Search Results (2,887)

This study investigates the thermal stability and microstructural evolution of the solid electrolyte medium used in DLyte^® dry electropolishing and dry anodizing processes. Samples were thermally aged between 30 °C and 45 °C to simulate Joule heating during industrial operation. Visual and SEM analyses revealed shape deformation and microcrack formation at temperatures above 40 °C, potentially reducing particle packing efficiency and electrolyte performance. Particle size distribution shifted from bimodal to trimodal upon aging, with an overall size reduction of up to 39.5% due to dehydration effects, impacting ionic transport properties. Weight-loss measurements indicated a diffusion-limited dehydration mechanism, stabilizing at 15–16% mass loss. Fourier transform infrared analysis confirmed water removal while maintaining the essential sulfonic acid groups responsible for ionic conductivity. In dry anodizing tests on titanium, aged electrolytes enhanced process efficiency, producing TiO₂ films with improved optical properties—color and brightness—while preserving thickness and uniformity (~70 nm). The results highlight the need to carefully control thermal exposure to maintain electrolyte integrity and ensure consistent process performance. Full article

With the rapid development of renewable energy, the proportion of small hydropower as a clean energy in the distribution network (DN) is increasing. However, the randomness and intermittence of small hydropower has brought new challenges to the operation of DN; especially, the problems of increasing network loss and reactive voltage exceeding the limit have become increasingly prominent. Aiming at the above problems, this paper proposes a reactive power optimization control method for DN with hydropower based on an improved discrete particle swarm optimization (PSO) algorithm. Firstly, this paper analyzes the specific characteristics of small hydropower and establishes its mathematical model. Secondly, considering the constraints of bus voltage and generator RP output, an extended minimum objective function for system power loss is established, with bus voltage violation serving as the penalty function. Then, in order to solve the following problems: that the traditional discrete PSO algorithm is easy to fall into local optimization and slow convergence, this paper proposes an improved discrete PSO algorithm, which improves the global search ability and convergence speed by introducing adaptive inertia weight. Finally, based on the IEEE-33 buses distribution system as an example, the simulation analysis shows that compared with GA optimization, the line loss can be reduced by 3.4% in the wet season and 13.6% in the dry season. Therefore, the proposed method can effectively reduce the network loss and improve the voltage quality, which verifies the effectiveness and superiority of the proposed method. Full article

In the 6G era, the proliferation of smart devices has led to explosive growth in data volume. The traditional cloud computing can no longer meet the demand for efficient processing of large amounts of data. Edge computing can solve the energy loss problems caused by transmission delay and multi-level forwarding in cloud computing by processing data close to the data source. In this paper, we propose a cloud–edge–end collaborative task offloading strategy with task response time and execution energy consumption as the optimization targets under a limited resource environment. The tasks generated by smart devices can be processed using three kinds of computing nodes, including user devices, edge servers, and cloud servers. The computing nodes are constrained by bandwidth and computing resources. For the target optimization problem, a genetic particle swarm optimization algorithm considering three layers of computing nodes is designed. The task offloading optimization is performed by introducing (1) opposition-based learning algorithm, (2) adaptive inertia weights, and (3) adjustive acceleration coefficients. All metaheuristic algorithms adopt a symmetric training method to ensure fairness and consistency in evaluation. Through experimental simulation, compared with the classic evolutionary algorithm, our algorithm reduces the objective function value by about 6–12% and has higher algorithm convergence speed, accuracy, and stability. Full article

