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Keywords = quantum Toffoli gate

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21 pages, 1307 KB  
Article
A Quantum Strategy for the Simulation of Large Proteins: From Fragmentation in Small Proteins to Scalability in Complex Systems
by Parfait Atchade-Adelomou and Laia Coronas Sala
Electronics 2025, 14(13), 2601; https://doi.org/10.3390/electronics14132601 - 27 Jun 2025
Cited by 1 | Viewed by 999
Abstract
We present a scalable and resource-aware framework for the quantum simulation of large proteins, grounded in systematic molecular fragmentation, analytical Toffoli gate modeling, and empirical validation. The ground-state energy of a target biomolecule is reconstructed from capped amino acid fragments, with fixed corrections [...] Read more.
We present a scalable and resource-aware framework for the quantum simulation of large proteins, grounded in systematic molecular fragmentation, analytical Toffoli gate modeling, and empirical validation. The ground-state energy of a target biomolecule is reconstructed from capped amino acid fragments, with fixed corrections to account for artificial boundaries. Analytical cost estimates—derived from reduced Hamiltonians—are benchmarked against empirical Toffoli counts using PennyLane’s resource estimation module. Our model maintains predictive accuracy across biologically relevant systems of up to 1852 electrons, capturing consistent patterns across diverse fragments. This framework enables early-stage feasibility assessments for achieving quantum advantage in biochemical simulation pipelines. Full article
(This article belongs to the Special Issue Recent Advances in Quantum Information)
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21 pages, 5152 KB  
Article
Compact 8-Bit S-Boxes Based on Multiplication in a Galois Field GF(24)
by Phuc-Phan Duong, Tuan-Kiet Dang, Trong-Thuc Hoang and Cong-Kha Pham
Cryptography 2025, 9(2), 21; https://doi.org/10.3390/cryptography9020021 - 3 Apr 2025
Cited by 4 | Viewed by 4129
Abstract
Substitution boxes (S-Boxes) function as essential nonlinear elements in contemporary cryptographic systems, offering robust protection against cryptanalytic attacks. This study presents a novel technique for generating compact 8-bit S-Boxes based on multiplication in the Galois Field GF(24). [...] Read more.
Substitution boxes (S-Boxes) function as essential nonlinear elements in contemporary cryptographic systems, offering robust protection against cryptanalytic attacks. This study presents a novel technique for generating compact 8-bit S-Boxes based on multiplication in the Galois Field GF(24). The goal of this method is to create S-Boxes with low hardware implementation cost while ensuring cryptographic properties. Experimental results indicate that the suggested S-Boxes achieve a nonlinearity value of 112, matching the AES S-Box. They also maintain other cryptographic properties, such as the Bit Independence Criterion (BIC), the Strict Avalanche Criterion (SAC), Differential Approximation Probability, and Linear Approximation Probability, within acceptable security thresholds. Notably, compared to existing studies, the proposed S-Box architecture demonstrates enhanced hardware efficiency, significantly reducing resource utilization in implementations. Specifically, the implementation cost of the S-Box consists of 31 XOR gates, 32 two-input AND gates, 6 two-input OR gates, and 2 MUX21s. Moreover, this work provides a thorough assessment of the S-Box, covering cryptographic properties, side channel attacks, and implementation aspects. Furthermore, the study estimates the quantum resource requirements for implementing the S-Box, including an analysis of CNOT, Toffoli, and NOT gate counts. Full article
(This article belongs to the Special Issue Emerging Topics in Hardware Security)
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13 pages, 389 KB  
Article
Quantum Implementation of AIM: Aiming for Low-Depth
by Kyungbae Jang, Yujin Oh, Hyunji Kim and Hwajeong Seo
Appl. Sci. 2024, 14(7), 2824; https://doi.org/10.3390/app14072824 - 27 Mar 2024
Cited by 2 | Viewed by 1808
Abstract
Security vulnerabilities in the symmetric-key primitives of a cipher can undermine the overall security claims of the cipher. With the rapid advancement of quantum computing in recent years, there is an increasing effort to evaluate the security of symmetric-key cryptography against potential quantum [...] Read more.
