Search Results (274)

Rapid vaccine availability is essential for effective epidemic and pandemic response. Building on the Coalition for Epidemic Preparedness Innovations (CEPI) 100 Days Mission, which aims to have new vaccines ready for initial authorization and manufacturing at scale within 100 days of recognition of a pandemic pathogen, the CEPI has developed a Chemistry, Manufacturing and Controls (CMC) Rapid Response Framework to define technical and logistical CMC requirements to enable rapid vaccine availability. Central to this framework is the availability of adaptable vaccine platforms that can be readily tailored to emerging pathogens. To support strategic decision-making and identify gaps in platform capabilities, CEPI has created the Platform Readiness Dashboard. This tool provides a structured, multi-dimensional initial assessment of platform maturity across six key categories: Adaptability, Compatibility, Suitability, Regulatory, Manufacturing, and Facility Readiness. Each category includes specific technical and operational considerations scored using a color-coded system to reflect outbreak response readiness level. This Dashboard aims to enable vaccine developers, manufacturers, funders, and outbreak response teams to evaluate platform strengths and limitations at any given time, informing funding, preparedness and response activities. By offering a dynamic view of essential platform readiness indicators, the dashboard can communicate progress supporting faster responses to future health emergencies. Full article

Introduction: This prospective descriptive study explored the disparities in perceptions and experiences regarding healthcare services between providers and users during the COVID-19 pandemic, with a specific focus on the impact of the digital divide on access to and quality of care. The study revealed significant inconsistencies in the experiences of healthcare providers and patients, particularly regarding the effectiveness of digital health interventions. Methods: This study was a prospective descriptive analysis conducted to evaluate and compare the use of electronic healthcare services between healthcare employees (HΕs) (N = 290) and consumers (Cs) (N = 263) from December 2024 to May 2025, utilizing an electronic survey after the COVID-19 pandemic. To ensure the statistical validity of the sample size, a power analysis was performed using G*Power 3.1.9.2 software. A questionnaire was developed to evaluate the readiness of healthcare employees and consumers for electronic healthcare services. It was validated to ensure reliability within this population and comprised 49 questions. Results: The response rate of the participants was 89.19%, and the Cronbach’s alpha for the questionnaire was 0.738. The study revealed notable differences in perceptions regarding health-related information and digital health technologies across genders and age groups. Specifically, 28.8% of females and 27.3% of males considered it important to be well-informed about health issues (χ² = 8.83, df = 3, p = 0.032). Conclusions: This research contributes to filling a gap in comparative analyses of provider and user perspectives, offering a comprehensive view of how digital health was adopted and experienced during a global crisis. Practically, it provides an evidence base to guide future interventions aimed at fostering more equitable, resilient, and user-friendly digital healthcare systems. Full article

The COVID-19 pandemic revealed long-standing vulnerabilities in island tourism economies such as Crete and Chios, including seasonality, overdependence on mass tourism, and limited innovation adoption. This study investigates how sustainable tourism, regional development, and innovation interconnect in these two cases. Drawing on structured questionnaires addressed to tourism stakeholders in Hersonissos (Crete) and Chios, we apply a comparative analysis through descriptive and inferential statistics. The findings reveal a common interest in diversifying tourism offerings through digital transformation and alternative tourism models. Hersonissos demonstrates higher engagement with innovation-led strategies, while Chios reflects a cautious but growing inclination toward eco-tourism and cultural tourism initiatives. The study employs a comparative cross-sectional design based on structured questionnaires addressed to 71 tourism stakeholders in Hersonissos and Chios. Data were collected through purposive sampling that was completed in July 2023. As a practical outcome, we propose the Regional Innovation Index in Tourism—a composite tool designed to assess innovation readiness at the local level. This index enables policymakers to evaluate the strategic capacity of tourism regions and supports the formulation of long-term, place-based development strategies aligned with EU policy goals and the transition to a green economy. Full article

The H5N1 avian influenza virus continues to evolve into genetically diverse and highly pathogenic clades with increased potential for cross-species transmission. Recent scientific advances have included the development of next-generation vaccine platforms, promising antiviral compounds, and more sensitive diagnostic tools, alongside strengthened surveillance systems in both animals and humans. However, persistent structural challenges hinder global readiness. Vaccine production is heavily concentrated in high-income countries, limiting equitable access during potential pandemics. Economic and logistical barriers complicate the implementation of control strategies such as vaccination, culling, and compensation schemes. Gaps in international coordination, public communication, and standardization of protocols further exacerbate vulnerabilities. Although sustained human-to-human transmission has not been documented, the severity of confirmed infections and the rapid global spread among wildlife and domestic animals underscore the urgent need for robust preparedness. International organizations have called for comprehensive pandemic response plans, enhanced multisectoral collaboration, and investment in targeted research. Priorities include expanding surveillance to asymptomatic animal hosts, evaluating viral shedding and transmission routes, and developing strain-specific and universal vaccines. Strengthening global cooperation and public health infrastructure will be critical to mitigate the growing threat of H5N1 and reduce the risk of a future influenza pandemic. Full article

