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20 pages, 16544 KB  
Article
Investigation on Static Performance of Piers Assembled with Steel Cap Beams and Single Concrete Columns
by Chong Shen, Qingtian Su, Sizhe Wang and Fawas. O. Matanmi
Buildings 2025, 15(19), 3476; https://doi.org/10.3390/buildings15193476 - 26 Sep 2025
Viewed by 281
Abstract
To reduce the weight of prefabricated cap beams, a new type of hybrid pier with a steel cap beam and single concrete column with an innovative flange–rebar–ultra-high-performance concrete (UHPC) connection structure is proposed in this paper. Focusing on the static performance of hybrid [...] Read more.
To reduce the weight of prefabricated cap beams, a new type of hybrid pier with a steel cap beam and single concrete column with an innovative flange–rebar–ultra-high-performance concrete (UHPC) connection structure is proposed in this paper. Focusing on the static performance of hybrid piers, a specimen with a geometric similarity ratio of 1:4 was fabricated for testing. The results showed that the ultimate load-bearing capacity reached 960 kN, and the failure mode was characterized by an obvious overall vertical displacement of 70.2 mm at the cantilever end, accompanied by local buckling in the webs between transversal diaphragms and ribs. Due to the varying-thickness design, longitudinal strains were comparable between the middle section (thin plates) and the root section (thick plates) of the cantilever beam, showing a trend of an initial increase followed by a decrease from the end of the cantilever beam to the road centerline. Meanwhile, the cross-sections of the connection joint and concrete column transformed from overall compression to eccentric compression during the test. At the ultimate state, their steel structures remained elastic, with no obvious damage in the concrete or UHPC, verifying good load-bearing capacity. Furthermore, the finite element analysis showed the new connection joint and construction method of hinged-to-rigid could reduce the column top concrete compressive stress by 18–54%, tensile stress by 11–68%, and steel cap beam Mises stress by 10%. Finally, based on the experimental and numerical studies, the safety reserve coefficient of the new hybrid pier was over 2.7. Full article
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31 pages, 10806 KB  
Article
Study on the Mechanical Behavior of a Large-Segment Fully Prefabricated Subway Station During the Construction Process
by Zhongsheng Tan, Yuanzhuo Li, Xiaomin Fan and Jian Wang
Appl. Sci. 2025, 15(18), 9941; https://doi.org/10.3390/app15189941 - 11 Sep 2025
Viewed by 439
Abstract
In response to issues of long construction cycles, high pollution, and labor shortages in traditional cast in situ subway station construction, a refined 3D model of a large-segment prefabricated subway station was established using ABAQUS software 2024, with mechanical behavior throughout the construction [...] Read more.
In response to issues of long construction cycles, high pollution, and labor shortages in traditional cast in situ subway station construction, a refined 3D model of a large-segment prefabricated subway station was established using ABAQUS software 2024, with mechanical behavior throughout the construction process studied based on the Shenzhen Huaxia Station project case. The model incorporates a concrete inelastic damage constitutive model and a steel elastic–plastic model, accurately simulates key components, including dry joints of mortise–tenon grooves, prestressed reinforcement, and bolted connections, and implements a seven-phase construction sequence. Research findings indicate the following: (1) During component assembly, the roof vault settlement remains ≤3.8 mm, but backfilling significantly increases displacements (roof settlement reaches 45 mm, middle slab deflection measures 66.91 mm). (2) Longitudinal mortise–tenon joints develop stress concentrations due to stiffness disparities, with mid-column installation slots identified as vulnerable zones exhibiting maximum Von Mises stress of 32 MPa. (3) Mid-column eccentricity induces structural asymmetry, causing increased deflection in longer-span middle slabs, corbel contact stress differentials up to 6 MPa, and bolt tensile stresses exceeding 1.1 GPa. (4) The arched roof effectively transfers loads via three-hinged arch mechanisms, though spandrel horizontal displacement triggers 5 cm rebound in diaphragm wall displacement. Conclusions confirm overall the stability of the prefabricated structure while recommending the optimization of member stiffness matching, avoidance of asymmetric designs, and localized reinforcement for mortise–tenon edges and mid-column joints. Results provide valuable references for analogous projects. Full article
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4 pages, 2945 KB  
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Dynamic Digital Radiography in Ehlers–Danlos Syndrome: Visualizing Diaphragm Motility Impairment and Its Influence on Clinical Management
by Elisa Calabrò, Maurizio Cè, Francesca Lucrezia Rabaiotti, Laura Macrì and Michaela Cellina
Diagnostics 2025, 15(11), 1343; https://doi.org/10.3390/diagnostics15111343 - 27 May 2025
Cited by 1 | Viewed by 1645
Abstract
A 40-year-old woman with a known diagnosis of Ehlers–Danlos syndrome (EDS) began experiencing progressive shortness of breath and reduced exercise tolerance following her second pregnancy. The patient underwent an unenhanced computed tomography (CT) scan that showed a marked elevation of the left diaphragm. [...] Read more.
