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3,797 Results Found

  • Review
  • Open Access
32 Citations
7,251 Views
13 Pages

The Crazy Ovary

  • Philippe Monget,
  • Ken McNatty and
  • Danielle Monniaux

18 June 2021

From fetal life until senescence, the ovary is an extremely active tissue undergoing continuous structural and functional changes. These ever-changing events are best summarized by a quotation attributed to Plato when describing motion in space and t...

(This article belongs to the Special Issue Genetic and Genomic Regulation of Ovarian and Testicular Functions in Animals)
  • Case Report
  • Open Access
1 Citations
2,125 Views
3 Pages

Ectopic Ovary: One New Location

  • Mounzer Dgheem and
  • Hosam Salman

Ectopic ovarian tissue is a rare gynecologic condition. Accessory ovaries were defined as excess ovarian tissue adjacent and connected to a normal ovary, while supernumerary ovaries were described as those ovaries situated away from normal ones. The...

  • Review
  • Open Access
100 Citations
11,782 Views
13 Pages

Estrogen Receptors in Polycystic Ovary Syndrome

  • Xue-Ling Xu,
  • Shou-Long Deng,
  • Zheng-Xing Lian and
  • Kun Yu

21 February 2021

Female infertility is mainly caused by ovulation disorders, which affect female reproduction and pregnancy worldwide, with polycystic ovary syndrome (PCOS) being the most prevalent of these. PCOS is a frequent endocrine disease that is associated wit...

(This article belongs to the Section Cell Signaling)
  • Article
  • Open Access
5 Citations
13,014 Views
8 Pages

25 February 2022

Because the effects of age, menopausal status, weight and body mass index (BMI) on ovarian detectability by transvaginal ultrasound (TVS) have not been established, we determined their contributions to TVS visualization of the ovaries when one or bot...

  • Article
  • Open Access
2 Citations
3,472 Views
14 Pages

Role of RGMc as a Neogenin Ligand in Follicular Development in the Ovary

  • Yu Jin Kim,
  • YoungJoon Park,
  • Yeo Reum Park,
  • Young Sang Kim and ,
  • Hye Ran Lee,
  • Sang Jin Lee,
  • Myung Joo Kim,
  • KyuBum Kwack,
  • Jung Jae Ko and
  • Jae Ho Lee
  • + 5 authors+ 0 author

There is currently no cure for infertility in women with a poor ovarian response (POR). Neogenin is reported to be abundantly expressed in the ovary; however, its role in mammalian follicular development is unclear and its ligand and signaling pathwa...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
18 Citations
11,812 Views
10 Pages

Removal of Toxin (Tetrodotoxin) from Puffer Ovary by Traditional Fermentation

  • Kensaku Anraku,
  • Kiku Nonaka,
  • Toshitaka Yamaga,
  • Takatoshi Yamamoto and ,
  • Min-Chul Shin,
  • Masahito Wakita,
  • Ayaka Hamamoto and
  • Norio Akaike
  • + 3 authors+ 0 author

18 January 2013

The amounts of puffer toxin (tetrodotoxin, TTX) extracted from the fresh and the traditional Japanese salted and fermented “Nukazuke” and “Kasuzuke” ovaries of Takifugu stictonotus (T. stictonotus) were quantitatively analyzed in the voltage-dependen...

(This article belongs to the Special Issue Toxins from Aquatic Organisms)
  • Review
  • Open Access
15 Citations
10,314 Views
11 Pages

Ovarian Torsion in Polycystic Ovary Syndrome: A Potential Threat?

  • Iason Psilopatis,
  • Christos Damaskos,
  • Nikolaos Garmpis,
  • Kleio Vrettou and ,
  • Anna Garmpi,
  • Efstathios A. Antoniou,
  • Athanasios Chionis,
  • Konstantinos Nikolettos,
  • Konstantinos Kontzoglou and
  • Dimitrios Dimitroulis
  • + 5 authors+ 0 author

10 September 2023

Polycystic ovary syndrome (PCOS) constitutes the most prevalent endocrine disorder in women of reproductive age worldwide. Given the increased risk of ovarian torsion in the presence of large ovarian cysts, polycystic ovarian syndrome could be regard...

