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Search Results (11,106)

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31 pages, 11970 KB  
Article
Dynamic Trajectory Planning for Autonomous Parafoil Homing Under Wind Disturbances
by Luqi Yan, Yanguo Song, Huanjin Wang, Zhiwei Shi and Yilei Song
Aerospace 2026, 13(3), 276; https://doi.org/10.3390/aerospace13030276 (registering DOI) - 15 Mar 2026
Abstract
The parafoil is highly susceptible to deviations from its reference trajectory under wind disturbances. Given its constrained longitudinal control authority, it has limited capability to correct these deviations and regain the intended glide path. To overcome this limitation, we propose a dynamic planning [...] Read more.
The parafoil is highly susceptible to deviations from its reference trajectory under wind disturbances. Given its constrained longitudinal control authority, it has limited capability to correct these deviations and regain the intended glide path. To overcome this limitation, we propose a dynamic planning framework based on a layered homing strategy. The airdrop mission trajectory is initially designed as a traditional multi-segment path. To approximate non-uniform glide characteristics under wind disturbances, this planning problem incorporates a predicted wind model as an external input. Node parameters of the segmented trajectory are then solved using an improved grey wolf optimizer (IGWO). By tracking this reference trajectory, the parafoil is guided into the proximity of the target. To ensure landing precision, the terminal phase is formulated and discretized using an adaptive pseudo-spectral method (APSM). The online planner computes a real-time trajectory to account for actual motion characteristics. This dynamic replanning (DRP) compensates for deviations caused by model mismatches and external disturbances. The proposed homing method is statistically verified via extensive Monte Carlo simulations under different wind conditions. Finally, the airdrop experiment is conducted to validate the DRP method. Full article
(This article belongs to the Section Aeronautics)
29 pages, 2707 KB  
Review
Digital Twin Technology in Wind Turbine Condition Monitoring, Predictive Maintenance, and RUL Estimation: A Systematic Literature Review
by Jorge Maldonado-Correa, José Cuenca-Granda, Joel Torres-Cabrera, Galo Cerda Mejía, Wilson Daniel Bastidas Barragan, Rocío Guapulema, Edwin Paccha-Herrera, Juan Carlos Solano, Darwin Tapia-Peralta, José Benavides and Cristian Laverde-Albarracín
Energies 2026, 19(6), 1477; https://doi.org/10.3390/en19061477 (registering DOI) - 15 Mar 2026
Abstract
The rapid growth of wind energy has increased the need for advanced condition monitoring (CM), predictive maintenance, and remaining useful life (RUL) estimation strategies for wind turbines. In this context, digital twins (DTs) have emerged as a key tool for improving reliability, availability, [...] Read more.
The rapid growth of wind energy has increased the need for advanced condition monitoring (CM), predictive maintenance, and remaining useful life (RUL) estimation strategies for wind turbines. In this context, digital twins (DTs) have emerged as a key tool for improving reliability, availability, and operational efficiency by integrating physical models, operational data, and artificial intelligence (AI). This paper presents a systematic literature review (SLR) aimed at analyzing the state of the art, classifying the main applications, and identifying research gaps. A rigorous search protocol was applied across scientific databases, considering inclusion and exclusion criteria and analysis categories aligned with four research questions. The results show a high concentration of studies on critical wind turbine components, a predominance of hybrid physics-based and data-driven approaches, and an increasing use of deep learning (DL) models. However, several research gaps remain, including the predominance of component-level digital twin implementations rather than system-level architectures, the lack of standardized datasets and benchmarking frameworks, and challenges related to SCADA data heterogeneity and real-time scalability. It is concluded that DTs are evolving toward more autonomous and prescriptive systems; however, they still require further maturation for widespread industrial adoption. Full article
(This article belongs to the Special Issue Latest Challenges in Wind Turbine Maintenance, Operation, and Safety)
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17 pages, 3079 KB  
Article
AgroNova: An Autonomous IoT Platform for Greenhouse Climate Control
by Borislav Toskov and Asya Toskova
Sensors 2026, 26(6), 1861; https://doi.org/10.3390/s26061861 (registering DOI) - 15 Mar 2026
Abstract
This study presents AgroNova—a hybrid IoT architecture for autonomous monitoring and management of microclimate in greenhouse environments. The system combines a capillary wireless sensor network, gateway-level rule-based agents, a server agent, cloud services and an advisory component based on a large language model [...] Read more.
