Search Results (10,452)

Named Data Networking (NDN) represents a promising Information-Centric Networking architecture that addresses limitations of traditional host-centric Internet protocols by emphasizing content names rather than host addresses for communication. While NDN offers advantages in content distribution, mobility support, and built-in security features, its stateful forwarding plane introduces significant vulnerabilities, particularly Interest Flooding Attacks (IFAs). These IFA attacks exploit the Pending Interest Table (PIT) by injecting malicious interest packets for non-existent or unsatisfiable content, leading to resource exhaustion and denial-of-service attacks against legitimate users. This survey examines research advances in IFA detection and mitigation from 2013 to 2024, analyzing seven relevant published detection and mitigation strategies to provide current insights into this evolving security challenge. We establish a taxonomy of attack variants, including Fake Interest, Unsatisfiable Interest, Interest Loop, and Collusive models, while examining their operational characteristics and network performance impacts. Our analysis categorizes defense mechanisms into five primary approaches: rate-limiting strategies, PIT management techniques, machine learning and artificial intelligence methods, reputation-based systems, and blockchain-enabled solutions. These approaches are evaluated for their effectiveness, computational requirements, and deployment feasibility. The survey extends to domain-specific implementations in resource-constrained environments, examining adaptations for Internet of Things deployments, wireless sensor networks, and high-mobility vehicular scenarios. Five critical research directions are proposed: adaptive defense mechanisms against sophisticated attackers, privacy-preserving detection techniques, real-time optimization for edge computing environments, standardized evaluation frameworks, and hybrid approaches combining multiple mitigation strategies. Full article

Background/Objectives: Curcumin (CUR) is well known for its therapeutic properties, particularly attributed to its antioxidant and anti-inflammatory effects in managing chronic diseases such as arthritis. While CUR application for biomedical purposes is well known, the phytochemical has several restrictions given its poor water solubility, physicochemical instability, and low bioavailability. These limitations have led to innovative formulations, with nanocarriers emerging as a promising alternative. For this reason, this study aimed to address the potential advantages of associating CUR with nanocarrier systems in managing arthritis through a scoping review. Methods: A systematic literature search of preclinical (in vivo) and clinical studies was performed in PubMed, Scopus, and Web of Science (December 2024). General inclusion criteria include using CUR or natural derivatives in nano-based formulations for arthritis treatment. These elements lead to the question: “What is the impact of the association of CUR or derivatives in nanocarriers in treating arthritis?”. Results: From an initial 536 articles, 34 were selected for further analysis (31 preclinical investigations and three randomized clinical trials). Most studies used pure CUR (25/34), associated with organic (30/34) nanocarrier systems. Remarkably, nanoparticles (16/34) and nanoemulsions (5/34) were emphasized. The formulations were primarily presented in liquid form (23/34) and were generally administered to animal models through intra-articular injection (11/31). Complete Freund’s Adjuvant (CFA) was the most frequently utilized among the various models to induce arthritis-like joint damage. The findings indicate that associating CUR or its derivatives with nanocarrier systems enhances its pharmacological efficacy through controlled release and enhanced solubility, bioavailability, and stability. Moreover, the encapsulation of CUR showed better results in most cases than in its free form. Nonetheless, most studies were restricted to the preclinical model, not providing direct evidence in humans. Additionally, inadequate information and clarity presented considerable challenges for preclinical evidence, which was confirmed by SYRCLE’s bias detection tools. Conclusions: Hence, this scoping review highlights the anti-arthritic effects of CUR nanocarriers as a promising alternative for improved treatment. Full article