Urban logistics are facing growing sustainability challenges, particularly in last-mile delivery operations, which contribute significantly to traffic congestion, emissions and operational inefficiencies. The COVID-19 pandemic further exposed the vulnerabilities in traditional logistics systems, accelerating interest in innovative solutions such as electric vehicles (EVs) and autonomous vehicles (AVs) for last-mile delivery. This study investigates the potential of EV and AV technologies to enhance sustainable urban logistics by integrating cleaner, smarter transportation into delivery networks. Drawing on survey data from logistics professionals and consumers in Italy, the findings highlight the key benefits of EV and AV adoption, including reduced emissions, improved delivery efficiency and increased resilience during global disruptions. Autonomous delivery robots and EV fleets can reduce labor costs, traffic congestion and carbon footprints while meeting evolving consumer demands. However, barriers such as limited charging infrastructure, range constraints, and technological readiness remain critical challenges. By addressing these issues and aligning EV and AV strategies with urban mobility policies, last-mile delivery systems can play a crucial role in advancing cleaner, more efficient and sustainable urban logistics. This research emphasizes the need for continued investment, policy support and public–private collaboration to fully realize the potential of EVs and AVs in reshaping future urban delivery systems. Full article

Background/Objectives: The COVID-19 pandemic has significantly restricted clinical training for midwifery students, highlighting the need for alternative teaching methods. With the disruption of traditional face-to-face education, online simulation-based training has emerged as an effective alternative for developing essential clinical skills. The acquisition of hands-on skills has a direct impact on students’ self-confidence and clinical performance. Interactive online simulations support the learning process by enhancing both theoretical knowledge and practical competencies. This study aims to evaluate the impact of online simple simulation-based episiotomy repair training on students whose clinical practice was limited due to the COVID-19 pandemic. Methods: A mixed-method approach was used, considering the outcomes from 61 midwifery students. Data were collected via observational questionnaires, which provide an online learning readiness scale and scales for student satisfaction and self-confidence. The analysis included descriptive statistics, McNemar’s, binary logistic regression, and the Mann–Whitney U test. Results: Students who trusted themselves in both opening and repairing an episiotomy after training had more readiness for online learning (t(43) = 2.73, p = 0.009; t(43) = 2.40, p = 0.02). Students with better training performance are more likely to obtain higher scores on the final exam of the Clinical Practice module (rho = 0.33, p = 0.01). Additionally, their performance was a positive and significant predictor of achieving a full mark (b = 0.11, s.e. = 0.05, p = 0.01). Conclusions: Interactive online simulation training improved midwifery students’ hand skills and self-confidence in clinical practice. Such methods should be promoted in circumstances like COVID-19. Full article

This research analyzes the digital readiness of Latin American countries by assessing the following key factors: digital infrastructure, human capital, internet use, adoption of digital technology by businesses, and digital government services. These factors are critical to the development of digital technology in the region. The analysis identifies countries that are leaders in digital development (Brazil, Mexico, Chile, Colombia, and Argentina), countries with an average level of digital technology development (Peru, Uruguay, Costa Rica, Paraguay, Panama, and the Dominican Republic), and those with slower progress (Bolivia, Ecuador, Venezuela, Guatemala, El Salvador, Honduras, Cuba, and Nicaragua). Based on this assessment, the study proposes and evaluates positive, negative, and neutral scenarios for the future of digital technology in Latin America over the next five years. The study concludes that a neutral scenario is the most likely, suggesting that, while advanced countries will maintain stable growth, lagging countries will experience accelerated, albeit still moderate, digitalization. This has key implications for regional competitiveness and digital inclusion. The study used methods of analysis, synthesis, classification, grouping, statistics, indexing, and scoring. This study uses the most recent data available (2022–2024) to provide an updated and comprehensive assessment of digital transformation in Latin America, reflecting post-pandemic dynamics and emerging digital trends such as AI and fintech growth. Full article

