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Keywords = health indicator construction

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14 pages, 649 KiB  
Article
Investigating the Moderating Effect of Attitudes Toward One’s Own Aging on the Association Between Body Mass Index and Executive Function in Older Adults
by Akihiko Iwahara, Taketoshi Hatta, Reiko Nakayama, Takashi Miyawaki, Seiji Sakate, Junko Hatta and Takeshi Hatta
Geriatrics 2025, 10(4), 105; https://doi.org/10.3390/geriatrics10040105 - 6 Aug 2025
Abstract
Background: This cross-sectional study examined the association between body mass index (BMI) and executive function (EF) in older adults, with a focus on the moderating role of attitudes toward own aging (ATOA). Method: A total of 431 community-dwelling elderly individuals from Yakumo Town [...] Read more.
Background: This cross-sectional study examined the association between body mass index (BMI) and executive function (EF) in older adults, with a focus on the moderating role of attitudes toward own aging (ATOA). Method: A total of 431 community-dwelling elderly individuals from Yakumo Town and Kyoto City, Japan, participated between 2023 and 2024. EF was assessed using the Digit Cancellation Test (D-CAT), and ATOA was measured via a validated subscale of the Philadelphia Geriatric Center Morale Scale. Results: Multiple linear regression analyses adjusted for demographic and health covariates revealed a significant interaction between BMI and ATOA in the younger-old cohort. Specifically, higher BMI was associated with lower executive function only in individuals with lower ATOA scores. No such association was observed in those with more positive views on aging. Conclusions: These results indicate that positive psychological constructs, particularly favorable self-perceptions of aging, may serve as protective factors against the detrimental cognitive consequences of increased body mass index in younger-old populations. Full article
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25 pages, 4751 KiB  
Article
Dynamic Evolution and Resilience Enhancement of the Urban Tourism Ecological Health Network: A Case Study in Shanghai, China
by Man Wei and Tai Huang
Systems 2025, 13(8), 654; https://doi.org/10.3390/systems13080654 - 2 Aug 2025
Viewed by 234
Abstract
Urban tourism has evolved into a complex adaptive system, where unregulated expansion disrupts the ecological balance and intensifies resource stress. Understanding the dynamic evolution and resilience mechanisms of the tourism ecological health network (TEHN) is essential for supporting sustainable urban tourism as a [...] Read more.
Urban tourism has evolved into a complex adaptive system, where unregulated expansion disrupts the ecological balance and intensifies resource stress. Understanding the dynamic evolution and resilience mechanisms of the tourism ecological health network (TEHN) is essential for supporting sustainable urban tourism as a coupled human–natural system. Using Shanghai as a case study, we applied the “vigor–organization–resilience–services” (VORS) framework to evaluate ecosystem health, which served as a constraint for constructing the TEHN, using the minimum cumulative resistance (MCR) model for the period from 2001 to 2023. A resilience framework integrating structural and functional dimensions was further developed to assess spatiotemporal evolution and guide targeted enhancement strategies. The results indicated that as ecosystem health degraded, particularly in peripheral areas, the urban TEHN in Shanghai shifted from a dispersed to a centralized structure, with limited connectivity in the periphery. The resilience of the TEHN continued to grow, with structural resilience remaining at a high level, while functional resilience still required enhancement. Specifically, the low integration and limited choice between the tourism network and the transportation system hindered tourists from selecting routes with higher ecosystem health indices. Enhancing functional resilience, while sustaining structural resilience, is essential for transforming the TEHN into a multi-centered, multi-level system that promotes efficient connectivity, ecological sustainability, and long-term adaptability. The results contribute to a systems-level understanding of tourism–ecology interactions and support the development of adaptive strategies for balancing network efficiency and environmental integrity. Full article
(This article belongs to the Section Complex Systems and Cybernetics)
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16 pages, 291 KiB  
Article
General and Specific Social Trust as Predictors of Depressive Symptoms: Evidence from Post-Crisis Iceland
by Haukur Freyr Gylfason
World 2025, 6(3), 107; https://doi.org/10.3390/world6030107 - 1 Aug 2025
Viewed by 257
Abstract
Social trust has been linked to the development and severity of depression, but trust is a complex, multidimensional construct. This study examines the extent to which two distinct forms of trust, general trust and specific trust, predict depressive symptoms. Drawing on longitudinal data [...] Read more.