“The Internet of Things” is a relatively new idea that refers to objects that can connect to the Internet and exchange data. The Internet of Things (IoT) enables novel interactions between objects and people by interconnecting billions of devices. While there are many IoT-related products, challenges pertaining to their effective implementation, particularly the lack of knowledge and confidence about security, must be addressed. To provide IoT-based enterprises with a platform for efficiency and sustainability, this study aims to identify the critical elements that influence the growth of a successful company integrated with an IoT system. This study proposes a decision support tool that evaluates the influential features of IoT using the Pythagorean Fuzzy and Interval Grey approaches within the Analytical Hierarchy Process (AHP). This study demonstrates that security, value, and connectivity are more critical than telepresence and intelligence indicators. When both strategies are used, market demand and information privacy become significant indicators. Applying the Pythagorean Fuzzy approach enables the identification of sensor networks, authorization, market demand, and data management in terms of importance. The application of the Interval Grey approach underscores the importance of data management, particularly in sensor networks. The indicators that were finally ranked are compared to obtain a good coefficient of agreement. These findings offer practical insights for promoting sustainability in enterprise operations by optimizing IoT infrastructure and decision-making processes. Full article

Background/Objectives: Health education plays a vital role in training health professionals and caregivers, supporting both prevention and the promotion of self-care. In this context, technology serves as a valuable ally by enabling continuous and flexible learning. Among the various domains of health education, nutrition stands out as a key element in the management of Amyotrophic Lateral Sclerosis (ALS), helping to prevent malnutrition and enhance patient well-being. Accordingly, this study aimed to evaluate the effectiveness of the teaching and learning processes within a learning pathway focused on food and nutrition in the context of ALS. Methods: This study adopted a longitudinal, quantitative design. The learning pathway, titled “Food and Nutrition in ALS,” consisted of four self-paced and self-instructional Massive Open Online Courses (MOOCs), offered through the Virtual Learning Environment of the Brazilian Health System (AVASUS). Participants included health professionals, caregivers, and patients from all five regions of Brazil. Participants had the autonomy to complete the courses in any order, with no prerequisites for enrollment. Results: Out of 14,263 participants enrolled nationwide, 182 were included in this study after signing the Informed Consent Form. Of these, 142 (78%) completed at least one course and participated in the educational intervention. A significant increase in knowledge was observed, with mean pre-test scores rising from 7.3 (SD = 1.8) to 9.6 (SD = 0.9) on the post-test across all courses (p < 0.001). Conclusions: The self-instructional, technology-mediated continuing education model proved effective in improving participants’ knowledge about nutrition in ALS. Future studies should explore knowledge retention, behavior change, and the impact of such interventions on clinical outcomes, especially in multidisciplinary care settings. Full article

Pimelea is one of the highly toxic plants in Australia, particularly affecting cattle. It contains simplexin, a potent toxin that can cause Pimelea poisoning (St. George Disease) in livestock. A survey was conducted to assess the current impact of Pimelea on livestock production, pasture systems, and financial losses among agricultural producers. In addition, information was also sought about the environmental conditions that facilitate its growth and the effectiveness of existing management strategies. The survey responses were obtained from producers affected by Pimelea across nine different Local Government Areas, through three States, viz., Queensland, New South Wales, and South Australia. Pimelea was reported to significantly affect animal production, with 97% of producers surveyed acknowledging its detrimental effects. Among livestock, cattle were the most severely affected (94%), when compared to sheep (13%), goats (3%), and horses (3%). The presence of Pimelea was mostly observed in spring (65%) and winter (48%), although 29% of respondents indicated that it could be present all year-round under favorable rainfall conditions. Germination was associated with light to moderate rainfall (52%), while only 24% linked it to heavy rainfall. Pimelea simplex F. Muell. was the most frequently encountered species (71%), followed by Pimelea trichostachya Lindl. (26%). Infestations were reported to occur annually by 47% of producers, with 41% noting occurrences every 2 to 5 years. Financially, producers estimated average annual losses of AUD 67,000, with 50% reporting an average of 26 cattle deaths per year, reaching up to 105 deaths in severe years. Some producers were spending up to AUD 2100 per annum to manage Pimelea. While chemical and physical controls were commonly employed, integrating competitive pastures and alternative livestock, such as sheep and goats, was considered as a potential management strategy. This study reiterates the need for further research on sustainable pasture management practices to reduce Pimelea-related risks to livestock and agricultural production systems. Full article

