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17 pages, 7463 KB  
Article
Dynamic Thermal Network Parameter Updating Strategy for IGBT Full-Bridge Modules in Digital Twin Applications
by Jiapeng Shen, Li Zhang, Chuyang Wang, Sibo Sun and Duicheng Zhao
Energies 2026, 19(13), 2999; https://doi.org/10.3390/en19132999 (registering DOI) - 25 Jun 2026
Abstract
To meet the conflicting demands of real-time simulation and high fidelity for thermal modeling of IGBT modules in digital twin applications, this paper presents a dynamic thermal network parameter updating strategy. A hybrid thermal model is constructed by combining a high-fidelity finite-element-method reference [...] Read more.
To meet the conflicting demands of real-time simulation and high fidelity for thermal modeling of IGBT modules in digital twin applications, this paper presents a dynamic thermal network parameter updating strategy. A hybrid thermal model is constructed by combining a high-fidelity finite-element-method reference model with a 3-D compact network. Initial thermal resistance and capacitance parameters are obtained via offline calibration and validated against the transient thermal impedance curve. A dynamic identification method based on recursive least squares with precomputed sensitivity matrices is then proposed. It dynamically updates each independent thermal branch using only real-time chip junction temperature measurements. The Vincotech full-bridge IGBT module is used for simulation validation. The proposed method achieves steady-state identification errors of 3.2% for the IGBT chip thermal resistance and 4.5% for the freewheeling diode chip thermal resistance, outperforming particle swarm optimization and dual Kalman filter in both convergence speed and steady-state accuracy. Thus, it satisfies the requirements of real-time tracking and dynamic evolution for thermal models in digital twin systems. Full article
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11 pages, 1767 KB  
Proceeding Paper
Data-Driven ANN Model Development for Maximum Power Point Estimation in PV Panel Under Partial Shading Conditions
by Mog Akeem Isaacs and Senthil Krishnamurthy
Eng. Proc. 2026, 140(1), 72; https://doi.org/10.3390/engproc2026140072 (registering DOI) - 25 Jun 2026
Abstract
This paper presents a novel approach to designing and implementing an Artificial Neural Network (ANN) for maximum power point tracking (MPPT), trained solely on unshaded photovoltaic (PV) manufacturer datasheets and capable of tracking and predicting the maximum power point (MPP) under changing shading [...] Read more.
This paper presents a novel approach to designing and implementing an Artificial Neural Network (ANN) for maximum power point tracking (MPPT), trained solely on unshaded photovoltaic (PV) manufacturer datasheets and capable of tracking and predicting the maximum power point (MPP) under changing shading conditions. This is also known as partial shading conditions (PSC). PSC arises when shade covers sections of the PV panel due to clouds, trees, dust, or man-made objects such as tall buildings. The proposed ANN-based MPPT technique addresses a common issue faced by conventional MPPT methods under PSC: inaccurate MPPT. PSC induces oscillations on the power-to-voltage curve, resulting in multiple local maxima (LMPPs). However, existing ANN-based MPPT methods are developed and trained on shaded PV datasets. This Neural Network (NN) tracking method complicates the training, development, and implementation processes. It increases the cost of development and requires physical, real-world data collection that requires hardware and a lot of time. All this can be avoided with unshaded PV datasheets. The input parameters used to train the model are temperature (T) and irradiance (G), and the output parameters are maximum power (Pmp) and maximum voltage (Vmp). The ANN-based MPPT technique demonstrated strong performance, accurately predicting the global MPP (GMPP) under PSC with high correlation and low prediction error. Full article
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22 pages, 1501 KB  
Article
Autism Spectrum Disorder Detection Using a Weighted-Average Ensemble of Deep Convolutional Neural Networks on Eye-Tracking Images
by Masroor Ahmed, Sadam Hussain, Ivan Amaya and José Carlos Ortiz-Bayliss
Mach. Learn. Knowl. Extr. 2026, 8(7), 176; https://doi.org/10.3390/make8070176 (registering DOI) - 25 Jun 2026
Abstract
Autism Spectrum Disorder is a long-term neurodevelopmental disorder. Early diagnosis is crucial for timely rehabilitation and intervention. Recently, machine learning and deep learning techniques have been widely explored and have produced encouraging results using eye-tracking scanpath images for the early detection of ASD. [...] Read more.
