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46 Results Found

  • Article
  • Open Access
381 Views
23 Pages

2 September 2026

As critical minerals required for the production of new energy batteries, the demand forecasts and trends for Li, Co, Ni, and Mn are of crucial importance for ensuring the energy transition and China’s sustainable development. This study has de...

(This article belongs to the Special Issue Innovative Pathways of Renewable Energy for Sustainable Development)
  • Article
  • Open Access
49 Citations
6,481 Views
18 Pages

15 May 2020

The article presents an assessment of the potential for using low temperature geothermal water from the C-PIG-1 well (Małopolskie Voivodship, southern Poland) for electricity generation, as the first stage in a geothermal cascade system. The C-PIG-1...

(This article belongs to the Special Issue Assessment, Management and Treatment of Waters and Geothermal Systems)
  • Article
  • Open Access
29 Citations
7,944 Views
18 Pages

11 October 2019

In this paper, a heat driven cooling system that essentially integrated an organic Rankine cycle power plant with a vapour compression cycle refrigerator was investigated, aiming to provide an alternative to absorption refrigeration systems. The orga...

(This article belongs to the Section Energy Science and Technology)
  • Article
  • Open Access
617 Views
19 Pages

Hearing Impairment in Kazakhstan, 2020–2025: Dispensary Registration, Disability Certification, and Cochlear Implantation Response, with Reference to Global Burden of Disease 2021 Modelled Estimates

  • Zhadra Bukenova,
  • Galiya Orazova,
  • Aigerim Baimagambetova,
  • Zhadyra Karashutova,
  • Aisulu Talgatova,
  • Zulfiya Zholdybayeva,
  • Sauran Yerdessov and
  • Gulnara Kulkayeva

Background: Hearing health in Kazakhstan is documented through parallel administrative systems whose indicators are often conflated. We examined three administrative layers of hearing health during 2020–2025: dispensary registration of ear and...

  • Article
  • Open Access
10 Citations
5,506 Views
16 Pages

A Novel Concept for Three-Phase Cascaded Multilevel Inverter Topologies

  • Md Mubashwar Hasan,
  • A. Abu-Siada,
  • Syed M. Islam and
  • S. M. Muyeen

23 January 2018

One of the key challenges in multilevel inverters (MLIs) design is to reduce the number of components used in the implementation while maximising the number of output voltage levels. This paper proposes a new concept that facilitates a device count r...

(This article belongs to the Section F: Electrical Engineering)
  • Article
  • Open Access
15 Citations
2,398 Views
15 Pages

22 March 2024

Poultry and forestry waste residues, despite their environmental concerns, offer nutrient-rich content and wider availability. Utilising them in cascading approaches can create high-value products and establish new value chains in bioeconomy. This st...

(This article belongs to the Special Issue New Trends in Biofuels and Bioenergy for Sustainable Development II)
  • Review
  • Open Access
5 Citations
6,071 Views
15 Pages

19 August 2018

A model of signal transduction from the perspective of informational thermodynamics has been reported in recent studies, and several important achievements have been obtained. The first achievement is that signal transduction can be modelled as a bin...

(This article belongs to the Section Information Theory, Probability and Statistics)
  • Article
  • Open Access
1 Citations
2,211 Views
24 Pages

26 September 2024

In the context of locomotive traction systems, the power electronic traction transformer (PETT) represents a pivotal component, fulfilling essential functions pertaining to electrical isolation and power control. The majority of existing PETT prototy...

  • Article
  • Open Access
1,854 Views
22 Pages

Development of a Software and Hardware Complex for Monitoring Processes in Production Systems

  • Vadim Pechenin,
  • Rustam Paringer,
  • Nikolay Ruzanov and
  • Aleksandr Khaimovich

28 February 2025

The article presents a detailed exposition of a hardware–software complex that has been developed for the purpose of enhancing the productivity of accounting for the state of the production process. This complex facilitates the automation of th...