As medical technology develops and digital demands grow, personal health records (PHRs) are becoming more patient-centered than before based on cloud-based health information exchanges. While enhancing data accessibility and sharing, these systems present privacy and security issues, including data breaches and unauthorized access. We developed a post-quantum, group-oriented encryption scheme using the Crystal-Kyber Key encapsulation mechanism (KEM). Leveraging lattice-based post-quantum cryptography, this scheme ensures quantum resilience and chosen ciphertext attack security for layered cloud PHR environments. It supports four encryption modes: individual, group, subgroup-specific, and authorized subgroup decryption, meeting diverse data access needs. With efficient key management requiring only one private key per user, the developed scheme strengthens the privacy and security of PHRs in a future-proof, flexible, and scalable manner. Full article

Background/Objectives: Clinically significant portal hypertension (CSPH) in cirrhotic patients impacts mortality rates and quality of life. CSPH increases the risk of systemic decompensation and could predispose to the deterioration of portal hypertension (PH)–gastric complications, such as portal hypertensive gastropathy (PHG) and portal hypertensive polyps (PHPs). In the management of CSPH with high-risk varices, endoscopic band ligation (EBL) is effective in preventing variceal bleeding. However, this procedure has several drawbacks, ranging from its inability to treat PH to the potential development of significant PH–gastric complications. The aim of our study is to evaluate endoscopic changes in PHG, PHPs, and gastric varices before and after the obliteration of esophageal varices, highlighting the potential risks of EBL. Methods: We retrospectively evaluated forty-four patients who underwent EBL for esophageal varices in emergency and elective settings, according to Baveno VII guidelines. We assessed the presence and severity of PHG, the status of gastric varices, and the number of PHPs before and after the eradication of esophageal varices. We used Fisher’s exact test and t-tests to compare the endoscopic and clinical-laboratory data statistically. A p-value < 0.05 was considered statistically significant. Results: This study found that after the eradication of varices, there was a significant worsening of PHG in 28 patients (63%) compared to before the procedure (p < 0.05). The condition remained stable in 14 patients (31%). However, it is worth noting that 90% of the patients exhibited severe PHG at baseline. Additionally, the absence of ascites and the non-administration of beta blockers at baseline were independent risk factors for worsening PHG (p < 0.05). Along with the deterioration of PHG, three patients (7%) developed gastric varices, all classified as type 1 gastroesophageal varices, and in two patients (4.5%), PHPs were formed. In particular, out of these two cases, the number of PHPs increased from one to two compared to the baseline. Conclusions: Our study underscores the association of EBL with a general worsening of PH–gastric complications and the protective effect of beta blockers in this context. Despite these promising results, future studies are needed to assess whether the worsening of PH–gastric complications is sustained over time and whether it is associated with a deterioration in clinical outcomes in patients with cirrhosis. Such evidence could help guide a more informed therapeutic decision between EBL and beta blockers. Full article

This study explores the transformative potential of blockchain technology in overhauling conventional housing rental systems. It specifically addresses persistent issues, such as information asymmetry, fraudulent listings, weak Rental Agreements, and data breaches. A comprehensive review of ten academic publications highlights the architectural frameworks, underlying technologies, and myriad benefits of decentralized rental platforms. The intrinsic characteristics of blockchain—immutability, transparency, and decentralization—are pivotal in enhancing the credibility of rental information and proactively preventing fraudulent activities. Smart contracts emerge as a key innovation, enabling the automated execution of Rental Agreements, thereby significantly boosting efficiency and minimizing reliance on intermediaries. Furthermore, Decentralized Identity (DID) solutions offer a robust mechanism for securely managing identities, effectively mitigating risks associated with data leakage, and fostering a more trustworthy environment. The suitability of platforms such as Hyperledger Fabric for developing such sophisticated rental systems is also critically evaluated. Blockchain-based systems promise to dramatically increase market transparency, bolster transaction security, and enhance fraud prevention. They also offer streamlined processes for dispute resolution. Despite these significant advantages, the widespread adoption of blockchain in the rental sector faces several challenges. These include inherent technological complexity, adoption barriers, the need for extensive legal and regulatory adaptation, and critical privacy concerns (e.g., ensuring compliance with GDPR). Furthermore, blockchain scalability limitations and the intricate balance between data immutability and the necessity for occasional data corrections present considerable hurdles. Future research should focus on developing user-friendly DID solutions, enhancing blockchain performance and cost-efficiency, strengthening smart contract security, optimizing the overall user experience, and exploring seamless integration with emerging technologies. While current challenges are undeniable, blockchain technology offers a powerful suite of tools for fundamentally improving the rental market’s efficiency, transparency, and security, exhibiting significant potential to reshape the entire rental ecosystem. Full article

