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55,804 Results Found

  • Article
  • Open Access
32 Citations
4,962 Views
24 Pages

25 February 2021

Teachers’ diagnostic competences are essential with respect to student achievement, classroom assessment, and instructional quality. Important components of diagnostic competences are teachers’ professional knowledge including content knowledge (CK),...

  • Article
  • Open Access
53 Citations
7,496 Views
14 Pages

Diagnostic Process in Rare Diseases: Determinants Associated with Diagnostic Delay

  • Juan Benito-Lozano,
  • Greta Arias-Merino,
  • Mario Gómez-Martínez,
  • Alba Ancochea-Díaz,
  • Aitor Aparicio-García,
  • Manuel Posada de la Paz and
  • Verónica Alonso-Ferreira

Many people living with rare disease (RD) report a difficult diagnostic process from the symptom onset until they obtain the definitive diagnosis. The aim of this study was thus to ascertain the diagnostic process in RDs, and explore the determinants...

  • Review
  • Open Access
1 Citations
2,739 Views
11 Pages

20 July 2024

Pregnancy-related morbidity and mortality remain high across the United States, with the majority of deaths being deemed preventable. Misdiagnosis and delay in diagnosis are thought to be significant contributors to preventable harm. These diagnostic...

  • Systematic Review
  • Open Access
13 Citations
3,079 Views
19 Pages

13 August 2022

Antimicrobial resistance is a growing public health crisis, propelled by inappropriate antibiotic prescription, in particular the over-prescription of antibiotics, prolonged duration of antibiotic therapy and the overuse of broad-spectrum antibiotics...

  • Article
  • Open Access
2 Citations
3,010 Views
16 Pages

The research refers to the modeling of the meaningful and relatively stable visual-figurative and verbal-sign representation of real problems in medical diagnostics of the human organs and systems. The core results of the research are presented. Here...

  • Article
  • Open Access
3 Citations
2,813 Views
12 Pages

Proposal and Validation of New Diagnostic Criteria for Diagnostic Weights of Endoultrasonographic Findings for Early Chronic Pancreatitis

  • Ken Kashima,
  • Akira Yamamiya,
  • Yoko Abe,
  • Kazunori Nagashima,
  • Takahito Minaguchi,
  • Yasuhito Kunogi,
  • Fumi Sakuma,
  • Koh Fukushi,
  • Yasunori Inaba and
  • Atsushi Irisawa
  • + 3 authors

16 August 2023

[Background and study aim] A commonly applied method for diagnosing chronic pancreatitis (CP) uses endoscopic ultrasonography (EUS), assigning weights to each EUS diagnostic finding. It is the Rosemont classification (RC). In 2019, to improve EUS dia...

  • Article
  • Open Access
502 Views
9 Pages

A TRAb-First Diagnostic Strategy for Overt Hyperthyroidism: Diagnostic Performance and Implications for Reflex Testing

  • Petra Petranović Ovčariček,
  • Alfredo Campennì,
  • Federica D’Aurizio,
  • Rosaria Maddalena Ruggeri and
  • Luca Giovanella

6 January 2026

Background/Objectives: To evaluate whether a TSH-receptor antibody (TRAb)-first, one-sample diagnostic strategy improves etiologic classification of overt hyperthyroidism compared with conventional pathways, and to assess its implications for imaging...

  • Review
  • Open Access
7 Citations
4,709 Views
19 Pages

Innovative Diagnostic Solutions in Hemostasis

  • Emmanuel J. Favaloro and
  • Leonardo Pasalic

11 November 2024

Hemostasis describes the process of blood clotting homeostasis. Hemostasis reflects a balance of procoagulant and anticoagulant mechanisms that aim to prevent both bleeding and thrombosis. If hemostasis is disrupted, and bleeding or thrombosis occur,...

  • Article
  • Open Access
11 Citations
4,478 Views
36 Pages

27 February 2021

Screening and diagnostic tests are applied for the classification of people into diseased and non-diseased populations. Although diagnostic accuracy measures are used to evaluate the correctness of classification in clinical research and practice, th...

