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Search Results (2,474)

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19 pages, 1190 KB  
Article
Integrating Multi-Strategy Improvements to Sand Cat Group Optimization and Gradient-Boosting Trees for Accurate Prediction of Microclimate in Solar Greenhouses
by Xiao Cui, Yuwei Cheng, Zhimin Zhang, Juanjuan Mu and Wuping Zhang
Agriculture 2025, 15(17), 1849; https://doi.org/10.3390/agriculture15171849 - 29 Aug 2025
Abstract
Solar greenhouses are an important component of modern facility agriculture, and the dynamic changes in their internal environment directly affect crop growth and yield. Among these factors, crop transpiration releases water vapor through transpiration, directly altering the indoor humidity balance and forming a [...] Read more.
Solar greenhouses are an important component of modern facility agriculture, and the dynamic changes in their internal environment directly affect crop growth and yield. Among these factors, crop transpiration releases water vapor through transpiration, directly altering the indoor humidity balance and forming a dynamic coupling with factors such as temperature and light. The environment of solar greenhouses exhibits highly nonlinear and multivariate coupling characteristics, leading to insufficient prediction accuracy in existing models. However, accurate predictions are crucial for regulating crop growth and yield. However, current mainstream greenhouse environmental prediction models still have obvious limitations when dealing with such complexity: traditional machine learning models and single-variable-driven models have issues such as insufficient accuracy (average MAE is 15–20% higher than in this study) and weak adaptability to nonlinear environmental changes in multi-environmental factor coupling predictions, making it difficult to meet the needs of precision farming. A review of relevant research over the past five years shows that while LSTM-based models perform well in time series prediction, they ignore the spatial correlations between environmental factors. Models incorporating attention mechanisms can capture key variables but suffer from high computational costs. To address these issues, this study proposes a prediction model based on multi-strategy optimization and gradient-boosting (GBDT) algorithms. By introducing a multi-scale feature fusion module, it addresses the accuracy issues in multi-factor coupling prediction. Additionally, it employs a lightweight network design to balance prediction performance and computational efficiency, filling the gap in existing research applications under complex greenhouse environments. The model optimizes data preprocessing and model parameters through Sobol sequence initialization, adaptive t-distribution perturbation strategies, and Gaussian–Cauchy mixture mutation strategies and combines CatBoost for modeling to enhance prediction accuracy. Experimental results show that the MSCSO–CatBoost model performs excellently in temperature prediction, with the mean absolute error (MAE) and root mean square error (RMSE) reduced by 22.5% (2.34 °C) and 24.4% (3.12 °C), respectively, and the coefficient of determination (R2) improved to 0.91, significantly outperforming traditional regression methods and combinations of other optimization algorithms. Additionally, the model demonstrates good generalization capability in predicting multiple environmental variables such as temperature, humidity, and light intensity, adapting to environmental fluctuations under different climatic conditions. This study confirms that combining multi-strategy optimization with gradient-boosting algorithms can significantly improve the prediction accuracy of solar greenhouse environments, providing reliable support for precision agricultural management. Future research could further explore the model’s adaptive optimization in complex climatic regions. Full article
(This article belongs to the Section Artificial Intelligence and Digital Agriculture)
18 pages, 2636 KB  
Article
Urine Metabolomics of Gout Reveals the Dynamic Reprogramming and Non-Invasive Biomarkers of Disease Progression
by Guizhen Zhu, Yuan Luo, Nan Su, Xiangyi Zheng, Zhusong Mei, Qiao Ye, Jie Peng, Peiyu An, Yangqian Song, Weina Luo, Hongxia Li, Guangyun Wang and Haitao Zhang
Metabolites 2025, 15(9), 580; https://doi.org/10.3390/metabo15090580 - 29 Aug 2025
Abstract
Background/Objectives: Gout, a complex metabolic disorder of increasing global incidence, remains incompletely understood in its pathogenesis. Current diagnostic approaches exhibit significant limitations, including insufficient specificity and the requirement for invasive joint aspiration, highlighting the need for non-invasive, sensitive biomarkers for early detection. Methods: [...] Read more.