Floods are among the most devastating hydrometeorological natural disasters worldwide, causing massive infrastructure and economic loss in low-lying, flood-prone developing countries like Bangladesh. Effective disaster mitigation relies on organized and detailed flood damage information to facilitate emergency evacuation, coordinate relief distribution, and formulate an effective disaster management policy. Nevertheless, the nation confronts considerable obstacles due to insufficient historical flood damage data and the underdevelopment of near-real-time (NRT) flood monitoring systems. This study addresses this issue by developing a replicable methodology for flood damage assessment and NRT monitoring systems. Using the Google Earth Engine (GEE) platform, we analyzed flood events from 2019 to 2023, integrating geospatial layers such as roads, cropland, etc. Analysis of flood events over the five-year period revealed substantial impacts, with 21.60% of the total area experiencing inundation. This flooding affected 6.92% of cropland and 4.16% of the population. Furthermore, 18.10% of the road network, spanning over 21,000 km within the study area, was also affected. This system has the potential to enhance emergency response capabilities during flood events and inform more effective disaster mitigation policies. Full article

Background: this research presents an integrated approach to enhancing the sustainability of plastic bag supply chains in Indonesia by addressing critical issues related to ineffective post-consumer waste management and low recycling rates. The objective of this study is to develop a combined framework of material flow analysis (MFA) and sustainable supply chain planning to improve demand forecasting and inflow management across the plastic bag lifecycle. Method: the research adopts a quantitative method using the XGBoost algorithm for forecasting and is supported by a polymer-based MFA framework that maps material flows from production to end-of-life stages. Result: the findings indicate that while production processes achieve high efficiency with a yield of 89%, more than 60% of plastic bag waste remains unmanaged after use. Moreover, scenario analysis demonstrates that single interventions are insufficient to achieve circularity targets, whereas integrated strategies (e.g., reducing export volumes, enhancing waste collection, and improving recycling performance) are more effective in increasing recycling rates beyond 35%. Additionally, the study reveals that increasing domestic recycling capacity and minimizing dependency on exports can significantly reduce environmental leakage and strengthen local waste management systems. Conclusions: the study’s novelty lies in demonstrating how machine learning and material flow data can be synergized to inform circular supply chain decisions and regulatory planning. Full article

Adverse drug events (ADEs) significantly impact patient safety and health outcomes. Manual ADE detection from clinical narratives is time-consuming, labor-intensive, and costly. Recent advancements in large language models (LLMs), including transformer-based architectures such as Bidirectional Encoder Representations from Transformers (BERT) and Generative Pretrained Transformer (GPT) series, offer promising methods for automating ADE extraction from clinical data. These models have been applied to various aspects of pharmacovigilance and clinical decision support, demonstrating potential in extracting ADE-related information from real-world clinical data. Additionally, chatbot-assisted systems have been explored as tools in clinical management, aiding in medication adherence, patient engagement, and symptom monitoring. This narrative review synthesizes the current state of LLMs in ADE detection from a clinical perspective, organizing studies into categories such as human-facing decision support tools, immune-related ADE detection, cancer-related and non-cancer-related ADE surveillance, and personalized decision support systems. In total, 39 articles were included in this review. Across domains, LLM-driven methods have demonstrated promising performances, often outperforming traditional approaches. However, critical limitations persist, such as domain-specific variability in model performance, interpretability challenges, data quality and privacy concerns, and infrastructure requirements. By addressing these challenges, LLM-based ADE detection could enhance pharmacovigilance practices, improve patient safety outcomes, and optimize clinical workflows. Full article