Carbon fiber (CF) and carbon fiber-reinforced polymers (CFRPs) are widely used in the aerospace, automotive, and energy sectors due to their high strength, stiffness, and low density. However, significant waste is generated during manufacturing and after the use of CFRPs. Traditional disposal methods like landfilling and incineration are unsustainable. CFRP machining processes, such as drilling and milling, produce fine chips and dust that are difficult to recycle due to their heterogeneity and contamination. This study investigates the oxidation behavior of CFRP drilling waste from two types of materials (tube and plate) under oxidative (non-inert) conditions. Thermogravimetric analysis (TGA) was performed from 200 °C to 800 °C to assess weight loss related to polymer degradation and carbon fiber integrity. Scanning electron microscopy (SEM) was used to analyze morphological changes and fiber damage. The optimal range for removing the polymer matrix without significant fiber degradation has been identified as 500–600 °C. At temperatures above 700 °C, notable surface and internal fiber damage occurred, along with nanostructure formation, which may pose health and environmental risks. The results show that partial fiber recovery is possible under ambient conditions, and this must be considered regarding the harmful risks to the human body if submicron particles are inhaled. This research supports sustainable CFRP recycling and fire hazard mitigation. Full article

Background: Rock–blast design is a canonical inverse problem that joins elastodynamic partial differential equations (PDEs), fracture mechanics, and stochastic heterogeneity. Objective: Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, a systematic review of mathematical methods for geomechanically informed blast modelling and optimisation is provided. Methods: A Scopus–Web of Science search (2000–2025) retrieved 2415 records; semantic filtering and expert screening reduced the corpus to 97 studies. Topic modelling with Bidirectional Encoder Representations from Transformers Topic (BERTOPIC) and bibliometrics organised them into (i) finite-element and finite–discrete element simulations, including arbitrary Lagrangian–Eulerian (ALE) formulations; (ii) geomechanics-enhanced empirical laws; and (iii) machine-learning surrogates and multi-objective optimisers. Results: High-fidelity simulations delimit blast-induced damage with ≤0.2 m mean absolute error; extensions of the Kuznetsov–Ram equation cut median-size mean absolute percentage error (MAPE) from 27% to 15%; Gaussian-process and ensemble learners reach a coefficient of determination ($R^2>0.95$) while providing closed-form uncertainty; Pareto optimisers lower peak particle velocity (PPV) by up to 48% without productivity loss. Synthesis: Four themes emerge—surrogate-assisted PDE-constrained optimisation, probabilistic domain adaptation, Bayesian model fusion for digital-twin updating, and entropy-based energy metrics. Conclusions: Persisting challenges in scalable uncertainty quantification, coupled discrete–continuous fracture solvers, and rigorous fusion of physics-informed and data-driven models position blast design as a fertile test bed for advances in applied mathematics, numerical analysis, and machine-learning theory. Full article

This study investigates the impact of partially replacing cement with fly ash (FA) on the mechanical performance of fiber-reinforced rubberized concrete (FRRC) incorporating waste tyre rubber and recycled macro-synthetic fibers (MSF). FRRC mixtures were prepared with varying fly ash replacement levels (0%, 25%, and 50%), rubber aggregate contents (0%, 10%, and 20% by volume of fine aggregate), and macro-synthetic fiber dosages (0% to 1% by total volume). The fresh properties were evaluated through slump tests, while hardened properties including compressive strength, splitting tensile strength, and flexural strength were systematically assessed. Results demonstrated that fly ash substitution up to 25% improved the interfacial bonding between rubber particles, fibers, and the cementitious matrix, leading to enhanced tensile and flexural performance without significantly compromising compressive strength. However, at 50% replacement, strength reductions were more pronounced due to slower pozzolanic reactions and reduced cement content. The inclusion of MSF effectively mitigated strength loss induced by rubber aggregates, improving post-cracking behavior and toughness. Overall, an optimal balance was achieved at 25% fly ash replacement combined with 10% rubber and 0.5% fiber content, producing a more sustainable composite with favorable mechanical properties while reducing carbon and ecological footprints. These findings highlight the potential of integrating industrial by-products and waste materials to develop eco-friendly, high-performance FRRC for structural applications, supporting circular economy principles and reducing the carbon footprint of concrete infrastructure. Full article