Security vulnerabilities in the symmetric-key primitives of a cipher can undermine the overall security claims of the cipher. With the rapid advancement of quantum computing in recent years, there is an increasing effort to evaluate the security of symmetric-key cryptography against potential quantum attacks. This paper focuses on analyzing the quantum attack resistance of AIM, a symmetric-key primitive used in the AIMer digital signature scheme. We present the first quantum circuit implementation of AIM and estimate its complexity (such as qubit count, gate count, and circuit depth) with respect to Grover’s search algorithm. For Grover’s key search, the most important optimization metric is depth, especially when considering parallel search. Our implementation gathers multiple methods for a low-depth quantum circuit of AIM in order to reduce the Toffoli depth and full depth (such as the Karatsuba multiplication and optimization of inner modules; MerLinearLayer). Full article
(This article belongs to the Special Issue Advanced Technologies in Data and Information Security III)
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30 pages, 9856 KB  
Article
Mixed Multi-Chaos Quantum Image Encryption Scheme Based on Quantum Cellular Automata (QCA)
by Nehal Abd El-Salam Mohamed, Hala El-Sayed and Aliaa Youssif
Fractal Fract. 2023, 7(10), 734; https://doi.org/10.3390/fractalfract7100734 - 4 Oct 2023
Cited by 29 | Viewed by 3612
Abstract
The advent of quantum computers could enable the resolution of complex computational problems that conventional cryptographic protocols find challenging. As a result, the formidable computing capabilities of quantum computers may render all present-day cryptographic schemes that rely on computational complexity ineffectual. Inspired by [...] Read more.
The advent of quantum computers could enable the resolution of complex computational problems that conventional cryptographic protocols find challenging. As a result, the formidable computing capabilities of quantum computers may render all present-day cryptographic schemes that rely on computational complexity ineffectual. Inspired by these possibilities, the primary purpose of this paper is to suggest a quantum image encryption scheme based on quantum cellular automata with mixed multi-chaos hybrid maps and a hyperchaotic system with quantum operations. To achieve desirable encryption outcomes, we designed an encryption scheme involving two main operations: (1) pixel-level diffusion and (2) pixel-level permutation. Initially, the secret keys generated using the hyperchaotic system were closely tied to the original image. During the first phase, the establishment of correlations among the image pixels, in addition to the three chaotic sequences obtained from the hyperchaotic system, was achieved with the application of a quantum-state superposition and measurement principle, wherein the color information of a pixel is described using a single qubit. Therefore, the three channels of the plain image were subjected to quantum operations, which involve Hadamard transformation and the quantum-controlled NOT gate, before the diffusion of each color channel with the hyperchaotic system. Subsequently, a quantum ternary Toffoli gate was used to perform the diffusion operation. Next, the appropriate measurement was performed on the three diffused channels. To attain the confusion phase, a blend of mixed multi-chaos hybrid maps and a two-dimensional quantum cellular automaton was used to produce random and chaotic sequence keys. Subsequently, the circular shift was utilized to additionally shuffle the rows and columns of the three diffused components, in order to alter the positions of their pixel values, which significantly contributes to the permutation process. Lastly, the three encoding channels, R, G, and B, were merged to acquire the encrypted image. The experimental findings and security analyses established that the designed quantum image encryption scheme possesses excellent encryption efficiency, a high degree of security, and the ability to effectively withstand a diverse variety of statistical attacks. Full article
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11 pages, 1598 KB  
Article
A New Quantum Private Protocol for Set Intersection Cardinality Based on a Quantum Homomorphic Encryption Scheme for Toffoli Gate
by Wen Liu, Yangzhi Li, Zhirao Wang and Yugang Li
Entropy 2023, 25(3), 516; https://doi.org/10.3390/e25030516 - 16 Mar 2023
Cited by 12 | Viewed by 2438
Abstract
Set Intersection Cardinality (SI-CA) computes the intersection cardinality of two parties’ sets, which has many important and practical applications such as data mining and data analysis. However, in the face of big data sets, it is difficult for two parties to execute the [...] Read more.