(This article belongs to the Special Issue Computer Vision and Sensors-Based Application for Intelligent Systems)
  • Article
  • Open Access
46 Citations
18,351 Views
22 Pages

6 August 2023

Despite advancements, Smart Cities encounter hazards. Smart Cities’ higher reliance on interconnected systems and networks makes them susceptible to risks beyond conventional ones, leading to cascading effects. Hence, the effective use of techn...

(This article belongs to the Special Issue Integrating Climate Change Adaptation and Disaster Risk Reduction in Cities: Approaches, Methods and Tools to Overcome the Implementation Gap in Urban Resilience)
  • Article
  • Open Access
2 Citations
2,841 Views
18 Pages

29 July 2021

Across various scenarios, individuals cooperate with others to contribute towards a shared goal and ensure self-preservation. In game theory, the act of cooperation is considered as an individual producing some form of benefit to be utilised by other...

(This article belongs to the Section E: Applied Mathematics)
  • Article
  • Open Access
4 Citations
2,239 Views
15 Pages

10 July 2023

Goat’s milk is an excellent source of nutrients, with greater benefits compared to cow’s milk. Limited information is available on autochthon goat breeds, which are important for biodiversity preservation. In this study, the aim of using...

(This article belongs to the Section Small Ruminants)
  • Review
  • Open Access
75 Citations
11,490 Views
29 Pages

The importance of Ca2+ signalling in key events of cancer cell function and tumour progression, such as proliferation, migration, invasion and survival, has recently begun to be appreciated. Many cellular Ca2+-stimulated signalling cascades utilise t...

(This article belongs to the Special Issue Protein Kinases and Cancer)
  • Article
  • Open Access
5 Citations
3,887 Views
15 Pages

The Facilitators and Barriers of Adopting Amylase-Rich Flour to Enhance Complementary Foods in the Kersa District Community of Eastern Ethiopia

  • Asnake Ararsa Irenso,
  • Shiferaw Letta,
  • Addisu S. Chemeda,
  • Abiyot Asfaw,
  • Gudina Egata,
  • Nega Assefa,
  • Karen J. Campbell and
  • Rachel Laws

4 March 2021

Achieving the optimal transition to a family diet over the first two years of life has remained a challenge in Ethiopia. The use of amylase-rich flour (ARF) can improve complementary foods. However, utilisation requires an effective delivery strategy...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
39 Citations
17,290 Views
20 Pages

Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus)

  • Jordan Debono,
  • James Dobson,
  • Nicholas R. Casewell,
  • Anthony Romilio,
  • Bin Li,
  • Nyoman Kurniawan,
  • Karine Mardon,
  • Vera Weisbecker,
  • Amanda Nouwens and
  • Bryan G. Fry
  • + 1 author

19 May 2017

Venoms can deleteriously affect any physiological system reachable by the bloodstream, including directly interfering with the coagulation cascade. Such coagulopathic toxins may be anticoagulants or procoagulants. Snake venoms are unique in their use...

(This article belongs to the Section Animal Venoms)
  • Review
  • Open Access
5 Citations
3,378 Views
16 Pages

30 January 2024

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the elderly in the developed world. Whilst AMD is a multifactorial disease, the involvement of the complement system in its pathology is well documented, wi...

(This article belongs to the Section Molecular Immunology)
  • Article
  • Open Access
52 Citations
4,073 Views
18 Pages

Design and Implementation a Single-Switch Step-Up DC-DC Converter Based on Cascaded Boost and Luo Converters

  • Hossein Gholizadeh,
  • Reza Sharifi Shahrivar,
  • Mir Reza Hashemi,
  • Ebrahim Afjei and
  • Saman A. Gorji

16 June 2021

We designed and implemented a single-switch step-up DC-DC converter based on cascaded boost and Luo converters. The proposed converter demonstrated a quadratic voltage gain and a high efficiency, which makes it suitable for renewable energy applicati...

