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12 pages, 12870 KiB  
Article
Direct Glass-to-Metal Welding by Femtosecond Laser Pulse Bursts: I, Conditions for Successful Welding with a Gap
by Qingfeng Li, Gabor Matthäus, David Sohr and Stefan Nolte
Nanomaterials 2025, 15(15), 1202; https://doi.org/10.3390/nano15151202 - 6 Aug 2025
Abstract
We report on the welding of optical borosilicate glass to an unpolished copper substrate (surface Ra of 0.27 µm and Rz of 1.89 µm) using bursts of femtosecond laser pulses. The present paper puts forth the hypothesis that glass–metal welding with a gap [...] Read more.
We report on the welding of optical borosilicate glass to an unpolished copper substrate (surface Ra of 0.27 µm and Rz of 1.89 µm) using bursts of femtosecond laser pulses. The present paper puts forth the hypothesis that glass–metal welding with a gap is contingent upon the ejection of molten jets of glass. We have ascertained the impact of pulse energy and focal position on weldability. This finding serves to substantiate our initial hypothesis and provides a framework for understanding the conditions under which this hypothesis is applicable. Under optimal conditions, but without the assistance of any clamping system, our welded samples maintained a breaking resistance of up to 10.9 MPa. Full article
(This article belongs to the Special Issue Ultrafast Laser Micro-Nano Welding: From Principles to Applications)
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14 pages, 1508 KiB  
Article
The Effect of the Structure of Aromatic Diamine on High-Performance Epoxy Resins
by Yan Zhou, Weibo Liu, Yu Feng, Pengfei Shi, Liqiang Wan, Xufeng Hao, Farong Huang, Jianhua Qian and Zuozhen Liu
J. Compos. Sci. 2025, 9(8), 416; https://doi.org/10.3390/jcs9080416 - 4 Aug 2025
Abstract
To study the influence of curing agent structure on the properties of epoxy resin, four types of aromatic diamines with the structure of diphenyl methane (4,4′-methylenedianiline (MDA), 4,4′-methylenebis(2-ethylaniline) (MOEA), 4,4′-methylenebis(2-chloroaniline) (MOCA), and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) (MCDEA)) and a high-performance epoxy resin, 3-(oxiran-2-ylmethoxy)-N,N-bis(oxiran-2-ylmethyl)aniline (AFG-90MH), were used [...] Read more.
To study the influence of curing agent structure on the properties of epoxy resin, four types of aromatic diamines with the structure of diphenyl methane (4,4′-methylenedianiline (MDA), 4,4′-methylenebis(2-ethylaniline) (MOEA), 4,4′-methylenebis(2-chloroaniline) (MOCA), and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) (MCDEA)) and a high-performance epoxy resin, 3-(oxiran-2-ylmethoxy)-N,N-bis(oxiran-2-ylmethyl)aniline (AFG-90MH), were used in this study. The resulting resin systems were designated as AFG-90MH-MDA, AFG-90MH-MOEA, AFG-90MH-MOCA, and AFG-90MH-MCDEA. After curing, these systems were named AFG-90MH-MDA-C, AFG-90MH-MOEA-C, AFG-90MH-MOCA-C, and AFG-90MH-MCDEA-C. The influence of the structure of the diamines on the processability, curing reaction activity, and thermal and mechanical properties (including flexural and tensile properties) of the epoxy resins were investigated. These systems demonstrate excellent processability with wide processing windows ranging from 30 °C to 110–160 °C while maintaining low viscosity. Consistent apparent activation energy (Ea) trends via both Kissinger and Flynn-Wall-Ozawa methods were observed. The epoxy systems exhibit the following increasing Ea sequence: AFG-90MH-MDA < AFG-90MH-MOEA < AFG-90MH-MOCA < AFG-90MH-MCDEA. The processability and curing reaction kinetic results indicate that the reactivities of the diamines decrease in the