Search Results (1,355)

Adaptive Linear Neuron (ADALINE) is a well-known neural network method that has been utilized for generating a reference current intended to regulate the operation of shunt-typed active harmonic filters (SAHFs). These filters are essential for improving power quality by mitigating harmonic disturbances and restoring current waveform symmetry in power systems. While the latest variant, Simplified ADALINE, offers notable advantages over its predecessors, such as a reduced complexity and faster learning speed, its performance has primarily been evaluated under stable grid conditions, leaving its performance under distorted environments largely unexplored. To address this gap, this work introduces two key modifications to the Simplified ADALINE framework: (1) the integration of a new phase-tracking algorithm based on the concept of orthogonality and selective filtering, and (2) transitioning from the direct current control (DCC) to an indirect current control (ICC) mechanism. Test environments featuring distorted grids and nonlinear rectifier loads are simulated in MATLAB/Simulink software to evaluate the performance of the proposed method against the existing Simplified ADALINE method. The key findings demonstrate that the proposed method effectively handled harmonic distortion and noise disturbance. As a result, the associated SAHF achieved an additional reduction in %THD (by 10.77–13.78%), a decrease in reactive power (by 58.3 VAR–67 VAR), and improved grid synchronization with a smaller phase shift (by 0.9–1.2°), while also maintaining proper waveform symmetry even in challenging grid conditions. Full article

Background: The aim of this study was to evaluate the diagnostic potential of salivary C-reactive protein (CRP) as a non-invasive biomarker for acute appendicitis in children and to compare its levels with those found in blood. Methods: Salivary and serum CRP levels were measured in patients with histologically confirmed acute appendicitis (n = 46) and a control group with non-specific abdominal pain (n = 43). Diagnostic performance was evaluated using receiver-operating characteristic analysis, while the agreement between salivary and serum CRP levels was evaluated using Spearman’s correlation and the Bland–Altman method. Results: Salivary CRP levels were significantly elevated in children with acute appendicitis than in controls (median 35.7 vs. 1.1 mg/L, p < 0.001), closely mirroring serum CRP trends (median 44.3 mg/L vs. 1.1 mg/L, p < 0.001). Moreover, they demonstrated excellent discriminatory power (Area Under the Curve; AUC = 0.97; 91.3% sensitivity, 95.4% specificity at the optimal cut-off of 6.95 mg/L), comparable to that of serum CRP (AUC = 0.98; 89.1% sensitivity and 95.4% specificity at 10.3 mg/L cut-off). Levels of CRP in serum and saliva were strongly correlated (Spearman’s ρ = 0.963, p < 0.001) and overall showed good agreement on Bland–Altman. Although larger discrepancies (>10 mg/L) occurred in 29% of cases, there was no consistent bias favoring either the salivary or serum CRP measurements. Conclusions: Salivary CRP is a promising non-invasive biomarker for diagnosing acute appendicitis in children, demonstrating diagnostic performance closely comparable to that of serum CRP and acceptable agreement between the two measures. This method may reduce the need for invasive blood sampling and streamline early evaluation in pediatric emergency settings. Full article

The accelerating threat of antimicrobial resistance (AMR) demands transformative strategies that go beyond conventional antibiotic therapies. Nanoparticles (NPs) have emerged as versatile antimicrobial agents, offering a combination of physical, chemical, and immunological mechanisms to combat multidrug-resistant (MDR) pathogens. Their small size, surface tunability, and ability to disrupt microbial membranes, generate reactive oxygen species (ROS), and deliver antibiotics directly to infection sites position them as powerful tools for infection control. This narrative review explores the major classes, mechanisms of action, and biomedical applications of antimicrobial NPs—including their roles in wound healing, implant coatings, targeted drug delivery, inhalation-based therapies, and the treatment of intracellular infections. We also highlight the current landscape of clinical trials and evolving regulatory frameworks that govern the translation of these technologies into clinical practice. A distinctive feature of this review is its focus on the interplay between NPs and the human microbiota—an emerging frontier with significant implications for therapeutic efficacy and safety. Addressing this bidirectional interaction is essential for developing microbiota-informed, safe-by-design nanomedicines. Despite promising advances, challenges such as scalability, regulatory standardization, and long-term biosafety remain. With interdisciplinary collaboration and continued innovation, antimicrobial NPs could reshape the future of infectious disease treatment and help curb the growing tide of AMR. Full article