(This article belongs to the Special Issue Advances in Polycystic Ovary Syndrome Research: From Molecular Mechanisms to Therapeutic Strategies)
  • Article
  • Open Access
13 Citations
5,846 Views
15 Pages

Classification of Atretic Small Antral Follicles in the Human Ovary

  • Fu Wei,
  • Xueying Fan,
  • Julieta S. del Valle,
  • Joyce D. Asseler and ,
  • Lotte E. van der Meeren,
  • Hui Cheng,
  • Bernard A. J. Roelen,
  • Leoni A. Louwe,
  • Gonneke S. K. Pilgram and
  • Susana M. Chuva de Sousa Lopes
  • + 7 authors+ 2 authors

28 November 2023

The reproductive lifespan in humans is regulated by a delicate cyclical balance between follicular recruitment and atresia in the ovary. The majority of the small antral follicles present in the ovary are progressively lost through atresia without re...

(This article belongs to the Special Issue Ovarian Reserve Disorders: Molecular Mechanisms and Regulation)
  • Review
  • Open Access
52 Citations
26,451 Views
13 Pages

Polycystic Ovary Syndrome: Pathophysiology and Controversies in Diagnosis

  • Duaa Fahs,
  • Dima Salloum,
  • Mona Nasrallah and
  • Ghina Ghazeeri

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder that commonly affects women in the reproductive age group. The disorder has features that propose a blend of functional reproductive disorders, such as anovulation and hyperandr...

(This article belongs to the Special Issue Diagnosis of Polycystic Ovary Syndrome (PCOS): State-of-the-Art and Open Questions)
  • Article
  • Open Access
5 Citations
2,867 Views
17 Pages

Deletion of ddx4 Ovary-Specific Transcript Causes Dysfunction of Meiosis and Derepress of DNA Transposons in Zebrafish Ovaries

  • Yuanyuan Chen,
  • Xing Lin,
  • Jing Dai,
  • Yifan Bai and ,
  • Fei Liu and
  • Daji Luo
  • + 1 author+ 0 author

16 December 2024

Alternative splicing of ddx4 (DEAD-box helicase 4), a key germline marker gene, has been reported to generate sex-specific transcripts in zebrafish gonads. The biological functions and regulatory mechanisms of the ddx4 ovary-specific transcript (ddx4...

(This article belongs to the Special Issue The Biology of Animal Reproduction)
  • Feature Paper
  • Article
  • Open Access
2 Citations
3,421 Views
13 Pages

Comparative Metabolomic Analysis of Multi-Ovary Wheat under Heterogeneous Cytoplasm Suppression

  • Jialin Guo,
  • Ying Li,
  • Yulong Song,
  • Gaisheng Zhang and
  • Huiyan Zhao

30 March 2021

The multi-ovary trait of wheat inbred line DUOII is controlled by a dominant gene whose expression can be suppressed by the heterogeneous cytoplasm of TeZhiI (TZI), another inbred line with the nucleus of common wheat and the cytoplasm of Aegilops. D...

(This article belongs to the Section Crop Breeding and Genetics)
  • Review
  • Open Access
33 Citations
8,057 Views
8 Pages

2 October 2019

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females, and is characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology based on ultrasound. Controversy surrounds the optimum diagn...

(This article belongs to the Special Issue Polycystic Ovary Syndrome)
  • Case Report
  • Open Access
7 Citations
4,916 Views
13 Pages

5 November 2022

The primary ovarian carcinoid tumor is a very rare ovarian tumor, which accounts for approximately 0.5% to 1.7% of all carcinoids and 1% of ovarian cancer. According to its histopathological features, it can be divided into four categories: insular,...

(This article belongs to the Special Issue Recent Advances in Gynecologic Oncology: Diagnosis and Management)
  • Article
  • Open Access
76 Citations
6,793 Views
21 Pages

The Effect of Oxidative Stress on the Chicken Ovary: Involvement of Microbiota and Melatonin Interventions

  • Jianping Wang,
  • Ru Jia,
  • Haojie Gong,
  • Pietro Celi and ,
  • Yong Zhuo,
  • Xuemei Ding,
  • Shiping Bai,
  • Qiufeng Zeng,
  • Huadong Yin and
  • Keying Zhang
  • + 8 authors+ 3 authors

6 September 2021

The poultry ovary is used as a classic model to study ovarian biology and ovarian cancer. Stress factors induced oxidative stress to cause follicle atresia, which may be a fundamental reason for the reduction in fertility in older laying hens or in a...

