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Keywords = rapid calibration method

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23 pages, 43629 KB  
Article
An Improved Framework for Forest Fire Severity Assessment in Mountainous Areas Based on the dNBR Index: A Case Study from Central Yunnan, China
by Li Han, Yun Liu, Qiuhua Wang, Tengteng Long, Ning Lu, Leiguang Wang and Weiheng Xu
Remote Sens. 2026, 18(8), 1118; https://doi.org/10.3390/rs18081118 - 9 Apr 2026
Abstract
Forest fires pose a considerable threat to the security of ecosystems and human society, rendering accurate assessments of fire severity critical for ecological recovery and effective fire management. The differenced Normalized Burn Ratio (dNBR) has been employed to evaluate forest fire severity; however, [...] Read more.
Forest fires pose a considerable threat to the security of ecosystems and human society, rendering accurate assessments of fire severity critical for ecological recovery and effective fire management. The differenced Normalized Burn Ratio (dNBR) has been employed to evaluate forest fire severity; however, it presents notable uncertainties owing to variations in data sources, temporal phases, and environmental factors. To address these challenges, this study analyzed 10 forest fires occurring between 2006 and 2023 in central Yunnan Province, China. First, a rapid sampling method utilizing very high-resolution imagery was developed to assess the performance of dNBR classification under varying conditions. Second, the study identified the optimal post-fire observation window and compared classification thresholds and accuracy between Landsat and Sentinel-2 imagery in assessing fire severity. Finally, the research explored the impacts of topographic correction and pre-fire vegetation differences on classification outcomes. The findings revealed the following: (1) Imagery captured in the spring of the fire year, characterized by minimal vegetation interference, demonstrated the highest classification stability and superior capability for identifying high-severity burns. (2) Landsat outperformed Sentinel-2 in regional accuracy (0.92 vs. 0.87), and direct threshold transfer between sensors resulted in a 39% underestimation of high-severity areas, underscoring the necessity for sensor-specific calibration. (3) Topographic correction provided limited practical benefits, merely yielding a marginal improvement in accuracy (+1.44%) with the SCS+C model in steep terrain, and was generally unnecessary. (4) The influence of pre-fire vegetation was discovered to be threshold-dependent: dNBR performed reliably in forests with pre-fire NDVI > 0.5, while adjusted approaches were solely recommended for sparse or heterogeneous vegetation. Overall, this study establishes a systematic framework for optimizing dNBR-based severity assessment, enhancing its accuracy and operational utility in forest fire management. Full article
(This article belongs to the Special Issue Forest Fire Monitoring Using Remotely Sensed Imagery)
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18 pages, 2170 KB  
Article
Mold Detection in Sweet Tamarind During Storage Performed by Near-Infrared Spectroscopy and Chemometrics
by Muhammad Zeeshan Ali, Pimjai Seehanam, Darunee Naksavi and Phonkrit Maniwara
Horticulturae 2026, 12(4), 462; https://doi.org/10.3390/horticulturae12040462 - 8 Apr 2026
Viewed by 170
Abstract
Mold infection by Aspergillus and Penicillium spp. in Sithong sweet tamarind (Tamarindus indica L.) during commercial postharvest storage poses quality and food safety risks. However, the current visual detection method, which involves randomly cracking open the pods, is both destructive and laborious. [...] Read more.
