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385 Results Found

  • Article
  • Open Access
13 Citations
5,069 Views
18 Pages

Schizophrenia-Like Behavioral Impairments in Mice with Suppressed Expression of Piccolo in the Medial Prefrontal Cortex

  • Atsumi Nitta,
  • Naotaka Izuo,
  • Kohei Hamatani,
  • Ryo Inagaki and ,
  • Yuka Kusui,
  • Kequan Fu,
  • Takashi Asano,
  • Youta Torii,
  • Chikako Habuchi and
  • Yoshiaki Miyamoto
  • + 9 authors+ 4 authors

26 June 2021

Piccolo, a presynaptic cytomatrix protein, plays a role in synaptic vesicle trafficking in the presynaptic active zone. Certain single-nucleotide polymorphisms of the Piccolo-encoding gene PCLO are reported to be associated with mental disorders. How...

(This article belongs to the Special Issue Psychoneurobiology Research and Personalized Treatment of Schizophrenia)
  • Article
  • Open Access
15 Citations
4,740 Views
15 Pages

Increasing number of metagenome sequencing studies have proposed a central metabolic role of still understudied Archaeal members in natural and artificial ecosystems. However, their role in hydrocarbon cycling, particularly in the anaerobic biodegrad...

(This article belongs to the Section Environmental Microbiology)
  • Article
  • Open Access
7 Citations
3,441 Views
16 Pages

21 March 2023

The COVID-19 pandemic has had a dramatic socio-economic impact on mankind; however, the COVID-19 lockdown brought a drastic reduction of anthropic impacts on the environment worldwide, including the marine–coastal system. This study is concentrated o...

(This article belongs to the Special Issue Numerical Methods for the Solution of Hydraulic Engineering Problems)
  • Article
  • Open Access
88 Citations
10,114 Views
13 Pages

PICCOLO White-Light and Narrow-Band Imaging Colonoscopic Dataset: A Performance Comparative of Models and Datasets

  • Luisa F. Sánchez-Peralta,
  • J. Blas Pagador,
  • Artzai Picón,
  • Ángel José Calderón and ,
  • Francisco Polo,
  • Nagore Andraka,
  • Roberto Bilbao,
  • Ben Glover,
  • Cristina L. Saratxaga and
  • Francisco M. Sánchez-Margallo
  • + 5 authors+ 0 author

28 November 2020

Colorectal cancer is one of the world leading death causes. Fortunately, an early diagnosis allows for effective treatment, increasing the survival rate. Deep learning techniques have shown their utility for increasing the adenoma detection rate at c...

(This article belongs to the Special Issue Deep Learning Applied to Image Processing)
  • Review
  • Open Access
27 Citations
10,240 Views
39 Pages

DPSIR Model Applied to the Remediation of Contaminated Sites. A Case Study: Mar Piccolo of Taranto

  • Claudia Labianca,
  • Sabino De Gisi,
  • Francesco Todaro and
  • Michele Notarnicola

23 July 2020

The study critically analyses the complex situation of the Mar Piccolo of Taranto (South of Italy), considered one of the most polluted marine ecosystems in Europe. In order to investigate possible cause–effect relationships, useful to plan app...

(This article belongs to the Section Chemical and Molecular Sciences)
  • Case Report
  • Open Access
9 Citations
3,927 Views
7 Pages

23 January 2019

There is an increasing interest in using hyperspectral data for phenotyping and crop management while overcoming the challenge of changing atmospheric conditions. The Piccolo dual field-of-view system collects up- and downwelling radiation nearly sim...

(This article belongs to the Special Issue Sensors in Agriculture 2018)
  • Article
  • Open Access
11 Citations
9,210 Views
17 Pages

The Footprints of the Wreckage of the Italian Royal Navy Battleship Leonardo Da Vinci on the Mar Piccolo Sea-Bottom (Taranto, Southern Italy)

  • Giovanni Scardino,
  • Francesco De Giosa,
  • Marco D’Onghia,
  • Pietro Demonte and ,
  • Paola Fago,
  • Gianluca Saccotelli,
  • Eliana Valenzano,
  • Massimo Moretti,
  • Raffaele Velardo and
  • Giuseppe Mastronuzzi
  • + 7 authors+ 2 authors

9 June 2020

Over the last two decades, the scientific interest for marine geophysical surveys has shown a huge increase, mostly for multidisciplinary applicability on different studies, from historical heritage to environmental remediation. One of the main resea...