Background/Objectives: Gout, a complex metabolic disorder of increasing global incidence, remains incompletely understood in its pathogenesis. Current diagnostic approaches exhibit significant limitations, including insufficient specificity and the requirement for invasive joint aspiration, highlighting the need for non-invasive, sensitive biomarkers for early detection. Methods: Urine metabolites were extracted from 28 healthy controls, 13 asymptomatic hyperuricemia (HUA) patients, and 29 acute gouty arthritis (AGA) patients. The extracted metabolites were analyzed by UHPLC-MS/MS for untargeted metabolomics. Differential metabolites were screened by partial least squares discriminant analysis (PLS-DA) and volcano plot analysis. Pathway analysis determined the core disorder pathway of gout progression. Results: A total of 278 differential metabolites associated with gout progression were identified. The most pronounced metabolic alterations were observed between the AGA and control groups, indicative of substantial metabolic reprogramming during disease transition. Metabolic pathway analysis revealed four significantly dysregulated pathways: histidine metabolism, nicotinate and nicotinamide metabolism, phenylalanine metabolism, and tyrosine metabolism. Receiver operating characteristic (ROC) curve analysis revealed that three urine markers with high diagnostic efficacy—oxoamide, 3-methylindole, and palmitic acid—exhibited progressive alterations across the disease continuum. Conclusions: This metabolomics study identified core regulatory metabolites and newly discovered metabolic pathways underlying gout pathogenesis, along with novel urinary biomarkers capable of predicting HUA-to-AGA progression. The aberrant levels of key metabolites in the disordered pathway implicate neuroimmune dysregulation, energy metabolism disruption, and oxidative stress in gout pathogenesis. These findings provide new foundations and strategies for the daily monitoring and prevention of gout. Full article
15 pages, 1127 KB  
Article
Real-Time Gas Emission Modeling for the Heading Face of Roadway in Single and Medium-Thickness Coal Seam
by Peng Yang, Xuanping Gong, Hongwei Jin and Xingying Ma
Energies 2025, 18(17), 4592; https://doi.org/10.3390/en18174592 - 29 Aug 2025
Abstract
The behavior of gas emissions at the heading face of the coal mine is a key indicator of potentially harmful gas disaster risk, necessitating in-depth study via analytical and statistical methods. However, conventional prediction and evaluation methods depend on long-interval statistical data, which [...] Read more.
The behavior of gas emissions at the heading face of the coal mine is a key indicator of potentially harmful gas disaster risk, necessitating in-depth study via analytical and statistical methods. However, conventional prediction and evaluation methods depend on long-interval statistical data, which are too coarse for and lack the immediacy required for real-time applications. Based on the physical laws of gas storage and flow, a refined computational model has been developed to compute dynamic gas emission rates that vary with geology and excavating process. Furthermore, by comparing the computed outputs with actual monitoring data, it becomes possible to assess whether abnormal gas emissions are occurring. Methodologically, this model first applies the finite difference method to compute the dynamic gas flux and the dynamic residual gas content. It then determines the exposure duration of each segment of the roadway wall at any given moment, as well as the mass of newly dislodged coal. The total gas emission rate at a specific sensor location is obtained by aggregating the contributions from all of the exposed wall and the freshly dislodged coal. Owing to some simplifications, the model’s applicability is currently restricted to single, medium-thick coal seams. The model was preliminarily implemented in Python(3.13.2) and validated against a case study of an active heading face. The results demonstrate a strong concordance between model predictions and field measurements. The model notably captures the significant variance in emission rates resulting from different mining activities, the characteristic emission surges from dislodged coal and newly exposed coal walls, and the influence of sensor placement on monitoring outcomes. Full article
(This article belongs to the Topic Advances in Coal Mine Disaster Prevention Technology)
17 pages, 1405 KB  
Article
Projecting Range Shifts of Hippophae neurocarpa in China Under Future Climate Change Using CMIP6 Models
by Bing Zhu, Yaqin Peng and Danping Xu
Diversity 2025, 17(9), 609; https://doi.org/10.3390/d17090609 - 28 Aug 2025
Abstract
Hippophae neurocarpa S. W. Liu & T. N. Ho exhibits established medicinal characteristics, valuable dietary attributes, and remarkable adaptability, displaying strong resistance to cold, drought, and to acidic and alkaline soils. These traits and others make it a valuable species for soil erosion [...] Read more.
