Search Results (236)

Elevated extracellular potassium (K⁺) in the tumor microenvironment (TME) of breast and other cancers is increasingly recognized as a critical factor influencing tumor progression and immune suppression. Current methods for noninvasive mapping of the potassium distribution in tumors are limited. Here, we employed photoacoustic chemical imaging (PACI) with a solvatochromic dye-based, potassium-sensitive nanoprobe (SDKNP) to quantitatively visualize extracellular potassium levels in an orthotopic metaplastic breast cancer mouse model, Ccn6-KO. Tumors of three distinct sizes (5 mm, 10 mm, and 20 mm) were imaged using multi-wavelength photoacoustic imaging at five laser wavelengths (560, 576, 584, 605, and 625 nm). Potassium concentration maps derived from spectral unmixing of the photoacoustic images at the five laser wavelengths revealed significantly increased potassium levels in larger tumors, confirmed independently by inductively coupled plasma mass spectrometry (ICP-MS). The PACI results matched ICP-MS measurements, validating PACI as a robust, noninvasive imaging modality for potassium mapping in tumors in vivo. This work establishes PACI as a promising tool for studying the chemical properties of the TME and provides a foundation for future studies evaluating the immunotherapy response through ionic biomarker imaging. Full article

We report a passively Q-switched self-Raman laser using a dual-end composite c-cut Nd:YVO₄ crystal, which generates switchable visible emissions at 533 nm, 560 nm, and 589 nm. A Cr⁴⁺:YAG/YAG composite crystal served the role of a saturable absorber to achieve passive Q-switching. An angle-tuned BBO crystal was used to achieve the frequency mixing between the first-tokes wave and the fundamental wave. At an incident pump power of 9.5 W, the maximum average output powers were 425 mW for the 589 nm yellow laser, 193 mW for the 560 nm lime laser, and 605 mW for the 533 nm green laser, with corresponding pulse widths of approximately 3.8, 3.6, and 35.1 ns, respectively. This result shows that a passive Q-switching operation with self-Raman crystals presents a promising approach for compact multi-wavelength pulse laser sources. Full article

A continuous-wave (CW) orthogonally polarized single-wavelength red laser (OPSRL) at 698 nm with a tunable power ratio within a wide range between the two polarized components was demonstrated using two Pr³⁺:LiLuF₄ (Pr:LLF) crystals for the first time. Through control of the waist location of the pump beam in the active media, the output power ratio of the two polarized components of the OPSRL could be adjusted. Under pumping by a 20 W, 444 nm InGaN laser diode (LD), a maximum total output power of 4.12 W was achieved with equal powers for both polarized components, corresponding to an optical conversion efficiency of 23.8% relative to the absorbed pump power. Moreover, by a type-II critical phase-matched (CPM) BBO crystal, a CW ultraviolet (UV) second-harmonic generation (SHG) at 349 nm was also obtained with a maximum output power of 723 mW. OPSRLs can penetrate deep tissues and demonstrate polarization-controlled interactions, and are used in bio-sensing and industrial cutting with minimal thermal distortion, etc. The dual-polarized capability of OPSRLs also supports multi-channel imaging and high-speed interferometry. Full article

We present and demonstrate a highly birefringent fiber Bragg grating (Hi-Bi FBG) that was fabricated using a femtosecond laser to induce a sawtooth stress region near the FBG. The FBG is fabricated with a femtosecond laser point-by-point method, while the sawtooth stress region is generated in fiber cladding using the femtosecond laser along a sawtooth path. This sawtooth stressor can introduce an anisotropic and asymmetric refractive index profile in the cross-section of the fiber, resulting in additional birefringence up to 2.97 × 10⁻⁴ along the axial direction of the FBG. The central wavelengths of the Hi-Bi FBG at the fast and slow axes exhibit different sensitivities to temperature and strain, allowing simultaneous measurement of the strain and temperature by tracking the resonant wavelength shifts in the two axes. The experimental results show that the temperature sensitivities of the fast and slow axes are 10.32 pm/°C and 10.42 pm/°C, while the strain sensitivities are 0.91 pm/µε and 0.99 pm/µε. The accuracy of this proposed sensor in measuring strain and temperature is estimated to be 2.2 µε and 0.2 °C. This approach addresses the issue of cross-sensitivity between temperature and strain and offers some advantages of low cost, compact size, and significant potential for advancements in practical multi-parameter sensing applications. Full article

