Search Results (70)

As a key branch of online-to-offline (O2O) retail, the online-to-home (O2H) model enables goods acquisition through instant delivery, fundamentally reorienting urban retail spatial configuration from “accessibility” to “efficiency”. Using Jincheng, the main urban area of Tianjin as a case study, this research formulated a Goods Acquisition Efficiency (GAE) index to quantify the time-based efficiency gain of O2H over the conventional OIS (offline in-store) mode. An integrated XGBoost-SHAP approach was utilized to examine the spatial variations in efficiency gains and their associated factors. The results reveal that: (1) Efficiency gains follow a concentric pattern, increasing from the core to the periphery (Inner: 0.18; Middle: 0.20; Outer: 0.26), suggesting that O2H provides more pronounced benefits in peripheral areas where retail provision remains limited; (2) The dominant factors vary across zones: environmental attributes in the Inner Urban Zone, transportation and economic factors in the Outer Urban Zone; (3) O2H and OIS exhibit a complementary rather than substitutive relationship—physical stores in inner-city areas can maintain their current configuration, while peripheral zones may benefit from enhanced O2H fulfillment or conversion to micro-fulfillment centers. The GAE index and zonal comparison framework offer methodological references for differentiated optimization of urban retail networks. Full article

In the rapidly urbanizing Global South, megacities face a perplexing “paradox of idleness”: acute land scarcity in the urban core coexisting with inefficient rural homesteads in the hinterland. Using Shanghai as a representative case, this study integrates spatial autocorrelation analysis with Geographical Detector modeling to quantify the spatial differentiation patterns and driving mechanisms of this phenomenon. The results reveal a distinct core-periphery gradient, with vacancy density increasing from the inner suburbs to the remote hinterland. Four regional typologies were identified: dispersed-inefficient, high-density accumulation, sparse-stable, and intensive-efficient. Quantitative analysis identifies demographic aging and low agricultural efficiency as dominant drivers. Counter-intuitively, the study finds that top-down institutional pilots alone exert a negligible direct impact. Instead, interaction analysis confirms a significant policy-bundling effect, in which institutional tools promote revitalization only when coupled with economic and locational incentives. These findings expose a mechanism of “involuntary vacancy” trapped by institutional rigidity, distinct from the market-driven abandonment seen in shrinking or remote Western contexts. Consequently, a gradient-based governance framework is proposed to transition from “one-size-fits-all” regulation to targeted spatial restructuring pathways. Full article

Research on culture-led urban change in China has shifted from inner-city clusters to peripheral zones where formal planning meets managed informality, yet two gaps remain. First, artistic production continues to be interpreted through a leasing lens that positions artists as temporary occupiers. Second, land is analysed largely at the macro scale of municipal supply and branding, while internal property rules and meso-level governance are overlooked. This paper mobilises the concept of assetisation to show how precarious cultural spaces become rule-bound assets through property-rights design. Fieldwork in Chengdu’s Blue Roof Art District draws on qualitative methods, including semi-structured interviews, policy and registration documents, and on-site observation. We examine which resources are assetised, how this occurs, and with what effects on publicness and spatial form. Our findings show that planning endorsement, the transfer of collective construction land for cultural use, and title registration with mortgageability codify eligibility, use and transfer. Studios are converted into owner-occupied assets tied to land value. Governance shifts from direct administrative control to asset management by owners and the site operator. While production stabilises and overt conflict declines, public interfaces narrow and enclave risks intensify when city priorities change. Empirically, the paper demonstrates how property-rights design operates as a meso-level governance tool that sets explicit trade-offs between stability and openness. Theoretically, it links producers to land value, bridging macro land regimes with micro political practice in urban peripheries and informing urban policy-making that prioritises sustainability. Full article

Image convolution is a commonly required task in machine vision and Convolution Neural Networks (CNNs). Due to the large data movement required, image convolution can benefit greatly from in-memory computing. However, image convolution is very computationally intensive, requiring ${(n-(k-1))}^2$ Inner Product (IP) computations for convolution of a $n\times n$ image with a $k\times k$ kernel. For example, for a convolution of a 224 × 224 image with a 3 × 3 kernel, 49,284 IPs need to be computed, where each IP requires nine multiplications and eight additions. This is a major hurdle for in-memory implementation because in-memory adders and multipliers are extremely slow compared to CMOS multipliers. In this work, we revive an old technique called ‘Distributed Arithmetic’ and judiciously apply it to perform image convolution in memory without area-intensive hard-wired multipliers. Distributed arithmetic performs multiplication using shift-and-add operations, and they are implemented using CMOS circuits in the periphery of ReRAM memory. Compared to Google’s TPU, our in-memory architecture requires 56× less energy while incurring 24× more latency for convolution of a 224 × 224 image with a 3 × 3 filter. Full article