Social trust has been linked to the development and severity of depression, but trust is a complex, multidimensional construct. This study examines the extent to which two distinct forms of trust, general trust and specific trust, predict depressive symptoms. Drawing on longitudinal data from the Directorate of Health’s national surveys conducted in 2007 and 2009, the analysis includes responses from 3211 Icelanders selected through a stratified random sample. Depressive symptoms were assessed using the Depression, Anxiety, and Stress Scale (DASS), while specific trust captured trust in close relationships, and general trust measured broader perceptions of trustworthiness in others. The two forms of trust together explained 7.6% of the variance in depressive symptoms, with specific trust contributing a substantially greater share. Both remained significant predictors after controlling for prior depression and physical health. These findings highlight the protective role of specific trust and suggest that general trust, an indicator of broader social capital, may also help buffer against depression. The results underscore the relevance of trust as a public health resource and support continued research into social determinants of mental health in Iceland. Full article
23 pages, 3481 KiB  
Article
Research on Adaptive Identification Technology for Rolling Bearing Performance Degradation Based on Vibration–Temperature Fusion
by Zhenghui Li, Lixia Ying, Liwei Zhan, Shi Zhuo, Hui Li and Xiaofeng Bai
Sensors 2025, 25(15), 4707; https://doi.org/10.3390/s25154707 - 30 Jul 2025
Viewed by 365
Abstract
To address the issue of low accuracy in identifying the transition states of rolling bearing performance degradation when relying solely on vibration signals, this study proposed a vibration–temperature fusion-based adaptive method for bearing performance degradation assessments. First, a multidimensional time–frequency feature set was [...] Read more.
To address the issue of low accuracy in identifying the transition states of rolling bearing performance degradation when relying solely on vibration signals, this study proposed a vibration–temperature fusion-based adaptive method for bearing performance degradation assessments. First, a multidimensional time–frequency feature set was constructed by integrating vibration acceleration and temperature signals. Second, a novel composite sensitivity index (CSI) was introduced, incorporating the trend persistence, monotonicity, and signal complexity to perform preliminary feature screening. Mutual information clustering and regularized entropy weight optimization were then combined to reselect highly sensitive parameters from the initially screened features. Subsequently, an adaptive feature fusion method based on auto-associative kernel regression (AFF-AAKR) was introduced to compress the data in the spatial dimension while enhancing the degradation trend characterization capability of the health indicator (HI) through a temporal residual analysis. Furthermore, the entropy weight method was employed to quantify the information entropy differences between the vibration and temperature signals, enabling dynamic weight allocation to construct a comprehensive HI. Finally, a dual-criteria adaptive bottom-up merging algorithm (DC-ABUM) was proposed, which achieves bearing life-stage identification through error threshold constraints and the adaptive optimization of segmentation quantities. The experimental results demonstrated that the proposed method outperformed traditional vibration-based life-stage identification approaches. Full article
(This article belongs to the Special Issue Fault Diagnosis Based on Sensing and Control Systems)
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20 pages, 3903 KiB  
Article
Void Detection of Airport Concrete Pavement Slabs Based on Vibration Response Under Moving Load
by Xiang Wang, Ziliang Ma, Xing Hu, Xinyuan Cao and Qiao Dong
Sensors 2025, 25(15), 4703; https://doi.org/10.3390/s25154703 - 30 Jul 2025
Viewed by 247
Abstract
This study proposes a vibration-based approach for detecting and quantifying sub-slab corner voids in airport cement concrete pavement. Scaled down slab models were constructed and subjected to controlled moving load simulations. Acceleration signals were collected and analyzed to extract time–frequency domain features, including [...] Read more.