(This article belongs to the Special Issue Antioxidants in Animal Feed)
  • Feature Paper
  • Article
  • Open Access
5 Citations
2,997 Views
19 Pages

Aging Alters mRNA Processing in the Mouse Ovary

  • Kevin Vo,
  • Grace J. Pei,
  • Ramkumar Thiyagarajan,
  • Patrick E. Fields and
  • M. A. Karim Rumi

30 June 2025

Aging in females affects the ovaries before any other organ. This has a significant impact on women’s health. Aging results in the gradual depletion of ovarian follicles and a decline in oocyte quality. Studies have shown that cellular changes...

(This article belongs to the Section Tissues and Organs)
  • Article
  • Open Access
6 Citations
7,068 Views
9 Pages

8 June 2023

This study aims to determine the test–retest reliability and to confirm the domain structures of the Dutch version of the modified polycystic ovary syndrome questionnaire (mPCOSQ) and the Polycystic Ovary Syndrome Quality of Life Scale (PCOSQOL...

(This article belongs to the Special Issue Polycystic Ovary Syndrome (PCOS): State of the Art)
  • Article
  • Open Access
7 Citations
5,309 Views
21 Pages

8 December 2021

The female reproductive system, ovary structure and ultrastructure of Trypophloeus klimeschi (Coleoptera: Curculionidae: Scolytinae) were investigated using light microscopy, scanning electron microscopy, and transmission electron microscopy. Its fem...

(This article belongs to the Special Issue Beetle Diversity)
  • Article
  • Open Access
10 Citations
3,680 Views
7 Pages

Characteristics and Risk Factors for Ischemic Ovary Torsion in Children

  • Jason Tsai,
  • Jin-Yao Lai,
  • Yi-Hao Lin,
  • Ming-Han Tsai and ,
  • Pai-Jui Yeh,
  • Chyi-Liang Chen and
  • Yi-Jung Chang
  • + 2 authors+ 0 author

6 February 2022

Identifying ischemic ovary as a complication of ovary torsion (OT) is a significant challenge in children. This study identified risk factors for ischemic OT among pediatric OT patients to prevent delayed treatment. This retrospective study included...

  • Article
  • Open Access
14 Citations
3,068 Views
10 Pages

Oncostatin M Is Related to Polycystic Ovary Syndrome-Case Control Study

  • Figen Efe Camili,
  • Merve Akis,
  • Ertan Adali,
  • Adnan Adil Hismiogullari and ,
  • Mine Islimye Taskin,
  • Gurhan Guney and
  • Selim Afsar
  • + 2 authors+ 0 author

Background: Oncostatin M, a novel adipokine, plays a role in oogenesis, lipogenesis, and inflammation and may contribute to polycystic ovary syndrome pathogenesis and related metabolic problems. Adipokines are believed to contribute to developing pol...

(This article belongs to the Special Issue Polycystic Ovary Syndrome (PCOS): Genetic, Hormonal and Metabolic Aspects)
  • Review
  • Open Access
44 Citations
14,223 Views
19 Pages

14 October 2018

Background: Throughout history, menopause has been regarded as a transition in a woman’s life. With the increase in life expectancy, women now spend more than a third of their lives in menopause. During these years, women may experience intoler...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Review
  • Open Access
91 Citations
14,602 Views
20 Pages

Retinoic Acid and Germ Cell Development in the Ovary and Testis

  • Tsutomu Endo,
  • Maria M. Mikedis,
  • Peter K. Nicholls,
  • David C. Page and
  • Dirk G. de Rooij

24 November 2019

Retinoic acid (RA), a derivative of vitamin A, is critical for the production of oocytes and sperm in mammals. These gametes derive from primordial germ cells, which colonize the nascent gonad, and later undertake sexual differentiation to produce oo...

(This article belongs to the Special Issue Retinoids in Embryonic Development)
  • Review
  • Open Access
26 Citations
8,074 Views
12 Pages

Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent

  • Nathalie di Clemente,
  • Chrystèle Racine and
  • Rodolfo A. Rey

This article reviews the main findings on anti-Müllerian hormone (AMH) and its involvement in the pathogenesis of polycystic ovary syndrome (PCOS) and its male equivalent. In women, AMH is produced by granulosa cells from the mid-fetal life to m...