order: MDA > MOEA > MOCA > MCDEA. Polar chlorine substituents in diamines strengthen intermolecular interactions, thereby enhancing mechanical performance. The flexural strength of cured epoxy systems decreases as follows with corresponding values: AFG-90MH-MOCA-C (165 MPa) > AFG-90MH-MDA-C (158 MPa) > AFG-90MH-MCDEA-C (148 MPa) > AFG-90MH-MOEA-C (136 MPa). Diamines with substituents like chlorine or ethyl groups reduce the glass transition temperatures (Tg) of the cured resin systems. However, the cured resin systems with the diamines containing chlorine demonstrate superior thermal performance compared to those with ethyl groups. The cured epoxy systems exhibit the following descending glass transition temperature order with corresponding values: AFG-90MH-MDA-C (213 °C) > AFG-90MH-MOCA-C (190 °C) > AFG-90MH-MCDEA-C (183 °C) > AFG-90MH-MOEA-C (172 °C). Full article
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14 pages, 895 KiB  
Article
Form and Temporal Integration in the Perception of Simple Glass Patterns
by Rita Donato, Michele Vicovaro, Massimo Nucci, Marco Roccato, Gianluca Campana and Andrea Pavan
Vision 2025, 9(3), 69; https://doi.org/10.3390/vision9030069 - 4 Aug 2025
Abstract
This study presents a reanalysis of existing data to clarify how the visual system processes simple dynamic Glass patterns (GPs), with a particular focus on translational configurations. By combining datasets from previous studies, we apply a mixed-effects modeling approach—which offers advantages over the [...] Read more.
This study presents a reanalysis of existing data to clarify how the visual system processes simple dynamic Glass patterns (GPs), with a particular focus on translational configurations. By combining datasets from previous studies, we apply a mixed-effects modeling approach—which offers advantages over the statistical methods used in previous studies—to investigate the contributions of pattern update rate and number of unique frames to perceptual sensitivity. Our findings indicate that the number of unique frames is the most robust predictor of discrimination thresholds, supporting the idea that the visual system integrates global form information across multiple frames—a process consistent with spatiotemporal summation. In contrast, the pattern update rate showed a weaker, though statistically significant, effect. This suggests that faster updates help preserve temporal consistency between frames, facilitating global form extraction. These results align with previous observations on complex dynamic GPs, where discrimination thresholds decrease with more unique frames, suggesting that the summation of form signals across time plays a key role in form–motion perception. By adopting a mixed-effects modeling approach, our reanalysis provides new insights into the mechanisms underlying global form perception in dynamic GPs. Full article
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17 pages, 6882 KiB  
Article
Development and Evaluation of a Solar Milk Pasteurizer for the Savanna Ecological Zones of West Africa
by Iddrisu Ibrahim, Paul Tengey, Kelci Mikayla Lawrence, Joseph Atia Ayariga, Fortune Akabanda, Grace Yawa Aduve, Junhuan Xu, Robertson K. Boakai, Olufemi S. Ajayi and James Owusu-Kwarteng
Solar 2025, 5(3), 38; https://doi.org/10.3390/solar5030038 - 4 Aug 2025
Abstract
In many developing African countries, milk safety is often managed through traditional methods such as fermentation or boiling over firewood. While these approaches reduce some microbial risks, they present critical limitations. Firewood dependency contributes to deforestation, depletion of agricultural residues, and loss of [...] Read more.
