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21 pages, 3962 KB  
Article
Improving Thermal Performance of Solar Heating Systems
by Sebastian Pater and Krzysztof Kupiec
Appl. Sci. 2025, 15(20), 11118; https://doi.org/10.3390/app152011118 - 16 Oct 2025
Abstract
The solar energy reaching the immediate surroundings of a single-family house throughout the year is sufficient to repeatedly and fully cover its heating needs during the heating season in a temperate climate. Nevertheless, modern technology is not yet able to fully solve the [...] Read more.
The solar energy reaching the immediate surroundings of a single-family house throughout the year is sufficient to repeatedly and fully cover its heating needs during the heating season in a temperate climate. Nevertheless, modern technology is not yet able to fully solve the problem of thermal self-sufficiency in single-family houses. It is therefore advisable to seek solutions that improve the thermal efficiency of domestic solar installations. Efficient use of solar radiation heat accumulated during the summer months for heating requires the use of high-volume storage tanks. Another option is to discharge excess heat outside the system during the summer. This publication focuses on the latter solution. A model of the solar heating system for a residential building and pool with a storage tank powered by solar energy has been developed. Simulation calculations were performed, showing that the removal of excess heat is a beneficial solution, especially when this energy can be used to heat water in the pool. The calculations concerned the heating of a single-family house in a temperate climate. Lowering the temperature of the water in the storage tank reduces heat losses from the tank to the environment (ground), while supplying the solar collectors with lower-temperature fluid increases the driving force of the heat transfer process. Full article
(This article belongs to the Section Applied Thermal Engineering)
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17 pages, 1955 KB  
Article
Structural Analysis of Oil-Spill Boom Grounding at Low Tide
by Frédéric Muttin
J. Mar. Sci. Eng. 2025, 13(10), 1984; https://doi.org/10.3390/jmse13101984 - 16 Oct 2025
Abstract
Oil-spill booms in shallow waters and high tidal amplitudes could ground on the seabed and retain high amounts of seawater. The object of this study is to estimate the mooring force at both boom section ends and the occurrence of submarining observed along [...] Read more.
Oil-spill booms in shallow waters and high tidal amplitudes could ground on the seabed and retain high amounts of seawater. The object of this study is to estimate the mooring force at both boom section ends and the occurrence of submarining observed along the crest line. We use a Lagrangian linear elastic membrane theory incorporating the non-linear Green strain tensor and a non-updated hydrostatic or hydrodynamic load. We describe a numerical method using geometrically non-linear finite elements and 2D vertical hydrostatic pressure estimation. The calculated results indicate the role of hydrostatic pressure caused by the water height difference—several centimeters at the mid-section—and the influence of the elasticity module. We consolidate the mooring force results by supposing 2D horizontal hydrodynamic pressure. We associate the current velocity that produces the same mooring force with that generated by the hydrostatic load. The associated Froude number is close to 0.8. Full article
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25 pages, 2897 KB  
Article
Rational Approach for Evaluating Fire Resistance of Prestressed Concrete Beams Strengthened with Fiber-Reinforced Polymers
by Venkatesh Kodur, Tejeswar Rayala and Hee Sun Kim
Polymers 2025, 17(20), 2773; https://doi.org/10.3390/polym17202773 - 16 Oct 2025
Abstract
A rational approach is proposed for evaluating the fire resistance of fiber-reinforced polymers (FRP)-strengthened prestressed concrete (PC) beams. This approach expands on conventional fire design principles for PC beams, while incorporating the effects of FRP reinforcement and fire insulation into strength calculations under [...] Read more.
