Search Results (239)

This exploratory study investigated the relationship between demographic, biological, and management-related factors and behavioral traits in 195 terrier-type dogs using the C-BARQ questionnaire. Participation in breed-specific cynological activities (ENCI working trials and aptitude tests) emerged as the most consistent factor: non-participation was associated with higher scores in owner-directed aggression (β = 0.17, p = 0.007), non-social fear (β = 0.34, p = 0.001), dog-directed fear (β = 0.36, p = 0.015), and attachment/attention-seeking (β = 0.32, p = 0.026), whereas participation was associated with increased chasing behavior (β = −0.60, p < 0.001). Neutered dogs showed higher non-social fear (β = 0.83, p < 0.001), touch sensitivity (β = 0.34, p = 0.012), and aggression toward conspecifics (β = 0.55, p = 0.004) and strangers (β = 0.32, p = 0.034). Age primarily influenced energy level (β = −0.09, p < 0.001) and dog-directed aggression (β = 0.05, p = 0.006) after FDR correction. Sex differences were modest, with males showing higher dog-directed aggression (β = −0.42, p = 0.004). Breed contributed to variability in selected domains, with the strongest effects observed for energy level and fear-related traits. Overall, these findings highlight participation in breed-specific activities and neuter status as key factors associated with behavior in terrier-type dogs. These associations are exploratory and require confirmation in future studies. Full article

Domestic cats (Felis catus) are ubiquitous companion animals that provide substantial psychological and social benefits to children and adults alike, but they also serve as reservoirs and vectors for a wide range of zoonotic pathogens. Close physical contact between cats and children, frequent use of shared environments such as homes, playgrounds, and sandboxes, and still-developing hygiene behaviours increase opportunities for exposure to protozoa, helminths, bacteria, fungi, and ectoparasite-borne agents. This review synthesizes current evidence on key feline-associated zoonoses of pediatric concern—including Toxoplasma gondii, Toxocara cati, Ancylostoma spp., Dipylidium caninum, Bartonella henselae, Salmonella enterica, Campylobacter jejuni, Pasteurella multocida, Microsporum canis, flea-borne Rickettsia species, and rabies—with emphasis on transmission routes, clinical manifestations, and risk modifiers in children, pregnant women, and immunocompromised individuals. Within a One Health framework, we also summarize global publication trends on feline zoonoses, discuss how urban cat ecology and management (including free-ranging cats in child-frequented environments) may shape pediatric risk, and outline practical prevention strategies centred on hygiene, veterinary care, and targeted education for caregivers and children. Full article

A 7-year-old, 38.3 kg, male neutered Labrador retriever presented to the Teaching Hospital for a consultation of Comprehensive Oral Health Assessment and Treatment. Nine months prior to the consultation, the patient presented to the ER service in the teaching hospital due to acute right facial swelling. To further evaluate the swelling in the ER, the patient was sedated by IV administration of dexmedetomidine and fentanyl, and ventricular premature contractions (VPCs) were confirmed. The facial swelling subsided afterward, but it recurred. Therefore, the dog was placed under general anesthesia to evaluate the recurrent facial swelling and undergo a dental procedure. After 55 min of discontinuation of isoflurane, no swallowing reflex was observed, making extubation not possible. Naloxone (0.01 mg/kg) was administered IV to reverse the effects of fentanyl. Within one minute of administering naloxone, the patient was extubated. However, the HR surged to 240 bpm, and sinus tachycardia was observed. Ninety minutes after naloxone IV, the HR was 105 bpm with normal sinus rhythm, gradually approaching the pre-anesthesia HR level (110 bpm). Veterinarians should recognize that administration of naloxone could induce arrhythmias. Therefore, continuous monitoring of ECG, pulse, and blood pressure is imperative when administering naloxone. Full article

Jujube (Ziziphus jujuba Mill.) is a widely consumed fruit in East Asia, yet its sharp-ended pits pose a high risk of gastrointestinal perforation in humans. While well-documented in human medicine, jujube pit ingestion in dogs has not previously been reported in the veterinary literature. This report describes a 15-year-old neutered male Maltese dog that presented with anorexia and lethargy five days after accidentally ingesting whole jujubes. Abdominal radiographs identified multiple intraluminal gastric foreign bodies demonstrating a distinctive, orientation-dependent sign: circular (transverse) or spindle-shaped (sagittal) opacities featuring a characteristic central longitudinal stripe. Although abdominal ultrasonography was limited in this specific case due to severe acoustic shadowing from localized gastric gas, the unique radiographic marker provided a reliable diagnostic clue before surgical confirmation. A gastrotomy was performed to successfully retrieve six intact, sharp-pointed pits, and the dog recovered uneventfully. To the authors’ knowledge, as the first report to describe the clinical progression and specific radiographic characteristics of jujube pits in a dog, this case highlights the central longitudinal stripe as a diagnostic clue. This marker facilitates the differentiation of jujube pits from other foreign bodies on plain radiographs, allowing for timely surgical intervention to prevent catastrophic complications. Full article