In many developing African countries, milk safety is often managed through traditional methods such as fermentation or boiling over firewood. While these approaches reduce some microbial risks, they present critical limitations. Firewood dependency contributes to deforestation, depletion of agricultural residues, and loss of soil fertility, which, in turn, compromise environmental health and food security. Solar pasteurization provides a reliable and sustainable method for thermally inactivating pathogenic microorganisms in milk and other perishable foods at sub-boiling temperatures, preserving its nutritional quality. This study aimed to evaluate the thermal and microbial performance of a low-cost solar milk pasteurization system, hypothesized to effectively reduce microbial contaminants and retain milk quality under natural sunlight. The system was constructed using locally available materials and tailored to the climatic conditions of the Savanna ecological zone in West Africa. A flat-plate glass solar collector was integrated with a 0.15 cm thick stainless steel cylindrical milk vat, featuring a 2.2 cm hot water jacket and 0.5 cm thick aluminum foil insulation. The system was tested in Navrongo, Ghana, under ambient temperatures ranging from 30 °C to 43 °C. The pasteurizer successfully processed up to 8 L of milk per batch, achieving a maximum milk temperature of 74 °C by 14:00 GMT. Microbial analysis revealed a significant reduction in bacterial load, from 6.6 × 106 CFU/mL to 1.0 × 102 CFU/mL, with complete elimination of coliforms. These results confirmed the device’s effectiveness in achieving safe pasteurization levels. The findings demonstrate that this locally built solar pasteurization system is a viable and cost-effective solution for improving milk safety in arid, electricity-limited regions. Its potential scalability also opens avenues for rural entrepreneurship in solar-powered food and water treatment technologies. Full article
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22 pages, 11423 KiB  
Article
Adornments from the Sea: Fish Skins, Heads, Bones, Vertebras, and Otoliths Used by Alaska Natives and Greenlandic Inuit
by Elisa Palomino
Wild 2025, 2(3), 30; https://doi.org/10.3390/wild2030030 - 4 Aug 2025
Viewed by 20
Abstract
This paper investigates the cultural, spiritual, and ecological use and value of fish by-products in the material practices of Alaska Native (Indigenous Peoples are the descendants of the populations who inhabited a geographical region at the time of colonisation and who retain some [...] Read more.
This paper investigates the cultural, spiritual, and ecological use and value of fish by-products in the material practices of Alaska Native (Indigenous Peoples are the descendants of the populations who inhabited a geographical region at the time of colonisation and who retain some or all of their own social, economic, cultural, and political institutions. In this paper, I use the terms “Indigenous” and “Native” interchangeably. In some countries, one of these terms may be favoured over the other.) and Greenlandic Inuit women. It aims to uncover how fish remnants—skins, bones, bladders, vertebrae, and otoliths—were transformed through tanning, dyeing, and sewing into garments, containers, tools, oils, glues, and adornments, reflecting sustainable systems of knowledge production rooted in Arctic Indigenous lifeways. Drawing on interdisciplinary methods combining Indigenist research, ethnographic records, and sustainability studies, the research contextualises these practices within broader environmental, spiritual, and social frameworks. The findings demonstrate that fish-based technologies were not merely utilitarian but also carried symbolic meanings, linking wearers to ancestral spirits, animal kin, and the marine environment. These traditions persisted even after European contact and the introduction of glass trade beads, reflecting continuity and cultural adaptability. The paper contributes to academic discourse on Indigenous innovation and environmental humanities by offering a culturally grounded model of zero-waste practice and reciprocal ecology. It argues that such ancestral technologies are directly relevant to contemporary sustainability debates in fashion and material design. By documenting these underexamined histories, the study provides valuable insight into Indigenous resilience and offers a critical framework for integrating Indigenous knowledge systems into current sustainability practices. Full article
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12 pages, 1806 KiB  
Article
Massive Fluctuations in the Derivatives of Pair Distribution Function Minima and Maxima During the Glass Transition
by Michael I. Ojovan, Anh Khoa Augustin Lu and Dmitri V. Louzguine-Luzgin
Metals 2025, 15(8), 869; https://doi.org/10.3390/met15080869 (registering DOI) - 2 Aug 2025
Viewed by 178
Abstract
Parametric changes in the first coordination shell (FCS) of a vitreous metallic Pd42.5Cu30Ni7.5P20 alloy are analysed, aiming to confirm the identification of the glass transition temperature (Tg) via processing of XRD patterns utilising [...] Read more.
