Search Results (830)

Long-term success of root canal therapy depends not only on effective disinfection but also on durable sealing of the obturated canal system. However, currently available sealers still face persistent challenges in balancing handling, interfacial stability, bioactivity, and antibacterial performance. Here, we developed an injectable calcium silicate-based root canal sealer reinforced with mesoporous bioactive glass nanoparticles (MBGN) to improve sealing-related performance. The formulation integrated a hydration-active calcium silicate matrix with a mesoporous bioactive component while maintaining practical handling characteristics. MBGN incorporation enhanced dentin-associated mineralization, promoted intratubular crystal deposition, reduced apical microleakage, and decreased internal porosity after obturation. The 5% MBG formulation showed the most favorable sealing profile, reducing the dye penetration depth from 2.68 ± 0.41 mm in the 0% MBG group to 1.87 ± 0.32 mm, together with decreased open and closed pore parameters in the apical region. In parallel, the MBGN-reinforced sealer preserved acceptable cytocompatibility and exhibited stronger antibacterial activity against Streptococcus mutans than the reference formulations. The improved performance may be associated with effective initial adaptation and bioactive interfacial densification. Together, these findings suggest that MBGN incorporation may be a promising route for engineering more bioactive calcium silicate sealers with improved sealing stability and antibacterial function for endodontic applications. Full article

Background and Objectives: Accelerated rehabilitation after anterior cruciate ligament reconstruction (ACLR) is widely implemented, yet its definition and distinguishing characteristics remain inconsistently described in the literature. This scoping review examined how accelerated rehabilitation after ACLR is defined, described common protocol features, and identified elements distinguishing it from conventional rehabilitation. Materials and Methods: A scoping review was conducted using systematic searches of Medline (PubMed), Embase, and Web of Science from 1 April 1967 to 26 October 2025. Studies including patients aged 16 years or older who underwent primary ACLR that reported any form of accelerated rehabilitation or early progression relative to conventional protocols were eligible for inclusion. Results: Of 6002 screened records, 64 studies met the inclusion criteria. Accelerated rehabilitation was consistently characterized by early restoration of knee range of motion, early full weight-bearing, rapid gait normalization, early initiation of closed and open kinetic chain exercises, and avoidance of prolonged immobilization. However, definitions varied substantially across studies. Substantial heterogeneity was observed in progression timelines, bracing and crutch use, and return-to-sport criteria. Conclusions: Accelerated rehabilitation after ACLR appears to represent a brace-free, criterion-based, function-oriented approach emphasizing early restoration of knee extension, progressive loading, and individualized progression rather than simply shortened timelines. Establishing consensus definitions and standardized reporting is necessary to improve comparability across studies and facilitate translation into clinical practice. Full article

The dielectric spectrum of vegetable oils has been widely used to explore relationships with their physicochemical quality parameters. A Cole–Cole relaxation with a characteristic frequency around 200–300 MHz is commonly reported at 25 °C. More recently, the efficient heating of vegetable oils at 2450 MHz has been attributed to the relaxation of a glycerol component (10% by weight) in the triglycerides of vegetable oils. This study presents a method to identify more than one relaxation process using a NanoVNA directly connected to a 5-pin open-ended coaxial probe. The reflection coefficient S₁₁(f) was measured and transformed into the relative complex permittivity ε(f) using the Marsland transformation. The resulting spectra were analyzed with the Cole–Cole model and with the Maxwell model incorporating two Debye relaxations. The method was validated over the 50–900 MHz range using silicone oil, glycerol, and pure triglycerides. The static dielectric constant was obtained with high accuracy. For the first time, two relaxations were observed in oleic oils, including a low-frequency relaxation between 86 and 96 MHz, close to the 100 MHz relaxation of glycerol at 25 °C. Additionally, the low-cost equipment and the open-source software make the method accessible to laboratories with limited resources. Full article