This study proposes a vibration-based approach for detecting and quantifying sub-slab corner voids in airport cement concrete pavement. Scaled down slab models were constructed and subjected to controlled moving load simulations. Acceleration signals were collected and analyzed to extract time–frequency domain features, including power spectral density (PSD), skewness, and frequency center. A finite element model incorporating contact and nonlinear constitutive relationships was established to simulate structural response under different void conditions. Based on the simulated dataset, a random forest (RF) model was developed to estimate void size using selected spectral energy indicators and geometric parameters. The results revealed that the RF model achieved strong predictive performance, with a high correlation between key features and void characteristics. This work demonstrates the feasibility of integrating simulation analysis, signal feature extraction, and machine learning to support intelligent diagnostics of concrete pavement health. Full article
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24 pages, 292 KiB  
Article
Golden Years and Companion Animals: Investigating How the Human–Animal Bond Shapes Pet Wellness in Later Life from the Owner’s Perception
by Amira A. Goma and Emily Kieson
Vet. Sci. 2025, 12(8), 713; https://doi.org/10.3390/vetsci12080713 - 29 Jul 2025
Viewed by 338
Abstract
Most research studies have investigated the impact of pet ownership on the mental and physical well-being of elderly populations, supporting the beneficial effect that pets have on their owners. However, few researchers focused on the well-being of both owner and pet. The present [...] Read more.
Most research studies have investigated the impact of pet ownership on the mental and physical well-being of elderly populations, supporting the beneficial effect that pets have on their owners. However, few researchers focused on the well-being of both owner and pet. The present study aimed to explore the well-being of pets owned by elderly individuals using an owner assessment tool and the relationship between elderly characteristics and the pet’s health-related quality of life based on the owner’s assessment of their pet’s well-being. Sixty elderly pet owners who made regular visits to veterinary clinics were selected to complete an electronic questionnaire about their pet’s health-related quality of life. The results identified a high agreement percentage on positive indicators related to the pet’s well-being such as “My pet wants to play and My pet responds to my presence” in the happiness domain, “My pet has more good days than bad days” in mental status, “My pet moves normally” in physical status and “My pet keeps him/herself clean” in hygiene which also resulted in a positive relationship with elderly age. Marital status influenced their responses to “My pet responds to my presence and My pet is as active as he/she has been”. The results also support the use of the applied questionnaire to help identify variables that contribute to a pet’s health-related quality of life. The correlation matrix revealed statistically significant positive associations (p < 0.001) among positively phrased items across all domains, as well as among negatively phrased items. These consistent alignments between direct and between reversed items suggest directional coherence and help mitigate potential response bias. Furthermore, the replication of these patterns across multiple domains reinforces the interpretation that the instrument captures a unified construct of pet well-being, In conclusion, based on subjective evaluation of pet-owner relationships, the ownership of pets by elderly individuals could be mutually beneficial to both elderly owners and their pets. Full article
22 pages, 12611 KiB  
Article
Banana Fusarium Wilt Recognition Based on UAV Multi-Spectral Imagery and Automatically Constructed Enhanced Features
by Ye Su, Longlong Zhao, Huichun Ye, Wenjiang Huang, Xiaoli Li, Hongzhong Li, Jinsong Chen, Weiping Kong and Biyao Zhang
Agronomy 2025, 15(8), 1837; https://doi.org/10.3390/agronomy15081837 - 29 Jul 2025
Viewed by 170
Abstract
Banana Fusarium wilt (BFW, also known as Panama disease) is a highly infectious and destructive disease that threatens global banana production, requiring early recognition for timely prevention and control. Current monitoring methods primarily rely on continuous variable features—such as band reflectances (BRs) and [...] Read more.
