Search Results (6,227)

To address the shortage of natural sand and the unclear mechanism of lithology’s influence on the application of manufactured sand, this study explores the applicability of neutral rock manufactured sand in asphalt mixtures. Taking neutral diabase manufactured sand as the research object, a series of tests including the Marshall test, water stability test, high- and low-temperature stability test, and surface free energy (SFE) test were conducted to systematically analyze the effects of aggregate lithology on the volumetric indicators, road performance, and interface adhesion of asphalt mixtures. Additionally, the improvement effect of cement as an anti-stripping agent was verified. The results show that lithology of manufactured sand significantly regulates the performance of asphalt mixtures. In terms of volumetric indicators, the limestone manufactured sand mixture has the smallest void ratio (3.81%), while the diabase manufactured sand mixture has the largest (5.81%), requiring an appropriate increase in the mixing ratio of diabase manufactured sand to optimize the compaction effect. For water stability, the short-term performance ranks as diabase ≈ limestone > granite, and the long-term durability ranks as limestone > diabase > granite. A least-squares linear regression model demonstrated that the polar component of aggregate surface free energy exhibits a strong positive correlation with asphalt–aggregate adhesion work (R² = 0.92), which quantitatively explains variations in the 48 h immersed Marshall residual stability ratio among different lithologies. Regarding high-temperature stability, the order is diabase > limestone > granite. Thanks to its low crushing value and strong angularity, the diabase manufactured sand mixture achieves a dynamic stability of 12,629 times/mm at 60 °C, showing the best rutting resistance. In terms of low-temperature performance, the diabase manufactured sand mixture exhibits the optimal initial crack resistance (maximum flexural strain of 2757 με) and long-term durability (strain attenuation rate of 11.7% after 30 cycles), while the granite manufactured sand mixture fails to meet the design requirements. Adding 1.5%~2.0% cement can significantly improve the adhesion between manufactured sand and asphalt, with more obvious enhancement effects on granite and diabase, thereby optimizing water stability and high-temperature stability. The research results provide theoretical support and technical reference for the scientific selection and engineering application of fine aggregates in asphalt pavements. Full article

Seasonal dietary shifts are associated with significant alterations in the gut microbiome of herbivores, yet the specific impacts of these shifts on microbial metabolic functions have not been fully elucidated. To address this gap, we employed DNA metabarcoding of fecal samples and 16S rRNA gene sequencing to explore the relationship between seasonal diet and gut microbiome composition in a population of sika deer (Cervus nippon kopschi). Our findings indicate pronounced seasonal variations in both dietary composition and gut microbial community structure. Notably, during the winter months, the gut microbiome exhibited a significant enrichment of predicted pathways (predicted using PICRUSt2) related to fatty acid and lipid biosynthesis and degradation, amino acid degradation, and the TCA cycle. Conversely, the active growing seasons (spring and summer) were characterized by enhanced glycolysis and amino acid biosynthesis pathways. These functional shifts showed significant correlations with seasonal changes in dietary nutrients, such as crude protein and fiber, and climatic factors. Our results suggest that seasonal dietary changes are associated with a restructuring of the gut microbiome’s metabolic potential, which may assist sika deer in adapting to fluctuating physiological demands and environmental challenges across different seasons. Full article

Volcanic lava has a complete primary succession; the plant community composition can explain a great part of the variation of soil microbial diversity and community structure. Bacteria dominate the soil microbial communities in abundance and diversity, and they are important drivers of organic matter decomposition and nutrient cycling. With 16S rRNA Illumina Miseq sequencing techniques, we analyzed the soil bacterial communities and diversities associated with different vegetation types in Wudalianchi. Shrub soils had the highest pH, MC, TOC, TN, AP, AN and NN, whereas moss soils had the lowest. The Shannon, Ace, and Pd indices of bacteria showed significant differences in the different vegetation types (p < 0.05). Bacterial Ace, Shannon, and Simpson indices peaked in Herb and Shrub is highest. The Proteobacteria, Actinobacteriota, Acidobacteriota, Planctomycetota and Chloroflexota were the most abundant groups at phyla level. Bacterial community composition varied significantly across vegetation types (p < 0.05). At the family level, Pseudonocardiaceae predominated in moss soils. Redundancy analysis and correlation analysis revealed MC, pH, and TP as key environmental factors shaping bacterial communities. Functional predictions based on taxonomic data indicated that chemoheterotrophy and aerobic chemoheterotrophy were the predominant functional groups. In conclusion, although soil microbial composition and diversity differed markedly across vegetation types following volcanic eruptions, functional groups prioritized carbon fixation strategies. Full article