  • Article
  • Open Access
5 Citations
6,663 Views
25 Pages

Fuel cell hybrid vehicles represent an alternative to battery electric vehicles and will gain importance in the future as they do not need large battery capacities and thus require less critical raw materials. Depending on the electric architecture,...

(This article belongs to the Section Inventions and Innovation in Advanced Manufacturing)
  • Article
  • Open Access
5 Citations
3,962 Views
9 Pages

24 January 2025

The integration of automated tools in engineering education has the potential to improve student assessments, ensuring consistency and reducing instructor workload. This study introduces a Python-based automation tool designed to evaluate student Com...

(This article belongs to the Special Issue Advances in Sports Training and Biomechanics)
  • Article
  • Open Access
6 Citations
3,622 Views
13 Pages

Proteomics-Based Serum Alterations of the Human Protein Expression after Out-of-Hospital Cardiac Arrest: Pilot Study for Prognostication of Survivors vs. Non-Survivors at Day 1 after Return of Spontaneous Circulation (ROSC)

  • Jochen Hinkelbein,
  • Lydia Kolaparambil Varghese Johnson,
  • Nikolai Kiselev,
  • Jan Schmitz,
  • Martin Hellmich,
  • Hendrik Drinhaus,
  • Theresa Lichtenstein,
  • Christian Storm and
  • Christoph Adler

14 February 2022

Background: Targeted temperature management (TTM) is considered standard therapy for patients after out-of-hospital cardiac arrest (OHCA), cardiopulmonary resuscitation (CPR), and return of spontaneous circulation (ROSC). To date, valid protein marke...

(This article belongs to the Special Issue Cardiopulmonary Resuscitation: Clinical Updates and Perspectives)
  • Article
  • Open Access
7 Citations
2,660 Views
16 Pages

UAV Image Small Object Detection Based on RSAD Algorithm

  • Jian Song,
  • Zhihong Yu,
  • Guimei Qi,
  • Qiang Su,
  • Jingjing Xie and
  • Wenhang Liu

20 October 2023

There are many small objects in UAV images, and the object scale varies greatly. When the SSD algorithm detects them, the backbone network’s feature extraction capabilities are poor; it does not fully utilize the semantic information in the dee...

  • Article
  • Open Access
7 Citations
3,898 Views
32 Pages

Highly Adaptive Reconfigurable Receiver Front-End for 5G and Satellite Applications

  • Mfonobong Uko,
  • Sunday Ekpo,
  • Sunday Enahoro,
  • Fanuel Elias,
  • Rahul Unnikrishnan and
  • Yasir Al-Yasir

The deployment of fifth-generation (5G) and beyond-5G wireless communication systems necessitates advanced transceiver architectures to support high data rates, spectrum efficiency, and energy-efficient designs. This paper presents a highly adaptive...

  • Article
  • Open Access
1 Citations
1,367 Views
18 Pages

20 January 2026

This study evaluates the environmental outcomes of integrating anaerobic digestion (AD) with pyrolysis (Py) and hydrothermal carbonization (HTC) to treat cattle slurry and grass silage in an Irish agricultural context. A consequential life cycle asse...

(This article belongs to the Special Issue Sustainable Waste Utilisation and Biomass Energy Production)
  • Review
  • Open Access
19 Citations
3,169 Views
30 Pages

15 February 2023

In recent decades the power system has become a complex network, to design a load frequency control (LFC) requires solving a complex equation. Optimisation techniques are essentially required to optimise the parameters of different controllers used f...

  • Article
  • Open Access
12 Citations
7,937 Views
19 Pages

12 January 2018

Spatial impulse response analysis techniques are commonly used in the field of acoustics, as they help to characterise the interaction of sound with an enclosed environment. This paper presents a novel approach for spatial analyses of binaural impuls...