  • Article
  • Open Access
16 Citations
3,397 Views
21 Pages

Enrichment of Aerobic and Anaerobic Hydrocarbon-Degrading Bacteria from Multicontaminated Marine Sediment in Mar Piccolo Site (Taranto, Italy)

  • Bruna Matturro,
  • Maria Letizia Di Franca,
  • Barbara Tonanzi,
  • Carolina Cruz Viggi and ,
  • Federico Aulenta,
  • Magda Di Leo,
  • Santina Giandomenico and
  • Simona Rossetti
  • + 3 authors+ 0 author

Marine sediments act as a sink for the accumulation of various organic contaminants such as polychlorobiphenyls (PCBs). These contaminants affect the composition and activity of microbial communities, particularly favoring those capable of thriving f...

(This article belongs to the Section Environmental Microbiology)
  • Article
  • Open Access
2 Citations
2,156 Views
20 Pages

17 November 2024

The Mar Piccolo is a transitional water system located in Taranto city (Southern Italy); it is a semi-enclosed basin affected by severe pollution issues due to the presence of various industrial, agricultural and other anthropic activities that requi...

  • Article
  • Open Access
560 Views
20 Pages

Exploring the Structure of Seaweed Assemblages Under the Pressure of Non-Indigenous Species (NIS) in the Transitional Water System Mar Piccolo of Taranto (Mediterranean Sea, Southern Italy)

  • Giuseppe Denti,
  • Antonella Petrocelli,
  • Ester Cecere,
  • Fernando Rubino and ,
  • Francesca P. De Luca and
  • Pasquale Ricci
  • + 1 author+ 0 author

11 June 2026

This study portrays macroalgal assemblage structure in the transitional water system Mar Piccolo of Taranto (eLTER site) from 2012 to 2023, assessing the impact of the establishment of non-indigenous species (NIS). Seasonal sampling at three sites ev...

(This article belongs to the Special Issue Effect of Biological Invasion on Aquatic Ecosystems)
  • Interesting Images
  • Open Access
2 Citations
2,300 Views
7 Pages

26 June 2024

The collection of photos during the systematic monitoring activities is useful to witness the ecological role of marine phanerogams as hosts for a rich variety of organisms in coastal and transitional waters. Cymodocea nodosa is present in the Tarant...

(This article belongs to the Collection Interesting Images from the Sea)
  • Article
  • Open Access
8 Citations
3,985 Views
28 Pages

Spatial Distribution of Trace Elements in Sub-Surficial Marine Sediments: New Insights from Bay I of the Mar Piccolo of Taranto (Southern Italy)

  • Antonella Marsico,
  • Angela Rizzo,
  • Domenico Capolongo,
  • Francesco De Giosa and ,
  • Antonella Di Leo,
  • Stefania Lisco,
  • Giuseppe Mastronuzzi,
  • Massimo Moretti,
  • Giovanni Scardino and
  • Giovanni Scicchitano
  • + 5 authors+ 0 author

17 October 2023

Contaminated marine and coastal sediments represent the main source of secondary pollution for the aquatic environment and marine fauna, affecting, directly and indirectly, ecosystems and human health. The assessment of the distribution of chemical p...

  • Case Report
  • Open Access
2,374 Views
11 Pages

18 June 2025

Background and Clinical Significance: The incidence of persistent ductus arteriosus (PDA) in preterm infants is the highest and depends on their birth weight (BW) and respiratory condition after birth. Previously, after the unsuccessful drug treatmen...

(This article belongs to the Section Cardiology/Cardiovascular Medicine)
  • Article
  • Open Access
2 Citations
2,478 Views
15 Pages

A simulation of phytoplankton dynamics in the coastal shellfish farming site of Mar Piccolo in Taranto (Ionian, Mediterranean Sea) is here reported. This simulation is an element of a greater ecological model produced taking into account the System A...