A 40-year-old woman with a known diagnosis of Ehlers–Danlos syndrome (EDS) began experiencing progressive shortness of breath and reduced exercise tolerance following her second pregnancy. The patient underwent an unenhanced computed tomography (CT) scan that showed a marked elevation of the left diaphragm. Suspecting diaphragm dysfunction, the patient underwent Dynamic Digital Radiography (DDR) that confirmed a reduction in left diaphragm motility, indicative of impaired diaphragm function. Based on the DDR findings, which demonstrated reduced but preserved diaphragmatic motion without paradoxical movement or complete immobility, the thoracic surgeon decided that surgical intervention, such as plication, was not necessary. Instead, rehabilitation exercises, including breathing techniques and diaphragm strengthening, were recommended. EDS includes connective tissue disorders that vary in severity but are typically characterized by hypermobility of the joints, skin hyper-elasticity, and a predisposition to vascular fragility. One of the complications of EDS is weakened connective tissues, which can affect the diaphragm, impairing the contractility of the muscle and leading to impaired mobility and respiratory symptoms such as shortness of breath. Diaphragm dysfunction can manifest as reduced movement, potentially related to the underlying connective tissue weakness. This case highlights the clinical value of DDR as a non-invasive, low-dose, and dynamic imaging modality in the diagnosis of diaphragmatic dysfunction in EDS patients, enabling individualized treatment planning and potentially avoiding unnecessary surgical interventions. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Respiratory Illnesses)
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20 pages, 7217 KB  
Article
The Field Monitoring and Numerical Simulation of Spatiotemporal Effects During Deep Excavation in Mucky Soft Soil: A Case Study
by Qiang Wu, Jianxiu Wang, Yanxia Long, Xuezeng Liu, Guanhong Long, Shuang Ding, Li Zhou, Huboqiang Li and Muhammad Akmal Hakim bin Hishammuddin
Appl. Sci. 2025, 15(4), 1992; https://doi.org/10.3390/app15041992 - 14 Feb 2025
Cited by 1 | Viewed by 1127
Abstract
The issue of geotechnical hazards induced by excavation in soft soil areas has become increasingly prominent. However, the retaining structure and surface settlement deformation induced by the creep of soft soil and spatial effect of the excavation sequence are not fully considered where [...] Read more.
The issue of geotechnical hazards induced by excavation in soft soil areas has become increasingly prominent. However, the retaining structure and surface settlement deformation induced by the creep of soft soil and spatial effect of the excavation sequence are not fully considered where only elastic–plastic deformation is used in design. To understand the spatiotemporal effects of excavation-induced deformation in soft soil pits, a case study was performed with the Huaxi Park Station of the Suzhou Metro Line S1, Jiangsu Province, China, as an example. Field monitoring was conducted, and a three-dimensional numerical model was developed, taking into account the creep characteristics of mucky clay and spatiotemporal response of retaining structures induced by excavations. The spatiotemporal effects in retaining structures and ground settlement during excavation processes were analyzed. The results show that as the excavation depth increased, the horizontal displacement of the diaphragm walls increased linearly and tended to exhibit abrupt changes when approaching the bottom of the pit. The maximum horizontal displacement of the wall at the west end well was close to 70 mm, and the maximum displacement of the wall at the standard section reached approximately 80 mm. The ground settlement on both pit sides showed a “trough” distribution pattern, peaking at about 12 m from the pit edge, with a settlement rate of −1.9 mm/m per meter of excavation depth. The excavation process directly led to the lateral deformation of the diaphragm walls, resulting in ground settlement, which prominently reflected the time-dependent deformation characteristics of mucky soft soil during the excavation process. These findings provide critical insights for similar deep excavation projects in mucky soft soil, particularly regarding excavation-induced deformations, by providing guidance on design standards and monitoring strategies for similar geological conditions. Full article
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19 pages, 13592 KB  
Article
Firefighting with Conductive Aerosol-Assisted Vortex Rings
by John LaRocco, Qudsia Tahmina, Stanley Essel and John Simonis
Technologies 2025, 13(1), 10; https://doi.org/10.3390/technologies13010010 - 27 Dec 2024
Cited by 1 | Viewed by 4609
Abstract
Conventional firefighting tools and methods can strain water sources, require toxic foams, or rely on pre-installed countermeasures. A low-cost, non-toxic, and portable option was previously overlooked in portable devices: electrically assisted “ionic wind” fire suppression. Conductive aerosols, carried by vortex rings, can potentially [...] Read more.
