Search Results (477)

Background: Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide. Although lipid-derived atherogenic indices are widely used for cardiovascular risk assessment, their relationship with sociodemographic factors, lifestyle behaviors, and health-related quality of life (HRQoL) in occupational populations remains insufficiently explored. This study aimed to evaluate the association between atherogenic risk, measured by total cholesterol/high-density lipoprotein cholesterol (TC/HDL-c), low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL-c/HDL-c), triglyceride/high-density lipoprotein cholesterol (TG/HDL-c), and atherogenic dyslipidemia (AD) and sociodemographic, lifestyle, and HRQoL variables in a large cohort of Spanish workers. Methods: We conducted a cross-sectional analysis of 100,014 Spanish workers aged 18–69 years, of whom 39.9% were women, with a mean age of 38.2 years (SD 10.2 or IQR) and 38.9 years (SD 10.3 or IQR) for men, during the health examinations carried out between 2021 and 2024. Sociodemographic variables included sex, age group, and occupational social class. Lifestyle factors comprised smoking status, adherence to the Mediterranean diet (MEDAS score), and physical activity (IPAQ categories). HRQoL was assessed using the 12-item Short Form Survey (SF-12), stratified into good vs. poor categories. Logistic regression models were applied to estimate odds ratios (OR) and 95% confidence intervals (CI) for moderate-to-high atherogenic risk across indices, adjusting for potential confounders. Results: Men exhibited a lower likelihood of moderate-to-high TC/HDL-c and LDL-c/HDL-c but a markedly higher probability of elevated TG/HDL-c and AD compared to women (OR range: 0.42–3.67, p < 0.001). A clear age-related gradient was observed across all indices, with participants aged 60–69 showing the highest risk (OR range: 2.28–7.84, p < 0.001). Lower social class, smoking, physical inactivity, poor diet, and poor SF-12 scores were significantly associated with increased atherogenic risk, with physical inactivity (OR up to 8.61) and poor diet (OR up to 4.98) emerging as the strongest predictors. Conclusions: Atherogenic risk in this large working cohort is strongly influenced by both traditional cardiovascular risk factors and HRQoL. Integrating lifestyle modification and quality-of-life improvement strategies into workplace health programs could substantially reduce the atherogenic burden. Longitudinal research is needed to confirm these associations and guide targeted interventions. Full article

Cement production significantly contributes to global CO₂ emissions. Limestone Calcined Clay Cement (LC³)—a mixture of limestone, calcined clay, cement clinker, and gypsum—offers a promising alternative by significantly reducing clinker contents without compromising mechanical performance. This study assesses the environmental and social hotspots of various LC³ mortars produced in Germany, a context not yet explored in previous research. While prior studies have mostly focused on LC³ in concrete applications and in low- to middle-income countries, this is the first to evaluate LC³-based mortar in a high-income, highly industrialized context using both Life Cycle Assessment (LCA) and Social Risk Assessment (SRA) to determine the main environmental and social drivers of this material. The LCA revealed that LC³ mixtures achieve substantial reductions in key impact categories compared to conventional Ordinary Portland Cement (OPC) mixes, including Climate Change (up to 42.6% reduction) and Particulate Matter (up to 15.8% reduction). The SRA highlights significant social risks related to corruption, fair competition, and workers’ rights, including fair wages, discrimination, and safe working conditions. This study underscores LC³ as a promising sustainable solution in cement applications while emphasizing the importance of region-specific assessments to address unique environmental and social considerations. Full article

Workstations in deep underground mines are among the most dangerous in the world. Workers are exposed to various hazards such as water hazards, climate hazards, and gas hazards. In this article, the authors proposed the most suitable method for measuring nitrogen oxides, such as nitric oxide(NO) and nitrogen dioxide (NO₂), under actual underground mine conditions. The selection of the method was based on a literature review, in which the authors presented a brief characterization of available measurement methods and proposed their classification into four categories: chemical methods, electrochemical methods, chemiluminescence methods, and analytical methods. A SWOT analysis was used to select the appropriate method for NOx determination. The authors focused on identifying the most universal method that can handle measurements in the harsh conditions of underground mines, with an emphasis on ease of use in the field. Due to the mine atmosphere being rich in harmful substances, the selectivity of the method was also taken into account. The method chosen by the authors is intended for measuring both low concentrations of NOx (in the atmosphere) and high concentrations (diesel exhaust emissions). Because of the versatility of the method and its potential application in both small and large laboratories, the cost criterion was also considered. Full article