(This article belongs to the Section Marine Biology)
  • Article
  • Open Access
12 Citations
3,474 Views
25 Pages

16 December 2021

Resting stages represent the answer for species to the variability of environmental conditions. In confined marine habitats, variability of conditions is high, and bottoms host plankton resting stages in the so-called “marine cyst banks”....

(This article belongs to the Section Biodiversity and Functionality of Aquatic Ecosystems)
  • Article
  • Open Access
2 Citations
2,093 Views
13 Pages

PCLO Is Associated with Tumor Mutational Burden and Immunity in Patients with Oral Squamous Cell Carcinoma

  • Yuping Liu,
  • Ye Zhang,
  • Lijing Zhu,
  • Zheng Zhou and ,
  • Yajuan Cui,
  • Heyu Zhang and
  • Chuanxiang Zhou
  • + 2 authors+ 0 author

To determine predictive biomarkers for prognosis by analyzing the association between tumor mutational burden (TMB) and mutant genes in patients with oral squamous cell carcinoma (OSCC) and to validate PCLO as an OSCC predictive biomarker, OSCC genet...

(This article belongs to the Special Issue Oral Cancer: Prophylaxis, Etiopathogenesis and Treatment, 2nd Edition)
  • Article
  • Open Access
57 Citations
9,414 Views
19 Pages

Leaf and Canopy Level Detection of Fusarium Virguliforme (Sudden Death Syndrome) in Soybean

  • Ittai Herrmann,
  • Steven K. Vosberg,
  • Prabu Ravindran,
  • Aditya Singh and ,
  • Hao-Xun Chang,
  • Martin I. Chilvers,
  • Shawn P. Conley and
  • Philip A. Townsend
  • + 3 authors+ 0 author

9 March 2018

Pre-visual detection of crop disease is critical for food security. Field-based spectroscopic remote sensing offers a method to enable timely detection, but still requires appropriate instrumentation and testing. Soybean plants were spectrally measur...

(This article belongs to the Section Remote Sensing in Agriculture and Vegetation)
  • Article
  • Open Access
5 Citations
3,363 Views
28 Pages

Icing poses a serious threat to flight safety, and ice accretion simulations are essential for addressing aircraft icing problems. In ice accretion prediction, systematic research covering all icing conditions based on actual flight phases is lacking...

(This article belongs to the Section Aeronautics)
  • Feature Paper
  • Article
  • Open Access
5 Citations
4,717 Views
14 Pages

17 February 2024

The use of immobilized alcohol dehydrogenases (ADHs) offers numerous advantages, especially in the reaction conditions required by industrial applications. Looking for more efficient and cost-effective methods of ADH immobilization, in this study we...

(This article belongs to the Section Biocatalysis)
  • Article
  • Open Access
2,160 Views
15 Pages

17 November 2025

The management of fouling through exposure of mussels to air has become risky due to rising temperatures, as it can negatively impact product quality and farm productivity. Since the early 2000s, during air exposure, mussel farmers of the Mar Piccolo...

  • Article
  • Open Access
1 Citations
1,848 Views
18 Pages

This study aims to enhance natural heritage through detailed monitoring aimed at evaluating ongoing environmental dynamics and anthropic impacts on fragile coastal ecosystems, with particular attention to dune ecosystems and back-dune ponds in Southe...

  • Article
  • Open Access
35 Citations
8,101 Views
34 Pages

Machine Learning and IoT Trends for Intelligent Prediction of Aircraft Wing Anti-Icing System Temperature

  • E. S. Abdelghany,
  • Mohamed B. Farghaly,
  • Mishari Metab Almalki,
  • H. H. Sarhan and
  • Mohamed El-Sayed M. Essa

Airplane manufacturers are frequently faced with formidable challenges to improving both aircraft performance and customer safety. Ice accumulation on the wings of aircraft is one of the challenges, which could result in major accidents and a reducti...