Mold infection by Aspergillus and Penicillium spp. in Sithong sweet tamarind (Tamarindus indica L.) during commercial postharvest storage poses quality and food safety risks. However, the current visual detection method, which involves randomly cracking open the pods, is both destructive and laborious. The integration of near-infrared spectroscopy (NIRS) with artificial neural networks (ANN) enables rapid and non-destructive detection while capturing non-linear biochemical–spectral relationships, offering advantages over conventional destructive and linear analytical methods. It was tested as a mold classifier in sweet tamarind pods preserved in commercial ambient conditions (25 °C, 60% relative humidity) for five weeks. Six hundred pods were examined weekly using interactance spectroscopy (800–2500 nm) with six measurement points per pod and four spectral preprocessing methods. The ANN outperformed partial least squares discriminant analysis (PLS-DA) across all storage weeks, peaking at Week 2 with standard normal variate (SNV) preprocessing (prediction accuracy: 85.00%; sensitivity: 0.84; specificity: 0.86; F1-score: 0.85). Advanced tissue degeneration caused spectral heterogeneity, which decreased performance at Week 4 (prediction accuracy: 71.82–76.36%). Principal component loadings identified mold-induced water redistribution and carbohydrate depletion wavelengths at 938, 975–980, and 1035 nm. Week-adaptive calibration is essential for implementation because of the large difference between week-specific model accuracy (up to 85%) and overall storage model accuracy (63.53%). These findings provide a mechanistic underpinning for smaller wavelength-selective sensors and temporally adaptive mold screening systems in commercial tamarind storage. Full article
(This article belongs to the Section Postharvest Biology, Quality, Safety, and Technology)
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13 pages, 2280 KB  
Article
Quantitative Assessment of SBS-Modifier Content in Bituminous Binders Using Infrared Spectroscopy
by Saltanat Ashimova, Yerik Amirbayev, Adiya Zhumagulova, Manarbek Zhumamuratov, Sakypzhamal Begaliyeva, Zhanar Baibolekova and Mariya Smagulova
Polymers 2026, 18(8), 898; https://doi.org/10.3390/polym18080898 - 8 Apr 2026
Viewed by 176
Abstract
Polymer-modified bituminous binders are widely used in road construction due to their enhanced mechanical performance; however, the effectiveness of these materials critically depends on the actual concentration of polymer modifiers, particularly styrene-butadiene-styrene (SBS). This study aims to develop and validate a rapid, reproducible [...] Read more.
Polymer-modified bituminous binders are widely used in road construction due to their enhanced mechanical performance; however, the effectiveness of these materials critically depends on the actual concentration of polymer modifiers, particularly styrene-butadiene-styrene (SBS). This study aims to develop and validate a rapid, reproducible Fourier Transform Infrared Spectroscopy—Attenuated Total Reflectance (FTIR-ATR) spectroscopy method for the quantitative determination of SBS content in polymer-modified bitumen (PMB). Since, to date, there is no clearly defined method for controlling the quantitative content of polymers in PMB, this creates difficulties in accepting the roadway into operation. Calibration PMB samples containing 1–4% SBS were prepared, tested for physical and mechanical properties, and analyzed spectroscopically to identify characteristic absorption bands at 966 cm−1 and 699–760 cm−1. A first-order calibration model was constructed to relate peak intensity to polymer concentration. The results demonstrate a clear linear correlation between SBS content and IR absorption features, confirming the suitability of FTIR as an instrumental method for routine laboratory control. Application of the model allowed determination of actual polymer mass fraction with high accuracy and reproducibility. The findings also showed that increased SBS levels improve softening point, elasticity, and low-temperature resistance, with 3–4% representing a performance-optimal range. Overall, the proposed FTIR-based approach provides an objective and efficient tool for quality control of polymer-modified binders and supports broader standardization efforts in the field. Full article
(This article belongs to the Section Polymer Applications)
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65 pages, 8778 KB  
Systematic Review
Beyond Accuracy: Transferability Limits, Validation Inflation, and Uncertainty Gaps in Satellite-Based Water Quality Monitoring—A Systematic Quantitative Synthesis and Operational Framework
by Saeid Pourmorad, Valerie Graw, Andreas Rienow and Luca Antonio Dimuccio
Remote Sens. 2026, 18(7), 1098; https://doi.org/10.3390/rs18071098 - 7 Apr 2026
Viewed by 221
Abstract
Satellite remote sensing has become essential for water quality assessment across inland and coastal environments, with rapid improvements in recent years. Significant advances have been made in detecting optically active parameters (such as chlorophyll-a, suspended matter, and turbidity), showing consistently strong performance across [...] Read more.
