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16 pages, 3217 KiB  
Article
Application of an Orbital Remote Sensing Vegetation Index for Urban Tree Cover Mapping to Support the Tree Census
by Cássio Filipe Vieira Martins, Franciele Caroline Guerra, Anderson Targino da Silva Ferreira and Roger Dias Gonçalves
Earth 2025, 6(3), 87; https://doi.org/10.3390/earth6030087 (registering DOI) - 1 Aug 2025
Abstract
Urban vegetation monitoring is essential for sustainable city planning but is often constrained by the high cost and limited frequency of field-based inventories. This study evaluates the use of the Normalized Difference Vegetation Index (NDVI), derived from Sino-Brazilian CBERS-4A satellite imagery, as a [...] Read more.
Urban vegetation monitoring is essential for sustainable city planning but is often constrained by the high cost and limited frequency of field-based inventories. This study evaluates the use of the Normalized Difference Vegetation Index (NDVI), derived from Sino-Brazilian CBERS-4A satellite imagery, as a spatially explicit and low-cost proxy for urban tree census data. CBERS-4A provides medium-resolution multispectral data freely accessible across South America, yet remains underutilized in urban environmental applications. Focusing on Aracaju, a metropolitan region in northeastern Brazil, we compared NDVI-based classification results with official municipal tree census data from 2022. The analysis revealed a strong spatial correlation, supporting the use of NDVI as a reliable indicator of canopy presence at the urban block scale. In addition to mapping vegetation distribution, the NDVI results identified areas with insufficient canopy coverage, directly informing urban greening priorities. By validating remote sensing data against field inventories, this study demonstrates how CBERS-4A imagery and vegetation indices can support municipal tree management and serve as scalable tools for environmental planning and policy. Full article
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28 pages, 7617 KiB  
Article
Using Circuit Theory to Identify Important Ecological Corridors for Large Mammals Between Wildlife Refuges
by Büşra Kalleci and Özkan Evcin
Diversity 2025, 17(8), 542; https://doi.org/10.3390/d17080542 (registering DOI) - 1 Aug 2025
Abstract
Habitat fragmentation restricts the movement of large mammals across broad landscapes, leading to isolation of individuals or groups, reduced interaction with other species, and limited access to vital resources in surrounding habitats. In this study, we aimed to determine the wildlife ecological corridors [...] Read more.
Habitat fragmentation restricts the movement of large mammals across broad landscapes, leading to isolation of individuals or groups, reduced interaction with other species, and limited access to vital resources in surrounding habitats. In this study, we aimed to determine the wildlife ecological corridors for five large mammals (Ursus arctos, Cervus elaphus, Capreolus capreolus, Sus scrofa, and Canis lupus) between Kastamonu Ilgaz Mountain Wildlife Refuge and Gavurdağı Wildlife Refuge. In the field studies, we used the transect, indirect observation, and camera-trap methods to collect presence data. Maximum Entropy (MaxEnt) (v. 3.4.1) software was used to create habitat suitability models of the target species, which are based on the presence-only data approach. The results indicated that AUC values varied between 0.808 and 0.835, with water sources, stand type, and slope contributing most significantly to model performance. In order to determine wildlife ecological corridors, resistance surface maps were created using the species distribution models (SDMs), and bottleneck areas were determined. The Circuit Theory approach was used to model the connections between ecological corridors. As a result of this study, we developed connectivity models for five large mammals based on Circuit Theory, identified priority wildlife ecological corridors, and evaluated critical connection points between two protected areas, Ilgaz Mountain Wildlife Refuge and Gavurdağı Wildlife Refuge. These findings highlight the essential role of ecological corridors in sustaining landscape-level connectivity and supporting the long-term conservation of wide-ranging species. Full article
(This article belongs to the Special Issue Habitat Assessment and Conservation Strategies)
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24 pages, 624 KiB  
Systematic Review
Integrating Artificial Intelligence into Perinatal Care Pathways: A Scoping Review of Reviews of Applications, Outcomes, and Equity
by Rabie Adel El Arab, Omayma Abdulaziz Al Moosa, Zahraa Albahrani, Israa Alkhalil, Joel Somerville and Fuad Abuadas
Nurs. Rep. 2025, 15(8), 281; https://doi.org/10.3390/nursrep15080281 (registering DOI) - 31 Jul 2025
Abstract
Background: Artificial intelligence (AI) and machine learning (ML) have been reshaping maternal, fetal, neonatal, and reproductive healthcare by enhancing risk prediction, diagnostic accuracy, and operational efficiency across the perinatal continuum. However, no comprehensive synthesis has yet been published. Objective: To conduct a scoping [...] Read more.