Banana Fusarium wilt (BFW, also known as Panama disease) is a highly infectious and destructive disease that threatens global banana production, requiring early recognition for timely prevention and control. Current monitoring methods primarily rely on continuous variable features—such as band reflectances (BRs) and vegetation indices (VIs)—collectively referred to as basic features (BFs)—which are prone to noise during the early stages of infection and struggle to capture subtle spectral variations, thus limiting the recognition accuracy. To address this limitation, this study proposes a discretized enhanced feature (EF) construction method, the automated kernel density segmentation-based feature construction algorithm (AutoKDFC). By analyzing the differences in the kernel density distributions between healthy and diseased samples, the AutoKDFC automatically determines the optimal segmentation threshold, converting continuous BFs into binary features with higher discriminative power for early-stage recognition. Using UAV-based multi-spectral imagery, BFW recognition models are developed and tested with the random forest (RF), support vector machine (SVM), and Gaussian naïve Bayes (GNB) algorithms. The results show that EFs exhibit significantly stronger correlations with BFW’s presence than original BFs. Feature importance analysis via RF further confirms that EFs contribute more to the model performance, with VI-derived features outperforming BR-based ones. The integration of EFs results in average performance gains of 0.88%, 2.61%, and 3.07% for RF, SVM, and GNB, respectively, with SVM achieving the best performance, averaging over 90%. Additionally, the generated BFW distribution map closely aligns with ground observations and captures spectral changes linked to disease progression, validating the method’s practical utility. Overall, the proposed AutoKDFC method demonstrates high effectiveness and generalizability for BFW recognition. Its core concept of “automatic feature enhancement” has strong potential for broader applications in crop disease monitoring and supports the development of intelligent early warning systems in plant health management. Full article
(This article belongs to the Section Pest and Disease Management)
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25 pages, 3167 KiB  
Article
A Sustainability-Oriented Assessment of Noise Impacts on University Dormitories: Field Measurements, Student Survey, and Modeling Analysis
by Xiaoying Wen, Shikang Zhou, Kainan Zhang, Jianmin Wang and Dongye Zhao
Sustainability 2025, 17(15), 6845; https://doi.org/10.3390/su17156845 - 28 Jul 2025
Viewed by 336
Abstract
Ensuring a sustainable and healthy human environment in university dormitories is essential for students’ learning, living, and overall health and well-being. To address this need, we carried out a series of systematic field measurements of the noise levels at 30 dormitories in three [...] Read more.
Ensuring a sustainable and healthy human environment in university dormitories is essential for students’ learning, living, and overall health and well-being. To address this need, we carried out a series of systematic field measurements of the noise levels at 30 dormitories in three representative major urban universities in a major provincial capital city in China and designed and implemented a comprehensive questionnaire and surveyed 1005 students about their perceptions of their acoustic environment. We proposed and applied a sustainability–health-oriented, multidimensional assessment framework to assess the acoustic environment of the dormitories and student responses to natural sound, technological sounds, and human-made sounds. Using the Structural Equation Modeling (SEM) approach combined with the field measurements and student surveys, we identified three categories and six factors on student health and well-being for assessing the acoustic environment of university dormitories. The field data indicated that noise levels at most of the measurement points exceeded the recommended or regulatory thresholds. Higher noise impacts were observed in early mornings and evenings, primarily due to traffic noise and indoor activities. Natural sounds (e.g., wind, birdsong, water flow) were highly valued by students for their positive effect on the students’ pleasantness and satisfaction. Conversely, human and technological sounds (traffic noise, construction noise, and indoor noise from student activities) were deemed highly disturbing. Gender differences were evident in the assessment of the acoustic environment, with male students generally reporting higher levels of the pleasantness and preference for natural sounds compared to female students. Educational backgrounds showed no significant influence on sound perceptions. The findings highlight the need for providing actionable guidelines for dormitory ecological design, such as integrating vertical greening in dormitory design, water features, and biodiversity planting to introduce natural soundscapes, in parallel with developing campus activity standards and lifestyle during noise-sensitive periods. The multidimensional assessment framework will drive a sustainable human–ecology–sound symbiosis in university dormitories, and the category and factor scales to be employed and actions to improve the level of student health and well-being, thus, providing a reference for both research and practice for sustainable cities and communities. Full article
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26 pages, 11912 KiB  
Article
Multi-Dimensional Estimation of Leaf Loss Rate from Larch Caterpillar Under Insect Pest Stress Using UAV-Based Multi-Source Remote Sensing
by He-Ya Sa, Xiaojun Huang, Li Ling, Debao Zhou, Junsheng Zhang, Gang Bao, Siqin Tong, Yuhai Bao, Dashzebeg Ganbat, Mungunkhuyag Ariunaa, Dorjsuren Altanchimeg and Davaadorj Enkhnasan
Drones 2025, 9(8), 529; https://doi.org/10.3390/drones9080529 - 28 Jul 2025
Viewed by 325
Abstract
Leaf loss caused by pest infestations poses a serious threat to forest health. The leaf loss rate (LLR) refers to the percentage of the overall tree-crown leaf loss per unit area and is an important indicator for evaluating forest health. Therefore, rapid and [...] Read more.