This study presents AgroNova—a hybrid IoT architecture for autonomous monitoring and management of microclimate in greenhouse environments. The system combines a capillary wireless sensor network, gateway-level rule-based agents, a server agent, cloud services and an advisory component based on a large language model (LLM) that supports local decision-making by incorporating external contextual information from meteorological services. The proposed architecture was validated through a seven-month deployment in an unheated tomato greenhouse, during which more than 380,000 environmental measurements were collected from five sensor nodes. The system operated continuously under real agricultural conditions, including during temporary internet connectivity interruptions, due to the autonomous gateway-level control and deterministic fallback mechanisms. The analysis of the collected data includes 3110 environmental threshold exceedance events, in which recovery dynamics, reaction latency, and actuator activation frequency were evaluated. The results show that the architecture supports stable autonomous operation under limited actuation conditions, with an average local reaction latency of less than 1 s, while physical actuator operations occur in approximately 2.3% of all control decisions. This behavior reflects a conservative control strategy that limits unnecessary mechanical operations and contributes to stable system operation. The experimental integration of a consultative LLM module within the server-side agent demonstrates the potential for context-enriched decision support using external meteorological data, while final control decisions remain under the authority of the gateway-based deterministic control mechanism. The main contribution of this study is the demonstration of a hybrid IoT architecture that combines edge-level autonomy with context-assisted reasoning, validated through deployment in a real greenhouse environment. Full article
(This article belongs to the Section Internet of Things)
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20 pages, 2758 KB  
Article
A Dynamic Risk Assessment System for Expressway Lane-Changing: Integrating Bayesian Networks and Markov Chains Under High-Density Traffic
by Quantao Yang and Peikun Li
Systems 2026, 14(3), 306; https://doi.org/10.3390/systems14030306 (registering DOI) - 15 Mar 2026
Abstract
In high-density expressway environments, lane-changing (LC) maneuvers act as stochastic perturbations that compromise the hydrodynamic stability of traffic flow, leading to safety hazards and operational delays. While existing literature has extensively modeled crash severity in static complex environments (e.g., tunnels and mountainous terrains), [...] Read more.
In high-density expressway environments, lane-changing (LC) maneuvers act as stochastic perturbations that compromise the hydrodynamic stability of traffic flow, leading to safety hazards and operational delays. While existing literature has extensively modeled crash severity in static complex environments (e.g., tunnels and mountainous terrains), there remains a critical deficiency in quantifying the dynamic, systemic risks induced by LC maneuvers under saturation conditions. To address this gap, this study proposes a novel Systemic Risk Assessment Framework. First, a Hidden Markov Model (HMM) is employed to decode the latent state transitions of following vehicles, quantifying the systemic consequence of LC maneuvers as “operational delay” based on traffic wave theory. Second, a Bayesian Network (BN) is constructed to infer the causal probability of risk, integrating geometric proxies such as insertion angle with kinematic variables. Validated with real-world trajectory data, the model achieves high accuracy in identifying risk accumulation precursors. This research contributes to the field of transportation systems by shifting the risk paradigm from static collision prediction to dynamic system reliability analysis, offering theoretical support for Connected and Autonomous Vehicle (CAV) decision logic. Full article
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23 pages, 5130 KB  
Article
YOLO Variant Evaluation and Transfer Learning Analysis for Side-Scan Sonar Object Detection
by Lei Liu, Houpu Li, Junhui Zhu, Ye Peng and Guojun Zhai
J. Mar. Sci. Eng. 2026, 14(6), 550; https://doi.org/10.3390/jmse14060550 (registering DOI) - 15 Mar 2026
Abstract
Side-scan sonar is essential to underwater target detection, yet its effectiveness is hindered by scarce annotated data and complex acoustic artifacts. This study systematically evaluates four YOLO variants, YOLOv8n, YOLOv10n, YOLOv11n, and the newly released YOLOv13n, on two public side-scan sonar datasets with [...] Read more.
