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28 pages, 9666 KiB  
Article
An Efficient Path Planning Algorithm Based on Delaunay Triangular NavMesh for Off-Road Vehicle Navigation
by Ting Tian, Huijing Wu, Haitao Wei, Fang Wu and Jiandong Shang
World Electr. Veh. J. 2025, 16(7), 382; https://doi.org/10.3390/wevj16070382 - 7 Jul 2025
Viewed by 205
Abstract
Off-road path planning involves navigating vehicles through areas lacking established road networks, which is critical for emergency response in disaster events, but is limited by the complex geographical environments in natural conditions. How to model the vehicle’s off-road mobility effectively and represent environments [...] Read more.
Off-road path planning involves navigating vehicles through areas lacking established road networks, which is critical for emergency response in disaster events, but is limited by the complex geographical environments in natural conditions. How to model the vehicle’s off-road mobility effectively and represent environments is critical for efficient path planning in off-road environments. This paper proposed an improved A* path planning algorithm based on a Delaunay triangular NavMesh model with off-road environment representation. Firstly, a land cover off-road mobility model is constructed to determine the navigable regions by quantifying the mobility of different geographical factors. This model maps passable areas by considering factors such as slope, elevation, and vegetation density and utilizes morphological operations to minimize mapping noise. Secondly, a Delaunay triangular NavMesh model is established to represent off-road environments. This mesh leverages Delaunay triangulation’s empty circle and maximum-minimum angle properties, which accurately represent irregular obstacles without compromising computational efficiency. Finally, an improved A* path planning algorithm is developed to find the optimal off-road mobility path from a start point to an end point, and identify a path triangle chain with which to calculate the shortest path. The improved road-off path planning A* algorithm proposed in this paper, based on the Delaunay triangulation navigation mesh, uses the Euclidean distance between the midpoint of the input edge and the midpoint of the output edge as the cost function g(n), and the Euclidean distance between the centroids of the current triangle and the goal as the heuristic function h(n). Considering that the improved road-off path planning A* algorithm could identify a chain of path triangles for calculating the shortest path, the funnel algorithm was then introduced to transform the path planning problem into a dynamic geometric problem, iteratively approximating the optimal path by maintaining an evolving funnel region, obtaining a shortest path closer to the Euclidean shortest path. Research results indicate that the proposed algorithms yield optimal path-planning results in terms of both time and distance. The navigation mesh-based path planning algorithm saves 5~20% of path length than hexagonal and 8-directional grid algorithms used widely in previous research by using only 1~60% of the original data loading. In general, the path planning algorithm is based on a national-level navigation mesh model, validated at the national scale through four cases representing typical natural and social landscapes in China. Although the algorithms are currently constrained by the limited data accessibility reflecting real-time transportation status, these findings highlight the generalizability and efficiency of the proposed off-road path-planning algorithm, which is useful for path-planning solutions for emergency operations, wilderness adventures, and mineral exploration. Full article
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17 pages, 8187 KiB  
Article
Ground-Level Surface Reconstruction and Soil Volume Estimation in Construction Sites Using Marching Cubes Method
by Fattah Hanafi Sheikhha, Jaho Seo and Hanmin Lee
Appl. Sci. 2025, 15(13), 7595; https://doi.org/10.3390/app15137595 - 7 Jul 2025
Viewed by 160
Abstract
Accurate environmental sensing is pivotal for advancing automation in construction, particularly in autonomous excavation. Precise 3D representations of complex and dynamic site geometries is essential for obstacle detection, progress monitoring, and safe operation. However, existing sensing techniques often struggle with capturing irregular surfaces [...] Read more.