French Bulldogs are one of the most popular companion dog breeds worldwide, yet breed-specific behavioral data remain limited. This study aimed to characterize the behavioral profile of French Bulldogs in Italy using the Canine Behavioral Assessment and Research Questionnaire (C-BARQ) and to explore the relationships among sex, neuter status, coat color, and behavioral traits. An online survey was completed by 206 owners of French Bulldogs aged one year or older residing in Italy. Behavioral items were analyzed using ordinal logistic regression with sex, neuter status, and coat color as simultaneous predictors. French Bulldogs showed low aggression and fear-related behaviors, high attachment and attention-seeking tendencies, and moderate excitability and trainability. Sex was the most consistently associated predictor (17 items), with females showing lower odds for sexually dimorphic, fear-related, excitability, and separation-related behaviors. Neuter status showed limited, behavior-specific associations (4 items) involving leash-pulling, separation-related behaviors, and play-related excitability. Coat color was associated with ten behavioral items, including coprophagia, food stealing, hyperactivity, and submissive urination. Most pseudo-R² values were low (range: 0.009–0.059), reflecting the multifactorial nature of canine behavior. These findings offer a preliminary behavioral characterization of French Bulldogs in Italy and suggest that sex, neuter status, and coat color represent relevant sources of within-breed variation, warranting further research. Full article

Background: Free-roaming cats in Australian cities contribute to wildlife impacts, community concerns, and high shelter intake. We used an observational pre–post evaluation study design of a targeted cat desexing program (“StrayCare Metro”) delivered with councils and community partners in four local government areas (LGAs) of Greater Sydney (2022–2024). Methods: Program records documented cat enrolments and services; council and state databases supplied annual shelter intake, euthanasia, and cat-related complaints; and transect drives in two LGAs (2021 and 2024) estimated cat encounter rates and population density. The analysis did not include control LGAs. Results: The program desexed 1225 cats; among enrolled cats not already microchipped, 72% received a microchip and 28% declined despite this being offered for free. Compared with pre-program baselines, annual council shelter intake decreased by 49–73% within LGAs (61% overall), with concurrent reductions in euthanasia. Cat-related complaints declined in three LGAs (47–64%) but increased in one. Transect drives indicated substantial declines in cat encounter rates in Blue Mountains (51%) and Campbelltown (35%) and lower density estimates in both surveyed LGAs. Conclusions: A collaborative targeted desexing approach was associated with large reductions in council pound intake, euthanasia, and, in most areas, nuisance complaints, alongside independent indications of reduced free-roaming cat density. Full article

In search of a non-surgical alternative for male animal sterilization, this study investigated the use of gold-coated maghemite nanoparticles (γ-Fe₂O₃@Au) functionalized with citrate to produce testicular photohyperthermia (PHT). Wistar rats received an intratesticular injection of the fluid containing the nanoparticles (150 µL/testicle) followed by testicular irradiation with an LED light (808 nm). Testicular temperature was maintained at ~45 °C for 15 min. The results demonstrated a significant reduction in testicular volume and weight and sperm motility and normal morphology in PHT-treated animals, together with histopathological degeneration of seminiferous tubules. No treatment-related side effects or signs of systemic toxicity were observed. The biodistribution of the gold (Au) and iron (Fe) from the nanoparticles showed that the testes were the primary site of nanoparticle accumulation until day 56 post-treatment with possible renal excretion of Au. These findings support the prospect of testicular PHT mediated by γ-Fe₂O₃@Au nanoparticles as a neutering method for male animals. Full article

Domestic dogs show substantial behavioral variability shaped by genetic, biological, and environmental factors. Although breed-specific behavioral profiles are documented, associations between coat color and behavior within individual breeds remain poorly understood. This preliminary study characterized the behavioral profile of Australian Shepherd dogs and exploratorily investigated associations between behavior, coat color, sex, and neuter status using the validated Italian C-BARQ. A total of 215 Australian Shepherds aged 1–8.5 years were included; behavioral responses were analyzed using ordinal logistic regression with sex, neuter status, and coat color as predictors. Overall, Australian Shepherds showed high trainability and low aggression and fear toward humans. Sex emerged as the most consistent predictor: females showed lower odds of high-intensity responses in attachment- and excitability-related behaviors (OR ~0.44–0.56), with context-dependent differences in dog-directed and environmental responses. Neuter status was selectively associated with increased fear-related reactions to noise and stranger approaches (OR ~1.9–2.2) and reduced restlessness during separation (OR ~0.45). Coat color was not associated with generalized behavioral tendencies; item-level exploratory analyses revealed only a limited number of suggestive, context-specific associations in merle-coated dogs, and most analyses did not yield significant effects. All coat-color findings should be regarded as preliminary and hypothesis-generating. These results underscore the context-dependent nature of behavioral variation in Australian Shepherds and highlight the need for confirmatory studies with larger, coat-color-stratified samples. Full article