A rational approach is proposed for evaluating the fire resistance of fiber-reinforced polymers (FRP)-strengthened prestressed concrete (PC) beams. This approach expands on conventional fire design principles for PC beams, while incorporating the effects of FRP reinforcement and fire insulation into strength calculations under fire exposure. Simplified equations are utilized to evaluate the cross-sectional temperature distribution in fire-exposed FRP-strengthened PC beams, considering both insulated and uninsulated scenarios. These cross-sectional temperature profiles are then utilized to evaluate the reductions in the strengths of concrete, steel, and FRP based on their temperature-dependent mechanical properties. The moment capacity of the FRP-strengthened PC beams is determined at various fire exposure durations by applying force equilibrium and strain compatibility principles, assuming a full bond with no relative slip between the FRP and the concrete interface under fire exposure. The critical strength limit state is applied at each time interval to determine the failure state of the FRP-strengthened PC beam, with the final time to failure considered to be the fire resistance of the beam. The proposed approach is validated by comparing its results with available test data from FRP-strengthened reinforced concrete (RC) beams. The validated model is applied to evaluate critical parameters governing the fire resistance of FRP-strengthened PC beam. The results show that, without fire insulation, FRP-strengthened PC beams undergo a significant reduction in moment capacity early into fire exposure and fail within 75 min due to the rapid strength degradation of both the CFRP and the prestressing steel. In contrast, the application of 25 mm thick fire insulation allows these beams to retain a substantial portion of their load-bearing capacity for up to 3 h of fire exposure. Full article
(This article belongs to the Section Polymer Composites and Nanocomposites)
21 pages, 3567 KB  
Article
Molecular Modelling of the Adsorption and Delivery of α-Pinene and Similar Terpenes of Essential Oils on Montmorillonite Surfaces
by Shamsa Kanwal, Alfonso Hernández-Laguna and C. Ignacio Sainz-Díaz
Nanomaterials 2025, 15(20), 1573; https://doi.org/10.3390/nano15201573 - 16 Oct 2025
Abstract
Alkylic molecules are found as some of the main components of natural essential oils. These essential oils offer several therapeutic properties in skin treatments and cosmetics. Systems providing controlled release of these molecules through the skin tissue are a challenge for their applications. [...] Read more.
Alkylic molecules are found as some of the main components of natural essential oils. These essential oils offer several therapeutic properties in skin treatments and cosmetics. Systems providing controlled release of these molecules through the skin tissue are a challenge for their applications. This work explores some properties of the crystal structure of α-pinene and the adsorption and desorption of five terpenoid components of essential oils, such as α-pinene, limonene, β-ocimene, β-caryophyllene, and β-elemene, in the confined surfaces provided by natural clay minerals, particularly montmorillonite (MNT). These terpenoids have a methyl-ethenyl group as their common structural feature. Molecular modelling calculations have been applied at the atomic scale, including force fields, quantum mechanical methods, and molecular dynamics simulations. We calculated the crystallographic and spectroscopic properties of the α-pinene crystal via density functional theory (DFT)-level calculations, which were very close to the known experimental data. Moreover, this work explored the adsorption and desorption of these molecules in confined surfaces provided by MNT. Molecular dynamics simulations also showed the adsorption of these organics in the confined interlayer space of MNT at room temperature and allowed us to know the diffusion coefficient of these adsorbates in this material. The direct adsorption process of these molecules in the vapour phase is not energetically favourable, suggesting the use of non-aqueous solvents and kinetics and thermodynamic conditions for this process. However, the release of these molecules into aqueous media are energetically favourable, predicting that MNT–essential oil can be an excellent pharmaceutical formulation to be delivered in skin as a bioactive preparation with anti-inflammatory or cosmetic power. This research was performed to predict possible therapeutic applications for future experimental works. Full article
(This article belongs to the Special Issue Advanced Nanomedicine for Drug Delivery)
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13 pages, 3142 KB  
Article
Three-Dimensional Photogrammetric Assessment of Facial Symmetry Improvement Following Botulinum Toxin Treatment in Patients with Facial Palsy: An Observational Study
by Robin Pradel, Barbara Lerhe, Philippe Kestemont, Charlotte Helmer, Charles Savoldelli and Olina Rios
J. Clin. Med. 2025, 14(20), 7298; https://doi.org/10.3390/jcm14207298 (registering DOI) - 16 Oct 2025
Abstract
Background/Objectives: Facial palsy causes both functional and aesthetic impairments, with asymmetry significantly affecting quality of life. Botulinum toxin injections are increasingly used to restore facial balance by reducing contralateral hyperactivity, but outcome assessments remain largely subjective. The objective of this study was [...] Read more.