Autism Spectrum Disorder is a long-term neurodevelopmental disorder. Early diagnosis is crucial for timely rehabilitation and intervention. Recently, machine learning and deep learning techniques have been widely explored and have produced encouraging results using eye-tracking scanpath images for the early detection of ASD. However, these approaches exhibit inconsistent performance and classification error rates, as well as limited generalization, due to differences in learning approaches and architectural designs across individual models. To address these problems, we employed a weighted-average ensemble of deep learning models using eye-tracking scanpath images. In this work, two different pretrained convolutional neural networks were selected, including Xception and VGG16, based on their proven efficacy and performance. Moreover, we fine-tuned each model individually and evaluated them on a dataset containing eye-tracking scanpath images. We implemented a weighted-average ensemble technique to combine the diverse predictions of the two models. It reduces classification errors and improves the model’s generalization and overall performance. The adopted weighted-average ensemble technique achieved an accuracy of 98.18%, with a perfect recall, and a competitive Area Under the Curve (AUC) of 99.59%. These findings highlight that applying a weighted average to integrate multiple models’ predictions strengthens the generalization and reliability of ASD detection. Full article
(This article belongs to the Section Learning)
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23 pages, 6557 KB  
Article
Dynamic Landslide Susceptibility Assessment Under Typhoons with Physics-Guided Optimization: Case Study of Cempaka (2017), Indonesia
by Haoxin Ni and Hongling Tian
Land 2026, 15(7), 1108; https://doi.org/10.3390/land15071108 (registering DOI) - 23 Jun 2026
Abstract
Typhoon-induced landslides in coastal mountainous regions are controlled by the coupled effects of rainfall, wind, topography, and storm-track geometry. However, conventional static susceptibility models have limited ability to represent event-scale forcing under extreme weather conditions. This study develops a physics-guided dynamic landslide susceptibility [...] Read more.
Typhoon-induced landslides in coastal mountainous regions are controlled by the coupled effects of rainfall, wind, topography, and storm-track geometry. However, conventional static susceptibility models have limited ability to represent event-scale forcing under extreme weather conditions. This study develops a physics-guided dynamic landslide susceptibility framework and retrospectively applies it to the 2017 Tropical Cyclone Cempaka event in Pacitan Regency, Indonesia, where 743 landslides were identified. The framework integrates static terrain factors, antecedent wetness, event-scale rainfall accumulation and intensity, maximum wind speed, and a typhoon geometric exposure index derived from IBTrACS best-track information that represents track proximity, topographic shielding, rainfall-favored quadrant effects, and storm-motion effects. Under spatial block cross-validation, model performance improved progressively from the static baseline to the full-factor model, with the receiver operating characteristic area under the curve (ROC-AUC) increasing from 0.648 to 0.751, the precision–recall area under the curve (PR-AUC) reaching 0.826, and the F1-score reaching 0.744. The full-factor model also reduced missed landslide cases from 328 to 205 and concentrated predicted high-susceptibility zones along the typhoon exposure corridor. Additional parameter-sensitivity analyses further indicate that the event-based Egeo setting produced positive performance increments under the event-consistent quadrant convention. These results indicate that physically meaningful typhoon-exposure information can improve the spatial discrimination and interpretability of event-scale landslide susceptibility assessment. Full article
(This article belongs to the Section Land Use, Impact Assessment and Sustainability)
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17 pages, 8857 KB  
Article
An Interpretable Deep Learning System for Fine-Grained Classification and Longitudinal Tracking of Neonatal Auricular Deformities
by Yihui Feng, Xujun Hu, Xiwen Zhang, Xiaobao Ma, Jialin Xie, Jianyong Chen and Yangyang Yuan
Biology 2026, 15(13), 985; https://doi.org/10.3390/biology15130985 (registering DOI) - 23 Jun 2026
Abstract
Early non-invasive correction of neonatal auricular deformities is highly dependent on timely and precise diagnosis. However, clinical practice is often compromised by the subjectivity of visual assessments and the lack of objective tracking metrics, which frequently leads to missed optimal treatment windows. To [...] Read more.