Conventional firefighting tools and methods can strain water sources, require toxic foams, or rely on pre-installed countermeasures. A low-cost, non-toxic, and portable option was previously overlooked in portable devices: electrically assisted “ionic wind” fire suppression. Conductive aerosols, carried by vortex rings, can potentially extend the length of an electric arc and suppress fires. After the simulation, two prototype vortex ring launchers were compared, one using compressed air and another using an elastic diaphragm. The efficiency of each test case was assessed with a purpose-built automated image analysis system. The compressed air vortex launcher had a significantly higher efficiency than the elastic diaphragm prototype, with a p-value of 0.0006. Regardless of the prototype or the use of conductive aerosols, the device had an effective range of up to 1.98 m. The highest reliability of 90 ± 4.1% was achieved at 1.52 m from the launcher. The observations with compressed air launcher results saw no significant difference regarding the use of the conductive aerosol. Further investigation of the concept requires a systematic examination of other types of fires, electronic optimization, permutations of chemicals and concentrations, other types of vortex generation, and human factors. The computer vision system could also be used to further detect and target active fires. Beyond firefighting, the device can be adapted to applications ranging from manufacturing to aerospace. Regardless of the use of conductive aerosols, handheld vortex ring generators are a versatile, potential firefighting tool. Full article
(This article belongs to the Section Environmental Technology)
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12 pages, 659 KB  
Article
The Impact of Pneumoperitoneum on Mean Expiratory Flow Rate: Observational Insights from Patients with Healthy Lungs
by Lajos Bogár, Kamilla Domokos, Csaba Csontos and Balázs Sütő
Diagnostics 2024, 14(21), 2375; https://doi.org/10.3390/diagnostics14212375 - 24 Oct 2024
Cited by 3 | Viewed by 1997
Abstract
Background/Objectives: Surgical pneumoperitoneum (PP) significantly impacts volume-controlled ventilation, characterized by reduced respiratory compliance, elevated peak inspiratory pressure, and an accelerated expiratory phase due to an earlier onset of the airway pressure gradient. We hypothesized that this would shorten expiratory time, potentially increasing expiratory [...] Read more.
Background/Objectives: Surgical pneumoperitoneum (PP) significantly impacts volume-controlled ventilation, characterized by reduced respiratory compliance, elevated peak inspiratory pressure, and an accelerated expiratory phase due to an earlier onset of the airway pressure gradient. We hypothesized that this would shorten expiratory time, potentially increasing expiratory flow rate compared to pneumoperitoneum conditions. Calculations were performed to establish correlations between respiratory parameters and the mean increase in expiratory flow rate relative to baseline. Methods: Mechanical ventilation parameters were recorded for 67 patients both pre- and post-PP. Ventilator settings were standardized with a tidal volume of 6 mL/kg, a respiratory rate of 12 breaths per minute, a PEEP of 3 cmH2O, an inspiratory time of 2 s, and an inspiratory-to-expiratory ratio of 1:1.5 (I:E). Results: The application of PP increased both peak inspiratory pressure and mean expiratory flow rate by 28% compared to baseline levels. The elevated intra-abdominal pressure of 20 cmH2O resulted in a 34% reduction in dynamic chest compliance, a 50% increase in elastance, and a 20% increase in airway resistance. The mean expiratory flow rate increments relative to baseline showed a significant negative correlation with elastance (p = 0.0119) and a positive correlation with dynamic compliance (p = 0.0028) and resistance (p = 0.0240). Conclusions: A PP of 20 cmH2O resulted in an increase in the mean expiratory flow rate in the conventional I:E ratio in the volume-ventilated mode. PP reduces lung and chest wall compliance by elevating the diaphragm, compressing the thoracic cavity, and increasing airway pressures. Consequently, the lungs and chest wall stiffen, requiring greater ventilatory effort and accelerating expiratory flow due to increased airway resistance and altered pulmonary mechanics. Prolonging the inspiratory phase through I:E ratio adjustment helps maintain peak inspiratory pressures closer to baseline levels, and this method enhances the safety and efficacy of mechanical ventilation in maintaining optimal respiratory function during laparoscopic surgery. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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14 pages, 5519 KB  
Article
Numerical Simulation of the Flow Field Stabilization of a Pressure-Regulating Device
by Chao Chen, Yanyan Zhao, Junping Liu, Yuxia Zhao, Zawar Hussain and Rongjun Xie
Agriculture 2024, 14(11), 1873; https://doi.org/10.3390/agriculture14111873 - 23 Oct 2024
Cited by 4 | Viewed by 1132
Abstract
In sprinkler irrigation systems in hilly areas, pressure-regulating devices can improve the uneven pressure distribution on branch pipes and consequently improve the irrigation uniformity. A pressure-regulating device for sprinkler irrigation systems was developed; the variation characteristics of the internal pressure field and velocity [...] Read more.
