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Search Results (6,042)

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Keywords = cultural knowledge

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18 pages, 1015 KB  
Article
Context-Aware Semantic Retrieval for Ancient Texts: A Native Reasoning Approach Based on In-Memory Knowledge Graph
by Tianrui Li and Hongyu Yuan
Electronics 2026, 15(9), 1827; https://doi.org/10.3390/electronics15091827 (registering DOI) - 25 Apr 2026
Abstract
This paper presents a lightweight semantic retrieval framework driven by an in-memory knowledge graph (IMKG) to overcome the limitations of traditional keyword matching and the prohibitive hardware costs of deep learning models in digitizing ancient Chinese literature. By extracting structured metadata from canonical [...] Read more.
This paper presents a lightweight semantic retrieval framework driven by an in-memory knowledge graph (IMKG) to overcome the limitations of traditional keyword matching and the prohibitive hardware costs of deep learning models in digitizing ancient Chinese literature. By extracting structured metadata from canonical texts, we construct a dense, bidirectional graph schema. Diverging from resource-intensive neural architectures, our system abandons heavyweight vector embeddings in favor of a highly optimized, template-based heuristic matching engine natively implemented in Java. This purely symbolic approach ensures deterministic execution, zero-dependency deployment, and seamless operation on standard CPU-only servers. To handle complex historical inquiries, the framework integrates a context-aware dialogue manager for multi-turn anaphora and ellipsis resolution, alongside a synergistic tiered caching mechanism. Extensive evaluations on a benchmark of 13,652 annotated queries demonstrate that the system achieves an exceptional intent recognition accuracy of 97.14%, robust context retention, and ultra-low response latency (≤17 ms). Ultimately, this architecture provides a sustainable, highly reproducible, and cost-effective paradigm for the semantic exploration of classical textual heritage, exceptionally suited for small-to-medium cultural institutions. Full article
20 pages, 2282 KB  
Article
Ethnobotanical Knowledge and the Distribution of Pesticidal Plants in Northern Tanzania: A Multi-Ethnic Perspective
by Immaculate K. Constantine, Richard A. Giliba and Angela G. Mkindi
Diversity 2026, 18(5), 253; https://doi.org/10.3390/d18050253 (registering DOI) - 25 Apr 2026
Abstract
Pesticidal plants are vital for pest management in sub-Saharan Africa, yet knowledge about them is culturally and geographically unevenly documented. This study examined ethnobotanical knowledge and the distribution of pesticidal plants among six ethnic groups (Maasai, Chagga, Iraqw, Pare, Nguu, Zigua) in northern [...] Read more.
Pesticidal plants are vital for pest management in sub-Saharan Africa, yet knowledge about them is culturally and geographically unevenly documented. This study examined ethnobotanical knowledge and the distribution of pesticidal plants among six ethnic groups (Maasai, Chagga, Iraqw, Pare, Nguu, Zigua) in northern Tanzania. Data related to ethnobotanical knowledge were collected from questionnaire surveys involving 266 participants, 24 focus group discussions, 26 key informant interviews, complemented by field verifications across the six ethnic groups. Pesticidal plant coordinates were accessed from herbarium voucher specimens from The National Herbarium of Tanzania. Chi-square tests of independence assessed associations between ethnic groups and knowledge transmission pathways. Penalized logistic regression analysis was conducted to assess the influence of demographic factors on reported knowledge of pesticidal plants. Spatial overlay was conducted to examine the distribution of pesticidal plant species occurrences across agroecological zones and rainfall gradients. The results revealed a significant association between ethnic group and the source of pesticidal plant knowledge. Across all ethnic groups, knowledge was predominantly acquired through family/community traditional sources, with the highest frequencies recorded among the Maasai, Iraqw, and Zigua. Knowledge is mainly transmitted orally, particularly among the Maasai, Iraqw, and