Early non-invasive correction of neonatal auricular deformities is highly dependent on timely and precise diagnosis. However, clinical practice is often compromised by the subjectivity of visual assessments and the lack of objective tracking metrics, which frequently leads to missed optimal treatment windows. To address these challenges, we developed an interpretable deep learning-based diagnostic system for the automated screening and fine-grained classification of these deformities. Methodologically, a large-scale, multi-source dataset (n = 4644) was curated to support model training. The system pairs an automated object detector (YOLOv11) for background-reduced region-of-interest isolation with a cascaded classification pipeline optimized via ConvNeXt-Tiny. Crucially, we introduced a supervised contrastive learning module to project high-dimensional morphological features into a continuous severity score, enabling quantitative longitudinal tracking of therapeutic efficacy. To evaluate generalization and robustness, the framework underwent rigorous evaluation across three independent real-world cohorts and one controlled synthetic stress test. The system achieved 88.2% accuracy (Area Under the Curve (AUC): 0.949) in binary screening and 87.4% accuracy (macro-AUC: 0.976) in multi-class subtyping on the internal baseline. To enhance interpretability and build clinical trust, Gradient-weighted Class Activation Mapping (Grad-CAM) was utilized to explore the spatial distribution of the model’s attention, which frequently aligned with key anatomical landmarks. Furthermore, the learned severity scores robustly quantified post-intervention improvements (p = 0.0004), effectively capturing subtle anatomical normalization. While validation for rare subtypes remains underpowered, and the severity score currently functions mainly as a learned morphological similarity index requiring future clinical calibration, this study ultimately provides an objective and standardized web-based tool to facilitate the early intervention and precision management of neonatal auricular anomalies. Full article
(This article belongs to the Special Issue AI Deep Learning Approach to Study Biological Questions (3rd Edition))
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11 pages, 361 KB  
Article
Association of Serial Lactate-to-Albumin and C-Reactive Protein-to-Albumin Ratios with In-Hospital Mortality After Out-of-Hospital Cardiac Arrest
by Wan Young Heo, Dong Hun Lee, Seok Jin Ryu, Byung Kook Lee, Yong Hun Jung and Kyung Woon Jeung
J. Clin. Med. 2026, 15(13), 4851; https://doi.org/10.3390/jcm15134851 (registering DOI) - 23 Jun 2026
Viewed by 47
Abstract
Background: The lactate-to-albumin ratio (LAR) and C-reactive protein-to-albumin ratio (CAR) are biomarkers for metabolic stress and inflammation. However, their prognostic significance after return of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) remains unclear. Therefore, this study aims to investigate the association [...] Read more.
Background: The lactate-to-albumin ratio (LAR) and C-reactive protein-to-albumin ratio (CAR) are biomarkers for metabolic stress and inflammation. However, their prognostic significance after return of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) remains unclear. Therefore, this study aims to investigate the association between serial LAR/CAR measurements and in-hospital mortality. Methods: This retrospective observational cohort study included adult comatose patients with OHCA treated with targeted temperature management between January 2022 and December 2025. Serum lactate, albumin, and C-reactive protein levels were measured at admission and at 24, 48, and 72 h after ROSC. The primary outcome was in-hospital mortality. Multivariable logistic regression analyses were performed to assess independent associations of LAR and CAR with in-hospital mortality, and discriminatory performance was assessed using the area under the receiver operating characteristic curve (AUC). Results: Of the 284 eligible patients, 253 were included in the final analysis. Of these, 80 patients died in hospital, corresponding to an in-hospital mortality rate of 31.6%. LAR and CAR were significantly higher in non-survivors than in survivors at admission and at 24, 48, and 72 h after ROSC. After adjustment for potential confounders, LAR was associated with in-hospital mortality at all assessed time points. CAR was independently associated with in-hospital mortality at admission and at 48 and 72 h after ROSC, but not at 24 h. The AUCs of LAR for predicting in-hospital mortality ranged from 0.702 to 0.734, whereas those of CAR ranged from 0.640 to 0.690. Conclusions: In this single-center retrospective cohort of post-ROSC OHCA patients, sequential tracking of LAR and CAR profiles during the first 72 h after ROSC provided meaningful insights into in-hospital mortality. LAR showed a more consistent independent association with mortality and fair discriminatory performance, whereas CAR demonstrated limited prognostic value despite its association with mortality. Full article
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19 pages, 15698 KB  
Article
High-Precision Identification of Surface Freshwater on Bedrock Islands Based on Optical and SAR Imagery
by Qian Cheng, Haoli Xu, Zijian Cheng, Zhao Lu, Yong Huang, Qizhan Chen, Fangyuan Wang and Daqing Wang
Environments 2026, 13(6), 358; https://doi.org/10.3390/environments13060358 (registering DOI) - 22 Jun 2026
Viewed by 85
Abstract
Accurately mapping surface freshwater bodies (e.g., ponds, reservoirs, and small lakes) is vital for managing insular ecosystems and communities. However, satellite-based extraction in coastal settings is challenged by seawater intrusion, complex topography, and cloud cover. Focusing on bedrock islands outside China’s Pearl River [...] Read more.