Leaf loss caused by pest infestations poses a serious threat to forest health. The leaf loss rate (LLR) refers to the percentage of the overall tree-crown leaf loss per unit area and is an important indicator for evaluating forest health. Therefore, rapid and accurate acquisition of the LLR via remote sensing monitoring is crucial. This study is based on drone hyperspectral and LiDAR data as well as ground survey data, calculating hyperspectral indices (HSI), multispectral indices (MSI), and LiDAR indices (LI). It employs Savitzky–Golay (S–G) smoothing with different window sizes (W) and polynomial orders (P) combined with recursive feature elimination (RFE) to select sensitive features. Using Random Forest Regression (RFR) and Convolutional Neural Network Regression (CNNR) to construct a multidimensional (horizontal and vertical) estimation model for LLR, combined with LiDAR point cloud data, achieved a three-dimensional visualization of the leaf loss rate of trees. The results of the study showed: (1) The optimal combination of HSI and MSI was determined to be W11P3, and the LI was W5P2. (2) The optimal combination of the number of sensitive features extracted by the RFE algorithm was 13 HSI, 16 MSI, and hierarchical LI (2 in layer I, 9 in layer II, and 11 in layer III). (3) In terms of the horizontal estimation of the defoliation rate, the model performance index of the CNNRHSI model (MPI = 0.9383) was significantly better than that of RFRMSI (MPI = 0.8817), indicating that the continuous bands of hyperspectral could better monitor the subtle changes of LLR. (4) The I-CNNRHSI+LI, II-CNNRHSI+LI, and III-CNNRHSI+LI vertical estimation models were constructed by combining the CNNRHSI model with the best accuracy and the LI sensitive to different vertical levels, respectively, and their MPIs reached more than 0.8, indicating that the LLR estimation of different vertical levels had high accuracy. According to the model, the pixel-level LLR of the sample tree was estimated, and the three-dimensional display of the LLR for forest trees under the pest stress of larch caterpillars was generated, providing a high-precision research scheme for LLR estimation under pest stress. Full article
(This article belongs to the Section Drones in Agriculture and Forestry)
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24 pages, 622 KiB  
Article
The Differential Impact of Human Capital on Social Integration Among Rural–Urban and Urban–Urban Migrants in China
by Tao Xu and Jiyan Ren
Urban Sci. 2025, 9(8), 292; https://doi.org/10.3390/urbansci9080292 - 25 Jul 2025
Viewed by 554
Abstract
Differences exist between rural–urban migrants and urban–urban migrants in terms of human capital’s accumulation and pathways of social integration, yet few studies have systematically compared these distinctions. Based on the CMDS2017 survey data, this study constructed a comprehensive social integration index across four [...] Read more.