Satellite remote sensing has become essential for water quality assessment across inland and coastal environments, with rapid improvements in recent years. Significant advances have been made in detecting optically active parameters (such as chlorophyll-a, suspended matter, and turbidity), showing consistently strong performance across multiple studies. Specifically, the median validation performance (R2) derived from the quantitative synthesis indicates R2 = 0.82 for chlorophyll-a (interquartile range—IQR: 0.75–0.90), R2 = 0.80 for total suspended matter (IQR: 0.78–0.85), and R2 = 0.88 for turbidity (IQR: 0.85–0.90). Conversely, the retrieval of optically inactive parameters (such as nutrients like total phosphorus and total nitrogen) remains more context dependent. It exhibits moderate, more variable results, with median R2 = 0.68 (IQR: 0.64–0.74) for total phosphorus and R2 = 0.75 (IQR: 0.70–0.80) for total nitrogen. These findings clearly illustrate the varying success of retrievals of optically active and inactive parameters and underscore the inherent difficulties of indirect estimation methods. However, high reported accuracy has yet to translate into transferable, uncertainty-informed, and operational monitoring systems. This gap stems from structural issues in validation design, physics integration, uncertainty management, and multi-sensor compatibility rather than data limitations alone. We present a PRISMA-guided, distribution-aware quantitative synthesis of 152 peer-reviewed studies (1980–2025), based on a systematic search protocol, to evaluate satellite-based retrievals of both optically active and inactive parameters. Instead of simply averaging performance, we analyse the empirical distributions of validation metrics, considering the validation protocol, sensor type, parameter category, degree of physics integration, and uncertainty quantification. The synthesis demonstrates that validation strategy often influences reported results more than the algorithm class itself, with accuracy inflated under non-independent cross-validation methods and notable variability between studies concealed by mean-based reports. Across four decades, four persistent structural challenges remain: limited transferability across sites and sensors beyond calibration areas; weak or implicit physical integration in many data-driven models; lack of or inconsistency in uncertainty quantification; and fragmented multi-sensor harmonisation that restricts operational scalability. To address these issues, we introduce two evidence-based coding frameworks: a physics-integration taxonomy (P0–P4) and an uncertainty-quantification hierarchy (U0–U4). Applying these frameworks shows that most studies remain focused on low-to-moderate levels of physics integration and primarily consider uncertainty at the prediction stage, with limited attention to upstream sources throughout the observation and inference process. Building on this structured synthesis, we propose a transferable, physics-informed, and uncertainty-aware conceptual framework that links model architecture, validation robustness, and probabilistic uncertainty to well-founded design principles. By shifting satellite water quality modelling from isolated algorithm demonstrations towards integrated, evidence-based system design, this study promotes scalable, decision-grade environmental monitoring amid the accelerating impacts of climate change. Full article
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33 pages, 2336 KB  
Article
Machine Learning-Assisted FTIR Spectroscopy Analysis of Kidney Preservation Fluids for Delayed Graft Function Risk Stratification
by Luis Ramalhete, Rúben Araújo, Miguel Bigotte Vieira, Emanuel Vigia, Ana Pena, Sofia Carrelha, Cristiana Teixeira, Anibal Ferreira and Cecilia R. C. Calado
J. Clin. Med. 2026, 15(7), 2762; https://doi.org/10.3390/jcm15072762 - 6 Apr 2026
Viewed by 269
Abstract
Background/Objectives: Delayed graft function (DGF) remains a common early complication after deceased donor kidney transplantation and is challenging to anticipate using routine pre-implant clinical variables alone. We investigated whether high-throughput Fourier transform infrared (FTIR) spectroscopy of static cold storage preservation fluid (not [...] Read more.
Background/Objectives: Delayed graft function (DGF) remains a common early complication after deceased donor kidney transplantation and is challenging to anticipate using routine pre-implant clinical variables alone. We investigated whether high-throughput Fourier transform infrared (FTIR) spectroscopy of static cold storage preservation fluid (not machine perfusion perfusate) captures biochemical information associated with DGF and warrants further evaluation alongside routine pre-implant clinical predictors. Methods: In this single-center retrospective cohort, we analyzed preservation fluid samples from 56 kidney transplants originating from 49 deceased donors (7 donors contributed two kidneys); DGF occurred in 14/56 (25.0%). Dried-film FTIR spectra were acquired using a plate-based high-throughput accessory, and analyses focused on the fingerprint region (900–1800 cm−1) with prespecified preprocessing and quality control. We developed and compared clinical-only, FTIR-only, and combined predictive models and estimated performance using donor-blinded 5-fold StratifiedGroupKFold cross-validation (grouped by donor code) to prevent leakage across paired kidneys. Results: Donor-blinded discrimination (pooled out-of-fold ROC-AUC) was 0.775 for the clinical-only model, 0.814 for the FTIR-only model, and 0.796 for the combined model; probabilistic accuracy (Brier score; lower is better) was 0.162, 0.194, and 0.177, respectively. Calibration intercepts were negative and slopes were <1, indicating overly extreme risk estimates under strict donor-blinded validation and supporting recalibration prior to deployment. Decision curve analysis suggested a positive net benefit for clinically plausible thresholds. Conclusions: These findings support the feasibility of rapid, low-cost FTIR profiling of routinely available preservation fluid as a proof-of-concept approach for exploratory DGF risk stratification, rather than as a clinically deployable prediction tool. Given the small sample size and the instability of subgroup estimates, the main next steps are external validation in larger multicenter cohorts, prospective workflow studies, and model updating/recalibration. Full article
(This article belongs to the Section Nephrology & Urology)
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30 pages, 4983 KB  
Article
A Predictive Model for Separation Efficiency in Gas–Liquid Cyclone Separators
by Dongjing Chen, Jin Zhang, Ruiqi Lv, Ying Li and Xiangdong Kong
Processes 2026, 14(7), 1157; https://doi.org/10.3390/pr14071157 - 3 Apr 2026
Viewed by 252
Abstract
Entrained gas in hydraulic oil undermines system stability. A rapid engineering method for predicting the separation efficiency of gas–liquid cyclone separators is still lacking. This study proposes an engineering-oriented predictive framework by combining the split ratio, the characteristic scale of the locus of [...] Read more.