Background: The relationship between occupational sun exposure and melanoma risk is complex and multifaceted, with existing evidence yielding contradictory findings. Unlike Non-Melanoma Skin Cancer (NMSC), for which occupational sun exposure is a well-established risk factor, the link with cutaneous melanoma remains contentious. Objectives: This study aimed to evaluate whether, in a cohort of patients with cutaneous melanoma, an association existed between occupational sun exposure and melanoma, specifically with histotype, site of occurrence, and Breslow index. Methods: This is a retrospective cohort analysis conducted to evaluate whether occupational sun exposure constitutes a risk factor for the development of cutaneous melanoma in patients diagnosed between January 2005 and October 2023 at the Dermatology Unit, Azienda USL Toscana Centro, Florence. Occupational ultraviolet (UV) exposure was examined by classifying each participant’s job into categories based on solar UV exposure levels—outdoor (e.g., agriculture and construction roles), mixed indoor/outdoor (e.g., trades and public safety professions), and indoor settings (e.g., office-based work). Results: A final total of 1417 patients were analyzed. Occupational categorization revealed that 1171 patients (82.64%) were classified as non-occupationally exposed (indoor), while 246 (17.36%) were occupationally exposed to solar UV radiation (including 14.82% mixed indoor/outdoor and 2.54% outdoor workers). A significant association was observed between occupational sun exposure and lentigo maligna, which was more prevalent among exposed workers and even more so in the outdoor subgroup. Anatomical site distribution exhibited a significant association with occupational sun exposure. Indeed occupationally exposed individuals showed a higher prevalence of melanomas in the head and neck region, a distribution pattern particularly evident among outdoor workers, suggesting that these sites may be more susceptible to chronic sun exposure in outdoor and mixed occupations. Moreover, a significant association was found between occupational exposure and Breslow thickness, with exposed workers presenting with thicker melanomas at diagnosis, suggesting more advanced disease. Conclusions: The finding of this study may reflect variations in occupational sun exposure patterns and warrants further investigation into protective measures and early-detection strategies tailored to occupational groups. Full article

The hyperbaric environment, to which many categories of workers are exposed, can provoke injuries that can lead to various types of disorders. A major part of the studies aiming to explore the causes/effects leading to these injuries are conducted in vivo. In the present manuscript, we describe the effects on osteoblast cell cultures stressed in a hyperbaric purpose-built chamber, using an in vitro model to analyze the affected pathways. A hyperbaric chamber for cell cultures was constructed by adapting a pressurized test chamber originally designed for technical use. The MG-63 cell line and human primary osteoblasts were placed into this chamber at different atm and exposure times, at 37 °C. After treatment, the chamber was depressurized by performing controlled decompression stops. Then, the pro-inflammatory cytokines and bone tissue biomarker expression were analyzed. The stress conditions induced the overexpression of pro-inflammatory cytokines, such as IL-6, IL-1β, and TNF-α, along with reactive oxygen species release. Moreover, the alteration of bone tissue marker production was observed. In particular, the increase in Receptor Activator of NF-κB Ligand (RANKL) and the decrease in Osteoprotegerin (OPG) were detected. Further modulation was observed regarding other biomarkers, Alkaline phosphatase, Osteocalcin, Bone Morphogenetic Protein-2, and mainly Collagen type I, all of which were downregulated by treatment. Taken together, these findings account for certain illnesses, such as dysbaric osteonecrosis, diagnosed in workers exposed to a hyperbaric environment. Inflammation induced by this kind of stress affects several factors involved in bone tissue homeostasis, leading to bone injuries, which are among the typical disorders observed in divers. Full article