  • Review
  • Open Access
521 Views
14 Pages

Diagnostic Accuracy of Utilizing Artificial Intelligence for Malaria Diagnostic: A Systematic Review and Meta-Analysis

  • Icha Farihah Deniyati Faratisha,
  • Khadijah Cahya Yunita,
  • Hanifa Rizky Rahmawati,
  • Loeki Enggar Fitri,
  • Nuning Winaris and
  • Lailil Muflikah

Background: Malaria remains a major public health concern around the world. Microscopic blood smear examination continues to be the gold standard for diagnosis; however, it requires high technical skills and expertise, limiting diagnostic accuracy in...

  • Article
  • Open Access
58 Citations
3,527 Views
19 Pages

Analysis of Diagnostic Methods and Energy of Production Systems Drives

  • Ivan Kuric,
  • Ivana Klačková,
  • Yury Rafailovich Nikitin,
  • Ivan Zajačko,
  • Miroslav Císar and
  • Karol Tucki

12 May 2021

This article deals with solving the urgent scientific problem of the diagnostics of drives of technological robotized workplaces with support of sensors. The dependence of diagnostic parameters on the technical state of drives of automated technologi...

  • Article
  • Open Access
3 Citations
4,304 Views
14 Pages

The European Union In Vitro Diagnostic Medical Devices Regulation (EU) 2017/746 (IVDR) introduces companion diagnostics (CDx) as a new legal term. CDx are applied in combination with a medicinal product to identify patient subgroups most likely to be...

  • Article
  • Open Access
5 Citations
4,215 Views
14 Pages

A Systematic Approach to Diagnostic Laboratory Software Requirements Analysis

  • Thomas Krause,
  • Elena Jolkver,
  • Paul Mc Kevitt,
  • Michael Kramer and
  • Matthias Hemmje

Genetics plays an ever-increasing role in medical diagnostics. The requirements for laboratory diagnostics are constantly changing due to new emerging diagnostic procedures, methodologies, devices, and regulatory requirements. Standard software alrea...

  • Article
  • Open Access
28 Citations
16,902 Views
19 Pages

COVID-19 Impact on Diagnostic Innovations: Emerging Trends and Implications

  • Anne O. Oyewole,
  • Lucy Barrass,
  • Emily G. Robertson,
  • James Woltmann,
  • Hannah O’Keefe,
  • Harsimran Sarpal,
  • Kim Dangova,
  • Catherine Richmond and
  • Dawn Craig

Diagnostic testing remains the backbone of the coronavirus disease 2019 (COVID-19) response, supporting containment efforts to mitigate the outbreak. The severity of this crisis and increasing capacity issues associated with polymerase chain reaction...

  • Review
  • Open Access
14 Citations
8,570 Views
40 Pages

Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies

  • Linda P. Guaman-Bautista,
  • Erick Moreta-Urbano,
  • Claudia G. Oña-Arias,
  • Marbel Torres-Arias,
  • Nikolaos C. Kyriakidis,
  • Koray Malcı,
  • Nestor Jonguitud-Borrego,
  • Leonardo Rios-Solis,
  • Espiridion Ramos-Martinez and
  • Carlos Barba-Ostria
  • + 1 author

26 October 2021

The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respira...

  • Editorial
  • Open Access
6 Citations
6,503 Views
3 Pages

There is no doubt about the importance of diagnostic testing in an emergency; specifically, which range of tests is available, where and when they are dispensed, and who might be tested using laboratory-developed tests, or other diagnostic tests incl...

  • Article
  • Open Access
7 Citations
4,455 Views
24 Pages

Screening and diagnostic tests are used to classify people with and without a disease. Diagnostic accuracy measures are used to evaluate the correctness of a classification in clinical research and practice. Although this depends on the uncertainty o...

  • Article
  • Open Access
9 Citations
1,828 Views
14 Pages

5 March 2024

The AC drive is an important component and the most common element of any manufacturing process. A particularly serious task is the proper assessment of the AC drive’s technical condition, as its failure can cause problems for entire units and...