Entrained gas in hydraulic oil undermines system stability. A rapid engineering method for predicting the separation efficiency of gas–liquid cyclone separators is still lacking. This study proposes an engineering-oriented predictive framework by combining the split ratio, the characteristic scale of the locus of zero vertical velocity envelope, and the axial residence time. A relative migration index, derived from maximum tangential velocity and axial residence time, is coupled with a relative overflow-pipe insertion indicator to characterize the interaction between swirl intensity and effective separation space. The separation-capability transition is described using a coupled logistic mapping. Model coefficients are identified via Eulerian–Eulerian simulations on a calibration set. The model was evaluated on isolated simulation validation sets with varying geometries and inlet gas volume fractions, yielding an R2 of 0.762 and a root mean square error (RMSE) of 0.07. Particle Image Velocimetry validation tests on one representative prototype geometry gave RMSE values of 0.061 for simulation versus test and 0.108 for prediction versus test. The framework captures the macroscopic trend of separation efficiency within the investigated range, with the caveat that part of the model coefficients and intermediate inputs remain conditioned by simulation-derived quantities. Full article
(This article belongs to the Section Separation Processes)
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23 pages, 1017 KB  
Article
Interval-Based Tropical Cyclone Intensity Forecasting with Spatiotemporal Transformers
by Tao Guo, Hua Zhang, Tao Song and Shiqiu Peng
Remote Sens. 2026, 18(7), 1069; https://doi.org/10.3390/rs18071069 - 2 Apr 2026
Viewed by 248
Abstract
Accurate tropical cyclone (TC) intensity forecasting remains challenging due to the strong nonlinearity of intensity evolution and the rapid structural changes associated with storm development. In this work, we propose TC-QFormer, an interval-based probabilistic framework for 24 h TC intensity forecasting that combines [...] Read more.
Accurate tropical cyclone (TC) intensity forecasting remains challenging due to the strong nonlinearity of intensity evolution and the rapid structural changes associated with storm development. In this work, we propose TC-QFormer, an interval-based probabilistic framework for 24 h TC intensity forecasting that combines transformer-based spatiotemporal modeling with scalar conditioning. Specifically, we adapt the PredFormer video prediction model for multi-horizon scalar regression and introduce a lightweight Scalar–Image Fusion Block to incorporate historical intensity information into the visual representations. A two-stage training strategy is adopted, in which the model is first pretrained for deterministic median prediction and subsequently fine-tuned to directly predict multiple conditional quantiles using the pinball loss. Experiments are conducted on the TCIR dataset using geostationary infrared and water vapor satellite imagery together with aligned historical intensity records. The proposed method is evaluated against representative recurrent and non-recurrent baselines, including ConvLSTM, PredRNN, and SimVP. Results indicate that the proposed framework achieves improved deterministic accuracy and produces well-calibrated 80% prediction intervals, particularly at longer forecast lead times and during rapidly evolving intensity regimes. These findings suggest that combining transformer-based spatiotemporal modeling with scalar–image conditioning provides an effective and interpretable approach for probabilistic TC intensity forecasting. Full article
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32 pages, 9172 KB  
Article
Design, Modeling, Self-Calibration and Grasping Method for Modular Cable-Driven Parallel Robots
by Wanlin Mai, Yonghe Wang, Zhiquan Yang, Bin Zhu, Lin Liu and Jianqing Peng
Sensors 2026, 26(7), 2204; https://doi.org/10.3390/s26072204 - 2 Apr 2026
Viewed by 237
Abstract
Cable-driven parallel robots (CDPRs) are attractive for large-space manipulation because of their lightweight structure, large workspace, and reconfigurability. However, existing systems still face three practical challenges: limited modularity of the mechanical architecture, repeated calibration after reconfiguration, and insufficient integration between visual perception and [...] Read more.