Differences exist between rural–urban migrants and urban–urban migrants in terms of human capital’s accumulation and pathways of social integration, yet few studies have systematically compared these distinctions. Based on the CMDS2017 survey data, this study constructed a comprehensive social integration index across four dimensions—economic integration, behavioral adaptation, identity recognition, and psychological assimilation—to analyze the influencing factors and decompose the disparities in social integration levels between the two groups from a human capital perspective. Using Oaxaca mean decomposition and Machado–Mata (MM) quantile decomposition, the results indicated that urban–urban migrants exhibited higher social integration levels than rural–urban migrants, with human capital significantly influencing integration outcomes. Better education, health status, longer migration duration, and more work experience positively enhanced migrants’ social integration. Human capital accounted for 38.35% of the social integration gap between the two groups, while coefficient differences were the primary driver of disparities. The returns to education diminish at higher integration levels, suggesting education played a stronger role for those with lower integration. The social integration gap between the two groups followed an inverted U-shaped trend, with smaller disparities at higher quantiles. As integration levels rose, characteristic differences declined continuously, indicating convergence toward homogeneity among high-integration migrants. These research findings indicated that the improvement in the social integration level of migrants still requires continuous investment in cultivating the human capital of migrants. Full article
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21 pages, 2406 KiB  
Article
Determining Factors for the Diagnosis of Multidimensional Depression and Its Representation: A Composite Indicator Based on Linear Discriminant Analysis
by Matheus Pereira Libório, Angélica C. G. Santos, Marcos Flávio Silveira Vasconcelos D’angelo, Hasheem Mannan, Cristiane Neri Nobre, Ariane Carla Barbosa da Silva, Petr Iakovlevitch Ekel and Allysson Steve Mota Lacerda
Appl. Sci. 2025, 15(15), 8275; https://doi.org/10.3390/app15158275 - 25 Jul 2025
Viewed by 273
Abstract
This study proposes a novel approach to constructing composite indicators, utilizing discriminant analysis to identify the determining factors for the diagnosis of multidimensional depression and to provide an index that represents the multidimensionality of this construct. By focusing solely on factors that significantly [...] Read more.
This study proposes a novel approach to constructing composite indicators, utilizing discriminant analysis to identify the determining factors for the diagnosis of multidimensional depression and to provide an index that represents the multidimensionality of this construct. By focusing solely on factors that significantly correlate with the diagnosis of multidimensional depression, this method provides a more precise and objective representation of the problem. The application of the method to the 2019 Brazilian Health Survey data demonstrated its effectiveness, resulting in a composite indicator that separates individuals who self-declare as having depression from individuals who self-declare as not having depression. The results highlight individuals who have a limiting chronic condition, high levels of education, less support from friends and family, perform unhealthy work, and are male. In contrast, individuals with the opposite characteristics are associated with a negative multidimensional depression diagnosis. The proposed composite indicator not only improves the measurement accuracy but also offers a new means of visualizing and understanding the multidimensional nature of depression diagnosis, providing valuable information for the formulation of targeted public health policies aimed at reducing the time for which people show symptoms of depression. Full article
(This article belongs to the Special Issue State-of-the-Art of Intelligent Decision Support Systems)
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23 pages, 1593 KiB  
Article
Natural Ventilation Technique of uNVeF in Urban Residential Unit Through a Case Study
by Ming-Lun Alan Fong and Wai-Kit Chan
Urban Sci. 2025, 9(8), 291; https://doi.org/10.3390/urbansci9080291 - 25 Jul 2025
Viewed by 892
Abstract
The present study was motivated by the need to enhance indoor air quality and reduce airborne disease transmission in dense urban environments where high-rise residential buildings face challenges in achieving effective natural ventilation. The problem lies in the lack of scalable and convenient [...] Read more.