Parametric changes in the first coordination shell (FCS) of a vitreous metallic Pd42.5Cu30Ni7.5P20 alloy are analysed, aiming to confirm the identification of the glass transition temperature (Tg) via processing of XRD patterns utilising radial and pair distribution functions (RDFs and PDFs) and their evolution with temperature. The Wendt–Abraham empirical criterion of glass transition and its modifications are confirmed in line with previous works, which utilised the kink of the temperature dependences of the minima and maxima of both the PDF and the maxima of the structure factor S(q). Massive fluctuations are, however, identified near the Tg of the derivatives of the minima and maxima of the PDF and maxima of S(q), which adds value to understanding the glass transition in the system as a true second-order-like phase transformation in the non-equilibrium system of atoms. Full article
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20 pages, 2735 KiB  
Article
Techno-Economic Assessment of Electrification and Hydrogen Pathways for Optimal Solar Integration in the Glass Industry
by Lorenzo Miserocchi and Alessandro Franco
Solar 2025, 5(3), 35; https://doi.org/10.3390/solar5030035 - 1 Aug 2025
Viewed by 95
Abstract
Direct electrification and hydrogen utilization represent two key pathways for decarbonizing the glass industry, with their effectiveness subject to adequate furnace design and renewable energy availability. This study presents a techno-economic assessment for optimal solar energy integration in a representative 300 t/d oxyfuel [...] Read more.
Direct electrification and hydrogen utilization represent two key pathways for decarbonizing the glass industry, with their effectiveness subject to adequate furnace design and renewable energy availability. This study presents a techno-economic assessment for optimal solar energy integration in a representative 300 t/d oxyfuel container glass furnace with a specific energy consumption of 4.35 GJ/t. A mixed-integer linear programming formulation is developed to evaluate specific melting costs, carbon emissions, and renewable energy self-consumption and self-production rates across three scenarios: direct solar coupling, battery storage, and a hydrogen-based infrastructure. Battery storage achieves the greatest reductions in specific melting costs and emissions, whereas hydrogen integration minimizes electricity export to the grid. By incorporating capital investment considerations, the study quantifies the cost premiums and capacity requirements under varying decarbonization targets. A combination of 30 MW of solar plant and 9 MW of electric boosting enables the realization of around 30% carbon reduction while increasing total costs by 25%. Deeper decarbonization targets require more advanced systems, with batteries emerging as a cost-effective solution. These findings offer critical insights into the economic and environmental trade-offs, as well as the technical constraints associated with renewable energy adoption in the glass industry, providing a foundation for strategic energy and decarbonization planning. Full article
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11 pages, 3403 KiB  
Article
Optical Design and Lens Fabrication for Automotive Thermal Imaging Using Chalcogenide Glass
by Young-Soo Choi and Ji-Kwan Kim
Micromachines 2025, 16(8), 901; https://doi.org/10.3390/mi16080901 (registering DOI) - 31 Jul 2025
Viewed by 150
Abstract
This paper is about the design and fabrication of infrared lenses, which are the core components of thermal imaging cameras to be mounted on vehicles. To produce an athermalized optical system, chalcogenide glass (As40Se60) with a lower thermo-optic coefficient [...] Read more.
This paper is about the design and fabrication of infrared lenses, which are the core components of thermal imaging cameras to be mounted on vehicles. To produce an athermalized optical system, chalcogenide glass (As40Se60) with a lower thermo-optic coefficient (dn/dT) than germanium was adopted as a lens material, and each lens was designed so that defocus occurs in opposite directions depending on temperature. The designed lens was fabricated using a compression molding method, and the molded lenses showed less than 1.5 μm of form error (PV) using a mold iteration process. Through evaluations of MTF and thermal images obtained from the lens module, it was judged that this optical design process is obtainable. Full article
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26 pages, 3459 KiB  
Article
Compressive Behaviour of Sustainable Concrete-Filled Steel Tubes Using Waste Glass and Rubber Glove Fibres
by Zobaer Saleheen, Tatheer Zahra, Renga Rao Krishnamoorthy and Sabrina Fawzia
Buildings 2025, 15(15), 2708; https://doi.org/10.3390/buildings15152708 - 31 Jul 2025
Viewed by 119
Abstract
To reduce the carbon footprint of the concrete industry and promote a circular economy, this study explores the reuse of waste materials such as glass powder (GP) and nitrile rubber (NR) fibres in concrete. However, the inclusion of these waste materials results in [...] Read more.