Zigua. A total of one hundred and six distinct species were recorded across the six ethnic groups surveyed, with Tephrosia vogelii and Solanum incanum being the most frequently cited. Leaves were the most frequently used plant part across all ethnic groups, with notably high usage among the Chagga, Iraqw, and Maasai. Perceptions of the declining population of pesticidal plants were the highest among the Maasai. Spatial mapping revealed pesticidal plant hotspots in the Northern Rift and Volcanic Highlands agroecological zones, and they fall within zones receiving moderate to relatively high rainfall. The findings highlight that ethnobotanical knowledge of pesticidal plants in northern Tanzania is strongly shaped by ethnic affiliation, oral knowledge transmission, and localized ecological availability, with clear spatial hotspots aligned to specific agroecological zones and high-rainfall areas. Full article
(This article belongs to the Special Issue Socioecology and Biodiversity Conservation—2nd Edition)
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18 pages, 701 KB  
Review
The Role of Athlete Support Personnel in Anti-Doping: A Narrative Review of Contemporary Evidence
by Iván Martín-Miguel, Millán Aguilar-Navarro, Juan Del Coso, Arturo Franco-Andrés, Carolina García and Alejandro Muñoz
Healthcare 2026, 14(9), 1147; https://doi.org/10.3390/healthcare14091147 - 24 Apr 2026
Abstract
Doping remains a major threat to athlete health and sport integrity. Although anti-doping efforts have traditionally focused on athletes, increasing attention has turned to Athlete Support Personnel (ASP) due to their influence on athletes’ decisions, behaviors and involvement in anti-doping rule violations. This [...] Read more.
Doping remains a major threat to athlete health and sport integrity. Although anti-doping efforts have traditionally focused on athletes, increasing attention has turned to Athlete Support Personnel (ASP) due to their influence on athletes’ decisions, behaviors and involvement in anti-doping rule violations. This narrative review aimed to synthesize the existing literature on the role of ASP (including coaches, physicians, pharmacists, sport psychologists, nutritionists, physiotherapists, parents and other family members) in anti-doping, with particular attention to their influence on athletes’ knowledge, attitudes, behaviors, education and decision-making related to doping. Coaches, physicians, and pharmacists are among the ASP groups most frequently examined in the literature, although substantial knowledge gaps remain across all groups. Coaches shape motivational climates and ethical norms but often lack adequate understanding of anti-doping regulations and supplement risks. Physicians and pharmacists play key roles in medication management and Therapeutic Use Exemptions procedures, though incomplete regulatory knowledge may contribute to inadvertent violations. Nutritionists are central in preventing supplement-related doping, while research on sport psychologists and physiotherapists remains limited despite their preventive potential. Parents significantly shape athletes’ moral development and susceptibility to doping, acting as protective or risk factors depending on family dynamics. Overall, anti-doping education for ASP remains inconsistent. In conclusion, ASP plays an essential yet heterogeneous role in influencing doping-related behaviors. Strengthening role-specific and interdisciplinary anti-doping education, particularly within university programs and professional development, appears critical for enhancing ASP competence and promoting a sustainable culture of clean sport. Full article
12 pages, 342 KB  
Article
Knowledge, Attitudes, Motivations, and Practices of Blood Donation Among the Population of Saudi Arabia
by Saud Ibrahim Altilasi, Dima Hamze, Mazin Elsarrag, Muhammad Raihan Sajid and Salman Aldosari
Healthcare 2026, 14(9), 1143; https://doi.org/10.3390/healthcare14091143 - 24 Apr 2026
Abstract
Background/Objectives: Blood donation is a critical component of healthcare systems worldwide, yet donor recruitment remains challenging. This study evaluates the knowledge, attitudes, motivations, and practices (KAP) of blood donation among the general population in Saudi Arabia to identify key barriers and propose [...] Read more.