Hippophae neurocarpa S. W. Liu & T. N. Ho exhibits established medicinal characteristics, valuable dietary attributes, and remarkable adaptability, displaying strong resistance to cold, drought, and to acidic and alkaline soils. These traits and others make it a valuable species for soil erosion control and a distinctive economic forest tree in western China. However, research on its geographic distribution remains limited. To address this gap, we employed the MaxEnt model to map its current distribution and to predict the future geographic distribution of suitable habitats for this species under SSP1-2.6, SSP2-4.5, and SSP5-8.5 climate scenarios. Collectively, these data suggest that the species’ current and future suitable habitats are predominantly concentrated at the junction of the northeastern Qinghai-Tibet Plateau and the Loess Plateau. Under present climatic conditions, highly suitable habitats are primarily located in the northeastern Qinghai-Tibet Plateau, with smaller patches in the Hengduan and Himalaya mountains. The AUC value of this model reached 0.954; projections under three future emission scenarios indicate an overall expansion trend in suitable habitat area. Notably, by the 2070s under the SSP2-4.5 scenario, the total suitable habitat area is projected to increase by 11.64%—the highest among all scenarios. Additionally, climate change is expected to drive a slight northward shift in the species’ distribution center toward higher latitudes. Key environmental factors influencing its projected distribution include elevation (elev), temperature seasonality (bio04), mean temperature of the coldest quarter (bio11), and precipitation of the warmest quarter (bio18). These insights are critical for conserving H. neurocarpa’s genetic resources and guiding future biodiversity conservation strategies. Full article
(This article belongs to the Topic Responses of Trees and Forests to Climate Change)
24 pages, 4427 KB  
Article
Three-Dimensional Convolutional Neural Networks (3D-CNN) in the Classification of Varieties and Quality Assessment of Soybean Seeds (Glycine max L. Merrill)
by Piotr Rybacki, Kiril Bahcevandziev, Diego Jarquin, Ireneusz Kowalik, Andrzej Osuch, Ewa Osuch and Janetta Niemann
Agronomy 2025, 15(9), 2074; https://doi.org/10.3390/agronomy15092074 - 28 Aug 2025
Abstract
The precise identification, classification, sorting, and rapid and accurate quality assessment of soybean seeds are extremely important in terms of the continuity of agricultural production, varietal purity, seed processing, protein extraction, and food safety. Currently, commonly used methods for the identification and quality [...] Read more.
The precise identification, classification, sorting, and rapid and accurate quality assessment of soybean seeds are extremely important in terms of the continuity of agricultural production, varietal purity, seed processing, protein extraction, and food safety. Currently, commonly used methods for the identification and quality assessment of soybean seeds include morphological analysis, chemical analysis, protein electrophoresis, liquid chromatography, spectral analysis, and image analysis. The use of image analysis and artificial intelligence is the aim of the presented research, in which a method for the automatic classification of soybean varieties, the assessment of the degree of damage, and the identification of geometric features of soybean seeds based on numerical models obtained using a 3D scanner has been proposed. Unlike traditional two-dimensional images, which only represent height and width, 3D imaging adds a third dimension, allowing for a more realistic representation of the shape of the seeds. The research was conducted on soybean seeds with a moisture content of 13%, and the seeds were stored in a room with a temperature of 20–23 °C and air humidity of 60%. Individual soybean seeds were scanned to create 3D models, allowing for the measurement of their geometric parameters, assessment of texture, evaluation of damage, and identification of characteristic varietal features. The developed 3D-CNN network model comprised an architecture consisting of an input layer, three hidden layers, and one output layer with a single neuron. The aim of the conducted research is to design a new, three-dimensional 3D-CNN architecture, the main task of which is the classification of soybean seeds. For the purposes of network analysis and testing, 22 input criteria were defined, with a hierarchy of their importance. The training, testing, and validation database of the SB3D-NET network consisted of 3D models obtained as a result of scanning individual soybean seeds, 100 for each variety. The accuracy of the training process of the proposed SB3D-NET model for the qualitative classification of 3D models of soybean seeds, based on the adopted criteria, was 95.54%, and the accuracy of its validation was 90.74%. The relative loss value during the training process of the SB3D-NET model was 18.53%, and during its validation process, it was 37.76%. The proposed SB3D-NET neural network model for all twenty-two criteria achieves values of global error (GE) of prediction and classification of seeds at the level of 0.0992. Full article
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20 pages, 5147 KB  
Article
Parameter-Free Model Predictive Control of Five-Phase PMSM Under Healthy and Inter-Turn Short-Circuit Fault Conditions
by Yijia Huang, Wentao Huang, Keyang Ru and Dezhi Xu
Energies 2025, 18(17), 4549; https://doi.org/10.3390/en18174549 - 27 Aug 2025
Abstract
Model predictive control offers high-performance regulation for multiphase drives but is critically dependent on the accuracy of mathematical models for prediction, making it vulnerable to parameter mismatches and uncertainties. To achieve parameter-independent control across both healthy and faulty operations, this paper proposes a [...] Read more.