The COVID-19 pandemic disrupted medical education as the shift from face-to-face to remote teaching raised concerns about learning outcomes and well-being. However, while established schools’ adaptations have been widely studied, the challenges faced by new institutions in the pandemic’s aftermath remain underexplored. This research provides a valuable case study examining the motivations and concerns of faculty and students at a newly established medical school in the Philippines during its inaugural academic year. Employing a mixed-methods design, data were obtained via validated Likert-based questionnaires assessing motivation and survey questions eliciting concerns. Descriptive and inferential approaches were utilized to analyze data. Results show that faculty motivations were primarily intrinsic, whereas students were driven by a mix of intrinsic and extrinsic factors. Subgroup analyses revealed no difference in motivational profiles across demographic characteristics. Faculty were primarily concerned with their readiness for academic roles, use of modern teaching technologies, and ensuring effective student learning. Students’ concerns focused on training quality, institutional capacity, and the uncertainties of being the pioneer batch. Despite the pioneer cohort’s small size, this study highlighted the importance of understanding faculty and student motivations and concerns, already shaped by post-pandemic realities, to provide targeted support for new medical programs in the evolving post-pandemic landscape. Full article

The COVID-19 pandemic has accelerated digital transformation in various sectors, including higher education in South Africa. This study examines the readiness of information security functions in response to this rapid digital shift. Higher education institutions (HEIs) are transitioning to online platforms and digital tools, so the need to adapt security practices has become critical. The research investigates HEIs’ challenges in aligning their information security strategies with evolving digital initiatives. It explores how HEIs address technological change, staff awareness, and evolving security risks. By examining the relationship between digital transformation and information security, this study offers insights into strengthening the resilience and effectiveness of security functions within South African higher education. The findings highlight significant challenges, including the pace of technological change, inadequate staff training, and a lack of a security-conscious culture. Despite these hurdles, successful strategies such as promoting security awareness, policy adaptation, and improved governance frameworks are key to enhancing institutional preparedness. These insights can guide future efforts in improving information security practices in higher education, ensuring a more secure and resilient digital environment. Full article

The COVID-19 pandemic highlighted the critical importance of resilience and adaptability at both individual and organisational levels in navigating unprecedented challenges. This study introduces a novel Pandemic Resilience Competence Model, a framework that articulates eight key competences each for individuals and organisations to enhance preparedness and response in pandemic scenarios. Employing a qualitative approach, the research identifies the essential skills and organisational capacities required to mitigate the impacts of pandemics. Using 50 semi-structured interviews with professionals and managers working in healthcare services in Austria, Germany, Italy, Portugal and the United Kingdom, the model provides actionable insights for implementing processes to improve preparedness and response in pandemic scenarios for stakeholders, including policymakers, educators, and organisational leaders. Findings highlight the interdependence of individual and organisational competences, reinforcing the need for integrated strategies to build pandemic resilience. The conclusions advocate for embedding the competences within training and development initiatives, aiming to enhance collective readiness for future global health crises. Full article

The COVID-19 pandemic exposed critical gaps in healthcare infrastructure, particularly the lack of effective isolation anterooms for managing infectious diseases. This study presents TrainerWall, a cost-effective, portable anteroom designed for rapid deployment in both high-resource and resource-limited settings. TrainerWall features a modular, self-supporting structure with antimicrobial materials, integrated sanitization, and adaptable dimensions, ensuring seamless integration into healthcare environments without disrupting operations. Its dual function as an infection control measure and a training platform makes it particularly valuable for non-specialized healthcare workers. Pre-clinical evaluations conducted in simulated hospital environments have demonstrated their ease of deployment, procedural efficiency, and positive impact on infection control practices, particularly in non-specialized departments. Designed for quick assembly, disassembly, and transport, TrainerWall enhances healthcare readiness during outbreaks, offering a scalable solution where permanent infrastructure is lacking. Future integration of augmented reality and interactive guidance could further improve training and compliance. This innovation provides an accessible, adaptable approach to infection control, particularly in underserved regions and emergency response scenarios. Full article

Energy supply is currently considered a key area that is essential for the functioning of the entire society, remaining one of the most fundamental sectors of critical infrastructure worldwide. However, the functionality of energy systems is threatened by a number of threats from various areas, such as natural influences, technological threats, terrorism, and even state-supported organized attacks. For this reason, there is an active effort by all interested parties to achieve a sufficient resilience and sustainability level of these systems. Currently, various tools are used for this purpose, the essence of which is to ensure the preparedness of energy systems. Primarily, basic dependable systems aspects are applied according to the planning documentation and according to the N-1 principle from the transmission system code. These tools are functional and very proven in practice. However, the sprawling threat landscape and the COVID-19 pandemic have shown that the use of individual, separate tools may not comprehensively cover the entire area of preparedness, especially for unexpected events or expected events of unexpected dimensions. To address this challenge, the article takes up the professional abstract recommendation of ensuring the preparedness of the entire system comprehensively, i.e., by involving all possible tools, knowledge, and resources that the critical entity has. It proposes and tailors a Business Continuity Management System (BCMS) for the energy domain. The approach covers the entire management system of the organization, in which it establishes, implements, operates, monitors, reviews, maintains, and improves the continuity of activities in terms of key energy system functions. The aim is to ensure the sustainability of the functionality of the given systems within acceptable ranges. The article presents the targeted BCMS targets, building blocks, and representative implementation methods and tools. It is argued that the proposal is ready for application in the specific area of energy critical entities and systems by providing examples of partial implementation. Full article