Background/Objectives: Blood donation is a critical component of healthcare systems worldwide, yet donor recruitment remains challenging. This study evaluates the knowledge, attitudes, motivations, and practices (KAP) of blood donation among the general population in Saudi Arabia to identify key barriers and propose targeted interventions. Methods: A cross-sectional study was conducted using a structured, validated questionnaire distributed over five months (December 2022 to April 2023) via social media and in-person recruitment at the Central Blood Bank in Riyadh. A total of 1150 participants aged 18–60 years residing in Saudi Arabia were included in the final analysis. Statistical analysis was performed using SPSS version 22, with p < 0.05 considered significant. Results: Participants demonstrated moderate knowledge (mean score 5.43 ± 1.81 out of 9), with significantly higher scores among males, individuals aged 21–30 years, and those holding a bachelor’s degree. Attitudes toward donation were highly positive (mean score 15.46 ± 2.74 out of 20) and correlated with age, gender, marital status, and occupation. Despite this positive outlook, only 34.96% of participants had donated blood previously, although 95.25% expressed willingness to do so. Primary motivators included mobile donation units (89.22%) and paid leave (89.22%), whereas 51.22% of respondents considered current media campaigns ineffective. Common barriers to donation included health concerns (25.30%), time constraints (12.87%), and fear of needles (7.74%). Conclusions: This study reveals a critical disparity between positive public attitudes and actual donation practices in Saudi Arabia. To enhance donor participation, we recommend implementing convenient donation strategies such as mobile blood drives, workplace incentives, and more effective, culturally tailored educational campaigns. Addressing these factors could help Saudi Arabia improve its voluntary donation rates and ensure a sustainable, safe blood supply. Full article
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18 pages, 4055 KB  
Article
Whole-Genome Phylogenetic Characterization of Human Parainfluenza Virus Type 4 Circulating in St. Petersburg, Russia
by Oula Mansour, Artem V. Fadeev, Alexander A. Perederiy, Andrey D. Ksenafontov, Anastasiia Y. Boyarintseva, Daria M. Danilenko, Dmitry A. Lioznov and Andrey B. Komissarov
Viruses 2026, 18(5), 497; https://doi.org/10.3390/v18050497 (registering DOI) - 24 Apr 2026
Abstract
Human parainfluenza virus type 4 (hPIV4) remains poorly characterized compared with other hPIV serotypes and information on its genomic diversity is particularly limited for Russia and Eastern Europe. In this study, we report the first complete genome sequences of hPIV4 isolates from Russia [...] Read more.
Human parainfluenza virus type 4 (hPIV4) remains poorly characterized compared with other hPIV serotypes and information on its genomic diversity is particularly limited for Russia and Eastern Europe. In this study, we report the first complete genome sequences of hPIV4 isolates from Russia and place them in the context of global hPIV4 genetic diversity. Eight hPIV4 viruses were isolated in cell culture from respiratory samples collected from hospitalized children in Saint Petersburg between 2017/2018 and 2023/2024. Complete viral genomes were recovered using a metagenomic whole-genome amplification approach based on SMART-9N technology. Phylogenetic analysis of 178 complete hPIV4 genomes showed clear separation into hPIV4a (n = 132) and hPIV4b (n = 46) subtypes. Based on genetic distance approach, hPIV4a formed two major clusters, with the dominant cluster B subdivided into four subclusters (B1–B4); and subcluster B4 further resolved into four genetic lineages. All Russian isolates belonged to the subcluster B4 and were distributed among multiple co-circulating lineages. In contrast, hPIV4b genomes segregated into three distinct clusters, reflecting structured genetic diversity within the subtype. Collectively, this study provides, to the best of our knowledge, the first p-distance-based framework for hPIV4 whole-genome classification and contributes new complete genome sequences for an underrepresented region. Full article
(This article belongs to the Section Human Virology and Viral Diseases)
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20 pages, 802 KB  
Brief Report
Artifact Construction Illuminating Wellbeing Amongst Saudi Arabian Women Academic Leaders: A Methodological Mapping in Four Artifacts
by Claire Alkouatli and Rasis Alanazi
Educ. Sci. 2026, 16(5), 680; https://doi.org/10.3390/educsci16050680 - 24 Apr 2026
Abstract
This paper reports upon the visual research methodology of artifact construction employed in semi-structured interviews to explore how Saudi women in academic leadership positions cultivate and maintain wellbeing. Ten Saudi Arabian women academic leaders were invited to draw, diagram, or annotate how they [...] Read more.