Background/Objectives: Facial palsy causes both functional and aesthetic impairments, with asymmetry significantly affecting quality of life. Botulinum toxin injections are increasingly used to restore facial balance by reducing contralateral hyperactivity, but outcome assessments remain largely subjective. The objective of this study was to evaluate the ability of three-dimensional (3D) stereophotogrammetry coupled with root mean square (RMS) surface analysis to objectively quantify improvements in facial symmetry following botulinum toxin treatment and to support clinicians in patient care. Methods: Sixteen adults with long-standing unilateral peripheral facial palsy underwent individualized botulinum toxin injections. Three-dimensional images were acquired using the Vectra H2 system before and 2–3 weeks after injection at peak efficacy. Five facial expressions (neutral, surprise, frown, Mona Lisa smile, and forced smile) were analyzed. RMS values were calculated for the whole face and facial thirds. Clinical assessment included House–Brackmann and Sunnybrook scores. Results: Whole-face RMS values decreased significantly after injection (1.51 ± 0.42 vs. 1.35 ± 0.43, p < 0.001). Improvements were observed across all thirds, most notably in the middle third. During expression, symmetry improved for all movements, with the strongest effects for surprise (d = 1.270), Mona Lisa smile (d = 0.870), and frown (d = 0.832). Conclusions: Three-dimensional stereophotogrammetry with RMS analysis provides an objective and reproducible method to quantify changes in facial symmetry after botulinum toxin treatment. This technique may complement clinical scoring systems and support personalized treatment planning in facial palsy patients. Full article
(This article belongs to the Special Issue Recent Advances in Facial Palsy Management)
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19 pages, 419 KB  
Article
Information-Theoretic Analysis of Selected Water Force Fields: From Molecular Clusters to Bulk Properties
by Rodolfo O. Esquivel, Hazel Vázquez-Hernández and Alexander Pérez de La Luz
Entropy 2025, 27(10), 1073; https://doi.org/10.3390/e27101073 - 15 Oct 2025
Abstract
We present a comprehensive information-theoretic evaluation of three widely used rigid water models (TIP3P, SPC, and SPC/ε) through systematic analysis of water clusters ranging from single molecules to 11-molecule aggregates. Five fundamental descriptors—Shannon entropy, Fisher information, disequilibrium, LMC complexity, and Fisher–Shannon [...] Read more.
We present a comprehensive information-theoretic evaluation of three widely used rigid water models (TIP3P, SPC, and SPC/ε) through systematic analysis of water clusters ranging from single molecules to 11-molecule aggregates. Five fundamental descriptors—Shannon entropy, Fisher information, disequilibrium, LMC complexity, and Fisher–Shannon complexity—were calculated in both position and momentum spaces to quantify electronic delocalizability, localization, uniformity, and structural sophistication. Clusters containing 1, 3, 5, 7, 9, and 11 molecules (denoted 1 M, 3 M, 5 M, 7 M, 9 M, and 11 M) were selected to balance computational tractability with representative scaling behavior. Molecular dynamics simulations validated the force fields against experimental bulk properties (density, dielectric constant, self-diffusion coefficient), while statistical analysis using Shapiro–Wilk normality tests and Student’s t-tests ensured robust discrimination between models. Our results reveal distinct scaling behaviors that correlate with experimental accuracy: SPC/ε demonstrates superior electronic structure representation with optimal entropy–information balance and enhanced complexity measures, while TIP3P shows excessive localization and reduced complexity that worsen with increasing cluster size. The transferability from clusters to bulk properties is established through systematic convergence of information-theoretic measures toward bulk-like behavior. The methodology establishes information-theoretic analysis as a useful tool for comprehensive force field evaluation. Full article
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13 pages, 3231 KB  
Article
Sex and Limb Dominance Differences in Postural Control Performance of Young Adults: A Third-Order Polynomial Decay Approach
by Yang Sun, Hanbing Wu, Xingchen Zhang, Jiujiang Liu, Guanying Wang, Lian Duan and Yuan Gao
Symmetry 2025, 17(10), 1734; https://doi.org/10.3390/sym17101734 - 14 Oct 2025
Abstract
This study systematically evaluated postural control performance on dominant and non-dominant sides in young adults of different sexes using a Third-Order Polynomial Decay fitting method combined with time-domain stability features. A total of 126 participants (66 males, 60 females) performed single-leg landing tasks, [...] Read more.