Set Intersection Cardinality (SI-CA) computes the intersection cardinality of two parties’ sets, which has many important and practical applications such as data mining and data analysis. However, in the face of big data sets, it is difficult for two parties to execute the SI-CA protocol repeatedly. In order to reduce the execution pressure, a Private Set Intersection Cardinality (PSI-CA) protocol based on a quantum homomorphic encryption scheme for the Toffoli gate is proposed. Two parties encode their private sets into two quantum sequences and encrypt their sequences by way of a quantum homomorphic encryption scheme. After receiving the encrypted results, the semi-honest third party (TP) can determine the equality of two quantum sequences with the Toffoli gate and decrypted keys. The simulation of the quantum homomorphic encryption scheme for the Toffoli gate on two quantum bits is given by the IBM Quantum Experience platform. The simulation results show that the scheme can also realize the corresponding function on two quantum sequences. Full article
(This article belongs to the Special Issue New Advances in Quantum Communication and Networks)
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14 pages, 1162 KB  
Article
Quantum Binary Field Multiplication with Optimized Toffoli Depth and Extension to Quantum Inversion
by Kyungbae Jang, Wonwoong Kim, Sejin Lim, Yeajun Kang, Yujin Yang and Hwajeong Seo
Sensors 2023, 23(6), 3156; https://doi.org/10.3390/s23063156 - 15 Mar 2023
Cited by 5 | Viewed by 3652
Abstract
The Shor’s algorithm can find solutions to the discrete logarithm problem on binary elliptic curves in polynomial time. A major challenge in implementing Shor’s algorithm is the overhead of representing and performing arithmetic on binary elliptic curves using quantum circuits. Multiplication of binary [...] Read more.
The Shor’s algorithm can find solutions to the discrete logarithm problem on binary elliptic curves in polynomial time. A major challenge in implementing Shor’s algorithm is the overhead of representing and performing arithmetic on binary elliptic curves using quantum circuits. Multiplication of binary fields is one of the critical operations in the context of elliptic curve arithmetic, and it is especially costly in the quantum setting. Our goal in this paper is to optimize quantum multiplication in the binary field. In the past, efforts to optimize quantum multiplication have centred on reducing the Toffoli gate count or qubits required. However, despite the fact that circuit depth is an important metric for indicating the performance of a quantum circuit, previous studies have lacked sufficient consideration for reducing circuit depth. Our approach to optimizing quantum multiplication differs from previous work in that we aim at reducing the Toffoli depth and full depth. To optimize quantum multiplication, we adopt the Karatsuba multiplication method which is based on the divide-and-conquer approach. In summary, we present an optimized quantum multiplication that has a Toffoli depth of one. Additionally, the full depth of the quantum circuit is also reduced thanks to our Toffoli depth optimization strategy. To demonstrate the effectiveness of our proposed method, we evaluate its performance using various metrics such as the qubit count, quantum gates, and circuit depth, as well as the qubits-depth product. These metrics provide insight into the resource requirements and complexity of the method. Our work achieves the lowest Toffoli depth, full depth, and the best trade-off performance for quantum multiplication. Further, our multiplication is more effective when not used in stand-alone cases. We show this effectiveness by using our multiplication to the Itoh–Tsujii algorithm-based inversion of F(x8+x4+x3+x+1). Full article
(This article belongs to the Collection Cryptography and Security in IoT and Sensor Networks)
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13 pages, 488 KB  
Article
Generalized Toffoli Gate Decomposition Using Ququints: Towards Realizing Grover’s Algorithm with Qudits
by Anstasiia S. Nikolaeva, Evgeniy O. Kiktenko and Aleksey K. Fedorov
Entropy 2023, 25(2), 387; https://doi.org/10.3390/e25020387 - 20 Feb 2023
Cited by 15 | Viewed by 5475
Abstract
Qubits, which are the quantum counterparts of classical bits, are used as basic information units for quantum information processing, whereas underlying physical information carriers, e.g., (artificial) atoms or ions, admit encoding of more complex multilevel states—qudits. Recently, significant attention has been paid to [...] Read more.