This paper reports upon the visual research methodology of artifact construction employed in semi-structured interviews to explore how Saudi women in academic leadership positions cultivate and maintain wellbeing. Ten Saudi Arabian women academic leaders were invited to draw, diagram, or annotate how they cultivate, maintain, and express wellbeing in a rapidly changing cultural context. Four exemplary artifacts were selected for analysis. Findings include that while semi-structured interviewing made themes visible, artifact construction extended the themes and illuminated unique aspects of the research question. Specifically, the artifacts illustrate wellbeing as holistic, interwoven of hedonic and eudaimonic aspects, and positioning self and others in a lattice of being well. It is intentional, balanced, spiritually sourced and sustained. It is generous and generative, animating abundance as both a process and a product of wellbeing. The artifacts are more than just a visual complement to the research story; they methodologically tap into the research question differently than verbal methods alone. While not every research participant accepted the invitation to construct an artifact, and methodological drawbacks are considered, the ones who did accept the invitation demonstrated that artifact construction captures complexity at the conceptual intersection of wellbeing and female academic leadership. This paper contributes new knowledge on the efficacy of artifact construction; in this case, in research sites beyond culturally ‘western’ ones. Full article
(This article belongs to the Special Issue Educational Leadership Complexity: Theories, Methods, and Practices)
24 pages, 4530 KB  
Article
A Crowdsourcing-Based Digital Storytelling Platform for Preserving Intangible Cultural Heritage: A Case Study of Southern Thai Textiles
by Supaporn Chai-Arayalert, Supattra Puttinaovarat and Wanida Saetang
Heritage 2026, 9(5), 160; https://doi.org/10.3390/heritage9050160 - 24 Apr 2026
Abstract
The preservation of tacit knowledge embedded in Southern Thai textiles remains a significant challenge because much of this knowledge is dispersed across private households and is inadequately supported by conventional object-centered documentation systems. This study developed a crowdsourcing-based digital storytelling platform that enabled [...] Read more.
The preservation of tacit knowledge embedded in Southern Thai textiles remains a significant challenge because much of this knowledge is dispersed across private households and is inadequately supported by conventional object-centered documentation systems. This study developed a crowdsourcing-based digital storytelling platform that enabled communities to document, organize, and disseminate knowledge related to Southern Thai textile heritage. The platform integrated community participation, structured narrative authoring, and knowledge organization within a socio-technical system designed for cultural heritage documentation. To guide its development, the study proposed the Crowdsourced-Storytelling Intangible Cultural Heritage Framework (CS-ICH Framework) and operationalizes it through requirements analysis, iterative prototyping, and empirical user evaluation. The evaluation results indicated high levels of user satisfaction and positive user perceptions regarding knowledge accessibility, content organization, and the platform’s support for heritage preservation. These findings suggested that participatory digital platforms can effectively facilitate the documentation and dissemination of locally embedded cultural knowledge that is difficult to capture through conventional institutional systems. This study contributed to digital heritage research by providing a potentially transferable framework and design principles for integrating crowdsourcing and digital storytelling within platforms designed to preserve and transmit intangible and community-held cultural heritage. Full article
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19 pages, 587 KB  
Article
Rebus-Based Instruction as a Sustainable Pedagogical Approach for Citizenship and Cultural Sustainability: Enhancing Gifted Students’ Learning of Mesopotamian and Anatolian Civilizations
by Beyza Turan Korkutata and Mustafa İçen
Sustainability 2026, 18(9), 4220; https://doi.org/10.3390/su18094220 - 23 Apr 2026
Abstract
This study examined the potential of rebus-based instruction as a visually enriched pedagogical approach for supporting gifted students’ learning of Mesopotamian and Anatolian civilizations. Within the framework of sustainable education, the study focused on instructional practices that promote meaningful learning, active cognitive engagement, [...] Read more.