(This article belongs to the Special Issue Molecular Research on Polycystic Ovary Syndrome (PCOS))
  • Review
  • Open Access
158 Citations
14,455 Views
25 Pages

MicroRNAs Related to Polycystic Ovary Syndrome (PCOS)

  • Anja Elaine Sørensen,
  • Marie Louise Wissing,
  • Sofia Salö,
  • Anne Lis Mikkelsen Englund and
  • Louise Torp Dalgaard

25 August 2014

Polycystic ovary syndrome (PCOS) is the most common, though heterogeneous, endocrine aberration in women of reproductive age, with high prevalence and socioeconomic costs. The syndrome is characterized by polycystic ovaries, chronic anovulation and h...

(This article belongs to the Special Issue miRNA Regulation)
  • Article
  • Open Access
2 Citations
1,701 Views
14 Pages

Extracorporal Ovary Bioreactor System with Oxygen Supply and Drug Delivery Option

  • Karin Bundschu,
  • Sabine Eberhart,
  • Florian Maiss,
  • Isabella Milic and
  • Martin Hessling

Young women who have survived cancer may have lost their fertility due to cytotoxic treatments like chemotherapy or irradiation. So far, oocyte or ovarian tissue cryopreservation are well-known and well-used opportunities for fertility preservation p...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
3 Citations
4,074 Views
17 Pages

Impact of Hypocaloric Dietary Intervention on Phenotypic Presentations of Polycystic Ovary Syndrome (PCOS)

  • Faith E. Carter,
  • Brittany Y. Jarrett,
  • Alexis L. Oldfield,
  • Heidi Vanden Brink and ,
  • Joy Y. Kim and
  • Marla E. Lujan
  • + 1 author+ 0 author

4 July 2025

Background/Objective: Lifestyle intervention is recommended as first-line treatment for polycystic ovary syndrome (PCOS). This pilot study aimed to determine if a short-term hypocaloric dietary intervention induced changes in the phenotypic presentat...

(This article belongs to the Special Issue Nutritional Effects on Women’s Reproductive Health and Disease)
  • Article
  • Open Access
8 Citations
2,952 Views
13 Pages

QTL Mapping for Ovary- and Fruit-Related Traits in Cucumis sativus-C. hystrix Introgression Line IL52

  • Yuhui Wang,
  • Yu Fang,
  • Shixiong Ning,
  • Lei Xia and ,
  • Jinyi Zhan,
  • Zhilong Yang,
  • Chunyan Cheng,
  • Qunfeng Lou,
  • Ji Li and
  • Jinfeng Chen
  • + 5 authors+ 0 author

23 May 2023

IL52 is a valuable introgression line obtained from interspecific hybridization between cultivated cucumber (Cucumis sativus L., 2n = 14) and the wild relative species C. hystrix Chakr. (2n = 24). IL52 exhibits high resistance to a number of diseases...

(This article belongs to the Special Issue Cucumber Genetics and Breeding - a Themed Issue in Memory of Academician Feng Hou (1928 - 2020))
  • Article
  • Open Access
4 Citations
2,225 Views
13 Pages

Effects of Different Photoperiods on the Transcriptome of the Ovary and Small White Follicles in Zhedong White Geese

  • Tao Huang,
  • Meina Fei,
  • Xiaolong Zhou,
  • Ke He and ,
  • Songbai Yang and
  • Ayong Zhao
  • + 1 author+ 0 author

23 September 2024

Photoperiod can regulate the broodiness of geese and thus increase their egg-laying rate. The laying performance of geese is mainly determined by ovary and follicle development. To understand the effect of photoperiod on the ovary and small white fol...

(This article belongs to the Section Poultry)
  • Article
  • Open Access
24 Citations
5,493 Views
10 Pages

Metabolic Deregulations in Patients with Polycystic Ovary Syndrome

  • Marzena Jabczyk,
  • Justyna Nowak,
  • Paweł Jagielski,
  • Bartosz Hudzik and ,
  • Karolina Kulik-Kupka,
  • Aleksander Włodarczyk,
  • Katarzyna Lar and
  • Barbara Zubelewicz-Szkodzińska
  • + 3 authors+ 0 author

17 February 2023

Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic diso...