This study systematically evaluated postural control performance on dominant and non-dominant sides in young adults of different sexes using a Third-Order Polynomial Decay fitting method combined with time-domain stability features. A total of 126 participants (66 males, 60 females) performed single-leg landing tasks, during which ground reaction forces (GRF) and center of pressure (COP) data were collected using a Kistler 3D force platform and Bioware acquisition system. Dynamic stability times in the anterior–posterior, medial–lateral, and vertical directions were calculated with polynomial fitting, and additional time-domain measures were used to assess static and dynamic stability. Results showed that on the non-dominant side, participants exhibited significantly longer dynamic stability times (p = 0.015), greater root mean square distance (p = 0.005), and longer total sway path (p = 0.005) in the anterior–posterior direction compared with the dominant side. Significant sex differences were also found in vertical stability index (p = 0.044), dynamic stability index (p = 0.047), total sway path (p < 0.001), anterior–posterior sway path (p = 0.001), and medial–lateral sway path (p < 0.001). In conclusion, the dominant limb demonstrated superior stability, males showed better static control, and females displayed greater dynamic stability, underscoring the importance of targeted non-dominant training and sex-specific balance strategies. Full article
(This article belongs to the Section Life Sciences)
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39 pages, 9645 KB  
Review
Marine-Derived Steroids for Cancer Treatment: Search for Potential Selective Glucocorticoid Receptor Agonists/Modulators (SEGRAMs)
by Ekaterina M. Zhidkova, Ekaterina D. Savina, Ekaterina A. Yurchenko and Ekaterina A. Lesovaya
Mar. Drugs 2025, 23(10), 399; https://doi.org/10.3390/md23100399 (registering DOI) - 14 Oct 2025
Abstract
Steroids, particularly glucocorticoids, are essential components of cancer treatment for both hematological malignancies and solid tumors. The adverse effects of standard steroid-based drugs have forced drug discovery research to develop chemotherapeutics with a more selective mechanism of action and an improved therapeutic index. [...] Read more.
Steroids, particularly glucocorticoids, are essential components of cancer treatment for both hematological malignancies and solid tumors. The adverse effects of standard steroid-based drugs have forced drug discovery research to develop chemotherapeutics with a more selective mechanism of action and an improved therapeutic index. Steroids of natural origin and their analogs are a significant source of novel molecules with a wide spectrum of biological activities. In this review, we aimed to analyze marine-derived steroids and their anti-cancer activity. Moreover, we specifically discussed molecules with not only anti-cancer but also anti-inflammatory activities that could potentially mimic the effects of glucocorticoids. We hypothesized that several of the reviewed compounds could exhibit affinity to the glucocorticoid receptor, and possess the properties of selective glucocorticoid receptor agonists/modulators with increased therapeutic activity and decreased side effects. The review is based on the literature available in the PubMed, Cochrane, and ClinicalTrials.gov databases and covers the period from 1986 to 2025. The keywords used were “steroids”, “cancer”, and “marine-derived steroids”. The second iteration of the literature search included the keywords “selective glucocorticoid receptor agonists”, “marine-derived”, and “cancer”. In silico calculations of several marine-derived compounds were performed to support the hypothesis based on the literature data. Full article
(This article belongs to the Special Issue Marine Natural Products as Anticancer Agents, 5th Edition)
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18 pages, 2662 KB  
Article
NVH Optimization of Motor Based on Distributed Mathematical Model Under PWM Control
by Kai Zhao, Zhihui Jin and Jian Luo
Energies 2025, 18(20), 5395; https://doi.org/10.3390/en18205395 - 13 Oct 2025
Viewed by 170
Abstract
For the combination of finite elements and control circuits, the calculation is complex and time-consuming, making direct optimization impractical. In this paper, a new distributed node and magnetic circuit model is proposed to simulate the spatial and temporal variation of the distributed air-gap [...] Read more.