Owned house cats negatively affect wildlife when roaming outdoors, yet it remains unclear whether their movements are determined by selection for specific land cover types. We GPS-tracked 49 neutered, owned cats with daily outdoor access in a Mediterranean habitat, monitoring each for seven days. For each cat, we created a detailed, fine-scale land cover map from near-contemporaneous aerial imagery. We delineated each cat’s home range and compared its land cover composition to that of an equal-area circle centered on the median x and y coordinates of GPS fixes, representing directionally unbiased (isotropic) roaming. Home ranges were small (mean 0.85 ± 0.06 ha; median 0.73 ha; approximately 50 m radius), and cats whose ranges included nearby natural or semi-natural open areas had larger home ranges than cats in urban environments. Home range size was not affected by sex or season and decreased with age. Despite detailed, accurate mapping, no land cover class was found to be over- or under-represented within cat home ranges relative to the null expectation. These results, although limited to harness-tolerant cats, suggest that owned cats in our study area do not preferentially select specific land covers when roaming outdoors. Full article

An association between periodontal disease and comorbid disorders, including gastrointestinal signs, has been reported in cats and investigated in humans, where a bidirectional relationship between oral and gastrointestinal microbiomes exists. A 5-year-old neutered female domestic shorthair cat was presented with a 2-year history of small-bowel diarrhoea. The cat’s appetite was reduced, and coat quality had deteriorated. On examination, the cat was found to have periodontal disease affecting multiple teeth and a matted coat. Biochemistry revealed mild hyperproteinaemia, haematology was unremarkable, cobalamin was normal, folate was elevated, and retroviral testing was negative. Abdominal ultrasound showed diffuse muscularis thickening without other abnormalities, and dental examination and radiography revealed missing teeth, a root remnant, stage 4 periodontal disease, and tooth resorption. Multiple extractions were performed, and multimodal analgesia was provided, including locoregional dental blocks. The cat’s appetite, body condition, energy levels, and coat quality improved after the procedure, and the diarrhoea completely resolved within a month of the procedure without any changes in diet, physical, social environment, or the use of any medications, and did not recur during the following 7 months. This case illustrates the potential role of periodontal disease in the development of gastrointestinal disease and the benefits outside the oral cavity of managing dental disease in cats. Full article

Despite the global increase in cat ownership, some cats exhibit owner-directed aggression, resulting in caregiver injury, infection, and anxiety. Severe cases are commonly treated with selective serotonin reuptake inhibitors such as fluoxetine; however, adverse effects, particularly transient anorexia, often discourage treatment initiation. Cannabidiol (CBD), a natural compound with reported anxiolytic properties and minimal anorexic effects, may represent an alternative therapy. This study aimed to characterise owner-directed feline aggression in Thailand, identify associated factors, and compare the efficacy of CBD with fluoxetine. Most caregivers were females aged 20–40 years, and most cats were neutered mixed-breeds aged 1–6 years living indoors in multi-human and multi-cat households. For demographic variables, only human–cat interactions (e.g., petting) were significantly associated with aggression. Handling-induced aggression was universal, with grooming as the most common trigger (56%). In a single-blind, 4–8-week trial, 100 cats were randomly assigned to control, CBD 1 mg/kg/day, CBD 2 mg/kg/day, fluoxetine 0.5–1 mg/kg/day, or combined CBD and fluoxetine. Aggression scores decreased significantly in all treatment groups compared with control (p < 0.05), with no differences among active treatments. CBD at 1 mg/kg/day showed efficacy comparable to fluoxetine without anorexic effects. Full article

Uriniferous perinephric pseudocysts (PNPs) are a rare condition in cats, primarily managed by nephrectomy to eliminate persistent urinary leakage. Organ preservation is critical in cases with solitary kidneys. This report describes a cat with congenital absence of the right kidney that developed a uriniferous PNP secondary to abnormal communication between the calyceal diverticulum and subcapsular space. A 6-year-and-11-month-old neutered male Ragdoll cat presented with abdominal distension and lethargy. Ultrasonography revealed an extensive subcapsular perinephric fluid and a cystic lesion adjacent to the renal pelvis. Contrast-enhanced computed tomography with excretory urography directly demonstrated the time-dependent passage of contrast medium from the renal pelvis into the calyceal diverticulum and subsequent leakage into the subcapsular space, allowing precise identification of the renal leakage pathway. Based on these findings, an operation was performed using a non-vascularized free omental plug inserted into the diverticular opening and secured using capsular sutures. Postoperative drainage resolved rapidly, renal function normalized, and no recurrence was detected during long-term follow-up of up to 465 days. To the best of our knowledge, this is the first report to describe an organ-sparing surgical approach that directly addresses the renal leakage pathway in feline uriniferous PNPs. Full article