Accurately mapping surface freshwater bodies (e.g., ponds, reservoirs, and small lakes) is vital for managing insular ecosystems and communities. However, satellite-based extraction in coastal settings is challenged by seawater intrusion, complex topography, and cloud cover. Focusing on bedrock islands outside China’s Pearl River Estuary, this study developed a robust method to address these issues. We used both Gaofen-1 (GF-1) optical and Gaofen-3 (GF-3) Synthetic Aperture Radar (SAR) imagery, supported by field-collected water quality samples from surface freshwater body shorelines for model training and validation. The performance of two index-based methods (the Normalized Difference Water Index, NDWI, and the Normalized Difference Vegetation Index, NDVI), two machine learning algorithms (Random Forest, RF, and Support Vector Machine, SVM), and a U-Net convolutional neural network (U-Net) deep learning model was compared. The U-Net model achieved the highest accuracy, with Area Under the Curve (AUC) values of 0.881 (GF-1) and 0.840 (GF-3). It effectively discriminated freshwater from seawater and mitigated cloud interference, demonstrating superior precision and robustness over traditional methods. This work establishes a high-precision framework for monitoring island freshwater resources, supporting sustainable water management. The proposed framework provides a practical tool for tracking freshwater availability under climate variability and anthropogenic pressures, contributing to the monitoring of Sustainable Development Goal (SDG) indicator 6.3.2 on ambient water quality. Full article
(This article belongs to the Special Issue Remote Sensing Innovations for Water Resources Assessment)
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26 pages, 4265 KB  
Article
An Integrated Improved Artificial Potential Field and GA-LQR/PID Control Framework for Autonomous Vehicle Lane-Change Overtaking in Structured Roads
by Yue Huang, Zhiwei Guan and Yu Zhao
World Electr. Veh. J. 2026, 17(6), 324; https://doi.org/10.3390/wevj17060324 (registering DOI) - 22 Jun 2026
Viewed by 140
Abstract
Lane-changing and overtaking constitute a typical complex driving manoeuvre for intelligent vehicles operating on structured roads; this task demands that the vehicle not only plan a safe and smooth lane-change trajectory but also requires the control system to maintain high tracking accuracy and [...] Read more.
