potential, their large-scale application still faces challenges such as cost control, adaptability to complex water matrices, material regeneration, and potential environmental risks. Future research should focus on precise material design, process integration, and comprehensive life-cycle sustainability assessment to advance this technology toward highly efficient, economical, and safe solutions, thereby providing practical strategies for safeguarding water resources. Full article

Unmanned ground vehicles (UGVs) in agriculture face challenges in navigating complex environments due to the presence of dynamic obstacles. This causes several practical problems including mission delays, higher energy consumption, and potential safety risks. This study addresses the challenge by shifting path planning from reactive local avoidance to proactive global optimization. To that end, it integrates aerial imagery from an unmanned aerial vehicle (UAV) to identify dynamic obstacles using a low-latency YOLOv8 detection pipeline. These are translated into georeferenced exclusion zones for the UGV. The UGV follows the optimized path while relying on a LiDAR-based reactive protocol to autonomously detect and respond to any missed obstacles. A farm management information system is used as the central coordinator. The system was tested in 30 real-field trials in a walnut orchard for two distinct scenarios with varying worker and vehicle loads. The system achieved high mission success, with the UGV completing all tasks safely, with four partial successes caused by worker detection failures under afternoon shadows. UAV energy consumption remained stable, while UGV energy and mission time increased during reactive maneuvers. Communication latency was low and consistent. This enabled timely execution of both proactive and reactive navigation protocols. In conclusion, the present UAV–UGV system ensured efficient and safe navigation, demonstrating practical applicability in real orchard conditions. Full article

Climate-induced lake expansion on the Tibetan Plateau (TP) has led to two distinct hazard types: outburst floods and passive inundation. However, the divergent driving mechanisms behind these hazards remain insufficiently understood. This study analyzes the spatiotemporal trends of 1352 non-glacial lakes (>1 km²) on the TP from 2014 to 2023 using high-resolution Gaofen-1 (GF-1) and Gaofen-2 (GF-2) imagery. By integrating geomorphic analysis with hazard mechanisms, we screened and categorized lakes prone to outburst floods and inundation using a classification and assessment framework proposed in this study. The results indicate that the net area of these lakes expanded by 2839.53 km² (6.07%), with the Inner TP Basin contributing the largest absolute area gain (1960.60 km²). We identified 21 potentially hazardous lakes (10 outburst-prone and 11 inundation-prone) and systematically categorized them by risk level. Field investigations of high-risk candidates, such as Rulei Co and Xiao Qaidam Lake, validated the accuracy of the hazard classification and risk assessment methodology. Preliminary attribution analysis further suggests that the two hazard types may be associated with distinct climatic factors. Overall, this study provides a scientific basis for disaster mitigation and lake management on the TP. Full article

The larvae and damage symptoms of Cnaphalocrocis medinalis and Cnaphalocrocis patnalis exhibit a high degree of similarity, which often leads to confusion between the two species. This has posed challenges for research on their population dynamics and the development of effective control measures. To better understand their morphological and damage characteristics, population dynamics, species identification based on COI gene fragments, and potential future distribution, a searchlight trap monitoring program was conducted for C. medinalis and its closely related species C. patnalis across four sites in Longhua, Haitang, and Yazhou districts in Hainan Province from 2021 to 2023. The MaxEnt model was utilized to predict the potential global distribution of both species, incorporating known occurrence points and climate variables. The trapping results revealed that both species reached peak abundance between April and June, with a maximum of 1500 individuals captured in May at Beishan Village, Haitang District. Interannual population fluctuations of both species generally followed a unimodal pattern. Genetic analyses revealed distinct differences in the mitochondrial COI gene fragment, confirming that C. medinalis and C. patnalis are closely related yet distinct species. The population peak of C. patnalis occurred slightly earlier than that of C. medinalis, and its field damage was more severe. Infestations during the booting to heading stages of rice significantly reduced seed-setting rates and overall yield. Model predictions indicated that large areas of southern Eurasia are suitable for the survival of both species, with precipitation during the wettest month identified as the primary environmental factor shaping their potential distributions. At present, moderately and highly suitable habitats for C. medinalis account for 2.50% and 2.27% of the global land area, respectively, whereas those for C. patnalis account for 2.85% and 1.19%. These results highlight that climate change is likely to exacerbate the damage caused by both rice leaf-roller pests, particularly the emerging threat posed by C. patnalis. Overall, this study provides a scientific basis for invasion risk assessment and the development of integrated management strategies targeting the combined impacts of C. medinalis and C. patnalis. Full article