Side-scan sonar is essential to underwater target detection, yet its effectiveness is hindered by scarce annotated data and complex acoustic artifacts. This study systematically evaluates four YOLO variants, YOLOv8n, YOLOv10n, YOLOv11n, and the newly released YOLOv13n, on two public side-scan sonar datasets with limited samples and severe class imbalance. We assess detection accuracy, computational efficiency, inference speed, and transfer learning using COCO pre-trained weights, as well as the impact of optimizer choice between SGD and AdamW. The results reveal distinct strengths: YOLOv8n achieves the fastest inference at 60.98 FPS, with a competitive mAP50 of 0.906, ideal for real-time applications. YOLOv11n offers the best accuracy–efficiency balance, attaining the highest recall of 0.859 and mAP50 of 0.917. YOLOv13n demonstrates exceptional precision of 0.993 and high-IoU localization, with an mAP75 of 0.760. Transfer learning consistently boosts performance, with average mAP50:95 gains exceeding 54% on the more challenging dataset, highlighting its critical role in overcoming data scarcity. SGD generally outperforms AdamW, confirming its suitability as the default optimizer. These findings provide practical guidelines: YOLOv8 for real-time needs, YOLOv11 for balanced performance, and YOLOv13 for precision-critical tasks with ample resources. This work also establishes a benchmark for future underwater autonomous system research. Full article
(This article belongs to the Section Ocean Engineering)
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15 pages, 276 KB  
Article
Assessment of Autonomic Nervous System Function in Patients with Aortic Stenosis and Diabetes Mellitus
by Mihajlo Farkić, Nikola Marković, Valentina Balint, Maša Petrović, Milovan Bojić and Branislav Milovanović
Diagnostics 2026, 16(6), 871; https://doi.org/10.3390/diagnostics16060871 (registering DOI) - 15 Mar 2026
Abstract
Background/Objectives: Aortic stenosis is associated with autonomic nervous system (ANS) imbalance, while diabetes mellitus is a major contributor to cardiac autonomic neuropathy. Their coexistence may result in more pronounced autonomic dysfunction not fully captured by conventional assessment. This study aimed to compare ANS [...] Read more.
Background/Objectives: Aortic stenosis is associated with autonomic nervous system (ANS) imbalance, while diabetes mellitus is a major contributor to cardiac autonomic neuropathy. Their coexistence may result in more pronounced autonomic dysfunction not fully captured by conventional assessment. This study aimed to compare ANS function in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR), according to diabetes status. Methods: This cross-sectional study included 74 patients with severe aortic stenosis referred for TAVR, including 21 patients with diabetes mellitus. Autonomic function was evaluated using non-invasive ECG-based analysis, incorporating short-term and 24 h Holter-derived heart rate variability (HRV), nonlinear Poincaré plot indices, and deceleration and acceleration capacity. Ambulatory blood pressure monitoring and standard clinical and echocardiographic assessment were performed. Results: Patients with diabetes mellitus demonstrated significantly lower long-term HRV parameters and reduced nonlinear Poincaré plot indices compared with non-diabetic patients, indicating altered autonomic modulation. Short-term HRV showed similar trends without statistical significance. Echocardiographic severity of aortic stenosis and left ventricular systolic function were comparable between groups. Conclusions: Autonomic dysfunction appears to be more pronounced in patients with severe aortic stenosis and diabetes mellitus, predominantly affecting parasympathetic modulation. ECG-derived autonomic parameters may offer complementary insight into ANS involvement in this population and warrant further investigation. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
28 pages, 2882 KB  
Article
Semantic Divergence in AI-Generated and Human Influencer Product Recommendations: A Computational Analysis of Dual-Agent Communication in Social Commerce
by Woo-Chul Lee, Jang-Suk Lee and Jungho Suh
Appl. Sci. 2026, 16(6), 2816; https://doi.org/10.3390/app16062816 (registering DOI) - 15 Mar 2026
Abstract
The proliferation of generative artificial intelligence (AI) as an autonomous recommendation agent fundamentally challenges traditional paradigms of marketing communication. As AI systems increasingly mediate consumer–brand relationships, understanding how artificial agents construct persuasive discourse—distinct from human communicators—becomes critical for developing effective dual-channel marketing strategies. [...] Read more.
