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26 pages, 572 KB  
Article
Financing Post-War Circular Reconstruction: Digital Tools and Investment Pathways for Ukraine’s Industrial Regions
by Tetiana Gorokhova and Žaneta Simanavičienė
J. Risk Financial Manag. 2026, 19(4), 293; https://doi.org/10.3390/jrfm19040293 - 18 Apr 2026
Viewed by 408
Abstract
Ukraine’s reconstruction, estimated at $524 billion over the next decade, presents an unprecedented opportunity to embed circular economy principles into industrial rebuilding, but the financial architecture currently deployed for reconstruction is structurally blind to circular outcomes. This paper examines how digital tools and [...] Read more.
Ukraine’s reconstruction, estimated at $524 billion over the next decade, presents an unprecedented opportunity to embed circular economy principles into industrial rebuilding, but the financial architecture currently deployed for reconstruction is structurally blind to circular outcomes. This paper examines how digital tools and innovative financing mechanisms can channel investment toward circular industrial reconstruction in Ukraine, drawing on Germany’s National Circular Economy Strategy (NCES, adopted December 2024) as a reference model. A comparative institutional analysis combines a documentary review of Ukrainian reconstruction policy frameworks (Ukraine Plan 2024–2027, RDNA4, Ukraine Facility) and German NCES instruments with the construction of a financing−technology pathway typology. Five pathways are proposed: circular bond issuance with Digital Product Passport integration; blended finance with blockchain impact verification; EU Facility conditionality with AI-driven resource management; war risk insurance with circular construction standards; and SME digitalisation credit with circular economy competency building. Each pathway is assessed against five criteria: investment scale, risk mitigation, circular measurement, digital readiness, and institutional feasibility, and applied to four industrial corridors (Dnipro region, Zaporizhzhia region, Kharkiv region, and Donetsk region). The analysis reveals that no single pathway is sufficient; a layered strategy differentiating by region is required. Digital tools, particularly the Digital Product Passport and blockchain traceability, serve as partial substitutes for institutional trust in post-conflict settings, reducing information asymmetry between investors and project operators. The paper contributes a practically oriented framework at the under-theorised intersection of post-conflict reconstruction finance and circular economy scholarship. Full article
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24 pages, 3356 KB  
Article
The Attention Mismatch: Mapping the Structural Academic Governance Deficit in the Age of Generative AI
by Zhenning Guo, Haoran Mao and Fang Zhang
Publications 2026, 14(2), 27; https://doi.org/10.3390/publications14020027 - 17 Apr 2026
Viewed by 310
Abstract
With the rapid advancement in Generative Artificial Intelligence (GenAI), AI-generated content (AIGC) lacking human cognitive oversight is increasingly permeating open web environments and academic communication systems. This study integrates longitudinal retraction data (Retraction Watch Database, 1990–2026), web-scale analyses of AI-content penetration (Common Crawl, [...] Read more.
With the rapid advancement in Generative Artificial Intelligence (GenAI), AI-generated content (AIGC) lacking human cognitive oversight is increasingly permeating open web environments and academic communication systems. This study integrates longitudinal retraction data (Retraction Watch Database, 1990–2026), web-scale analyses of AI-content penetration (Common Crawl, 2013–2026), and bibliometric mapping of governance scholarship (Web of Science Core Collection, Scopus, Google Scholar, 2020–2026) to diagnose the cross-level misalignment between synthetic-content diffusion, AI-related misconduct pressure, and governance attention. On this basis, it proposes a Normalized Coverage Index (NCI) to measure the relative relationship between scholarly attention to AI-related academic misconduct governance and the level of misconduct pressure observed through retraction data across disciplines. The results reveal pronounced asymmetries at the disciplinary level. Fields such as chemistry (0.04), physics, mathematics & statistics (0.11), and life sciences & biology (0.34) exhibit clear governance gaps, whereas Education shows a comparatively excessive level of attention (NCI = 29.26). Since 2022, AIGC has expanded rapidly across open web corpora, accompanied by a sharp rise in AI-related retractions, which also exhibit a longer detection lag than traditional forms of misconduct (2.77 years vs. 1.91 years). Although the volume of academic governance-related research has grown rapidly, its proportion within the broader body of AI-related research has declined, suggesting that scholarly attention to governance has not kept pace with technological diffusion. Consequently, a structural misalignment in governance—closely tied to the allocation of attention—has emerged within the academic system in the era of GenAI. This misalignment may pose potential risks to the robustness of the knowledge production system. Addressing it requires rebuilding epistemic infrastructure through provenance transparency, auditable workflows, and governance-aware seed corpora aligned with empirically concentrated risks. Full article
(This article belongs to the Special Issue Large Language Models Across the Lifecycle of Scholarly Publishing)
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8 pages, 455 KB  
Commentary
Over Two Million Life-Years at Risk: Why Gaza’s Health Reconstruction Is a Moral Imperative
by Alessandro Vitale, Mohammad Abu Hilal, Umberto Cillo, Isabella Frigerio and Andrew A. Gumbs
Int. J. Environ. Res. Public Health 2026, 23(4), 484; https://doi.org/10.3390/ijerph23040484 - 12 Apr 2026
Viewed by 440
Abstract
The concept of “Healthocide,” first defined by Abi-Rached and colleagues, describes the deliberate and systematic destruction of health systems as a weapon of war. Nowhere is this phenomenon more extensively documented than in Gaza, where the collapse of healthcare infrastructure since October 2023 [...] Read more.
The concept of “Healthocide,” first defined by Abi-Rached and colleagues, describes the deliberate and systematic destruction of health systems as a weapon of war. Nowhere is this phenomenon more extensively documented than in Gaza, where the collapse of healthcare infrastructure since October 2023 has been rapid, wide-ranging, and intentionally sustained. The consequence is not only immediate excess mortality, but also profound, long-term loss of population health measured in life-years, a metric that captures both premature death and reductions in expected lifespan. To address the aftermath of such destruction, we propose the framework of “Healthogenesis,” defined as a Palestinian-led, equity-driven, and rights-anchored approach to health system reconstruction in which international actors serve as enablers rather than agenda-setters. The aim of Healthogenesis is not merely to restore pre-war capacity, but to build a resilient, sovereign, and future-proof health ecosystem. Using available demographic and mortality data, we estimate that more than three million life-years have already been lost in Gaza since October 2023. Projection models suggest that an additional 1.1 to 2.2 million life-years could be lost over the coming decade unless an organized programme of reconstruction begins immediately. Quantifying harm in life-years reframes the discourse from moral outrage to measurable obligation. If Healthocide names the crime, then Healthogenesis outlines the cure: a coherent, data-anchored, ethically grounded roadmap for rebuilding a devastated health system and protecting the health futures of an entire population. Full article
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26 pages, 371 KB  
Article
Attitudes Toward Sexual and Digital Consent and Institutional Distrust as Determinants of Gender-Based Violence Prevention: Evidence from an Urban Adult Population
by Esperanza García Uceda, Diana Valero Errazu and Jesús C. Aguerri
Int. J. Environ. Res. Public Health 2026, 23(4), 480; https://doi.org/10.3390/ijerph23040480 - 10 Apr 2026
Viewed by 427
Abstract
Gender-based and sexual violence are major public health concerns, and norms about consent are central to their prevention. This study examines how attitudes toward sexual consent relate to digital sexual consent and to the occasional feeling of distrust in public consent campaigns and [...] Read more.