Background: Artificial intelligence (AI) and machine learning (ML) have been reshaping maternal, fetal, neonatal, and reproductive healthcare by enhancing risk prediction, diagnostic accuracy, and operational efficiency across the perinatal continuum. However, no comprehensive synthesis has yet been published. Objective: To conduct a scoping review of reviews of AI/ML applications spanning reproductive, prenatal, postpartum, neonatal, and early child-development care. Methods: We searched PubMed, Embase, the Cochrane Library, Web of Science, and Scopus through April 2025. Two reviewers independently screened records, extracted data, and assessed methodological quality using AMSTAR 2 for systematic reviews, ROBIS for bias assessment, SANRA for narrative reviews, and JBI guidance for scoping reviews. Results: Thirty-nine reviews met our inclusion criteria. In preconception and fertility treatment, convolutional neural network-based platforms can identify viable embryos and key sperm parameters with over 90 percent accuracy, and machine-learning models can personalize follicle-stimulating hormone regimens to boost mature oocyte yield while reducing overall medication use. Digital sexual-health chatbots have enhanced patient education, pre-exposure prophylaxis adherence, and safer sexual behaviors, although data-privacy safeguards and bias mitigation remain priorities. During pregnancy, advanced deep-learning models can segment fetal anatomy on ultrasound images with more than 90 percent overlap compared to expert annotations and can detect anomalies with sensitivity exceeding 93 percent. Predictive biometric tools can estimate gestational age within one week with accuracy and fetal weight within approximately 190 g. In the postpartum period, AI-driven decision-support systems and conversational agents can facilitate early screening for depression and can guide follow-up care. Wearable sensors enable remote monitoring of maternal blood pressure and heart rate to support timely clinical intervention. Within neonatal care, the Heart Rate Observation (HeRO) system has reduced mortality among very low-birth-weight infants by roughly 20 percent, and additional AI models can predict neonatal sepsis, retinopathy of prematurity, and necrotizing enterocolitis with area-under-the-curve values above 0.80. From an operational standpoint, automated ultrasound workflows deliver biometric measurements at about 14 milliseconds per frame, and dynamic scheduling in IVF laboratories lowers staff workload and per-cycle costs. Home-monitoring platforms for pregnant women are associated with 7–11 percent reductions in maternal mortality and preeclampsia incidence. Despite these advances, most evidence derives from retrospective, single-center studies with limited external validation. Low-resource settings, especially in Sub-Saharan Africa, remain under-represented, and few AI solutions are fully embedded in electronic health records. Conclusions: AI holds transformative promise for perinatal care but will require prospective multicenter validation, equity-centered design, robust governance, transparent fairness audits, and seamless electronic health record integration to translate these innovations into routine practice and improve maternal and neonatal outcomes. Full article
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24 pages, 1386 KiB  
Article
Assessing Sustainable Growth: Evolution and Convergence of Green Total Factor Productivity in Tibetan Plateau Agriculture
by Mengmeng Zhang and Chengqun Yu
Sustainability 2025, 17(15), 6963; https://doi.org/10.3390/su17156963 (registering DOI) - 31 Jul 2025
Abstract
Accurate assessment of green productivity is essential for advancing sustainable agriculture in ecologically fragile regions. This study examined the evolution of agricultural green total factor productivity (AGTFP) in Tibet over the period 2002–2021 by applying a super-efficiency SBM-GML model that accounts for undesirable [...] Read more.