Urban green spaces (UGSs) are critical to ecological sustainability and human well-being, but equitable access remains a key challenge, particularly in high-density cities. While existing studies have predominantly focused on parks, the role of non-park green spaces (NPGSs) has received limited attention. This study examines the spatial equity of NPGSs—an overlooked but essential component of urban green infrastructure in Inner London—using a typological classification informed by previous research, along with multi-threshold accessibility assessment and spatial justice evaluation. We apply GIS-based buffer analysis, decomposed Gini coefficients, and Moran’s I clustering to quantify distributional disparities. The main findings are as follows: (1) five NPGS types are defined and mapped in Inner London: Natural and Protected, Community and Household, Purpose-Specific, Linear, and Underutilized; (2) significant accessibility inequities exist among NPGS types, with Community and Household demonstrating high equity (Gini coefficient < 0.25), while Underutilized exhibit severe deprivation (Gini coefficient > 0.74); (3) spatial clustering analysis reveals a core–periphery differentiation, characterized by persistent low–low clusters in central boroughs and emerging high–high hot spots in southeastern/northwestern boroughs. This study underscores the critical role of NPGS in complementing park-based greening strategies and provides a transferable framework to assess green equity, thereby contributing to the achievement of the United Nations Sustainable Development Goals (SDGs). Full article

Against a global backdrop of industrialization and urbanization, precise measurement of multifactor flows and systematic identification of barriers and drivers are critical for optimizing resource allocation in smart regional development. This study develops an integrated geospatial analytic framework that incorporates mobile signaling data and POI data to quantify the intensity, barriers, and driving mechanisms of urban–rural factor flows in Huzhou City at the township scale. Key findings reveal the following. (1) Urban–rural factor flows exhibit significant spatial polarization, with less than 20% of connections accounting for the majority of flow intensity. The structure shows clear core–periphery differentiation, further shaped by inner heterogeneity and metropolitan spillovers. (2) Barriers demonstrate complex and uneven spatial distributions, with 45.37% of the integrated flow intervals experiencing impediments. Critically, some nodes act as both facilitators and obstacles, depending on the flow type and direction, revealing a metamodern tension between promotion and impairment. (3) Economic vitality plays a crucial role in driving urban–rural factor flow, with different factors having complex, often synergistic or nonlinear effects on both single and integrated flows. The study advances the theoretical understanding of heterogeneous spatial structures in urban–rural systems and provides a replicable analytical framework for diagnosing factor flows in small and medium-sized cities. These insights form a critical basis for designing targeted and adaptive regional governance strategies. Full article

Numerous thermal practical applications utilize shell and tube heat exchanger appliances to transfer heat energy between hot and cold working fluids. Incorporating metal foam to the outer periphery of inner tube improves the heat transfer process from hot water in the tube side to cold water in the shell side and consequently improves heat exchanger performance. In this study, the integration of use of a porous material together with designing a robust adaptive controller could efficiently regulate the outlet cold water temperature to the desired value. This is achieved with respect to the time required for cold water to reach the desired temperature (settling time) and the amount of hot water volume flow during a certain time span. A barrier function-based adaptive sliding mode controller (BF-based adaptive SMC) is proposed, which requires only the information of temperature measurement of cold water. The stability of BF-based adaptive SMC is proved utilizing Lyapunov function analysis. The effectiveness of proposed controller is verified via numerical results, which showed that the proposed controller could achieve considerable accuracy of cold water temperature using suitable design parameters. In addition, the robustness of controller against variation in inlet temperature is also verified. Another improvement to performance of heat exchanger system is achieved by adding the metal foam of aluminum material on inner pipe perimeter with wide range of metal foam to outer inner pipe diameters ratio ($1\le s\le 1.8$). The results showed that the settling time is significantly reduced which enables outlet cold water to reach the required temperature faster. With respect of the case of non-adding metal foam on inner pipe outer circumference, when $s=1.2$, the settling time and hot water temperature are reduced by $1/2$ and $17.3\%$, respectively, while for $s=1.8$, they are decreased by $\le 1/20$ and $35.3\%$ correspondingly. Accordingly, the required volume flow for hot water is reduced considerably. Full article