Accurate environmental sensing is pivotal for advancing automation in construction, particularly in autonomous excavation. Precise 3D representations of complex and dynamic site geometries is essential for obstacle detection, progress monitoring, and safe operation. However, existing sensing techniques often struggle with capturing irregular surfaces and incomplete data in real-time, leading to significant challenges in practical deployment. To address these gaps, we present a novel framework integrating curve approximation, surface reconstruction, and marching cubes algorithm to transform raw sensor data into a detailed and computationally efficient soil surface representation. Our approach improves site modeling accuracy, paving the way for reliable and efficient construction automation. This paper enhances sensory data quality using surface reconstruction techniques, followed by the marching cubes algorithm to generate an accurate and flexible 3D soil model. This model facilitates rapid estimation of soil volume, weight, and shape, offering an efficient approach for environmental analysis and decision-making in automated systems. Experimental validation demonstrated the effectiveness of the proposed method, achieving relative errors of 4.92% and 1.42% across two excavation cycles. Additionally, the marching cubes algorithm completed volume estimation in just 0.05 s, confirming the approach’s accuracy and suitability for real-time applications in dynamic construction environments. Full article
(This article belongs to the Section Applied Industrial Technologies)
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24 pages, 9035 KiB  
Article
MPN-RRT*: A New Method in 3D Urban Path Planning for UAV Integrating Deep Learning and Sampling Optimization
by Yue Zheng, Ang Li, Zihan Chen, Yapeng Wang, Xu Yang and Sio-Kei Im
Sensors 2025, 25(13), 4142; https://doi.org/10.3390/s25134142 - 2 Jul 2025
Viewed by 431
Abstract
The increasing deployment of unmanned aerial vehicles (UAVs) in complex urban environments necessitates efficient and reliable path planning algorithms. While traditional sampling-based methods such as Rapidly exploring Random Tree Star (RRT*) are widely adopted, their computational inefficiency and suboptimal path quality in intricate [...] Read more.
The increasing deployment of unmanned aerial vehicles (UAVs) in complex urban environments necessitates efficient and reliable path planning algorithms. While traditional sampling-based methods such as Rapidly exploring Random Tree Star (RRT*) are widely adopted, their computational inefficiency and suboptimal path quality in intricate 3D spaces remain significant challenges. This study proposes a novel framework (MPN-RRT*) that integrates Motion Planning Networks (MPNet) with RRT* to enhance UAV navigation in 3D urban maps. A key innovation lies in reducing computational complexity through dimensionality reduction, where 3D urban terrains are sliced into 2D maze representations while preserving critical obstacle information. Transfer learning is applied to adapt a pre-trained MPNet model to the simplified maps, enabling intelligent sampling that guides RRT* toward promising regions and reduces redundant exploration. Extensive MATLAB simulations validate the framework’s efficacy across two distinct 3D environments: a sparse 200 × 200 × 200 map and a dense 800 × 800 × 200 map with no-fly zones. Compared to conventional RRT*, the MPN-RRT* achieves a 47.8% reduction in planning time (from 89.58 s to 46.77 s) and a 19.8% shorter path length (from 476.23 m to 381.76 m) in simpler environments, alongside smoother trajectories quantified by a 91.2% reduction in average acceleration (from 14.67 m/s² to 1.29 m/s²). In complex scenarios, the hybrid method maintains superior performance, reducing flight time by 14.2% and path length by 13.9% compared to RRT*. These results demonstrate that the integration of deep learning with sampling-based planning significantly enhances computational efficiency, path optimality, and smoothness, addressing critical limitations in UAV navigation for urban applications. The study underscores the potential of data-driven approaches to augment classical algorithms, providing a scalable solution for real-time autonomous systems operating in high-dimensional dynamic environments. Full article
(This article belongs to the Special Issue Recent Advances in UAV Communications and Networks)
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23 pages, 3344 KiB  
Article
Trajectory Optimization with Dynamic Drivable Corridor-Based Collision Avoidance
by Weijie Wang, Tantan Zhang, Zihan Song and Haipeng Liu
Appl. Sci. 2025, 15(13), 7051; https://doi.org/10.3390/app15137051 - 23 Jun 2025
Viewed by 249
Abstract
Trajectory planning for autonomous vehicles is essential for ensuring driving safety, passenger comfort, and operational efficiency. Collision avoidance constraints introduce significant computational complexity due to their inherent non-convex and nonlinear characteristics. Previous research has proposed the drivable corridor (DC) method, which transforms complex [...] Read more.