Cable-driven parallel robots (CDPRs) are attractive for large-space manipulation because of their lightweight structure, large workspace, and reconfigurability. However, existing systems still face three practical challenges: limited modularity of the mechanical architecture, repeated calibration after reconfiguration, and insufficient integration between visual perception and grasp execution. To address these issues, this paper presents a modular cable-driven parallel robot (MCDPR), together with its kinematic modeling, vision-based self-calibration, and visual grasping methods. First, a modular mechanical architecture is developed in which the drive, sensing, and cable-guiding functions are integrated to support rapid assembly/disassembly, convenient debugging, and cable anti-slack operation. Second, a pulley-considered multilayer kinematic model is established, and a vision-based self-calibration method is proposed to identify the structural parameters after assembly using onboard sensing and AprilTag observations, thereby reducing the number of recalibrations required during robot operation after reconfiguration. Third, a vision-guided bin-picking method is developed by combining RGB-D perception, coordinate transformation, and the calibrated robot model. Simulation and prototype experiments are conducted to validate the proposed system. A software/hardware combined validation framework is established, in which the CoppeliaSim-based simulation and the hardware prototype are used together to verify the proposed design and methods. In simulation, self-calibration reduces the Euclidean grasping position error from 0.371 mm to 0.048 mm and the orientation error from 0.071° to 0.004°. In experiments, the relative position error is reduced by 58.33% after self-calibration. Full article
(This article belongs to the Special Issue Motor Control and Remote Handling in Robotic Applications)
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21 pages, 2146 KB  
Article
Resolution of Creatinine Interference in Dexamethasone Sodium Phosphate Injectable Preparations: A Validated First-Order Derivative Spectrophotometric Method Using Matrix Matching and Zero-Crossing Point Interpolation
by Daniela-Mădălina Anghel, Anne-Marie Ciobanu, Daniela-Luiza Baconi, Mircea Bogdan Măciuceanu Zărnescu and George Traian Alexandru Burcea-Dragomiroiu
AppliedChem 2026, 6(2), 23; https://doi.org/10.3390/appliedchem6020023 - 2 Apr 2026
Viewed by 182
Abstract
Background: The quantification of Dexamethasone Sodium Phosphate (DSP) in injectable formulations is significantly hindered by the spectral overlap of the stabilizer creatinine within the UV region. This study aims to develop a green first-order derivative (D1) spectrophotometric method to resolve this [...] Read more.
Background: The quantification of Dexamethasone Sodium Phosphate (DSP) in injectable formulations is significantly hindered by the spectral overlap of the stabilizer creatinine within the UV region. This study aims to develop a green first-order derivative (D1) spectrophotometric method to resolve this analytical challenge. Methods: Distilled water was utilized as a sustainable solvent, aligning with green chemistry principles. To ensure high specificity, a matrix-matching calibration strategy with a constant 1:2 (w/w) DSP:creatinine mass ratio across the entire concentration range was employed. DSP was determined using the zero-crossing technique, measuring the D1 amplitude at λZC ≅ 231.3 nm, where the creatinine contribution is nullified. Results: Linearity was established for DSP concentrations between 4.0–16.0 μg/mL (R2 > 0.99). Method validation, as per ICH Q2 (R1) guidelines (International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use), demonstrated excellent accuracy (mean recovery of 99.85%) and precision (RSD < 2%). Conclusions: The proposed method offers a rapid, cost-effective, and eco-friendly alternative for the routine quality control of DSP injectables, eliminating the necessity for complex chromatographic separation techniques. Full article
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23 pages, 5349 KB  
Article
Target Tracking-Based Online Calibration of UAV Electro-Optical Pod Installation Errors
by Yong Xu, Jin Liu, Hongtao Yan, An Wang, Haihang Xu, Yue Ma and Tian Yao
Automation 2026, 7(2), 59; https://doi.org/10.3390/automation7020059 - 1 Apr 2026
Viewed by 362
Abstract
As the “visual perception hub” of unmanned aerial vehicles (UAVs), electro-optical (EO) pods play an increasingly critical role in tasks such as intelligence gathering, situational awareness, target tracking, and localization. With the expanding scope and depth of UAV applications, higher demands are placed [...] Read more.