The present study was motivated by the need to enhance indoor air quality and reduce airborne disease transmission in dense urban environments where high-rise residential buildings face challenges in achieving effective natural ventilation. The problem lies in the lack of scalable and convenient tools to optimize natural ventilation rate, particularly in urban settings with varying building heights. To address this, the scientific technique developed with an innovative metric, the urbanized natural ventilation effectiveness factor (uNVeF), integrates regression analysis of wind direction, velocity, air change rate per hour (ACH), window configurations, and building height to quantify ventilation efficiency. By employing a field measurement methodology, the measurements were conducted across 25 window-opening scenarios in a 13.9 m2 residential unit on the 35/F of a Hong Kong public housing building, supplemented by the Hellman Exponential Law with a site-specific friction coefficient (0.2907, R2 = 0.9232) to estimate the lower floor natural ventilation rate. The results confirm compliance with Hong Kong’s statutory 1.5 ACH requirement (Practice Note for Authorized Persons, Registered Structural Engineers, and Registered Geotechnical Engineers) and achieving a peak ACH at a uNVeF of 0.953 with 75% window opening. The results also revealed that lower floors can maintain 1.5 ACH with adjusted window configurations. Using the Wells–Riley model, the estimation results indicated significant airborne disease infection risk reductions of 96.1% at 35/F and 93.4% at 1/F compared to the 1.5 ACH baseline which demonstrates a strong correlation between ACH, uNVeF and infection risks. The uNVeF framework offers a practical approach to optimize natural ventilation and provides actionable guidelines, together with future research on the scope of validity to refine this technique for residents and developers. The implications in the building industry include setting up sustainable design standards, enhancing public health resilience, supporting policy frameworks for energy-efficient urban planning, and potentially driving innovation in high-rise residential construction and retrofitting globally. Full article
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14 pages, 2935 KiB  
Article
Deep Learning-Based Differentiation of Vertebral Body Lesions on Magnetic Resonance Imaging
by Hüseyin Er, Murat Tören, Berkutay Asan, Esat Kaba and Mehmet Beyazal
Diagnostics 2025, 15(15), 1862; https://doi.org/10.3390/diagnostics15151862 - 24 Jul 2025
Viewed by 368
Abstract
Objectives: Spinal diseases are commonly encountered health problems with a wide spectrum. In addition to degenerative changes, other common spinal pathologies include metastases and compression fractures. Benign tumors like hemangiomas and infections such as spondylodiscitis are also frequently observed. Although magnetic resonance imaging [...] Read more.
Objectives: Spinal diseases are commonly encountered health problems with a wide spectrum. In addition to degenerative changes, other common spinal pathologies include metastases and compression fractures. Benign tumors like hemangiomas and infections such as spondylodiscitis are also frequently observed. Although magnetic resonance imaging (MRI) is considered the gold standard in diagnostic imaging, the morphological similarities of lesions can pose significant challenges in differential diagnoses. In recent years, the use of artificial intelligence applications in medical imaging has become increasingly widespread. In this study, we aim to detect and classify vertebral body lesions using the YOLO-v8 (You Only Look Once, version 8) deep learning architecture. Materials and Methods: This study included MRI data from 235 patients with vertebral body lesions. The dataset comprised sagittal T1- and T2-weighted sequences. The diagnostic categories consisted of acute compression fractures, metastases, hemangiomas, atypical hemangiomas, and spondylodiscitis. For automated detection and classification of vertebral lesions, the YOLOv8 deep learning model was employed. Following image standardization and data augmentation, a total of 4179 images were generated. The dataset was randomly split into training (80%) and validation (20%) subsets. Additionally, an independent test set was constructed using MRI images from 54 patients who were not included in the training or validation phases to evaluate the model’s performance. Results: In the test, the YOLOv8 model achieved classification accuracies of 0.84 and 0.85 for T1- and T2-weighted MRI sequences, respectively. Among the diagnostic categories, spondylodiscitis had the highest accuracy in the T1 dataset (0.94), while acute compression fractures were most accurately detected in the T2 dataset (0.93). Hemangiomas exhibited the lowest classification accuracy in both modalities (0.73). The F1 scores were calculated as 0.83 for T1-weighted and 0.82 for T2-weighted sequences at optimal confidence thresholds. The model’s mean average precision (mAP) 0.5 values were 0.82 for T1 and 0.86 for T2 datasets, indicating high precision in lesion detection. Conclusions: The YOLO-v8 deep learning model we used demonstrates effective performance in distinguishing vertebral body metastases from different groups of benign pathologies. Full article
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13 pages, 2372 KiB  
Article
PTEN and ERG Biomarkers as Predictors of Biochemical Recurrence Risk in Patients Undergoing Radical Prostatectomy
by Mihnea Bogdan Borz, Bogdan Fetica, Maximilian Cosma Gliga, Tamas-Csaba Sipos, Bogdan Adrian Buhas and Vlad Horia Schitcu
Diseases 2025, 13(8), 235; https://doi.org/10.3390/diseases13080235 - 24 Jul 2025
Viewed by 302
Abstract
Background/Objectives: Prostate cancer (PCa) remains a major global health issue, associated with significant mortality and morbidity. Despite advances in diagnosis and treatment, predicting biochemical recurrence (BCR) after radical prostatectomy remains challenging, highlighting the need for reliable biomarkers to guide prognosis and therapy. [...] Read more.