Lane-changing and overtaking constitute a typical complex driving manoeuvre for intelligent vehicles operating on structured roads; this task demands that the vehicle not only plan a safe and smooth lane-change trajectory but also requires the control system to maintain high tracking accuracy and lateral stability. Addressing the challenges of real-time path planning and stable tracking control inherent in lane-changing and overtaking scenarios, this paper proposes a trajectory planning and control method that integrates an improved artificial potential field (APF) approach with a lateral–longitudinal cooperative controller. Regarding path planning, the proposed method constructs attractive and repulsive fields based on the APF framework, while introducing virtual target points, elliptical obstacle models, and velocity-dependent repulsive fields to mitigate the risk of local minima and enhance dynamic obstacle avoidance capabilities. To ensure trajectory continuity and trackability, a fifth-order polynomial is employed to smooth the planned path. Regarding control, the method utilises a Linear Quadratic Regulator (LQR)—optimised via a genetic algorithm—for lateral control; this is coupled with a dual-PID longitudinal controller that generates throttle and braking commands based on vehicle speed errors, thereby establishing a cooperative lateral–longitudinal tracking control strategy. The proposed method is validated using a CarSim–MATLAB/Simulink co-simulation platform. Simulation results demonstrate that the proposed method significantly improves trajectory-tracking accuracy and vehicle stability during lane-changing and overtaking manoeuvres. In a single lane-change scenario, the maximum lateral error is reduced from approximately 0.62 m to 0.22 m, and the heading angle error decreases from about 0.058 rad to 0.01 rad; in a continuous lane-changing scenario, the maximum lateral error drops from approximately 0.30 m to 0.04 m, while the heading angle error falls from about 0.016 rad to 0.005 rad. Furthermore, the yaw rate, sideslip angle, and lateral acceleration are reduced by 39.1%, 22.2%, and 28.9%, respectively. These results confirm that, under the specified simulation conditions, the proposed method exhibits superior tracking performance and stability. Future research could further explore more complex driving scenarios, such as curved roads, multi-vehicle interactions, sensor uncertainties, actuator delays, and real-vehicle field experiments. Full article
(This article belongs to the Section Automated and Connected Vehicles)
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24 pages, 2553 KB  
Article
Multi-UAV Cooperative Hunting in Obstructed Environments via a Multi-Agent Proximal Policy Optimization with Curriculum Learning
by Longjie Zheng, Junlin Zhou, Haijun Peng, Bai Li and Xinwei Wang
Sensors 2026, 26(12), 3907; https://doi.org/10.3390/s26123907 - 19 Jun 2026
Viewed by 185
Abstract
With the increasing complexity of unmanned aerial vehicle (UAV) missions in complex obstacle environments, cooperative hunting of maneuvering ground targets by UAV swarms has become an important problem for multi-agent autonomous decision-making. This paper focuses on a simulated three-UAV hunting scenario in a [...] Read more.
With the increasing complexity of unmanned aerial vehicle (UAV) missions in complex obstacle environments, cooperative hunting of maneuvering ground targets by UAV swarms has become an important problem for multi-agent autonomous decision-making. This paper focuses on a simulated three-UAV hunting scenario in a two-dimensional obstructed environment, where UAVs must search for, approach, encircle, and continuously track a target while avoiding static obstacles under local observation. To address the problem of multi-UAV cooperative hunting of dynamic targets in complex obstacle environments, this paper proposes a curriculum learning (CL)-based Multi-Agent Proximal Policy Optimization algorithm, termed CL-MAPPO. Specifically, a three-stage progressive training curriculum is designed to overcome the challenges of low exploration efficiency, slow environmental adaptation, and difficult convergence of cooperative hunting policies faced by multi-agent deep reinforcement learning in hunting tasks, thereby gradually enhancing the cooperative hunting capability of UAVs in complex environments. Curriculum I employs fixed obstacles and a stationary target position to train the UAVs’ basic obstacle avoidance and target search abilities. Curriculum II introduces randomly generated obstacles and target positions to improve the UAVs’ adaptability to varying environments. Curriculum III further incorporates a dynamic target, prompting the UAVs to learn effective hunting strategies against maneuvering targets. The simulation experiment includes ablation experiments against MAPPO without curriculum learning and comparative simulations against MADDPG and MADQN, using reward convergence curves and trajectory visualizations to evaluate the training results. The results show that, under the same training episodes in the ablation experiment, CL-MAPPO reaches a higher and more stable reward level than vanilla MAPPO, indicating improved learning efficiency without increasing model complexity. In the comparative experiment, the CL-MAPPO algorithm achieved a higher success rate in cooperative hunting. These simulation experiments verify the effectiveness and superiority of the CL-MAPPO algorithm in multi-agent cooperative hunting tasks. Full article
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20 pages, 5294 KB  
Article
Mechanical and Microstructural Behavior of Fiber–Nanomaterial Composite-Modified Recycled Sand Infill for Soil Stabilization
by Xinyi Du, Xun Han, Haibo Kang, Xudong Wang, Wei Wang, Chen Zhang and Hang Zhou
Buildings 2026, 16(12), 2347; https://doi.org/10.3390/buildings16122347 - 11 Jun 2026
Viewed by 242
Abstract
This study addresses the early-age brittleness and performance limitations of sustainable cement soil. While prior works optimized the baseline compressive strength using recycled sand and nanoclay, the multi-scale synergistic effects of fibers and nanomaterials on the post-peak deformation remain underexplored. To address this [...] Read more.