Gender-based and sexual violence are major public health concerns, and norms about consent are central to their prevention. This study examines how attitudes toward sexual consent relate to digital sexual consent and to the occasional feeling of distrust in public consent campaigns and institutions. We conducted a cross-sectional online survey embedded in the evaluation of a municipal consent campaign in Zaragoza (Spain). Adults (N = 404; 56.7% women) completed a 14-item short version of the Sexual Consent Scale–Revised, two items on digital sexual consent, and three items on institutional reluctance (perceived “sermonizing” tone, distrust in effectiveness, and lack of personal identification with the message). Correlation and multiple regression models with robust standard errors were estimated, controlling for gender, age, education, income, relationship status, and social media use. Attitudes toward sexual consent were strongly and positively associated with digital sexual consent. Gender was the most consistent sociodemographic correlate: men showed less egalitarian attitudes than women across all consent measurements. Institutional reluctance was systematically related to less supportive consent attitudes: perceiving institutional messages as exaggerated or personally irrelevant predicted lower support for sexual and digital consent norms, whereas trust in the campaign’s effectiveness was associated with more egalitarian attitudes. The findings support the continuity between sexual and digital consent and highlight gender and institutional trust as key determinants for the prevention of gender-based and sexual violence. Public health and social policies should integrate digital consent into consent education and co-design campaigns that minimize defensive reactions and rebuild trust in institutions. Full article
21 pages, 973 KB  
Article
ViTUNet: Vision Transformer U-Net Hybrid Model for Carious Lesions Segmentation on Bitewing Dental Images
by Vincent Majanga, Ernest Mnkandla, Ekundayo Olufisayo Sunday, Bosun Ajala and Thottempundi Sree
Appl. Sci. 2026, 16(8), 3693; https://doi.org/10.3390/app16083693 - 9 Apr 2026
Viewed by 190
Abstract
Meticulous segmentation of medical images requires obtaining both local and global spatial detailed information. The conventional U-Net model excels at local spatial feature extraction through residual convolutional blocks but struggles to capture global features. To resolve this issue, we propose the vision transformer [...] Read more.
Meticulous segmentation of medical images requires obtaining both local and global spatial detailed information. The conventional U-Net model excels at local spatial feature extraction through residual convolutional blocks but struggles to capture global features. To resolve this issue, we propose the vision transformer U-NeT (ViTUNet) model framework, which combines the self-attention mechanism of the vision transformer (ViT) to capture global information while maintaining the extraction of local features via U-NeT. This proposed architecture introduces vision transformers to the existing residual convolution blocks in the U-Net encoder path, thereby capturing both local and global features. The decoder path then rebuilds this information into high-quality segmentation maps with accurately highlighted boundaries/edges. This model is utilized to segment carious lesions in bitewing dental radiographs. These images are pre-processed using augmentation, morphological operations, and segmentation to identify the boundaries/edges of the regions of interest (caries/cavity). The proposed method is evaluated on an augmented dataset containing 3000 image–watershed mask pairs. It was trained on 2400 training images and tested on 600 testing images. The experimental results exemplified significant improvements in segmentation performance, achieving 98.45% validation accuracy, 97.88% validation Dice coefficient, and 95.87% validation intersection over union (IoU) metric scores. These results are superior compared to other conventional and state-of-the-art U-NeT models, thus highlighting the impact of transformer-based hybrid architectures in improving medical image segmentation tasks. Full article
(This article belongs to the Special Issue Advances in Medical Physics and Quantitative Imaging)
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26 pages, 4951 KB  
Article
An Exploratory Application of Low-Cost Drone Imagery and an Image Analysis Model to Evaluate Post-Disaster Recovery Progress for Planning Equitable Housing Recoveries Through Dynamic Funding Allocation
by Daniel V. Perrucci, German C. Buitrago, Brady McKay, Kathleen Short and Christopher Santos
Urban Sci. 2026, 10(4), 199; https://doi.org/10.3390/urbansci10040199 - 3 Apr 2026
Viewed by 412
Abstract
After major disruptive events, particularly natural and human-made disasters, community leaders face the challenge of rebuilding societal infrastructure and managing the allocation of funds, which can affect the duration of recovery periods. Decision-makers must quickly determine how to allocate financial resources while minimizing [...] Read more.