As the “visual perception hub” of unmanned aerial vehicles (UAVs), electro-optical (EO) pods play an increasingly critical role in tasks such as intelligence gathering, situational awareness, target tracking, and localization. With the expanding scope and depth of UAV applications, higher demands are placed on the precision and adaptability of installation error calibration techniques for EO pods. Current mainstream calibration methods typically require specialized procedures under constrained conditions, while few approaches integrate existing UAV system capabilities and mission requirements, which leads to cumbersome, time-consuming processes and suboptimal alignment between calibration outcomes and task objectives. This paper proposes an online calibration method for UAV EO pod installation errors based on target tracking, which can rapidly compute the optimal closed-form solution for installation errors by leveraging UAV tracking missions. First, an observation equation for pod installation errors is established using tracking results. Second, multi-temporal observations are combined to model the calibration problem as an optimal rotation matrix estimation task, and then the optimal closed-form solution for installation errors is derived. Concurrently, a statistics-based approximate calibration method is introduced specifically for tracking missions. Furthermore, an online calibration system compatible with diverse UAV platforms is designed, along with different rapid calibration schemes for emergency response scenarios, fully incorporating existing system capabilities and mission needs. Finally, a fixed-wing UAV experimental platform is developed, with calibration tests conducted under various flight regimes. Experimental results validate the feasibility and robustness of the proposed methodology. Full article
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26 pages, 8202 KB  
Article
An Integrated Multi-Criteria and Hydrological Consistency Framework for Evaluating Latest Satellite-Based Winter Precipitation Products in Himalayan Basins
by Mohammad Tayib Bromand, Mohamed Rasmy, Katsunori Tamakawa, Subash Tuladhar and Toshio Koike
Remote Sens. 2026, 18(7), 1051; https://doi.org/10.3390/rs18071051 - 31 Mar 2026
Viewed by 304
Abstract
Winter precipitation plays an important role in the Himalayan region. However, its reliable assessment is difficult due to sparse ground precipitation measurements, limited ability to capture heterogeneity, and snowfall undercatch. Recent advances in satellite-based winter precipitation products (SPPs) enable comprehensive, consistent spatial data [...] Read more.
Winter precipitation plays an important role in the Himalayan region. However, its reliable assessment is difficult due to sparse ground precipitation measurements, limited ability to capture heterogeneity, and snowfall undercatch. Recent advances in satellite-based winter precipitation products (SPPs) enable comprehensive, consistent spatial data in this region; however, despite rapid improvements and the increased availability of SPPs, their accuracy is still uncertain. This calls for rigorous evaluation across several regions. This study presents a new SPP evaluation method that extends existing frameworks by adding two additional indicators—spatial correlation and the water balance consistency ratio (WBCR) to create a unified multi-criteria matrix for selecting spatially and hydrologically consistent products from among 11 latest and earlier SPPs from the global satellite mapping of precipitation (GSMaP) and The integrated multi-satellite retrievals for the global precipitation measurement Mission (IMERG) in the Kabul, Dudhkoshi, and Chamkharchu River basins. The results show that the latest non-calibrated product performed significantly better than earlier releases, demonstrating improved ability to capture precipitation events, spatial heterogeneity, and WBCR across all three basins. However, the performance of those SPPs varies substantially across regions. GSMaP gauge-calibrated product performance was more consistent across conventional multi-criteria assessment and WBCR, but their inability to capture spatial heterogeneity limits their applicability for sub-catchment water resource management. On the other hand, IMERG Final V07 (gauge-calibrated) performed exceptionally well across all regions, although its 3.5 month latency limits near-real-time applications. Therefore, GSMaP NRT V08 is suitable for real-time applications, given its short ~4 h latency and relatively good performance across all three basins. Future studies using the selected products will provide reliable information for policymakers and will support water hazard risk reduction. Full article
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21 pages, 978 KB  
Review
Artificial Intelligence for Computer-Aided Detection in Endovascular Interventions: Clinical Applications, Validation, and Translational Perspectives
by Rasit Dinc and Nurittin Ardic
Bioengineering 2026, 13(4), 399; https://doi.org/10.3390/bioengineering13040399 - 29 Mar 2026
Viewed by 474
Abstract
Background: Artificial intelligence-based computer-aided detection (AI-CAD) systems are increasingly being used in endovascular practice to support time-sensitive detection, triage and prioritization tasks in imaging and procedural workflows. Despite rapid technological advancements and expanding regulatory clearances, the translation to lasting clinical benefit varies. Objective: [...] Read more.