Trajectory planning for autonomous vehicles is essential for ensuring driving safety, passenger comfort, and operational efficiency. Collision avoidance constraints introduce significant computational complexity due to their inherent non-convex and nonlinear characteristics. Previous research has proposed the drivable corridor (DC) method, which transforms complex collision avoidance constraints into linear inequalities by constructing time-varying rectangular corridors within the spatiotemporal domains, thereby enhancing optimization efficiency. However, the DC construction process involves repetitive collision detection, leading to an increased computational burden. To address this limitation, this study proposes a novel approach that integrates grid-based obstacle representation with dynamic grid merging to accelerate collision detection and dynamically constructs the DC by adaptively adjusting the expansion strategies according to available spatial dimensions. The feasibility and effectiveness of the proposed method are validated through simulation-based evaluations conducted over 100 representative scenarios characterized by diverse and unstructured environmental configurations. The simulation results indicate that, with appropriately selected grid resolutions, the proposed approach achieves up to a 60% reduction in trajectory planning time compared to conventional DC-based planners while maintaining robust performance in complex environments. Full article
(This article belongs to the Special Issue Advancements in Motion Planning and Control for Autonomous Vehicles)
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20 pages, 4391 KiB  
Article
GDS-YOLOv7: A High-Performance Model for Water-Surface Obstacle Detection Using Optimized Receptive Field and Attention Mechanisms
by Xu Yang, Lei Huang, Fuyang Ke, Chao Liu, Ruixue Yang and Shicheng Xie
ISPRS Int. J. Geo-Inf. 2025, 14(7), 238; https://doi.org/10.3390/ijgi14070238 - 23 Jun 2025
Viewed by 275
Abstract
Unmanned ships, equipped with self-navigation and image processing capabilities, are progressively expanding their applications in fields such as mining, fisheries, and marine environments. Along with this development, issues concerning waterborne traffic safety are gradually emerging. To address the challenges of navigation and obstacle [...] Read more.
Unmanned ships, equipped with self-navigation and image processing capabilities, are progressively expanding their applications in fields such as mining, fisheries, and marine environments. Along with this development, issues concerning waterborne traffic safety are gradually emerging. To address the challenges of navigation and obstacle detection on the water’s surface, this paper presents CDS-YOLOv7, an enhanced obstacle-detection framework for aquatic environments, architecturally evolved from YOLOv7. The proposed system implements three key innovations: (1) Architectural optimization through replacement of the Spatial Pyramid Pooling Cross Stage Partial Connections (SPPCSPC) module with GhostSPPCSPC for expanded receptive field representation. (2) Integration of a parameter-free attention mechanism (SimAM) with refined pooling configurations to boost multi-scale detection sensitivity, and (3) Strategic deployment of depthwise separable convolutions (DSC) to reduce computational complexity while maintaining detection fidelity. Furthermore, we develop a Spatial–Channel Synergetic Attention (SCSA) mechanism to counteract feature degradation in convolutional operations, embedding this module within the Extended Effective Long-Range Aggregation Network (E-ELAN) network to enhance contextual awareness. Experimental results reveal the model’s superiority over baseline YOLOv7, achieving 4.9% mean average precision@0.5 (mAP@0.5), +4.3% precision (P), and +6.9% recall (R) alongside a 22.8% reduction in Giga Floating-point Operations Per Second (GFLOPS). Full article
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21 pages, 5449 KiB  
Article
ELD-YOLO: A Lightweight Framework for Detecting Occluded Mandarin Fruits in Plant Research
by Xianyao Wang, Yutong Huang, Siyu Wei, Weize Xu, Xiangsen Zhu, Jiong Mu and Xiaoyan Chen
Plants 2025, 14(11), 1729; https://doi.org/10.3390/plants14111729 - 5 Jun 2025
Viewed by 476
Abstract
Mandarin fruit detection provides crucial technical support for yield prediction and the precise identification and harvesting of mandarin fruits. However, challenges such as occlusion from leaves or branches, the presence of small or partially visible fruits, and limitations in model efficiency pose significant [...] Read more.