This study addresses the early-age brittleness and performance limitations of sustainable cement soil. While prior works optimized the baseline compressive strength using recycled sand and nanoclay, the multi-scale synergistic effects of fibers and nanomaterials on the post-peak deformation remain underexplored. To address this gap, a composite modification system incorporating recycled sand, nanoclay, polypropylene fibers, and graphene derivatives was developed. The experimental program comprised standard specimen fabrication, early-age curing, and unconfined compressive strength (UCS) testing, supplemented by RBF neural network curve fitting and quantitative ArcGIS digital image processing of scanning electron microscopy (SEM) micrographs. The results demonstrate that optimizing the fiber parameters (0.6% content with 6 mm length) successfully increases the early UCS to 2263.2 kPa, which is further elevated to a peak of 2755.0 kPa upon co-incorporation with 0.05% small-sized graphene oxide. Correspondingly, a newly introduced ductility index quantitatively confirms that the single-fiber reinforcement yields an index of 1.93, which is further enhanced to 2.02 by the graphene composite system. Microstructure tracking and digital image extraction revealed that the SEM-derived surface porosity decreased significantly, exhibiting a clear inverse relationship with the macroscopic mechanical strength. These quantitative microstructural shifts confirm that graphene effectively filled micropores and reinforced the fiber–matrix interface, establishing a dense matrix network with enhanced interfacial bonding. This multi-scale approach offers a sustainable strategy for green geotechnical applications. Full article
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24 pages, 8339 KB  
Article
Assessment of Future Typhoon Rainfall and Equivalent Rainfall Return Periods Based on the WRF-PGW Method
by Haixin Li, Mingfeng Huang, Yanbo Wang, Kang Cai, Baodong Liu, Huajie Xiao and Yi Zhou
Appl. Sci. 2026, 16(12), 5914; https://doi.org/10.3390/app16125914 - 11 Jun 2026
Viewed by 102
Abstract
Landfalling typhoons are the dominant trigger of short-duration extreme rainfall along the Zhejiang coast. It is necessary to estimate the recurrence of future typhoon rainfall at the city scale under the global-warming scenarios. Using Super Typhoon Lekima (2019) as a representative high-impact event, [...] Read more.
Landfalling typhoons are the dominant trigger of short-duration extreme rainfall along the Zhejiang coast. It is necessary to estimate the recurrence of future typhoon rainfall at the city scale under the global-warming scenarios. Using Super Typhoon Lekima (2019) as a representative high-impact event, this study develops an event-based assessment framework for Taizhou city by combining the Weather Research and Forecast (WRF) model simulation, pseudo-global-warming (PGW) perturbation experiments, and generalized extreme value analysis. The historical simulation is first evaluated against the China Meteorological Administration best track, storm intensity evolution, and station rainfall observations. Future counterparts of the same event are then generated using CMIP6-derived thermodynamic perturbations under SSP1-2.6, SSP2-4.5, SSP3-7.0, and SSP5-8.5. Finally, scenario-dependent rainfall totals are projected onto a historical GEV curve to identify equivalent historical rainfall return periods. Results show that the WRF setup reproduces the main track, intensity tendency, and rainfall timing of Lekima with reasonable fidelity. The ensemble-mean cumulative rainfall over the Taizhou area increases from 204.75 mm in the historical simulation to 335.85, 366.72, 400.79, and 464.08 mm under the four SSPs, respectively. These increases translate into equivalent historical rainfall return periods of 47.40, 84.61, 164.28, and 604.05 years, compared with 5.24 years for the historical case. The results indicate that the moderate thermodynamic rainfall amplification produces a highly nonlinear escalation of event rarity based on historical frequency statistics. This implies that future typhoon rainfall should be interpreted using scenario-aware benchmarks within the historical reference framework. Full article
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23 pages, 6567 KB  
Article
Reinforcement Learning-Enhanced Adaptive NMPC for Safe Autonomous Driving
by Sheng Jin and Joel Yi Yang Loh
Electronics 2026, 15(12), 2577; https://doi.org/10.3390/electronics15122577 - 11 Jun 2026
Viewed by 206
Abstract
Nonlinear Model Predictive Control (NMPC) has garnered significant attention in autonomous systems due to its ability to predict future states and manage complex vehicle dynamics. However, the adaptability of existing NMPC methods is constrained by having to manually set the weight coefficients in [...] Read more.