Model predictive control offers high-performance regulation for multiphase drives but is critically dependent on the accuracy of mathematical models for prediction, making it vulnerable to parameter mismatches and uncertainties. To achieve parameter-independent control across both healthy and faulty operations, this paper proposes a novel dynamic mode decomposition with control (DMDc)-based model predictive current control (MPCC) scheme for five-phase permanent magnet synchronous motors. The core innovation lies in constructing discrete-time state-space models directly from operational data via the open-loop DMDc identification, completely eliminating reliance on explicit motor parameters. Furthermore, an improved fault-tolerant strategy is developed to mitigate the torque ripple induced by inter-turn short-circuit (ITSC) faults. This strategy estimates the key fault characteristic, the product of the short-circuit ratio and current, through a spectral decomposition of the AC component in the q-axis current variations, bypassing the need for complex parameter-dependent observers. The derived compensation currents are seamlessly integrated into the predictive control loop. Experimental results comprehensively validate the effectiveness of the proposed framework, demonstrating a performance comparable to a conventional MPCC under healthy conditions and a significant reduction in torque ripple under ITSC fault conditions, all achieved without any prior knowledge of motor parameters or the retuning of controller gains. Full article
(This article belongs to the Section E: Electric Vehicles)
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12 pages, 1597 KB  
Article
Cognitive Workload Assessment in Aerospace Scenarios: A Cross-Modal Transformer Framework for Multimodal Physiological Signal Fusion
by Pengbo Wang, Hongxi Wang and Heming Zhang
Multimodal Technol. Interact. 2025, 9(9), 89; https://doi.org/10.3390/mti9090089 - 26 Aug 2025
Viewed by 224
Abstract
In the field of cognitive workload assessment for aerospace training, existing methods exhibit significant limitations in unimodal feature extraction and in leveraging complementary synergy among multimodal signals, while current fusion paradigms struggle to effectively capture nonlinear dynamic coupling characteristics across modalities. This study [...] Read more.
In the field of cognitive workload assessment for aerospace training, existing methods exhibit significant limitations in unimodal feature extraction and in leveraging complementary synergy among multimodal signals, while current fusion paradigms struggle to effectively capture nonlinear dynamic coupling characteristics across modalities. This study proposes DST-Net (Cross-Modal Downsampling Transformer Network), which synergistically integrates pilots’ multimodal physiological signals (electromyography, electrooculography, electrodermal activity) with flight dynamics data through an Anti-Aliasing and Average Pooling LSTM (AAL-LSTM) data fusion strategy combined with cross-modal attention mechanisms. Evaluation on the “CogPilot” dataset for flight task difficulty prediction demonstrates that AAL-LSTM achieves substantial performance improvements over existing approaches (AUC = 0.97, F1 Score = 94.55). Given the dataset’s frequent sensor data missingness, the study further enhances simulated flight experiments. By incorporating eye-tracking features via cross-modal attention mechanisms, the upgraded DST-Net framework achieves even higher performance (AUC = 0.998, F1 Score = 97.95) and reduces the root mean square error (RMSE) of cumulative flight error prediction to 1750. These advancements provide critical support for safety-critical aviation training systems. Full article
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27 pages, 5560 KB  
Article
SOH Estimation of Lithium Battery Under Improved CNN-BIGRU-Attention Model Based on Hiking Optimization Algorithm
by Qianli Dong, Ziyang Liu, Hainan Wang, Lujun Wang, Rui Dong and Lu Lv
World Electr. Veh. J. 2025, 16(9), 487; https://doi.org/10.3390/wevj16090487 - 25 Aug 2025
Viewed by 135
Abstract
Accurate State of Health (SOH) estimation is critical for ensuring the safe operation of lithium-ion batteries. However, current data-driven approaches face significant challenges: insufficient feature extraction and ambiguous physical meaning compromise prediction accuracy, while initialization sensitivity to noise undermines stability; the inherent nonlinearity [...] Read more.