The utilization of ammonia as a fuel for gas turbines involves practical challenges due to its low reactivity, narrow flammability limits, and slow laminar flame propagation. One of the potential solutions to enhance the combustion reactivity of ammonia is co-firing with syngas. This paper presents an experimental and numerical investigation of the laminar burning velocity (LBV) of ammonia/syngas/air mixtures under elevated pressures (up to 10 bar) and temperatures (up to 473 K). Experiments were conducted in a constant-volume combustion chamber with a total volume of 11 L equipped with a dual-electrode capacitive discharge ignition system. A systematic sensitivity analysis was conducted to experimentally evaluate the system performance under various syngas compositions and equivalence ratios from 0.7 to 1.6 and ultimately identify the factors with the most impact on the system. As a complement to the experiments, a detailed numerical simulation was carried out integrating available kinetic mechanisms—chemical reaction sets and their rates—to support advancements in the understanding and optimization of ammonia/syngas co-firing dynamics. The sensitivity analysis results reveal that LBV is significantly enhanced by increasing the hydrogen content (>50%). Furthermore, the LBV of the gas mixture is found to increase with the use of a rich flame, higher mole fractions of syngas, and higher initial temperatures. The results indicate that higher pressure reduces LBV by 40% but at the same time enhances the adiabatic flame temperature (by 100 K) due to an equilibrium shift. The analysis was also extended to quantify the impact of syngas mole fractions and elevated initial temperatures. The kinetics of the reactions are analyzed through the reaction pathways, and the results reveal how the preferred pathways vary under lean and rich flame conditions. These findings provide valid quantitative design data for optimizing the combustion kinetics of ammonia/syngas blends, offering valuable design data for ammonia-based combustion systems in industrial gas turbines and power generation applications, reducing NOₓ emissions by up to 30%, and guiding future research directions toward kinetic models and emission control strategies. Full article

To address the node voltage fluctuation and over-limit caused by the high penetration of distributed photovoltaic (PV) generation connected to distribution networks, this paper proposes a network partition-based optimal reactive power allocation and sizing method in the active distribution network (ADN). A network index incorporating network partition and critical node identification is introduced to obtain the optimal location for the reactive power compensation. A singular value entropy-based adaptive spectral clustering algorithm is applied to obtain the initial zones and obtain the critical nodes of each zone on the basis of the proposed network indexes. This method avoids the unreasonable scheme and enhances the efficiency and clarity of partitioning. The improved decimal coding method is proposed to improve the efficiency of the proposed method. A case study on the IEEE 33-node distribution system is carried out to verify the feasibility and effectiveness of the proposed method. The results show that compared with the conventional methods, the proposed method can effectively reduce voltage variations and control the voltage within the safe limit. Full article

The increasing penetration of renewable energy sources (RESs), such as photovoltaic and wind power plants, into the medium-voltage distribution grid creates significant concerns regarding voltage control at local substations. Understanding the specifics of the RES operation impact on the phenomenon and propagation of voltage fluctuations in the distribution grid is important for engineering solutions in the RES design and operation practice. The presented article describes an algorithm for estimating the impact of RES on voltage fluctuations in the medium-voltage grid. The algorithm utilises a RES fixed power factor control mode and is implemented in a grid model developed using software for power flow calculations. The study shows the impact of various RES power factor types on the nature of voltage fluctuations in the distribution grid. The RES operation with lagging reactive power factors, as a method of reducing voltage fluctuation magnitudes, results in a more complex nature of voltage fluctuation propagation compared to those with leading power factor. Based on simulations of a true medium-voltage grid, the possibility of optimal mitigation of voltage fluctuations in a grid by selecting the required RES reactive power factor has been proven. The presented model also allows for calculating changes in distribution grid energy losses depending on the RES reactive power factors, ensuring a practical solution of the control strategy. Full article