This study examined the potential of rebus-based instruction as a visually enriched pedagogical approach for supporting gifted students’ learning of Mesopotamian and Anatolian civilizations. Within the framework of sustainable education, the study focused on instructional practices that promote meaningful learning, active cognitive engagement, and the short-term retention of knowledge, particularly in relation to cultural and historical understanding. A mixed-methods research design was employed. Quantitative data were collected through a pre-test–post-test quasi-experimental design, while qualitative data were obtained through semi-structured interviews. The study group consisted of 18 gifted students enrolled in a Science and Art Center (BILSEM) in Istanbul during the 2024–2025 academic year. Of these, 11 students were assigned to the experimental group and 7 to the control group. The experimental group received rebus-based instruction, whereas the control group was taught using traditional teaching methods. Quantitative findings showed a statistically significant improvement in the academic achievement scores of the students in the experimental group compared with their pre-test scores. Qualitative findings further indicated that rebus-based instruction enhanced students’ motivation, creativity, visual perception, and analytical thinking, while also supporting meaningful learning and short-term recall over a one-month interval. In addition, students demonstrated an improved ability to recall and accurately identify historical civilizations. Overall, the findings suggest that rebus-based instruction may be a promising pedagogical approach for promoting engaging and meaningful learning experiences and for supporting the teaching of cultural and historical knowledge in gifted education. Full article
18 pages, 37561 KB  
Article
Resilience and Response: Understanding Community’s Policy Perspectives on Flood and Erosion in Assam
by Abhinandan Saikia, Chinmoyee Deka and Ranit Chatterjee
Sustainability 2026, 18(9), 4216; https://doi.org/10.3390/su18094216 - 23 Apr 2026
Abstract
As a chronic flood and erosion-prone region in India, Assam faces perpetual challenges in managing and mitigating the impacts of natural hazards every year. Despite participatory policy and communication approaches, communities in the region do not feel included in the planning and decision-making [...] Read more.
As a chronic flood and erosion-prone region in India, Assam faces perpetual challenges in managing and mitigating the impacts of natural hazards every year. Despite participatory policy and communication approaches, communities in the region do not feel included in the planning and decision-making processes of mitigation and prevention. The study conducts a stakeholder perception analysis using a qualitative approach through Focus Group Discussions (FGDs) and semi-structured and structured interviews with flood-prone communities of Barpeta, Dibrugarh, and Majuli districts in Assam. The thematic analysis revealed multiple gaps in the policy planning and implementation stages where the traditional knowledge of communities has been ignored, while also revealing gendered silences and communication fallouts. The increasing frequency and intensity of floods, along with untimely modern interventions, have convinced communities to combine modern mitigation strategies with their traditional mitigation strategies like stilt houses, but engineers and policymakers often bypass the traditional knowledge of communities. The study calls for a multi-faceted approach to flood and erosion management by addressing the infrastructural and socio-cultural challenges, and involving communities more actively in the planning and decision-making processes, re-emphasizing the importance of SDG 13 and SDG 17. Full article
(This article belongs to the Special Issue Sustainable Disaster Management and Community Resilience)
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19 pages, 931 KB  
Article
Cultural Competence and Loneliness: Unveiling Hidden Connections Among Saudi Nurses
by Rasha Mohammed Hussien, Ghida Saleh Algeffari, Mahmoud Abdelwahab Khedr and Wafa Hamad Almegewly
Behav. Sci. 2026, 16(5), 631; https://doi.org/10.3390/bs16050631 (registering DOI) - 23 Apr 2026
Abstract
Background: Cultural competence is essential in nursing, enabling the delivery of ethical, patient-centered, and respectful care that respects diverse cultural backgrounds in an increasingly diverse healthcare setting. Improving cultural competence can substantially reduce stereotyping, time pressure, and distress among nurses. Objective: This study [...] Read more.