Mandarin fruit detection provides crucial technical support for yield prediction and the precise identification and harvesting of mandarin fruits. However, challenges such as occlusion from leaves or branches, the presence of small or partially visible fruits, and limitations in model efficiency pose significant obstacles in a complex orchard environment. To tackle these issues, we propose ELD-YOLO, a lightweight detection framework designed to enhance edge detail preservation and improve the detection of small and occluded fruits. Our method incorporates edge-aware processing to strengthen feature representation, introduces a streamlined detection head that balances accuracy with computational cost, and employs an adaptive upsampling strategy to minimize information loss during feature scaling. Experiments on a mandarin fruit dataset show that ELD-YOLO achieves a precision of 89.7%, a recall of 83.7%, an mAP@50 of 92.1%, and an mAP@50:95 of 68.6% while reducing the parameter count by 15.4% compared with the baseline. These results demonstrate that ELD-YOLO provides an effective and efficient solution for fruit detection in complex orchard scenarios. Full article
(This article belongs to the Special Issue Advances in Artificial Intelligence for Plant Research)
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21 pages, 29616 KiB  
Article
CSEANet: Cross-Stage Enhanced Aggregation Network for Detecting Surface Bolt Defects in Railway Steel Truss Bridges
by Yichao Chen, Yifan Sun, Ziheng Qin, Zhipeng Wang and Yixuan Geng
Sensors 2025, 25(11), 3500; https://doi.org/10.3390/s25113500 - 31 May 2025
Viewed by 464
Abstract
The accurate detection of surface bolt defects in railway steel truss bridges plays a vital role in maintaining structural integrity. Conventional manual inspection techniques require extensive labor and introduce subjective assessments, frequently yielding variable results across inspections. While UAV-based approaches have recently been [...] Read more.
The accurate detection of surface bolt defects in railway steel truss bridges plays a vital role in maintaining structural integrity. Conventional manual inspection techniques require extensive labor and introduce subjective assessments, frequently yielding variable results across inspections. While UAV-based approaches have recently been developed, they still encounter significant technical obstacles, including small target recognition, background complexity, and computational limitations. To overcome these challenges, CSEANet is introduced—an improved YOLOv8-based framework tailored for bolt defect detection. Our approach introduces three innovations: (1) a sliding-window SAF preprocessing method that improves small target representation and reduces background noise, achieving a 0.404 mAP improvement compared with not using it; (2) a refined network architecture with BSBlock and MBConvBlock for efficient feature extraction with reduced redundancy; and (3) a novel BoltFusionFPN module to enhance multi-scale feature fusion. Experiments show that CSEANet achieves an mAP@50:95 of 0.952, confirming its suitability for UAV-based inspections in resource-constrained environments. This framework enables reliable, real-time bolt defect detection, supporting safer railway operations and infrastructure maintenance. Full article
(This article belongs to the Section Remote Sensors)
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21 pages, 5032 KiB  
Article
Spatio-Temporal Reinforcement Learning-Driven Ship Path Planning Method in Dynamic Time-Varying Environments: Research on Adaptive Decision-Making in Typhoon Scenarios
by Weizheng Wang, Fenghua Liu, Kai Cheng, Zuopeng Niu and Zhengwei He
Electronics 2025, 14(11), 2197; https://doi.org/10.3390/electronics14112197 - 28 May 2025
Viewed by 353
Abstract
In dynamic environments with continuous variability, such as those affected by typhoons, ship path planning must account for both navigational safety and the maneuvering characteristics of the vessel. However, current methods often struggle to accurately capture the continuous evolution of dynamic obstacles and [...] Read more.