Accurate assessment of green productivity is essential for advancing sustainable agriculture in ecologically fragile regions. This study examined the evolution of agricultural green total factor productivity (AGTFP) in Tibet over the period 2002–2021 by applying a super-efficiency SBM-GML model that accounts for undesirable outputs. We decompose AGTFP into technical change and efficiency change, conduct redundancy analysis to identify sources of inefficiency and explore its spatiotemporal dynamics through kernel density estimation and convergence analysis. Results show that (1) AGTFP in Tibet grew at an average annual rate of 0.78%, slower than the national average of 1.6%; (2) labor input, livestock scale, and agricultural carbon emissions are major sources of redundancy, especially in pastoral regions; (3) technological progress is the main driver of AGTFP growth, while efficiency gains have a limited impact, reflecting a technology-led growth pattern; (4) AGTFP follows a “convergence-divergence-reconvergence” trend, with signs of conditional β convergence after controlling for regional heterogeneity. These findings highlight the need for region-specific green agricultural policies. Priority should be given to improving green technology diffusion and input allocation in high-altitude pastoral areas, alongside strengthening ecological compensation and interregional coordination to enhance green efficiency and promote high-quality development across Tibet. Full article
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23 pages, 4161 KiB  
Article
Scenario-Based Assessment of Urbanization-Induced Land-Use Changes and Regional Habitat Quality Dynamics in Chengdu (1990–2030): Insights from FLUS-InVEST Modeling
by Zhenyu Li, Yuanting Luo, Yuqi Yang, Yuxuan Qing, Yuxin Sun and Cunjian Yang
Land 2025, 14(8), 1568; https://doi.org/10.3390/land14081568 - 31 Jul 2025
Abstract
Against the backdrop of rapid urbanization in western China, which has triggered remarkable land-use changes and habitat degradation, Chengdu, as a developed city in China, plays a demonstrative and leading role in the economic and social development of China during the transition period. [...] Read more.
Against the backdrop of rapid urbanization in western China, which has triggered remarkable land-use changes and habitat degradation, Chengdu, as a developed city in China, plays a demonstrative and leading role in the economic and social development of China during the transition period. Therefore, integrated modeling approaches are required to balance development and conservation. This study responds to this need by conducting a scenario-based assessment of urbanization-induced land-use changes and regional habitat quality dynamics in Chengdu (1990–2030), using the FLUS-InVEST model. By integrating remote sensing-derived land-use data from 1990, 1995, 2000, 2005, 2010, 2015, and 2020, we simulate future regional habitat quality under three policy scenarios: natural development, ecological priority, and cropland protection. Key findings include the following: (1) From 1990 to 2020, cropland decreased by 1917.78 km2, while forestland and built-up areas increased by 509.91 km2 and 1436.52 km2, respectively. Under the 2030 natural development scenario, built-up expansion and cropland reduction are projected. Ecological priority policies would enhance forestland (+4.2%) but slightly reduce cropland. (2) Regional habitat quality declined overall (1990–2020), with the sharpest drop (ΔHQ = −0.063) occurring between 2000 and 2010 due to accelerated urbanization. (3) Scenario analysis reveals that the ecological priority strategy yields the highest regional habitat quality (HQmean = 0.499), while natural development results in the lowest (HQmean = 0.444). This study demonstrates how the FLUS-InVEST model can quantify the trade-offs between urbanization and regional habitat quality, offering a scientific framework for balancing development and ecological conservation in rapidly urbanizing regions. The findings highlight the effectiveness of ecological priority policies in mitigating habitat degradation, with implications for similar cities seeking sustainable land-use strategies that integrate farmland protection and forest restoration. Full article
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23 pages, 1929 KiB  
Article
Emerging Contaminants in Coastal Landscape Park, South Baltic Sea Region: Year-Round Monitoring of Treated Wastewater Discharge into Czarna Wda River
by Emilia Bączkowska, Katarzyna Jankowska, Wojciech Artichowicz, Sylwia Fudala-Ksiazek and Małgorzata Szopińska
Resources 2025, 14(8), 123; https://doi.org/10.3390/resources14080123 - 29 Jul 2025
Viewed by 144
Abstract
In response to the European Union’s revised Urban Wastewater Treatment Directive, which mandates enhanced monitoring and advanced treatment of micropollutants, this study was conducted. It took place within the Coastal Landscape Park (CLP), a Natura 2000 protected area in northern Poland. The focus [...] Read more.