Background: Cultural competence is essential in nursing, enabling the delivery of ethical, patient-centered, and respectful care that respects diverse cultural backgrounds in an increasingly diverse healthcare setting. Improving cultural competence can substantially reduce stereotyping, time pressure, and distress among nurses. Objective: This study aimed to examine the relationship between cultural competence and loneliness among nurses working at a university medical city in Saudi Arabia and to identify associated demographic and psychological factors. Methods: A descriptive cross-sectional study was conducted using a convenience sample of 184 nurses. Data were collected via an online questionnaire that included the Cultural Capacity Scale, the Revised UCLA Loneliness Scale, and the Patient Health Questionnaire-4 between April and May 2024. Descriptive statistics, Spearman’s correlation, and multiple linear regression were used in the data analysis. Result: Findings indicate high cultural competence (mean score: 78.82) but moderate loneliness (mean score: 11.9). Notably, a strong negative correlation exists between cultural competence and feelings of loneliness (r = −0.777) and anxiety/depression (r = −0.818), suggesting that increased cultural competence is associated with lower loneliness and mental health issues. Conclusions: Both cultural knowledge and sensitivity emerged as significant predictors of lower anxiety and depression levels. These findings highlight the association between cultural competence and reduced loneliness and psychological distress among nurses, suggesting the need for targeted training interventions to improve nurses’ well-being and the quality of patient-centered care in culturally diverse healthcare settings. Full article
14 pages, 345 KB  
Article
A New Investigation into the Confucian Translations and Interpretations of Claude de Visdelou S.I.
by Ying Luo
Religions 2026, 17(5), 510; https://doi.org/10.3390/rel17050510 - 23 Apr 2026
Viewed by 141
Abstract
Claude de Visdelou, a French Jesuit missionary who arrived in China in the 17th century, was renowned for his remarkable linguistic talent and profound knowledge of Sinology. He left behind numerous Latin translations of Chinese classics, many of which were preserved in manuscript [...] Read more.
Claude de Visdelou, a French Jesuit missionary who arrived in China in the 17th century, was renowned for his remarkable linguistic talent and profound knowledge of Sinology. He left behind numerous Latin translations of Chinese classics, many of which were preserved in manuscript form and are currently held in Biblioteca Apostolica Vaticana. Based on an examination of Visdelou’s life and his Latin translations of Confucian documents, such as Daxue, this paper aims to analyze the complex reasons why Visdelou openly opposed the Jesuit policy of tolerance toward Chinese rituals and was promoted by the Roman Curia for his opposition to the Jesuit’s approach. The paper also reflects on his translation activities as a personal intellectual struggle and as a means of cross-cultural knowledge construction from the perspective of Sino-Western cultural exchange history. Full article
(This article belongs to the Section Religions and Humanities/Philosophies)
15 pages, 652 KB  
Review
A Comparative Analysis of Pre-Exposure Prophylaxis Awareness, Acceptance, and Barriers Among Populations of Men Who Have Sex with Men in Global Settings: An Integrative Literature Review
by Won Ju Hwang, Hwiyun Kim and Nancy R. Reynolds
Nurs. Rep. 2026, 16(5), 148; https://doi.org/10.3390/nursrep16050148 - 22 Apr 2026
Viewed by 133
Abstract
Background: Although pre-exposure prophylaxis (PrEP) has demonstrated strong clinical efficacy in preventing HIV infection among men who have sex with men (MSM), real-world utilization remains suboptimal. In South Korea, MSM constitute a major population within the domestic HIV epidemic; however, PrEP uptake [...] Read more.