Accurate State of Health (SOH) estimation is critical for ensuring the safe operation of lithium-ion batteries. However, current data-driven approaches face significant challenges: insufficient feature extraction and ambiguous physical meaning compromise prediction accuracy, while initialization sensitivity to noise undermines stability; the inherent nonlinearity and temporal complexity of battery degradation data further lead to slow convergence or susceptibility to local optima. To address these limitations, this study proposes an enhanced CNN-BIGRU model. The model replaces conventional random initialization with a Hiking Optimization Algorithm (HOA) to identify superior initial weights, significantly improving early training stability. Furthermore, it integrates an Attention mechanism to dynamically weight features, strengthening the capture of key degradation characteristics. Rigorous experimental validation, utilizing multi-dimensional features extracted from the NASA dataset, demonstrates the model’s superior convergence speed and prediction accuracy compared to the CNN-BIGRU-Attention benchmark. Compared with other methods, the HOA-CNN-BIRGU-Attention model proposed in this study has a higher prediction accuracy and better robustness under different conditions, and the RMSEs on the NASA dataset are all controlled within 0.01, with R2 kept above 0.91. The RMSEs on the University of Maryland dataset are all below 0.006, with R2 kept above 0.98. Compared with the CNN-BIGRU-ATTENTION baseline model without HOA optimization, the RMSE is reduced by at least 0.15% across different battery groups in the NASA dataset. Full article
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23 pages, 2967 KB  
Article
Ultra-Short-Term Wind Power Prediction Based on Spatiotemporal Contrastive Learning
by Jie Xu, Tie Chen, Jiaxin Yuan, Youyuan Fan, Liping Li and Xinyu Gong
Electronics 2025, 14(17), 3373; https://doi.org/10.3390/electronics14173373 - 25 Aug 2025
Viewed by 227
Abstract
With the accelerating global energy transition, wind power has become a core pillar of renewable energy systems. However, its inherent intermittency and volatility pose significant challenges to the safe, stable, and economical operation of power grids—making ultra-short-term wind power prediction a critical technical [...] Read more.
With the accelerating global energy transition, wind power has become a core pillar of renewable energy systems. However, its inherent intermittency and volatility pose significant challenges to the safe, stable, and economical operation of power grids—making ultra-short-term wind power prediction a critical technical link in optimizing grid scheduling and promoting large-scale wind power integration. Current forecasting techniques are plagued by problems like the inadequate representation of features, the poor separation of features, and the challenging clarity of deep learning models. This study introduces a method for the prediction of wind energy using spatiotemporal contrastive learning, employing seasonal trend decomposition to encapsulate the diverse characteristics of time series. A contrastive learning framework and a feature disentanglement loss function are employed to effectively decouple spatiotemporal features. Data on geographical positions are integrated to simulate spatial correlations, and a convolutional network of spatiotemporal graphs, integrated with a multi-head attention system, is crafted to improve the clarity. The proposed method is validated using operational data from two actual wind farms in Northwestern China. The research indicates that, compared with typical baselines (e.g., STGCN), this method reduces the RMSE by up to 38.47% and the MAE by up to 44.71% for ultra-short-term wind power prediction, markedly enhancing the prediction precision and offering a more efficient way to forecast wind power. Full article
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23 pages, 7350 KB  
Article
Mechanisms of Spatial Coupling Between Plantation Species Distribution and Historical Disturbance in the Complex Topography of Eastern Yunnan
by Xiyu Zhang, Chao Zhang and Lianjin Fu
Remote Sens. 2025, 17(17), 2925; https://doi.org/10.3390/rs17172925 - 22 Aug 2025
Viewed by 376
Abstract
Forest disturbance is a major driver shaping the structure and function of plantation ecosystems. Current research predominantly focuses on single forest types or landscape scales. However, species-level fine-scale assessments of disturbance dynamics are still scarce. In this study, we investigated Chinese fir ( [...] Read more.