In dynamic environments with continuous variability, such as those affected by typhoons, ship path planning must account for both navigational safety and the maneuvering characteristics of the vessel. However, current methods often struggle to accurately capture the continuous evolution of dynamic obstacles and generally lack adaptive exploration mechanisms. Consequently, the planned routes tend to be suboptimal or incompatible with the ship’s maneuvering constraints. To address this challenge, this study proposes a Space–Time Integrated Q-Learning (STIQ-Learning) algorithm for dynamic path planning under typhoon conditions. The algorithm is built upon the following key innovations: (1) Spatio-Temporal Environment Modeling: The hazardous area affected by the typhoon is decomposed into temporally and spatially dynamic obstacles. A grid-based spatio-temporal environment model is constructed by integrating forecast data on typhoon wind radii and wave heights. This enables a precise representation of the typhoon’s dynamic evolution process and the surrounding maritime risk environment. (2) Optimization of State Space and Reward Mechanism: A time dimension is incorporated to expand the state space, while a composite reward function is designed by combining three sub-reward terms: target proximity, trajectory smoothness, and heading correction. These components jointly guide the learning agent to generate navigation paths that are both safe and consistent with the maneuverability characteristics of the vessel. (3) Priority-Based Adaptive Exploration Strategy: A prioritized action selection mechanism is introduced based on collision feedback, and the exploration factor ϵ is dynamically adjusted throughout the learning process. This strategy enhances the efficiency of early exploration and effectively balances the trade-off between exploration and exploitation. Simulation experiments were conducted using real-world scenarios derived from Typhoons Pulasan and Gamei in 2024. The results demonstrate that in open-sea environments, the proposed STIQ-Learning algorithm achieves reductions in path length of 14.4% and 22.3% compared to the D* and Rapidly exploring Random Trees (RRT) algorithms, respectively. In more complex maritime environments featuring geographic constraints such as islands, STIQ-Learning reductions of 2.1%, 20.7%, and 10.6% relative to the DFQL, D*, and RRT algorithms, respectively. Furthermore, the proposed method consistently avoids the hazardous wind zones associated with typhoons throughout the entire planning process, while maintaining wave heights along the generated routes within the vessel’s safety limits. Full article
(This article belongs to the Section Computer Science & Engineering)
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19 pages, 14298 KiB  
Article
BETAV: A Unified BEV-Transformer and Bézier Optimization Framework for Jointly Optimized End-to-End Autonomous Driving
by Rui Zhao, Ziguo Chen, Yuze Fan, Fei Gao and Yuzhuo Men
Sensors 2025, 25(11), 3336; https://doi.org/10.3390/s25113336 - 26 May 2025
Viewed by 627
Abstract
End-to-end autonomous driving demands precise perception, robust motion planning, and efficient trajectory generation to navigate complex and dynamic environments. This paper proposes BETAV, a novel framework that addresses the persistent challenges of low 3D perception accuracy and suboptimal trajectory smoothness in autonomous driving [...] Read more.
End-to-end autonomous driving demands precise perception, robust motion planning, and efficient trajectory generation to navigate complex and dynamic environments. This paper proposes BETAV, a novel framework that addresses the persistent challenges of low 3D perception accuracy and suboptimal trajectory smoothness in autonomous driving systems through unified BEV-Transformer encoding and Bézier-optimized planning. By leveraging Vision Transformers (ViTs), our approach encodes multi-view camera data into a Bird’s Eye View (BEV) representation using a transformer architecture, capturing both spatial and temporal features to enhance scene understanding comprehensively. For motion planning, a Bézier curve-based planning decoder is proposed, offering a compact, continuous, and parameterized trajectory representation that inherently ensures motion smoothness, kinematic feasibility, and computational efficiency. Additionally, this paper introduces a set of constraints tailored to address vehicle kinematics, obstacle avoidance, and directional alignment, further enhancing trajectory accuracy and safety. Experimental evaluations on Nuscences benchmark datasets and simulations demonstrate that our framework achieves state-of-the-art performance in trajectory prediction and planning tasks, exhibiting superior robustness and generalization across diverse and challenging Bench2Drive driving scenarios. Full article
(This article belongs to the Section Vehicular Sensing)
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19 pages, 3691 KiB  
Article
ATDMNet: Multi-Head Agent Attention and Top-k Dynamic Mask for Camouflaged Object Detection
by Rui Fu, Yuehui Li, Chih-Cheng Chen, Yile Duan, Pengjian Yao and Kaixin Zhou
Sensors 2025, 25(10), 3001; https://doi.org/10.3390/s25103001 - 9 May 2025
Viewed by 566
Abstract
Camouflaged object detection (COD) encounters substantial difficulties owing to the visual resemblance between targets and their environments, together with discrepancies in multiscale representation of features. Current methodologies confront obstacles with feature distraction, modeling far-reaching dependencies, fusing multiple-scale details, and extracting boundary specifics. Consequently, [...] Read more.