Soil carbon constitutes the largest terrestrial carbon reservoir, with inorganic forms (SIC) contributing an estimated 20–40% of the global total. Despite its relevance to arid-region carbon cycling and stabilization, SIC remains less studied than soil organic carbon (SOC). This study quantified surface SIC content (0–20 cm) and its environmental drivers across the Weibei Loess region using 3261 soil samples collected between 2008 and 2010. A combination of Random Forest (RF) modeling and optimal parameter geodetector (OPGD) analysis was employed to assess spatial heterogeneity and identify key environmental controls. SIC content ranged from 0.10 to 3.56 g kg⁻¹ (mean = 1.23 ± 0.41 g kg⁻¹), generally lower than reported values in the Tibetan Plateau and Inner Mongolia. Higher concentrations were observed in central areas, with lower values toward the periphery. While mean annual temperature (MAT) and precipitation (MAP) remained key climatic correlates, shortwave radiation (srad) emerged as the strongest control on SIC across the region, exhibiting a significant positive association with its accumulation. Notably, its interaction with wind speed (vs) further amplified this effect, highlighting the synergistic role of radiation and near-surface turbulence in regulating inorganic carbon retention in surface soils. Collectively, these variables explained ~56% of SIC spatial variation. Favorable conditions for SIC accumulation were identified within specific environmental thresholds: srad (171–172 W/m²), MAP (546–587 mm), MAT (10.2–11.5 °C), and vs (1.90–1.96 m/s). These findings offer a quantitative basis for understanding SIC patterns in loess-derived soils and support the development of region-specific strategies for carbon regulation under changing climatic conditions. Full article

Background: Inner hair cell (IHC) ribbon synapses are the initial synapses in the auditory pathway, comprising presynaptic ribbons and postsynaptic glutamate receptors on the peripheral afferent fibers. The excitatory neurotransmitter glutamate primarily signals through AMPA-type heterotetrameric receptors (AMPARs), composed of GluR1, GluR2, GluR3, and GluR4 subunits. Research shows that corticosterone affects AMPA receptor subunits in the central nervous system. The present study investigates the effects of corticosterone on AMPA receptor subunits in the murine cochlea. Methods: Cochlear explants were isolated from male and female C57BL/6 pups (postnatal days 4–5), treated for 20 min with 100 nM corticosterone, and cultured for an additional 24 h. The concentration of AMPAR protein subunits was quantified using an ELISA assay, while gene expression was analyzed using RT-PCR. The synaptic localization patterns of GluR2 and Ribeye were examined using immunofluorescence and confocal microscopy. Results: Male C57BL/6 mice have a significantly greater basal concentration of the GluR2 subunit than females and more GluR2 puncta per IHC than females. Corticosterone increases the size of Ribeye in males and increases twofold GluR2/Ribeye colocalization in the apical region of females. Conclusions: Exposure of membranous cochleae to corticosterone induces changes consistent with neuroplasticity in the auditory periphery. The observed effect is sex-dependent. Full article

Multiple reduced π-conjugated hydrocarbons exhibit π-electron conjugation modes different from neutral species due to the distinct number of electrons. Herein, we report the generation of a 32 π-electron tetraanion of a derivative of a doubly cyclic π-conjugated system with 28 π-electrons, tetracyclopentatetraphenylene (TCPTP), through an exhaustive reduction with potassium. Although aggregation causes some complications, based on spectroscopic and theoretical investigations, it is revealed that negative charges are located at the outer and inner peripheries, suggesting that the tetraanion adopts a globally delocalized double annulenoid (annulene-within-an-annulene, AWA) mode, with 22 π-electron outer and 10 π-electron inner aromatic perimeters. On the other hand, excess charges of the outer perimeter are mainly located at the apical position of the pentagonal rings, indicating a significant contribution of the cyclopentadienide form. The theoretical analysis of magnetically induced ring current tropicities reveals counter-rotating ring currents at the outer and inner rings, supporting the predominant contribution of the cyclopentadienide form. Full article

The ultrastructure of submandibular gland (SMG) of Bactrian camels was observed by a transmission electron microscope. Routine HE staining, special staining combined with immunohistochemistry, and immunofluorescence techniques were used to study the histochemical characteristics of the submandibular gland and the localisation and distribution characteristics of epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR). HE results showed that the submandibular gland of Bactrian camels was composed of mixed serous and mucinous acini glands. The submandibular striated duct was highly developed and connected with intercalated ducts with larger diameter. Intercalated ducts are shorter and directly connected to acini. In AB-PAS staining, it was observed that the inner wall of striated tube was strongly positive for AB staining. The distribution of the reticular fibres around the follicles and ducts of the submandibular gland is distinct, with collagen fibres distributed mainly in the periphery of the ducts and sparse collagen fibres in the periphery of the acini. Immunohistochemistry and fluorescence show that EGF is strongly positive in striated and intercalated ducts, and EGFR is weakly positive in striated and intercalated ducts. Bactrian camel SMGs secrete more acidic mucins, and EGF and EGFR were mainly secreted and play a role in the pipeline system of SMGs. Full article