Background: Artificial intelligence-based computer-aided detection (AI-CAD) systems are increasingly being used in endovascular practice to support time-sensitive detection, triage and prioritization tasks in imaging and procedural workflows. Despite rapid technological advancements and expanding regulatory clearances, the translation to lasting clinical benefit varies. Objective: This narrative review synthesizes AI-CAD applications in endovascular interventions and proposes an evaluation-oriented framework to support responsible clinical translation; this framework emphasizes detection-specific metrics, external validation, bias-aware assessment, and workflow integration. Methods: A structured narrative review was conducted using targeted searches in PubMed, Google Scholar, and IEEE Xplore (2020–2026); this review was supported by an examination of US FDA device databases and citation tracking. Evidence was assessed using a pragmatic hierarchical classification framework based on regulatory status and validation rigor. Results: AI-CAD applications were mapped across four main endovascular domains: neurovascular interventions (e.g., large vessel occlusion triage), coronary interventions (CCTA-based stenosis detection and intravascular imaging support), aortic interventions/EVAR (endoleak detection and sac monitoring), and peripheral interventions (lesion detection and angiographic decision support). Across the domains, performance reporting was heterogeneous and often relied on retrospective, single-center assessments. Key barriers to clinical readiness included acquisition variability and dataset shift due to artifacts, limited multicenter validation, annotation variability, and human–AI workflow factors. Evaluation priorities included whether to assess at the lesion level or case level, false positive burden and calibration, external validation under real-world heterogeneity, and clinical impact measures such as treatment timing and procedural decision-making. Conclusions: AI-CAD systems hold significant potential for improving endovascular care; however, clinical readiness depends on rigorous, endovascular feature-specific assessment and transparent reporting, beyond retrospective accuracy. The proposed evidence level framework and assessment checklist provide practical tools for distinguishing mature technologies from research prototypes and guiding future validation, implementation, and post-market monitoring. Full article
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32 pages, 6451 KB  
Article
A Fast Synaptic Parameter Estimation Method Based on First- and Second-Order Moments for Short-Term Facilitating Synapses
by Jingyi Zhang, Tianyu Li, Xiaohui Zhang and Liber T. Hua
Biomedicines 2026, 14(4), 771; https://doi.org/10.3390/biomedicines14040771 - 28 Mar 2026
Viewed by 274
Abstract
Background: Short-term facilitation (STF) is a key form of synaptic plasticity driven by activity-dependent increases in presynaptic release probability. However, estimating core synaptic parameters—quantal size (q), vesicle pool size (N), and release probability (pi)—remains challenging [...] Read more.
Background: Short-term facilitation (STF) is a key form of synaptic plasticity driven by activity-dependent increases in presynaptic release probability. However, estimating core synaptic parameters—quantal size (q), vesicle pool size (N), and release probability (pi)—remains challenging due to nonlinear dynamics and unobservable presynaptic states, limiting the applicability of conventional methods. Methods: We developed a fast analytical framework based on first- and second-order statistical moments of evoked EPSCs, including mean, variance, and cross-stimulus covariance. By constructing composite moment relationships, latent variables were algebraically eliminated, yielding closed-form estimators of synaptic parameters. To improve robustness under strong facilitation, a Tsodyks–Markram (T–M) model-based calibration step was introduced to refine N and pi using the estimated q as a constraint. Results: Applied to hippocampal CA3–CA1 synapses, the method produced accurate and stable estimates of q across varying noise and sampling conditions. Incorporation of cross-stimulus covariance enabled effective characterization of structured variability that is neglected in classical approaches. While direct estimates of N and pi showed dispersion, T–M calibration significantly improved stability and physiological consistency. Compared with mean–variance analysis, the proposed method achieved superior performance under facilitating conditions. Conclusions: This hybrid framework enables rapid and reliable estimation of synaptic parameters in STF synapses by exploiting second-order statistical structure. It provides a practical tool for investigating presynaptic mechanisms and may facilitate quantitative studies of synaptic dysfunction in neurological and psychiatric disorders. Full article
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27 pages, 12956 KB  
Article
Research on Magnetorheological Semi-Active Suspension Control Using RBF Neural Network-Tuned Active Disturbance Rejection Control
by Mei Li, Shuaihang Liu, Shaobo Zhang and Xiaoxi Hu
Actuators 2026, 15(4), 184; https://doi.org/10.3390/act15040184 - 27 Mar 2026
Viewed by 301
Abstract
Magnetorheological (MR) semi-active suspensions offer clear advantages in improving ride comfort and handling stability, yet their engineering applications are often hindered by strong nonlinear hysteresis of the damper, the randomness of road excitations, and the reliance on manual tuning of controller parameters. To [...] Read more.