Camouflaged object detection (COD) encounters substantial difficulties owing to the visual resemblance between targets and their environments, together with discrepancies in multiscale representation of features. Current methodologies confront obstacles with feature distraction, modeling far-reaching dependencies, fusing multiple-scale details, and extracting boundary specifics. Consequently, we propose ATDMNet, an amalgamated architecture combining CNN and transformer within a numerous phases feature extraction framework. ATDMNet employs Res2Net as the foundational encoder and incorporates two essential components: multi-head agent attention (MHA) and top-k dynamic mask (TDM). MHA improves local feature sensitivity and long-range dependency modeling by incorporating agent nodes and positional biases, whereas TDM boosts attention with top-k operations and multiscale dynamic methods. The decoding phase utilizes bilinear upsampling and sophisticated semantic guidance to enhance low-level characteristics, hence ensuring precise segmentation. Enhanced performance is achieved by deep supervision and a hybrid loss function. Experiments applying COD datasets (NC4K, COD10K, CAMO) demonstrate that ATDMNet establishes a new benchmark in both precision and efficiency. Full article
(This article belongs to the Special Issue Imaging and Sensing in Fiber Optics and Photonics: 2nd Edition)
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23 pages, 3914 KiB  
Article
Tensor-Based Uncoupled and Incomplete Multi-View Clustering
by Yapeng Liu, Wei Guo, Weiyu Li, Jingfeng Su, Qianlong Zhou and Shanshan Yu
Mathematics 2025, 13(9), 1516; https://doi.org/10.3390/math13091516 - 4 May 2025
Viewed by 389
Abstract
Multi-view clustering demonstrates strong performance in various real-world applications. However, real-world data often contain incomplete and uncoupled views. Missing views can lead to the loss of latent information, and uncoupled views create obstacles for cross-view learning. Existing methods rarely consider incomplete and uncoupled [...] Read more.
Multi-view clustering demonstrates strong performance in various real-world applications. However, real-world data often contain incomplete and uncoupled views. Missing views can lead to the loss of latent information, and uncoupled views create obstacles for cross-view learning. Existing methods rarely consider incomplete and uncoupled multi-view data simultaneously. To address these problems, a novel method called Tensor-based Uncoupled and Incomplete Multi-view Clustering (TUIMC) is proposed to effectively handle incomplete and uncoupled data. Specifically, the proposed method recovers missing samples in a low-dimensional feature space. Subsequently, the self-representation matrices are paired with the optimal views through permutation matrices. The coupled self-representation matrices are integrated into a third-order tensor to explore high-order information of multi-view data. An efficient algorithm is designed to solve the proposed model. Experimental results on five widely used benchmark datasets show that the proposed method exhibits superior clustering performance on incomplete and uncoupled multi-view data. Full article
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34 pages, 771 KiB  
Review
Polygenic Risk Scores for Personalized Cardiovascular Pharmacogenomics―A Scoping Review
by Aaryan Dwivedi, Jobanjit S. Phulka, Peyman Namdarimoghaddam and Zachary Laksman
Sci. Pharm. 2025, 93(2), 18; https://doi.org/10.3390/scipharm93020018 - 8 Apr 2025
Viewed by 2085
Abstract
Cardiovascular disease (CVD) is the leading cause of mortality worldwide, often involving a strong genetic background. Polygenic risk scores (PRSs) combine the cumulative effects of multiple genetic variants to quantify an individual’s susceptibility to CVD. Pharmacogenomics (PGx) can further personalize treatment by tailoring [...] Read more.