Background/Objectives: Swimming requires precise motor control, sustained attention, and optimal cognitive–motor integration, making it an ideal model for investigating neural efficiency—the phenomenon whereby expert performers achieve optimal outcomes with reduced neural resource expenditure, operationalized as lower activation, sparser connectivity, and enhanced functional integration. This systematic review examined cognitive performance and neural adaptations in swimming athletes, investigating neuroimaging and behavioral outcomes distinguishing swimmers from non-athletes across performance levels. Methods: Following PRISMA 2020 guidelines, seven databases were searched (1999–2024) for studies examining cognitive/neural outcomes in swimmers using neuroimaging or validated assessments. A total of 24 studies (neuroimaging: n = 9; behavioral: n = 15) met the inclusion criteria. Risk of bias assessment used adapted Cochrane RoB2 and Newcastle–Ottawa Scale criteria. Results: Neuroimaging modalities included EEG (n = 4), fMRI (n = 2), TMS (n = 1), and ERP (n = 2). Key associations identified included the following: (1) Neural Efficiency: elite swimmers showed sparser upper beta connectivity (35% fewer connections, d = 0.76, p = 0.040) and enhanced alpha rhythm intensity (p ≤ 0.01); (2) Cognitive Performance: superior attention, working memory, and executive control correlated with expertise (d = 0.69–1.31), with thalamo-sensorimotor functional connectivity explaining 41% of world ranking variance (r² = 0.41, p < 0.001); (3) Attention: external focus strategies improved performance in intermediate swimmers but showed inconsistent effects in experts; (4) Mental Fatigue: impaired performance in young adult swimmers (1.2% decrement, d = 0.13) but not master swimmers (p = 0.49); (5) Genetics: COMT Val158Met polymorphism associated with performance differences (p = 0.026). Effect sizes ranged from small to large, with Cohen’s d = 0.13–1.31. Conclusions: Swimming expertise is associated with specific neural and cognitive characteristics, including efficient brain connectivity and enhanced cognitive control. However, cross-sectional designs (88% of studies) and small samples (median n = 36; all studies underpowered) preclude causal inference. The lack of spatially quantitative synthesis and visualization of neuroimaging findings represents a methodological limitation of this review and the field. The findings suggest potential applications for talent identification, training optimization, and mental health promotion through swimming but require longitudinal validation and development of standardized swimmer brain atlases before definitive recommendations. Full article

Urban flood disaster management is an interdisciplinary field that integrates hydrology, geology, engineering, and urban planning, with prediction, assessment, and optimization serving as its core components. However, a comprehensive and systematic synthesis of recent developments in this domain remains limited, constraining both theoretical understanding and practical advancement. To address this gap, this study conducts an in-depth analysis of urban flood management research as a systematic review, with a particular focus on advances in prediction, assessment, and optimization. Utilizing a multistep holistic review, combining bibliometric and scientometric analysis with structured literature categorization, the research critically examines and synthesizes relevant findings. This study analyzed 166 research papers related to urban flood management within the Web of Science database. Through co-citation and keyword co-occurrence analyses, five dominant research dimensions are identified: physics-based simulation methods, data-driven approaches, risk assessment tasks, optimization strategies, and miscellaneous emerging topics. Based on these insights, we propose a task-oriented framework that systematically integrates prediction, assessment and optimization across the four phases of disaster management: mitigation, prevention, emergency response and recovery. This framework aids scholars and practitioners in understanding and implementing effective techniques and strategies. The study’s findings shed light on key trends and potential future directions, providing a roadmap for further exploration of urban flood management and guiding professionals in related fields. Full article