After major disruptive events, particularly natural and human-made disasters, community leaders face the challenge of rebuilding societal infrastructure and managing the allocation of funds, which can affect the duration of recovery periods. Decision-makers must quickly determine how to allocate financial resources while minimizing population distress. Conventional methods of assessing damage and evaluating relief requirements fall short of meeting the urgent recovery needs after a disaster, potentially leading to negative effects on communities, such as involuntary relocation and neighborhood gentrification. The study evaluates current methods and technologies to propose a new approach that leverages low-cost consumer drones and modern image analysis techniques to support initial damage assessments and track recovery progress, thereby promoting the dynamic allocation of limited resources. Using low-cost drone imagery enables rapid, cost-effective data collection and dynamic analysis through iterative reviews during the disaster response and recovery phases that can adjust baseline disaster funding allocations. The study investigates the potential of temporary blue tarp roofs (“blue roofs”) as a metric for recovery progress during the 2020 tornado in Middle Tennessee and conducts an R-squared and error analysis. The goal of this research is to evaluate an affordable and efficient data analysis method (e.g., modern image analysis; artificial intelligence; low-cost drones) that can improve post-disaster resource allocation and inform decision-making for governmental and planning officials. Full article
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13 pages, 263 KB  
Article
Expectations, Credibility, and the Persistence of Currency Substitution
by Mohammad Alawin
Int. J. Financial Stud. 2026, 14(4), 89; https://doi.org/10.3390/ijfs14040089 - 3 Apr 2026
Viewed by 245
Abstract
This study examines why currency substitution proves so difficult to reverse, even after countries succeed in stabilizing inflation. Focusing on Bolivia, Brazil, Mexico, and Turkey—economies that endured severe inflationary episodes before implementing stabilization programs—the paper asks a simple but important question: why does [...] Read more.
This study examines why currency substitution proves so difficult to reverse, even after countries succeed in stabilizing inflation. Focusing on Bolivia, Brazil, Mexico, and Turkey—economies that endured severe inflationary episodes before implementing stabilization programs—the paper asks a simple but important question: why does reliance on foreign currency persist long after inflation has been brought down? To answer this, the analysis adopts a structural time-series state-space framework that allows behavioral parameters to evolve gradually over time. Rather than assuming persistence, the model lets it emerge from the data and, crucially, compares alternative ways in which agents might form expectations about exchange rate movements. The evidence reveals a consistent pattern. By the end of the sample period, currency substitution remains statistically and economically significant in all four countries. The dominant expectation mechanism is extrapolative: agents tend to look at recent depreciation and assume it will continue. This tendency creates a reinforcing loop—when currencies depreciate, expectations of further depreciation strengthen, and the incentive to hold foreign currency intensifies. What makes these findings particularly striking is that this dynamic does not vanish once inflation is stabilized. Even in periods of relative macroeconomic calm, substitution persists. Past instability leaves a lasting imprint on expectations, and concerns about the durability of policy reforms continue to shape monetary behavior. In several cases, ongoing depreciation against the U.S. dollar further validates these cautious beliefs. As a result, the findings suggest that currency substitution is not merely a mechanical residue of past inflation. It is sustained by the way people form and update expectations in environments marked by credibility challenges. Stabilizing inflation is therefore a necessary step, but it is not enough on its own. Durable confidence in the domestic currency requires rebuilding credibility in a way that gradually reshapes expectations and restores trust over time. Full article
22 pages, 1570 KB  
Article
Sustainable Rheology of Clay–Cement–Fly Ash Sealing Suspensions Applicable in Hydrotechnical Construction
by Jurij Delihowksi, Paweł Pichniarczyk, Filippo Gobbin, Paolo Colombo and Piotr Izak
Appl. Sci. 2026, 16(7), 3481; https://doi.org/10.3390/app16073481 - 2 Apr 2026
Viewed by 434
Abstract
The development of eco-efficient construction materials requires optimisation strategies that reduce cement consumption, valorise industrial by-products, and enhance performance without increasing material demand. Clay–cement sealing suspensions used in geotechnical engineering offer significant sustainability potential due to their high mineral content and compatibility with [...] Read more.