(This article belongs to the Special Issue Prooxidant–Antioxidant and Inflammation Markers in Metabolic Syndrome and Its Complications)
  • Article
  • Open Access
26 Citations
4,226 Views
20 Pages

Perfusion and Ultrasonication Produce a Decellularized Porcine Whole-Ovary Scaffold with a Preserved Microarchitecture

  • Gustavo Henrique Doná Rodrigues Almeida,
  • Leandro Norberto da Silva-Júnior,
  • Mariana Sversut Gibin,
  • Henrique dos Santos and ,
  • Bianca de Oliveira Horvath-Pereira,
  • Leticia Beatriz Mazo Pinho,
  • Mauro Luciano Baesso,
  • Francielle Sato,
  • Luzmarina Hernandes and
  • Ana Claudia Oliveira Carreira
  • + 8 authors+ 3 authors

15 July 2023

The application of decellularized scaffolds for artificial tissue reconstruction has been an approach with great therapeutic potential in regenerative medicine. Recently, biomimetic ovarian tissue reconstruction was proposed to reestablish ovarian en...

  • Review
  • Open Access
67 Citations
19,706 Views
13 Pages

Insulin Metabolism in Polycystic Ovary Syndrome: Secretion, Signaling, and Clearance

  • Rok Herman,
  • Jaka Sikonja,
  • Mojca Jensterle,
  • Andrej Janez and
  • Vita Dolzan

5 February 2023

Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age. Its heterogeneous clinical presentation is characterized by hyperandrogenemia, reproductive changes, polycystic ovary morphology, and i...

(This article belongs to the Section Molecular Endocrinology and Metabolism)
  • Article
  • Open Access
17 Citations
9,562 Views
15 Pages

Transcriptome Analysis Identifies Key Candidate Genes Mediating Purple Ovary Coloration in Asiatic Hybrid Lilies

  • Leifeng Xu,
  • Panpan Yang,
  • Suxia Yuan,
  • Yayan Feng and ,
  • Hua Xu,
  • Yuwei Cao and
  • Jun Ming
  • + 2 authors+ 0 author

20 November 2016

Lily tepals have a short lifespan. Once the tepals senesce, the ornamental value of the flower is lost. Some cultivars have attractive purple ovaries and fruits which greatly enhance the ornamental value of Asiatic hybrid lilies. However, little is k...

(This article belongs to the Special Issue Anthocyanins)
  • Article
  • Open Access
6 Citations
3,917 Views
21 Pages

25 January 2022

Automated detection of ovarian follicles in ultrasound images is much appreciated when its effectiveness is comparable with the experts’ annotations. Today’s best methods estimate follicles notably worse than the experts. This paper descr...

(This article belongs to the Special Issue Deep Image Semantic Segmentation and Recognition)
  • Article
  • Open Access
5 Citations
2,707 Views
11 Pages

Do Aging and Parity Affect VEGF-A/VEGFR Content and Signaling in the Ovary?—A Mouse Model Study

  • Valentina Di Nisio,
  • Gianna Rossi,
  • Alessandro Chiominto,
  • Ezio Pompili and
  • Sandra Cecconi

7 February 2023

In this study, the effects of aging and parity on VEGF-A/VEGFR protein content and signaling in the mice ovaries were determined. The research group consisted of nulliparous (virgins, V) and multiparous (M) mice during late-reproductive (L, 9–1...

(This article belongs to the Special Issue Biology and Toxicology of Gametes, Embryos, and Cancer Cells in Reproductive System)
  • Review
  • Open Access
23 Citations
11,933 Views
14 Pages

Glycemic Index and Glycemic Load Estimates in the Dietary Approach of Polycystic Ovary Syndrome

  • Aspasia Manta,
  • Stavroula A. Paschou,
  • Georgia Isari,
  • Ioanna Mavroeidi and ,
  • Sophia Kalantaridou and
  • Melpomeni Peppa
  • + 1 author+ 0 author

7 August 2023

Polycystic ovary syndrome is a common endocrine disorder characterized by hormonal imbalances and various metabolic abnormalities linked to insulin resistance via a vicious cycle. Genetic and environmental factors underlie its pathogenesis and evolut...

  • Article
  • Open Access
2 Citations
3,566 Views
13 Pages

26 August 2020

Although its function in mammalian gonads has been gradually recognized, the expression and function of calretinin (CALB2)—a Ca2+-binding protein—in the testis and ovary of fish are still unclear. Here, we identified the cDNA sequences of...