Magnetron Sputter Vacuum Deposition (MSVD) has undergone significant advancements since its inception. This review explores the evolution of MSVD, encompassing its fundamental principles, various techniques (including reactive sputtering, pulsed magnetron sputtering, and high-power impulse magnetron sputtering), and its wide-ranging industrial applications. While detailing the advantages of high deposition rates, versatility in material selection, and precise control over film properties, the review also addresses inherent challenges such as low target utilization and plasma instability. A significant portion focuses on the crucial role of MSVD in the automotive industry, highlighting its use in creating durable, high-quality coatings for both aesthetic and functional purposes. The transition from traditional electroplating methods to more environmentally friendly MSVD techniques is also discussed, emphasizing the growing demand for sustainable manufacturing processes. This review concludes by summarizing the key advancements, remaining challenges, and potential future trends in magnetron sputtering technologies. Full article

Background: This study aimed to examine the effects of an 8-week plyometric training program on lower-limb explosive strength, jump performance, musculotendinous stiffness, reactive strength index (RSI), and multidirectional speed in elite Polish badminton players. Methods: Twenty-four athletes were randomly assigned to either an experimental group (n = 15), which supplemented their regular badminton training with plyometric exercises, or a control group (n = 15), which continued standard technical training. Performance assessments included squat jump (SJ), countermovement jump (CMJ), single-leg jumps, sprint tests (5 m, 10 m), lateral movements, musculotendinous stiffness, and RSI measurements. Results: The experimental group showed statistically significant improvements in jump height, power output, stiffness, and 10 m sprint and lateral slide-step performance (p < 0.05), with large effect sizes. No significant changes were observed in the control group. Single-leg jump improvements suggested potential benefits for addressing lower-limb asymmetries. Conclusions: An 8-week plyometric intervention significantly enhanced lower-limb explosive performance and multidirectional movement capabilities in young badminton players. These findings support the integration of targeted plyometric training into regular training programs to optimize physical performance, improve movement efficiency, and potentially reduce injury risk in high-intensity racket sports. Full article

Achieving sustainable energy goals requires efficient integration of renewables like wind energy. Doubly fed induction generator (DFIG)-based wind turbine systems (WTSs) operate efficiently across a range of speeds, making them well-suited for modern renewable energy systems. However, sudden wind speed variations can cause power oscillations, rotor speed fluctuations, and voltage instability. Traditional proportional–integral (PI) controllers struggle with such nonlinear, rapidly changing scenarios. A control approach utilizing support vector regression (SVR) is proposed for the DFIG wind turbine system. The SVR controller manages both active and reactive power by simultaneously controlling the rotor- and grid-side converters (RSC and GSC). Simulations under a sudden wind speed variation from 10 to 12 m per second show the SVR approach reduces settling time significantly (up to 70.3%), suppresses oscillations in rotor speed, torque, and power output, and maintains over 97% DC-link voltage stability. These improvements enhance power quality, reliability, and system performance, demonstrating the SVR controller’s superiority over conventional PI methods for variable-speed wind energy systems. Full article