In response to the European Union’s revised Urban Wastewater Treatment Directive, which mandates enhanced monitoring and advanced treatment of micropollutants, this study was conducted. It took place within the Coastal Landscape Park (CLP), a Natura 2000 protected area in northern Poland. The focus was on the municipal wastewater treatment plant in Jastrzębia Góra, located in a region exposed to seasonal tourist pressure and discharging effluent into the Czarna Wda River. A total of 90 wastewater samples were collected during five monitoring campaigns (July, September 2021; February, May, July 2022) and analysed for 13 pharmaceuticals and personal care products (PPCPs) using ultra-high-performance liquid chromatography tandem mass spectrometry with electrospray ionisation (UHPLC-ESI-MS/MS). The monitoring included both untreated (UTWW) and treated wastewater (TWW) to assess the PPCP removal efficiency and persistence. The highest concentrations in the treated wastewater were observed for metoprolol (up to 472.9 ng/L), diclofenac (up to 3030 ng/L), trimethoprim (up to 603.6 ng/L) and carbamazepine (up to 2221 ng/L). A risk quotient (RQ) analysis identified diclofenac and LI-CBZ as priority substances for monitoring. Multivariate analyses (PCA, HCA) revealed co-occurrence patterns and seasonal trends. The results underline the need for advanced treatment solutions and targeted monitoring, especially in sensitive coastal catchments with variable micropollutant presence. Full article
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34 pages, 56730 KiB  
Article
Land Consolidation Potential Assessment by Using the Production–Living–Ecological Space Framework in the Guanzhong Plain, China
by Ziyi Xie, Siying Wu, Xin Liu, Hejia Shi, Mintong Hao, Weiwei Zhao, Xin Fu and Yepeng Liu
Sustainability 2025, 17(15), 6887; https://doi.org/10.3390/su17156887 - 29 Jul 2025
Viewed by 132
Abstract
Land consolidation (LC) is a sustainability-oriented policy tool designed to address land fragmentation, inefficient spatial organization, and ecological degradation in rural areas. This research proposes a Production–Living–Ecological (PLE) spatial utilization efficiency evaluation system, based on an integrated methodological framework combining Principal Component Analysis [...] Read more.
Land consolidation (LC) is a sustainability-oriented policy tool designed to address land fragmentation, inefficient spatial organization, and ecological degradation in rural areas. This research proposes a Production–Living–Ecological (PLE) spatial utilization efficiency evaluation system, based on an integrated methodological framework combining Principal Component Analysis (PCA), Entropy Weight Method (EWM), Attribute-Weighting Method (AWM), Linear Weighted Sum Method (LWSM), Threshold-Verification Coefficient Method (TVCM), Jenks Natural Breaks (JNB) classification, and the Obstacle Degree Model (ODM). The framework is applied to Qian County, located in the Guanzhong Plain in Shaanxi Province. The results reveal three key findings: (1) PLE efficiency exhibits significant spatial heterogeneity. Production efficiency shows a spatial pattern characterized by high values in the central region that gradually decrease toward the surrounding areas. In contrast, the living efficiency demonstrates higher values in the eastern and western regions, while remaining relatively low in the central area. Moreover, ecological efficiency shows a marked advantage in the northern region, indicating a distinct south–north gradient. (2) Integrated efficiency consolidation potential zones present distinct spatial distributions. Preliminary consolidation zones are primarily located in the western region; priority zones are concentrated in the south; and intensive consolidation zones are clustered in the central and southeastern areas, with sporadic distributions in the west and north. (3) Five primary obstacle factors hinder land use efficiency: intensive utilization of production land (PC1), agricultural land reutilization intensity (PC2), livability of living spaces (PC4), ecological space security (PC7), and ecological space fragmentation (PC8). These findings provide theoretical insights and practical guidance for formulating tar-gated LC strategies, optimizing rural spatial structures, and advancing sustainable development in similar regions. Full article
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23 pages, 3831 KiB  
Article
Functional Connectivity in Future Land-Use Change Scenarios as a Tool for Assessing Priority Conservation Areas for Key Bird Species: A Case Study from the Chaco Serrano
by Julieta Rocío Arcamone, Luna Emilce Silvetti, Laura Marisa Bellis, Carolina Baldini, María Paula Alvarez, María Cecilia Naval-Fernández, Jimena Victoria Albornoz and Gregorio Gavier Pizarro
Sustainability 2025, 17(15), 6874; https://doi.org/10.3390/su17156874 - 29 Jul 2025
Viewed by 155
Abstract
Planning conservation for multiple species while accounting for habitat availability and connectivity under uncertain land-use changes presents a major challenge. This study proposes a protocol to identify strategic conservation areas by assessing the functional connectivity of key bird species under future land-use scenarios [...] Read more.