(This article belongs to the Special Issue Mineral Nutrition and Metabolism in Fish)
  • Article
  • Open Access
59 Citations
9,586 Views
16 Pages

The Essential Role of Vitellogenin Receptor in Ovary Development and Vitellogenin Uptake in Bactrocera dorsalis (Hendel)

  • Lin Cong,
  • Wen-Jia Yang,
  • Xuan-Zhao Jiang,
  • Jin-Zhi Niu and ,
  • Guang-Mao Shen,
  • Chun Ran and
  • Jin-Jun Wang
  • + 2 authors+ 0 author

7 August 2015

The vitellogenin receptor (VgR) functions as an essential component in uptaking and transporting vitellogenin (Vg) in female adults, which is involved in ovary development and oviposition. This study aimed to clarify the molecular characteristics and...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
15 Citations
4,562 Views
13 Pages

Extracts of Common Vegetables Inhibit the Growth of Ovary Cancer Cells

  • Paulina Furdak,
  • Natalia Pieńkowska,
  • Grzegorz Bartosz and
  • Izabela Sadowska-Bartosz

20 August 2022

There is recent interest in a diet that can be recommended for patients suffering from cancer. In this respect, the effects were studied of the extracts of several common fruits, herbs and vegetables on the viability of two human ovary cancer cell li...

(This article belongs to the Section Plant Foods)
  • Opinion
  • Open Access
55 Citations
14,427 Views
12 Pages

Polycystic Ovary Syndrome: Challenges and Possible Solutions

  • Yue Che,
  • Jie Yu,
  • Yu-Shan Li,
  • Yu-Chen Zhu and
  • Tao Tao

14 February 2023

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. This syndrome not only impairs female fertility but also increases the risk of obesity, diabetes, dyslipidemia, cardiovascular diseases, psyc...

(This article belongs to the Special Issue Polycystic Ovary Syndrome: Aetiology, Diagnosis, Treatment and Future Perspectives)
  • Review
  • Open Access
98 Citations
21,174 Views
21 Pages

Metabolomic Insight into Polycystic Ovary Syndrome—An Overview

  • Anna Rajska,
  • Magdalena Buszewska-Forajta,
  • Dominik Rachoń and
  • Michał Jan Markuszewski

Searching for the mechanisms of the polycystic ovary syndrome (PCOS) pathophysiology has become a crucial aspect of research performed in the last decades. However, the pathogenesis of this complex and heterogeneous endocrinopathy remains unknown. Th...

(This article belongs to the Special Issue Novel Physiology and Molecular Pathology of Reproduction, Novel Treatments of Infertility)
  • Article
  • Open Access
30 Citations
14,388 Views
12 Pages

Quality of Life of Women with Polycystic Ovary Syndrome

  • Natalia Ligocka,
  • Karolina Chmaj-Wierzchowska,
  • Katarzyna Wszołek,
  • Maciej Wilczak and
  • Katarzyna Tomczyk

9 February 2024

Background and Objectives: Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by multiple hormonal and metabolic abnormalities, including insulin resistance, hyperandrogenism, and disturbances in lipid and carbohydrate metabolism...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
17 Citations
3,867 Views
11 Pages

Uptake and Metabolization of Serotonin by Granulosa Cells Form a Functional Barrier in the Mouse Ovary

  • Nina M. Alyoshina,
  • Maria D. Tkachenko,
  • Lyudmila A. Malchenko,
  • Yuri B. Shmukler and
  • Denis A. Nikishin

27 November 2022

Serotonin (5-HT) plays an essential role in regulating female reproductive function in many animals. 5-HT accumulates in the mammalian ovary with the involvement of membrane serotonin transporter SERT and is functionally active in the oocytes of grow...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
5 Citations
2,790 Views
13 Pages

HIF-1α Promotes Luteinization via NDRG1 Induction in the Human Ovary

  • Akemi Nishigaki,
  • Mitsuaki Ishida,
  • Hiroaki Tsubokura,
  • Yoji Hisamatsu and ,
  • Yoshinobu Hirose and
  • Hidetaka Okada
  • + 1 author+ 0 author

Background/Objectives: Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that plays a crucial role in various physiological and pathological processes of the ovary. However, the timing of HIF-1α expression and its speci...

(This article belongs to the Section Cell Biology and Pathology)
  • Concept Paper
  • Open Access
46 Citations
14,408 Views
13 Pages

Reconsidering the Polycystic Ovary Syndrome (PCOS)

  • Norbert Gleicher,
  • Sarah Darmon,
  • Pasquale Patrizio and
  • David H. Barad

Though likely the most common clinical diagnosis in reproductive medicine, the Polycystic Ovary Syndrome (PCOS) is still only poorly understood. Based on previously published research, and here newly presented supportive evidence, we propose to repla...