As the penetration rate of new energy continues to increase, the active voltage support capability of the power system is decreasing. The grid-forming static var generator (GFM-SVG) features the advantages of fast dynamic response, strong reactive power support, and high overload capacity, which play an important role in maintaining voltage stability. However, the parameters of the GFM-SVG are often unknown due to trade secret reasons. Meanwhile, the parameters may be changed during the long-term operation of the system, which brings challenges to the system stability analysis and control. Aiming at this problem, a parameter identification method based on trajectory sensitivity analysis and the proximal policy optimization (PPO) algorithm is proposed in this paper. Firstly, through trajectory sensitivity analysis, the key influential parameters on the output characteristics of the GFM-SVG can be selected, which can reduce the dimensionality of the identification parameters and improve the identification efficiency. Then, a parameter identification framework based on the PPO algorithm is constructed for GFM-SVGs, which utilizes its adaptive learning capability to achieve accurate identification of the key parameters of the system. Finally, the effectiveness of the proposed parameter identification method is verified through simulation examples. The simulation results show that the identification error of the parameters in the GFM-SVG is small. The proposed method can characterize the output response of the GFM-SVG under different operating conditions. Full article

This study examines the effect of oxygen concentration and sputtering power on the surface morphology of TiO₂ thin films deposited by DC reactive magnetron sputtering. Surface roughness parameters were obtained using MountainsMap^® software(10.2) from SEM images, while fractal dimensions and texture descriptors were extracted via Python-based image processing. Fractal dimension was calculated using the box-counting method applied to binarized images with multiple threshold levels, and texture analysis employed Gray-Level Co-occurrence Matrix (GLCM) statistics to capture local anisotropies and spatial heterogeneity. Four samples were analyzed, previously prepared with oxygen concentrations of 50% and 75%, and sputtering powers of 500 W and 1000 W. The results have shown that films deposited at higher oxygen levels and sputtering powers exhibited increased roughness, higher fractal dimensions, and stronger GLCM contrast, indicating more complex and heterogeneous surface structures. Conversely, films produced at lower oxygen and power settings showed smoother, more isotropic surfaces with lower complexity. This integrated analysis framework links deposition parameters with morphological characteristics, enhancing the understanding of surface evolution and enabling better control of TiO₂ thin film properties. Full article

Cervical cancer represents a significant global health challenge. Photodynamic therapy (PDT) appears to be a promising, minimally invasive alternative to standard treatments. However, the clinical efficacy of PDT is sometimes limited by the low solubility and aggregation of photosensitizers, their non-selective distribution in the body, hypoxia in the tumor microenvironment, and limited light penetration. Recent advances in nanoparticle and nanocomposite platforms have addressed these challenges by integrating multiple functional components into a single delivery system. By encapsulating or conjugating photosensitizers in biodegradable matrices, such as mesoporous silica, organometallic structures and core–shell construct nanocarriers increase stability in water and extend circulation time, enabling both passive and active targeting through ligand decoration. Up-conversion and dual-wavelength responsive cores facilitate deep light conversion in tissues, while simultaneous delivery of hypoxia-modulating agents alleviates oxygen deprivation to sustain reactive oxygen species generation. Controllable “motor-cargo” constructs and surface modifications improve intratumoral diffusion, while aggregation-induced emission dyes and plasmonic elements support real-time imaging and quantitative monitoring of therapeutic response. Together, these multifunctional nanosystems have demonstrated potent cytotoxicity in vitro and significant tumor suppression in vivo in mouse models of cervical cancer. Combining targeted delivery, controlled release, hypoxia mitigation, and image guidance, engineered nanoparticles provide a versatile and powerful platform to overcome the current limitations of PDT and pave the way toward more effective, patient-specific treatments for cervical malignancies. Our review of the literature summarizes studies on nanoparticles and nanocomposites used in PDT monotherapy for cervical cancer, published between 2023 and July 2025. Full article