Planning conservation for multiple species while accounting for habitat availability and connectivity under uncertain land-use changes presents a major challenge. This study proposes a protocol to identify strategic conservation areas by assessing the functional connectivity of key bird species under future land-use scenarios in the Chaco Serrano of Córdoba, Argentina. We modeled three land-use scenarios for 2050: business as usual, sustainability, and intensification. Using the Equivalent Connected Area index, we evaluated functional connectivity for Chlorostilbon lucidus, Polioptila dumicola, Dryocopus schulzii, Milvago chimango, and Saltator aurantiirostris for 1989, 2019, and 2050, incorporating information about habitat specialization and dispersal capacity to reflect differences in ecological responses. All species showed declining connectivity from 1989 to 2019, with further losses expected under future scenarios. Connectivity declines varied by species and were not always proportional to habitat loss, highlighting the complex relationship between land-use change and functional connectivity. Surprisingly, the sustainability scenario led to the greatest losses in connectivity, emphasizing that habitat preservation alone does not ensure connectivity. Using the Integral Connectivity Index, we identified habitat patches critical for maintaining connectivity, particularly those vulnerable under the business as usual scenario. With a spatial prioritization analysis we identified priority conservation areas to support future landscape connectivity. These findings underscore the importance of multispecies, connectivity-based planning and offer a transferable framework applicable to other regions. Full article
(This article belongs to the Special Issue Landscape Connectivity for Sustainable Biodiversity Conservation)
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41 pages, 1344 KiB  
Article
Strengthening Smart Specialisation Strategies (S3) Through Network Analysis: Policy Insights from a Decade of Innovation Projects in Aragón
by David Rodríguez Ochoa, Nieves Arranz and Marta Fernandez de Arroyabe
Economies 2025, 13(8), 218; https://doi.org/10.3390/economies13080218 - 26 Jul 2025
Viewed by 224
Abstract
This paper applies a multi-level social network analysis to examine Aragón’s innovation ecosystem, focusing on a decade of competitive public projects (2014–2023) aligned with the region’s Smart Specialisation Strategy (S3) 2021–2027. By mapping and weighting the participation of regional entities across regional, national, [...] Read more.
This paper applies a multi-level social network analysis to examine Aragón’s innovation ecosystem, focusing on a decade of competitive public projects (2014–2023) aligned with the region’s Smart Specialisation Strategy (S3) 2021–2027. By mapping and weighting the participation of regional entities across regional, national, and European calls, the study uncovers how all types of local actors organise themselves around key specialisation areas. Moreover, a comparative benchmark is introduced by analysing more than 33,000 Horizon 2020 and Horizon Europe initiatives without Aragonese partners, revealing how to fill structural gaps and enrich the regional ecosystem through international collaboration. Results show strong funding concentration in four fields—Energy, Health, Agri-Food, and Advanced Technologies—while other historically strategic areas like Hydrogen and Water remain underrepresented. Although leading institutions (UNIZAR, CIRCE, ITA, AITIIP) play central roles in connecting academia and industry, direct collaboration among them is limited, pointing to missed synergies. Expanding previous SNA-based assessments, this study introduces a diagnostic tool to guide policy, proposing targeted actions such as challenge-driven calls, dedicated support programs, and cross-border consortia with top EU partners. Applied to two contrasting specialisation areas, the method offers sector-specific recommendations, helping policymakers align Aragón’s innovation capabilities with EU priorities and strengthen its position in both established and emerging domains. Full article
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17 pages, 1742 KiB  
Article
Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions
by Nurlan Zhangabay, Aizhan Zhangabay, Kenzhebek Akmalaiuly, Akmaral Utelbayeva and Bolat Duissenbekov
Buildings 2025, 15(15), 2637; https://doi.org/10.3390/buildings15152637 - 25 Jul 2025
Viewed by 272
Abstract
Creating a comfortable microclimate in the premises of buildings is currently becoming one of the priorities in the field of architecture, construction and engineering systems. The increased attention from the scientific community to this topic is due not only to the desire to [...] Read more.