Background: Type 2 diabetes (T2D) is a major global health concern influenced by sociodemographic and lifestyle factors. This study compared T2D risk scores between commerce and industry sectors and assessed the associations of age, sex, education, physical activity, diet, and smoking with elevated risk. Methods: This cross-sectional study included 56,856 men and 12,872 women employed in the commerce (n = 27,448) and industry (n = 42,280) sectors across Spain. Anthropometric, clinical, and biochemical data were collected. Four validated T2D risk scores (QDscore, Finrisk, Canrisk, and TRAQ-D) were calculated. Multinomial logistic regression models estimated adjusted odds ratios (ORs) for high-risk categories by sociodemographic and lifestyle characteristics. Results: Women in the industrial sector had significantly higher age, BMI, waist circumference, and lipid levels than those in commerce; differences among men were less marked. Across all participants, higher T2D risk scores were independently associated with physical inactivity (OR up to 12.49), poor Mediterranean diet adherence (OR up to 6.62), industrial employment (OR up to 1.98), and older age. Male sex was strongly associated with high Canrisk scores (OR = 6.31; 95% CI: 5.12–7.51). Conclusions: Employment in the industrial sector, combined with sedentary behavior and poor dietary habits, is independently associated with higher predicted T2D risk. Workplace prevention strategies should prioritize multicomponent interventions targeting modifiable risk factors, especially in high-risk subgroups such as older, less-educated, and inactive workers. Full article

Certain industries will bear a disproportionate share of the burden of climate change. Climate change risk perceptions can impact workers’ mental health and well-being; increased climate change risk perceptions are also associated with more favourable adaptive attitudes. It is, therefore, important to understand whether climate risk perceptions differ across workers between industries. We conducted an online survey of British Columbians (16+) in 2021 using social media advertisements. Participants rated how likely they believed their industry (Natural Resources, Science, Art and Recreation, Education/Law/Government, Health, Management/Business, Manufacturing, Sales, Trades) would be affected by climate change (on a scale from “Very Unlikely” to “Very Likely”). Ordinal logistic regression examined the association between occupational category and perceived industry vulnerability, adjusting for socio-demographic factors. Among 877 participants, 66.1% of Natural Resources workers perceived it was very/somewhat likely that climate change would impact their industry; only those in Science (78.3%) and Art and Recreation (71.4%) occupations had higher percentages. In the adjusted model, compared to Natural Resources workers, respondents in other occupations, including those in Art and Recreation, Education/Law/Government, Management/Business, Manufacturing, Sales, and Trades, perceived significantly lower risk of climate change-related industry impacts. Industry-specific interventions are needed to increase awareness of and readiness for climate adaptation. Policymakers and industry leaders should prioritize sectoral differences when designing interventions to support climate resilience in the workforce. Full article

The pattern of labour underutilisation is complex and multifaceted, but research has been focused on unemployment. To explore socio-economic demographics of other forms of labour underutilisation, this study investigates the concept of ‘hidden workers’ using the latest data from the Household, Income and Labour Dynamics in Australia (HILDA) study. Hidden workers are composed of three categories, namely those who are unemployed but actively seeking employment; working part-time but willing and able to work full-time; and not working but are willing and able to work under the right conditions. Analysis of HILDA data from 2022 reveals (i) a significant discrepancy in the incidence of unemployed and hidden workers across various socio-economic factors, and (ii) a pronounced age and gender differences among hidden workers, which is not easily discernible from standard unemployment descriptive statistics. Effective labour market policy depends on accurately identifying the different types of hidden workers and their social determinants. This study offers valuable insights to support more inclusive policies for hidden workers, who are often overlooked. Full article

Background/Objectives: The aging of workers with intellectual and developmental disabilities is an emerging reality attributed to the rise in life expectancy and improved labor market access. In this study, “workers” is used as an inclusive, neutral term covering all individuals engaged in paid labor—whether employees, self-employed, freelancers, or those performing manual or non-manual tasks. It encompasses every form of work. It is crucial to comprehend the reality of aging workers from the perspectives of the primary individuals involved: the workers, their families, and supporting professionals. Methods: A qualitative study was developed, involving 12 focus groups and 107 participants, using NVivo 12 Pro for analysis; we used a phenomenological methodology and grounded theory. Results: A set of concrete needs was highlighted: among them, 33 were related to declining work ability due to aging and disability (WADAD), and 30 to transition to retirement. These needs were grouped into categories: workplace accommodations, coordination and collaboration, personal and family support, counseling and training, and other types of needs. Conclusions: This study establishes an empirical basis tailored to the needs of this group, enabling the development of prevention and intervention protocols that address WADAD and the transition to retirement. Full article