Oscillating water column wave energy converters require self-rectifying turbines capable of maintaining stable performance under bidirectional airflow. This study numerically investigates the aerodynamic performance and internal flow characteristics of an axial-flow impulse turbine using OpenFOAM under both uniform and reciprocating airflow conditions. Rotor motion was modeled using the Multiple Reference Frame approach, and the numerical model was validated against experimental data for one-way flow at an inlet velocity of 8.71 m s⁻¹ and rotational speeds ranging from 300 to 1300 rpm. The CFD results successfully reproduced the experimental efficiency trend, yielding a peak efficiency of η = 0.4269 at 700 rpm and ϕ ≈ 0.95, which closely aligns with the experimental peak efficiency of η = 0.4425. Validation metrics demonstrated a high degree of accuracy, with an RMSE of 0.0219, a mean absolute error of 0.0197, a maximum absolute error of 0.0399, a squared Pearson correlation coefficient of 0.826, and a peak-efficiency difference of 3.5%. Flow-field analysis revealed that low rotational speeds resulted in high outlet velocities and incomplete energy extraction, whereas excessive rotational speeds caused flow misalignment, downstream vortex formation, and additional aerodynamic losses. Under reciprocating flow conditions, characterized by a sinusoidal velocity amplitude of 8.71 m s⁻¹ and periods of 0.5–2.0 s at 700 rpm, both input and torque coefficients exhibited hysteresis, with the strongest loops observed at the shortest periods. Examinations of streamline, pressure, and velocity distributions indicated that residual flow during flow reversal alters the effective inlet direction in the subsequent half-cycle, resulting in flow memory and a phase-dependent turbine response. As the present computational domain excludes the OWC chamber, these findings characterize turbine-level aerodynamic performance rather than the complete system power coefficient. Full article

Commercial-scale dairy farms produce large volumes of manure, posing environmental, animal health, and public health risks due to persistent pathogens and the accumulation of organic pollutants. This field-scale study evaluated the effects of covered anaerobic lagoons (CLs) and open facultative lagoons (OLs) on microbial reduction, solids stabilization, and manure biogeochemical characteristics on commercial dairy farms in California’s Central Valley during the summer months. Manure samples collected from lagoon inlets, outlets, and secondary lagoons were analyzed for Escherichia coli, total solids (TS), volatile solids (VS), and genomic DNA degradation. CL systems achieved substantially greater E. coli reductions (98.38%; 1.82 log) than OL systems (54.88%; 0.35 log), indicating enhanced pathogen suppression under anaerobic conditions. Progressive declines in genomic DNA concentrations and electropherogram signal intensities across treatment stages further demonstrated microbial biomass degradation during storage. In the CL system, TS concentrations decreased from approximately 0.985% at the inlet to 0.485% at the outlet, representing a 50.7% reduction, with an additional 56% reduction observed in the secondary lagoon. For moisture content, both CL and OL systems exhibited increases of approximately 0.37–0.5% from their respective inlets to outlets, with only marginal increases observed in the secondary lagoon. Comparable trends were observed in the OL system. Significant differences in TS, VS, moisture content, pH, electrical conductivity, and major cations (Na⁺, K⁺, Ca²⁺) occurred between CL and OL systems and among treatment stages. The secondary lagoon further enhanced microbial and solids reductions in both systems. Overall, the findings show that CL systems provide superior pathogen reduction and support biogas recovery, whereas OL systems demonstrate stronger VS stabilization. These results offer practical, field-based insights to inform improved manure management and pathogen mitigation strategies for commercial dairy operations. Full article

Pixian Doubanjiang (PXDB) is a traditional Chinese fermented condiment whose characteristic aroma and taste are strongly influenced by fermentation conditions. This study aimed to systematically compare the flavor profiles of PXDB produced via traditional open fermentation (TOF) and industrial closed fermentation (ICF), aiming to elucidate the chemical basis of sensory divergence and provide scientific support for industrial process optimization. In this study, PXDB samples were evaluated using sensory evaluation, GC-IMS, ¹H-NMR metabolomics, and multivariate statistical analysis. Sensory evaluation revealed that ICF exhibited a stronger soy sauce-like aroma, alcohol note, and umami intensity, whereas TOF and ICF showed comparable sweetness, sourness, chili-like aroma, and roasted aroma. GC-IMS putatively identified 126 volatile compounds, and multivariate analyses demonstrated a clear separation between the two fermentation modes. Based on combined criteria of VIP > 1, FDR-adjusted p < 0.05, and |fold change| > 2, 35 differential volatile compounds were identified. ICF was characterized by higher levels of esters, particularly ethyl esters, and selected ketones, while TOF showed enrichment of higher alcohols, terpenes, and sulfur compounds. ¹H-NMR analysis identified 54 non-volatile metabolites, of which 16 differed significantly between TOF and ICF, mainly involving amino acids, organic acids, and carbohydrates. Pathway analysis highlighted branched-chain amino acid and glutamate-related metabolism as key contributors to flavor divergence. Correlation analysis further revealed that soy sauce-like aroma and umami perception were strongly associated with amino acid-derived metabolites, esters, sulfur-containing compounds, and branched-chain aldehydes, highlighting the coordinated contribution of volatile and non-volatile compounds to flavor differentiation. Overall, fermentation mode was found to reshape PXDB flavor through coordinated modulation of volatile and non-volatile metabolism, providing experimental insight for improving industrial fermentation quality. Full article