Glutathione (GSH) is a central regulator of redox homeostasis, melanogenesis, and cellular repair, and has gained increasing attention in dermatology for its potential roles in skin brightening, anti-aging, and tissue regeneration. This systematic review evaluated molecular, clinical, and translational evidence of glutathione’s applications and safety across different delivery modalities. The review followed PRISMA guidelines and included studies published between 2000 and 2025. A total of 194 studies met the inclusion criteria, evaluating the effectiveness of glutathione in esthetic dermatology and regenerative medicine. Topical and oral glutathione demonstrated favorable effects on pigmentation, skin brightness, hydration, and oxidative stress markers. Injectable glutathione increases systemic levels rapidly, but is associated with short-lasting effects and potential safety concerns. Glutathione S-transferases facilitate the conjugation of glutathione to electrophilic xenobiotics, thereby protecting proteins and nucleic acids from electrophile-induced damage. Glutathione Peroxidase employs GSH as an electron donor to reduce hydrogen peroxide and lipid hydroperoxides, thus protecting membrane lipids, mitochondrial membranes, and DNA from oxidative damage. Glutathione facilitates the regeneration of other antioxidants, such as vitamin C and vitamin E, through redox cycling. A consistent correlation exists between reduced GSH levels and neuronal dysfunction. Elevated GSH levels enhance cellular resistance to oxidative stress and reduce apoptotic signaling. GSH plays a pivotal role in cutaneous aging and tissue repair through redox regulation, mitochondrial protection, and the modulation of inflammatory and extracellular matrix pathways. To elucidate the clinical significance of glutathione, future research should focus on conducting randomized controlled trials, developing standardized formulations, and performing long-term safety assessments. Full article

This study aims to elucidate the effects and mechanisms of ammonium (NH₄⁺-N) and nitrate (NO₃⁻-N) nitrogen on the efficiency of Salix linearistipularis K. S. Hao in remediating heavy metal-contaminated soils. Thus, the effects of 15 fertilization treatments (comprising three nitrogen levels and five nitrogen form ratios) on Pb and Cd accumulation, soil properties, microbial structure, and metabolic characteristics were investigated using a pot experiment. The results indicated that Pb and Cd accumulation were the highest under the L12 treatment (60 kg N·hm⁻²·year⁻¹, NH₄⁺-N/NO₃⁻-N = 1:2), whereas nitrate-only treatments, irrespective of concentration, resulted in a decrease in accumulation. In the L12 treatment, biomass increased by 87.0%, with Pb and Cd accumulation rising by 85.71% and 80.0%, respectively, suggesting that biomass may contribute predominantly to heavy metal accumulation. Additionally, NH₄⁺-N/NO₃⁻-N ratio had a greater effect on biomass than the nitrogen application amount. Microbial composition was altered, and the relative abundance of heavy metal-resistant microbes increased. However, the amount of nitrogen fertilizer had a stronger impact on microbial variation. Under different nitrogen application rates and NH₄⁺-N/NO₃⁻-N ratios, the formation or disappearance of unique metabolic pathways related to amino acids and carbohydrates was observed. Furthermore, both microbial metabolism and the bioavailability of Pb and Cd were positively correlated with nitrogen levels and NH₄⁺-N/NO₃⁻-N ratios. These findings indicate a potential association between shifts in microbial metabolism and the bioavailability of heavy metals. Therefore, the simultaneous application of ammonium and nitrate nitrogen in appropriate ratios can enhance the remediation efficiency of S. linearistipularis by boosting biomass and heavy metal bioavailability via microbial metabolism. The findings of this study not only provide novel insights into improving the phytoremediation efficiency of woody plants through fertilization strategies but also lay a theoretical foundation for the effects of nitrogen fertilization on nutrient cycling in metal-contaminated soils. Full article