In sprinkler irrigation systems in hilly areas, pressure-regulating devices can improve the uneven pressure distribution on branch pipes and consequently improve the irrigation uniformity. A pressure-regulating device for sprinkler irrigation systems was developed; the variation characteristics of the internal pressure field and velocity field distribution over time, variation law of the elastic diaphragm of the pressure-regulating device with respect to the inlet pressure, and pressure-regulating and flow stabilizing mechanisms were assessed. The results show that the pressure regulation and flow stabilization of the pressure-regulating device were affected by the deformation of the elastic diaphragm. When the elastic diaphragm deforms, the main factors of pressure regulation and flow stabilization in the pressure regulation device gradually shift from the side channel and compensation chamber to the side channel and secondary channel. The channel structure plays a crucial role in the entire fluid system. A comparison and analysis of the changes in cross-sectional pressure and flow velocity of the flow channel under different inlet pressures revealed that increasing the height of the side flow channel baffle and auxiliary flow channel effectively improved the pressure-regulating and flow-stabilizing performance of the pressure-regulating device. The results can be useful to optimize the structure of pressure regulation devices and to solve the problem of excessive pressure deviation in sprinkler irrigation systems in hilly areas. Full article
(This article belongs to the Section Agricultural Technology)
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12 pages, 2215 KB  
Article
Effect of Bamboo Nodes on the Mechanical Properties of Phyllostachys iridescens
by Xuehua Wang, Siyuan Yu, Shuotong Deng, Ru Xu, Qi Chen and Pingping Xu
Forests 2024, 15(10), 1740; https://doi.org/10.3390/f15101740 - 2 Oct 2024
Cited by 7 | Viewed by 2427
Abstract
Bamboo is a significant natural resource, recognized for its rapid growth, lightweight composition, high strength, and excellent mechanical properties, making it increasingly valuable in the furniture and construction industries. A critical structural aspect of bamboo is its nodes, yet there has been limited [...] Read more.
Bamboo is a significant natural resource, recognized for its rapid growth, lightweight composition, high strength, and excellent mechanical properties, making it increasingly valuable in the furniture and construction industries. A critical structural aspect of bamboo is its nodes, yet there has been limited research on their impact on bamboo’s mechanical properties. This study investigates the mechanical properties of round bamboo tubes in three different states: internodes (S1), nodes with diaphragm removed (S2), and nodes with diaphragm (S3). The results show that the mechanical properties of S1 are a compressive strength (CS) of 29.72 MPa, a shear strength parallel to grain (SSp) of 11.82 MPa, a radial stiffness (Sr) of 155.59 MPa, an impact toughness (IT) of 20.74 kJ/m2, a modulus of rupture (MOR) of 16.45 MPa, a modulus of elasticity (MOE) of 408.53 MPa, a tensile modulus of rupture parallel to grain (MORT) of 189.62 MPa, and a tensile modulus of elasticity parallel to grain (MOET) of 431.05 MPa. Compared with S1, these above parameters change by CS +11%, SSp 6%, Sr +100%, IT −29%, MOR +5%, MOE +63%, MORT −29%, and MOET −58% in S2 and CS +10%, SSp 28%, Sr +250%, IT −31%, MOR +28%, MOE +92%, MORT −25%, and MOET −42% in S3. It demonstrates that the bamboo diaphragm and nodes significantly influence the mechanical properties of bamboo; they have a significant positive effect on the bending properties across the transverse grain, radial ring stiffness, and shear properties along the grain, but negatively impact the tensile properties along the grain. Full article
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22 pages, 14713 KB  
Article
A Proposed Non-Destructive Method Based on Sphere Launching and Piezoelectric Diaphragm
by Cristiano Soares Junior, Paulo Roberto Aguiar, Doriana M. D’Addona, Pedro Oliveira Conceição Junior and Reinaldo Götz Oliveira Junior
Sensors 2024, 24(18), 5874; https://doi.org/10.3390/s24185874 - 10 Sep 2024
Viewed by 1038
Abstract
This work presents the study of a reproducible acoustic emission method based on the launching of a metallic sphere and low-cost piezoelectric diaphragm. For this purpose, tests were first conducted on a carbon fiber-reinforced polymer structure, and then on an aluminum structure for [...] Read more.