Nonlinear Model Predictive Control (NMPC) has garnered significant attention in autonomous systems due to its ability to predict future states and manage complex vehicle dynamics. However, the adaptability of existing NMPC methods is constrained by having to manually set the weight coefficients in the NMPC cost function. This study aims to explore a novel approach that integrates NMPC with Reinforcement Learning (RL), specifically employing Proximal Policy Optimization (PPO), to dynamically adjust NMPC weight matrices. The investigation begins by establishing a physics-based model for a two wheeled differential drive vehicle. A PPO model is then trained and deployed in real time to adapt to the NMPC weight matrices, achieving a 71% reduction in tracking error compared with the NMPC baseline. Importantly, the performance gain arises from PPO’s ability to reshape the NMPC cost function in real time, amplifying both orientation and lateral penalties in curves while relaxing them on straights, thereby enabling adaptive trade-offs between accuracy and control effort that static-weight NMPC cannot achieve. To enhance safety, the controller is integrated with a Control Barrier Function (CBF) layer for real-time obstacle avoidance, while PPO’s real-time weight adaptation contributes to improved tracking performance relative to NMPC+CBF. Finally, robustness evaluations under friction uncertainty, sensor noise, and path disturbances demonstrate that the PPO+NMPC+CBF method maintains reliable tracking accuracy and safety margins. Full article
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14 pages, 1226 KB  
Article
Circulating Novel Adipokines in Critically Ill Patients with and Without Sepsis
by Vassiliki Giannopoulou, Ioannis Ilias, Chrysi Keskinidou, Charikleia S. Vrettou, Olga Kampouropoulou, Nikolaos S. Lotsios, Matina Kardara, Kostas A. Papavassiliou, Georgios-Ioannis Poupouzas, Vasileios Issaris, Anastasia Kotanidou, Alice G. Vassiliou and Ioanna Dimopoulou
Biomedicines 2026, 14(6), 1324; https://doi.org/10.3390/biomedicines14061324 - 11 Jun 2026
Viewed by 202
Abstract
Background/Objectives: Adipokines are candidate biomarkers in critical illness due to their roles in immunity and metabolism, both profoundly altered in sepsis. Omentin-1, vaspin, and chemerin have been studied in selected septic cohorts, but not concurrently in a heterogeneous ICU population including both [...] Read more.
Background/Objectives: Adipokines are candidate biomarkers in critical illness due to their roles in immunity and metabolism, both profoundly altered in sepsis. Omentin-1, vaspin, and chemerin have been studied in selected septic cohorts, but not concurrently in a heterogeneous ICU population including both septic and non-septic patients. Methods: Prospective observational cohort of 200 consecutive ICU patients with 28-day follow-up. Biomarkers were measured by ELISA within 24 h of admission. Analyses included Mann–Whitney U tests, Spearman correlations, ROC curves, and logistic regression with APACHE II and SOFA as comparators. Results: Vaspin was significantly higher in septic versus non-septic patients (406.4 [190.0–799.6] vs. 275.8 [101.8–559.8] pg/mL; p = 0.009). Omentin-1 was elevated in 28-day non-survivors (34.4 [22.5–56.1] vs. 25.1 [15.0–48.4] ng/mL; p = 0.037; AUROC 0.599), but lost significance after APACHE II adjustment (p = 0.295). Chemerin trended lower in non-survivors (p = 0.099); in septic patients, it correlated inversely with SOFA (r = −0.43) and lactate (r = −0.40), both p < 0.001. IL-6 and IL-10 were higher in non-survivors; IL-10 predicted 28-day mortality (AUROC 0.783), comparable to APACHE II (0.785). Conclusions: Vaspin distinguishes sepsis in mixed ICU populations. Omentin-1 shows a severity-driven association with mortality that does not survive APACHE II adjustment (AUROC 0.599, poor standalone discrimination), while chemerin inversely tracks hypoperfusion markers in septic patients, suggesting a potential counter-regulatory role requiring mechanistic confirmation. Individually, these adipokines do not add prognostic value beyond established severity scores, but their biological orthogonality to classical cytokines warrants exploration in multi-marker panel studies. Full article
(This article belongs to the Special Issue Recent Advances in Adipokines (3nd Edition))
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22 pages, 3675 KB  
Article
Dynamic Response of Track-Mounted Advanced Support Equipment Under Different Working Conditions
by Zhen Tian, Shan Gao, Yongkang Li, Long Zheng, Caifeng Zhang, Guang Yang and Zhihao Liu
Processes 2026, 14(12), 1874; https://doi.org/10.3390/pr14121874 - 9 Jun 2026
Viewed by 204
Abstract
Roof instability in the heading area of fully mechanized excavation roadways, together with insufficient coordinated operation between excavation and support, severely restricts tunneling safety and construction efficiency. A novel track-mounted advanced support equipment structure with an articulated curved roof beam is proposed in [...] Read more.
