Search Results (146)

Forests are considered one of the most valuable natural areas in metropolitan region landscapes. Considering the sensitivity and ecosystem services provided by trees, the definition of urban forest ecosystems is nowadays based on a comprehensive understanding of the entire urban ecosystem. The effective capturing of particulate matter is one of the ecosystem services provided by urban forests. These ecosystems function as efficient biological filters. Plants accumulate pollutants passively via their leaves. Therefore, another ecosystem service provided by city forests could be the use of tree organs as bioindicators of pollution. This paper aims to estimate differences in trace metal pollution between the wooded urban areas of Vienna and Krakow using leaves of evergreen and deciduous trees as biomonitors. An additional objective of the research was to assess the ability of the applied tree species to act as biomonitors. Plant samples of five species—Norway spruce, Scots pine, European larch, common white birch, and common beech—were collected within both areas, in seven locations: four in the “Wienerwald” Vienna forest (Austria) and three in the “Las Wolski” forest in Krakow (Poland). Concentrations of Cr, Cu, Cd, Pb, and Zn in plant material were determined. Biomonitoring studies with deciduous and coniferous tree leaves showed statistically higher heavy metal contamination in the “Las Wolski” forest compared to the “Wienerwald” forest. Based on the conducted analyses and the literature study, it can be concluded that among the analyzed tree species, only two: European beech and common white birch can be considered potential indicators in environmental studies. These species appear to be suitable bioindicators, as both are widespread in urban woodlands of Central Europe and have shown the highest accumulation levels of trace metals. Full article

Purpose: Standard automated perimetry (SAP) remains the gold standard functional test in glaucoma, used primarily for evaluating peripheral vision loss. Central contrast sensitivity (CCS) has emerged as a potential early functional marker of glaucomatous damage. This systematic review aimed to describe the different methods used to measure CCS in randomized controlled trials (RCT) involving glaucoma patients. Methods: We searched the MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials, Epistemonikos, and ClinicalTrials.gov databases on 25 January 2023, and updated the search on 12 February 2025. Eligible studies comprised RCTs that reported CCS as an outcome in patients with glaucoma, suspected glaucoma, or ocular hypertension. No restrictions were placed on age, sex, ethnicity, geography, intervention, or publication year. Abstracts and full texts were screened independently by two reviewers. Descriptive statistics were used. No formal risk of bias assessment was performed, due to the descriptive nature of the review. Results: Of 1066 records screened, 31 studies met the eligibility criteria. The study sample size ranged from 7 to 207 (median: 23), with most studies involving primary open-angle glaucoma. Interventions were diverse, mainly involving topical medications, with timolol being the most frequent. Eleven CCS test methods were identified. Five studies did not report the method used. The CSV-1000 was the most commonly used test, being applied in 11 studies. Conclusions: CCS has been measured using a wide range of methods in glaucoma RCTs, with limited standardization. Most of the included studies were small, variably reported, and conducted over 10 years ago, suggesting a decreasing interest in CCS as an outcome measure in glaucoma RCTs. Funding: This review was funded by Oslo University Hospital and the Research Council of Norway. Registration: This review was registered on the OSF. Full article

In the context of accelerated digitization and the transition to sustainability, this study explores the relationship between the use of cloud computing services and greenhouse gas (GHG) emissions in the IT and communications sectors at the European level using panel data provided by Eurostat for the period 2014–2021. The initial set included 14 countries, but due to incomplete data, the final analysis was performed on a consistent and complete dataset comprising 8 countries: Bulgaria, Cyprus, Denmark, Hungary, Latvia, Norway, Poland, and Romania. The applied methodology includes VAR and VECM econometric models, the Granger causality test, impulse response functions, and variance decomposition. The results show a long-term cointegrating relationship between the variables, highlighting the existence of mass and energy transfer to centralized infrastructures such as data centers. The IT subsectors (J62_J63) demonstrate superior efficiency in reducing GHG emissions compared to the general communications sector (J), highlighting the positive impact of a high level of digitization. Although the research provides valuable insights into the relationship between digitization and sustainability, a major limitation is that not all EU countries are represented. This study provides actionable policy recommendations to minimize the ecological impact of digital technologies and enhance resource efficiency in the green transition era. Full article