(This article belongs to the Special Issue Machine Learning for Aeronautics)
  • Article
  • Open Access
15 Citations
5,307 Views
23 Pages

Towards Sustainable Management of Mussel Farming through High-Resolution Images and Open Source Software—The Taranto Case Study

  • Carmine Massarelli,
  • Ciro Galeone,
  • Ilaria Savino,
  • Claudia Campanale and
  • Vito Felice Uricchio

29 July 2021

This research activity, conducted in collaboration with the Aero-Naval Operations Department of the Guardia di Finanza of Bari as part of the Special Commissioner for urgent measures of reclamation, environmental improvements and redevelopment of Tar...

(This article belongs to the Special Issue Integrated Applications of Geo-Information in Environmental Monitoring)
  • Article
  • Open Access
1,079 Views
13 Pages

The Pierpaoli’s Herbarium MBMP: A Historical Window into Marine Biodiversity of the Ionian Sea

  • Antonella Petrocelli,
  • Ester Cecere,
  • Lucia Spada and
  • Loredana Papa

1 November 2025

Herbaria, originally books of medicinal plants, became collections of dried plants after 1500, later extending to seaweeds and supporting taxonomy and systematics. Digitalization has made herbaria accessible, and advances in DNA sequencing have trans...

  • Article
  • Open Access
11 Citations
4,322 Views
10 Pages

Settlement and Spreading of the Introduced Seaweed Caulacanthus okamurae (Rhodophyta) in the Mediterranean Sea

  • Antonella Petrocelli,
  • Marion A. Wolf,
  • Ester Cecere,
  • Katia Sciuto and
  • Adriano Sfriso

30 March 2020

In this study, we report the first finding of the non-indigenous seaweed Caulacanthus okamurae (Rhodophyta) in the Ionian and Adriatic Seas (Mediterranean). Specimens were identified through molecular analyses based on the plastid ribulose-1,5-bispho...

(This article belongs to the Special Issue Biodiversity of Macroalgae)
  • Article
  • Open Access
9 Citations
5,360 Views
27 Pages

A Comprehensive and Systematic Diagnostic Campaign for a New Acquisition of Contemporary Art—The Case of Natura Morta by Andreina Rosa (1924–2019) at the International Gallery of Modern Art Ca’ Pesaro, Venice

  • Anna Piccolo,
  • Emanuele Bonato,
  • Laura Falchi,
  • Paola Lucero-Gómez and ,
  • Elisabetta Barisoni,
  • Matteo Piccolo,
  • Eleonora Balliana,
  • Dafne Cimino and
  • Francesca Caterina Izzo
  • + 4 authors+ 0 author

16 November 2021

A multi-analytical approach has been employed to investigate the painting Natura Morta (1954–1955) by Andreina Rosa (1924–2019) to assess the state of conservation and to understand more about the painting materials and techniques of this artwork, wh...

(This article belongs to the Special Issue Study and Characterization of Paintings: Materials, Artistic Techniques, and Conservation)
  • Article
  • Open Access
7 Citations
2,768 Views
19 Pages

Valorization of Arbutus unedo L. Pomace: Exploring the Recovery of Bioactive Phenolic Compounds from Distillation By-Products

  • Ritamaria Di Lorenzo,
  • Maria Grazia Ferraro,
  • Ceferino Carrera,
  • Federica Iazzetti and ,
  • Nuria Chinchilla,
  • Maria Maisto,
  • María José Aliaño-González,
  • Vincenzo Piccolo,
  • Anabela Romano and
  • Sonia Laneri
  • + 11 authors+ 6 authors

27 February 2025

This study explores the potential of Arbutus unedo L. pomace, a by-product of the food industry, as a natural ingredient for skincare applications. In Portugal, A. unedo L. fruits are traditionally used to produce “Aguardente de Medronho”...

  • Article
  • Open Access
4 Citations
2,424 Views
22 Pages

Environmental Degradation in the Italian Mediterranean Coastal Lagoons Shown by Satellite Imagery

  • Viola Pagliani,
  • Elena Arnau-López,
  • Noelia Campillo-Tamarit,
  • Manuel Muñoz-Colmenares and ,
  • Juan Miguel Soria and
  • Juan Víctor Molner
  • + 1 author+ 0 author

12 December 2025

Coastal lagoons are recent geological formations, crucial biodiversity hot-spots, and fragile ecosystems which provide several ecosystem services. These areas are strongly affected by nutrient inputs, which can lead to eutrophication and algal blooms...