The proliferation of generative artificial intelligence (AI) as an autonomous recommendation agent fundamentally challenges traditional paradigms of marketing communication. As AI systems increasingly mediate consumer–brand relationships, understanding how artificial agents construct persuasive discourse—distinct from human communicators—becomes critical for developing effective dual-channel marketing strategies. Grounded in Source Credibility Theory and the Computers Are Social Actors (CASA) paradigm, this study investigates the semantic and structural divergence between AI-generated product recommendations and human influencer marketing messages in social commerce contexts. Employing a mixed-methods computational approach integrating term frequency analysis, TF-IDF weighting, Latent Dirichlet Allocation (LDA) topic modeling, and BERT-based contextualized semantic embedding analysis (KR-SBERT), we examined 330 Instagram influencer posts and 541 AI-generated responses concerning inner beauty enzyme products—a hybrid category combining functional health claims with hedonic beauty appeals—in the Korean social commerce market. AI-generated responses were collected through a systematically designed query protocol with empirically grounded prompts derived from actual consumer search behaviors, and analytical robustness was verified through sensitivity analyses across multiple parameter thresholds. Our findings reveal a fundamental divergence in persuasive architecture: human influencers construct experiential narratives exhibiting message characteristics typically associated with peripheral-route cues (sensory descriptions, emotional testimonials, social context), while AI recommendations employ systematic, evidence-based discourse exhibiting message characteristics typically associated with central-route argumentation (functional mechanisms, ingredient specifications, objective criteria). Topic modeling identified four distinct thematic clusters for each source type: human discourse centers on embodied experience and relational consumption, whereas AI discourse organizes around informational utility and rational decision support. Jensen–Shannon Divergence analysis (JSD = 0.213 bits) confirmed moderate distributional divergence, while chi-square testing (χ2 = 847.23, p < 0.001) and Cramér’s V (0.312, indicating a medium-to-large effect) demonstrated statistically significant and substantively meaningful differences. These findings extend CASA theory by demonstrating that AI recommendation agents develop a characteristic “AI communication signature” distinguishable from human persuasion patterns. We propose an integrated Dual-Agent Persuasion Proposition—synthesizing CASA, ELM, and Source Credibility perspectives—suggesting that AI and human recommenders serve complementary functions across different stages of the consumer decision journey—a proposition whose predictions regarding sequential persuasive effectiveness and consumer processing routes await experimental validation. These findings carry implications for AI content strategy optimization, platform design, and emerging regulatory frameworks for AI-generated content labeling. Full article
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23 pages, 6668 KB  
Article
Development of a Visual SLAM-Based Autonomous UAV System for Greenhouse Plant Monitoring
by Jing-Heng Lin and Ta-Te Lin
Drones 2026, 10(3), 205; https://doi.org/10.3390/drones10030205 (registering DOI) - 15 Mar 2026
Abstract
Autonomous monitoring is essential for precision agriculture in greenhouses, yet deploying unmanned aerial vehicles (UAVs) in confined, GPS-denied environments remains limited by payload, power, and cost constraints. This study developed and validated an autonomous UAV system for reliable, low-cost operation in such conditions. [...] Read more.
Autonomous monitoring is essential for precision agriculture in greenhouses, yet deploying unmanned aerial vehicles (UAVs) in confined, GPS-denied environments remains limited by payload, power, and cost constraints. This study developed and validated an autonomous UAV system for reliable, low-cost operation in such conditions. The proposed system employs a dual-link edge-computing architecture: a lightweight onboard controller handles flight control and sensor acquisition, while visual simultaneous localization and mapping (V-SLAM) is offloaded to an edge computer via the FPV video link. Phenotyping (flower detection and tracking/counting) is performed offline from the side-view RGB stream and does not participate in the flight control loop. Using muskmelon (Cucumis melo L.) flower development as a case study, the UAV autonomously executed daily missions for 27 days in a commercial greenhouse, performing flower detection and tracking to monitor phenological dynamics. Localization and control accuracy were evaluated against a validated UWB reference system, achieving 5.4~8.0 cm 2D RMSE for trajectory tracking and 12.7 cm translation RMSE for greenhouse mapping. This work demonstrates a practical architecture for autonomous monitoring in GPS-denied agricultural environments, with operational boundaries characterized through the sustained field deployment. The system’s design principles may extend to other indoor or communication-limited scenarios requiring lightweight, intelligent robotic operation. Full article
(This article belongs to the Section Drones in Agriculture and Forestry)
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16 pages, 752 KB  
Review
Safety-First Framework for AI-Enabled Anamnesis in Head and Neck Surgery: Evidence Synthesis from a Narrative Review
by Luigi Angelo Vaira, Hareem Qadeer, Jerome R. Lechien, Antonino Maniaci, Fabio Maglitto, Stefania Troise, Carlos M. Chiesa-Estomba, Giuseppe Consorti, Giulio Cirignaco, Giannicola Iannella, Carlos Navarro-Cuéllar, Giovanni Salzano, Giovanni Maria Soro, Paolo Boscolo-Rizzo, Valentino Vellone and Giacomo De Riu
J. Clin. Med. 2026, 15(6), 2218; https://doi.org/10.3390/jcm15062218 (registering DOI) - 14 Mar 2026
Abstract
Objectives: To synthesize evidence on artificial intelligence (AI)-enabled medical history taking (anamnesis)—beyond large language models (LLMs) alone—and to translate findings into implications and research priorities for head and neck surgery. Methods: We performed a PRISMA-informed narrative review. Searches from database inception [...] Read more.