Technology-based strategies for the prevention and management of suicidal behavior are widely referenced for identifying vulnerable groups and for supporting clinical reasoning, decision-making, and appropriate referrals. In this study, we estimated the interface and content validity evidence of an interactive mobile application developed for managing suicidal behavior. This methodological study employed psychometric parameters to evaluate the content and interface of the mobile application, following five action phases: analysis, design, development, implementation, and evaluation. A total of 27 healthcare professionals participated, selected by convenience sampling, all working within the Psychosocial Care Network across different regions of Brazil. Data were collected using an electronic form, the Delphi technique for evaluation rounds, and a Likert scale to achieve consensus. The validity analysis was based on a Content Validity Index (CVI) equal to or greater than 0.80. The results showed that GerenciaVida, a technology developed for healthcare workers—regardless of their level of care or professional category—can be used to screen for suicide risk in the general population and indicate preventive alternatives. The app demonstrated satisfactory indicators of content validity (0.974) and interface validity (0.963), reflecting clarity (0.925), objectivity (1.00), adequacy (0.925), coherence (0.962), accuracy (0.962), and clinical relevance (1.00). The development path of this mobile application provided scientific, technological, and operational support, establishing it as an innovative care tool. It consolidates valid evidence that supports the identification, risk classification, and prevention of suicidal behavior in various healthcare contexts. Full article

Road infrastructure is the foundation of the predominant modes of transport, and its effective management is crucial to meet mobility needs. Although necessary for reconstruction, maintenance, and expansion projects, roadworks produce negative impacts, resulting in further risk for workers and drivers and failing to ensure sustainable development. The objective of this paper is twofold: Firstly, investigate the contributing factors to the occurrence of crashes in roadworks. Secondly, develop a model to estimate crash numbers in these areas. The results, which could support municipalities at the planning stage and implement policies for safe and sustainable development, are achieved by examining 121 sites, where 549 crashes occurred, and 25 contributing factors. The variables are divided into three categories: technical characteristics of the site, infrastructural, and environmental. Besides the conventional variables, a risk-increasing factor is calibrated. It assesses the impact of roadworks according to the manoeuvres imposed and the number of lanes. Consistent with previous findings, several variables related to the work zone layout, traffic conditions, infrastructure, and surrounding environment are correlated with the crash number. After performing a further statistical analysis, a multiple linear regression model, statistically significant (0.000) and suitable for accurately estimating the possible number of crashes (R²_adj = 0.41), is determined. Full article

The forestry sector is increasingly dealing with a significant lack of labor and faces the difficult task of securing a professional, stable and sustainable manpower. In this study, different strategic directions for strengthening forestry workforce sustainability are presented and evaluated. The considered strategic directions were developed with respect to forestry employees’ views on necessary measures for making the forestry occupation more appealing. Those measures were observed in three categories: (I) stronger recruiting, (II) stronger retention and (III) higher work commitment. The findings of the survey and other performed analyses resulted in the creation of four different strategic directions: (1) the direct financial strategy, implying increased direct monetary compensation as the main instrument and putting focus on labor productivity; (2) the indirect financial strategy, stressing worker wellbeing through indirect material benefits and aiming at performance quality; (3) the educational strategy, focusing on worker training and education and (4) the technical–technological strategy, aiming at the increased utilization of modern machinery and advanced technologies in forest operations. The results of the study include a comparison of the defined strategies by SWOT analysis and the construction of An analytic Hierarchy Process (AHP) model as the multi-criteria tool for strategy evaluation. Considering the possibility and conditions of its implementation in the national forestry sector, the technical–technological strategy has been evaluated as best option to pursue. The objective of the study is to contribute to enhancing the sustainability of forestry workforce by defining critical issues and pointing to specific cornerstones that can assist in formulating effective future policies and strategies in the forestry sector. Full article

With the increasing demands of long-term overseas assignments, workers in isolated environments, such as maritime crews, often experience heightened psychological stress and a lack of accessible emotional support. This study investigates the effectiveness of online song intervention program based on contextual support model in reducing work-related distress and enhancing psychological resilience among the ship crews dispatched for an extensive period for work. Eighteen overseas workers participated in a four-week intervention that included both individual and group sessions, where they engaged with songs to cultivate personal and interpersonal resources. A deductive content analysis following the intervention revealed 3 main categories, 6 generic categories, and 14 subcategories. The three main categories identified were relationships, autonomy, and mood regulation. The relationships category encompassed support systems and bonding, focusing on empathy, consolation, positive perspective, vicarious empowerment, trust, and changes of perspective. Autonomy involved fostering a sense of control and fulfillment through determination, anticipation, motivation, and achievement. Mood regulation was divided into grounding and emotional resolution, which included containment, sedation, externalization, and ventilation. The findings highlight that song lyrics offer valuable insights for developing resources aimed at mood regulation, social support, and self-efficacy, helping to alleviate work-related stress during dispatch periods. Songs also foster a sense of control, competence, and relational connectedness, with mood regulation emerging as a key feature of their emotional impact. These results suggest that incorporating songs with lyrics focused on personal and interpersonal resources could be an effective strategy to support remotely dispatched workers. Furthermore, this approach appears to be a viable and scalable solution for online programs. Full article