Background: Knowledge discovery in databases (KDD) can contribute to translational research, also known as translational medicine, by bridging the gap between in vitro and in vivo studies, and clinical applications. Here, we propose a ‘systems modeling’ workflow for KDD. Methods: This framework includes the data collection of a composition model (various research models), processing model (proteomics) and analytical model (bioinformatics, artificial intelligence/machine leaning and pattern evaluation), knowledge presentation, and feedback loops for hypothesis generation and validation. We applied this workflow to study pancreatic ductal adenocarcinoma (PDAC). Results: We identified the common proteins between human PDAC and various research models in vitro (cells, spheroids and organoids) and in vivo (mouse mice). Accordingly, we hypothesized potential translational targets on hub proteins and the related signaling pathways, PDAC-specific proteins and signature pathways, and high topological proteins. Conclusions: This systems modeling workflow can be a valuable method for KDD, facilitating knowledge discovery in translational targets in general, and in particular to PADA in this case. Full article

Forest ecosystems are crucial for terrestrial ecosystem stability, particularly in carbon sequestration, nutrient cycling, and water conservation. With climate change exacerbating, understanding changes in suitable habitats for the main European tree taxa [Norway spruce (Picea abies), pedunculate oak (Quercus robur), and European beech (Fagus sylvatica)] and their drivers is critical for forest conservation in Europe. Here, we analyzed the factors driving the tree taxa distribution and suitable habitats under the current and two future scenarios, namely, optimistic and pessimistic. Based on a species distribution model, climatic, land use, and topographic factors were introduced as variables. This study determined that the main factors driving the tree taxa distributions were temperature, followed by land use. Under the future optimistic scenario, the suitable habitats change for the three tree taxa. Suitable habitats emerge in high-latitude regions and the northern Mediterranean. Meanwhile, suitable habitats are decreasing in Central Europe. Under the pessimistic scenario, more significant changes occurred in these regions. The total suitable habitat area for the three tree taxa did not change consistently under both scenarios. The suitable habitat area for Norway spruce increased, whereas that for pedunculate oak decreased. However, both regions with increasing or decreasing suitable habitats face the potential for forest succession, which will also affect the stability of forest ecosystem functions and should be a key focus. Full article

The rapid adoption of smart technologies is increasingly evident in both personal and business contexts. The ‘post-pandemic’ economic recovery of 2022 and 2023 coincided with a global energy supply shortage driven by heightened energy demand and supply chain disruptions stemming from the ongoing Russian-Ukrainian conflict. The implementation of smart metering systems is a central component of European policies aimed at enhancing the competitiveness and environmental sustainability of energy markets. However, limited research exists on the acceptance of Smart Meter Technology (SMT) in general, specifically in Norway, as compared to other nations. SMT devices offer the potential for real-time energy consumption monitoring, enabling users to track and modify their usage patterns for optimized consumption. This study employs a mixed-methods research design to gather insights from both SMT consumers and vendors. Findings underscore the pivotal roles of familiarity, cost, social influence, and perceived usefulness in shaping consumer adoption of SMT. This article provides critical insights and implications for researchers, network operators, electricity companies, and government agencies. Full article

This article explores the process of developing policy briefs (PB) as strategic tools to translate knowledge stemming from the analysis of local educational practices into inclusive European policy recommendations. This paper highlights how educational practices from eleven partner institutions across Denmark, Norway, Poland, Portugal, and Spain informed recommendations to prevent early leaving from education and training (ELET) and to enhance youth’s school engagement. Educational practices involved a collaborative dialogue among multi-stakeholders to establish a shared vision about educational inclusion, and the co-creation of educational practices supported by monitoring, evidence collection, and the identification of promising examples. These elements reflect the aim to embed educational inclusion in policy development, while underscoring the role of PBs as mechanisms of participatory knowledge transfer between countries and sectors, bringing together diverse voices from policymakers, educators, researchers, and young people. In doing so, the methodological approach to produce PB recognised local produced knowledge as a catalyst for informed decisions promoting quality education. The analysis of PB highlights elements of the identified educational practices addressing ELET challenges, such as (i) implementing co-creation methodologies in both educational contexts and political formulation; (ii) addressing student citizenship as central to meaningful learning; (iii) valuing cross-sector partnerships to address systemic challenges, and (iv) reinforce relational pedagogies that enhance student–teacher and student–student relationships. Full article