Roof instability in the heading area of fully mechanized excavation roadways, together with insufficient coordinated operation between excavation and support, severely restricts tunneling safety and construction efficiency. A novel track-mounted advanced support equipment structure with an articulated curved roof beam is proposed in this study. Considering actual underground working conditions, including uneven roof contact, eccentric loading and local support failure, a three-degree-of-freedom dynamic model covering vertical, pitch and roll motions is established based on Lagrange’s equations. Dynamic characteristics under varying load amplitudes, excitation frequencies, static load offsets and typical support failure modes are systematically analyzed. The results reveal that only vertical vibration emerges under the full support condition, and the resonance frequency of the system is approximately 10 Hz. The maximum steady-state vertical displacement reaches 0.6406 mm with an RMS of 0.5472 mm under an intact support state. The pitch vibration amplitude caused by the failure of the first support group is three times that of the second group, proving front supports dominate anti-overturning capacity. Side beam failure triggers remarkable roll-coupled vibration, while middle beam failure mainly enlarges vertical displacement. This paper clarifies the vertical–pitch–roll coupling vibration mechanism induced by local support failure. Parameter sensitivity analysis reveals that static load offset has the highest sensitivity, while excitation frequency (within 4–6 Hz) and damping ratio exhibit negligible influence on the steady-state response. The obtained quantitative results can provide a reliable theoretical reference for structural optimization, stability regulation and safety monitoring of track-mounted advanced support facilities. Full article
(This article belongs to the Section Petroleum and Low-Carbon Energy Process Engineering)
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10 pages, 3663 KB  
Article
Study of the Effects of Radiation Exposure on the Parameters of Selected Silicon Photomultipliers
by Ian G. Bearden, Valentin Buchakchiev, Daniel Ivanov, Mira Gencheva, Venelin Kozhuharov and Yury A. Melikyan
Signals 2026, 7(3), 49; https://doi.org/10.3390/signals7030049 - 29 May 2026
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Abstract
Silicon photomultipliers (SiPMs) have become widely used as photodetectors in high-energy physics, nuclear physics, medical imaging, and space applications. In many of these fields, SiPMs are required to operate in high-radiation environments, which are notoriously problematic for silicon sensors. For this reason, it [...] Read more.
Silicon photomultipliers (SiPMs) have become widely used as photodetectors in high-energy physics, nuclear physics, medical imaging, and space applications. In many of these fields, SiPMs are required to operate in high-radiation environments, which are notoriously problematic for silicon sensors. For this reason, it is essential to study the changes in their performance characteristics after exposure to radiation. In this study, a number of SiPM samples were exposed to non-uniform radiation at the CHARM facility at CERN. Half of the samples were operated above breakdown during the test, while others remained off. Intermittent measurements allowed for tracking the changes in I-V curves and signal shapes during the irradiation itself. The focus was on detecting differences in irradiation damage between the operational and non-operational SiPM samples. The I-V curves and signal shapes in both cases for three different types of SiPM are presented, and a comparison is made. Full article
(This article belongs to the Special Issue Ionizing Radiation Signal Propagation, Measurement, and Simulation)
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