Qubits, which are the quantum counterparts of classical bits, are used as basic information units for quantum information processing, whereas underlying physical information carriers, e.g., (artificial) atoms or ions, admit encoding of more complex multilevel states—qudits. Recently, significant attention has been paid to the idea of using qudit encoding as a way for further scaling quantum processors. In this work, we present an efficient decomposition of the generalized Toffoli gate on five-level quantum systems—so-called ququints—that use ququints’ space as the space of two qubits with a joint ancillary state. The basic two-qubit operation we use is a version of the controlled-phase gate. The proposed N-qubit Toffoli gate decomposition has O(N) asymptotic depth and does not use ancillary qubits. We then apply our results for Grover’s algorithm, where we indicate on the sizable advantage of using the qudit-based approach with the proposed decomposition in comparison to the standard qubit case. We expect that our results are applicable for quantum processors based on various physical platforms, such as trapped ions, neutral atoms, protonic systems, superconducting circuits, and others. Full article
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25 pages, 17258 KB  
Article
Novel Quantum-Dot Cellular Automata-Based Gate Designs for Efficient Reversible Computing
by Mohsen Vahabi, Ehsan Rahimi, Pavel Lyakhov, Ali Newaz Bahar, Khan A. Wahid and Akira Otsuki
Sustainability 2023, 15(3), 2265; https://doi.org/10.3390/su15032265 - 26 Jan 2023
Cited by 17 | Viewed by 4344
Abstract
Reversible logic enables ultra-low power circuit design and quantum computation. Quantum-dot Cellular Automata (QCA) is the most promising technology considered to implement reversible circuits, mainly due to the correspondence between features of reversible and QCA circuits. This work aims to push forward the [...] Read more.
Reversible logic enables ultra-low power circuit design and quantum computation. Quantum-dot Cellular Automata (QCA) is the most promising technology considered to implement reversible circuits, mainly due to the correspondence between features of reversible and QCA circuits. This work aims to push forward the state-of-the-art of the QCA-based reversible circuits implementation by proposing a novel QCA design of a reversible full adder\full subtractor (FA\FS). At first, we consider an efficient XOR-gate, and based on this, new QCA circuit layouts of Feynman, Toffoli, Peres, PQR, TR, RUG, URG, RQCA, and RQG are proposed. The efficient XOR gate significantly reduces the required clock phases and circuit area. As a result, all the proposed reversible circuits are efficient regarding cell count, delay, and circuit area. Finally, based on the presented reversible gates, a novel QCA design of a reversible full adder\full subtractor (FA\FS) is proposed. Compared to the state-of-the-art circuits, the proposed QCA design of FA\FS reversible circuit achieved up to 57% area savings, with 46% and 29% reduction in cell number and delay, respectively. Full article
(This article belongs to the Special Issue Sustainable and Optimal Manufacturing)
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24 pages, 9222 KB  
Article
Quantum Algorithm for Variant Maximum Satisfiability
by Abdirahman Alasow, Peter Jin and Marek Perkowski
Entropy 2022, 24(11), 1615; https://doi.org/10.3390/e24111615 - 5 Nov 2022
Cited by 4 | Viewed by 4056
Abstract
In this paper, we proposed a novel quantum algorithm for the maximum satisfiability problem. Satisfiability (SAT) is to find the set of assignment values of input variables for the given Boolean function that evaluates this function as TRUE or prove that such satisfying [...] Read more.