Brachycephalic dogs commonly suffer from breathing difficulties and other chronic health problems, yet strong consumer demand is widely reported. Whether the popularity of brachycephalic breeds persists across different contexts is largely untested. Census data from 1,510,085 canine consultations conducted at a single veterinary hospital from 2004 to 2023 in Hong Kong were collected and analysed. Individual dogs (n = 96,777) were counted once, in the first year of presentation. Males (53.5% to 57.7%) and purebreds (86.2% to 91.2%) predominated each year. Neutered dogs increased from 52% to 70% annually. Poodles were the most popular breed from 2009. Brachycephalic breeds, collectively, declined progressively from 36.3% to 15.4% of the annual population. This trend was exaggerated in dogs < 1-year-old (27.4% to 11.7%). Absolute numbers of common brachycephalic breeds declined, except for French Bulldogs and Pugs. A historical cohort study was conducted with a subset of the data (2016–2023) to investigate the hypothesis that veterinary service use would be higher in brachycephalic breeds compared with other groups. The hypothesis was proven. Relative demand for brachycephalic breeds in Hong Kong is decreasing, with the exception of French Bulldogs and Pugs. Investigating drivers of these observations will inform behaviour change strategies, and facilitate comparisons across different regions. Full article

Canine mammary tumours often present as multiple synchronous nodules, necessitating decisions regarding staging intensity and surgical planning prior to histology. We developed two preoperative nodule-level prediction models using only the medical history and physical examination of client-owned bitches with mammary disease, which were staged using the WHO-modified TNM system with a M0 classification (no distant metastasis) at the time of presentation. This retrospective study analysed 286 surgically excised mammary nodules from 92 dogs managed under a standardised mammary oncology protocol; those with inflammatory mammary carcinoma or distant metastasis were excluded. The outcomes were (i) malignant versus benign/non-neoplastic histology (for all nodules) and (ii) intermediate/high histologic grade (II–III versus I) among carcinomas. Separate multivariable Firth penalised logistic regression models accounted for within-dog clustering with dog-level bootstrap internal validation. Multiple imputation was used in a sensitivity analysis for missingness in the detection-to-surgery interval. Malignancy was confirmed in 87/286 (30.4%) of the nodules (86 carcinomas), including 35/87 (40.2%) that measured less than 1 cm. Among complete cases (153 nodules), malignancy was associated with age at neutering, maximum tumour diameter, owner-reported rapid growth and a detection-to-surgery interval of more than 3.5 months (an exploratory ROC-derived threshold) with good discrimination (area under the curve (AUC) 0.805; optimism-corrected 0.799) and acceptable calibration. Among carcinomas (83 specimen), previous mammary tumours, bloody nipple discharge and fewer synchronous nodules were associated with intermediate/high malignancy grade (AUC 0.859). Sensitivity analyses yielded directionally consistent estimates. Routinely available clinical information may provide interpretable preoperative risk stratification to support staging and surgical planning, pending external validation. Full article

In Australian Cattle Dogs (AUCDs), cystinuria was reported to be an autosomal dominant trait caused by a 6 bp deletion in the SLC3A1 gene (type II-A). Here we report an androgen association in this breed. A family of 11 adult AUCDs (five intact and one neutered male and five females) was genotyped for the SLC3A1 c.1095_1100del variant, and urine was examined for concentrations of cystine, ornithine, lysine, and arginine (COLA). Among this family, three males and five females tested heterozygous for the mutation, while all other AUCDs were homozygous for the wild-type allele. The two heterozygous intact males had severe COLA-uria, which decreased markedly after castration. Neither the third heterozygous male with a history of cystine calculi but already castrated nor the five heterozygous females exhibited increased COLA-uria. Heterozygosity for the 6 bp deletion in the SLC3A1 gene was associated with cystinuria in intact male AUCDs, but not in females. Castration of the heterozygous males reduced the cystinuria. Either the type II-A cystinuria in the AUCDs is an androgen-associated dominant trait, or this family also has another type III (androgen-dependent) cystinuria. Larger surveys are needed to further define the type(s) of cystinuria and effects of castration in AUCDs. Full article