Magnetorheological (MR) semi-active suspensions offer clear advantages in improving ride comfort and handling stability, yet their engineering applications are often hindered by strong nonlinear hysteresis of the damper, the randomness of road excitations, and the reliance on manual tuning of controller parameters. To address these issues, this paper proposes an integrated framework of “experimental modeling–semi-active implementation–adaptive control.” First, characteristic tests of the MR damper are conducted, based on which a current-dependent Bouc–Wen forward model is established. Tianji’s Horse Racing Optimization (THRO) is then employed for parameter identification to reproduce the hysteresis behavior accurately. Second, a back propagation (BP) neural network-based inverse current model is developed to achieve rapid mapping from “desired damping force” to “driving current,” enabling semi-active actuation. Furthermore, a radial basis function (RBF) neural network is embedded into the active disturbance rejection control (ADRC) structure to estimate the system Jacobian online and to tune key extended state observer (ESO) gains in real time, forming the proposed RBF-ADRC strategy and thereby enhancing disturbance observation and compensation capability. Simulation results under pulse-road and Class-C random-road excitations show that, compared with the passive suspension, the proposed method reduces the root mean square error values of sprung-mass acceleration, suspension dynamic deflection, and tire dynamic load by 25.14%, 18.71%, and 11.61%, respectively, while also outperforming skyhook control and fixed-gain ADRC. Frequency-domain results further show stronger attenuation in the low-frequency band relevant to body vibration. Under pulse excitation, RBF-ADRC yields smaller peak and trough body accelerations and faster post-impact recovery. Under ±30% sprung-mass variations, it achieves the best worst-case and fluctuation-range robustness among the compared strategies and remains close to offline retuning. These results demonstrate that the proposed method improves both control performance and robustness while reducing the need for repeated manual calibration. Full article
(This article belongs to the Section Actuators for Surface Vehicles)
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Article
Rapid and Sensitive Detection of Amino Groups in Chitosan Oligomers Using Aqueous Ninhydrin and McIlvaine Buffer
by Oana Roxana Toader, Bianca-Vanesa Agachi, Andra Olariu, Corina Duda-Seiman, Gheorghita Menghiu and Vasile Ostafe
Molecules 2026, 31(7), 1101; https://doi.org/10.3390/molecules31071101 - 27 Mar 2026
Viewed by 281
Abstract
Chitooligosaccharides (COS) are short-chain chitosan derivatives with a wide range of biomedical, agricultural, and environmental applications, including antimicrobial therapy, wound healing, and pollutant removal. Reliable quantification of COS is essential but currently relies on high-performance liquid chromatography, mass spectrometry, or capillary electrophoresis, which [...] Read more.
Chitooligosaccharides (COS) are short-chain chitosan derivatives with a wide range of biomedical, agricultural, and environmental applications, including antimicrobial therapy, wound healing, and pollutant removal. Reliable quantification of COS is essential but currently relies on high-performance liquid chromatography, mass spectrometry, or capillary electrophoresis, which require costly equipment, complex sample preparation, and are unsuitable for routine or on-site applications. This study reports a rapid, solvent-free, colorimetric assay for COS based on the reaction of 5% aqueous ninhydrin with free amino groups in McIlvaine buffer. The assay was optimized using glucosamine as a model analyte, yielding maximal sensitivity at pH 7.0. The chromophore generated (Ruhemann’s purple) remained stable for over 120 min after reaction, allowing measurements to be taken without strict time constraints. Calibration was linear from 0.4 to 2.2 mM (R2 = 0.9926), with low limits of detection (0.006 mM) and quantification (0.018 mM). Increasing absorbance with COS polymerization degree (DP1–DP6) demonstrates specificity for free amino groups, while N-acetyl glucosamine showed a negligible response. Furthermore, the assay was successfully adapted for solid-phase detection on ninhydrin-pretreated filter paper and nitrocellulose, with enhanced sensitivity. This simple, efficient, and low-cost method provides an accessible alternative to instrumental techniques, supporting COS monitoring in laboratory workflows and enabling portable applications in biomedicine, agriculture, and environmental diagnostics. Full article
(This article belongs to the Special Issue Green Chemistry Approaches to Analysis and Environmental Remediation)
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