In this paper, we proposed a novel quantum algorithm for the maximum satisfiability problem. Satisfiability (SAT) is to find the set of assignment values of input variables for the given Boolean function that evaluates this function as TRUE or prove that such satisfying values do not exist. For a POS SAT problem, we proposed a novel quantum algorithm for the maximum satisfiability (MAX-SAT), which returns the maximum number of OR terms that are satisfied for the SAT-unsatisfiable function, providing us with information on how far the given Boolean function is from the SAT satisfaction. We used Grover’s algorithm with a new block called quantum counter in the oracle circuit. The proposed circuit can be adapted for various forms of satisfiability expressions and several satisfiability-like problems. Using the quantum counter and mirrors for SAT terms reduces the need for ancilla qubits and realizes a large Toffoli gate that is then not needed. Our circuit reduces the number of ancilla qubits for the terms T of the Boolean function from T of ancilla qubits to log2T+1. We analyzed and compared the quantum cost of the traditional oracle design with our design which gives a low quantum cost. Full article
(This article belongs to the Special Issue Advances in Quantum Computing)
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23 pages, 797 KB  
Article
Optimization of Reversible Circuits Using Toffoli Decompositions with Negative Controls
by Mariam Gado and Ahmed Younes
Symmetry 2021, 13(6), 1025; https://doi.org/10.3390/sym13061025 - 7 Jun 2021
Cited by 6 | Viewed by 6133
Abstract
The synthesis and optimization of quantum circuits are essential for the construction of quantum computers. This paper proposes two methods to reduce the quantum cost of 3-bit reversible circuits. The first method utilizes basic building blocks of gate pairs using different Toffoli decompositions. [...] Read more.
The synthesis and optimization of quantum circuits are essential for the construction of quantum computers. This paper proposes two methods to reduce the quantum cost of 3-bit reversible circuits. The first method utilizes basic building blocks of gate pairs using different Toffoli decompositions. These gate pairs are used to reconstruct the quantum circuits where further optimization rules will be applied to synthesize the optimized circuit. The second method suggests using a new universal library, which provides better quantum cost when compared with previous work in both cost015 and cost115 metrics; this proposed new universal library “Negative NCT” uses gates that operate on the target qubit only when the control qubit’s state is zero. A combination of the proposed basic building blocks of pairs of gates and the proposed Negative NCT library is used in this work for synthesis and optimization, where the Negative NCT library showed better quantum cost after optimization compared with the NCT library despite having the same circuit size. The reversible circuits over three bits form a permutation group of size 40,320 (23!), which is a subset of the symmetric group, where the NCT library is considered as the generators of the permutation group. Full article
(This article belongs to the Section Computer)
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17 pages, 485 KB  
Article
Quantum Circuit Design of Toom 3-Way Multiplication
by Harashta Tatimma Larasati, Asep Muhamad Awaludin, Janghyun Ji and Howon Kim
Appl. Sci. 2021, 11(9), 3752; https://doi.org/10.3390/app11093752 - 21 Apr 2021
Cited by 13 | Viewed by 5545
Abstract
In classical computation, Toom–Cook is one of the multiplication methods for large numbers which offers faster execution time compared to other algorithms such as schoolbook and Karatsuba multiplication. For the use in quantum computation, prior work considered the Toom-2.5 variant rather than the [...] Read more.
In classical computation, Toom–Cook is one of the multiplication methods for large numbers which offers faster execution time compared to other algorithms such as schoolbook and Karatsuba multiplication. For the use in quantum computation, prior work considered the Toom-2.5 variant rather than the classically faster and more prominent Toom-3, primarily to avoid the nontrivial division operations inherent in the latter circuit. In this paper, we investigate the quantum circuit for Toom-3 multiplication, which is expected to give an asymptotically lower depth than the Toom-2.5 circuit. In particular, we designed the corresponding quantum circuit and adopted the sequence proposed by Bodrato to yield a lower number of operations, especially in terms of nontrivial division, which is reduced to only one exact division by 3 circuit per iteration. Moreover, to further minimize the cost of the remaining division, we utilize the unique property of the particular division circuit, replacing it with a constant multiplication by reciprocal circuit and the corresponding swap operations. Our numerical analysis shows that the resulting circuit indeed gives a lower asymptotic complexity in terms of Toffoli depth and qubit count compared to Toom-2.5 but with a large number of Toffoli gates that mainly come from realizing the division operation. Full article
(This article belongs to the Special Issue Quantum Computing and Quantum Information Processing)
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25 pages, 1394 KB  
Article
Grover on Korean Block Ciphers
by Kyoungbae Jang, Seungju Choi, Hyeokdong Kwon, Hyunji Kim, Jaehoon Park and Hwajeong Seo
Appl. Sci. 2020, 10(18), 6407; https://doi.org/10.3390/app10186407 - 14 Sep 2020
Cited by 30 | Viewed by 4184
Abstract
The Grover search algorithm reduces the security level of symmetric key cryptography with n-bit security level to O(2n/2). In order to evaluate the Grover search algorithm, the target block cipher should be efficiently implemented in [...] Read more.