Background: Although pre-exposure prophylaxis (PrEP) has demonstrated strong clinical efficacy in preventing HIV infection among men who have sex with men (MSM), real-world utilization remains suboptimal. In South Korea, MSM constitute a major population within the domestic HIV epidemic; however, PrEP uptake has not increased pro-portionally to awareness. This discrepancy has been conceptualized as the “awareness–uptake gap,” reflecting multi-level barriers beyond individual knowledge. Purpose: This integrative review aimed to compare PrEP awareness, acceptance, and utilization among MSM populations in South Korea and international settings, and to identify structural, institutional, and psychosocial determinants contributing to the awaness, uptake gap. The study further sought to derive practical implications for nursing practice and health policy. Methods: An integrative literature review was conducted following Whittemore and Knafl’s five-step methodology and reported in line with PRISMA guidance. Electronic searches were performed in PubMed, Google Scholar, RISS, ScienceON, and DBpia for peer-reviewed studies published between 2015 and 2025 in English or Korean. The final search was completed on 31 January 2026. A total of 5952 records were identified, and 187 studies met the inclusion criteria after screening and duplicate removal. Quality appraisal was conducted using AXIS, Newcastle-Ottawa Scale, RoB 2.0, CASP, and MMAT according to study design, and the findings were synthesized within an environmental–structural–individual framework. Results: The included studies consistently showed that awareness of PrEP exceeded actual uptake. Across settings, the awareness–uptake gap was shaped by policy environment, service accessibility, stigma, privacy concerns, economic burden, institutional complexity, and provider preparedness. Comparative evidence from China, Thailand, Belgium and France, Brazil, and West Africa further suggested that awareness alone did not ensure uptake when service pathways were fragmented, culturally unsafe, or poorly understood. Conclusions: Closing the awareness–uptake gap requires integrated policy and practice strategies that extend beyond cost reduction. Strengthening confidentiality systems, simplifying service pathways, and enhancing provider competency—particularly through nurse-centered PrEP navigation and counseling models—may support more sustainable PrEP expansion among MSM populations in global settings. Full article
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19 pages, 4256 KB  
Article
Efficient Production of 2-Keto-l-Gulonic Acid via One-Step Fermentation Using Gluconobacter oxydans WTF0512 and Ketogulonicigenium vulgare WTF0114
by Hongling Liu, Xiangxin Bu, Mingxia Jiao, Wenhu Chen, Xiangling Jiang, Haibo Yuan, Di Huang, Yi Jiang, Cheng Zhong and Tengfei Wang
Microorganisms 2026, 14(5), 947; https://doi.org/10.3390/microorganisms14050947 - 22 Apr 2026
Viewed by 90
Abstract
Currently, the main method for producing the vitamin C precursor 2-keto-l-gulonic acid (2-KLG) is a two-step fermentation process, in which secondary sterilization and fermentation processes result in higher costs and energy consumption. Consequently, the development of a one-step fermentation process is seen as [...] Read more.
Currently, the main method for producing the vitamin C precursor 2-keto-l-gulonic acid (2-KLG) is a two-step fermentation process, in which secondary sterilization and fermentation processes result in higher costs and energy consumption. Consequently, the development of a one-step fermentation process is seen as a more desirable approach for 2-KLG production. In this study, we used Gluconobacter oxydans WTF0512 and Ketogulonicigenium vulgare WTF0114 as co-cultured strains for the production of 2-KLG from d-sorbitol via one-step fermentation. The fermentation behaviors of G. oxydans WTF0512 and K. vulgare WTF0114 were initially investigated. Subsequently, the fermentation process and medium were optimized, and the titer of 2-KLG reached 132.99 ± 0.52 g/L, with a molar conversion rate of 92.42%, which, to the best of our knowledge, is the highest production via one-step fermentation reported to date. These findings will provide a basis for developing a more economical large-scale one-step fermentation process for the production of 2-KLG. Full article
(This article belongs to the Section Microbial Biotechnology)
17 pages, 468 KB  
Article
Proximity-Based Digital Practices in Fashion—Ateliers of Social Integration as Relational Infrastructures of Care and Innovation
by Cecilia Manzo, Silvia Mazzucotelli Salice and Michele Varini
Societies 2026, 16(5), 135; https://doi.org/10.3390/soc16050135 - 22 Apr 2026
Viewed by 79
Abstract
This article advances a critical rethinking of digital transformation in craft-based and socially embedded production systems by examining ateliers of social integration as community-led solidarity spaces where sewing and embroidery practices intersect with relational, care-oriented, and collective dimensions. Existing debates on digitalisation [...] Read more.
