Search Results (96)

The archaeological terraces of Petra (southern Jordan) have long been recognized for their role in agriculture and flood mitigation. Despite the dominance of fine-grained sediments behind many terrace walls, these systems exhibit high infiltration capacity and remarkable resistance to erosion. This study investigates the hydrological behavior of terrace-trapped sediments through detailed soil texture, aggregate stability, salinity, and chemical analyses across eight representative sites in and around Petra. Grain-size distributions derived from dry and wet sieving, supplemented by laser diffraction, reveal that dry sieving substantially overestimates sand content due to aggregation of fine particles into unstable peds. Wet analyses demonstrate that many terrace soils are clay- or sandy-clay-dominated yet remain highly permeable. Chemical indicators (nitrate, phosphate, potassium, pH, and salinity) further suggest that terracing enhances downward water movement and salt leaching irrespective of clay content. The nature of the terrace settings and their sediment structure (especially the coarse-grained framework) exerts a stronger control on hydrological functioning than texture alone. The results have direct implications for understanding ancient land management in Petra and for informing sustainable terracing practices in modern arid and semi-arid landscapes, as they are effective both in harvesting water and reducing sediment mobilization. Full article

Under the dual pressures of global climate change and accelerating urbanization, landscape design has been tasked with the critical mission of enhancing urban environmental resilience and ecological livability. However, conventional design practices often struggle to efficiently integrate complex sustainability norms with aesthetic creativity, leading to a disconnect between form and function. To address this issue, this study proposes and validates an AI-enabled sustainability decision-support framework. The framework is based on a “Generative-Critical” multi-agent workflow that enables “Self-Correcting” iterative optimization of design schemes through a built-in expert knowledge base and a quantitative scorecard. The framework’s effectiveness was validated through a cultural park case study and a blind evaluation by 10 experts. It guided a design from an initial concept with only aesthetic forms and lacking effective stormwater management, to an ecologically integrated scheme that strategically incorporated bioretention ponds at key nodes and converted hard plazas into permeable pavements. This transformation significantly elevated the scheme’s sustainability score from 59.3 to 88.0 (p < 0.001), while the framework itself achieved a high system usability scale (SUS) score of 85.5. These results confirm that the proposed “Generative-Critical” mechanism can effectively guide AIGC to adhere to ecological-technical norms and constraints while pursuing aesthetic innovation, thereby achieving a scientific integration of aesthetic form and ecological function at the early conceptual design stage. This study offers a scalable methodology for AI-assisted sustainable design and provides a novel intelligent tool for creating resilient urban landscapes that possess both environmental performance and aesthetic value. Full article

Inorganic polyphosphate is highly conserved, critical, yet poorly understood polymer that regulates diverse cellular functions in mammals. Its importance is well established in coagulation, inflammation, mitochondrial function, and stress responses, though the molecular mechanisms for these effects remain only partly understood. Fundamental questions also persist regarding its physiological concentration, chain-length distributions, and the mechanisms that regulate its behavior in specific cellular compartments. Progress is limited by the absence of a known mammalian polyphosphate-synthesizing enzyme. Despite this, recent studies have broadened the scope of polyphosphate biology, suggesting roles in protein phase separation, ATP-independent chaperone activity, metabolic regulation, and intracellular signaling. Polyphosphate modulates the mitochondrial permeability transition pore through calcium-dependent regulation and activates factor XII in coagulation. Findings have also introduced potential connections between polyphosphate and processes such as neurodegeneration, cancer, and tissue regeneration. Despite this expanding landscape, many biological effects remain difficult to interpret due to incomplete mapping of protein targets and longstanding technical limitations in detecting and quantifying polyP. This review integrates molecular protein-interaction mechanisms with compartment-specific functions and disease physiology, providing a clearer mechanistic framework while identifying key conceptual and methodological gaps and outlining priorities for advancing polyphosphate research in mammalian systems. Full article