  • Review
  • Open Access
31 Citations
8,542 Views
20 Pages

Prevention and Harm Reduction Interventions for Adult Gambling at the Local Level: An Umbrella Review of Empirical Evidence

  • Veronica Velasco,
  • Paola Scattola,
  • Laura Gavazzeni,
  • Lara Marchesi and ,
  • Ioana Elena Nita and
  • Gilberto Giudici
  • + 1 author+ 0 author

Concerns about negative consequences of gambling diffusion are increasing. Prevention and harm reduction strategies play a crucial role in reducing gambling supply and harms. This study aims to conduct an umbrella review of the effectiveness of gambl...

(This article belongs to the Special Issue Underlying Mechanisms in Behavioral Addictions and Their Meaning for Prevention and Intervention Strategies)
  • Article
  • Open Access
20 Citations
5,028 Views
20 Pages

Marine Sediments from a Contaminated Site: Geotechnical Properties and Chemo-Mechanical Coupling Processes

  • Francesca Sollecito,
  • Claudia Vitone,
  • Daniela Miccoli,
  • Michael Plötze and ,
  • Alexander M. Puzrin and
  • Federica Cotecchia
  • + 1 author+ 0 author

The city of Taranto in the south of Italy is one of the areas declared as “at high risk of environmental crisis” by the Italian government because it represents one of the most complex industrial sites in Europe, located near urban areas...

(This article belongs to the Special Issue Marine Sediments and Marine Environments)
  • Article
  • Open Access
3 Citations
2,966 Views
12 Pages

Transforming Chronic Pain Care Through Telemedicine: An Italian Perspective

  • Francesco Amato,
  • Maria Carmela Monaco and
  • Silvia Ceniti

Chronic pain (CP) is a complex and debilitating condition that significantly impairs quality of life and imposes a high burden on healthcare systems. This study aims to evaluate the impact of telemedicine on chronic pain management in cancer survivor...

  • Review
  • Open Access
4 Citations
4,909 Views
12 Pages

Machine Learning Algorithms to Estimate Propensity Scores in Health Policy Evaluation: A Scoping Review

  • Luís Lourenço,
  • Luciano Weber,
  • Leandro Garcia,
  • Vinicius Ramos and
  • João Souza

(1) Background: Quasi-experimental design has been widely used in causal inference for health policy impact evaluation. However, due to the non-randomized treatment used, there is great potential for bias in the assessment of the results, which can b...

  • Article
  • Open Access
7 Citations
2,394 Views
32 Pages

Light-Modulated Circadian Synaptic Plasticity in the Somatosensory Cortex: Link to Locomotor Activity

  • Małgorzata Jasińska,
  • Ewa Jasek-Gajda,
  • Marek Ziaja,
  • Jan A. Litwin and ,
  • Grzegorz J. Lis and
  • Elżbieta Pyza
  • + 1 author+ 0 author

29 November 2024

The circadian clock controls various physiological processes, including synaptic function and neuronal activity, affecting the functioning of the entire organism. Light is an important external factor regulating the day–night cycle. This study...

(This article belongs to the Section Molecular Neurobiology)
  • Article
  • Open Access
40 Citations
6,780 Views
25 Pages

4 March 2020

Honey is a natural pure food produced by honeybees from the nectar of various plants, and its chemical composition includes carbohydrates, water, and some minor compounds, which are very important for honey quality and authentication. Most of honey&r...

(This article belongs to the Section Chemical and Molecular Sciences)
  • Article
  • Open Access
29 Citations
4,390 Views
9 Pages

Potential Functional Snacks: Date Fruit Bars Supplemented by Different Species of Lactobacillus spp.