Hypoxic training is widely used to enhance endurance performance, yet its application in combat sports such as judo is poorly understood. This study explored (1) hypoxic training practices, (2) perceptions, and (3) educational pathways among judo athletes and performance staff (coaches/practitioners). A total of 173 judo athletes and 39 performance staff completed an online questionnaire covering participant characteristics, hypoxic practices, education, and perceptions. Closed-ended responses were analysed using frequency statistics, and open-ended responses using thematic analysis. Hypoxic training was not widely used, with most respondents reporting no engagement. Among participants currently using hypoxic training, the primary aim was to enhance sea-level performance (13.7%), with limited use for altitude competition (8.5%). Natural altitude was the most common modality, with 7.1% respondents currently using it, typically at ≤1500 m. Only 20.8% of participants reported receiving or delivering education on hypoxic training. Perceptions were mixed, with 38.7% agreeing it benefits judo performance, although agreement was higher among performance staff than athletes. Thematic analysis identified perceived benefits (e.g., time-efficient fitness gains) and drawbacks (e.g., cost, access, and scheduling constraints). Hypoxic training is not a common practice in judo, but amongst some respondents it is perceived as potentially beneficial; these perceptions should not be interpreted as evidence of effectiveness. Its use is primarily oriented towards improving sea-level performance, and current knowledge appears largely informal. Greater sport-specific guidance and education may support more informed application in practice. Full article

Existing approaches for admissibility analysis of T-S fuzzy descriptor time delay systems fail to balance conservatism reduction and computational complexity. This paper proposes a low-conservatism analysis and stabilization method based on the symmetric Lyapunov–Krasovskii (L-K) functional. By exploiting the boundedness of membership function derivatives, and combining Jensen’s integral inequality with auxiliary slack matrices to achieve tight bounding of nonlinear terms, we derive an admissibility criterion for open-loop systems with significantly reduced conservatism. A well-suited L-K functional is constructed targeting the structural characteristics of fuzzy singular matrices $E_{\xi }$, a state feedback controller is designed via the parallel distributed compensation (PDC) strategy, and solvable sufficient conditions for the admissibility of closed-loop systems are established. Numerical examples demonstrate that the maximum allowable delay upper bound obtained by the proposed method outperforms that of existing state-of-the-art approaches while balancing conservatism and computation cost and verifying the superiority of the proposed method. Full article

The transfer-matrix method is employed to investigate a spin-1/2 Ising chain under open and periodic boundary conditions. It is demonstrated that finite-size Ising chains with antiferromagnetic coupling may exhibit significantly distinct magnetic behavior under open and periodic boundary conditions. While the open Ising chains display intriguing magnetic features regardless of the system size, mainly due to a specific contribution of boundary spins, the magnetic behavior of closed Ising chains depends basically on the number of spins. The closed Ising chains with an odd number of spins are subject to a geometric spin frustration leading to an additional plateau in the magnetization curve, which is naturally absent in the closed Ising chains with an even number of spins. Despite different microscopic origins, the magnetization curves of open and closed Ising chains with an odd number of spins exhibit an identical intermediate plateau, with only small quantitative differences appearing at moderate temperatures, which means that a geometric spin frustration of odd-membered rings is somewhat similar to the effect of open boundaries. The magnetization curves of the open Ising chains with an even number of spins differ drastically from those of the closed Ising chains due to the presence of an additional intermediate magnetization plateau. Furthermore, the initial susceptibility, inverse initial susceptibility, and susceptibility–temperature product are examined in detail as functions of temperature. These magnetic response functions demonstrate that the Curie constant and Weiss temperature represent fundamental characteristics of the magnetic system that are independent of the choice of boundary conditions. Full article