This work presents the study of a reproducible acoustic emission method based on the launching of a metallic sphere and low-cost piezoelectric diaphragm. For this purpose, tests were first conducted on a carbon fiber-reinforced polymer structure, and then on an aluminum structure for comparative analysis. The pencil-lead break (PLB) tests were also conducted for comparisons with the proposed method. Different launching heights and elastic deformations of the structures were investigated. The results show higher repeatability for the sphere impact method, as the PLB is more affected by human inaccuracy, and it was also effective in damage detection. Full article
(This article belongs to the Special Issue Feature Papers in Physical Sensors 2024)
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21 pages, 3404 KB  
Article
Reinforcement of Insufficient Transverse Connectivity in Prestressed Concrete Box Girder Bridges Using Concrete-Filled Steel Tube Trusses and Diaphragms: A Comparative Study
by Peng Li, Caiqian Yang, Fu Xu, Junshi Li and Dongzhao Jin
Buildings 2024, 14(8), 2466; https://doi.org/10.3390/buildings14082466 - 9 Aug 2024
Cited by 10 | Viewed by 1962
Abstract
To address the issue of insufficient transverse connectivity in prestressed concrete box girder (PCB) bridges, this study investigates two transverse strengthening methods—installing diaphragms and utilizing concrete-filled steel tube trusses (CFSTTs). A finite element model was developed for a typical 30 m PCB bridge [...] Read more.
To address the issue of insufficient transverse connectivity in prestressed concrete box girder (PCB) bridges, this study investigates two transverse strengthening methods—installing diaphragms and utilizing concrete-filled steel tube trusses (CFSTTs). A finite element model was developed for a typical 30 m PCB bridge and was validated by on-site load test results for reliability. Based on the deflection and load distribution of PCB bridges before and after reinforcement, as well as the maximum stress and strain of the diaphragms and the CFSTTs, comparative analyses were conducted on diaphragms of different thicknesses and materials, as well as on CFSTTs of various strength grades. The results show that the addition of a transverse partition and CFSTTs can effectively improve the load distribution of the PCB bridge and reduce the maximum deflection of the girder, especially when using the CFSTT reinforcement method. The unique structural design improves the reinforcement effect of the material in the post-elastic stage. When using CFSTTs, increasing the steel tube wall strength significantly reduces the maximum deflection of the main girder. For example, using steel tubes with yield strengths of 235 MPa and 420 MPa filled with concrete of 50 MPa compressive strength reduced the maximum deflections by 15.32% and 24.55%, respectively, and improved the load distribution coefficients by up to 7.31% and 11.57%. Additionally, steel diaphragms demonstrated better reinforcement effects compared with concrete diaphragms. The load transverse distribution coefficients for the CFSTT-reinforced PCB bridge were calculated using the hinge plate (beam) and the rigid plate (beam) methods, showing minimal differences between the two approaches. The findings of this study provide valuable insights into the design of diaphragm and CFSTT reinforcement in PCB bridges, aiding in the selection of optimal reinforcement strategies. Full article
(This article belongs to the Section Building Structures)
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22 pages, 13462 KB  
Article
Displacement Analyses of Diaphragm Wall in Small-Scale Deep Excavation Considering Joints between Panels
by Ming Yang, Rongxing Wu, Chenxi Tong, Jianwei Chen and Bing Tang
Buildings 2024, 14(5), 1449; https://doi.org/10.3390/buildings14051449 - 16 May 2024
Cited by 4 | Viewed by 2289
Abstract
This paper proposed a new method for modelling joints, using anisotropic plate elements and elastic bar elements to address the issue that joints between panels are usually disregarded in numerical modelling. For small-scale deep excavations, which are frequently performed in the construction of [...] Read more.