(This article belongs to the Special Issue Sound and Music Computing)
  • Article
  • Open Access
23 Citations
5,895 Views
34 Pages

A Process Integration Method for Total Site Cooling, Heating and Power Optimisation with Trigeneration Systems

  • Khairulnadzmi Jamaluddin,
  • Sharifah Rafidah Wan Alwi,
  • Zainuddin Abdul Manan,
  • Khaidzir Hamzah and
  • Jiří Jaromír Klemeš

16 March 2019

Research and development on integrated energy systems such as cogeneration and trigeneration to improve the efficiency of thermal energy as well as fuel utilisation have been a key focus of attention by researchers. Total Site Utility Integration is...

(This article belongs to the Special Issue Selected Papers from PRES 2018: The 21st Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction)
  • Article
  • Open Access
12 Citations
5,082 Views
24 Pages

Regulation of Proline Accumulation and Protein Secretion in Sorghum under Combined Osmotic and Heat Stress

  • Samkelisiwe P. Ngwenya,
  • Sellwane J. Moloi,
  • Nemera G. Shargie,
  • Adrian P. Brown,
  • Stephen Chivasa and
  • Rudo Ngara

6 July 2024

Plants reprogramme their proteome to alter cellular metabolism for effective stress adaptation. Intracellular proteomic responses have been extensively studied, and the extracellular matrix stands as a key hub where peptide signals are generated/proc...

(This article belongs to the Section Plant Response to Abiotic Stress and Climate Change)
  • Review
  • Open Access
2 Citations
302 Views
6 Pages

Veno-arterial extracorporeal membrane oxygenation (ECMO) is utilised as a short-term mechanical circulatory assist device for treatment of refractory acute cardiogenic shock. After a period of support, called “bridge to decision”, the options for ens...

  • Review
  • Open Access
2 Citations
2,845 Views
29 Pages

The Bioenergetic Architecture of Metabolic Regulation: From Gut–Brain Signalling to Next-Generation Peptide Pharmacology

  • Miriana Rega,
  • Francesco Maria Petraglia,
  • Luisa D’Ursi,
  • Michela Buonocore,
  • Diego Criscuolo and
  • Angelo Santoro

Energy homeostasis arises from a complex interplay between gut-derived hormones, the central nervous system, and pancreatic function. Beyond the classical incretin axis, a broad spectrum of gut peptides acts in concert to coordinate appetite regulati...

  • Article
  • Open Access
15 Citations
4,971 Views
29 Pages

26 August 2020

A 10 kW PEMFC (polymer exchange membrane fuel cell) stack consisting of two 5 kW modules, (A) and (B), connected in series with a multi-function controller unit was constructed and tested. The electrical performance of the V-shaped PEMFC stack was in...

(This article belongs to the Section A5: Hydrogen Energy)
  • Article
  • Open Access
12 Citations
3,836 Views
18 Pages

14 May 2022

In the past two decades, Unmanned Aerial Vehicles (UAVs) have gained attention in applications such as industrial inspection, search and rescue, mapping, and environment monitoring. However, the autonomous navigation capability of UAVs is aggravated...

  • Article
  • Open Access
2 Citations
2,630 Views
16 Pages

The impacts of COVID-19 among men who have sex with men (MSM), who face limited access to HIV services due to stigma, discrimination, and violence, need to be assessed and quantified in terms of HIV treatment outcomes for future pandemic preparedness...

  • Article
  • Open Access
10 Citations
5,352 Views
21 Pages

YB-1 Knockdown Inhibits the Proliferation of Mesothelioma Cells through Multiple Mechanisms

  • Thomas G. Johnson,
  • Karin Schelch,
  • Kaitao Lai,
  • Kamila A. Marzec,
  • Marina Kennerson,
  • Michael Grusch,
  • Glen Reid and
  • Andrew Burgess

14 August 2020

Y-box binding protein-1 (YB-1) is a multifunctional oncoprotein that has been shown to regulate proliferation, invasion and metastasis in a variety of cancer types. We previously demonstrated that YB-1 is overexpressed in mesothelioma cells and its k...