  • Maria Maisto,
  • Giuseppe Annunziata,
  • Elisabetta Schiano,
  • Vincenzo Piccolo and ,
  • Fortuna Iannuzzo,
  • Rosaria Santangelo,
  • Roberto Ciampaglia,
  • Gian Carlo Tenore,
  • Ettore Novellino and
  • Paolo Grieco
  • + 5 authors+ 0 author

29 July 2021

The influence of the addition of four different potential probiotic strains, Lactiplantibacillus plantarum subsp. plantarum (L. plantarum), Lactobacillus delbruekii subsp. bulgaricus (L. bulgaricus), Lactobacillus acidophilus (L. acidophilus) and Lac...

(This article belongs to the Special Issue New Insights into Food Fermentation)
  • Article
  • Open Access
47 Citations
6,265 Views
17 Pages

Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy

  • Meghan L. Ruebel,
  • Stephanie P. Gilley,
  • Clark R. Sims,
  • Ying Zhong and ,
  • Donald Turner,
  • Sree V. Chintapalli,
  • Brian D. Piccolo,
  • Aline Andres and
  • Kartik Shankar
  • + 4 authors+ 0 author

21 September 2021

Maternal body composition, gestational weight gain (GWG) and diet quality influence offspring obesity risk. While the gut microbiome is thought to play a crucial role, it is understudied in pregnancy. Using a longitudinal pregnancy cohort, maternal a...

(This article belongs to the Section Nutrition and Obesity)
  • Review
  • Open Access
20 Citations
4,648 Views
16 Pages

Circulating Long Non-Coding RNAs as Novel Potential Biomarkers for Osteogenic Sarcoma

  • Sutpirat Moonmuang,
  • Parunya Chaiyawat,
  • Salinee Jantrapirom,
  • Dumnoensun Pruksakorn and
  • Luca Lo Piccolo

21 August 2021

Circulating cell-free nucleic acids recently became attractive targets to develop non-invasive diagnostic tools for cancer detection. Along with DNA and mRNAs, transcripts lacking coding potential (non-coding RNAs, ncRNAs) directly involved in the pr...

(This article belongs to the Special Issue Liquid Nucleic Acid-Based Biomarkers in Solid Tumors)
  • Article
  • Open Access
17 Citations
3,971 Views
23 Pages

Multivariate Modeling of Mechanical Properties for Hot Runner Molded Bioplastics and a Recycled Polypropylene Blend

  • David O. Kazmer,
  • Davide Masato,
  • Leonardo Piccolo,
  • Kyle Puleo and ,
  • Joshua Krantz,
  • Varun Venoor,
  • Austin Colon,
  • Justin Limkaichong,
  • Neil Dewar and
  • Cheryl Sayer
  • + 6 authors+ 1 author

20 July 2021

Four sustainable materials including a recycled polypropylene blend, polybutylene adipate terephthalate, and two grades of polylactic acid are compared to a reference isotactic polypropylene. Tensile specimens were produced using a two-cavity, hot ru...

  • Article
  • Open Access
17 Citations
5,205 Views
11 Pages

Prominent and Regressive Brain Developmental Disorders Associated with Nance-Horan Syndrome

  • Celeste Casto,
  • Valeria Dipasquale,
  • Ida Ceravolo,
  • Antonella Gambadauro and ,
  • Emanuela Aliberto,
  • Karol Galletta,
  • Francesca Granata,
  • Giorgia Ceravolo,
  • Emanuela Falzia and
  • Roberto Chimenz
  • + 17 authors+ 12 authors

29 August 2021

Nance-Horan syndrome (NHS) is a rare X-linked developmental disorder caused mainly by loss of function variants in the NHS gene. NHS is characterized by congenital cataracts, dental anomalies, and distinctive facial features, and a proportion of the...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Feature Paper
  • Article
  • Open Access
12 Citations
7,022 Views
19 Pages

Preliminary Assessment of Cooling Water Chemistry for Fusion Power Plants

  • Eugenio Lo Piccolo,
  • Raffaele Torella,
  • Nicholas Terranova,
  • Luigi Di Pace and ,
  • Claudia Gasparrini and
  • Mauro Dalla Palma
  • + 1 author+ 0 author

The determination of the water chemistry for cooling systems of nuclear fusion plants is under debate. It should be tailored for different types of fusion reactors: either experimental, e.g., ITER, JT-60SA, and DTT, or aimed at power generation, e.g....