(1) Background: Work-related musculoskeletal disorders (WMSDs) are a major occupational health concern in the construction industry owing to the physically demanding tasks and poor ergonomic conditions present. Limited data exist on the prevalence of WMSDs and their ergonomic determinants among construction workers in India. This study investigated the prevalence of work-related musculoskeletal disorders (WMSDs) and the associated ergonomic risk factors among construction workers in India. (2) Methods: This cross-sectional study was conducted among 250 construction workers in India. Data on musculoskeletal disorders were collected using the Nordic Musculoskeletal Questionnaire (NMQ), and ergonomic risk was assessed using the Rapid Entire Body Assessment (REBA) tool. Logistic regression was used to identify factors associated with WMSDs, and Spearman’s correlation was used to assess the relationship between the REBA scores and the number of affected body regions. (3) Results: The prevalence of WMSDs was 60.4%. The most affected regions were the lower back (48%), knees (45%), shoulders (40%), and the neck (30%). The REBA scores indicated that 60% of the workers were at high or very high ergonomic risk and 30% at medium risk. Workers in the high/very high-risk category had significantly higher odds of developing WMSDs (OR = 4.5, 95% CI: 1.8–11.2, p = 0.001). Age above 40 years was also significantly associated with WMSDs (OR = 3.5, 95% CI: 1.2–10.2, p = 0.02). (4) Conclusions: This study demonstrated a high prevalence of WMSDs among Indian construction workers and established a clear association with poor ergonomic conditions. Targeted ergonomic interventions, including posture improvement, tool redesign, and safety training, are essential for reducing the risk of WMSDs in this population. Full article

Background: Thimerosal has been widely used as a preservative to prevent microbial growth in medications and vaccines. However, in 1999 its removal from vaccine formulations was called for due to concerns about its potential side effects on humans, with subsequent reduced sensitizations at patch tests. The present multi-center study investigated the epidemiological, occupational and temporal pattern of sensitization to Thimerosal in North-Eastern Italy during 1997–2023 and associated factors. Methods: Due to variability in patch testing and positive reactions by the centers, this study was broken down by three periods: 1997–2004 (including all centers but Trieste); 1997–2015 (considering only Padua and Pordenone); and 2010–2023 (considering only Trieste and Pordenone). Multiple logistic regression was used to investigate prevalence of sensitization to Thimerosal and associated factors. Results were expressed as adjusted odds ratio (aOR) with 95% confidence intervals (95%CI). Results: Prevalence of positive patch test reactions to Thimerosal decreased from (8.13%) in 1997 to 0.95% in 2023 across all centers combined. Prevalence of positivity to Thimerosal was 9.49% during 1997–2004 (in all centers yet excluding Trieste), 8.41% during 1997–2015 (considering only Padua and Pordenone) and 4.01% during 2010–2023 (considering only Trieste and Pordenone). A significantly decreasing trend of Thimerosal sensitization was observed during 1997–2015 (aOR = 0.94; 95%CI: 0.92; 0.95). Regardless of the study period, sensitization to Thimerosal was consistently and significantly higher among health care workers (HCWs) and in patients born during 1981–1990. Conclusions: The significantly decreasing prevalence of sensitization to Thimerosal over time likely reflected removal policies from vaccines and medications after 1999. Likewise, the higher prevalence of patch test reactions in patients born during 1981–1990 may mirror the widespread presence of this hapten in vaccines and medications in the 1980ies. Moreover, the increased prevalence of patch test reactions positive to Thimerosal in HCWs probably reflected higher influenza vaccination uptake in this group compared to other occupational categories. Positive patch test reactions to Thimerosal after 2000 were likely clinically irrelevant though. Full article