Urban green spaces are pivotal to enhancing carbon sinks and advancing carbon neutrality goals, yet the structural complexity of green space units often leads to scale mismatches and weak spatial responsiveness in current assessments. This study develops an integrated evaluation framework that combines landscape spatial unit typologies with life-cycle-based carbon flux modeling. We defined 22 landscape spatial unit types based on two-dimensional surface cover and three-dimensional vegetation structure, including waterbodies and vertical greening. A life-cycle carbon model was developed with indicators covering unit carbon sink, unit carbon emission, unit net carbon sink efficiency, and time to carbon balance. Taking Luhe Park in Nanjing as a case study, the carbon sink efficiency indicators were quantified for 108 units over a 50-year cycle. Results indicate that multilayer vegetation structures, high green coverage, and moderate-to-high planting density markedly enhance carbon sink efficiency, whereas extensive built surfaces and high impervious ratios suppress it. K-means clustering classified the spatial units into four types with emphasis on efficiency-driven, structural optimization, functional compatibility, and imbalance compensation, respectively, revealing a clear gradient tied to spatial configuration. To translate diagnosis into design, we report 95% confidence intervals of key structural factors as actionable thresholds. These ranges inform targeted interventions such as maintaining continuity and multilayer structure in high-efficiency areas, modest structural upgrades with native drought-tolerant plants, edge greening with permeable pavements in open spaces, and streamlined vertical systems linked to adjacent high-sink ground units. The framework delivers spatially explicit, life-cycle-aware evidence to support low-carbon planning and design of urban green spaces. Full article

In the São Brás de Alportel municipality, water scarcity poses a significant constraint on agricultural activities. This study utilises Remote Sensing (RS) and Geographical Information Systems (GISs) to identify existing irrigated areas, delineate catchment basins, and select the most suitable sites for the installation of new surface water reservoirs. First, the principal territorial components were characterised, including physical elements (climate, geology, soils, and hydrography) and anthropogenic infrastructure (road network and high-voltage power lines). Summer Sentinel-2 satellite imagery was then analysed to calculate the Normalised Difference Vegetation Index (NDVI), enabling the identification and classification of irrigated agricultural parcels. Flow directions and accumulations derived from Digital Elevation Models (DEMs) facilitated the characterisation of 38 micro-catchments and the extraction of 758 km of the drainage network. The siting criteria required a minimum setback of 100 m from roads and high-voltage lines, excluded farmland currently in use, and favoured mountainous areas with low permeability. Only 18.65% (2854 ha) of the municipality is agricultural land, of which just 4% (112 ha) currently benefits from irrigation. The NDVI-based classification achieved a Kappa coefficient of 0.88, indicating high reliability. Three sites demonstrated adequate storage capacity, with embankments measuring 8 m, 10 m, and 12 m in height. At one of these sites, two reservoirs arranged in a cascade were selected as an alternative to a single structure exceeding 12 m in height, thereby reducing environmental and landscape impact. The reservoirs fill between October and November in an average rainfall year and between October and January in a dry year, maintaining a positive annual water balance and allowing downstream plots to be irrigated by gravity. The methodology proved to be objective, replicable, and essential for the sustainable expansion of irrigation within the municipality. Full article

To mitigate the impacts of urbanisation and the attendant surface sealing, appropriate measures are required when adapting urban spaces and drainage infrastructure. In this context, the deployment of Sustainable Drainage Systems (SuDSs) has emerged as a viable alternative, delivering highly positive outcomes by enhancing hydrological, hydraulic and landscape performance while restoring ecosystem services to the community. This study evaluates the relative performance of five SuDS typologies, green roofs, bioretention cells, infiltration trenches, permeable pavements, and rain barrels, implemented in a 64 ha subbasin of the metropolitan area of Barcelona, Spain. Using Giswater integrated with the SWMM, the stormwater drainage network was modelled under multiple rainfall scenarios. Performance was assessed using two qualitative indicators, the junction index (I_j) and the conduit index (I_c), which measure surcharge levels in manholes and pipes, respectively. The results show that SuDS implementation affecting 42.8% of the drained area can enhance network performance by 35.6% and reduce flooded junctions by 67%. Among the typologies, rain barrels and bioretention cells were the most effective. The study concludes that SuDS construction, supported by open-source tools and performance-based indicators, constitutes a replicable and technically robust strategy for mitigating the effects of surface sealing and increasing urban resilience. Full article

