Search Results (110)

Background/Objectives: Social media popularity and shifting cultural standards of beauty have intensified the growing demand for cosmetic procedures in Saudi Arabia, and body dysmorphic disorder (BDD) has not previously been given due consideration in cosmetic surgery-seeking behavior. This study determined the proportion of females screening positive for BDD and identified its predictors. Participants and methods: The present study employed an analytical cross-sectional design and was conducted from January 2025 to July 2025 in the Dammam region (Eastern) of Saudi Arabia. A validated tool was utilized to assess sociodemographic characteristics, cosmetic surgery history and intentions, social media exposure, and BDD symptoms. We applied a multivariate analysis to identify the predictors. Results: Among the 250 participants, 72 (28.8%) screened positive for BDD. The positive screening for BDD was significantly higher among the participants with a qualification of university and above (ref: up to high school, AOR = 1.291, 95% CI = 1.016–1.667, p = 0.038), who considered cosmetic surgery during their current visit (ref: no, AOR = 3.123, 95% CI = 1.671–4.982, p = 0.001), and more than 3 h use of social media (ref: less than 1 h, AOR = 4.368, 95% CI = 3.570–5.134, p = 0.007). Conclusions: The present findings suggest that a BDD screening program and a multidisciplinary approach are required to ensure ethical practice and to decrease the repeated or unnecessary interventions. Furthermore, future multicenter and mixed-method studies should be conducted to confirm these findings and guide national psychological assessment practices in aesthetic medicine. Full article

The aim of the research was to analyse the impact of peening each of the beads on the properties of a butt joint made of S960QL steel welded with ceramic backing on a robotic workstation using the 135 (MAG) method, and to determine the impact of pneumatic needle peening on the stress level. This analysis was based on a comparison of three butt joints: in the as-welded state, with each weld bead peened and post-weld heat treatment—stress relief annealing—performed. High-frequency peening (90 Hz) of each weld was performed to reduce stresses in the welded joint by introducing tensile stresses into it. A Weld Line 10 pneumatic hammer from PITEC GmBH was used for this purpose. The test joints obtained were tested in accordance with the requirements of EN ISO 15614-1. In order to determine the state of residual stresses, stress measurements were carried out using the Barkhausen effect based on the testing procedure of the technology supplier, NNT. This meter measures the intensity of the Barkhausen effect using a standard probe (with a single core). In order to verify the stress measurement using the Barkhausen method, stress measurements were performed using the XRD sin 2ψ technique based on the X’Pert Stress Plus program, which contains a database of material constants necessary for calculations. Structural studies, including phase analysis and crystallographic grain orientation, were performed using the backscattered electron diffraction method with a high-resolution scanning electron microscope and an EBSD (Electron Backscatter Diffraction) detector, as well as EDAX OIM analysis software. In addition, X-ray diffraction testing was performed on a Panalytical X’Pert PRO device using filtered cobalt anode tube radiation (λ = 1.79021 A). Qualitative X-ray phase analysis of the tested materials was performed in a Bragg–Brentano system using an Xcelerator strip detector. The tests showed that the high-frequency peening of each bead did not cause negative results in the required tests during qualification of the S960QL plate-welding technology compared to the test plates in the as-welded and post-stress-relief heat treatment states. Interpass peening of the weld face and HAZ resulted in a reduction in residual stresses after welding at a distance of 15 mm from the joint axis compared to the stress measurement result for the sample in the as-welded condition. This allows for a positive assessment of peening in terms of reducing the crack initiator in the form of the concentration of tensile stresses in the area of the fusion line and HAZ. Full article