(This article belongs to the Special Issue Close links between Cold Shock Proteins and Cancer)
  • Article
  • Open Access
25 Citations
4,678 Views
28 Pages

DC Link Voltage Enhancement in DC Microgrid Using PV Based High Gain Converter with Cascaded Fuzzy Logic Controller

  • Senthilnathan Rajendran,
  • Vigneysh Thangavel,
  • Narayanan Krishnan and
  • Natarajan Prabaharan

6 May 2023

Renewable-based sources can be interconnected through power electronic converters and connected with local loads and energy storage devices to form a microgrid. Nowadays, DC microgrids are gaining more popularity due to their higher efficiency and re...

(This article belongs to the Special Issue Coordination and Optimization of Energy Management in Smart Grids)
  • Article
  • Open Access
54 Citations
7,742 Views
17 Pages

Achieving Sustainable Phosphorus Use in Food Systems through Circularisation

  • Paul J. A. Withers,
  • Donnacha G. Doody and
  • Roger Sylvester-Bradley

30 May 2018

The notion of a phosphorus (P) circular economy provides the philosophy, framework, and opportunity to enable food production systems to become more efficient, sustainable, and resilient to a future P scarcity or sudden price shock. Whilst P recovery...

(This article belongs to the Special Issue Phosphorus Circular Economy: Closing Loops through Sustainable Innovation)
  • Article
  • Open Access
16 Citations
6,754 Views
24 Pages

5 March 2019

The aim of the study is to develop a real-time eyeblink detection algorithm that can detect eyeblinks during the closing phase for a virtual reality headset (VR headset) and accordingly classify the eye’s current state (open or closed). The pro...

  • Article
  • Open Access
441 Views
34 Pages

The Impact of Blackouts on Urban Energy Resilience: Case Studies from Spain, Portugal, and Poland

  • Ireneusz Miciuła,
  • Iwona Kowalska,
  • Małgorzata Błażejowska,
  • Anna Czarny,
  • Szczepan Stempiński and
  • Małgorzata Zakrzewska-Grünwald

24 July 2026

Long-term and large-scale power outages (blackouts) pose a significant threat to the functioning of modern cities, exposing the level of their preparedness for crisis situations. A blackout is a systemic phenomenon whose cascading impacts extend far...

(This article belongs to the Special Issue Optimizing Energy Consumption in a Global Information Technology World)
  • Article
  • Open Access
109 Citations
13,875 Views
9 Pages

Impact of the Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma (A-PRP) and Activated Platelet-Rich Plasma (AA-PRP) in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation

  • Pietro Gentile,
  • Claudio Calabrese,
  • Barbara De Angelis,
  • Laura Dionisi,
  • Jacopo Pizzicannella,
  • Ashutosh Kothari,
  • Domenico De Fazio and
  • Simone Garcovich

Autologous therapies using platelet-rich plasma (PRP) need meticulous preparation—currently, no standardised preparation technique exists. Processing Quantitative Standards (PQSs) define manufacturing quantitative variables (such as time, volum...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
40 Citations
8,266 Views
16 Pages

Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts

  • Amisha Sanghani,
  • Konstantinos N. Kafetzis,
  • Yusuke Sato,
  • Salsabil Elboraie,
  • Julia Fajardo-Sanchez,
  • Hideyoshi Harashima,
  • Aristides D. Tagalakis and
  • Cynthia Yu-Wai-Man

The master regulator of the fibrosis cascade is the myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway, making it a key target for anti-fibrotic therapeutics. In the past, inhibitors and small interfering RNAs (siRNAs) ta...

(This article belongs to the Special Issue Novel Nanoparticles for Targeted Delivery of Therapeutic Nucleic Acids)
  • Article
  • Open Access
27 Citations
22,915 Views
17 Pages

11 September 2024

This study investigates the profound and multifaceted impacts of Artificial Intelligence (AI) and geopolitical developments on global dynamics by 2040. Utilising a Delphi process coupled with probabilistic modelling, the research constructs detailed...