Objectives: To synthesize evidence on artificial intelligence (AI)-enabled medical history taking (anamnesis)—beyond large language models (LLMs) alone—and to translate findings into implications and research priorities for head and neck surgery. Methods: We performed a PRISMA-informed narrative review. Searches from database inception to 31 December 2025 (updated 3 January 2026) were conducted in MEDLINE (PubMed), Embase, Scopus, Web of Science Core Collection, IEEE Xplore, and ACM Digital Library, supplemented by medRxiv/arXiv screening and citation chasing. We included studies evaluating or describing AI-supported history capture/summarization, conversational interviewing, symptom checker/digital triage, EHR-integrated intake-to-decision support pipelines, voice interviewing, education/training systems, and governance/ethical considerations related to digital anamnesis. Findings were synthesized by system category and by cross-cutting outcome domains, with a head and neck surgery interpretive lens. Results: Fifty studies (2014–2025) were included. Evidence most consistently suggested feasibility and acceptability of pre-consultation computer-assisted history taking and the potential to reduce documentation burden and improve structured capture. In contrast, symptom checkers and digital triage tools showed highly variable diagnostic/triage performance and prominent safety concerns, highlighting the importance of conservative red-flag escalation strategies, continuous monitoring, and clear accountability. LLM-based diagnostic dialogue demonstrated strong performance in controlled evaluations, but prospective real-world validation, governance, and workflow integration remain limited. Conclusions: AI-enabled anamnesis comprises heterogeneous tools with uneven evidence. For head and neck surgery, potential near-term applications may include structured pre-visit intake, clinician-facing summarization, and training applications, whereas autonomous triage warrants harm-oriented, specialty-calibrated validation and robust governance prior to broader clinical reliance. Full article
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27 pages, 16385 KB  
Article
High-Precision Time Synchronization and Autonomous Maintenance for LEO Satellite Constellations Based on High-Stability Crystal Oscillators
by Lei Mu, Xiaogong Hu, Mengjie Wu and Jin Li
Sensors 2026, 26(6), 1839; https://doi.org/10.3390/s26061839 (registering DOI) - 14 Mar 2026
Abstract
In recent years, the large-scale deployment of Low Earth Orbit (LEO) constellations has made autonomous time synchronization and reference maintenance within constellations a critical enabling technology. Achieving high-precision synchronization with low cost and low power consumption, without relying on onboard atomic clocks or [...] Read more.
In recent years, the large-scale deployment of Low Earth Orbit (LEO) constellations has made autonomous time synchronization and reference maintenance within constellations a critical enabling technology. Achieving high-precision synchronization with low cost and low power consumption, without relying on onboard atomic clocks or Global Navigation Satellite System (GNSS) signals, remains a significant challenge. This paper proposes an autonomous time synchronization method for LEO constellations that relies solely on high-stability crystal oscillators as local oscillators. By leveraging satellite-to-ground and inter-satellite measurement links, the proposed approach enables constellation-wide time synchronization without external timing references.A satellite-to-ground link visibility time model is established based on orbital parameters and ground station visibility geometry. On this basis, a discrete state-space model is constructed, incorporating temperature-induced frequency perturbation compensation, frequency offset estimation, and control voltage regulation. A combined Kalman filtering and Linear Quadratic Regulator (LQR) control framework is employed to achieve precise time offset synchronization and long-term maintenance. Experimental results demonstrate that, under a Walker-Delta constellation configuration with an orbital altitude of 800 km and an inclination of 55,the proposed method introduces a time synchronization performance better than 5 ns (1σ), with a peak-to-peak error below 30 ns. This level of performance satisfies the timing requirements of typical LEO constellation applications, including communication scheduling, high-rate modulation, and critical infrastructure timing services. Moreover, the proposed scheme supports decentralized deployment and provides local physical time signal outputs, making it well suited for large-scale satellite networks requiring high-precision autonomous time synchronization. Full article
(This article belongs to the Section Remote Sensors)
39 pages, 13943 KB  
Article
Characterizing Initial Cervical Spine and Neurovascular Findings in 84 Consecutive Patients with Hypermobile Ehlers–Danlos Syndrome: A Retrospective Study
by Ross A. Hauser, Morgan Griffiths, Ashley Watterson, Danielle Matias and Benjamin R. Rawlings
J. Clin. Med. 2026, 15(6), 2212; https://doi.org/10.3390/jcm15062212 (registering DOI) - 14 Mar 2026
Abstract
Background: Hypermobile Ehlers–Danlos syndrome (hEDS) can present as a complex interplay of widespread symptomatology and multisystem involvement, posing diagnostic and treatment challenges. Objective characterization of cervical spine and neurovascular findings in hEDS has been limited. Previous studies have emphasized upper cervical spine [...] Read more.