This study evaluates the potential of various hardwood combinations in plywood production in response to increasing wood demand and a changing roundwood supply in Central Europe. Six different combinations of nine-layer plywood were produced using 2 mm rotary-cut veneers from lime (Tilia spp.), Norway maple (Acer platanoides), European hornbeam (Carpinus betulus), Sycamore maple (Acer pseudoplatanus), mountain ash (Sorbus aucuparia), and European beech (Fagus sylvatica) with phenol–formaldehyde adhesive, and they were compared to silver birch (Betula pendula) plywood as a reference. The raw densities of the test panels varied between 0.85 and 1.04 times the reference density (795 kg m⁻³). Flexural strengths (the modulus of rupture, MOR) ranged from 68 N mm⁻² to 104 N mm⁻² for a parallel fibre orientation and 44 N mm⁻² to 61 N mm⁻² for a perpendicular fibre orientation of the top layers. The modulus of elasticity (MOE) ranged from 7160 N mm⁻² to 11,737 N mm⁻² for the parallel fibre orientation and from 4366 N mm⁻² to 5575 N mm⁻² for the perpendicular orientation. The tensile shear strength varied between 0.91 and 1.69 times the reference (1.49 N mm⁻²). The thickness swelling after 24 h was higher in all variants than the reference (6.4%), with factors between 1.39 and 1.64. A significant effect was observed when layers with a lower density were arranged on the outside and those with a higher density in the core, resulting in a more uniform density distribution across the cross-section after hot pressing. This created a levelling effect on mechanical and physical properties, especially the modulus of rupture (MOR) and the modulus of elasticity (MOE). Overall, the evaluated hardwood combinations demonstrated comparable properties to the birch reference and industrially produced birch plywood. Full article

Conflicts between owners and contractors in state-led infrastructure and building projects pose significant challenges to project efficiency, cost control, and stakeholder collaboration. The aim of this study is to identify the primary causes of such conflicts in Norway and evaluate potential mitigation strategies. Deficiencies in tender documentation, unclear risk allocation, and limited early contractor involvement significantly contribute to project disputes considered as central facts. Using a mixed-methods approach, the research integrates survey data from 57 industry professionals and in-depth interviews with senior project managers. Statistical analysis results show that most people believe flawed tender documents and unclear risk sharing are big causes of conflicts. Specifically, 78% said tender documents were a problem, and 65% pointed to unclear risk allocation. Additionally, interviews revealed that involving contractors early in the process helps avoid misunderstandings and encourages better teamwork. The findings indicate sector-specific differences, with infrastructure projects primarily affected by technical ambiguities and contractual disputes, whereas building projects face more scope modifications and interpersonal conflicts. To mitigate these issues, the study recommends improving tender document quality, adopting collaborative contracting models, and increasing early contractor engagement. These measures can enhance project outcomes, reduce societal costs, and foster more efficient stakeholder collaboration in state-led construction initiatives. Full article

Reducing the energy consumption of the existing building stock is of paramount importance in the race to reach national and international climate goals. While multiple initiatives are in place and provide guidance, heritage-protected buildings are often not part of the equation. Protected buildings make up a large share of the existing building stock and therefore offer large savings potential. In Trondheim, Norway, alone, that share is close to 10%, which demands the establishment of representative retrofitting cases. A case study of the central buildings on the NTNU campus was established to specifically test passive retrofitting measures, which are greatly affected by heritage protection. The application of measures selected in collaboration with heritage authorities led to overall energy savings of 16% to 18%, while the energy for heating alone was reduced by 34% to 40%. The reductions were especially prominent during cold winter months, where overall consumption peaks were reduced by up to 37%, greatly decreasing the dependence on cold outdoor temperatures. The results make a case for the application of passive retrofitting measures to heritage-protected buildings despite them not reaching deep energy retrofitting goals, especially in cold climates and alongside other energy-saving or -producing measures. Full article