For the combination of finite elements and control circuits, the calculation is complex and time-consuming, making direct optimization impractical. In this paper, a new distributed node and magnetic circuit model is proposed to simulate the spatial and temporal variation of the distributed air-gap magnetic density with the current and rotor angle and solve the electromagnetic force wave variation. Compared to other distributed flux-linkage models, the proposed model not only considers the radial magnetic path but also connects adjacent magnetic paths tangentially. The inclusion of this tangential path enhances the mutual interaction between magnetic circuits, leading to a more accurate model. Based on the control circuit model, the electromagnetic force wave changes caused by the harmonic currents under various circuits and operating conditions are calculated, the topology is analyzed and optimized to mitigate critical harmonics, the electromagnetic force wave is reduced, and finally, the model accuracy is verified experimentally. While most distributed flux-linkage models are applied to the optimization of motor performance metrics such as the magnetomotive force (MMF), power, and torque, this paper applies the model to the optimization of the magnetic field strength, the harmonic content, and the corresponding noise, vibration, and harshness (NVH), demonstrating a broader range of applications. This method can be coupled with the control circuit to analyze the changes in electromagnetic force waves and quickly optimize them, improving the accuracy and efficiency of research and development. Full article
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23 pages, 1962 KB  
Article
A Home-Based Balance Exercise Training Program with Intermittent Visual Deprivation for Persons with Chronic Incomplete Spinal Cord Injury: A Pilot Study on Feasibility, Acceptability, and Preliminary Outcomes
by Riccardo Bravi, Sara Guarducci, Giulia Panconi, Magdalena Sicher, Lorenzo Mucchi, Giacomo Lucchesi, Gabriele Righi, Giulio Del Popolo and Diego Minciacchi
Sensors 2025, 25(20), 6320; https://doi.org/10.3390/s25206320 - 13 Oct 2025
Viewed by 229
Abstract
Incomplete spinal cord injury (iSCI) results in impaired postural control and walking ability. Visual over-reliance may occur in iSCI individuals to maintain postural control. This can challenge their postural stability in various contexts of daily life activities. The present study assessed the feasibility, [...] Read more.
Incomplete spinal cord injury (iSCI) results in impaired postural control and walking ability. Visual over-reliance may occur in iSCI individuals to maintain postural control. This can challenge their postural stability in various contexts of daily life activities. The present study assessed the feasibility, acceptability, and preliminary outcomes of balance training with intermittent visual deprivation using stroboscopic glasses on postural control and visual reliance during quiet standing in iSCI individuals. Training impact on walking performance was also evaluated. Seven chronic iSCI individuals participated in a 6-week home-based balance training program, three times weekly, using stroboscopic glasses. Postural and walking abilities were assessed pre- and post-training using a bipedal stance test (BST) and 10 m walking test (10 MWT). BST was performed, with open-eyes (OE) and closed-eyes (CE), on a force plate for three 30 s trials. The center of pressure (CoP) variables included were CoP area (A-CoP) and CoP mean velocity (MV-CoP). Romberg ratios (CE/OE) for two CoP variables were calculated. Duration and speed were measured in 10 MWT. Intervention feasibility was assessed using the feasibility and acceptability questionnaire. Data from able-bodied individuals were recorded and used as references of physiological performance. iSCI individuals were significantly less stable and showed visual over-reliance for postural steadiness compared to controls. Also, their walking ability was impaired. All iSCI individuals completed the training (adherence rate: 84%) and rated it highly feasible. A-CoP and MV-CoP significantly reduced after training in CE condition (p = 0.018, respectively) but not in OE condition (p > 0.05). The Romberg ratio of A-CoP was significantly lower (p = 0.018), but the Romberg ratio of MV-CoP was not (p > 0.05). A significant reduction in duration and increase in speed (p = 0.018, respectively) in performing the 10 MWT were observed. Preliminary findings from this explorative study indicated that 6-week home-based balance training with intermittent visual deprivation was feasible, acceptable, and had promising potential benefits in improving postural control with a reduction in visual over-reliance in iSCI individuals. The training enhanced also their walking performance. Full article
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19 pages, 312 KB  
Article
Violence, Inequity, and Their Impact on Health and Access to Healthcare Services Among the Elderly Population of Bogotá
by Carlos Alberto Cano-Gutiérrez, Diego Andrés Chavarro-Carvajal and Julián Andrés Sucerquia-Quintero
Int. J. Environ. Res. Public Health 2025, 22(10), 1555; https://doi.org/10.3390/ijerph22101555 - 13 Oct 2025
Viewed by 203
Abstract
Objective: This study explores the prevalence of violence and forced displacement as indicators of inequity among Bogotá’s elderly population, with a particular focus on how these factors affect their health and access to healthcare services. Methods: This is a subsidiary analysis of the [...] Read more.