  • Commentary
  • Open Access
2,226 Views
5 Pages

26 January 2022

Over the past decade, the secondary analysis of existing DNA datasets for clinical resulting has become an established practice. However, this established practice is typically limited to only one category of secondary genomic findings, the identific...

  • Communication
  • Open Access
1,051 Views
8 Pages

Brucella Diagnostics in Endemic Areas: Evaluation of Point-of-Care Kits and the Need for Alternative Diagnostic Tests

  • Aggrey Keya,
  • Pauline Gitonga,
  • Daniel Wanjohi,
  • Esther Lemarkoko,
  • Joseph Sankok,
  • Brian Ogoti,
  • Angela Bosco-Lauth,
  • Marybeth Maritim,
  • George Gitao and
  • Richard Bowen
  • + 2 authors

Brucellosis is a significant public health challenge in Kenya, particularly in pastoralist communities where the disease is endemic. Reliable and accurate point-of-care diagnostics are essential for timely case identification and effective disease ma...

  • Review
  • Open Access
198 Citations
20,175 Views
50 Pages

Novel Diagnostic Biomarkers in Colorectal Cancer

  • Aneta L. Zygulska and
  • Piotr Pierzchalski

Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease associated with a number of genetic or somatic mutations. Diagnostic...

  • Article
  • Open Access
32 Citations
4,772 Views
12 Pages

Frequency and Duration of, and Risk Factors for, Diagnostic Delays Associated with Histoplasmosis

  • Aaron C. Miller,
  • Alan T. Arakkal,
  • Scott H. Koeneman,
  • Joseph E. Cavanaugh,
  • George R. Thompson,
  • John W. Baddley and
  • Philip M. Polgreen

23 April 2022

Histoplasmosis is often confused with other diseases leading to diagnostic delays. We estimated the incidence, length of, and risk factors for, diagnostic delays associated with histoplasmosis. Using data from IBM Marketscan, 2001–2017, we foun...

  • Review
  • Open Access
6 Citations
5,334 Views
21 Pages

Diagnostic Approaches in Myeloid Sarcoma

  • Elzbieta Patkowska,
  • Agnieszka Krzywdzinska,
  • Iwona Solarska,
  • Magdalena Wojtas and
  • Monika Prochorec-Sobieszek

Myeloid sarcoma (MS), or extramedullary acute myeloid leukaemia tumour (eAML), is a rare hematopoietic neoplasm. Recognised as a distinct entity within acute myeloid leukaemia (AML), MS presents significant diagnostic challenges due to its rarity, cl...

  • Article
  • Open Access
2,317 Views
12 Pages

Could Vaspin Be a Potential Diagnostic Marker in Endometrial Cancer?

  • Dominika Pietrzyk,
  • Piotr Tkacz,
  • Mateusz Kozłowski,
  • Sebastian Kwiatkowski,
  • Małgorzata Rychlicka,
  • Ewa Pius-Sadowska,
  • Bogusław Machaliński and
  • Aneta Cymbaluk-Płoska

Obesity and being overweight are risk factors for many types of cancer, including endometrial cancer. Adipose tissue is thought to be an endocrine organ that produces various hormones, including one known as vaspin. Insulin resistance, metabolic synd...

  • Review
  • Open Access
968 Views
42 Pages

Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors

  • Carol Yen,
  • John W. Epling,
  • Michelle Rockwell and
  • Monifa Vaughn-Cooke

Diagnostic errors have been a critical concern in healthcare, leading to substantial financial burdens and serious threats to patient safety. The Improving Diagnosis in Health Care report by the National Academies of Sciences, Engineering, and Medici...

  • Review
  • Open Access
2 Citations
5,275 Views
12 Pages

Neurocysticercosis—Diagnostic Mystery: Current Status for Europe

  • Mikołaj Hurła,
  • Damian Pikor,
  • Klaudia Kościelecka,
  • Alicja Drelichowska,
  • Natalia Banaszek and
  • Małgorzata Paul

29 August 2024

Neurocysticercosis (NCC), a parasitic infection of the central nervous system caused by the larval stage of Taenia solium, presents a diagnostic conundrum due to its rare and often nonspecific clinical manifestations. This paper aims to unravel the d...