The development of eco-efficient construction materials requires optimisation strategies that reduce cement consumption, valorise industrial by-products, and enhance performance without increasing material demand. Clay–cement sealing suspensions used in geotechnical engineering offer significant sustainability potential due to their high mineral content and compatibility with supplementary cementitious materials such as siliceous fly ash. The early-age rheological properties are essential for the design of geotechnical sealing barriers, yet the influence of chemical additive sequencing on flow behaviour remains poorly understood. This study examines how the priority of sodium silicate addition—introduced either before cement and siliceous fly ash (the “Prior” series) or after them (the “After” series)—affects the flow curves, yield stress, thixotropy, and equilibrium shear stress of clay–cement–fly ash sealing suspensions. Ascending flow curves were fitted to the Casson, Herschel–Bulkley, and Ostwald–de Waele models, and a shear-rate-resolved thixotropic power density analysis was applied to decompose the hysteresis behaviour. The results demonstrate that the Prior series produces deflocculated colloidal clay networks with localised cementitious agglomerates, exhibiting lower shear stresses at low shear rates but markedly higher yield stress amplitudes and larger hysteresis loop areas. The After series yields more uniformly distributed nucleation–coagulation networks with smaller hysteresis loops and pronounced structural rebuilding at low shear rates during the ramp-down phase. These findings provide a physicochemical framework for tailoring the early-age rheology of clay–cement suspensions through controlled additive sequencing, with direct implications for pumpability, injectability, and post-placement structural recovery in geotechnical applications. Full article
(This article belongs to the Special Issue Eco-Friendly Building Materials Made from Industrial Waste)
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27 pages, 2020 KB  
Article
A Lightweight Python Recovery Tool for Waveform Gap Recovery in Seismic–Volcanic Monitoring Networks
by Santiago Arrais, Paola Nazate-Burgos, Nathaly Orozco Garzón, Ángel Leonardo Valdivieso Caraguay and Luis Urquiza-Aguiar
Technologies 2026, 14(4), 211; https://doi.org/10.3390/technologies14040211 - 2 Apr 2026
Viewed by 433
Abstract
Seismic–volcanic monitoring networks often operate in remote areas over heterogeneous links (e.g., microwave radio and cellular). During event-driven seismic episodes, sustained multi-station waveform streams can stress both last-mile connectivity and data acquisition systems, yielding discontinuities in center-side archives even when stations keep recording [...] Read more.
Seismic–volcanic monitoring networks often operate in remote areas over heterogeneous links (e.g., microwave radio and cellular). During event-driven seismic episodes, sustained multi-station waveform streams can stress both last-mile connectivity and data acquisition systems, yielding discontinuities in center-side archives even when stations keep recording locally. This paper presents the Python Recovery Tool (PRT), a lightweight command-line artifact that retrieves buffered waveform files after reconnection and rebuilds daily archives that can be ingested by the monitoring center without hardware upgrades. PRT detects archive gaps from daily (Julian day) file partitions and embedded timestamps, and reduces recovery traffic by selectively fetching only the files needed to backfill missing intervals. We evaluated PRT on five event-driven recovery cases using operational file-based evidence from station and center listings complemented with a simple bandwidth-based recovery-time model. Across the cases, PRT restored archive continuity while reducing download volume by 4.43–93.75% relative to naive bulk retrieval, with modeled catch-up times ranging from 0.79 to 207.59 min, depending on station-side packaging granularity and bottleneck link capacity. These results support a practical retrofit path to improve archive completeness under constrained links and heterogeneous deployments. Full article
(This article belongs to the Section Information and Communication Technologies)
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37 pages, 3168 KB  
Review
Advances in Nanotechnology-Assisted Delivery of TCM-Derived Bioactive Compounds for Wound Repair
by Lu Ren, Zefeng Zhao, Tianzihan Zhang, Meiting Kou, Xiaozhen Ma, Jiajun Li, Mengchen Lei and Haifa Qiao
Pharmaceutics 2026, 18(4), 427; https://doi.org/10.3390/pharmaceutics18040427 - 30 Mar 2026
Viewed by 701
Abstract
Healing skin wounds is still difficult in many clinical situations, especially when the wounds are chronic or infected. These wounds often stay inflamed for long periods, and the risk of bacterial invasion is high. Oxidative stress tends to increase as well, while the [...] Read more.