  • Article
  • Open Access
11 Citations
2,939 Views
21 Pages

The Effect of Fibrous Reinforcement on the Polycondensation Degree of Slag-Based Alkali Activated Composites

  • Isabella Lancellotti,
  • Federica Piccolo,
  • Hoang Nguyen,
  • Mohammad Mastali and ,
  • Mohammad Alzeer,
  • Mirja Illikainen and
  • Cristina Leonelli
  • + 2 authors+ 0 author

10 August 2021

Alternative cementitious binders, based on industrial side streams, characterized by a low carbon footprint, are profitably proposed to partially replace Portland cement. Among these alternatives, alkali-activated materials have attracted attention a...

(This article belongs to the Special Issue Geopolymers - Design, Preparation, Applications)
  • Article
  • Open Access
4 Citations
6,023 Views
11 Pages

Directional Dark Matter Searches with CYGNO

  • Fernando Domingues Amaro,
  • Elisabetta Baracchini,
  • Luigi Benussi,
  • Stefano Bianco and ,
  • Cesidio Capoccia,
  • Michele Caponero,
  • Gianluca Cavoto,
  • André Cortez,
  • Igor Abritta Costa and
  • Samuele Torelli
  • + 41 authors+ 36 authors

6 July 2021

The CYGNO project aims at developing a high resolution Time Projection Chamber with optical readout for directional dark matter searches and solar neutrino spectroscopy. Peculiar CYGNO’s features are the 3D tracking capability provided by the combina...

(This article belongs to the Special Issue Selected Papers from "New Horizons in Time Projection Chambers")
  • Article
  • Open Access
1 Citations
3,320 Views
14 Pages

Effects of Autologous Bone Marrow Mesenchymal Stem Cells and Platelet-Rich Plasma on Bone Regeneration and Osseointegration of a Hydroxyapatite-Coated Titanium Implant

  • Francesca Salamanna,
  • Nicolandrea Del Piccolo,
  • Maria Sartori,
  • Gianluca Giavaresi and ,
  • Lucia Martini,
  • Giuseppe Di Sante,
  • Cesare Stagni,
  • Dante Dallari and
  • Milena Fini
  • + 4 authors+ 0 author

12 July 2021

Bone regeneration remains one of the major clinical needs in orthopedics, and advanced and alternative strategies involving bone substitutes, cells, and growth factors (GFs) are mandatory. The purpose of this study was to evaluate whether the associa...

(This article belongs to the Section Bioactive Coatings and Biointerfaces)
  • Review
  • Open Access
30 Citations
7,448 Views
31 Pages

Immune-Based Therapy in Triple-Negative Breast Cancer: From Molecular Biology to Clinical Practice

  • Francesca Carlino,
  • Anna Diana,
  • Antonio Piccolo,
  • Anna Ventriglia and ,
  • Vincenzo Bruno,
  • Irene De Santo,
  • Ortensio Letizia,
  • Ferdinando De Vita,
  • Bruno Daniele and
  • Michele Orditura
  • + 6 authors+ 1 author

23 April 2022

Triple-negative breast cancer (TNBC) has been considered for many years an orphan disease in terms of therapeutic options, with conventional chemotherapy (CT) still representing the mainstay of treatment in the majority of patients. Although breast c...

(This article belongs to the Special Issue Triple Negative Breast Cancer: From Biology to Treatment)
  • Review
  • Open Access
80 Citations
5,717 Views
33 Pages

Bioactivity and Development of Small Non-Platinum Metal-Based Chemotherapeutics

  • Maria Grazia Ferraro,
  • Marialuisa Piccolo,
  • Gabriella Misso,
  • Rita Santamaria and
  • Carlo Irace

Countless expectations converge in the multidisciplinary endeavour for the search and development of effective and safe drugs in fighting cancer. Although they still embody a minority of the pharmacological agents currently in clinical use, metal-bas...