Objective: This study explores the prevalence of violence and forced displacement as indicators of inequity among Bogotá’s elderly population, with a particular focus on how these factors affect their health and access to healthcare services. Methods: This is a subsidiary analysis of the SABE-Bogotá survey. The design was a probabilistic cluster sample of 2000 people aged 60 and over. The study was carried out by the Pontificia Universidad Javeriana’s Institute on Aging and cosponsored by Colciencias. The variables of interest were displacement and experiences of violence, assessed through self-reporting. A descriptive analysis of all variables was performed, calculating simple frequency distributions. Subsequently, dependency and association analyses were performed using Chi-square, T-tests, and multivariate logistic regressions, depending on each case. Results: 43.32% of the subjects were victims of some type of violence in the last year, among which offensive language was one of the most frequent. Individuals with severe depression (OR 2.10 [1.21–3.65]) and those who had been victims of displacement (OR 2.55, CI 95% [1.65–3.95]) had the highest risk of violence. The results reveal a direct correlation between these experiences and pre-existing health conditions. For instance, severe depression and a history of displacement were associated with a higher risk of experiencing violence, while the risk of displacement was higher among individuals with diabetes, severe depression, and, crucially, those who lacked access to health insurance. Conclusion: A high percentage of the elderly population in the city of Bogotá has been victims of different types of violence, including ones related to armed conflict and forced displacement, which is a particular and exclusive form of violence suffered by this group of people. These findings suggest that violence and displacement are social determinants of health that exacerbate inequities, underscoring the need for more inclusive health policies and improved access to medical care for this vulnerable population. Full article
26 pages, 3377 KB  
Article
Charge Neutralization During Peptide Transport in the Bacterial SecYEG Translocon
by Laura Nübl, Ekaterina Sobakinskaya and Frank Müh
Biomolecules 2025, 15(10), 1442; https://doi.org/10.3390/biom15101442 - 12 Oct 2025
Viewed by 236
Abstract
The driving force behind protein translocation across the cell membrane is not yet fully understood. In bacteria, there is an electrochemical potential across the cell membrane, which can interact with charged residues in the translocation substrate. In this study, the protonation states of [...] Read more.
The driving force behind protein translocation across the cell membrane is not yet fully understood. In bacteria, there is an electrochemical potential across the cell membrane, which can interact with charged residues in the translocation substrate. In this study, the protonation states of lysine and glutamate, serving as test residues in a peptide translocating across the bacterial channel SecYEG, are investigated by applying Poisson–Boltzmann continuum electrostatic free energy calculations and Monte Carlo titrations to snapshots of molecular dynamics (MD) simulations. A clear shift in protonation probability towards the uncharged state is found for both test residues as they move deeper into the channel. Thus, charge neutralization occurs irrespective of whether the original charge of the test residue is positive (lysine) or negative (glutamate). Electrostatic interactions of acidic and basic residues of SecYEG with the peptide cancel out. The main determinants of the test residue’s protonation state are the dielectric properties of its surroundings and interactions with non-titrating charges in the channel. Crucially, the membrane protein—including its water-filled pore—is assigned a low dielectric constant. The results are discussed in the context of the limitations inherent to continuum electrostatics and MD simulations with fixed protonation states. Full article
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20 pages, 2608 KB  
Article
Analysis of Multi-Stage Slope Displacement and Internal Force of Supporting Structure of Frame Prestressed Anchor Cable Support
by Jingbang Li, Yanpeng Zhu, Shuaihua Ye, Nianxiang Li and Bo Liu
Buildings 2025, 15(20), 3668; https://doi.org/10.3390/buildings15203668 - 11 Oct 2025
Viewed by 246
Abstract
Relying on an engineering case, this study establishes an analysis model using PLAXIS 3D and GeoStudio, and compares and analyzes the slope deformation and internal force of the supporting structure with different slope grades and different platform widths at the same height. The [...] Read more.