Healing skin wounds is still difficult in many clinical situations, especially when the wounds are chronic or infected. These wounds often stay inflamed for long periods, and the risk of bacterial invasion is high. Oxidative stress tends to increase as well, while the formation of new blood vessels is often inadequate. Because of these factors, wound repair depends on the proper coordination of several biological events. These include basic antimicrobial activities, the control and resolution of inflammation, protection against oxidative damage, the rebuilding of collagen structures, and the development of new vascular networks. Traditional Chinese Medicine (TCM) provides many active compounds. These compounds work on many targets and through different pathways. They show good potential in wound treatment. But many TCM compounds have poor solubility in water. They are also unstable, have low bioavailability, and do not pass through the skin easily. These problems limit their use in clinical settings. Nanotechnology offers new ways to solve these problems. Nanodelivery systems can improve the solubility and stability of active compounds. They can also help the compounds enter the skin and stay in the wound area. Many types of nanocarriers have been developed, such as liposomes, polymer nanoparticles, nanogels, and inorganic nanomaterials. These systems can also provide controlled release or release that responds to the wound environment. This can make the treatment more accurate. In this review, we summarize how major TCM-derived compounds support wound repair and describe the biological mechanisms behind their effects. We also discuss recent nanodelivery approaches that aim to strengthen these therapeutic actions. These combinations can improve antibacterial performance, shape the immune response, reduce reactive oxygen species, and help the skin close more quickly. We also point out several challenges, such as concerns about material safety, the need for more consistent herbal extraction methods, gaps in mechanistic understanding, and the difficulty of producing these formulations on a large scale. Taken together, these points suggest that nanodelivery approaches using TCM-derived compounds still need more careful study and steady improvement before they can be used more widely in wound care. Full article
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16 pages, 322 KB  
Article
Daisaku Ikeda’s Philosophy and Practice of Interfaith Dialogue and the UN Sustainable Development Goals (SDGs): Human Revolution and Pathways to Global Peace
by Chang-Eon Lee
Religions 2026, 17(3), 375; https://doi.org/10.3390/rel17030375 - 17 Mar 2026
Viewed by 316
Abstract
This paper examines the philosophy and practice of interfaith dialogue (IFD) developed by Daisaku Ikeda (1928–2023), a prominent religious leader and peace philosopher. It explores how his dialogical approach can contribute to the United Nations’ Sustainable Development Goals (SDGs) and pathways to global [...] Read more.
This paper examines the philosophy and practice of interfaith dialogue (IFD) developed by Daisaku Ikeda (1928–2023), a prominent religious leader and peace philosopher. It explores how his dialogical approach can contribute to the United Nations’ Sustainable Development Goals (SDGs) and pathways to global peace. Ikeda’s dialogue is not confined to doctrinal debate or temporary reconciliation among faith communities. Rather, it is framed as a transformative process in which participants from diverse religious and civilizational traditions rebuild relationships through mutual respect and understanding, thereby contributing to personal transformation and broader societal change. Focusing on Ikeda’s core concepts—humanism, the dignity of life, and human revolution—this study first clarifies the philosophical foundations of his interfaith dialogue rooted in Nichiren Buddhism and a life-affirming worldview. It then examines major dialogues with global thinkers and leaders (e.g., Arnold J. Toynbee, Linus Pauling, Mikhail Gorbachev, and Johan Galtung) and selected institutional practices associated with Soka Gakkai International (SGI), the Institute of Oriental Philosophy (IOP), and the Ikeda Center for Peace, Learning, and Dialogue. These cases illustrate how Ikeda’s IFD functions as praxis for civilizational understanding, social cohesion, conflict transformation, and solidarity for the public good. The paper further analyzes the linkages between Ikeda’s IFD and SDG 16 (Peace, Justice and Strong Institutions), SDG 17 (Partnerships for the Goals), SDG 4 (Quality Education—especially Target 4.7 on Global Citizenship Education), and SDG 10 (Reduced Inequalities). It argues that IFD can operate as both a normative and practical resource for mitigating religious conflict, strengthening inclusion, enhancing global citizenship education and education for sustainable development (ESD), and fostering multistakeholder partnerships. The paper also reflects on the challenges of translating an approach grounded in a particular religious tradition into broader SDG governance contexts. Full article
42 pages, 2233 KB  
Review
Nanobiotechnology-Based Strategies for Targeting Neuroinflammation and Neural Tissue Engineering
by Tejas Yuvaraj Suryawanshi, Neha Redkar, Akanksha Sharma, Jyotsna Mishra, Sumit Saxena and Shobha Shukla
Immuno 2026, 6(1), 18; https://doi.org/10.3390/immuno6010018 - 13 Mar 2026
Viewed by 875
Abstract
Neuroinflammation is a central hallmark of numerous neurological disorders, including Alzheimer’s disease, Parkinson’s disease, traumatic brain injury, and spinal cord damage. Its persistent and dysregulated nature not only accelerates neuronal loss but also impedes endogenous repair, posing a major challenge for effective therapeutic [...] Read more.