Fusing spatial observations from sensors with heterogeneous error characteristics is a persistent challenge in geostatistics. Classical kriging assumes a Gaussian likelihood for all observations, an assumption that fails when sensors exhibit one-sided or asymmetric noise. We present a Variable Rank Kriging (VRK) formulation that supports per-observation heterogeneous likelihoods where each observation may define its own likelihood function, thus enabling principled fusion of sensors whose noise structures are significantly different in terms of distribution family and magnitude. Within this framework, we use the exponential (one-sided) likelihood as a case study to demonstrate the method and compare it with sampling-based numerical alternatives for general likelihoods without closed forms. A non-collocated RTK calibration workflow uses kriging predictions from a sparse high-accuracy reference to characterise sensor-specific likelihood parameters without requiring co-located paired observations. Synthetic 1-D and 2-D experiments show that correct per-point likelihood specification reduces RMSE by up to 92% (1-D) and 57% (2-D) relative to a misspecified Gaussian model while also eliminating systematic positive bias. A demonstration using NEON Airborne Observation Platform lidar data at Harvard Forest confirms these findings in a practical, real-world scenario. Across multiple subsamples of the lidar dataset, the exponential likelihood reduces vegetated-zone RMSE by $20.6\%$ (open zone: $18.6\%$) and mean absolute bias by $26.5\%$ relative to a heteroscedastic Gaussian baseline. The open-source vrk Python ($>=$3.10) package provides a reproducible implementation that can be applied to any spatial domain that requires multi-sensor spatial fusion with heterogeneous error structures. Full article

Engaging students in sustainability challenges is often easier in theory than in practice. This study examines first-year French undergraduates’ patterns of engagement with the TEDS module (Transition Ecologique pour un Développement Soutenable), a nationwide programme developed in France to promote ecological transition and sustainable development. Data were collected through an online questionnaire comprising 24 closed- and open-ended questions exploring students’ self-reported familiarity with, understanding of, concern about, and self-reported intentions to engage in sustainability-related actions, as well as perceived learning needs and background characteristics. Only 18 questions (143 items) were included in the present analysis, covering all dimensions except those related to the evaluation of the training programme. Results indicate that environmental concern is the factor most strongly associated with self-reported engagement intention, despite persistent gaps in conceptual understanding, particularly regarding the Anthropocene and alternative socio-economic models. Knowledge score and concern are structured hierarchically according to issue visibility, with climate change ranking highest. Engagement depends not only on concern but also on perceived opportunities for action, yet students struggle to identify concrete pathways. The absence of significant differences across gender and disciplines points to a strong generational convergence that reshapes the determinants of environmental engagement. Overall, the key challenge for sustainability education is linking systemic knowledge to concrete contexts of learning and everyday life. Full article

Slope stability in open-pit mining is not a static condition but evolves continuously as excavation progresses and geomechanical conditions change. In this study, an integrated approach combining ground-based radar monitoring, satellite-based InSAR time-series analysis, and numerical stability modeling was applied to evaluate slope behavior in a large-scale open-pit copper mine with complex geological and structural characteristics. Radar data revealed progressive and episodic deformation concentrated in specific slope sectors, while InSAR observations showed that deformation continued at lower rates after the main movement phase, providing a longer-term perspective of slope response. Stability analyses using limit equilibrium and finite element methods indicate that the slope operates close to a limit equilibrium condition, particularly under saturated scenarios where factors of safety approach critical levels and strain localization becomes more pronounced. The results show a clear link between observed deformation patterns and calculated stability conditions, with structural discontinuities and groundwater playing a dominant role in controlling slope behavior. Based on these findings, an integrated workflow is proposed that links monitoring data with stability assessment, enabling the identification of critical zones and supporting the evaluation of slope conditions during ongoing mining operations. This approach contributes to more reliable decision-making and supports safer and more sustainable open-pit mining practices. Full article