For the high-voltage AC port of power electronic transformer (HVAC-PET) with three-phase independent DC buses on the low-voltage side, a decoupling control strategy, concerning the influence of grid voltage imbalance, three-phase active-load imbalance, and high-order harmonic distortion, is proposed in this paper to simultaneously realize the functions of active power control, reactive power compensation, and active power filtering. In the outer power control loop, according to the distribution rule of decoupled average active power components in three phases, stability control for the sum of cluster average active power flows is realized by injecting positive-sequence active current, so as to control the average cluster voltage (i.e., the average of all the DC-link capacitor voltages), and by injecting negative-sequence current, the cluster average active power flows can be controlled individually to balance the three cluster voltages (i.e., the average of the DC-link capacitor voltages in each cluster). The negative-sequence reactive power component is considered to realize the reactive power compensation. In the inner current control loop, the fundamental and high-order harmonic components are uniformly controlled in the positive-sequence dq frame using the PI + VPIs (vector proportional integral) controller, and the harmonic filtering function is realized while the fundamental positive-sequence current is adjusted. Experiments performed on the 380 V/50 kVA laboratory HVAC-PET verify the effectiveness of the proposed control strategy. Full article

This study aimed to investigate the efficacy of a composite coating composed of 150 mg/L ε-Poly-L-lysine (ε-PL) and 5 g/L chitosan (CTS) in extending the shelf life and maintaining the postharvest quality of fresh Tremella fuciformis. Freshly harvested T. fuciformis were treated by surface spraying, with distilled water serving as the control. The effects of the coating on storage quality, physicochemical properties, reactive oxygen species (ROS) metabolism, and membrane lipid metabolism were evaluated during storage at (25 ± 1) °C. The results showed that the ε-PL/CTS composite coating significantly retarded quality deterioration, as evidenced by reduced weight loss, maintained whiteness and color, and higher retention of soluble sugars, soluble solids, and soluble proteins. The coating also effectively limited water migration and loss. Mechanistically, the coated T. fuciformis exhibited enhanced antioxidant capacity, characterized by increased superoxide anion (O₂⁻) resistance capacity, higher activities of antioxidant enzymes (SOD, CAT, APX), and elevated levels of non-enzymatic antioxidants (AsA, GSH). This led to a significant reduction in malondialdehyde (MDA) accumulation, alongside improved DPPH radical scavenging activity and reducing power. Furthermore, the ε-PL/CTS coating preserved cell membrane integrity by inhibiting the activities of lipid-degrading enzymes (lipase, LOX, PLD), maintaining higher levels of key phospholipids (phosphatidylinositol and phosphatidylcholine), delaying phosphatidic acid accumulation, and consequently reducing cell membrane permeability. In conclusion, the ε-PL/CTS composite coating effectively extends the shelf life and maintains the quality of postharvest T. fuciformis by modulating ROS metabolism and preserving membrane lipid homeostasis. This study provides a theoretical basis and a practical approach for the quality control of fresh T. fuciformis. Full article

With the rapid development of renewable energy, the proportion of small hydropower as a clean energy in the distribution network (DN) is increasing. However, the randomness and intermittence of small hydropower has brought new challenges to the operation of DN; especially, the problems of increasing network loss and reactive voltage exceeding the limit have become increasingly prominent. Aiming at the above problems, this paper proposes a reactive power optimization control method for DN with hydropower based on an improved discrete particle swarm optimization (PSO) algorithm. Firstly, this paper analyzes the specific characteristics of small hydropower and establishes its mathematical model. Secondly, considering the constraints of bus voltage and generator RP output, an extended minimum objective function for system power loss is established, with bus voltage violation serving as the penalty function. Then, in order to solve the following problems: that the traditional discrete PSO algorithm is easy to fall into local optimization and slow convergence, this paper proposes an improved discrete PSO algorithm, which improves the global search ability and convergence speed by introducing adaptive inertia weight. Finally, based on the IEEE-33 buses distribution system as an example, the simulation analysis shows that compared with GA optimization, the line loss can be reduced by 3.4% in the wet season and 13.6% in the dry season. Therefore, the proposed method can effectively reduce the network loss and improve the voltage quality, which verifies the effectiveness and superiority of the proposed method. Full article