This paper proposed a new method for modelling joints, using anisotropic plate elements and elastic bar elements to address the issue that joints between panels are usually disregarded in numerical modelling. For small-scale deep excavations, which are frequently performed in the construction of various working shafts but have not been sufficiently studied, two numerical models were developed, using the No.1 Shaft of Tongtu Road Utility Tunnel in Ningbo, China, as a research object. One model considered the joints between the panels as proposed, while the other disregarded the joints as conventional. In comparison to the conventional method, the proposed method was validated due to yielding wall displacements that closely matched the results of the field monitoring, with a notable reduction in the error observed in the calculated displacements for the short side of the excavation. Furthermore, 34 numerical models were developed in order to investigate the influence of excavation length, depth, and diaphragm wall thickness on the relative differences between the calculated displacements obtained by the two models. The results of this study can provide references for the development of finite element models for designing small-scale deep excavation. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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21 pages, 5677 KB  
Article
Theoretical Study on Diaphragm Wall and Surface Deformation Due to Foundation Excavation Based on Three-Parameter Kerr Model
by Kunpeng Li, Shihai Chen, Rupeng Pei and Yangcai Li
Sustainability 2024, 16(6), 2295; https://doi.org/10.3390/su16062295 - 10 Mar 2024
Cited by 3 | Viewed by 1740
Abstract
To calculate the horizontal displacement of the diaphragm wall and surface settlement caused by foundation pit excavation, the three-parameter Kerr foundation model was applied to a diaphragm wall and derived the flexural differential equations of the diaphragm wall and calculated the horizontal displacement [...] Read more.
To calculate the horizontal displacement of the diaphragm wall and surface settlement caused by foundation pit excavation, the three-parameter Kerr foundation model was applied to a diaphragm wall and derived the flexural differential equations of the diaphragm wall and calculated the horizontal displacement of the diaphragm wall using the finite difference calculation method. The boundary element method combined with the Mindlin displacement solution was then used to invert the additional horizontal stress near the diaphragm wall. Lastly, the Mindlin solution was used to calculate the surface settlement. The effectiveness of the proposed calculation method was verified by comparing the horizontal displacement of the diaphragm wall and the surface settlement between the theoretical calculation and the actual project. The theory proves that there is a certain connection between the horizontal displacement of the diaphragm wall and the surface settlement, and the horizontal displacement of the diaphragm wall is larger than the surface settlement. Using this theory to further analyze the foundation pit construction parameters, the greater the thickness and elasticity modulus of the diaphragm wall, and the greater the diameter and number of internal supports, the smaller the horizontal displacement of the diaphragm wall and the surface settlement. The theory can accurately predict the horizontal displacement of the diaphragm wall and surface settlement and provides guidance for the construction of foundation pit projects. Full article
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12 pages, 5445 KB  
Article
The Fabrication and Evaluation of a Capacitive Pressure Sensor Using Ru-Based Thin Film Metallic Glass with Structural Relaxation by Heat Treatment
by Hodaka Otsuka, Takafumi Ninoseki, Chiemi Oka, Seiichi Hata and Junpei Sakurai
Sensors 2023, 23(23), 9557; https://doi.org/10.3390/s23239557 - 1 Dec 2023
Cited by 1 | Viewed by 3076
Abstract
Microelectromechanical systems (MEMS)-based capacitive pressure sensors are conventionally fabricated from diaphragms made of Si, which has a high elastic modulus that limits the control of internal stress and constrains size reduction and low-pressure measurements. Ru-based thin-film metallic glass (TFMG) exhibits a low elastic [...] Read more.