(This article belongs to the Special Issue Beyond the Platinum in Metal-Based Cancer Therapy)
  • Article
  • Open Access
29 Citations
4,110 Views
18 Pages

Thinned Nectarines, an Agro-Food Waste with Antidiabetic Potential: HPLC-HESI-MS/MS Phenolic Characterization and In Vitro Evaluation of Their Beneficial Activities

  • Elisabetta Schiano,
  • Vincenzo Piccolo,
  • Ettore Novellino,
  • Maria Maisto and ,
  • Fortuna Iannuzzo,
  • Vincenzo Summa and
  • Gian Carlo Tenore
  • + 2 authors+ 0 author

30 March 2022

Due to the side effects of synthetic drugs, the interest in the beneficial role of natural products in the management of diabetic conditions is growing over time. In the context of agro-food waste products, a screening of different fruit thinning by-...

(This article belongs to the Section Plant Foods)
  • Article
  • Open Access
7 Citations
11,193 Views
11 Pages

Sexual Desire and Body Image. Gender Differences and Correlations before and during COVID-19 Lockdown

  • Clemente Cedro,
  • Carmela Mento,
  • Maria Cristina Piccolo,
  • Fiammetta Iannuzzo and ,
  • Amelia Rizzo,
  • Maria Rosaria Anna Muscatello and
  • Gianluca Pandolfo
  • + 2 authors+ 0 author

Recent literature has extensively examined sexual behavior during lockdown due to COVID-19. However, there are no recent studies that have considered the relationship between body image quality, sexual arousability, and sexual anxiety. The present st...

(This article belongs to the Special Issue Women's Mental Health: A Framework for Its Assessment, Prevention, and Promotion in Health Care Settings)
  • Article
  • Open Access
8 Citations
4,842 Views
17 Pages

Effects of Dietary Supplementation with Honeybee Pollen and Its Supercritical Fluid Extract on Immune Response and Fillet’s Quality of Farmed Gilthead Seabream (Sparus aurata)

  • Rosaria Arena,
  • Adja Cristina Lira de Medeiros,
  • Giulia Secci,
  • Simone Mancini and ,
  • Simona Manuguerra,
  • Fulvia Bovera,
  • Andrea Santulli,
  • Giuliana Parisi,
  • Concetta Maria Messina and
  • Giovanni Piccolo
  • + 5 authors+ 0 author

8 March 2022

The awareness of the correlation between administered diet, fish health and products’ quality has led to the increase in the research for innovative and functional feed ingredients. Herein, a plant-derived product rich in bioactive compounds, s...

(This article belongs to the Collection Feeding Strategies to Improve Sustainability and Welfare in Animal Production)
  • Article
  • Open Access
40 Citations
5,760 Views
19 Pages

Alkali Activation of Metallurgical Slags: Reactivity, Chemical Behavior, and Environmental Assessment

  • Isabella Lancellotti,
  • Federica Piccolo,
  • Katja Traven,
  • Mark Češnovar and ,
  • Vilma Ducman and
  • Cristina Leonelli
  • + 1 author+ 0 author

30 January 2021

Alkali-activated materials (AAMs) represent a promising alternative to conventional building materials and ceramics. Being produced in large amounts as aluminosilicate-rich secondary products, such as slags, they can be utilized for the formulation o...

(This article belongs to the Special Issue Environmentally Sustainable Materials and Fabrication Techniques)
  • Article
  • Open Access
9 Citations
3,336 Views
10 Pages

Detection of SARS-CoV-2 and Other Infectious Agents in Lower Respiratory Tract Samples Belonging to Patients Admitted to Intensive Care Units of a Tertiary-Care Hospital, Located in an Epidemic Area, during the Italian Lockdown

  • Adriana Calderaro,
  • Mirko Buttrini,
  • Sara Montecchini,
  • Giovanna Piccolo and ,
  • Monica Martinelli,
  • Maria Loretana Dell'Anna,
  • Alan Di Maio,
  • Maria Cristina Arcangeletti,
  • Clara Maccari and
  • Carlo Chezzi
  • + 6 authors+ 1 author

The aim of this study was the detection of infectious agents from lower respiratory tract (LRT) samples in order to describe their distribution in patients with severe acute respiratory failure and hospitalized in intensive care units (ICU) in an Ita...

(This article belongs to the Special Issue COVID-19: Focusing on Epidemiologic, Virologic, and Clinical Studies)

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