In the face of increasing global temperatures, this study aims to explore ventilation strategies that could provide passive cooling to mitigate overheating in studied low-energy school buildings, in particular those that use ventilative cooling. This study utilises building modelling calibrated with field data to tackle the challenge of maintaining indoor thermal comfort and cognitive performance levels during increasingly warm seasons. The calibrated building model is used to evaluate the vulnerability of classrooms, identifying and addressing risks based on standardised overheating and resilience criteria. Two primary school classrooms were simulated in three main cities across Ireland to assess the possibility of natural ventilative cooling for maintaining indoor thermal conditions without sacrificing energy efficiency. The study highlights the critical need to enhance natural ventilation strategies to protect against projected future overheating, with peak indoor temperatures reaching 29 °C to 31 °C during May, June, and September. Implementing a maximum natural ventilation strategy during occupied times, with a 9.6% opening-to-floor area ratio, can reduce peak indoor temperatures by up to 2.5 °C. Findings show Irish classrooms in low-energy buildings equipped with hybrid ventilative cooling can act as potential climate shelters during July and August under extreme weather conditions, underlining their capacity to provide a comfortable environment for vulnerable people during heatwaves and reduce overheating risk by 42–48% compared to natural ventilation. Additionally, projections show that cognitive performance loss in students may rise to 23% by 2071 due to raised indoor temperatures; however, this can be reduced to below 10% in 2021 and 2041 with maximum natural ventilation. The novelty of this work lies in its systematic evaluation of ventilative cooling resilience under future climate scenarios across multiple Irish city contexts, providing a robust evidence base for designing climate-resilient, energy-efficient learning environments. Full article

The objectives of this work were (i) to evaluate the incidence of complications in male horses after orchiectomy performed in the field, i.e., away from a veterinary hospital, (ii) to describe the post-operative complications that occurred in these animals and (iii) to study the potential predictors for the development of such complications. This study involved 612 animals, on which orchiectomy was performed. The operative part of the study was carried out by one of three experienced veterinary surgeons. Standard pre-operative procedures were followed. Orchiectomy was performed using one of three principal surgical techniques, open, semi-closed or closed, and hemostasis was achieved by means of one of the various procedures, specifically the use of the Henderson instrument, the use of the Reimer emasculator, the ligation of the testicular artery or combinations thereof. In cases of reported complications, these were verified and identified appropriately. At least one (any) post-operative complication was recorded in 145 horses (23.7%). The most frequently observed complication was scrotal swelling/seroma formation, which was observed in 130 animals (21.2% of all animals; 89.7% of animals with at least one (any) complication). Another six different complications were observed, specifically colic, continued stallion-like behavior, evisceration, funiculitis, hemorrhage and scrotal infection. The median age of horses with complications was significantly older than that of animals with no complications: 11 versus 9 years. Animals in which the open technique was applied developed post-operative complications more frequently (30.1% of animals thus operated); further, complications were observed more frequently in animals on which operations were performed by using the Henderson instrument (84.6% of animals) versus animals on which any of the various other procedures were applied (22.4%). In multivariable analysis, the following predictors emerged for the development of complications: the surgical technique employed, the procedure applied for hemostasis, older animal age, and heavier animal bodyweight. The findings confirm that orchiectomy in stallions, even when performed in field conditions, is, in general, a safe procedure. The identification of predictors suggests that veterinarians should take additional care when planning to operate on animals at higher risk or when using surgical approaches that increase the potential for the development of complications. Full article

Background: The Rohingya refugee crisis is one of the largest humanitarian emergencies of the 21st century, with nearly one million Rohingya residing in overcrowded camps in southern Bangladesh. Women and children face the greatest vulnerabilities, including inadequate access to education and healthcare, which exacerbates their risks and limits opportunities for personal and community development. While international organizations continue to provide aid, resources remain insufficient, particularly in maternal and child healthcare, highlighting the urgent need for sustainable interventions. Objectives: The Hope Foundation for Women and Children in Bangladesh launched a pilot project for the Health Assistant Training (HAT) program to address critical gaps in healthcare and education for the Rohingya community. This nine-month training program equips young Rohingya women with essential knowledge and skills to support maternal health services in both clinical and community settings. Design: We conducted a qualitative evaluation of the HAT Program to explore its acceptance and anticipated benefits for both participants and the community. Methods: The research team used semi-structured interviews, focus groups, and field observations to explore the HAT Program’s impact on young Rohingya women and their community. They analyzed data through thematic analysis, developing a coding framework and identifying key themes to uncover patterns and insights. Results: The results were categorized into four themes: (1) community acceptance of the HAT Program, (2) the HAT Program’s impact on the health assistant trainees, (3) the impact of the HAT Program on the community, and (4) the potential ways to expand the HAT Program. Conclusions: This research underscores the program’s impact on improving healthcare access, enhancing women’s empowerment, and promoting community resilience. By situating this initiative within the broader context of refugee health, education, and capacity-building, this research highlights the HAT program’s potential as a replicable model in Bangladesh and in other humanitarian settings. Full article