  • Article
  • Open Access
10 Citations
2,922 Views
14 Pages

13 November 2022

Most horses affected by headshaking (HS) are diagnosed with idiopathic trigeminal-mediated headshaking (i-TMHS) when no underlying disease is found. Diagnosis is made by the exclusion of differentials considering history, clinical signs, and diagnost...

  • Review
  • Open Access
54 Citations
8,630 Views
23 Pages

Optical Diagnostic Based on Functionalized Gold Nanoparticles

  • Jiemei Ou,
  • Zidan Zhou,
  • Zhong Chen and
  • Huijun Tan

5 September 2019

Au nanoparticles (NPs) possess unique physicochemical and optical properties, showing great potential in biomedical applications. Diagnostic spectroscopy utilizing varied Au NPs has become a precision tool of in vitro and in vivo diagnostic for cance...

  • Review
  • Open Access
5 Citations
8,389 Views
12 Pages

Molecular Diagnostic Applications in Colorectal Cancer

  • Laura Huth,
  • Jörg Jäkel and
  • Edgar Dahl

Colorectal cancer, a clinically diverse disease, is a leading cause of cancer-related death worldwide. Application of novel molecular diagnostic tests, which are summarized in this article, may lead to an improved survival of colorectal cancer patien...

  • Review
  • Open Access
18 Citations
6,941 Views
20 Pages

14 January 2020

The fundamental information theory functions of entropy, relative entropy, and mutual information are directly applicable to clinical diagnostic testing. This is a consequence of the fact that an individual’s disease state and diagnostic test r...

  • Review
  • Open Access
73 Citations
8,508 Views
11 Pages

The Challenges of Diagnostic Imaging in the Era of Big Data

  • Marco Aiello,
  • Carlo Cavaliere,
  • Antonio D’Albore and
  • Marco Salvatore

The diagnostic imaging field has undergone considerable growth both in terms of technological development and market expansion; with the following increasing production of a considerable amount of data that potentially fully poses diagnostic imaging...

  • Review
  • Open Access
51 Citations
13,604 Views
23 Pages

Diagnostic Applications of Intraoral Scanners: A Systematic Review

  • Francesca Angelone,
  • Alfonso Maria Ponsiglione,
  • Carlo Ricciardi,
  • Giuseppe Cesarelli,
  • Mario Sansone and
  • Francesco Amato

In addition to their recognized value for obtaining 3D digital dental models, intraoral scanners (IOSs) have recently been proven to be promising tools for oral health diagnostics. In this work, the most recent literature on IOSs was reviewed with a...

  • Article
  • Open Access
5 Citations
3,755 Views
21 Pages

1 February 2022

During the process of disease diagnosis, overdiagnosis can lead to potential health loss and unnecessary anxiety for patients as well as increased medical costs, while underdiagnosis can result in patients not being treated on time. To deal with thes...

  • Commentary
  • Open Access
15 Citations
4,517 Views
6 Pages

CRISPR-Based Diagnostics: A Potential Tool to Address the Diagnostic Challenges of Tuberculosis

  • Yong Qi,
  • Kun Li,
  • Yuxi Li,
  • Donglin Guo,
  • Jing Xu,
  • Yuexi Li and
  • Wenping Gong

20 October 2022

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which infects more than 23% of the world’s population. With the emergence of drug-resistant TB (DR-TB) and latent TB infection (LTBI), rapid diagnosis of DR-TB and...

  • Article
  • Open Access
2 Citations
985 Views
28 Pages

Sex-Based Disparities in Clinical Burden and Diagnostic Delay in COPD: Insights from Primary Care

  • Myriam Calle Rubio,
  • Soha Esmaili,
  • Iman Esmaili,
  • Lucia Gómez Martín-Caro,
  • Sofia Ayat Ortiz and
  • Juan Luis Rodríguez Hermosa

4 September 2025

Background. Sex-based disparities in chronic obstructive pulmonary disease (COPD) diagnosis remain underexplored, particularly in primary care settings. This study assessed sex differences in clinical burden, diagnostic delay, and missed diagnostic o...