In the transition toward the circular economy and high-rate manufacturing, thermoplastic composites (TPCs) are increasingly outperforming conventional thermosets due to their superior fracture toughness, recyclability, and rapid processing capabilities. Among available joining techniques, fusion bonding stands as the main mechanism for structural integration, as it bypasses the fundamental limitations of traditional assembly: the weight penalties and stress concentrations inherent in mechanical fastening, as well as the long cycle times and interfacial weaknesses often associated with adhesive bonding. This paper provides a comprehensive evaluation of welded TPC joints through a dual-methodological approach: a historical narrative review tracing the evolution of fusion bonding principles, and an in-depth literature review of 25 key articles published since 2015. The analysis focuses on the intersection of experimental characterization—quantifying interfacial strength and fracture energy—and numerical modeling techniques, such as Cohesive Zone Modeling (CZM) and progressive damage analysis. By categorizing recent advancements into specific thematic pillars, this study correlates process-induced phenomena with macro-scale mechanical performance and virtual predictive accuracy. The findings synthesize decades of foundational knowledge with cutting-edge research trends, highlighting the transition from empirical testing to computational design. This work serves as a roadmap for achieving standardized, high-performance thermoplastic assemblies in safety-critical applications. Full article

Following successful national forest restoration projects, South Korea has designated and operates Leading Forest Management Zones (LFMZs) to improve forest quality and promote sustainable use. The objective of this study is to comparatively evaluate the operational characteristics of 26 LFMZs (5 national and 21 private forests) based on complete long-term data from 2013 to 2024 and to identify ownership-based structural differences in integrated forest management performance. Five core indicators representing the forest management cycle (afforestation, timber harvest, forest products, forest roads, and forest tending) were analyzed using multivariate statistical methods. Permutational Multivariate Analysis of Variance (PERMANOVA) results revealed statistically significant structural differences between national and private forest management systems (F = 13.22, p = 0.001, R² = 0.47). Non-metric multidimensional scaling (NMDS) identified forest road development and timber harvest intensity as the primary drivers of these differences. National forest LFMZs exhibited consistently higher and more balanced management intensity across all indicators, supported by stable institutional frameworks and professional management capacity. In contrast, private forest LFMZs showed substantial variability in performance, reflecting differences in ownership structure and regional conditions. Correlation analysis further demonstrated strong positive relationships among afforestation, forest tending, forest road development, and timber harvest, underscoring the importance of integrated forest management. These findings provide empirical evidence to support differentiated, ownership-sensitive forest management strategies and contribute to strengthening sustainable forest governance in South Korea under climate change and socio-economic transitions. Full article

RNA editing is a critical post-transcriptional modification that contributes to transcriptomic and proteomic diversity. The most common A-to-I (recognized as G) RNA editing enzymes are adenosine deaminases acting on RNA 1 and 2 (ADAR1 and ADAR2, respectively), which mediate alterations across all regions of mRNA molecules. However, a systematic cross-tissue view of RNA editing and its molecular correlates is still lacking. Here, we developed a rapid method for ADAR editing assessment based on 24 frequently edited positions in coding regions, which enables faster estimation of RNA editing levels than previous methods. We applied this metric to assess RNA editing in normal and cancerous lung and colorectal tissues. We analyzed RNA and whole exome sequencing profiles of experimental 172 colorectal and 144 lung cancer samples, and literature 646 colorectal and 1037 lung cancer samples. We also examined two types of control tissues: tumor-matched normal tissues (51 colorectal and 108 lung samples) and healthy tissues (6 colorectal and 7 lung samples). Overall ADAR-mediated RNA editing levels were ~2.9- and ~4.7-fold higher in healthy controls than in colorectal and lung cancers, respectively. In addition to their well-known association with immune cells, we identified positive correlations of ADAR editing with 740 molecular pathways including those responsible for extracellular matrix organization, RAS-MAPK axis and G2/M phase cell cycle arrest, and negative—with 139 pathways responsible for DNA repair, apoptosis, expression of transposable elements, and other factors. Full article