(This article belongs to the Special Issue Molecular Research on Polycystic Ovary Syndrome (PCOS))
  • Article
  • Open Access
11 Citations
5,966 Views
19 Pages

Ovule Development and in Planta Transformation of Paphiopedilum Maudiae by Agrobacterium-Mediated Ovary-Injection

  • Bai-Xue Luo,
  • Li Zhang,
  • Feng Zheng,
  • Kun-Lin Wu and ,
  • Lin Li,
  • Xin-Hua Zhang,
  • Guo-Hua Ma,
  • Jaime A. Teixeira da Silva,
  • Lin Fang and
  • Song-Jun Zeng
  • + 5 authors+ 0 author

In this paper, the development of the Paphiopedilum Maudiae embryo sac at different developmental stages after pollination was assessed by confocal laser scanning microscopy. The mature seeds of P. Maudiae consisted of an exopleura and a spherical em...

(This article belongs to the Collection Genetics and Molecular Breeding in Plants)
  • Article
  • Open Access
17 Citations
8,507 Views
13 Pages

Influence of Vitamin D on the Incidence of Metabolic Syndrome and Hormonal Balance in Patients with Polycystic Ovary Syndrome

  • Katarzyna Lejman-Larysz,
  • Anna Golara,
  • Marta Baranowska,
  • Mateusz Kozłowski and ,
  • Paweł Guzik,
  • Iwona Szydłowska,
  • Jolanta Nawrocka-Rutkowska,
  • Elżbieta Sowińska-Przepiera,
  • Aneta Cymbaluk-Płoska and
  • Agnieszka Brodowska
  • + 5 authors+ 0 author

29 June 2023

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that affects 8–13% of women of reproductive age. It is one of the most common causes of infertility and is associated with hyperandrogenism in the form of hirsutism and acne...

(This article belongs to the Special Issue Insights into the Role of Vitamin D in the Prevention and Control of Cancer and Other Chronic Noncommunicable Diseases)
  • Article
  • Open Access
12 Citations
3,173 Views
19 Pages

8 March 2023

A TMT-based (Tandem Mass Tag) liquid chromatography-tandem mass spectrometry (LC-MS/MS) proteomics approach was employed to explore differentially expressed proteins (DEPs) and KEGG pathways in hepatopancreas of 5 ovary stages. In total, 17,999 pepti...

(This article belongs to the Section Aquatic Animals)
  • Communication
  • Open Access
4 Citations
5,061 Views
10 Pages

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. A substantial proportion of patients with PCOS are either overweight or obese, and excess body weight aggravates the hormonal, reproductive and metabolic ma...

(This article belongs to the Special Issue Molecular Research on Polycystic Ovary Syndrome (PCOS) 2.0)
  • Article
  • Open Access
1 Citations
1,623 Views
14 Pages

Queen Loss Remodels Brain Dopamine and Hormonal Pathways During Worker Ovary Activation in Apis mellifera

  • Meijiao Zhao,
  • Jiangli Wu,
  • Weipeng Kang,
  • Qiaohong Wei and ,
  • Shufa Xu,
  • Honggang Guo and
  • Bin Han
  • + 2 authors+ 0 author

12 March 2026

In honey bees, reproductive division of labor is maintained by social suppression of worker fertility, yet queen loss can trigger ovary activation in workers. Here, we tested whether endogenous dopaminergic signaling is progressively remodeled across...

(This article belongs to the Special Issue Biology and Conservation of Honey Bees)
  • Article
  • Open Access
1,895 Views
11 Pages

9 August 2024

Activin is a dimeric growth factor with diverse biological activities in vertebrates. This study aimed to investigate the regulatory role of the activin signaling pathway in the ovary of the endangered, cultured sturgeon species Acipenser sinensis. O...

(This article belongs to the Section Animal Physiology)
  • Interesting Images
  • Open Access
168 Views
6 Pages

9 October 2026

Ectopic adrenal cortical tissue (EACT) is an uncommon developmental heterotopia and is exceptionally rare in the ovary of adult women. A 52-year-old woman, 6 years after menopause, was evaluated for progressive enlargement of a uterine leiomyoma and...

(This article belongs to the Section Pathology and Molecular Diagnostics)

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