This article advances a critical rethinking of digital transformation in craft-based and socially embedded production systems by examining ateliers of social integration as community-led solidarity spaces where sewing and embroidery practices intersect with relational, care-oriented, and collective dimensions. Existing debates on digitalisation remain largely centred on automation, scale, and efficiency, overlooking how technology operates within care-based and territorially embedded economies. To address this gap, the article develops an alternative analytical framework grounded in relational economies and the ethics of care. While the phenomenon is transnational, the empirical analysis focuses on the Italian context and draws on data from CreAbility, an ongoing action-research project aimed at building a digital community of micro and small fashion enterprises, associations, and designers characterized by social and cultural impact. Against dominant, scale-oriented models of innovation, the article conceptualises ateliers of social integration as relational ecosystems in which value is co-produced through social ties, inclusion practices, and localized knowledge. From this perspective, digital technologies serve as situated mediators that extend and amplify proximity-based relations. This reframing challenges linear and growth-centred accounts of digital innovation, instead proposing a non-linear, care-centred, and place-based model of digital transformation. Methodologically, the study adopts a mixed-methods design combining quantitative and qualitative techniques. Data were collected between June and July 2025 through an online questionnaire distributed to a broader population of Italian ateliers of social integration and were complemented by participatory focus groups involving organisational representatives. The findings show that these ateliers operate as infrastructures of proximity in which production, care, and community are co-constitutive, and where digital practices support forms of extended embeddedness rather than substitution. In doing so, the article contributes to debates on digitalisation, social innovation, and the care economy by showing how alternative, relational, and non-scalable models of production can reshape the meaning and the trajectories of innovation. Full article
19 pages, 956 KB  
Article
Evaluation of Parental Knowledge and Practices in Pediatric Fever Management Among Iranian Families: A Cross-Sectional Study
by Tarlan Soumei, Sara Hamideh Kerdar, David D. Martin, Parviz Rafiezadeh and Ekkehart Jenetzky
Pediatr. Rep. 2026, 18(3), 61; https://doi.org/10.3390/pediatric18030061 - 22 Apr 2026
Viewed by 85
Abstract
Background/Objectives: Fever is a common concern among parents, often leading to heightened anxiety and misconceptions about its management. While fever phobia has been extensively studied in Western countries, data from the Middle East—particularly Iran—remain limited. Understanding parental knowledge and anxiety in this [...] Read more.
Background/Objectives: Fever is a common concern among parents, often leading to heightened anxiety and misconceptions about its management. While fever phobia has been extensively studied in Western countries, data from the Middle East—particularly Iran—remain limited. Understanding parental knowledge and anxiety in this cultural context is essential for developing targeted educational interventions. This study aims to assess parental knowledge, behavior, and anxiety regarding fever in children and to identify factors associated with higher levels of anxiety among Iranian parents, thereby contributing culturally specific evidence to the international literature on pediatric fever management. Methods: A cross-sectional study was conducted involving 552 parents from Tehran, Iran, recruited through convenience sampling. Data were collected using self-administered questionnaires assessing demographic characteristics, knowledge about fever, treatment practices, and anxiety levels using a 10-point Likert scale. Principal component analysis (PCA) was performed to examine the underlying factors influencing parents’ decisions to reduce fever. Univariate and multivariate linear regression analyses on standardized z-values were conducted to determine the predictors of fever-related anxiety. Results: Results showed that 67.4% of parents experienced anxiety when managing their child’s fever, with 65.6% perceiving fever as harmful. Fear of febrile seizures (77.4%) and brain damage were significant concerns motivating parents to reduce fever. Female parental sex (β = 0.336, p = 0.004) and the perception of fever as harmful (β = 0.058, p < 0.001) were the strongest predictors of fever-related anxiety. The PCA identified two key factors influencing fever management behavior: well-being protection and medical risk prevention. Parents commonly treated fever using combinations with either Paracetamol or Ibuprofen (47.6%). Conclusions: Parental anxiety about fever in Iran is largely driven by misconceptions, especially regarding febrile seizures and brain damage. Culturally tailored education and clear communication from healthcare providers are essential to reduce these fears, improve fever management, and decrease unnecessary antipyretic use. Full article
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