By combining social, ecological, and communal elements, urban parks significantly improve the quality of urban life. This paper explores the revitalization proposal for Areos Park in Tripoli, Greece, viewing it as an urban palimpsest reflecting layers of history, culture, and nature. While historically evolving from exclusive enclaves to vital public spaces fostering social equity and well-being, many urban parks, including those in Greece, suffer from neglect and underfunding, diminishing their landscape value and necessitating revitalization. Areos Park exemplifies these challenges, making it an ideal case study for exploring effective urban park revitalization strategies and demonstrating how urban areas can host critical landscape functions. Utilizing a design-based research (DBR) methodology, a design plan is proposed. The architectural concept focuses on revamping key areas, restoring historical features, adding small constructions, and repurposing existing buildings for community and educational uses. Concurrently, the landscape concept emphasizes biodiversity enrichment and ecological restoration through permeable surfaces and native Mediterranean vegetation, contributing to urban resilience to climate change. The overall design prioritizes accessibility and spatial connectedness to create an inclusive, resilient, and adaptable urban park addressing contemporary sustainability challenges and biodiversity loss. The project aims to establish Areos Park as a model for sustainable urban park regeneration in small cities, blending ecological enhancement with historical preservation. Full article

The traditional Arab-Islamic urban fabric of Riyadh, with its emphasis on privacy, social cohesion, and environmental adaptation, was radically disrupted when the 1970s Doxiadis master plan was implemented, transforming the city into a car-dependent gridiron design. The shift led to ever-spreading sprawl, reduced pedestrian-friendliness, and eroded local identity. Using Hegelian dialectics methodology, this paper proposes integration of fused grid theory and urban Islamic fractals geometry in the urban fabric of the city. Specifically for Riyadh, the proposed changes encourage urban quadrant nesting, change of block scale and layout, fractal landscape integration, and multi-modal permeability. These adaptations are intended to increase connectivity, reduce crash rates, minimize impacts on the environment, enhance walkability, and elevate overall quality of life. Full article

Celiac disease (CeD) is a chronic autoimmune enteropathy triggered by dietary gluten in genetically predisposed individuals. Along with other disorders such as non-celiac gluten/wheat sensitivity and gluten allergy, adherence to a strict gluten-free diet (GFD) is required as the only effective treatment for CeD. To this end, and partially due to the burdensome nature and limited efficacy in some patients of a GFD, significant research into alternative therapies has been catalyzed. This review gives a perspective on current and emerging treatment strategies targeting different aspects of CeD pathogenesis. These include gluten-degrading enzymes (e.g., AN-PEP, Latiglutenase, Zamaglutenase), gluten-sequestering agents (e.g., AGY-010, BL-7010), modulators of intestinal permeability (e.g., Larazotide acetate, IMU-856), immune-modulating agents (e.g., ZED1227, AMG 714, EQ102), and strategies for immune tolerization (e.g., TAK-101, KAN-101, Nexvax2). Newer approaches are also targeting probiotics to modulate the gut microbiota (e.g., VSL#3, Lactobacillus plantarum HEAL9), nutraceuticals (e.g., polyphenols, vitamins), or food modifications to remove the gluten from naturally gluten-containing foodstuffs (e.g., gluten transamidation, Gluten Friendly™ technology). Despite encouraging results in preclinical and clinical trials, no treatment has yet been conclusively proven to serve as an effective alternative to the GFD. Continued research is essential to validate efficacy, optimize dosing, and ensure safety in broader patient populations. Here, we provide a comprehensive overview of the therapeutic landscape for CeD, analyze the main strengths and limitations of each treatment and highlight promising directions for future management of CeD, altogether evidencing the urgent need to develop effective alternatives for these patients. Full article