Creating a comfortable microclimate in the premises of buildings is currently becoming one of the priorities in the field of architecture, construction and engineering systems. The increased attention from the scientific community to this topic is due not only to the desire to ensure healthy and favorable conditions for human life but also to the need for the rational use of energy resources. This area is becoming particularly relevant in the context of global challenges related to climate change, rising energy costs and increased environmental requirements. Practice shows that any technical solutions to ensure comfortable temperature, humidity and air exchange in rooms should be closely linked to the concept of energy efficiency. This allows one not only to reduce operating costs but also to significantly reduce greenhouse gas emissions, thereby contributing to sustainable development and environmental safety. In this connection, this study presents a parametric assessment of the influence of climatic and geometric factors on the aerodynamic characteristics of the air cavity, which affect the heat exchange process in the ventilated layer of curtain wall systems. The assessment was carried out using a combined analytical calculation method that provides averaged thermophysical parameters, such as mean air velocity (Vs), average internal surface temperature (tin.sav), and convective heat transfer coefficient (αs) within the air cavity. This study resulted in empirical average values, demonstrating that the air velocity within the cavity significantly depends on atmospheric pressure and façade height difference. For instance, a 10-fold increase in façade height leads to a 4.4-fold increase in air velocity. Furthermore, a three-fold variation in local resistance coefficients results in up to a two-fold change in airflow velocity. The cavity thickness, depending on atmospheric pressure, was also found to affect airflow velocity by up to 25%. Similar patterns were observed under ambient temperatures of +20 °C, +30 °C, and +40 °C. The analysis confirmed that airflow velocity is directly affected by cavity height, while the impact of solar radiation is negligible. However, based on the outcomes of the analytical model, it was concluded that the method does not adequately account for the effects of solar radiation and vertical temperature gradients on airflow within ventilated façades. This highlights the need for further full-scale experimental investigations under hot climate conditions in South Kazakhstan. The findings are expected to be applicable internationally to regions with comparable climatic characteristics. Ultimately, a correct understanding of thermophysical processes in such structures will support the advancement of trends such as Lightweight Design, Functionally Graded Design, and Value Engineering in the development of curtain wall systems, through the optimized selection of façade configurations, accounting for temperature loads under specific climatic and design conditions. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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13 pages, 1388 KiB  
Article
Indazole Derivatives Against Murine Cutaneous Leishmaniasis
by Niurka Mollineda-Diogo, Yunierkis Pérez-Castillo, Sergio Sifontes-Rodríguez, Osmani Marrero-Chang, Alfredo Meneses-Marcel, Alma Reyna Escalona-Montaño, María Magdalena Aguirre-García, Teresa Espinosa-Buitrago, Yeny Morales-Moreno and Vicente Arán-Redó
Pharmaceuticals 2025, 18(8), 1107; https://doi.org/10.3390/ph18081107 - 25 Jul 2025
Viewed by 244
Abstract
Background/Objectives: Leishmaniasis is a zoonotic and anthropozoonotic disease with significant public health impact worldwide and is classified as a neglected tropical disease. The search for new affordable treatments, particularly oral and/or topical ones that are easy to administer and have fewer side [...] Read more.
Background/Objectives: Leishmaniasis is a zoonotic and anthropozoonotic disease with significant public health impact worldwide and is classified as a neglected tropical disease. The search for new affordable treatments, particularly oral and/or topical ones that are easy to administer and have fewer side effects, remains a priority for the scientific community in this field of research. In previous investigations, 3-alkoxy-1-benzyl-5-nitroindazole derivatives showed remarkable in vitro results against Leishmania species, and predictions of absorption, distribution, metabolism, excretion, and toxicity properties, as well as pharmacological scores, of the compounds classified as active were superior to those of amphotericin B, indicating their potential as candidates for in vivo studies. Therefore, the aim of the present study was to evaluate the in vivo antileishmanial activity of the indazole derivatives NV6 and NV16. Methods: The compounds were administered intralesionally at concentrations of 10 and 5 mg/kg in a BALB/c mouse model of cutaneous leishmaniasis caused by Leishmania amazonensis. To evaluate the efficacy of the compounds, indicators such as lesion size, ulcer area, lesion weight, and parasitic load were determined. Amphotericin B was used as a positive control. Results: The compound NV6 showed leishmanicidal activity comparable to that observed with amphotericin B, with a significant reduction in lesion development and parasite load, while NV16 caused a reduction in ulcer area. Conclusions: These results provide strong evidence for the antileishmanial activity of NV6 and support future studies to improve its pharmacokinetic profile, as well as the investigation of combination therapies with other chemotherapeutic agents currently in use. Full article
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54 pages, 1242 KiB  
Review
Optical Sensor-Based Approaches in Obesity Detection: A Literature Review of Gait Analysis, Pose Estimation, and Human Voxel Modeling
by Sabrine Dhaouadi, Mohamed Moncef Ben Khelifa, Ala Balti and Pascale Duché
Sensors 2025, 25(15), 4612; https://doi.org/10.3390/s25154612 - 25 Jul 2025
Viewed by 200
Abstract
Optical sensor technologies are reshaping obesity detection by enabling non-invasive, dynamic analysis of biomechanical and morphological biomarkers. This review synthesizes recent advances in three key areas: optical gait analysis, vision-based pose estimation, and depth-sensing voxel modeling. Gait analysis leverages optical sensor arrays and [...] Read more.