Background: Hypermobile Ehlers–Danlos syndrome (hEDS) can present as a complex interplay of widespread symptomatology and multisystem involvement, posing diagnostic and treatment challenges. Objective characterization of cervical spine and neurovascular findings in hEDS has been limited. Previous studies have emphasized upper cervical spine complications in hEDS, yet the relevance and mechanisms underlying associated symptomatology have not been elucidated. This study examined objective test findings in patients with hEDS at an outpatient neck clinic to explore cervical spine and neurovascular pathology that could contribute to further understanding the clinical profile of a subset of patients with hEDS. Methods: This single-center, retrospective observational study included patients with hEDS aged 20–50 years from 1 January 2022–31 December 2024, at an outpatient neck center. It excluded previous neck surgery, traumatic events, or related injury. Demographic, clinical, and diagnostic data were collected through a retrospective chart review, including measurements from standard clinical diagnostic protocols: digital motion X-ray (videofluoroscopy), cone beam CT, Doppler ultrasound, and tonometry. Results: More than 71% of patients reported ≥29 symptoms. Nearly all patients exhibited co-occurring forward head, decreased depth of curve, ligamentous cervical instability, and decreased internal jugular vein (IJV) and vagus nerve cross-sectional area (CSA). Vagus nerve CSA was found to be significantly smaller than the comparative healthy/normal population. IJV CSA was significantly smaller at C1 than at C4–C5, suggesting evidence of carotid sheath compression at C1. Conclusions: This study offers novel evidence that cervical spine pathology, IJV compression, and vagus nerve degeneration are uniformly prevalent in hEDS, which may contribute to, or be an etiological basis for, the multisystem involvement in a subset of patients with this disorder. These findings provide hypothesis-generating data to inform future mechanistic and therapeutic studies, including exploration of new diagnostic and treatment targets. Full article
(This article belongs to the Special Issue Clinical Advances in Musculoskeletal Disorders: 2nd Edition)
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17 pages, 602 KB  
Review
Artificial Intelligence Applications in Gastric Cancer Surgery: Bridging Early Diagnosis and Responsible Precision Medicine
by Silvia Malerba, Miljana Vladimirov, Aman Goyal, Audrius Dulskas, Augustinas Baušys, Tomasz Cwalinski, Sergii Girnyi, Jaroslaw Skokowski, Ruslan Duka, Robert Molchanov, Bojan Jovanovic, Francesco Antonio Ciarleglio, Alberto Brolese, Kebebe Bekele Gonfa, Abdi Tesemma Demmo, Zilvinas Dambrauskas, Adolfo Pérez Bonet, Mario Testini, Francesco Paolo Prete, Valentin Calu, Natale Calomino, Vikas Jain, Aleksandar Karamarkovic, Karol Polom, Adel Abou-Mrad, Rodolfo J. Oviedo, Yogesh Vashist and Luigi Maranoadd Show full author list remove Hide full author list
J. Clin. Med. 2026, 15(6), 2208; https://doi.org/10.3390/jcm15062208 - 13 Mar 2026
Abstract
Background: Artificial intelligence is emerging as a promising tool in surgical oncology, with growing evidence suggesting potential applications in diagnostic support, intraoperative guidance, and perioperative risk assessment. In gastric cancer surgery, emerging applications range from AI-assisted endoscopic detection to data-driven perioperative risk [...] Read more.