Forest disturbance is a major driver shaping the structure and function of plantation ecosystems. Current research predominantly focuses on single forest types or landscape scales. However, species-level fine-scale assessments of disturbance dynamics are still scarce. In this study, we investigated Chinese fir (Cunninghamia lanceolata), Armand pine (Pinus armandii), and Yunnan pine (Pinus yunnanensis) plantations in the mountainous eastern Yunnan Plateau. We developed a Spatial Coupling Framework of Disturbance Legacy (SC-DL) to systematically elucidate the spatial associations between contemporary species distribution patterns and historical disturbance regimes. Using the Google Earth Engine (GEE) platform, we reconstructed pixel-level disturbance trajectories by integrating long-term Landsat time series (1993–2024) and applying the LandTrendr algorithm. By fusing multi-source remote sensing features (Sentinel-1/2) with terrain factors, employing RFE, and performing a multi-model comparison, we generated 10 m-resolution species distribution maps for 2024. Spatial overlay analysis quantified the cumulative proportion of the historically disturbed area and the spatial aggregation patterns of historical disturbances within current species ranges. Key results include the following: (1) The model predicting disturbance year achieved high accuracy (R2 = 0.95, RMSE = 2.02 years, MAE = 1.15 years). The total disturbed area from 1993 to 2024 was 872.7 km2, exhibiting three distinct phases. (2) The random forest (RF) model outperformed other classifiers, achieving an overall accuracy (OA) of 95.17% and a Kappa coefficient (K) of 0.93. Elevation was identified as the most discriminative feature. (3) Significant spatial differentiation in disturbance types emerged: anthropogenic disturbances (e.g., logging and reforestation/afforestation) dominated (63.1% of total disturbed area), primarily concentrated within Chinese fir zones (constituting 70.2% of disturbances within this species’ range). Natural disturbances accounted for 36.9% of the total, with fire dominating within the Yunnan pine range (79.3% of natural disturbances in this zone) and drought prevailing in the Armand pine range (71.3% of natural disturbances in this zone). (4) Cumulative disturbance characteristics differed markedly among species zones: Chinese fir zones exhibited the highest cumulative proportion of disturbed area (42.6%), with strong spatial aggregation. Yunnan pine zones followed (36.5%), exhibiting disturbances linearly distributed along dry–hot valleys. Armand pine zones showed the lowest proportion (20.9%), characterized by sparse disturbances within fragmented, high-altitude habitats. These spatial patterns reflect the combined controls of topographic adaptation, management intensity, and environmental stress. Our findings establish a scientific basis for identifying disturbance-prone areas and inform the development of differentiated precision management strategies for plantations. Full article
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22 pages, 2937 KB  
Article
Recurrent Neural Networks (LSTM and GRU) in the Prediction of Current–Voltage Characteristics Curves of Polycrystalline Solar Cells
by Rodrigo R. Chaves, Adhimar F. Oliveira, Rero M. Rubinger and Alessandro J. Silva
Electronics 2025, 14(17), 3342; https://doi.org/10.3390/electronics14173342 - 22 Aug 2025
Viewed by 293
Abstract
The current–voltage (I-V) characteristic provides essential performance parameters of a solar cell, influenced by temperature and solar radiation. The efficiency of a solar cell is sensitive to variations in these conditions. This study electrically characterized a polycrystalline silicon solar cell in a solar [...] Read more.
The current–voltage (I-V) characteristic provides essential performance parameters of a solar cell, influenced by temperature and solar radiation. The efficiency of a solar cell is sensitive to variations in these conditions. This study electrically characterized a polycrystalline silicon solar cell in a solar simulator chamber at temperatures of 25–55 °C and irradiance levels of 600–1000 W/m2. The acquired data were used to train and evaluate neural network models to predict the I-V characteristics of a polycrystalline silicon solar cell. Two recurrent neural network architectures were tested: LSTM and the GRU model. The performance of the model was assessed using MAE, RMSE, and R2. The GRU model achieved the results, with MAE = 2.813×103, RMSE = 5.790×103, and R2 = 0.9844, similar to LSTM (MAE = 2.6613×103, RMSE = 5.858×103, R2 = 0.9840). These findings highlight the GRU network as the most efficient approach for modeling solar cell behavior under varying environmental conditions. Full article
(This article belongs to the Section Artificial Intelligence)
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16 pages, 2672 KB  
Review
Conformational and Functional Properties of the Bioactive Thiosemicarbazone and Thiocarbohydrazone Compounds
by Nikitas Georgiou, Ektoras Vasileios Apostolou, Stamatia Vassiliou, Demeter Tzeli and Thomas Mavromoustakos
Curr. Issues Mol. Biol. 2025, 47(9), 676; https://doi.org/10.3390/cimb47090676 - 22 Aug 2025
Viewed by 367
Abstract
Thiosemicarbazones and thiocarbohydrazones are key sulfur-containing organic compounds known for their diverse biological, pharmaceutical, and industrial applications. Beyond their well-established therapeutic potential, their strong chelating ability allows them to form stable complexes with transition metals, enabling uses in catalysis, corrosion inhibition, and dyeing [...] Read more.