Fat deposition plays a crucial role in regulating the production performance and meat quality of broilers. Although the heterogeneity of mammalian adipocytes has been extensively studied, research on the molecular mechanisms underlying differences in lipid droplet accumulation in avian adipocytes remains limited. This study confirmed a significant positive correlation (R² > 0.81, p < 0.001) between the SSC signal and lipid droplet content via fluorescence staining of lipid droplets, Oil Red O staining, and triglyceride (TG) quantification. Based on this, a label-free sorting strategy using SSC signals was established to sort differentiated chicken preadipocytes, obtaining high lipid droplet (H) and low lipid droplet (L) subpopulations, which were subsequently subjected to transcriptome sequencing and differential gene expression (DEG) analysis, followed by GO and KEGG enrichment analysis. The results indicated no significant differences in the expression of adipogenesis marker genes (PPARG, LPL, CD36, PLIN1, PLIN2) between the high lipid droplet (H) and low lipid droplet (L) groups, suggesting that both groups are at similar stages of differentiation. KEGG analysis revealed that both the H vs. NC and L vs. NC comparisons were enriched in common pathways, including the PPAR signaling pathway, ECM–receptor interaction, focal adhesion, cytokine–receptor interaction, and calcium–Apelin signaling pathway, suggesting that both groups of cells had activated the adipogenesis program. GO analysis showed that, in both H vs. NC and L vs. NC comparisons, differentially expressed genes (DEGs) were enriched in biological processes (BPs) related to cell adhesion, nucleosome assembly, chromatin remodeling, and receptor activity, as well as cellular components (CCs) such as the extracellular matrix, cytoskeleton, and nucleosome organization, indicating extensive gene reprogramming and activation of signaling transduction during differentiation. In the H vs. L comparison, enriched pathways included ABC transporters, ECM–receptor interaction, focal adhesion, gap junctions, microtubule-related processes, and neuroactive ligand–receptor interactions, involving lipid transmembrane transport, cytoskeleton stabilization, and signal transduction regulation, suggesting that high lipid droplet cells are more mature in lipid droplet transport, storage, and homeostasis maintenance. GO enrichment results further supported this conclusion, as H vs. L specifically enriched processes related to microtubule-related processes, cell cycle, and redox reactions (BPs), as well as chromosome organization, cytoskeleton, and motor activity (CC/MF), indicating that high lipid droplet cells maintain lipid droplet fusion and metabolic homeostasis via enhanced microtubule transport and antioxidant regulation. Differential gene analysis revealed that the L group upregulated genes associated with fatty acid synthesis and elongation (ACACA, FASN, SCD, FADS2, ELOVL1), cholesterol and isoprenoid biosynthesis (HMGCR, SQLE, MSMO1, DHCR7, DHCR24, FDPS, LSS), and fatty acid oxidation (PPARA, PPARD, ACAD11, SIRT5), reflecting a metabolic characteristic of concurrent lipid synthesis and mobilization; the H group, conversely, upregulated genes associated with lipid droplet formation and storage (G0S2, MOGAT1, GPAT4, PLIN4, AUP1), lipid transport (ABCA1, ABCA2, ABCG1, OSBPL3, VLDLR), and antioxidant defense (GPX3, GPX4, HMOX1), exhibiting a storage and homeostasis-oriented metabolic state. In the NC, L, and H groups, the expression of five genes—GEM, SPP1, ABCA1, PDLIM3, and ITGA8—showed a gradual increase, suggesting that these genes were associated with preadipocyte differentiation and lipid droplet deposition. In summary, although the high and low lipid droplet subpopulations of chicken preadipocytes exhibit similar differentiation states, they form distinct metabolic orientations. The L group is characterized by active lipid synthesis, fatty acid oxidation, and membrane lipid remodeling, while the H group predominantly features lipid droplet storage, lipid transport, and antioxidant homeostasis. This study highlights the molecular mechanisms underlying the metabolic heterogeneity of avian adipocytes and provides a theoretical basis for poultry fat deposition regulation and genetic improvement. Full article

Urban wetlands are assumed to contribute to nitrous oxide (N₂O) emissions; however, the microbial mechanisms underlying enhanced N₂O fluxes in urban wetlands and differences in microbial responses between aquatic and soil compartments have not been clearly identified. Here, we characterized the nitrogen (N) cycling microbial communities and their functional metabolic pathways in urban and rural wetlands using metagenomics and N₂O flux measurements. Results showed that urbanization drove a 6~8-fold increase in N₂O fluxes from urban wetlands compared to rural wetlands. Structural equation modeling (SEM) confirmed that urbanization intensity was a primary driver (standardized coefficients: 0.72 for soil and 0.92 for water). In wetland water, N₂O emissions were negatively correlated with inorganic nutrient concentrations (coefficient = −0.62). Aquatic microbial communities exhibited substantial taxonomic shifts but preserved network connectivity, indicating adaptive strategies for surviving urban perturbations at the cost of reduced functional redundancy. In wetland soil, microbial communities maintained stability under urbanization, which was attributed to environmental buffering from heterogeneous microenvironments. Soil N₂O emissions were positively linked to microbial alpha diversity (coefficient = 0.79). Furthermore, urban wetlands enriched genes mediating nitrification and denitrification while depleting genes associated with N fixation and organic N metabolism. This functional shift reflects microbial specialization in processing elevated reactive N (Nr) inputs from urban sources, trapping urban wetlands in an “N loss loop” that reinforces high N₂O fluxes. This study elucidates the microbial mechanisms governing wetland N₂O emissions under urbanization, thereby enhancing understanding of microbially mediated N cycling in the urban wetland ecosystem. Full article