To reduce the carbon footprint of the concrete industry and promote a circular economy, this study explores the reuse of waste materials such as glass powder (GP) and nitrile rubber (NR) fibres in concrete. However, the inclusion of these waste materials results in lower compressive strength compared to conventional concrete, limiting their application to non-structural elements. To overcome this limitation, this study adopts the concept of confined concrete by developing concrete-filled steel tube (CFST) stub columns. In total, twelve concrete mix variations were developed, with and without steel tube confinement. GP was utilised at replacement levels of 10–30% by weight of cement, while NR fibres were introduced at 0.5% and 1% by volume of concrete. The findings demonstrate that the incorporation of GP and NR fibres leads to a reduction in compressive strength, with a compounded effect observed when both materials are combined. Steel confinement within CFST columns effectively mitigated the strength reductions, restoring up to 17% of the lost capacity and significantly improving ductility and energy absorption capacity. All CFST columns exhibited consistent local outward buckling failure mode, irrespective of the concrete mix variations. A comparison with predictions from existing design codes and empirical models revealed discrepancies, underscoring the need for refined design approaches for CFST columns incorporating sustainable concrete infill. This study contributes valuable insights into the development of eco-friendly, high-performance structural systems, highlighting the potential of CFST technology in facilitating the adoption of waste materials in the construction sector. Full article
(This article belongs to the Section Building Materials, and Repair & Renovation)
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25 pages, 7101 KiB  
Article
Study on the Influence of Ultrafast Laser Welding Parameters on Glass Bonding Performance
by Aowei Xing, Ziwei Li, Tianfeng Zhou, Zhiyuan Huang, Weijia Guo and Peng Liu
Micromachines 2025, 16(8), 888; https://doi.org/10.3390/mi16080888 - 30 Jul 2025
Viewed by 244
Abstract
Glass enjoys a wide range of applications thanks to its superior optical properties and chemical stability. Conventional glass bonding techniques suffer from low efficiency, limited precision, and high cost. Moreover, for multilayer glass bonding, repeated alignment is often required, further complicating the process. [...] Read more.
Glass enjoys a wide range of applications thanks to its superior optical properties and chemical stability. Conventional glass bonding techniques suffer from low efficiency, limited precision, and high cost. Moreover, for multilayer glass bonding, repeated alignment is often required, further complicating the process. These limitations have become major constraints on the advancement of microfluidic chip technologies. Laser bonding of microfluidic chips offers high precision and efficiency. This research first uses an ultrafast laser system to investigate how processing parameters affect weld morphology, identifying the optimal parameter range. Then, this paper proposes two methods for ultrafast-laser bonding of multilayer glass with different thicknesses and performs preliminary experiments to demonstrate their feasibility. The research in this paper could expand the fabrication method of microfluidic chips and lay a foundation for the wider application of microfluidic chips. Full article
(This article belongs to the Special Issue Ultra-Precision Micro Cutting and Micro Polishing)
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39 pages, 9517 KiB  
Article
Multidimensional Evaluation Framework and Classification Strategy for Low-Carbon Technologies in Office Buildings
by Hongjiang Liu, Yuan Song, Yawei Du, Tao Feng and Zhihou Yang
Buildings 2025, 15(15), 2689; https://doi.org/10.3390/buildings15152689 - 30 Jul 2025
Viewed by 147
Abstract
The global climate crisis has driven unprecedented agreements among nations on carbon mitigation. With China’s commitment to carbon peaking and carbon neutrality targets, the building sector has emerged as a critical focus for emission reduction, particularly because office buildings account for over 30% [...] Read more.