Thiosemicarbazones and thiocarbohydrazones are key sulfur-containing organic compounds known for their diverse biological, pharmaceutical, and industrial applications. Beyond their well-established therapeutic potential, their strong chelating ability allows them to form stable complexes with transition metals, enabling uses in catalysis, corrosion inhibition, and dyeing processes. Their structural characteristics and dynamic conformations critically influence both biological activity and industrial performance, making nuclear magnetic resonance (NMR) spectroscopy an indispensable tool for their analysis. This review provides a comprehensive overview of the conformational and functional properties of bioactive thiosemicarbazones and thiocarbohydrazones, with a focus on how experimental NMR techniques are used to investigate their conformational behavior. In addition to experimental findings, available computational data are discussed, offering complementary insights into their structural dynamics. The integration of experimental and theoretical approaches offers a robust framework for predicting the behavior and interactions of these compounds, thereby informing the rational design of novel derivatives with improved functionality. By highlighting key structural features and application contexts, this work addresses a critical gap in the current understanding of these promising agents across both biomedical and industrial domains. Full article
(This article belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
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12 pages, 269 KB  
Article
Predictors of Emotional Exhaustion and Depersonalization in Teachers After the COVID-19 Pandemic: Implications for Mental Health and Psychiatric Support in Spanish-Speaking Countries
by Sofia Catalina Arango-Lasprilla, Natalia Albaladejo-Blázquez, Bryan R. Christ, Oswaldo A. Moreno, Maria Camila Gomez Posada, Paul B. Perrin and Rosario Ferrer-Cascales
Psychiatry Int. 2025, 6(3), 101; https://doi.org/10.3390/psychiatryint6030101 - 21 Aug 2025
Viewed by 370
Abstract
Burnout, characterized by emotional exhaustion and depersonalization, is increasingly recognized as a significant mental health concern with psychiatric implications. This cross-sectional study explored variables associated with current burnout levels among 2004 teachers in 19 Latin American countries and Spain, drawing on retrospective perceptions [...] Read more.
Burnout, characterized by emotional exhaustion and depersonalization, is increasingly recognized as a significant mental health concern with psychiatric implications. This cross-sectional study explored variables associated with current burnout levels among 2004 teachers in 19 Latin American countries and Spain, drawing on retrospective perceptions of COVID-19 pandemic-related changes in work conditions and student behavior. Using a comprehensive survey, researchers gathered demographic information, work-related characteristics, and burnout levels measured by the Maslach Burnout Inventory. Participants were recruited through social media platforms and teacher groups. Participants reported high emotional exhaustion, with 45.9% exceeding the clinical threshold. Moderate depersonalization levels were observed, with 30.2% scoring above the clinical cutoff. Hierarchical regressions indicated that emotional exhaustion was significantly predicted by individual (e.g., gender, age, socioeconomic status, pre-existing mental and chronic illnesses), school (e.g., school level, sector, and workload), and student factors (e.g., behavior and social adjustment problems), accounting for 17.4% of the variance. Depersonalization was similarly associated with individual (e.g., gender, age, education, and pre-existing mental illness), school (e.g., workload and school level), and student characteristics (e.g., educational, behavioral, and family adjustment problems), explaining 6.5% of the variance. These findings contribute to psychiatric and psychological research by identifying specific risk profiles for chronic stress syndromes in educators—an occupational group facing long-term psychological impacts from the COVID-19 crisis. This study underscores the need for interdisciplinary psychiatric approaches to diagnose and prevent burnout and promote teacher well-being through clinical and policy-level interventions. Full article
36 pages, 2647 KB  
Article
Mechanism and Kinetics of Non-Electroactive Chlorate Electroreduction via Catalytic Redox-Mediator Cycle Without Catalyst’s Addition (EC-Autocat Process)
by Mikhail A. Vorotyntsev, Pavel A. Zader, Olga A. Goncharova and Dmitry V. Konev
Molecules 2025, 30(16), 3432; https://doi.org/10.3390/molecules30163432 - 20 Aug 2025
Viewed by 420
Abstract
In the context of chlorate’s application as a cathodic reagent of power sources, the mechanism of its electroreduction has been studied in electrochemical cells under diffusion-limited current conditions with operando spectrophotometric analysis. Prior to electrolysis, the electrolyte is represented as an aqueous mixed [...] Read more.