Neuroinflammation is a central hallmark of numerous neurological disorders, including Alzheimer’s disease, Parkinson’s disease, traumatic brain injury, and spinal cord damage. Its persistent and dysregulated nature not only accelerates neuronal loss but also impedes endogenous repair, posing a major challenge for effective therapeutic intervention. Recent advances in nanobiotechnology have opened transformative opportunities to modulate neuroinflammation with unprecedented precision while simultaneously supporting neural regeneration. This review highlights emerging nanomaterial-based strategies including lipid-based, polymeric, inorganic nanoparticles designed to traverse the blood–brain barrier (BBB), deliver anti-inflammatory agents, modulate immune cell behavior, and attenuate glial activation. Extending beyond nanoparticle-based delivery systems, recent advances also emphasize the integration of nanomaterials into biomimetic architectures to provide structural and functional cues for neural repair. We further summarize how these functional nanostructured scaffolds, such as extracellular matrix (ECM) mimetic, nanofibrous and conductive hydrogels, are being leveraged in neural tissue engineering to direct stem cell fate, promote axonal outgrowth, and rebuild damaged neuroarchitectures. Moreover, pharmacokinetics, biodistribution, safety, clinical trials, regulatory considerations and limitations of nanotherapeutics in neurodegenerative diseases are discussed. By outlining the current progress, mechanistic insights, and translational challenges, this review underscores the potential of nanobiotechnology-enabled therapeutics to revolutionize the treatment of neuroinflammatory conditions and advance next-generation neural repair technologies. Full article
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17 pages, 505 KB  
Review
Potential of PGPR to Enhance Soybean Productivity in Europe
by Anna Kolanoś, Katarzyna Panasiewicz, Agnieszka Faligowska, Grażyna Szymańska and Karolina Ratajczak
Agriculture 2026, 16(5), 497; https://doi.org/10.3390/agriculture16050497 - 25 Feb 2026
Cited by 1 | Viewed by 673
Abstract
Soybean cultivation in Europe remains limited compared to major global producing regions, resulting in dependence on imported sources of plant protein. Although soybean cultivation has expanded in several European countries in recent years, production is still constrained by climatic variability, soil conditions, restricted [...] Read more.
Soybean cultivation in Europe remains limited compared to major global producing regions, resulting in dependence on imported sources of plant protein. Although soybean cultivation has expanded in several European countries in recent years, production is still constrained by climatic variability, soil conditions, restricted availability of locally adapted varieties, and yield instability. To improve the stimulation of plant defense mechanisms against biotic and abiotic stress, and above all, to achieve yield stability, there is an increasing search for environmentally friendly products, such as biofertilizers, that can be used to rebuild and maintain a sustainable ecosystem. However, environmental intervention requires extensive research on plant species and bacteria. Therefore, increasing attention is being focused on plant growth-promoting rhizobacteria (PGPR), among other factors. These microorganisms stimulate the growth of their host through various pathways, enabling biomass growth, and improving vitality. In the near future, this may explain the various detailed mechanisms of their interactions with plants. This article reviews the current state of soybean production in Europe and synthesizes recent advances in the understanding of PGPR–soybean interactions, with particular emphasis on both direct and indirect mechanisms of action. The roles of PGPR in nutrient acquisition, phytohormone modulation, biological nitrogen fixation efficiency, and stress tolerance are discussed alongside their capacity to suppress soil-borne pathogens and induce systemic resistance. Furthermore, recent European field and greenhouse studies evaluating seed and soil inoculation strategies are summarized to highlight region-specific responses under diverse agroecological conditions. Collectively, the available evidence indicates that PGPR application can contribute to improved soybean performance in Europe, although its effectiveness remains strongly dependent on environmental factors, strain selection, and crop management practices. Full article
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10 pages, 251 KB  
Article
Reconstructing the Great Caliphate [Kanem-Bornu Empire]: Religious War or Mere Scramble for Resources? The Appropriate Response of Religious Institutions, Civil Societies, and States
by Jean Olivier Nke Ongono
Religions 2026, 17(3), 281; https://doi.org/10.3390/rel17030281 - 25 Feb 2026
Viewed by 588
Abstract
The Boko Haram insurgency, which began in the early 2000s with the openly declared intention of rebuilding the historically renowned Muslim Kanem-Bornu kingdom, which covered northern Nigeria, northern Cameroon, parts of Niger, Chad, and Libya for centuries, has caused widespread death and suffering. [...] Read more.