(1) Background: Fiberoptic Endoscopic Evaluation of Swallowing (FEES) is one of the two gold-standard tools for assessing oropharyngeal dysphagia (alongside Videofluoroscopic Swallowing Study). Although generally considered safe, concerns about complications persist, particularly in systems where FEES is not routine and professional roles differ. The aim of this study was to evaluate the safety of FEES performed by both speech-language pathologists (SLPs) and physicians, in order to provide evidence of its safety in a healthcare system where the procedure is not yet widely established and to identify patient subgroups potentially at higher risk of procedure-related complications. (2) Methods: This retrospective study analyzed 964 consecutive FEES procedures. Examinations were carried out by trained SLPs or physicians. Data included demographics, clinical status, operator qualifications, setting, and complications, classified as minor (vomiting, poor tolerance, early termination) or major (laryngospasm, epistaxis). (3) Results: The overall complication rate was 1.14% (11/964): 0.6% minor and 0.5% major. All events were self-limiting. Complication rates did not differ between SLPs (1.05%) and physicians (1.23%) or by experience, setting, drug use, penetration–aspiration scale score, or nasogastric tube. Four complications occurred in amyotrophic lateral sclerosis patients, suggesting higher risk. (4) Conclusions: FEES is safe and well tolerated when performed by either physicians or SLPs. These findings underscore the value of task sharing in dysphagia diagnostics, demonstrating that a shared model increases service capacity, reduces delays, and facilitates timely management of dysphagia. Full article

Ultrasound enhancing agents (UEAs, formerly called contrast agents) have enhanced echocardiographic diagnostics of myocardial disease and masses as well as myocardial perfusion abnormalities. This review provides up-to-date guidance on the procedures and interpretations according to current recommendations of imaging societies and considering the results of recent major studies. For the different indications, a standardized approach has been created including technical aspects, pre-assessment and primary scan planes, contrast-enhanced ultrasound (CEUS) procedure, interpretation and reporting. In a previous publication (part 1) the UEAs, imaging methods, preparation of the patients and assessment of global and regional LV function with UEAs were included. The two parts represent a comprehensive state-of-the-art compendium on how to perform CEUS examinations in clinical echocardiography and provide advice on education, qualification and quality control. Full article

The advent of remote control and autonomous technologies is fundamentally transforming ship manning models, necessitating adaptations in seafarer standards for L2-class autonomous vessels. To address these challenges, the International Maritime Organization’s (IMO) Maritime Safety Committee (MSC) is developing a non-mandatory Code for Maritime Autonomous Surface Ships (MASS). This paper first conducts an in-depth analysis of the immutable legal obligations and variable technical standards governing seafarer manning for L2 autonomous ships, drawing on the China Classification Society’s (CCS) Rules for Intelligent Ships. It then scrutinizes the international legal barriers confronting CCS manning requirements, particularly concerning remote operator qualifications. The study focuses on aligning China’s regulatory framework with emerging IMO standards and proposes four targeted reforms to facilitate this alignment for L2 vessels: broadening the “seafarer” definition, updating minimum manning principles and procedures, modernizing competency standards, and establishing inclusive operational testing systems. Full article

In Italy, the management of built assets confiscated from organized crime groups is particularly relevant. Returning these assets to the community is becoming increasingly important for Italian municipalities, thanks to the many social benefits that can be generated (e.g., new spaces to provide community services, a visible and tangible symbol of legality, etc.). The process of redeveloping confiscated buildings, due to procedural complexity and a lack of resources, is currently characterized, on one hand, by a limited number of projects actually implemented compared to the potential of the total number of buildings available and, on the other hand, by the lengthy duration of the redevelopment process (12 years on average), which significantly increases the time it takes for the asset to return social value to the community. The objective of this research was to study, develop, and describe a mechanism that (i) enables an increase in the number of redevelopment actions of confiscated assets, (ii) accelerates the attribution of social value to these assets over time and (iii) extends the social impact of the requalification interventions that provide an opportunity for the professional training of students and the professional qualification of vulnerable people. There are two main tasks of the research shown in this article: (i) to highlight the main critical issues and needs in the management of confiscated assets by Italian municipalities, through a survey conducted among key informants; (ii) to build and test an innovative ‘win–win model’ for the requalification process of confiscated buildings, aimed at overcoming obstacles and anticipating the delivery of social benefits to a large group of stakeholders, including vulnerable people, tested in a pilot project. This “win–win model” combines building requalification and training through the activation of a “construction site school”. All original contributions are derived from the research “Co-WIN”, funded by the “Polisocial Awards 2021”, which developed methods, strategies, and tools capable of reducing social imbalances, with an equity and sustainability perspective. The results illustrated the drivers and challenges for the renovation and reuse of confiscated built assets; the necessary changes in documents and procedures to activate and replicate the “Co-WIN model”; and a training program for the construction-site school based on the social categories involved. Finally, the discussion highlights the network and the mutual benefits for stakeholders, focusing on the social relevance and social impact achievable through applying the Co-WIN model to the requalification process of confiscated buildings. Full article