Tick-borne encephalitis virus (TBEV) is an emerging pathogen that initially causes flu-like symptoms and can progress to central nervous system (CNS) infections. Tick-borne encephalitis (TBE) is an endemic disease in southern coastal counties with regular human cases, while the causative agent, TBEV, is prevalent in ticks in most of the coastal regions of Norway. This study was aimed to understand TBEV infection status across Norway including both TBE endemic and non-endemic areas. For this, we analyzed a total of 1940 residual serum samples from 19 counties of Norway (as of 2016). The samples were initially screened by ELISA, followed by virus neutralization tests for TBEV confirmation. We found a similar TBEV seroprevalence of 1.7% in TBE endemic and 1.6% in non-endemic areas. Since TBE cases are only reported from endemic regions, our findings suggest a potential subclinical or asymptomatic infection and underdiagnosis in non-endemic areas. Notably, only 43% of the ELISA-positive samples were confirmed by virus neutralization tests indicating that not all ELISA positives are true TBEV infections. Additionally, 137 samples of patients presenting with symptoms of CNS infections from a non-endemic area were included. Of these samples, 11 ELISA-positive samples were analyzed for cross-reactivity among flaviviruses. Cross-reactivity was detected with Dengue virus, West Nile Virus, and non-specific reactions. This underscores the importance of using multiple diagnostic tests to confirm TBEV infections. None of the patients with CNS infection was found to be TBE positive, and in the whole cohort, we found a low TBEV seroprevalence of 0.7%. Full article

According to Norway’s Core Curriculum all students are to learn about Sámi issues, and the subject of mathematics is not exempt from it. Central to the Sámi tradition is non-standardized individual body-based measuring. Two Sámi pre-service teachers taught Sámi traditional measuring in an urban school where most students are non-Sámi. Their idea was for students to experience the usefulness of using their own bodies as measuring tools. Afterwards, a teacher educator interviewed the pre-service teachers about their experiences. The teaching unit was planned as if it were to be taught in a Sámi school, except that the language of instruction was Norwegian. Analysis shows how the teaching unit aligns with the suggestions and recommendations of Norway’s Truth and Reconciliation Commission. Analysis with respect to the Theory of Didactical Situations framework, TDS, which has not been developed for Indigenous education, show that TDS contributes to improving the teaching unit’s plan. We recommend that Sámi traditional measuring should be taught by Sámi teachers to more non-Sámi students, and we present a revised teaching plan. However, because there is a significant lack of Sámi teachers, we recommend that non-Sámi teachers use our plan as a model for teaching Sámi traditional measuring. Full article

Gap dynamics are driving many important processes in the development of temperate forest ecosystems. What remains largely unknown is how often the regeneration processes initialized by endogenous mortality of dominant and co-dominant canopy trees take place. We conducted a study in the high mountain forests of the Central Western Carpathians, naturally dominated by the Norway spruce. Based on the repeated forest inventories in two localities, we quantified the structure and amount of deadwood, as well as the associated mortality of standing dead canopy trees. We determined the basic specific gravity of wood and anatomical changes in the initial phase of wood decomposition. The approach for estimating the rate of gap formation and the number of canopy trees per unit area needed for intentional gap formation was formulated based on residence time analysis of three localities. The initial phase of gap formation (standing dead tree in the first decay class) had a narrow range of residence values, with a 90–95% probability that gap age was less than 10 or 13 years. Correspondingly, a relatively constant absolute number of 12 and 13 canopy spruce trees per hectare died standing in 10 years, with a mean diameter reaching 50–58 cm. Maximum diameters trees (70–80 cm) were represented by 1–4 stems per hectare. The values of the wood-specific gravity of standing trees were around 0.370–0.380 g.cm⁻³, and varied from 0.302 to 0.523 g.cm⁻³. Microscopically, our results point out that gap formation is a continuous long-lasting process, starting while canopy trees are living. We observed early signs of wood degradation and bacteria, possibly associated with bark beetles, that induce a strong effect when attacking living trees with vigorous defenses. New information about the initial phase of gap formation has provided a basis for the objective proposal of intervals and intensities of interventions, designed to promote a diversified structure and the long-term ecological stability of the mountain spruce stands in changing climate conditions. Full article