Background/Objectives: Porcine circovirus type 2 (PCV2) infection causes porcine circovirus disease (PCVD), a global immunosuppressive disease in pigs. Its clinical manifestations include post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS), which cause significant economic losses to the swine industry. The Cap protein, which is the major protective antigen of PCV2, can self-assemble to form virus-like particles (VLPs) in the insect baculovirus expression system. Few studies have compared the expression of Cap proteins in different baculovirus expression systems. Methods: In this study, we compared two commonly commercialized baculovirus construction systems with the Cap protein expression in various insect cells. Results: The results demonstrate that the flashBAC system expressed the Cap protein at higher levels than the Bac-to-Bac system. Notably, when expressing four copies of the Cap protein, the flashBAC system achieved the highest protein yield in High Five cells, where it reached 432 μg/mL at 5 days post-infection (dpi) with 27 °C cultivation. Animal experiments confirmed that the purified Cap protein effectively induced specific antibody production in mice and swine. Conclusions: This study provides critical data for optimizing the production of the PCV2 Cap protein, which is of great significance for reducing the production cost of PCV2 vaccines and improving the industrial production efficiency. Full article

An anion exchange-assisted technique was used for the synthesis of platinum-decorated SnO₂ supports, providing nanocatalysts with enhanced activity for the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP). In this study, a series of SnO₂ supports, namely SnA (synthesized almost at room temperature), SnB (hydrothermally treated at 180 °C), and SnC (annealed at 600 °C), are systematically investigated, all loaded with 1 mol% Pt from H₂PtCl₆ under identical mild conditions. The chloride ions from the SnCl₄ precursors were efficiently removed via a strong-base anion exchange reaction, resulting in highly dispersed, crystalline ~5 nm cassiterite SnO₂ particles. All Pt/SnO₂ composites displayed mesoporous structures with type IVa isotherms and H₂-type hysteresis, with SP1a (Pt on SnA) exhibiting the largest surface area (122.6 m²/g) and the smallest pores (~3.5 nm). STEM-HAADF imaging revealed well-dispersed PtOx domains (~0.85 nm), while XPS confirmed the dominant Pt⁴⁺ and Pt²⁺ species, with ~25% Pt⁰ likely resulting from photoreduction and/or interactions with Sn–OH surface groups. Raman spectroscopy revealed three new bands (260–360 cm⁻¹) that were clearly visible in the sample with 10 mol% Pt and were due to the vibrational modes of the PtOx species and Pt-Cl bonds introduced due the addition and hydrolysis of H₂PtCl₆ precursor. TGA/DSC analysis revealed the highest mass loss for SP1a (~7.3%), confirming the strong hydration of the PtOx domains. Despite the predominance of oxidized PtOx species, SP1a exhibited the highest catalytic activity (k_app = 1.27 × 10⁻² s⁻¹) and retained 84.5% activity for the reduction of 4-NP to 4-AP after 10 cycles. This chloride-free low-temperature synthesis route offers a promising and generalizable strategy for the preparation of noble metal-based nanocatalysts on oxide supports with high catalytic activity and reusability. Full article