Background: Artificial intelligence is emerging as a promising tool in surgical oncology, with growing evidence suggesting potential applications in diagnostic support, intraoperative guidance, and perioperative risk assessment. In gastric cancer surgery, emerging applications range from AI-assisted endoscopic detection to data-driven perioperative risk prediction, while some technological developments, particularly in robotic autonomy, derive from broader surgical or experimental models that may inform future gastric procedures. Methods: A narrative review was conducted following established methodological standards, including the Scale for the Assessment of Narrative Review Articles (SANRA) and the Search–Appraisal–Synthesis–Analysis (SALSA) framework. English-language studies indexed in PubMed, Scopus, Embase, and Web of Science up to October 2025 were included. Evidence was synthesized thematically across five domains: AI-assisted anatomical recognition and lymphadenectomy support, autonomous robotic systems, early cancer detection, perioperative predictive and frailty models, and ethical and regulatory considerations. Results: AI-based computer vision and deep learning algorithms have demonstrated promising capabilities for real-time anatomical recognition, surgical phase classification, and intraoperative guidance, although evidence of direct patient-level benefit remains limited. In diagnostic settings, AI-assisted endoscopy and Raman spectroscopy have been shown to improve early lesion detection and reduce dependence on operator experience. Predictive models, including MySurgeryRisk and AI-driven frailty assessments, may support individualized prehabilitation planning and perioperative risk stratification. Persistent limitations include small and heterogeneous datasets, insufficient external validation, and unresolved concerns related to data privacy, algorithmic interpretability, and medico-legal responsibility. Conclusions: Artificial intelligence is progressively emerging as a promising tool in gastric cancer surgery, integrating automation, advanced analytics, and human clinical reasoning. Its safe and ethical adoption requires robust validation, transparent governance, and continuous surgeon oversight. When developed within human-centered and ethically grounded frameworks, AI can augment, rather than replace, surgical expertise, potentially advancing precision, safety, and equity in oncologic care. Full article
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17 pages, 1093 KB  
Article
Concomitant Dysregulation of Cerebral Vasoreactivity and Arterial Blood Pressure Is Closely Related in Patients with Carotid Stenosis
by Hanga Pál, Rita Magyar-Stang, Borbála Csányi, Anna Gaál, Zsuzsanna Mihály, Zsófia Czinege, Péter Sótonyi, Tamás Horváth, Balázs Dobi, Dániel Bereczki, Akos Koller and Róbert Debreczeni
Life 2026, 16(3), 472; https://doi.org/10.3390/life16030472 - 13 Mar 2026
Abstract
Background: In patients with severe atherosclerotic internal carotid artery stenosis (ICAS), the capacity of cerebral vasoreactivity (CVR)—an independent risk factor for cerebral ischemia—is reduced, and dysregulation of arterial blood pressure (ABP) may also be present. Thus, this study assessed the relationship between changes [...] Read more.
Background: In patients with severe atherosclerotic internal carotid artery stenosis (ICAS), the capacity of cerebral vasoreactivity (CVR)—an independent risk factor for cerebral ischemia—is reduced, and dysregulation of arterial blood pressure (ABP) may also be present. Thus, this study assessed the relationship between changes in cerebral blood flow velocity (BFV) in response to vasoactive stimuli (as measured by transcranial Doppler (TCD)), characterizing CVR and cardiovascular autonomic nervous system (CANS) function. Methods: Common carotid artery compression (CCC n = 26), hyperventilation (HV) and breath-holding (BH) tests (n = 31), and the Valsalva maneuver (VM n = 34) were used to assess CVR in patients with ICAS. In the middle cerebral arteries, BFV was monitored by TCD, whereas ABP was registered non-invasively. For statistical analysis, validated indices describing CANS function—namely, sympathetic index (SI), pressure recovery time (PRT), and Valsalva heart rate ratio (VHRR)—were selected based on the VM response. Several parameters were defined in order to evaluate CVR responses, including cerebral arterial resistance (CAR = ABP/BFV), which was correlated with the CVR indices using Spearman’s pairwise correlation and canonical correlation. Results: A significant correlation was found between several CVR indices of the HV-BH and VM tests and CANS indices of VM using Spearman’s pairwise correlation test. Regarding the HV-BH CVR and CANS indices of VM, a significant correlation was found between CAR values until it reached its maximum on the to-be-operated side (CARtimetomaxICAop) and VHRR (p = 0.041). A significant correlation was also found between the time elapsed until the CAR minimum value (CARtimetominICAop) and SI (p = 0.019). Concerning the CVR and CANS indices of the VM, a significant correlation was found between cerebrovascular Valsalva ratio on the to-be-operated side (CVARICAop) and PRT (p = 0.002). Canonical correlation analysis confirmed that impairments of CANS and CVR may be associated. Conclusions: In patients with severe ICAS, the potentially concomitant dysregulation of cerebrovascular reactivity and the cardiovascular autonomic nervous system can further increase cerebral ischemic risk. Full article
(This article belongs to the Section Medical Research)
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17 pages, 567 KB  
Review
Treating the Patient, Not Only the Amyloid: Symptomatic Management in Transthyretin Amyloidosis
by Christian Messina
Neurol. Int. 2026, 18(3), 53; https://doi.org/10.3390/neurolint18030053 - 13 Mar 2026
Abstract
Transthyretin amyloidosis (ATTR) is a progressive multisystem disorder characterized by extracellular deposition of misfolded transthyretin fibrils, leading to neurological, cardiac, gastrointestinal, urogenital, sexual, and ophthalmological involvement. While disease-modifying therapies have significantly improved survival and slowed disease progression, a substantial proportion of patients continue [...] Read more.