  • Article
  • Open Access
21 Citations
4,152 Views
11 Pages

Training in Diagnostic Hysteroscopy: The “Arbor Vitae” Method

  • Ivan Mazzon,
  • Andrea Etrusco,
  • Antonio Simone Laganà,
  • Vito Chiantera,
  • Silvia Di Angelo Antonio,
  • Valentina Tosto,
  • Sandro Gerli and
  • Alessandro Favilli

24 May 2023

Background and Objectives: Diagnostic hysteroscopy is the gold standard in the diagnosis of intrauterine pathology and is becoming an essential tool in the daily practice of gynecology. Training programs for physicians are necessary to ensure adequat...

  • Feature Paper
  • Review
  • Open Access
58 Citations
10,449 Views
14 Pages

Lanthanide-Doped Nanoparticles for Diagnostic Sensing

  • Song Yeul Lee,
  • Min Lin,
  • Aeju Lee and
  • Yong Il Park

23 November 2017

Lanthanide-doped nanoparticles exhibit unique optical properties, such as a long luminescence lifetime (up to several milliseconds), sharp emission peaks, and upconversion luminescence over the range of wavelengths from near-infrared to visible. Expl...

  • Review
  • Open Access
24 Citations
4,296 Views
22 Pages

21 July 2021

Proliferative verrucous leukoplakia (PVL) is considered as an oral potentially malignant disorder (OPMD) that presents with a high tendency to recurrence after treatment and has the highest malignant transformation ratio among all OPMD (50%). Evidenc...

  • Article
  • Open Access
13 Citations
2,960 Views
13 Pages

Fetal alcohol spectrum disorder (FASD) is a prevalent neurodevelopmental condition. Despite FASD being recognized as a clinical disorder there is no globally agreed set of diagnostic criteria. Accurate and timely diagnosis of FASD is imperative to in...

  • Review
  • Open Access
176 Citations
34,308 Views
16 Pages

Diagnostic Criteria for Fibromyalgia: Critical Review and Future Perspectives

  • Carmen M. Galvez-Sánchez and
  • Gustavo A. Reyes del Paso

23 April 2020

Fibromyalgia syndrome (FMS) is a chronic illness characterized by widespread pain and other clinical and emotional symptoms. The lack of objective markers of the illness has been a persistent problem in FMS research, clinical management, and social r...

  • Article
  • Open Access
29 Citations
11,020 Views
13 Pages

4 April 2014

Background: Personalized medicine is gradually emerging as a transformative field. Thus far, seven co-developed drug-diagnostic combinations have been approved and several dozen post-hoc drug-diagnostic combinations (diagnostic approved after the dru...

  • Article
  • Open Access
4 Citations
1,871 Views
10 Pages

When Pulmonologists Are Novice to Navigational Bronchoscopy, What Predicts Diagnostic Yield?

  • Louise L. Toennesen,
  • Helene H. Vindum,
  • Ellen Risom,
  • Alexis Pulga,
  • Rafi M. Nessar,
  • Arman Arshad,
  • Alice Christophersen,
  • Yoon Soo Park,
  • Kristoffer Mazanti Cold and
  • Paul Frost Clementsen
  • + 1 author

12 December 2022

Predicting factors of diagnostic yield in electromagnetic navigation bronchoscopy (ENB) have been explored in a number of previous studies based on data from experienced operators. However, little is known about predicting factors when the procedure...

  • Review
  • Open Access
9 Citations
4,176 Views
12 Pages

The Role of Diagnostic Injections in Spinal Disorders: A Narrative Review

  • Brian Y. Kim,
  • Tyler A. Concannon,
  • Luis C. Barboza and
  • Talal W. Khan

9 December 2021

Neck and back pain is increasingly prevalent, and has increased exponentially in recent years. As more resources are dedicated to the diagnosis of pain conditions, it is increasingly important that the diagnostic techniques used are as precise and ac...