With the rapid development of multispectral detection technology, realizing the synergistic camouflage and thermal management of materials in multi-band has become a major challenge. In this paper, a multifunctional radiation-selective hierarchical metamaterial (RSHM) is designed to realize the modulation of optical properties in a wide spectral range through the delicate design of microstructures and nanostructures. In the atmospheric windows of 3–5 μm and 8–14 μm, the emissivity of the material is as low as 0.14 and 0.25, which can effectively suppress the radiation characteristics of the target in the infrared band, thus realizing efficient infrared stealth. Simultaneously, it exhibits high emissivity in the 2.5–3 μm (up to 0.80) and 5–8 μm (up to 0.98) bands, significantly improving thermal radiation efficiency and enabling active thermal management. Notably, RSHM achieves low reflectivity at 1.06 μm (0.13) and 1.55 μm (0.005) laser wavelengths, as well as in the 8–14 μm (0.06) band, substantially improving laser stealth performances. Additionally, it maintains high transmittance in the visible light range, ensuring excellent visual camouflage effects. Furthermore, the RSHM demonstrates exceptional incident angle and polarization stability, maintaining robust performances even under complex detection conditions. This design is easy to expand relative to other frequency bands of the electromagnetic spectrum and holds significant potential for applications in military camouflage, energy-efficient buildings, and optical devices. Full article

With the rise in global temperatures, it is of great significance to achieve rapid and accurate detection of greenhouse gases, such as carbon dioxide and methane. Raman spectroscopy not only overcomes the weakness of absorption spectroscopy in simultaneously measuring homonuclear diatomic molecules but also enables the simultaneous detection of multiple gases using a single-wavelength laser. However, due to the small Raman scattering cross-section and weak intensity of molecules, its application in gas detection is limited. To enhance the intensity of Raman scattering, this paper designs and constructs a multi-pass enhanced Raman spectroscopy setup. This study focuses on the effects of Raman scattering collection geometry, laser multi-pass patterns, and laser polarization relative to the Raman collection direction on signal intensity. Investigations into Raman scattering collection angles of 30°, 60°, and 90° reveal that the Raman scattering signal intensity increases as the collection angle decreases. Different laser multi-pass patterns also impact the signal, with the near-concentric linear multi-pass pattern found to collect more signals. To minimize the influence of excitation light on the signal, a side collection system is employed. Experiments show that the Raman scattering signal is stronger when the laser polarization is perpendicular to the collection direction. This study achieves overall system performance enhancement through coordinated optimization of multiple physical mechanisms, including Raman scattering collection geometry, laser multi-pass patterns, and laser polarization characteristics. The optimized setup was employed to characterize the laser power dependence for nitrogen, oxygen, and carbon dioxide detection. The results showed that the Raman scattering intensity varied linearly with the laser power of the gases, with linear fitting goodness R² values of 0.9902, 0.9848, and 0.9969, respectively. Finally, by configuring different concentrations of carbon dioxide gas using nitrogen, it was found that the Raman scattering intensity varied linearly with the concentration of carbon dioxide, with a linear fitting goodness R² of 0.9812. The system achieves a CO₂ detection limit of 500 ppm at 200 s integration time, meeting the requirements for greenhouse gas emission monitoring applications. Full article

This study presents the performance of a multi-gas sensor for greenhouse detection based on quartz-enhanced photoacoustic spectroscopy (QEPAS). The QEPAS sensor exploits an innovative, compact three-wavelength laser module as excitation source. The module integrates three interband cascade laser chips with a beam combining system, all enclosed in a compact metallic package with sizes of 40 × 52 × 17 mm to generate a single output beam. The multi-gas QEPAS sensor was tested in a laboratory environment for the sequential detection of two greenhouse gases, methane (CH₄) and carbon dioxide (CO₂), and a precursor greenhouse gas, carbon monoxide (CO). At an integration time of 100 ms, minimum detection limits of 21 ppb, 363 ppb, and 156 ppb, were estimated for CH₄, CO_2, and CO detection, respectively, all well below their natural abundance in air. Full article

This article reviews the research progress of all-polarization-maintaining mode-locked fiber lasers. Owing to their excellent resistance to environmental interference and high stability, all-polarization-maintaining mode-locked fiber lasers hold significant application value in various fields, including industrial processing, communications, medical applications, and military applications. This article provides a detailed introduction to the structures, working principles, and performance characteristics of all-polarization-maintaining mode-locked fiber lasers based on different mode-locking mechanisms, such as SESAMs, two-dimensional materials, nonlinear polarization rotation, nonlinear optical loop mirrors, nonlinear amplifying loop mirrors, and figure-9 cavity. Additionally, this article discusses the challenges faced by all-polarization-maintaining mode-locked fiber lasers and their future development directions, including integration, miniaturization, multi-wavelength output, and the potential applications of new materials. Full article