The objective of this article is to propose a novel model for evaluating retention solutions in urban areas. This model is designed to serve as a tool to support integrated urban planning in the context of reurbanization and climate change adaptation processes. The model is both diagnostic and decision-support in nature, integrating spatial, environmental, and functional data. It analyzes these data based on a spatial dependency matrix. A comprehensive consideration of both physiographic factors (e.g., geomorphological typology and land ownership) and social and institutional factors (e.g., institutional readiness and stakeholder engagement) was undertaken. The modelling employs methodologies that are characteristic of urban and landscape design, including multi-criteria analysis, case studies, expert assessment, and Geographic Information System (GIS) tools. The assessment of the retention potential was conducted with consideration for the typology of buildings, infiltration capacity, soil permeability, and existing infrastructure. The findings of the present study demonstrate that local spatial and social conditions exert a substantial influence on the efficacy of retention implementation. The model enables the prioritization of actions and the selection of suitable solutions (context-sensitive retention strategies), thus making it a valuable instrument for designers, urban planners, and decision-makers. The proposed approach can be used in urban planning as a practical tool to support decisions on resilient city development and urban water management. Full article

Historic districts are key urban spaces that convey cultural heritage and support tourism and social interaction. As the spatial interface shapes form and perception, this study explores youth-oriented visual behaviour and cognitive preferences regarding historic street interfaces. Using Kuan-Narrow Alley in Chengdu as a case study, we analysed eye-tracking data to assess visual engagement with interface elements. Architectural components received the highest attention for Total Fixation Duration, Fixation Count, and Visit Count, while commercial elements yielded a longer Average Fixation Duration. A multiple linear regression model identified Historical Linguistic Landscape (β = 1.088), Street Permeability (β = 0.401), and Street Width-to-Height Ratio (β = 0.178) as significant predictors of perceived usability, with Historical Linguistic Landscape proving most influential. These findings underscore the value of preserving cultural significance in streetscape morphology and provide theoretical and practical insights from a youth-centric perspective. By integrating eye-tracking with morphological analysis, the study offers a novel approach to understanding visual perceptions in historic districts. Despite limitations in sample size and scope, the study provides solid insights, with future research needed to broaden contexts for greater generalisability. Full article

Amphibians are particularly vulnerable to hydric stress due to their permeable skin, biphasic life cycle, and strong dependence on aquatic and moist terrestrial environments. In the Northwestern Mediterranean Basin—one of Europe’s most climate-sensitive regions—the intensification of droughts associated with climate change poses a critical threat to amphibian populations. Increased aridification, either due to higher temperatures or to more frequent, prolonged, and severe drought episodes, can affect both aquatic and terrestrial life stages, directly altering breeding opportunities, larval development, post-metamorphic survival, and dispersal capacity. This review aims to gather and synthesize current knowledge on the ecological, physiological, and demographic impacts of drought on amphibians of the Northwestern Mediterranean across habitat types, including ephemeral ponds, permanent water bodies, lotic systems, and terrestrial landscapes, including a final section on possible mitigation actions. Drought-induced shifts in hydroperiod can drastically reduce reproductive success and accelerate larval development with fitness consequences while, on land, desiccation risk and habitat degradation could limit access to refugia and fragment populations by reducing structural connectivity. These environmental constraints are compounded by the interactions between drought and emerging infectious diseases. We discuss the current knowledge on how chytrid fungi (Batrachochytrium dendrobatidis and B. salamandrivorans) and ranaviruses may respond to temperature and moisture regimes, and how drought may affect their transmission dynamics, host susceptibility, and pathogen persistence. In these cases, microbiome disruption, pollutant concentration, and increased contact rates between species may amplify disease outbreaks under dry conditions, but a better understanding of the multifactorial effects of drought on amphibian biology and disease ecology is needed for predicting species vulnerability, identifying high-risk populations, and guiding future conservation and management strategies in Mediterranean environments. Full article