The physiological impact of neoadjuvant therapy on vascular and thermal responses in breast cancer patients remains poorly understood, despite its clinical relevance for predicting treatment outcomes and managing therapy-related side effects. Sensor-based monitoring technologies, such as thermography and Doppler ultrasound, provide non-invasive approaches to assess circulatory and thermal changes, potentially serving as predictive biomarkers of therapeutic efficacy. This study aimed to evaluate vascular impairment and correlate circulatory alterations with skin surface temperature in women undergoing neoadjuvant therapy for breast cancer. A total of 38 women were enrolled and distributed into two groups: patients receiving eight cycles of neoadjuvant chemotherapy and healthy controls. Thermographic imaging was employed to measure upper-limb surface temperature, while Doppler ultrasound assessed arterial and venous blood flow in the cubital fossa. Paired Student’s t-tests compared experimental moments (C1, C5, C8), with normality assessed from difference scores (Δ) and results expressed as mean differences with 95% CIs (p < 0.05, two-tailed). Associations between surface temperature and arterial blood flow were examined using simple linear regression (R², F-statistic, β, p-values). Analyses were performed in SPSS 20.0 (SPSS Inc., Chicago, IL, USA). Significant increases in surface temperature (p < 0.001) and blood flow velocity (p < 0.004) were observed in patients compared with controls prior to therapy, suggesting pre-existing vascular and thermal dysregulation. Neoadjuvant therapy significantly altered thermal and vascular dynamics, reinforcing the utility of sensor-based monitoring to capture subtle physiological responses during treatment. Full article

Glaciers in the Canadian Arctic Archipelago (CAA) contribute significantly to sea-level rise, yet sparse in situ data limit regional climate assessments. This study presents the first decadal (2013–2024) satellite-derived time series of late-summer snowline altitude (SLA) for six CAA glaciers, utilising 9920 Landsat 8/9 and Sentinel-2 scenes. Glacier surface cover types (snow and bare ice) were mapped via machine learning, and SLA was extracted using elevation-binning and Snow-Elevation Histogram Analysis (SEHA). Elevation data were obtained from ArcticDEM v3; positive degree days (PDD) from Eureka, Pond Inlet, and Pangnirtung were used to characterize melt-season forcing. Satellite-derived SLA was validated against equilibrium-line altitude (ELA) observations from White Glacier. All glaciers exhibit a characteristic seasonal SCA cycle: maximum extent in June, minimum in August, and partial recovery in September, with extreme anomalies in 2020. Annual peak SLA correlates positively with summer warmth; sensitivities to PDD were 2.56, 0.67, and 0.83 m (°C d)⁻¹ for White, Highway, and Turner glaciers, respectively. Hypsometry strongly modulates climatic sensitivity: glaciers with limited high-elevation area (e.g., BylotD20s, Turner) frequently lose their accumulation zones in warm years. At White Glacier, SLA replicates interannual ELA variability with high correlation and lower error using the elevation-bin method (mean bias +53 m; RMSE 177 m) compared with SEHA (+165 m; 339 m). Meteorological records indicate significant summer and winter warming at Eureka, with increasing PDD; precipitation trends are spatially variable. A regionally calibrated, quality-assured elevation-bin method produces objective and transferable SLA time series, suitable for ELA estimation in data-sparse Arctic settings. The SLA–PDD relationship and hypsometry-dependent responses highlight increasing stress on accumulation zones under continued warming. Reporting SLA uncertainty and image quality, alongside expanded field observations, will enhance Arctic-wide glacier monitoring. Full article