The global climate crisis has driven unprecedented agreements among nations on carbon mitigation. With China’s commitment to carbon peaking and carbon neutrality targets, the building sector has emerged as a critical focus for emission reduction, particularly because office buildings account for over 30% of building energy consumption. However, a systematic and regionally adaptive low-carbon technology evaluation framework is lacking. To address this gap, this study develops a multidimensional decision-making system to quantify and rank low-carbon technologies for office buildings in Beijing. The method includes four core components: (1) establishing three archetypal models—low-rise (H ≤ 24 m), mid-rise (24 m < H ≤ 50 m), and high-rise (50 m < H ≤ 100 m) office buildings—based on 99 office buildings in Beijing; (2) classifying 19 key technologies into three clusters—Envelope Structure Optimization, Equipment Efficiency Enhancement, and Renewable Energy Utilization—using bibliometric analysis and policy norm screening; (3) developing a four-dimensional evaluation framework encompassing Carbon Reduction Degree (CRD), Economic Viability Degree (EVD), Technical Applicability Degree (TAD), and Carbon Intensity Degree (CID); and (4) conducting a comprehensive quantitative evaluation using the AHP-entropy-TOPSIS algorithm. The results indicate distinct priority patterns across the building types: low-rise buildings prioritize roof-mounted photovoltaic (PV) systems, LED lighting, and thermal-break aluminum frames with low-E double-glazed laminated glass. Mid- and high-rise buildings emphasize integrated PV-LED-T8 lighting solutions and optimized building envelope structures. Ranking analysis further highlights LED lighting, T8 high-efficiency fluorescent lamps, and rooftop PV systems as the top-recommended technologies for Beijing. Additionally, four policy recommendations are proposed to facilitate the large-scale implementation of the program. This study presents a holistic technical integration strategy that simultaneously enhances the technological performance, economic viability, and carbon reduction outcomes of architectural design and renovation. It also establishes a replicable decision-support framework for decarbonizing office and public buildings in cities, thereby supporting China’s “dual carbon” goals and contributing to global carbon mitigation efforts in the building sector. Full article
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19 pages, 3242 KiB  
Article
Augmented Reality Navigation for Acupuncture Procedures with Smart Glasses
by Shin-Yan Chiou, Hsiao-Hsiang Chang, Yu-Cheng Chen and Geng-Hao Liu
Electronics 2025, 14(15), 3025; https://doi.org/10.3390/electronics14153025 - 29 Jul 2025
Viewed by 178
Abstract
Traditional acupuncture relies on the precise selection of acupuncture points to adjust Qi flow along meridians. Traditionally, acupuncture points are localized using cun (or body-relative cun) as a proportional measurement. However, locating specific points can be challenging, even for experienced practitioners. This study [...] Read more.
Traditional acupuncture relies on the precise selection of acupuncture points to adjust Qi flow along meridians. Traditionally, acupuncture points are localized using cun (or body-relative cun) as a proportional measurement. However, locating specific points can be challenging, even for experienced practitioners. This study aims to enhance the accuracy and efficiency of acupuncture point localization by introducing an augmented reality (AR) navigation system utilizing AR glasses (Magic Leap One). The system employs a Six-Point Landmark-Based AR Registration method to overlay an acupuncture point model onto a patient’s head without the need for external markers. Methods included testing with traditional Chinese medicine students, measuring positional errors, and evaluating stability. Results demonstrated an average error of 5.01 ± 2.64 mm, which is well within the therapeutic range of 2 cun (about 5 cm), with minimal drift during stability tests. This AR system provides an accurate and intuitive tool for practitioners and learners, reducing variability in acupuncture point selection and offering promise for broader clinical applications. Full article
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22 pages, 3056 KiB  
Article
Recycled Glass and Plastic Waste in Sustainable Geopolymer Systems for Affordable Housing Solutions
by Zhao Qing Tang, Yat Choy Wong, Yali Li and Eryadi Kordi Masli
Recycling 2025, 10(4), 147; https://doi.org/10.3390/recycling10040147 - 27 Jul 2025
Viewed by 356
Abstract
The increasing demand for sustainable construction materials has driven research into low-carbon geopolymers that mitigate both cement-related emissions and plastic and glass waste accumulation. This study explores the development of geopolymer concrete incorporating fly ash (FA), slag (S), and FA + S blends, [...] Read more.