Relying on an engineering case, this study establishes an analysis model using PLAXIS 3D and GeoStudio, and compares and analyzes the slope deformation and internal force of the supporting structure with different slope grades and different platform widths at the same height. The results show that the greatest displacement manifests in the lower segments of the slope, which is 12.99 mm, and the maximum anchoring force manifests in the mid-level and lower segments of the slope, which is 288.1 kN. A close correlation is observed between the simulated horizontal displacement of the slope, the maximum axial force of the anchor cable, and the corresponding field measurement results, indicating that the model parameters are satisfactory and that the resulting calculations are reliable. In consideration of the comprehensive stability of the slope, the stability coefficient increased by approximately 1.42% with two-stage slope support and by about 3.48% with four-stage slope support. The axial force of anchor cables was reduced by around 9.5% under two-stage grading, while four-stage grading decreased the maximum axial force of the middle–lower anchors by nearly 27%. The distance between the entrance and exit of the overall sliding surface and the slope surface also decreases with the increase in slope grading and platform width. This study systematically evaluates the combined effects of slope grading, platform width, and frame prestressed anchors. When site conditions permit, slope grading should be prioritized over simply widening the platform, as grading more effectively enhances slope stability and reduces anchor cable loads. Full article
(This article belongs to the Section Building Structures)
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17 pages, 4183 KB  
Article
Behavior of the Vault in Column-Free Large-Span Metro Stations Under Asymmetric Loading
by Jiao-Long Zhang, Guan-Hua Qiao, Zheng Zhou and Cao Li
Appl. Sci. 2025, 15(20), 10944; https://doi.org/10.3390/app152010944 - 11 Oct 2025
Viewed by 217
Abstract
To explore the application of precast concrete construction methods in underground stations, a combined precast and cast in situ construction method was adopted for a long-span column-free underground subway station. To study the stability of large-span underground arch structures under asymmetric loading, a [...] Read more.
To explore the application of precast concrete construction methods in underground stations, a combined precast and cast in situ construction method was adopted for a long-span column-free underground subway station. To study the stability of large-span underground arch structures under asymmetric loading, a full-scale test was conducted using the displacement-force control method. Steel blocks were used to simulate the overlying soil and additional loads on the upper surface of the arch, while the displacement of the arch foot was applied by adjusting the tension of the cables. The maximum tensile stress and maximum compressive stress of the steel bars appeared at the midpoints of the left and right arches, which were less than the yield stress of the steel bars. The results show that the structural stability meets the design requirements and provides a considerable safety margin. A comprehensive analysis of the arch structure under asymmetric loading was carried out through on-site monitoring, numerical simulation, and analytical solutions. The results are in good agreement: compared with the experimental results, the calculated values increase the maximum deflection of the arch by 13.67%, which verifies the reliability of the numerical simulation and analytical solution methods under the same boundary conditions. However, restricted by test conditions, the loading in this study was only applied on one side of the arch crown, which differs from the actual working condition involving full loading first followed by unloading on one side. Full article
(This article belongs to the Special Issue New Challenges in Urban Underground Engineering)
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16 pages, 5856 KB  
Article
Characteristics of Lower Limb Dominant and Nondominant Joint Load Changes After Long-Distance Running in Young Male Runners Under OpenSim Environment
by Xiaocan Li and Lijuan Mao
Sensors 2025, 25(20), 6301; https://doi.org/10.3390/s25206301 - 11 Oct 2025
Viewed by 238
Abstract
This study aims to investigate the characteristics of load changes in the hip, knee, and ankle joints of the dominant and non-dominant lower limbs of young male runners after long-distance running. Using the OpenSim public dataset (containing bilateral biomechanical data before and after [...] Read more.
This study aims to investigate the characteristics of load changes in the hip, knee, and ankle joints of the dominant and non-dominant lower limbs of young male runners after long-distance running. Using the OpenSim public dataset (containing bilateral biomechanical data before and after long-distance running from 20 young male runners), personalized musculoskeletal models were established. Contact forces in three directions at lower limb joints during the running stance phase were calculated. Statistical analysis employed one-dimensional statistical parameter mapping (SPM1d) and two-factor repeated measures ANOVA (time × side). Results revealed significant time × side interaction effects (p < 0.05) for contact forces in the medial–lateral direction at the hip, the anterior–posterior direction at the knee, and all three directions at the ankle. Simple effects analysis showed that post-run medial–lateral hip forces significantly increased during the push-off phase, while anterior–posterior ankle forces significantly increased during the mid-to-late stance phase on both sides (d = 0.718–1.002). For the superior–inferior direction at the hip and knee, only main effects of time or side were present. Post-run joint contact forces significantly increased, with the dominant side consistently exceeding the non-dominant side across multiple stance and push-off phases (d = 0.58–1.6), indicating stable side-to-side differences. These findings indicate that long-distance running not only increases multi-joint loading in the lower limbs but also exacerbates asymmetry between the dominant and non-dominant sides during the initial stance and push-off phases. This redistribution of load, coupled with bilateral control imbalance, may further elevate the risk of injury. Full article
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