The goal of this paper is to evaluate the life of HVDC extruded cables subjected to the extension of qualification test (EQT) load cycles, introduced by Cigrè Technical Brochure 852, as well as to compare the results thus obtained with those formerly obtained by the authors in the case of the prequalification test (PQT) load cycles. This goal has been achieved in the present investigation by properly modifying a previously developed procedure for the life and reliability estimation of HVDC cables—implemented in Matlab^TM environment—to make it applicable to EQT load cycles in addition to PQT and type test load cycles, which are already considered in the former version of the procedure. Considering a 500 kV DC-XLPE cable as the case study, the time-varying temperature profile and electric field profile within the cable insulation are calculated. Then, the fractions of life lost and the life of the cable at five locations within the insulation thickness are evaluated by means of a proper electrothermal life model. A comparison between the electric field distributions, fractions of life lost, and cable life under EQT and PQT is carried out. In this way, important features of the EQT compared to the PQT load cycles are singled out, and eventually, a new modified extension of qualification test (MEQT) is proposed as a feasible and meaningful compromise between the pros and cons of the EQT and PQT. Full article

Objective: Current good manufacturing practice (cGMP) guidance for positron emission tomography (PET) drugs has been established in Europe and the United States. In Japan, the Pharmaceuticals and Medical Devices Agency (PMDA) approved the use of radiosynthesizers as medical devices for the in-house manufacturing of PET drugs in hospitals and clinics, regardless of the cGMP environment. Without adequate facilities, equipment, and personnel required by cGMP regulations, the quality assurance (QA) and clinical effectiveness of PET drugs largely depend on the radiosynthesizers themselves. To bridge the gap between radiochemistry standardization and site qualification, the Japanese Society of Nuclear Medicine (JSNM) has issued guidance for the in-house manufacturing of small-scale PET drugs under academic GMP (a-GMP) environments. The goals of cGMP and a-GMP are different: cGMP focuses on process optimization, certification, and commercialization, while a-GMP facilitates the small-scale, in-house production of PET drugs for clinical trials and patient-specific standard of care. Among PET isotopes, N-13 has a short half-life (10 min) and must be synthesized on site. [¹³N]Ammonia ([¹³N]NH₃) is used for myocardial perfusion imaging under the Japan Health Insurance System (JHIS) and was thus selected as a working example for the manufacturing of PET drugs in an a-GMP environment. Methods: A [¹³N]NH₃-radiosynthesizer was installed in a hot cell within an a-GMP-compliant radiopharmacy unit. To comply with a-GMP regulations, the air flow was adjusted through HEPA filters. All cabinets and cells were disinfected to ensure sterility once a month. Standard operating procedures (SOPs) were applied, including analytical methods. Batch records, QA data, and radiation exposure to staff in the synthesis of [¹³N]NH₃ were measured and documented. Results: 2.52 GBq of [¹³N]NH₃ end-of-synthesis (EOS) was obtained in an average of 13.5 min in 15 production runs. The radiochemical purity was more than 99%. Exposure doses were 11 µSv for one production run and 22 µSv for two production runs. The pre-irradiation background dose rate was 0.12 µSv/h. After irradiation, the exposed dosage in the front of the hot cell was 0.15 µSv/h. The leakage dosage measured at the bench was 0.16 µSv/h. The exposure and leakage dosages in the manufacturing of [¹³N]NH₃ were similar to the background level as measured by radiation monitoring systems in an a-GMP environments. All QAs, environmental data, bacteria assays, and particulates met a-GMP compliance standards. Conclusions: In-house a-GMP environments require dedicated radiosynthesizers, documentation for batch records, validation schedules, radiation protection monitoring, air and particulate systems, and accountable personnel. In this study, the in-house manufacturing of [¹³N]NH₃ under a-GMP conditions was successfully demonstrated. These findings support the international harmonization of small-scale PET drug manufacturing in hospitals and clinics for future multi-center clinical trials and the development of a standard of care. Full article