In the context of chlorate’s application as a cathodic reagent of power sources, the mechanism of its electroreduction has been studied in electrochemical cells under diffusion-limited current conditions with operando spectrophotometric analysis. Prior to electrolysis, the electrolyte is represented as an aqueous mixed NaClO3 + H2SO4 solution (both components being non-electroactive within the potential range under study), without addition of any external electroactive catalyst. In the course of potentiostatic electrolysis, both the cathodic current and the ClO2 concentration demonstrate a temporal evolution clearly pointing to an autocatalytic mechanism of the process (regions of quasi-exponential growth and of rapid diminution, separated by a narrow maximum). It has been substantiated that its kinetic mechanism includes only one electrochemical step (chlorine dioxide reduction), coupled with two chemical steps inside the solution phase: comproportionation of chlorate anion and chlorous acid, as well as chlorous acid disproportionation via two parallel routes. The corresponding set of kinetic equations for the concentrations of Cl-containing solute components (ClO3, ClO2, HClO2, and Cl) has been solved numerically in a dimensionless form. Optimal values of the kinetic parameters have been determined via a fitting procedure with the use of non-stationary experimental data for the ClO2 concentration and for the current, taking into account the available information from the literature on the parameters of the chlorous acid disproportionation process. Predictions of the proposed kinetic mechanism agree quantitatively with these experimental data for both quantities within the whole time range, including the three characteristic regions: rapid increase, vicinity of the maximum, and rapid decrease. Full article
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25 pages, 9065 KB  
Article
PWFNet: Pyramidal Wavelet–Frequency Attention Network for Road Extraction
by Jinkun Zong, Yonghua Sun, Ruozeng Wang, Dinglin Xu, Xue Yang and Xiaolin Zhao
Remote Sens. 2025, 17(16), 2895; https://doi.org/10.3390/rs17162895 - 20 Aug 2025
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Abstract
Road extraction from remote sensing imagery plays a critical role in applications such as autonomous driving, urban planning, and infrastructure development. Although deep learning methods have achieved notable progress, current approaches still struggle with complex backgrounds, varying road widths, and strong texture interference, [...] Read more.
Road extraction from remote sensing imagery plays a critical role in applications such as autonomous driving, urban planning, and infrastructure development. Although deep learning methods have achieved notable progress, current approaches still struggle with complex backgrounds, varying road widths, and strong texture interference, often leading to fragmented road predictions or the misclassification of background regions. Given that roads typically exhibit smooth low-frequency characteristics while background clutter tends to manifest in mid- and high-frequency ranges, incorporating frequency-domain information can enhance the model’s structural perception and discrimination capabilities. To address these challenges, we propose a novel frequency-aware road extraction network, termed PWFNet, which combines frequency-domain modeling with multi-scale feature enhancement. PWFNet comprises two key modules. First, the Pyramidal Wavelet Convolution (PWC) module employs multi-scale wavelet decomposition fused with localized convolution to accurately capture road structures across various spatial resolutions. Second, the Frequency-aware Adjustment Module (FAM) partitions the Fourier spectrum into multiple frequency bands and incorporates a spatial attention mechanism to strengthen low-frequency road responses while suppressing mid- and high-frequency background noise. By integrating complementary modeling from both spatial and frequency domains, PWFNet significantly improves road continuity, edge clarity, and robustness under complex conditions. Experiments on the DeepGlobe and CHN6-CUG road datasets demonstrate that PWFNet achieves IoU improvements of 3.8% and 1.25% over the best-performing baseline methods, respectively. In addition, we conducted cross-region transfer experiments by directly applying the trained model to remote sensing images from different geographic regions and at varying resolutions to assess its generalization capability. The results demonstrate that PWFNet maintains the continuity of main and branch roads and preserves edge details in these transfer scenarios, effectively reducing false positives and missed detections. This further validates its practicality and robustness in diverse real-world environments. Full article
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