Koji production is a critical process that determines the flavor and quality of the final soy sauce product. However, the complex mechanisms underlying microbial metabolism and the evolution of the physicochemical environment still require further analysis. This study focuses on three parallel koji rooms in an industrialized koji fermentation process. This work tracked the dynamics of physicochemical indices, volatile flavor compounds, and microbial communities over a full 40 h cycle. Data integration and correlation analysis elucidated the close linkage between the microbial community, the fermentation environment, and flavor formation. Koji moisture declined gradually, with faster losses at later fermentation stages. This physiological dehydration arose from microbial metabolic heat, forced aeration and structural loosening of koji, not simple physical evaporation. System pH displayed a typical U-shaped trend across fermentation. Values dropped early, most likely driven by accumulating organic acids, before rising from mid to late fermentation. This pH rebound was tentatively attributed to ammonia release from proteolytic breakdown, which may neutralize acidic compounds. These observations cast doubt on the conventional assumption that organic acid levels may be reliably estimated solely from pH measurements. Physicochemical analysis showed continuous accumulation of amino acid nitrogen (0.6–0.9 g/100 g) and total acidity throughout fermentation. By contrast, reducing sugar concentrations differed across individual koji rooms, presumably owing to divergent microbial adaptation in early fermentation. A total of 77 common compounds were identified, among which 13 key odor-active compounds with OAV ≥ 1, such as 4-vinylguaiacol and 3-methylbutyraldehyde, constitute the characteristic flavor profile of soy sauce starter culture. High-throughput sequencing uncovered a distinct ecological pattern: eukaryotic communities, dominated by Aspergillus oryzae, converged under controlled regulation. While prokaryotic communities differentiated dynamically, driven by spatial heterogeneity in the semi-open fermentation environment. Spearman correlation analysis further indicated potential functional partitioning: high-abundance taxa (e.g., Aspergillus oryzae, Weissella) were predominantly associated with macromolecular substrate degradation, whereas rare low-abundance taxa (e.g., Alternaria) displayed significant correlations with the biosynthesis of key characteristic flavor compounds. This study clarifies the synergistic regulatory mechanisms linking physicochemical conditions, microbial metabolism, and flavor precursor formation during industrial koji production. The findings establish a scientific foundation for optimizing process parameters and achieving standardized quality control in soy sauce manufacturing. Full article

Potatoes are a crop of great importance for global food security, and their industrialization requires certain postharvest quality characteristics that are affected by cultivation practices. Unlike previous studies that focused on single agronomic factors or genotype effects, to increase knowledge, this work evaluates the interaction between planting method (bag vs. soil) and cultivation condition (greenhouse vs. open field) on postharvest and frying quality of the high-altitude variety ‘Diacol Capiro’. A completely randomized design was used with four treatments arranged in a 2 × 2 factorial layout, where the first factor was the planting method (in bags or in soil) and the second factor was the cultivation conditions (in a greenhouse or in an open field). Tubers grown in a greenhouse, especially with planting in bags, showed greater starch retention, higher firmness, lower soluble solids content, and less mass loss during storage. The starch content varied significantly among treatments, reaching a maximum of 6.9% after 35 days of storage. The specific gravity of the fried potatoes was higher in greenhouse-grown tubers (1.080) than in those planted in the open field (1.070), with values close to the industrial standard (>1.080). The skin luminosity decreased by 16.2% during storage, while the b* parameter of the flesh (yellow color) was higher in tubers from greenhouse planting. Overall, ‘Diacol Capiro’ tubers grown in a greenhouse with planting in bags showed better postharvest attributes and greater potential for frying quality. Full article

Upcycling biomass waste into value-added battery materials is crucial for sustainable energy storage. Here, we transform coffee grounds into high-performance hard carbon (HC) anodes for sodium-ion batteries (SIBs) via a synergistic pre-oxidation and acetylene chemical vapor deposition (CVD) strategy, which effectively reduces open pores and promotes structural stabilization. The resulting material exhibits features consistent with a closed-pore architecture. Pre-oxidation incorporates oxygen-containing functional groups that template accessible pores and expand the interlayer spacing during carbonization. Subsequent CVD covers surface pores and contributes to the stabilization of the pore structure. The optimized HC (COF300&1300@C) exhibits a balanced set of structural features, including a low specific surface area (2.1 m² g⁻¹), expanded interlayer distance (0.391 nm), and a well-regulated pore system with reduced surface area and controlled pore size. As a result, it delivers a reversible capacity of 298 mAh g⁻¹ with an ICE of 70%, and remarkable cycling stability (97% capacity retention after 500 cycles at 1C). This study elucidates the synergistic mechanism of pre-oxidation and CVD in reducing open pores and stabilizing the pore architecture, thereby yielding characteristics indicative of closed-pore behavior, and providing a novel and efficient approach for designing high-performance biomass-derived hard carbons for energy storage. Full article