Background/Objectives: Demineralization around orthodontic brackets may compromise enamel integrity and alter the mechanical stability of the bracket–adhesive–enamel interface, thereby influencing bond performance and clinical outcomes. This study aimed to evaluate the effect of enamel demineralization on the fatigue-based shear bond strength (SBS) of different orthodontic brackets. Methods: Seventy-five extracted maxillary premolars subjected to demineralization were allocated into five groups (n = 15 per group). Victory metal (Group 1), APC Clarity Advanced ceramic (Group 2), Clarity Self-ligating ceramic (Group 3), Gemini metal (Group 4), and Clarity Advanced ceramic (Group 5) brackets were bonded to the tooth surfaces using Transbond XT (3M Unitek, Monrovia, CA, USA). The mean demineralization values of the specimens were recorded before demineralization (T0) and after exposure to an artificial cariogenic environment (T1). Fatigue-based SBS was evaluated under cyclic loading (10 N, 0.5 Hz) at a crosshead speed of 300 mm/min using a closed-loop controlled, low-cycle fatigue testing machine and expressed as the number of shear strokes to failure. The level of statistical significance was set at p < 0.05. Results: No significant differences in demineralization were observed among the groups at T0 (p > 0.05); however, all groups showed significant increases at T1 (p < 0.05), with Group 1 demonstrating significantly lower demineralization than the other groups (p < 0.05). Fatigue-based SBS was higher in Groups 1, 3, and 5 than in Groups 2 and 4, as indicated by a greater number of shear strokes to failure (p < 0.05). In Groups 2 and 4, a statistically significant negative correlation was observed between changes in enamel demineralization and the number of shear strokes to failure (p < 0.05). No hard tissue damage was observed in Group 5 during fatigue testing. Conclusions: Increased demineralization may adversely affect fatigue-based SBS and increase the risk of hard tissue damage. Under plaque-related demineralization conditions, Victory metal and Clarity Advanced ceramic brackets may demonstrate more favorable fatigue bond behavior; however, further in vitro and in vivo studies are required to confirm these findings. Full article

This LCA study addresses the research gap concerning the comprehensive environmental implications of using paving block aggregates (PBA), derived from crushed waste concrete paving blocks (CPB), as a sustainable replacement for natural aggregates in cementitious materials. While the concrete industry faces twin challenges—high CO₂ emissions from cement and the massive ecological toll of extracting 20 Gt/year of natural aggregates—a systematic life cycle assessment of this specific waste stream was necessary, especially one that considered potential material interaction trade-offs. The study’s conclusions offer critical insight into achieving genuine sustainability. Consistently, cement production was identified as the overwhelming environmental hotspot, contributing over 90% of the global warming potential (GWP) across all scenarios. This finding indicates that even substantial changes in aggregate sourcing can only deliver limited GWP reductions unless accompanied by strategies targeting cement-related emissions. While substituting natural aggregates with PBA generally provided environmental benefits, a crucial trade-off was identified: the significantly higher dosage of superplasticizer required to maintain the workability of the PBA mixes. For mortar, the burden from the increased plasticizer became a major secondary hotspot, occasionally offsetting the gains from aggregate replacement. In these scenarios, the contribution of admixtures to the total GWP was sufficiently high to reduce or negate the environmental benefits achieved through aggregate substitution. In contrast, aggregate replacement proved more favorable in concrete than in mortar, as the concrete scenarios showed a weaker correlation between environmental impact and plasticizer use. The authors conclude that future strategies must prioritize reducing cement content and, critically, systematically consider the necessary use of admixtures to ensure that the intended environmental improvements are genuine and not counteracted by the side effects of material substitution. The quantified LCA results demonstrate that cement reduction offers the highest mitigation potential, while admixture optimization is essential to prevent secondary environmental hotspots, particularly in mortar applications. Full article

As climate change increasingly impacts the water cycle across the Alpine region, monitoring surface soil moisture is essential for hydrological models and drought early warning. Yet operational products either mask steep terrain, or lack the spatial resolution to capture the surface soil moisture (SSM) spatial variability of the Alpine catchments. This study presents a novel retrieval approach aggregating Sentinel-1 radiometric terrain-corrected backscatter (${\gamma }^0$) into 100 m elevation bands per sub-basin and aspect across the Austrian Alps. The resulting Alpine backscatter product is processed through an orbit-wise change detection to derive over 34,000 SSM timeseries, evaluated using ERA5-Land and compared to 264 precipitation stations from Geosphere for the period from 2016 to 2024. The results show satisfactory agreement with ERA5-Land (Pearson correlation > 0.46 below 400 m) and capture in situ precipitation-driven anomalies with the strongest performance below 400 m (Spearman correlation > 0.47), particularly over grasslands and south-facing slopes. Despite its limitations at high elevation and over dense vegetation, Sentinel-1 provides consistent and elevation-stratified information across more than 80% of the Austrian Alps, typically excluded from operational products. The new Alpine SSM product highlights Sentinel-1’s potential to support hydrological modeling, drought monitoring, and water resource management across complex topography such as the Alps. Full article