Optical sensor technologies are reshaping obesity detection by enabling non-invasive, dynamic analysis of biomechanical and morphological biomarkers. This review synthesizes recent advances in three key areas: optical gait analysis, vision-based pose estimation, and depth-sensing voxel modeling. Gait analysis leverages optical sensor arrays and video systems to identify obesity-specific deviations, such as reduced stride length and asymmetric movement patterns. Pose estimation algorithms—including markerless frameworks like OpenPose and MediaPipe—track kinematic patterns indicative of postural imbalance and altered locomotor control. Human voxel modeling reconstructs 3D body composition metrics, such as waist–hip ratio, through infrared-depth sensing, offering precise, contactless anthropometry. Despite their potential, challenges persist in sensor robustness under uncontrolled environments, algorithmic biases in diverse populations, and scalability for widespread deployment in existing health workflows. Emerging solutions such as federated learning and edge computing aim to address these limitations by enabling multimodal data harmonization and portable, real-time analytics. Future priorities involve standardizing validation protocols to ensure reproducibility, optimizing cost-efficacy for scalable deployment, and integrating optical systems with wearable technologies for holistic health monitoring. By shifting obesity diagnostics from static metrics to dynamic, multidimensional profiling, optical sensing paves the way for scalable public health interventions and personalized care strategies. Full article
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14 pages, 12586 KiB  
Article
Three-Dimensional Mineralization Prediction Using the Information Value Method: A Case Study of the Bainiuchang Ag Polymetallic Deposit, Southwest China
by Fuju Jia, Guolong Zheng, Guangzhi Meng, Long Jian, He Chang, Ping Pan, Jianguo Gao, Zhixiao Wu and Ceting Yang
Minerals 2025, 15(8), 783; https://doi.org/10.3390/min15080783 - 25 Jul 2025
Viewed by 192
Abstract
Three-dimensional geological modeling combined with the information value method offers a powerful approach for predicting mineralization in complex geological settings. This study applies these techniques to the Bainiuchang Ag polymetallic deposit in Southwest China. We constructed a detailed 3D geological model to identify [...] Read more.
Three-dimensional geological modeling combined with the information value method offers a powerful approach for predicting mineralization in complex geological settings. This study applies these techniques to the Bainiuchang Ag polymetallic deposit in Southwest China. We constructed a detailed 3D geological model to identify key geological factors influencing mineralization, such as the F3 fault, secondary faults, and the middle Cambrian Tianpeng Formation. Using the information value method, we evaluated the mineralization potential of each unit in the study area. Receiver operating characteristic (ROC) curves and fractal analysis were employed to determine an optimal threshold (information value > 2.6) for delineating high-potential exploration targets. Our results identified three priority targets (A1, A2, and A3), demonstrating the effectiveness of integrating 3D modeling with probabilistic mineral prospectivity mapping. This approach provides a robust framework for deep and peripheral exploration in structurally complex deposits, offering valuable insights for future mineral exploration efforts. Full article
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24 pages, 12938 KiB  
Article
Spatial Distribution of Mangrove Forest Carbon Stocks in Marismas Nacionales, Mexico: Contributions to Climate Change Adaptation and Mitigation
by Carlos Troche-Souza, Edgar Villeda-Chávez, Berenice Vázquez-Balderas, Samuel Velázquez-Salazar, Víctor Hugo Vázquez-Morán, Oscar Gerardo Rosas-Aceves and Francisco Flores-de-Santiago
Forests 2025, 16(8), 1224; https://doi.org/10.3390/f16081224 - 25 Jul 2025
Viewed by 575
Abstract
Mangrove forests are widely recognized for their effectiveness as carbon sinks and serve as critical ecosystems for mitigating the effects of climate change. Current research lacks comprehensive, large-scale carbon storage datasets for wetland ecosystems, particularly across Mexico and other understudied regions worldwide. Therefore, [...] Read more.