Traditionally, qualifications and skills developed through formal learning have been the cornerstone of enhancing the employability of young people. However, the trajectory from education to work in contemporary society is far from linear; hence, the purpose of this paper is to evidence the potential benefits that non-formal educational practices, specifically involving sport-based interventions (SBIs), may offer to support the transition to employment. This paper presents data from 19 semi-structured interviews that were conducted with participants from organisations that either designed and/or delivered SBIs focused on enhancing employability or were from organisations that had experience of commissioning or funding sport-based employability projects. This paper outlines why SBIs may offer an effective alternative form of education to employment provision and also how SBIs enable young people to navigate non-linear education to employment transitions. Crucial to enhancing this transition is the provision of a supportive and inclusive non-formal educational environment where young people can acquire both propositional and procedural knowledge, whilst concurrently (re)connecting them with formal educational systems to expedite the transition to work. Importantly, this paper highlights that this concurrent blend of non-formal and formal education is particularly critical for young people without formal qualifications and who are furthest from an employment destination. Full article

The literature shows that women persistently earn less than men for similar roles and qualifications; yet, pharmacy has been portrayed as an egalitarian profession, with a small gender earnings gap relative to other occupations. There is a lack of recent studies, and some evidence suggests a significant gender gap when earnings are estimated separately for male and female pharmacists. This study compared the nature and magnitude of gender income disparities using two alternative methodological procedures and evaluated the evidence for policy implications. The study was based on 2019–2022 American Community Survey (ACS) data collected by the U.S. Census Bureau. The sample consisted of 12,450 pharmacists (61.5% women) ages 25–64 years practicing in the U.S. Ordinary least-squares models calculated pharmacist annual incomes as functions of work input, human-capital, and job-related covariates. Results estimated a gender earnings gap of up to 18.6%. Differences across sociodemographic groups suggested that pharmacy is only friendly to selected segments of the profession. The empirical evidence reported here is expected to be used by healthcare managers and policymakers to inform ongoing discussion regarding the need for policy changes and cultural shifts to promote gender equity. Full article

SHEDs have demonstrated significant potential in cell therapy due to their superior proliferation rate, self-renewal and differentiation capacity (particularly neurogenesis attributed to their neural crest origin), and the less invasive procedure required for tissue collection compared to other stem cells. However, there is no established criterion to verify the minimum qualification to select one from numerous candidates, especially for SHEDs’ cultured FBS-free medium for clinic application. For that, we performed a characteristic analysis containing the growth rate, colony-forming unit (CFU) number, average colony size, and migration capacity with hPL-cultured SHEDs from 21 different donors, and we suggest the result as a minimum standard to filter out unqualified candidates. In addition, in the secretome analysis to predict the paracrine effect, it was found that upregulated proteins compared to the control were related to angiogenesis, immune response, and BMP signaling, and this was found to have a strong correlation only with protein concentration. This study presents a minimum standard for selecting cell therapy candidates and suggests the protein concentration of a conditioned medium as a cost-effective tool to expect the paracrine effect of SHEDs. Full article