A reliable, accessible, and high-quality blood supply is critical for the sustainment of any healthcare system. World events such as the COVID-19 pandemic have proven that maintaining the supply of blood presents a logistical challenge. The current blood supply is overseen by extensive donor programs around the world. In the United States, as in other countries, the need for blood has increased, with a decline in blood donations and increasing exclusions for blood donor qualification. While there is a need to improve blood donation participation, there is also need for new alternatives to traditional donation to ensure readiness to treat hemorrhagic shock common in the setting of trauma, as often occurs during a natural disaster or conflict. These operational medicine scenarios require significant blood availability which may tax the current blood supply chain. Aside from a walking blood bank (WBB) model for blood collection in suboptimal conditions, researchers have proposed alternatives for blood that include the manufacturing of blood from stem cell sources. Other alternatives include synthetic liquids that can carry oxygen such as Perfluoro-Chemicals (PFCs) and hemoglobin-based oxygen-carrying systems (HBCOs). Here, we review some of these alternatives to the traditional donor blood model. Researchers now have the technology that makes it feasible to develop blood alternatives that one day may supplement and help alleviate the limitations in blood supply. Full article

The novel coronavirus (COVID-19) pandemic has become one of the most devastating epidemics recorded in world history. The adverse impact of the pandemic is significant within the architecture, engineering, and construction (AEC) industry and other sectors of the economy. A considerable number of COVID-19 research studies have been undertaken in response to this global challenge across disciplines, with minimal output in the built environment. Thus, this study aims to identify, analyse, and visualise COVID-19 research trends in the AEC industry to unfold the sector’s response and readiness for possible future global pandemics. The study employed the scientometric approach to explore COVID-19 research outputs in the AEC industry, an aspect of health and safety in construction that has not been considered in past studies owing to the novel nature of the coronavirus pandemic. The findings revealed that the USA, China, and the United Kingdom were the top published countries and most affected as well. Co-occurring keywords analysis further showed that the predominant focus of scholarly outputs on the subject is around four clusters focusing on sustainable resilience, pandemic pathways and insights, land use and energy strategies, and indoor air excellence. Notwithstanding its limitations, the findings establish the need for the AEC industry to adopt innovative and holistically sustainable construction practices in the event of future disasters and pandemics. The findings of the study provide a robust theoretical foundation for researchers and stakeholders in the built environment, improving the sector’s mitigative and adaptive capacity in the potential occurrence of future pandemics. Full article

Recent major disasters, including the COVID-19 pandemic and floods in Europe, highlight the unpredictability of crises and the necessity for systemic preparedness at all levels of crisis management, including pre-hospital emergency medical services. Paramedics observed, under these challenging conditions (but not exclusively during them), cases of insufficient knowledge and skills in providing pre-hospital medical care, which lead to inadequate or prolonged decision making in delivering assistance. For this reason, the authors aimed to determine the extent to which such situations occur and to examine their causes, focusing on potential gaps and shortcomings in the education of paramedics. This study examines the impact of educational systems on the professional preparedness of paramedics in V4 European countries (the Slovak Republic, the Czech Republic, Hungary, and Poland) during pre-hospital care through a questionnaire survey. A survey involving over 1600 respondents revealed significant disparities in perceived knowledge and skill gaps, with Poland demonstrating the highest deficiencies (78%) and the Slovak Republic the lowest (57%). Key factors influencing these gaps included the frequency of external educational and training activities, years of experience, and expertise in managing critical conditions. The findings underscore the importance of innovative technologies, such as simulations and virtual reality, in enhancing paramedic training, along with integrating digital solutions across all phases of disaster management. Recommendations focus on strengthening system resilience, fostering interdisciplinary approaches, and improving system sustainability and adaptability. By using the results obtained and leveraging technological advances, the study aims to contribute to more effective crisis preparedness, population protection, and sustainable development goals (SDGs), namely (3, 4, 9, and 11), especially in the field of crisis management. This reinforces the broader role of SDGs in building more robust, future-ready disaster management frameworks. Full article