The Boko Haram insurgency, which began in the early 2000s with the openly declared intention of rebuilding the historically renowned Muslim Kanem-Bornu kingdom, which covered northern Nigeria, northern Cameroon, parts of Niger, Chad, and Libya for centuries, has caused widespread death and suffering. This paper questions the authenticity and feasibility of such a project in the context of the region’s current religious landscape and discusses how religious institutions, civil societies, and states should respond. Full article
(This article belongs to the Special Issue The Ethics of War and Peace: Religious Traditions in Dialogue)
25 pages, 19199 KB  
Article
Spatiotemporal Evolution of Groundwater System Sustainability in Northeast China’s Transboundary River Basins Under Agricultural Expansion and Climate Variability: Insights from GRACE Satellite Observations
by Yujia Liu, Yang Liu, Kaiwen Zhang and Changlei Dai
Hydrology 2026, 13(2), 69; https://doi.org/10.3390/hydrology13020069 - 11 Feb 2026
Viewed by 923
Abstract
Groundwater is a critical strategic resource supporting agricultural production and ecological security in the transboundary river basins of Northeast China. However, intensified climate variability and rapid agricultural expansion over the past two decades have imposed increasing pressure on regional groundwater systems. In this [...] Read more.
Groundwater is a critical strategic resource supporting agricultural production and ecological security in the transboundary river basins of Northeast China. However, intensified climate variability and rapid agricultural expansion over the past two decades have imposed increasing pressure on regional groundwater systems. In this study, we integrated GRACE-derived terrestrial water storage anomalies, GLDAS land surface data, meteorological datasets, land-use information, and agricultural statistics to construct a comprehensive assessment framework consisting of groundwater storage anomalies (ΔGWS), the GRACE Groundwater Drought Index (GGDI), and sustainability indicators—REL (Reliability), RES (Resilience), VUL (Vulnerability), and SI (Sustainability Index). By integrating GRACE-derived groundwater dynamics with sustainability indicators (REL, RES, VUL, and SI), enabling a basin-scale, long-term assessment of groundwater sustainability across Northeast China’s transboundary basins, and clarifying the relative roles of climatic variability and intensive human water use. We systematically examined the spatiotemporal evolution of groundwater conditions in the Heilongjiang, Suifen, Tumen, and Yalu River basins from 2002 to 2022, and quantified the relative roles of climatic and anthropogenic drivers. The results indicate that groundwater storage exhibited pronounced seasonal fluctuations alongside a persistent downward trend, with GGDI remaining predominantly negative after 2018, reflecting the development of structural groundwater drought. The SI declined markedly from 0.32 to 0.06, and areas with extremely low sustainability accounted for more than 90% of the study region in recent years. MIC-based dependence analysis showed that sown area (MIC = 0.98) and nighttime light intensity (MIC = 0.92) were the dominant drivers of groundwater degradation, exerting far greater influence than precipitation or potential evapotranspiration. These patterns highlight that policy-driven agricultural expansion and increased irrigation demand have surpassed natural recharge capacity, becoming the fundamental cause of long-term groundwater depletion. This study underscores the urgency of promoting agricultural green transformation, optimizing crop planting structures, improving irrigation efficiency, and enhancing ecological conservation to rebuild groundwater resilience. Moreover, coordinated cross-border groundwater monitoring and management will be essential for ensuring the sustainable use of water resources in Northeast Asia’s transboundary river basins. Full article
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