The wavefront aberrations (WAs) of a laser beam produced by an optical parametric oscillator (OPO) have been measured using a Hartmann–Shack sensor. The OPO tuning operation requires changes in the device that might affect the shape of the wavefront beam as the illumination wavelength is being modified. Different output wavelengths in the range 550–850 nm were systematically analyzed in terms of WAs. The WA laser beam was fairly stable with time (changes of about 1%), independently of the wavelength. Moreover, WAs were non-negligible and nearly constant between 600 and 800 nm, but they noticeably increased for 550 (~90%) and 850 nm (~50%), mainly due to a higher astigmatism influence. The contributions of other higher-order terms such as coma and spherical aberration also present particular spectral dependences. To our knowledge, this is the first report of a spectral OPO laser beam characterization in terms of optical aberrations. It addresses a gap in OPO laser characterization of WAs and offers actionable insights for multi-wavelength applications. These results might be useful in applications ranging from micromachining procedures to biomedical imaging, where an optimized focal spot is required to increase the efficiency of certain physical phenomena or to enhance the quality of the acquired images. Full article

Although lasers are widely used in various industries, including aviation, healthcare, and communication engineering, there has been little research concentrated on the field of horticulture. In this paper, five semiconductor pumped fiber-coupled lasers emitting laser pulses of different wavelengths (450 nm, 532 nm, 808 nm, 915 nm, and 1064 nm) were used in the experimental drilling and cutting of hedge branches. A drilling effect on the hedge branches as a function of the laser power density, incident angle, and defocus condition was demonstrated, and it was found that a laser with a central wavelength of 450 nm had the lowest drilling power density and the shortest drilling-through time. It also enables the maximum tolerance of changes to the incident angle. The reason is closely related to the different absorption coefficients of lasers of various wavelengths on the hedge branches. In the cutting experiment, a laser at a wavelength of 450 nm was used, and the scanning speed of the laser was optimized. Good cutting effects were found at laser scanning speeds ranging from 18 mm/s to 23 mm/s. The layer of carbide formed by cutting the hedge branches can effectively block the invasion of bacteria, which is the advantage of using laser cutting in the field of horticulture. Full article

Nanosecond laser ablation effectively modifies Cu-ETP copper surfaces by controlling wettability and microstructure. This study examines the effects of nanosecond fiber laser processing and subsequent oxidation on surface evolution. The analyzed parameters include fluence (25.46–1018.59 J/cm²), wavelength (1064 nm), repetition rate (25–1000 kHz), and pulse duration (2–500 ns). To investigate high energy densities, fluence values were set above typical ablation thresholds, inducing hierarchical surface structures affecting wettability. Post-ablation oxidation was examined under two conditions: natural oxidation in ambient air and accelerated oxidation via low-temperature annealing (200 °C) in air. Contact angle measurements revealed that over time, the initially hydrophilic (θ < 90°) laser-textured surfaces exhibited a transition toward hydrophobicity (θ > 90°), which can be attributed to the adsorption of airborne organic compounds rather than oxidation alone. In contrast, annealing significantly accelerated hydrophobicity, attributed to controlled copper oxide growth. SEM and EDS analyses confirmed that higher fluences enhanced roughness and oxidation, forming multi-scale textures and oxide layers, which influenced water repellency. These findings demonstrate that high-fluence laser ablation, combined with controlled oxidation, enables precise wettability engineering. This method provides an efficient strategy for tuning surface properties, offering potential applications in anti-corrosion coatings, self-cleaning surfaces, and heat exchangers, where hydrophobicity and durability are essential. Full article

The use of bound states in the continuum (BICs) has emerged as an effective tool to trap light at the nanoscale and has many potential applications in photonics. Breaking the structural symmetry is regarded as an effective way to excite quasi-BICs (QBICs) and generate high-Q resonances. However, this approach may impact the resonance polarization sensitivity, consequently limiting its practicality in multi-wavelength polarization-dependent applications. Furthermore, the introduction of different types of structural perturbations into the design to form BICs has yet to be explored in depth. In this study, we present an optical sensor consisting of an L-shaped metasurface that supports three quasi-BIC modes in the terahertz band, where specific displacements, collective perturbations, or both occur. Furthermore, we analyze the field distributions in detail and combine them with multipolar decomposition to reveal the underlying mechanisms of the different resonant modes. Multiple asymmetric perturbations are found to affect the sensitivity of the metasurface in refractive index sensing, thus allowing for a comparison of different resonant modes. The quasi-BIC mode can attain a Q-factor of 1067.6, a sensitivity (S) of 300 GHz/RIU, and a figure of merit (FOM) of 5367.8 RIU⁻¹ for vertical light incidence. These three quasi-BIC modes are polarization-independent, and their properties are maintained even for circularly polarized light. The results reveal a novel design strategy for metasurface-based sensors with promising application potential in biosensing, filtering, and lasers. Full article