The integration of Internet of Things (IoT) systems with social networking concepts has opened new business and social opportunities, particularly by allowing smart objects to autonomously establish social relationships with each other and exchange information. However, these relations must be properly quantified and integrated with trust in order to proliferate the provisioning of IoT composite services. Therefore, this proposed work focuses on quantitatively computing social strength and trust among smart objects in IoT for the purpose of aiding efficient service composition with reasonable accuracy. In particular, we propose a trust-augmented social strength (TASS) management protocol that can cope with the heterogeneity of IoT and demonstrate high scalability and resiliency against various malicious attacks. Afterward, we show how the TASS measurements can be applied to service planning in IoT service composition. Based on the experimental results, we conclude that the proposed protocol is, in fact, capable of exhibiting the above-mentioned characteristics in real-world settings. Full article

This study presents an integrated geospatial framework for assessing the risk to high-speed railway (HSR) infrastructure, combining a persistent scatterer interferometric synthetic aperture radar (PS-InSAR) analysis with multi-criteria decision-making in a geographic information system (GIS) environment. Focusing on the Honam HSR corridor in South Korea, the model incorporates both maximum ground deformation and subsidence velocity to construct a dynamic hazard index. Social vulnerability is quantified using five demographic and infrastructural indicators, and a two-stage analytic hierarchy process (AHP) is applied with dependency correction to mitigate inter-variable redundancy. The resulting high-resolution risk maps highlight spatial mismatches between geotechnical hazards and social exposure, revealing vulnerable segments in Gongju and Iksan that require prioritized maintenance and mitigation. The framework also addresses data limitations by interpolating groundwater levels and estimating train speed using spatial techniques. Designed to be scalable and transferable, this methodology offers a practical decision-support tool for infrastructure managers and policymakers aiming to enhance the resilience of linear transport systems. Full article

In the modern era of smart grids, integrating advanced Geographic Information Systems (GISs) with protection coordination functionalities is pivotal for enhancing the reliability and efficiency of distribution networks. This paper presents an implementation of a web-based distribution network GIS platform that seamlessly integrates distribution system feeder GIS monitoring with the system model file layout, fault current analysis, and coordination simulation functions. The system can provide scalable and accessible solutions for power utilities, ensuring that protective devices operate in a coordinated manner to minimize outage impacts and improve service restoration times. The proposed GIS platform has demonstrated significant improvements in fault management and relay coordination through extensive simulation and field testing. This research advances the capabilities of distribution network management and sets a foundation for future enhancements in smart grid technology. Full article

Smart cities are technologically advanced urban environments where interconnected systems and data-driven technologies enhance public service delivery and quality of life. These cities rely on information and communication technologies, the Internet of Things, big data, cloud computing, and other Industry 4.0 tools to support efficient city management and foster citizen engagement. Often referred to as digital cities, they integrate intelligent infrastructures and real-time data analytics to improve mobility, security, and sustainability. Ubiquitous sensors, paired with Artificial Intelligence, enable cities to monitor infrastructure, respond to residents’ needs, and optimize urban conditions dynamically. Given the increasing significance of Industry 4.0 in urban development, this study adopts a bibliometric approach to systematically review the application of these technologies within smart cities. Utilizing major academic databases such as Scopus and Web of Science the research aims to identify the primary Industry 4.0 technologies implemented in smart cities, assess their impact on infrastructure, economic systems, and urban communities, and explore the challenges and benefits associated with their integration. The bibliometric analysis included publications from 2016 to 2023, since the emergence of urban researchers’ interest in the technologies of the new industrial revolution. The task is to contribute to a deeper understanding of how smart cities evolve through the adoption of advanced technological frameworks. Research indicates that IoT and AI are the most commonly used tools in urban spaces, particularly in smart mobility and smart environments. Full article