  • Article
  • Open Access
590 Views
20 Pages

First Exonic Cryptic Branchpoint Variant in an Inherited Retinal Degeneration Detected in an Irish RPGR Pedigree with X-Linked Retinitis Pigmentosa

  • Ella Kopčić,
  • Laura Whelan,
  • Ciara Shortall,
  • Anna R. Ridgeway,
  • Laura K. Finnegan,
  • Adrian Dockery,
  • Sophia Millington-Ward,
  • Emma Duignan,
  • Paul F. Kenna and
  • Naomi Chadderton
  • + 1 author

21 June 2026

Objectives: This study investigated a variant, RPGR NM_001034853.2 c.1307G>A, p.[Gly436Asp, p?], in a large Irish pedigree with severe X-Linked Retinitis Pigmentosa (XLRP). The effect of the variant on RNA splicing was interrogated using in vitro...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
2 Citations
1,292 Views
30 Pages

GIS-Based Site Selection for Agricultural Water Reservoirs: A Case Study of São Brás de Alportel, Portugal

  • Olga Dziuba,
  • Cláudia Custódio,
  • Carlos Otero Silva,
  • Fernando Miguel Granja-Martins,
  • Rui Lança and
  • Helena Maria Fernandez

17 November 2025

In the São Brás de Alportel municipality, water scarcity poses a significant constraint on agricultural activities. This study utilises Remote Sensing (RS) and Geographical Information Systems (GISs) to identify existing irrigated areas...

(This article belongs to the Section Sustainable Water Management)
  • Article
  • Open Access
18 Citations
7,147 Views
35 Pages

Design of FPGA-Based SHE and SPWM Digital Switching Controllers for 21-Level Cascaded H-Bridge Multilevel Inverter Model

  • Emilia Noorsal,
  • Asyraf Rongi,
  • Intan Rahayu Ibrahim,
  • Rosheila Darus,
  • Daniel Kho and
  • Samsul Setumin

25 January 2022

Multilevel inverters are a type of power electronic circuit that converts direct current (DC) to alternating current (AC) for use in high-voltage and high-power applications. Many recent studies on multilevel inverters have used field-programmable ga...

(This article belongs to the Special Issue Smart Embedded Processors)
  • Review
  • Open Access
1,277 Views
19 Pages

From Pandemic to Practice: How COVID-19 Has Reshaped Haemostasis in Cardiac Surgery: A Narrative Review

  • Lydia Wilkinson,
  • Arian Arjomandi Rad,
  • Joshua Oliver and
  • Antonios Kourliouros

16 November 2025

The utilisation of cardiopulmonary bypass (CPB) during cardiac surgery is often associated with complex haemostatic perturbations, frequently manifesting as a paradoxical risk of both bleeding and thrombosis. This is postulated to be driven by system...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
9 Citations
9,033 Views
25 Pages

20 March 2023

Despite mitigation and adaptation efforts, the residual risks of climate change will continue to impact the most vulnerable communities globally. Highly exposed regions, such as the Pacific Islands, will continue to experience profound negative loss...

(This article belongs to the Collection Adaptation and Mitigation Practices and Frameworks)
  • Article
  • Open Access
4 Citations
3,854 Views
16 Pages

Novel LDLR Variant in Familial Hypercholesterolemia: NGS-Based Identification, In Silico Characterization, and Pharmacogenetic Insights

  • Mohammad Athar,
  • Mawaddah Toonsi,
  • Zainularifeen Abduljaleel,
  • Abdellatif Bouazzaoui,
  • Neda M. Bogari,
  • Anas Dannoun and
  • Faisal A. Al-Allaf

11 July 2023

Background: Familial Hypercholesterolemia (FH) is a hereditary condition that causes a rise in blood cholesterol throughout a person’s life. FH can result in myocardial infarction and even sudden death if not treated. FH is thought to be caused...

(This article belongs to the Special Issue Omics Biology in Diagnosis of Diseases: Advances in Bioinformatics and Data Analyses)