A short-circuited coupling structure (SCCS) is proposed to obtain a gain-filtering response for dual-polarized antennas. A conventional dipole is designed with two intrinsic radiation nulls. By introducing an SCCS, an additional radiation null is obtained, and the impedance bandwidth of an antenna can be further improved. Based on this design principle, two dual-polarized filtering antennas are designed for 4G and 5G wireless communication devices. The impedance bandwidth of the proposed 4G filtering antenna is 1.63–2.97 GHz (|S11| < −15 dB), with four radiation nulls at 1.1 GHz, 3.25 GHz, 3.5 GHz, and 4.0 GHz. The impedance bandwidth of the proposed 5G filtering antenna is 3.23–4.21 GHz (|S33| < −15 dB), with four radiation nulls at 1.7 GHz, 2.5 GHz, 3 GHz, and 4.6 GHz. Further, the decoupling function of the SCCS on 4G/5G MIMO antenna designs is also discussed. When introducing an SCCS, the port isolation levels of two elements between the 4G and 5G antennas, as well as the adjacent 5G antennas, can be improved by 14 dB and 6 dB, respectively. The port isolation levels of five elements between the 4G and 5G antennas, as well as the adjacent 5G antennas, can be improved by 15.2 dB and 9.5 dB, respectively. This technique could also be a potential candidate for optical antenna designs in optical front-ends and other multi-wavelength fiber lasers with microstructures. Full article

A wideband dual-polarized dielectric resonator antenna (DRA) with gain-filtering response was proposed in this paper. First, a differentially fed, low-profile crossed-DRA was used to obtain orthogonal polarizations with two resonant modes. A radiation null at upper band edge was also generalized. Second, with the introduction of four parasitic patches at the top of the crossed DRA, another resonant mode at lower band was excited, and the bandwidth was greatly expanded. Moreover, the introduction of parasitic patches could also help improve the selectivity of realized gain with another radiation null at the upper band edge. Furthermore, four sequentially rotated shorting coupling structures (SRSCSs) were proposed for the first time to generalize two additional radiation nulls. Finally, a wideband bandpass filtering response of the realized gain with four radiation nulls was obtained. Prototypes of the proposed antennas were fabricated, and the testing results showed that the antenna had a wide operation band of 57.1% from 2.75 GHz to 4.95 GHz with sharp roll-off at the band edge. This technique could also be used in wireless communication devices at millimeter/optical front ends and other multi-wavelength fiber lasers with micro structures. Full article

Hyperspectral imaging and laser technology both rely on different wavelengths of light to analyze the characteristics of materials, revealing their composition, state, or structure through precise spectral data. In hyperspectral image (HSI) classification tasks, the limited number of labeled samples and the lack of feature extraction diversity often lead to suboptimal classification performance. Furthermore, traditional convolutional neural networks (CNNs) primarily focus on local features in hyperspectral data, neglecting long-range dependencies and global context. To address these challenges, this paper proposes a novel model that combines CNNs with an average pooling Vision Transformer (ViT) for hyperspectral image classification. The model utilizes three-dimensional dilated convolution and two-dimensional convolution to extract multi-scale spatial–spectral features, while ViT was employed to capture global features and long-range dependencies in the hyperspectral data. Unlike the traditional ViT encoder, which uses linear projection, our model replaces it with average pooling projection. This change enhances the extraction of local features and compensates for the ViT encoder’s limitations in local feature extraction. This hybrid approach effectively combines the local feature extraction strengths of CNNs with the long-range dependency handling capabilities of Transformers, significantly improving overall performance in hyperspectral image classification tasks. Additionally, the proposed method holds promise for the classification of fiber laser spectra, where high precision and spectral analysis are crucial for distinguishing between different fiber laser characteristics. Experimental results demonstrate that the CNN-Transformer model substantially improves classification accuracy on three benchmark hyperspectral datasets. The overall accuracies achieved on the three public datasets—IP, PU, and SV—were 99.35%, 99.31%, and 99.66%, respectively. These advancements offer potential benefits for a wide range of applications, including high-performance optical fiber sensing, laser medicine, and environmental monitoring, where accurate spectral classification is essential for the development of advanced systems in fields such as laser medicine and optical fiber technology. Full article