Cardiovascular disease (CVD) is the leading cause of mortality worldwide, often involving a strong genetic background. Polygenic risk scores (PRSs) combine the cumulative effects of multiple genetic variants to quantify an individual’s susceptibility to CVD. Pharmacogenomics (PGx) can further personalize treatment by tailoring medication choices to an individual’s genetic profile. Even with these potential benefits, the extent to which PRS can be integrated into the PGx of CVD remains unclear. Our review provides an overview of current evidence on the application of PRS in the PGx of CVD, examining clinical utility and limitations and providing directions for future research. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews protocol, we conducted a comprehensive literature search in PubMed, EMBASE, and the Web of Science. Studies investigating the relationship between PRS in predicting the efficacy, adverse effects, or cost-effectiveness of cardiovascular medications were selected. Of the 1894 articles identified, 32 met the inclusion criteria. These studies predominantly examined lipid-lowering therapies, antihypertensives, and antiplatelets, although other medication classes (e.g., rate-control drugs, ibuprofen/acetaminophen, diuretics, and antiarrhythmics) were also included. Our findings showed that PRS is most robustly validated in lipid-lowering therapies, especially statins, where studies reported that individuals with higher PRSs derived the greatest reduction in lipids while on statins. Studies analyzing antihypertensives, antiplatelets, and antiarrhythmic medications demonstrated more variable outcomes, though certain PRSs did identify subgroups with significantly improved response rates or a higher risk of adverse events. Though PRS was a strong tool in many cases, we found some key limitations in its applicability in research, such as the under-representation of non-European-ancestry cohorts in the examined studies and a lack of standardized outcome reporting. In conclusion, though PRS offers promise in improving the efficacy of PGx of CVD by enhancing the personalization of medication on an individual level, several obstacles, such as the need for including a broader ancestral diversity and more robust cost-effectiveness data remain. Future research must (i) prioritize validating PRS in ethnically diverse populations, (ii) refine PRS derivation methods to tailor them for drug response phenotypes, and (iii) establish clear and attainable guidelines for standardizing the reporting of outcomes. Full article
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18 pages, 3423 KiB  
Article
Voxel-Based Path Planning for Autonomous Vehicles in Parking Lots
by Zhaoyu Lin, Zhiyong Wang, Tailin Gong, Yingying Ma and Weidong Xie
ISPRS Int. J. Geo-Inf. 2025, 14(4), 147; https://doi.org/10.3390/ijgi14040147 - 28 Mar 2025
Viewed by 793
Abstract
With the development of autonomous driving technology, the application scenarios for mobile robots and unmanned vehicles are gradually expanding from simple structured environments to complex unstructured scenes. In unstructured three-dimensional spaces such as urban environments, traditional two-dimensional map construction and path planning techniques [...] Read more.
With the development of autonomous driving technology, the application scenarios for mobile robots and unmanned vehicles are gradually expanding from simple structured environments to complex unstructured scenes. In unstructured three-dimensional spaces such as urban environments, traditional two-dimensional map construction and path planning techniques struggle to effectively plan accurate paths. To address this, this paper proposes a method of constructing a map and planning a route based on three-dimensional spatial representation. This method utilizes point cloud semantic segmentation to extract navigable space information from environmental point cloud data and employs voxelization techniques to generate a voxel map. Building on this, the paper combines a variable search neighborhood A* algorithm with a road-edge-detection-based path adjustment to generate optimal paths between two points on the map, ensuring that the paths are both short and capable of effectively avoiding obstacles. Our experimental results in multi-story parking garages show that the proposed method effectively avoids narrow areas that are difficult for vehicles to pass through, increasing the average edge distance of the path by 83.3% and significantly enhancing path safety and feasibility. Full article
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28 pages, 4996 KiB  
Article
An Adaptive Obstacle Avoidance Model for Autonomous Robots Based on Dual-Coupling Grouped Aggregation and Transformer Optimization
by Yuhu Tang, Ying Bai and Qiang Chen
Sensors 2025, 25(6), 1839; https://doi.org/10.3390/s25061839 - 15 Mar 2025
Viewed by 1258
Abstract
Accurate obstacle recognition and avoidance are critical for ensuring the safety and operational efficiency of autonomous robots in dynamic and complex environments. Despite significant advances in deep-learning techniques in these areas, their adaptability in dynamic and complex environments remains a challenge. To address [...] Read more.