The increasing demand for sustainable construction materials has driven research into low-carbon geopolymers that mitigate both cement-related emissions and plastic and glass waste accumulation. This study explores the development of geopolymer concrete incorporating fly ash (FA), slag (S), and FA + S blends, with 10% recycled crushed glass (RCG) and recycled plastic waste (RPW) as partial coarse aggregate replacements. Compressive strength testing revealed that FA + S-based geopolymers (25FA + S) with 100% ordinary Portland cement (OPC) replacement achieved a 7-day strength of 24.6 MPa, representing a 98% improvement over control specimens. Slag-based geopolymers demonstrated water absorption properties comparable to OPC, indicating enhanced durability. Microstructural analyses using SEM, XRD, and EDS confirmed the formation of a dense aluminosilicate matrix, with slag promoting FA reactivity and reinforcing interfacial transition zone (ITZ). These effects contributed to superior mechanical performance and water resistance. Despite minor shrinkage-induced cracking, full OPC replacement with S or FA + S geopolymers outperformed control specimens, consistently exceeding the target strength of 15 MPa required for low-impact, single-story housing applications within seven days. These findings underscore the potential of geopolymer systems for rapid and sustainable construction, offering an effective solution for reducing carbon footprints and repurposing industrial waste. Full article
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23 pages, 954 KiB  
Review
The Role of Cobalt Ions in Angiogenesis—A Review
by Wiktor Gregorowicz and Lukasz Pajchel
Int. J. Mol. Sci. 2025, 26(15), 7236; https://doi.org/10.3390/ijms26157236 - 26 Jul 2025
Viewed by 374
Abstract
Cobalt is an essential trace element involved in key biological processes. It serves most notably as a component of vitamin B12 (cobalamin) and a regulator of erythropoiesis. While cobalt deficiency can lead to disorders such as megaloblastic anemia, excess cobalt poses toxicological [...] Read more.
Cobalt is an essential trace element involved in key biological processes. It serves most notably as a component of vitamin B12 (cobalamin) and a regulator of erythropoiesis. While cobalt deficiency can lead to disorders such as megaloblastic anemia, excess cobalt poses toxicological risks to the thyroid, cardiovascular, and hematopoietic systems. In recent years, cobalt ions (Co2+) have gained attention for their ability to mimic hypoxia and promote angiogenesis. This represents a crucial mechanism for tissue regeneration. Cobalt mediates this effect mainly by stabilizing hypoxia-inducible factor 1α (HIF-1α) under normoxic conditions, thereby upregulating angiogenic genes, including VEGF, FGF, and EPO. Experimental studies—from cell culture to animal models—have demonstrated cobalt-induced enhancement of endothelial proliferation, migration, and microvascular formation. Emerging evidence also indicates that Co2+-stimulated macrophages secrete integrin-β1-rich exosomes. These exosomes enhance endothelial motility and tubulogenesis independently of VEGF. Furthermore, cobalt-modified biomaterials have been developed to deliver cobalt ions in a controlled manner. Examples include cobalt-doped β-tricalcium phosphate or bioactive glasses. These materials support both angiogenesis and osteogenesis.This review summarizes current findings on cobalt’s role in angiogenesis. The emphasis is on its potential in cobalt-based biomaterials for tissue engineering and regenerative medicine. Full article
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12 pages, 6639 KiB  
Article
Study of Space Micro Solid Thruster Using 3D-Printed Short Glass Fiber Reinforced Polyamide
by Haibo Yang, Zhongcan Chen, Xudong Yang, Chang Xu and Hanyu Deng
Aerospace 2025, 12(8), 663; https://doi.org/10.3390/aerospace12080663 - 26 Jul 2025
Viewed by 226
Abstract
To meet the rapid maneuverability and lightweight demands of micro-nano satellites, a space micro solid thruster using 3D-printed short glass fiber reinforced polyamide 6 (PA6GF) composites was developed. Thruster shells with wall thicknesses of 4, 3, and 2.5 mm were designed, and ground [...] Read more.
To meet the rapid maneuverability and lightweight demands of micro-nano satellites, a space micro solid thruster using 3D-printed short glass fiber reinforced polyamide 6 (PA6GF) composites was developed. Thruster shells with wall thicknesses of 4, 3, and 2.5 mm were designed, and ground ignition tests were conducted to monitor chamber pressure and shell temperature. Compared with conventional metallic thrusters, PA6GF composites have exhibited excellent thermal insulation and sufficient mechanical strength. Under 8 MPa and 2773 K ignition conditions, the shell thickness was reduced to 2.5 mm and could withstand pressures up to 10.37 MPa. These results indicate that PA6GF composites are well-suited for space micro solid thrusters with inner diameters of 15–70 mm, offering new possibilities for lightweight space propulsion system design. Full article
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