Transthyretin amyloidosis (ATTR) is a progressive multisystem disorder characterized by extracellular deposition of misfolded transthyretin fibrils, leading to neurological, cardiac, gastrointestinal, urogenital, sexual, and ophthalmological involvement. While disease-modifying therapies have significantly improved survival and slowed disease progression, a substantial proportion of patients continue to experience a high symptomatic burden that markedly impairs quality of life. Symptomatic manifestations often occur early, may precede the diagnosis, and frequently persist despite etiological treatment. This review provides a comprehensive overview of the symptomatic management of ATTR, with particular emphasis on autonomic dysfunction and its systemic consequences. We discuss current therapeutic strategies for orthostatic hypotension, gastrointestinal dysmotility, nutritional impairment, sexual dysfunction, lower urinary tract dysfunction, and ophthalmological involvement, highlighting both pharmacological and non-pharmacological approaches. Special attention is given to treatment limitations related to cardiac involvement, autonomic failure, and drug tolerability. Despite the clinical relevance of symptom control in ATTR, evidence-based recommendations remain scarce, and no dedicated guidelines currently exist. Most therapeutic approaches are derived from observational studies, expert opinion, and clinical experience. Improved awareness of symptomatic manifestations, early intervention, and a multidisciplinary, individualized approach are essential to optimize patient outcomes. Future research should focus on prospective studies and the development of structured symptomatic treatment algorithms to complement disease-modifying therapies and enhance patient-centered care in ATTR. Full article
(This article belongs to the Topic Dysautonomia in Neurological Disorders)
17 pages, 1708 KB  
Article
Robust Visual–Inertial SLAM and Biomass Assessment for AUVs in Marine Ranching
by Yangyang Wang, Ziyu Liu, Tianzhu Gao and Xijun Du
Symmetry 2026, 18(3), 495; https://doi.org/10.3390/sym18030495 - 13 Mar 2026
Abstract
Environmental perception is a cornerstone for autonomous underwater vehicles (AUVs) to achieve robust self-localization and scene understanding, which are pivotal for the intelligent management of marine ranching. However, underwater image degradation and weak-textured scenes significantly hinder reliable self-localization and fine-grained environmental perception. To [...] Read more.
Environmental perception is a cornerstone for autonomous underwater vehicles (AUVs) to achieve robust self-localization and scene understanding, which are pivotal for the intelligent management of marine ranching. However, underwater image degradation and weak-textured scenes significantly hinder reliable self-localization and fine-grained environmental perception. To address the perceptual asymmetry arising from these challenges, this paper proposes a robust visual–inertial simultaneous localization and mapping (SLAM) and biomass assessment scheme for marine ranching. Specifically, we first propose a robust tightly coupled underwater visual–inertial localization scheme, which leverages a multi-sensor fusion strategy to solve the image degradation problem of localization in complex underwater environments. Furthermore, we propose a novel underwater scene perception method, which enables the simultaneous visual reconstruction of aquaculture species and the quantitative mapping of their spatial distribution in marine ranching. Finally, we develop a low-cost, agile, and portable multisensor-integrated system that consolidates autonomous localization and aquaculture biomass assessment modules, with its performance validated through extensive real-world underwater experiments. The experimental results demonstrate that the proposed methods can effectively overcome the interference of complex underwater environments and provide high-precision perception support for both AUV state estimation and aquaculture asset management. Full article
(This article belongs to the Special Issue Symmetry in Next-Generation Intelligent Information Technologies)
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