Channeling in cementing causes interlayer interference, severely restricting oilfield recovery. Existing channeling plugging agents, such as cement and gels, often lead to reservoir damage or insufficient strength. Oil-soluble resin (OSR) particles show great potential in selective plugging of channeling fractures due to their excellent oil solubility, temperature/salt resistance, and high strength. However, their application is limited by the efficient filling and retention in deep fractures. This study innovatively combines the OSR particle plugging system with the mature rapid filtration loss plugging mechanism in drilling, systematically exploring the influence of particle size and sorting on their filtration, packing behavior, and plugging performance in channeling fractures. Through API filtration tests, visual fracture models, and high-temperature/high-pressure (100 °C, salinity 3.0 × 10⁵ mg/L) core flow experiments, it was found that well-sorted large particles preferentially bridge in fractures to form a high-porosity filter cake, enabling rapid water filtration from the resin plugging agent. This promotes efficient accumulation of OSR particles to form a long filter cake slug with a water content <20% while minimizing the invasion of fine particles into matrix pores. The slug thermally coalesces and solidifies into an integral body at reservoir temperature, achieving a plugging strength of 5–6 MPa for fractures. In contrast, poorly sorted particles or undersized particles form filter cakes with low porosity, resulting in slow water filtration, high water content (>50%) in the filter cake, insufficient fracture filling, and significantly reduced plugging strength (<1 MPa). Finally, a double-slug strategy is adopted: small-sized OSR for temporary plugging of the oil layer injection face combined with well-sorted large-sized OSR for main plugging of channeling fractures. This strategy achieves fluid diversion under low injection pressure (0.9 MPa), effectively protects reservoir permeability (recovery rate > 95% after backflow), and establishes high-strength selective plugging. This study clarifies the core role of particle size and sorting in regulating the OSR plugging effect based on rapid filtration loss, providing key insights for developing low-damage, high-performance channeling plugging agents and scientific gradation of particle-based plugging agents. Full article

The accelerated hydrolytic degradation of poly(L-lactide) (PLA)/magnesium (Mg) composite films was investigated to elucidate the influence of surface modification of Mg particles on the degradation behavior and characteristics of PLA composites. Accelerated degradation studies were conducted at 60 °C in a pH 7.4 phosphate-buffered solution over 7 weeks, with degradation monitored using several techniques: mass loss, water absorption, thermal analysis, and Raman spectroscopy. The results indicated that all composite films experienced more than 90% mass loss at the end of experiment; however, PLA/5MgTT and PLA/5MgPEI exhibited the highest resistance to degradation, likely due to the protective effect of the surface modification induced by thermal treatment and polyethylenimine (PEI). Notably, these characteristics did not compromise the biocompatibility or osteogenic potential of the films, which remained comparable to the control samples when tested on human bone marrow multipotent mesenchymal/stromal cells. Full article

Background/Objectives: Parenteral nutrition (PN) supports patients unable to receive nutrients via the gastrointestinal tract, but it lacks the health-promoting natural bioactive compounds found in a typical oral diet. This study aimed to develop a human serum albumin-based intravenous delivery system for lutein (an antioxidant carotenoid with vision-supportive and hepatoprotective properties) as a PN additive. Methods: An albumin–lutein nanosuspension (AlbLuteN) was synthesized using a modified nanoparticle albumin-bound (nab^TM) technology and characterized physicochemically. The nanoformulation was added to four commercial PN admixtures to assess the supplementation safety throughout the maximum infusion period. Visual inspection and measurements of fat globules larger than 5 µm (PFAT5) and the mean hydrodynamic diameter (Z-average), zeta potential, pH, osmolality, and lutein content were performed to detect potential interactions and evaluate the physicochemical stability. Results: AlbLuteN consisted of uniform particles (Z-average of 133.5 ± 2.8 nm) with a zeta potential of −28.1 ± 1.8 mV, lutein content of 4.76 ± 0.39%, and entrapment efficiency of 84.4 ± 6.3%. Differential scanning calorimetry confirmed the amorphous state of lutein in the nanosuspension. AlbLuteN was successfully incorporated into PN admixtures, without visible phase separation or significant changes in physicochemical parameters. The PFAT5 and Z-average values remained within pharmacopeial limits over 24 h. No substantial shifts in zeta potential, pH, or osmolality were observed. The lutein content remained stable, with losses below 3%. Conclusions: AlbLuteN can be safely added to representative PN admixtures without compromising their stability. This approach offers a novel strategy for intravenous lutein delivery and may contribute to improving the nutritional profile of PN. Full article