Recently, it has been hypothesized that alpha-synuclein protein strain morphology may be associated with clinical subtypes of alpha-synucleinopathies, like Parkinson’s disease and multiple system atrophy. However, direct evidence is lacking due to the caveat of conformation-specific characterization of protein strain morphology. Here we present a new cell model based in vitro method to explore various alpha-synuclein (αsyn) aggregate morphotypes. We performed a spectroscopic investigation of the HEK293 cell model, transfected with human wildtype-αsyn and A53T-αsyn variants, using the amyloid fibril-specific heptameric luminescent oligomeric thiophene h-FTAA. The spectral profile of h-FTAA binding to aggregates displayed a blue-shifted spectrum with a fluorescence decay time longer than in PBS, suggesting a hydrophobic binding site. In vitro spectroscopic binding characterization of h-FTAA with αsyn pre-formed fibrils suggested a binding dissociation constant K_d < 100 nM. The cells expressing the A53T-αsyn and human wildtype-αsyn were exposed to recombinant pre-formed fibrils of human αsyn. The ensuing intracellular aggregates were stained with h-FTAA followed by an evaluation of the spectral features and fluorescence lifetime of intracellular αsyn/h-FTAA, in order to characterize aggregate morphotypes. This study exemplifies the use of cell culture together with conformation-specific ligands to characterize strain morphology by investigating the spectral profiles and fluorescence lifetime of h-FTAA, based upon its binding to a certain αsyn aggregate. This study paves the way for toxicity studies of different αsyn strains in vitro and in vivo. Accurate differentiation of specific alpha-synucleinopathies is still limited to advanced disease stages. However, early subtype-specific diagnosis is of the utmost importance for prognosis and treatment response. The potential association of αsyn aggregates morphotypes detected in biopsies or fluids to disease phenotypes would allow for subtype-specific diagnosis in subclinical disease stage and potentially reveal new subtype-specific treatment targets. Notably, the method may be applied to the entire spectrum of neurodegenerative diseases by using a combination of conformation-specific ligands in a physicochemical environment together with other types of polymorphic amyloid variants and assess the conformation-specific features of various protein pathologies. Full article

After the onset of the armed conflict between Russia and Ukraine, Poland was forced to change its markets for sourcing raw materials, specifically oil and gas. Simultaneously, as a member of the EU and due to its geographical location in Europe, Poland must meet emission standards and ensure energy security. The aim of this publication is to analyze and evaluate the management of the fuel supply chain (FSC) in Poland in the context of energy security. The main research question formulated is to what extent the management of the FSC can ensure Poland’s energy security. The publication employs two models: MAED (Model for Analysis of Energy Demand) and CDM (canonical distribution model). The research is based on data from the Statistical Office and data provided by the fuel industry. Between 2021 and 2023, Poland diversified its supply sources, mainly from Saudi Arabia (45.2%) and Norway (35.2%), which together account for 80.4% of imports. The current fuel storage capacity (15.05 million m³) is capable of securing production logistics in the event of SC disruptions and market uncertainties. The shift in fuel supply logistics during the discussed period, along with the increase in the fuel safety stock coefficient to quantities exceeding current demand in case of further disruptions caused by external factors, affects the security of the Polish state as well as neighboring countries in Central Europe. Distribution logistics are managed domestically through networks of fuel stations operated by Polish and foreign corporations, including a group of independently owned private fuel stations (47.5%). The fuel industry in Poland has risen to the challenge, maintaining the stability of fuel supplies and their prices. Full article