Urban expansion encroaches on green spaces and weakens ecosystem services, potentially leading to a trade-off between ecological conditions and socio-economic growth. Effectively coordinating the two elements is essential for achieving sustainable development goals at the urban scale. However, few studies have measured urban–ecological linkage in terms of trade-off. In this study, we propose a framework by linking the degraded ecological conditions and urban land use efficiency from a return on investment perspective. Taking a rapidly expanding city as a case study, we comprehensively quantified urban–ecological conditions in four aspects: urban heat island, flood regulating service, habitat quality, and carbon sequestration. These conditions were assessed on 1 km² grids, along with urban land use efficiency at the same spatial scale. We employed the slack-based measure model to evaluate trade-off efficiency and applied the geo-detector method to identify its driving factors. Our findings reveal that while urban–ecological conditions in Zhengzhou’s periphery degraded over the past two decades, the inner city showed improvement in urban heat island and carbon sequestration. Trade-off efficiency exhibited an overall upward trend during 2000–2020, despite initial declines in some inner city areas. Interaction detection demonstrates significant synergistic effects between pairs of drivers, such as the Normalized Difference Vegetation Index and building height, and the number of patches of green spaces and the patch cohesion index of built-up land, with q-values of 0.298 and 0.137, respectively. In light of the spatiotemporal trend of trade-off efficiency and its drivers, we propose adaptive management strategies. The framework could serve as guidance to assist decision-makers and urban planners in monitoring urban–ecological conditions in the context of urban expansion. Full article

The protected areas (PA) of the Democratic Republic of the Congo serve as vital carbon reservoirs and are crucial for biodiversity conservation and climate regulation. Despite their significance, these areas face escalating rates of deforestation and degradation, often poorly understood at the local level. This study focuses on the dynamics of tropical moist forest (TMF) and the relative importance of the driving factors in the landscape of Kahuzi-Biega National Park (KBNP), one of the country’s prominent PAs. Analyzing annual TMF dynamics from 1990 to 2022 using data classified by Vancutsem and his collaborators in 2021 from Landsat imagery alongside spatial datasets of deforestation and degradation drivers, we employed a comprehensive analytical approach. This included meshing, multi-scale analysis, principal component analysis, zoning, multiple linear regression, and relative importance analysis through bootstrapping. The findings indicate that the grid size considered does not significantly influence TMF dynamics in the KBNP landscape (p-value = 0.67, α = 0.05). The edge and outer zones experienced substantial dynamics, with approximately 30% forest cover loss in both areas, contrasting with the relatively stable TMF cover (~100%) in the inner zone. Fire emerged as the most influential driver, explaining TMF dynamics with a relative importance of approximately 55%, 30%, and 23% in the inner, edge, and outer zones, respectively. This study underscores KBNP’s efficacy in curbing TMF loss but highlights the need for enhanced protection around its periphery. Management efforts should prioritize sustainable land use practices, livelihood improvement, and the establishment of an officially recognized buffer zone. Full article

Myopic eye growth induces mechanical stretch, which can lead to structural and functional retinal alterations. Here, we investigated the effect of lens-induced myopic growth on the distribution of retinal ganglion cells (RGCs), glial fibrillary acidic protein (GFAP) expression and intensity, and peripapillary retinal nerve fiber layer (ppRNFL) thickness in common marmosets (Callithrix jacchus) induced with myopia continuously for six months, using immunohistochemistry and spectral-domain optical coherence tomography. We also explored the relationship between cellular structural parameters and the photopic negative response (PhNR) using full-field electroretinography. Marmosets induced with myopia for six months developed axial myopia, had a thinner ppRNFL, reduced peripapillary ganglion cell (≈20%) and astrocyte density (≈42%), increased panretinal GFAP expression (≈42%) and nasal mid-periphery staining intensity (≈81%) compared to age-matched controls. Greater degrees of myopia and vitreous elongation were associated with reduced peripapillary RGCs and astrocyte density, and increased GFAP expression and intensity. These cellular structural changes did not show a significant relationship with the features of the PhNR, which remained unchanged. The outcomes of this study suggest that myopia induces a reorganization of the peripapillary inner retina at the cellular level that may not result in measurable functional repercussions at this stage of myopia development. Full article

The work concerns the fight against the decline and depopulation in the Inner Peripheries (IPs), a phenomenon taking place globally and throughout Europe, where it has reached an alarming dimension, causing regional disparities that threaten the achievement of Sustainable Development Goals. In Italy, where the term Inner Areas (IAs) is used as a synonym, more than half of the municipalities have the typical problems of IPs. As the latter have a supramunicipal nature, provincial strategic spatial planning is considered adequate to counter these critical issues, assuring a balanced and sustainable development in the social, economic, and environmental domains. To this end, after the state-of-the-art review, this paper proposes a methodology for the construction and mapping of a Decline Index, useful for spatially identifying the most critical municipalities which provide priority strategies to counteract decline through the Provincial Territorial Coordination Plan. The method is based on a multicriteria analysis approach in which Principal Component Analysis (PCA) is integrated and applied to the case study of the Avellino Province in the Campania Region (Italy), which contains many municipalities belonging to IAs. The proposed method is also useful in supporting regional planning and programming for territorial cohesion and sustainable regional growth. Full article