  • Review
  • Open Access
1,463 Views
21 Pages

14 October 2025

Due to their unique physicochemical properties, carbon black nanoparticles represent a promising alternative for solving analytical problems. However, diagnostic reagents based on carbon black nanoparticles have not yet found widespread practical app...

  • Feature Paper
  • Review
  • Open Access
26 Citations
12,379 Views
16 Pages

Toward Exosome-Based Neuronal Diagnostic Devices

  • Yong Kyoung Yoo,
  • Junwoo Lee,
  • Hyungsuk Kim,
  • Kyo Seon Hwang,
  • Dae Sung Yoon and
  • Jeong Hoon Lee

29 November 2018

Targeting exosome for liquid biopsy has gained significant attention for its diagnostic and therapeutic potential. For detecting neuronal disease diagnosis such as Alzheimer’s disease (AD), the main technique for identifying AD still relies on positr...

  • Review
  • Open Access
1 Citations
3,368 Views
20 Pages

Artificial Intelligence in Infectious Disease Diagnostic Technologies

  • Chao Dong,
  • Yujing Liu,
  • Jiaqi Nie,
  • Xinhao Zhang,
  • Fei Yu and
  • Yongfei Zhou

15 October 2025

Artificial intelligence (AI), as an emerging interdisciplinary field dedicated to simulating and extending human intelligence, is increasingly integrating into the domain of infectious disease medicine with unprecedented depth and breadth. This narra...

  • Article
  • Open Access
10 Citations
2,035 Views
21 Pages

Enhancing Healthcare for Sarcoma Patients: Lessons from a Diagnostic Pathway Efficiency Analysis

  • Maria Elyes,
  • Philip Heesen,
  • Georg Schelling,
  • Beata Bode-Lesniewska,
  • Gabriela Studer and
  • Bruno Fuchs

9 October 2023

Sarcomas, rare and with lower survival rates than common tumors, offer insights into healthcare efficiency via the analysis of the total interval of the diagnostic pathway, combining the patient interval (time between the first symptom and visit with...

  • Article
  • Open Access
2 Citations
1,835 Views
13 Pages

21 September 2023

Diagnostic classification models (DCMs) are statistical models with discrete latent variables (so-called skills) to analyze multiple binary variables (i.e., items). The one-parameter logistic diagnostic classification model (1PLDCM) is a DCM with one...

  • Review
  • Open Access
2 Citations
2,710 Views
16 Pages

Artificial Intelligence-Augmented Advancements in the Diagnostic Challenges Within Renal Cell Carcinoma

  • Mladen Doykov,
  • Stanislav Valkanov,
  • Usman Khalid,
  • Jasmin Gurung,
  • Gancho Kostov,
  • Bozhidar Hristov,
  • Petar Uchikov,
  • Maria Kraeva,
  • Krasimir Kraev and
  • Stefan Konsulov
  • + 4 authors

26 March 2025

Background: Advancements in artificial intelligence (AI) diagnostics for renal cell carcinoma (RCC) provide valuable information for classification and subtyping, which improve treatment options and patient care. RCC diagnoses are most commonly incid...

  • Article
  • Open Access
2 Citations
3,968 Views
11 Pages

Experience of “One Stop TB Diagnostic Solution” Model in Engaging a Private Laboratory for End-to-End Diagnostic Services in the National TB Elimination Program in Hisar, India

  • Rajesh Raju,
  • Banuru Muralidhara Prasad,
  • Umesh Alavadi,
  • Sanjeev Saini,
  • Mukesh Sabharwal,
  • Akshay Duhan,
  • Sridhar Anand,
  • Manohar Lal,
  • Harpreet Kaur and
  • Rajendra P. Joshi
  • + 5 authors

31 August 2023

The complete diagnostic evaluation of tuberculosis based on its drug-resistance profile is critical for appropriate treatment decisions. The TB diagnostic landscape in India has been transformed with the scaling-up of WHO-recommended diagnostics, but...

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