Although PLA is an attractive biodegradable polymer, its degradation under natural conditions is often slow. This study investigates whether incorporating pounamu (New Zealand jade) particles into PLA can enhance its biodegradation rate under composting conditions at room temperature. PLA composites containing 0 to 15 wt% pounamu were fabricated using both compression molding and 3D printing. A simple, reproducible protocol based on residual mass measurement was developed to monitor the biodegradation process over a 12-month period. The results showed that increasing pounamu content consistently accelerated mass loss of the composite in the compost, indicating enhanced biodegradation. The 3D-printed samples degraded more rapidly than compression-molded ones. This was attributed to the layered structure, internal microcavities, and lower crystallinity of the 3D-printed samples, which provided greater surface area and accessibility for microbial activity. These findings highlight the dual role of pounamu as both a crystallization promoter and a facilitator of biodegradation and underscore the importance of the processing method when designing biodegradable polymer composites for real-world applications. Full article

Machine learning models that only use data for training and forecasting oilfield production have a sense of disconnection from the physical background, while embedding development patterns in them can enhance interpretability and even improve accuracy. In this paper, a novel multi-well production forecasting model embedded with decline curve analysis (DCA) is proposed, enabling the machine learning model to incorporate physical information. Moreover, an improved particle swarm optimization algorithm is proposed to optimize the hyperparameters in the loss function of the model. These hyperparameters determine the importance of the overall DCA and each module in training, which traditionally requires expert knowledge to determine. Simulation results based on the benchmark reservoir model show that the model has better forecasting ability and generalization performance compared to typical machine learning methods. Full article

Background/Objectives: Paclitaxel (PTX) is widely used in the treatment of a variety of solid tumours due to its broad-spectrum anti-tumour activity, but its use in brain gliomas is limited by insufficient blood–brain tumour barrier (BBTB) penetration and systemic toxicity. The aim of this study was to develop a Solutol HS-15-based micellar nanoparticle (PSM) to enhance the brain glioma targeting of PTX and reduce toxicity. Methods: PSMs were prepared by solvent injection and characterised for particle size, encapsulation rate, haemolysis rate and in vitro release properties. A C6 in situ glioma mouse model was used to assess the brain targeting and anti-tumour effects of the PSM by in vivo imaging, tissue homogenate fluorescence analysis and bioluminescence monitoring. Meanwhile, its safety was evaluated by weight monitoring, serum biochemical indexes and histopathological analysis. Results: The particle size of PSMs was 13.45 ± 0.70 nm, with an encapsulation rate of 96.39%, and it demonstrated excellent cellular uptake. In tumour-bearing mice, PSMs significantly enhanced brain tumour targeting with a brain drug concentration 5.94 times higher than that of free PTX. Compared with Taxol, PSMs significantly inhibited tumour growth (terminal luminescence intensity <1 × 10⁶ p/s/cm²/Sr) and did not cause significant liver or kidney toxicity or body weight loss. Conclusions: PSMs achieve an efficient accumulation of brain gliomas through passive targeting and EPR effects while significantly reducing the systemic toxicity of PTX. Its simple preparation process and excellent therapeutic efficacy support its use as a potential clinically translational candidate for glioma treatment. Full article

The griffon vulture (Gyps fulvus fulvus) is a scavenger species that plays a vital ecological role in carrion removal. Successful survival and reproduction in captive and wildlife conditions require optimal physical status and plumage integrity. Nutritional and environmental factors, systemic diseases, and various etiological agents can influence feather alterations. Although frequently documented in captive psittacine species, feather abnormalities are extremely rare in wild birds. Since 2020, two free-living griffon vultures in northeastern Italy have been found in poor physical condition, unable to fly due to partial feather loss and malformation of remiges and rectrices. Histopathologic examination of follicles and peri-follicular tissue revealed atrophy, keratin replacement, vasculitis, and calamus dystrophy with lymphohistiocytic perivasculitis. Immunohistochemical and ultrastructural analysis identified the presence of virus-like particles in epithelial and inflammatory cells. Although virome analysis did not confirm the presence of this virus in pooled affected samples, this study provides the first report of an emerging plumage disorder in free-ranging griffon vultures, which requires further characterization. Full article