Mangrove forests are widely recognized for their effectiveness as carbon sinks and serve as critical ecosystems for mitigating the effects of climate change. Current research lacks comprehensive, large-scale carbon storage datasets for wetland ecosystems, particularly across Mexico and other understudied regions worldwide. Therefore, the objective of this study was to develop a high spatial resolution map of carbon stocks, encompassing both aboveground and belowground components, within the Marismas Nacionales system, which is the largest mangrove complex in northeastern Pacific Mexico. Our approach integrates primary field data collected during 2023–2024 and incorporates some historical plot measurements (2011–present) to enhance spatial coverage. These were combined with contemporary remote sensing data, including Sentinel-1, Sentinel-2, and LiDAR, analyzed using Random Forest algorithms. Our spatial models achieved strong predictive accuracy (R2 = 0.94–0.95), effectively resolving fine-scale variations driven by canopy structure, hydrologic regime, and spectral heterogeneity. The application of Local Indicators of Spatial Association (LISA) revealed the presence of carbon “hotspots,” which encompass 33% of the total area but contribute to 46% of the overall carbon stocks, amounting to 21.5 Tg C. Notably, elevated concentrations of carbon stocks are observed in the central regions, including the Agua Brava Lagoon and at the southern portion of the study area, where pristine mangrove stands thrive. Also, our analysis reveals that 74.6% of these carbon hotspots fall within existing protected areas, demonstrating relatively effective—though incomplete—conservation coverage across the Marismas Nacionales wetlands. We further identified important cold spots and ecotones that represent priority areas for rehabilitation and adaptive management. These findings establish a transferable framework for enhancing national carbon accounting while advancing nature-based solutions that support both climate mitigation and adaptation goals. Full article
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31 pages, 2271 KiB  
Article
Research on the Design of a Priority-Based Multi-Stage Emergency Material Scheduling System for Drone Coordination
by Shuoshuo Gong, Gang Chen and Zhiwei Yang
Drones 2025, 9(8), 524; https://doi.org/10.3390/drones9080524 - 25 Jul 2025
Viewed by 263
Abstract
Emergency material scheduling (EMS) is a core component of post-disaster emergency response, with its efficiency directly impacting rescue effectiveness and the satisfaction of affected populations. However, due to severe road damage, limited availability of resources, and logistical challenges after disasters, current EMS practices [...] Read more.
Emergency material scheduling (EMS) is a core component of post-disaster emergency response, with its efficiency directly impacting rescue effectiveness and the satisfaction of affected populations. However, due to severe road damage, limited availability of resources, and logistical challenges after disasters, current EMS practices often suffer from uneven resource distribution. To address these issues, this paper proposes a priority-based, multi-stage EMS approach with drone coordination. First, we construct a three-level EMS network “storage warehouses–transit centers–disaster areas” by integrating the advantages of large-scale transportation via trains and the flexible delivery capabilities of drones. Second, considering multiple constraints, such as the priority level of disaster areas, drone flight range, transport capacity, and inventory capacities at each node, we formulate a bilevel mixed-integer nonlinear programming model. Third, given the NP-hard nature of the problem, we design a hybrid algorithm—the Tabu Genetic Algorithm combined with Branch and Bound (TGA-BB), which integrates the global search capability of genetic algorithms, the precise solution mechanism of branch and bound, and the local search avoidance features of Tabu search. A stage-adjustment operator is also introduced to better adapt the algorithm to multi-stage scheduling requirements. Finally, we designed eight instances of varying scales to systematically evaluate the performance of the stage-adjustment operator and the Tabu search mechanism within TGA-BB. Comparative experiments were conducted against several traditional heuristic algorithms. The experimental results show that TGA-BB outperformed the other algorithms across all eight test cases, in terms of both average response time and average runtime. Specifically, in Instance 7, TGA-BB reduced the average response time by approximately 52.37% compared to TGA-Particle Swarm Optimization (TGA-PSO), and in Instance 2, it shortened the average runtime by about 97.95% compared to TGA-Simulated Annealing (TGA-SA).These results fully validate the superior solution accuracy and computational efficiency of TGA-BB in drone-coordinated, multi-stage EMS. Full article
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