Accurate obstacle recognition and avoidance are critical for ensuring the safety and operational efficiency of autonomous robots in dynamic and complex environments. Despite significant advances in deep-learning techniques in these areas, their adaptability in dynamic and complex environments remains a challenge. To address these challenges, we propose an improved Transformer-based architecture, GAS-H-Trans. This approach uses a grouped aggregation strategy to improve the robot’s semantic understanding of the environment and enhance the accuracy of its obstacle avoidance strategy. This method employs a Transformer-based dual-coupling grouped aggregation strategy to optimize feature extraction and improve global feature representation, allowing the model to capture both local and long-range dependencies. The Harris hawk optimization (HHO) algorithm is used for hyperparameter tuning, further improving model performance. A key innovation of applying the GAS-H-Trans model to obstacle avoidance tasks is the implementation of a secondary precise image segmentation strategy. By placing observation points near critical obstacles, this strategy refines obstacle recognition, thus improving segmentation accuracy and flexibility in dynamic motion planning. The particle swarm optimization (PSO) algorithm is incorporated to optimize the attractive and repulsive gain coefficients of the artificial potential field (APF) methods. This approach mitigates local minima issues and enhances the global stability of obstacle avoidance. Comprehensive experiments are conducted using multiple publicly available datasets and the Unity3D virtual robot environment. The results show that GAS-H-Trans significantly outperforms existing baseline models in image segmentation tasks, achieving the highest mIoU (85.2%). In virtual environment obstacle avoidance tasks, the GAS-H-Trans + PSO-optimized APF framework achieves an impressive obstacle avoidance success rate of 93.6%. These results demonstrate that the proposed approach provides superior performance in dynamic motion planning, offering a promising solution for real-world autonomous navigation applications. Full article
(This article belongs to the Section Navigation and Positioning)
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22 pages, 23754 KiB  
Article
A Low-Latency Dynamic Object Detection Algorithm Fusing Depth and Events
by Duowen Chen, Liqi Zhou and Chi Guo
Drones 2025, 9(3), 211; https://doi.org/10.3390/drones9030211 - 15 Mar 2025
Viewed by 620
Abstract
Existing RGB image-based object detection methods achieve high accuracy when objects are static or in quasi-static conditions but demonstrate degraded performance with fast-moving objects due to motion blur artifacts. Moreover, state-of-the-art deep learning methods, which rely on RGB images as input, necessitate training [...] Read more.
Existing RGB image-based object detection methods achieve high accuracy when objects are static or in quasi-static conditions but demonstrate degraded performance with fast-moving objects due to motion blur artifacts. Moreover, state-of-the-art deep learning methods, which rely on RGB images as input, necessitate training and inference on high-performance graphics cards. These cards are not only bulky and power-hungry but also challenging to deploy on compact robotic platforms. Fortunately, the emergence of event cameras, inspired by biological vision, provides a promising solution to these limitations. These cameras offer low latency, minimal motion blur, and non-redundant outputs, making them well suited for dynamic obstacle detection. Building on these advantages, a novel methodology was developed through the fusion of events with depth to address the challenge of dynamic object detection. Initially, an adaptive temporal sampling window was implemented to selectively acquire event data and supplementary information, contingent upon the presence of objects within the visual field. Subsequently, a warping transformation was applied to the event data, effectively eliminating artifacts induced by ego-motion while preserving signals originating from moving objects. Following this preprocessing stage, the transformed event data were converted into an event queue representation, upon which denoising operations were performed. Ultimately, object detection was achieved through the application of image moment analysis to the processed event queue representation. The experimental results show that, compared with the current state-of-the-art methods, the proposed method has improved the detection speed by approximately 20% and the accuracy by approximately 5%. To substantiate real-world applicability, the authors implemented a complete obstacle avoidance pipeline, integrating our detector with planning modules and successfully deploying it on a custom-built quadrotor platform. Field tests confirm reliable avoidance of an obstacle approaching at approximately 8 m/s, thereby validating practical deployment potential. Full article
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