In the context of the evolving global energy landscape, tight gas fields have gained in-creasing significance due to their low-porosity and low-permeability reservoirs, where natural fractures play a critical role in improving permeability and enhancing storage capacity. Foreland basins, such as the Dibei area in the northern Kuqa Depression of the Tarim Basin, are typical hosts for tight gas reservoirs, but the complex fracture development induced by multiple tectonic movements restricts natural gas exploration. This study employs core observation, imaging logging analysis, and thin-section microscopy to characterize the genetic types and development features of natural fractures in the Ahe Formation. Results show that 54% of natural fractures in the Dibei area are structurally originated, predominantly high-angle and open. The highest fracture density (0.351 fractures/m), six times that of other regions, occurs in the upper horst zones. Three fracture patterns are identified, namely fault–fold, fault-related, and monocline types. Fault–fold fractures are most developed due to folding and thrusting, while monocline zones are poorly fractured. Structural fractures are best developed in horst crests with fault–fold patterns. Fracture development is jointly controlled by folds, faults, stress, and lithology, with distinct characteristics across different structural positions and lithological combinations. Clarifying the development characteristics and distribution patterns of natural fractures in the Ahe Formation of the Dibei area facilitates accurate evaluation of high-quality reservoirs, providing crucial geological basis for optimizing hydrocarbon sweet spots and refining accumulation models in the region. Full article

Global warming has resulted in an increase in the frequency of extreme high-temperature events. High temperatures can increase cell membrane permeability, elevate levels of osmotic adjustment substances, reduce photosynthetic capacity, impair plant growth and development, and even result in plant death. Under high-temperature stress, plants mitigate damage through physiological and biochemical adjustments, heat signal transduction, the regulation of transcription factors, and the synthesis of heat shock proteins. However, different plants exhibit varying regulatory abilities and temperature tolerances. Investigating the heat-resistance and regulatory mechanisms of plants can facilitate the development of heat-resistant varieties for plant genetic breeding and landscaping applications. This paper presents a systematic review of plant physiological and biochemical responses, regulatory substances, signal transduction pathways, molecular mechanisms—including the regulation of heat shock transcription factors and heat shock proteins—and the role of plant hormones under high-temperature stress. The study constructed a molecular regulatory network encompassing Ca²⁺ signaling, plant hormone pathways, and heat shock transcription factors, and it systematically elucidated the mechanisms underlying the enhancement of plant thermotolerance, thereby providing a scientific foundation for the development of heat-resistant plant varieties. Full article

The dramatic increase in urban construction waste poses severe environmental challenges. Utilizing waste concrete to produce recycled aggregates (RA) for manufacturing recycled concrete (RC) represents an effective strategy for resource utilization. However, inherent defects in RA, such as high porosity, microcracks, and adherent old mortar layers, lead to significant performance degradation of the resulting RC, limiting its widespread application. Traditional methods for enhancing RA often suffer from limitations, including high energy consumption, increased costs, or the introduction of new pollutants. MICP offers an innovative approach for enhancing RC performance. This technique employs the metabolic activity of specific microorganisms to induce the formation of a three-dimensionally interwoven calcium carbonate gel network within the pores and on the surface of RA. This gel network can improve the inherent defects of RA, thereby enhancing the performance of RC. Compared to conventional techniques, this approach demonstrates significant environmental benefits and enhances concrete compressive strength by 5–30%. Furthermore, embedding mineralizing microbial spores within the pores of RA enables the production of self-healing RC. This review systematically explores recent research advances in microbial mineral gel network for improving RC performance. It begins by delineating the fundamental mechanisms underlying microbial mineralization, detailing the key biochemical reactions driving the formation of calcium carbonate (CaCO₃) gel, and introducing the common types of microorganisms involved. Subsequently, it critically discusses the key environmental factors influencing the effectiveness of MICP treatment on RA and strategies for their optimization. The analysis focuses on the enhancement of critical mechanical properties of RC achieved through MICP treatment, elucidating the underlying strengthening mechanisms at the microscale. Furthermore, the review synthesizes findings on the self-healing efficiency of MICP-based RC, including such metrics as crack width healing ratio, permeability recovery, and restoration of mechanical properties. Key factors influencing self-healing effectiveness are also discussed. Finally, building upon the current research landscape, the review provides perspectives on future research directions for advancing microbial mineralization gel techniques to enhance RC performance, offering a theoretical reference for translating this technology into practical engineering applications. Full article