The Grover search algorithm reduces the security level of symmetric key cryptography with n-bit security level to O(2n/2). In order to evaluate the Grover search algorithm, the target block cipher should be efficiently implemented in quantum circuits. Recently, many research works evaluated required quantum resources of AES block ciphers by optimizing the expensive substitute layer. However, few works were devoted to the lightweight block ciphers, even though it is an active research area, nowadays. In this paper, we present optimized implementations of every Korean made lightweight block ciphers for quantum computers, which include HIGHT, CHAM, and LEA, and NSA made lightweight block ciphers, namely SPECK. Primitive operations for block ciphers, including addition, rotation, and exclusive-or, are finely optimized to achieve the optimal quantum circuit, in terms of qubits, Toffoli gate, CNOT gate, and X gate. To the best of our knowledge, this is the first implementation of ARX-based Korean lightweight block ciphers in quantum circuits. Full article
(This article belongs to the Section Quantum Science and Technology)
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17 pages, 386 KB  
Article
Holistic Type Extension for Classical Logic via Toffoli Quantum Gate
by Hector Freytes, Roberto Giuntini and Giuseppe Sergioli
Entropy 2019, 21(7), 636; https://doi.org/10.3390/e21070636 - 27 Jun 2019
Cited by 2 | Viewed by 3198
Abstract
A holistic extension of classical propositional logic is introduced via Toffoli quantum gate. This extension is based on the framework of the so-called “quantum computation with mixed states”, where also irreversible transformations are taken into account. Formal aspects of this new logical system [...] Read more.
A holistic extension of classical propositional logic is introduced via Toffoli quantum gate. This extension is based on the framework of the so-called “quantum computation with mixed states”, where also irreversible transformations are taken into account. Formal aspects of this new logical system are detailed: in particular, the concepts of tautology and contradiction are investigated in this extension. These concepts turn out to receive substantial changes due to the non-separability of some quantum states; as an example, Werner states emerge as particular cases of “holistic” contradiction. Full article
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16 pages, 622 KB  
Proceeding Paper
Interpolating Binary and Multivalued Logical Quantum Gates
by Zeno Toffano and François Dubois
Proceedings 2018, 2(4), 152; https://doi.org/10.3390/ecea-4-05006 - 20 Nov 2017
Cited by 2 | Viewed by 2193
Abstract
A method for synthesizing quantum gates is presented based on interpolation methods applied to operators in Hilbert space. Starting from the diagonal forms of specific generating seed operators with non-degenerate eigenvalue spectrum one obtains for arity-one a complete family of logical operators corresponding [...] Read more.
A method for synthesizing quantum gates is presented based on interpolation methods applied to operators in Hilbert space. Starting from the diagonal forms of specific generating seed operators with non-degenerate eigenvalue spectrum one obtains for arity-one a complete family of logical operators corresponding to all the one-argument logical connectives. Scaling-up to n-arity gates is obtained by using the Kronecker product and unitary transformations. The quantum version of the Fourier transform of Boolean functions is presented and a Reed-Muller decomposition for quantum logical gates is derived. The common control gates can be easily obtained by considering the logical correspondence between the control logic operator and the binary logic operator. A new polynomial and exponential formulation of the Toffoli gate is presented. The method has parallels to quantum gate-T optimization methods using powers of multilinear operator polynomials. The method is then applied naturally to alphabets greater than two for multi-valued logical gates used for quantum Fourier transform, min-max decision circuits and multivalued adders. Full article
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