Background/Objectives: Prostate cancer (PCa) remains a major global health issue, associated with significant mortality and morbidity. Despite advances in diagnosis and treatment, predicting biochemical recurrence (BCR) after radical prostatectomy remains challenging, highlighting the need for reliable biomarkers to guide prognosis and therapy. The study aimed to evaluate the prognostic significance of the PTEN and ERG biomarkers in predicting BCR and tumor progression in PCa patients who underwent radical prostatectomy. Methods: This study consisted of a cohort of 91 patients with localized PCa who underwent radical prostatectomy between 2016 and 2022. From this cohort, 77 patients were selected for final analysis. Tissue microarrays (TMAs) were constructed from paraffin blocks, and immunohistochemical (IHC) staining for PTEN and ERG was performed using specific antibodies on the Ventana BenchMark ULTRA system (Roche Diagnostics, Indianapolis, IN, USA). Stained sections were evaluated and correlated with clinical and pathological data. Results: PTEN expression showed a significant negative correlation with BCR (r = −0.301, p = 0.014), indicating that reduced PTEN expression is associated with increased recurrence risk. PTEN was not significantly linked to PSA levels, tumor stage, or lymph node involvement. ERG expression correlated positively with advanced pathological tumor stage (r = 0.315, p = 0.005) but was not associated with BCR or other clinical parameters. Conclusions: PTEN appears to be a valuable prognostic marker for recurrence in PCa, while ERG may indicate tumor progression. These findings support the potential integration of PTEN and ERG into clinical practice to enhance risk stratification and personalized treatment, warranting further validation in larger patient cohorts. Full article
(This article belongs to the Section Oncology)
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18 pages, 1169 KiB  
Article
Multi-Dimensional Analysis of Quality-Related Traits Affecting the Taste of Main Cultivated Japonica Rice Varieties in Northern China
by Hongwei Yang, Liying Zhang, Xiangquan Gao, Shi Han, Zuobin Ma and Lili Wang
Agronomy 2025, 15(8), 1757; https://doi.org/10.3390/agronomy15081757 - 22 Jul 2025
Viewed by 325
Abstract
The quality of rice, one of the most important food crops in the world, is directly related to people’s dietary experience and nutritional health. With the improvement in living standards, consumer requirements for the taste quality of rice are becoming increasingly strict. Japonica [...] Read more.
The quality of rice, one of the most important food crops in the world, is directly related to people’s dietary experience and nutritional health. With the improvement in living standards, consumer requirements for the taste quality of rice are becoming increasingly strict. Japonica rice occupies an important position in rice production due to its rich genetic diversity and excellent agronomic characteristics. In this study, LJ433, JY653, LJ218, LJ177, LY66, and LX21, which are mainly popularized in northern China and have different taste values, were selected as the experimental subjects, and YJ219, which won the gold award in the third China high-quality rice variety taste quality evaluation, was taken as the control (CK). Low-field nuclear magnetic resonance and spectral analysis were adopted as the main detection techniques. The effects of free water (peak area increased by 13.24–86.68% when p < 0.05), bound water, appearance characteristics (such as chalkiness, which decreased by 18.48–86.48%), and chemical composition (amylose content decreased by 3.76–26.47%) on the taste value of rice were systematically analyzed, and a multi-dimensional “appearance–palatability–nutrition” evaluation system was constructed. The experimental results indicated that increasing the free water content, reducing the chalkiness and chemical component content could significantly improve the taste value of rice (p < 0.05). The results of this research provide a theoretical basis for breeding new high-yield and high-quality rice varieties and have guiding significance for the practice of rice planting and processing. Full article
(This article belongs to the Section Plant-Crop Biology and Biochemistry)
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