Conventional Applicant Tracking Systems (ATSs) encounter considerable constraints in accurately aligning resumes with job descriptions (JD), especially in handling unstructured data and intricate qualifications. We provide Resume2Vec, an innovative method that utilizes transformer-based deep learning models, including encoders (BERT, RoBERTa, and DistilBERT) and decoders (GPT, Gemini, and Llama), to create embeddings for resumes and job descriptions, employing cosine similarity for evaluation. Our methodology integrates quantitative analysis via embedding-based evaluation with qualitative human assessment across several professional fields. Experimental findings indicate that Resume2Vec outperformed conventional ATS systems, achieving enhancements of up to 15.85% in Normalized Discounted Cumulative Gain (nDCG) and 15.94% in Ranked Biased Overlap (RBO) scores, especially within the mechanical engineering and health and fitness domains. Although conventional the ATS exhibited slightly superior nDCG scores in operations management and software testing, Resume2Vec consistently displayed a more robust alignment with human preferences across the majority of domains, as indicated by the RBO metrics. This research demonstrates that Resume2Vec is a powerful and scalable method for matching resumes to job descriptions, effectively overcoming the shortcomings of traditional systems, while preserving a high alignment with human evaluation criteria. The results indicate considerable promise for transformer-based methodologies in enhancing recruiting technology, facilitating more efficient and precise candidate selection procedures. Full article

Background/Objectives: The prison environment is a unique context of professional practice, characterized by specific challenges requiring conditions that ensure both the delivery of tailored care to inmates and the well-being of healthcare professionals. This study analyzes the characteristics of nursing practice environments in Portuguese prisons. Methods: A descriptive, exploratory, mixed-methods design, combining quantitative and qualitative approaches was conducted in 30 Portuguese prisons. A non-probabilistic convenience sampling method was used to select participants. Data were collected between June and July 2022 using an online self-administered questionnaire. The Statistical Package for the Social Sciences (SPSS), version 28.0, was used to analyze the quantitative data, while Bardin’s Thematic Analysis was used to examine the qualitative data. The Ethics Committee granted ethical approval for the study, and the Directorate-General for Reintegration and Prison Services provided authorization. Results: A total of 77 nurses participated in the study, representing 39.4% of the target population. The dimensions with the lowest mean scores included “Nurses’ participation and involvement in institutional policies, strategies, and management”, “Institutional policy for professional qualification”, “Interdependent practices in professional activities”, and “Systematic assessment of nurses’ performance and supervision”. Participants highlighted the need for improved strategies targeting structural, procedural, and outcome-oriented components. Conclusions: Finding fields of weakness can greatly enhance the setting for nursing practices. Priority interventions in Portuguese prisons include the following: enhancing human resources; providing adequate infrastructure and equipment; implementing policies to involve, qualify, and assess nurses’ performance; and defining indicators centered on the safety and quality of care as well as the welfare of professionals. Full article

Objectives: Parenteral drug products manufactured under GMP conditions should be visually inspected for defects and particulate contamination by trained and qualified personnel. Although personnel qualification is required, no practical protocols or formal guidelines are available for the development of qualification test sets (QTSs) used for qualification procedures. The current practice is to either procure a standardized QTS from a commercial supplier or amass sufficient manufacturing rejects during visual inspection procedures to compile in-house QTSs. However, both strategies inherently possess disadvantages and limitations. The objective of this study was to develop a manufacturing protocol for an optimal and adaptable QTS for training and qualification procedures. Methods: We combined the results of a literature search, survey of five Dutch hospital pharmacy compounding facilities, semi-structured personnel interviews, and extensive pre-GMP formulation studies to develop an optimal and adaptable QTS manufacturing protocol. Results: The literature search did not identify a manufacturing protocol for an optimal and adaptable QTS, but did identify specifications and requirements for optimal QTSs. The survey among hospital pharmacy compounding facilities revealed considerable variability in the qualification procedures and used QTSs. Semi-structured personnel interviews and pre-GMP formulation studies demonstrated that defects encountered during routine productions could be realistically simulated with pharmaceutical-grade excipients. As a proof-of-concept, we manufactured two different QTSs under GMP conditions and assessed these for formal GMP training and qualification purposes, which were considered a significant improvement compared to using manufacturing rejects. Conclusions: To the best of our knowledge, this is the first study presenting these data and our adaptable protocol, which is provided in the Supplemental Materials, may aid compounding facilities in the standardization, training, and qualification of personnel involved in visual inspection procedures. Full article