Microelectromechanical systems (MEMS)-based capacitive pressure sensors are conventionally fabricated from diaphragms made of Si, which has a high elastic modulus that limits the control of internal stress and constrains size reduction and low-pressure measurements. Ru-based thin-film metallic glass (TFMG) exhibits a low elastic modulus, and the internal stress can be controlled by heat treatment, so it may be a suitable diaphragm material for facilitating size reduction of the sensor without performance degradation. In this study, a Ru-based TFMG was used to realize a flattened diaphragm, and structural relaxation was achieved through annealing at 310 °C for 1 h in a vacuum. The diaphragm easily deformed, even under low differential pressure, when reduced in size. A diaphragm with a diameter of 1.7 mm was then applied to successfully fabricate a capacitive pressure sensor with a sensor size of 2.4 mm2. The sensor exhibited a linearity of ±3.70% full scale and a sensitivity of 0.09 fF/Pa in the differential pressure range of 0–500 Pa. Full article
(This article belongs to the Special Issue Feature Papers in Physical Sensors 2023)
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19 pages, 6089 KB  
Article
Semi-Analytical Prediction of Ground Surface Heave Induced by Shield Tunneling Considering Three-Dimensional Space Effect
by Jianfeng Qi, Guohua Zhang, Yuyong Jiao, Luyi Shen, Fei Zheng, Junpeng Zou and Peng Zhang
Appl. Sci. 2023, 13(20), 11588; https://doi.org/10.3390/app132011588 - 23 Oct 2023
Cited by 2 | Viewed by 1393
Abstract
The ground surface deformation induced by shield tunnels passing through enclosure structures of existing tunnels is a particular underground construction scenario that has been encountered in Wuhan Metro Line 12 engineering cases in China. Timely ground deformation prediction is important to keep shield [...] Read more.
The ground surface deformation induced by shield tunnels passing through enclosure structures of existing tunnels is a particular underground construction scenario that has been encountered in Wuhan Metro Line 12 engineering cases in China. Timely ground deformation prediction is important to keep shield tunneling safe. However, the classic ground deformation theory is difficult to accurately predict for this ground deformation. This paper develops a semi-analytical method to predict ground heave considering the space effect in this engineering condition. Based on the improved ground deformation theory, a novel deformation prediction method for the ground and enclosure structure is derived and combined with Kirchhoff plate theory. Comparing with field deformation measurements, the maximum difference between the measured and calculated deformation is 14.6%, which demonstrates that the proposed method can be used to predict the ground heave induced by shield tunnels passing through the enclosure structure of existing tunnels. The parameters of the underground diaphragm wall used in Wuhan Metro Line 12 are further studied in detail. The results show that the ground heaves have a positive correlation with the embedded ratio of the diaphragm wall, but a negative correlation with its elastic modulus and thickness. However, the thickness and embedded ratio have a limited effect on ground heaves. This study provides a technical reference for optimizing the setting of enclosure structures in order to protect existing buildings. Full article
(This article belongs to the Section Civil Engineering)
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35 pages, 9137 KB  
Review
Extracellular Matrix Proteomics: The mdx-4cv Mouse Diaphragm as a Surrogate for Studying Myofibrosis in Dystrophinopathy
by Paul Dowling, Stephen Gargan, Margit Zweyer, Dieter Swandulla and Kay Ohlendieck
Biomolecules 2023, 13(7), 1108; https://doi.org/10.3390/biom13071108 - 12 Jul 2023
Cited by 11 | Viewed by 4489
Abstract
The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic changes and reduced tissue elasticity correlate with the loss in motor function in this X-chromosomal disorder. Thus, although dystrophinopathies are due [...] Read more.
The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic changes and reduced tissue elasticity correlate with the loss in motor function in this X-chromosomal disorder. Thus, although dystrophinopathies are due to primary abnormalities in the DMD gene causing the almost-complete absence of the cytoskeletal Dp427-M isoform of dystrophin in voluntary muscles, the excessive accumulation of extracellular matrix proteins presents a key histopathological hallmark of muscular dystrophy. Animal model research has been instrumental in the characterization of dystrophic muscles and has contributed to a better understanding of the complex pathogenesis of dystrophinopathies, the discovery of new disease biomarkers, and the testing of novel therapeutic strategies. In this article, we review how mass-spectrometry-based proteomics can be used to study changes in key components of the endomysium, perimysium, and epimysium, such as collagens, proteoglycans, matricellular proteins, and adhesion receptors. The mdx-4cv mouse diaphragm displays severe myofibrosis, making it an ideal model system for large-scale surveys of systematic alterations in the matrisome of dystrophic fibers. Novel biomarkers of myofibrosis can now be tested for their appropriateness in the preclinical and clinical setting as diagnostic, pharmacodynamic, prognostic, and/or therapeutic monitoring indicators. Full article
(This article belongs to the Special Issue Muscular Dystrophy: From Molecular Basis to Therapies)
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