Search Results (24,526)

The sustainable development of university safety governance is an important component of the national security management system and also serves as a fundamental safeguard for protecting the life and health of students and staff on campus. The improvement of university safety risk governance relies on analyzing the identification of various safety risks and maintaining an effective crisis management process for potential sudden safety risks. The 24Model and the 4R model have respectively demonstrated strong analytical advantages in the fields of accident causation analysis and emergency crisis management; however, few studies have examined the internal relationship between them. This study attempts to integrate the 24Model and the 4R crisis management framework to propose and analyze a 2-4-4R model for university safety risk management. Through a case study, the model is applied to analyze a laboratory explosion accident at a university. The results show that the risk factors leading to campus safety accidents can be analyzed from four aspects: safety culture, safety management system, individual factors, and unsafe acts and physical conditions. University safety management should comprehensively identify these four types of factors and propose governance measures sequentially from the four stages of reduction, readiness, response, and recovery in order to improve safety management capacity. The case analysis confirms that the 2-4-4R model has applicability and practical value in the identification and governance analysis of university safety risks. It provides a systematic research perspective for the identification and management of safety risks in universities, and is of great significance for promoting the sustainable development of universities. Full article

Non-destructive and destructive test methods are applied to wood to characterize this heterogeneous natural material. There have been multiple studies to characterize and investigate the change after the treatment (impregnation, thermal modification, etc.). In terms of thermal modification, there have been few studies on thermo–vacuum treatment, which is performed in a continuous vacuum atmosphere. With this method, the objective was to attempt to reduce the strength decrease after the thermal treatment. The aim of this study was to estimate the flexural properties of thermo–vacuum-treated Scots pine wood with destructive and acoustic-based non-destructive test methods. Wood was treated at 180 °C and 360 mm Hg. Both treated and untreated samples were cut into small specimens to ensure they were free of defects and were tested with acoustic-based non-destructive (longitudinal vibration and stress wave) and static bending test methods. The results show a decrease in equilibrium moisture content, demonstrating the efficiency of the treatment. When the results were compared with destructive test results, higher correlations (R² > 0.858) were found when estimating the modulus of elasticity (MOE) for both the untreated and treated wood, while lower correlations (R² < 0.440) were found for the modulus of rupture (MOR). When an additional equation was developed, stronger correlations (R² > 0.8986) were obtained between the non-destructive and destructive test results. Full article

Oblivious Transfer (OT) is a fundamental cryptographic primitive for privacy-preserving data exchange. While traditional OT protocols guarantee unconditional receiver anonymity, they inherently lack the mechanisms to prevent abusive mass data harvesting. Traceable Oblivious Transfer (TOT) addresses this by introducing “conditional anonymity,” revoking the privacy of malicious users. However, existing TOT mechanisms either rely on computationally expensive dynamic assumptions or require continuous interaction with a Trusted Third Party (TTP) to manage credentials. To overcome these limitations, we present an Identity-Based Traceable Oblivious Transfer (IB-TOT) protocol. By synergizing polynomial-based secret sharing with Blind Identity-Based Encryption (Blind IBE), our scheme completely eliminates the TTP during the data transfer stage. The Blind IBE extraction algorithm serves as the primary oblivious channel, utilizing data indices as user identities. We strictly bound the receiver’s query quota by embedding a degree-k tracing polynomial directly into the key issuance phase. Honest clients enjoy fully protected retrieval of up to k items, whereas any attempt to exceed this quota deterministically exposes the violator’s identity. Comprehensive security proofs demonstrate that IB-TOT satisfies sender privacy, receiver privacy, and strict accountability under standard static assumptions (DBDH and DL). Full article

Future 6G-enabled smart hospital infrastructures will support latency-critical medical operations such as robotic surgery, autonomous monitoring, and real-time clinical decision systems, which require communication mechanisms that ensure both ultra-low latency and long-term cryptographic security. Existing security solutions either rely on classical cryptographic protocols that are vulnerable to quantum attacks or deploy isolated post-quantum primitives without providing a unified framework for secure real-time medical command transmission. This research presents a latency-aware, multi-layered post-quantum security architecture for 6G-enabled smart hospital environments. The proposed framework establishes an end-to-end secure command transmission pipeline that integrates hardware-rooted device authentication, post-quantum key establishment, hybrid payload protection, dynamic access enforcement, and tamper-evident auditing within a coherent system design. In contrast to existing approaches that focus on individual security mechanisms, the architecture introduces a structured integration of Kyber-based key encapsulation and Dilithium digital signatures with hybrid AES-based encryption and legacy-compatible key transport, while Physical Unclonable Function authentication provides hardware-bound device identity verification. Zero Trust access control, metadata-driven anomaly detection, and blockchain-style audit logging provide continuous verification and traceability, while threshold cryptography distributes cryptographic authority to eliminate single points of compromise. The proposed architecture is evaluated using a discrete-event simulation framework representing adversarial conditions in realistic 6G medical communication scenarios, including replay attacks, payload manipulation, and key corruption attempts. Experimental results demonstrate improved security and operational efficiency, achieving a 48% reduction in detection latency, a 68% reduction in false-positive anomaly detection rate, and a 39% improvement in end-to-end round-trip latency compared to conventional RSA-AES-based architectures. These results demonstrate that the proposed framework provides a practical and scalable approach for achieving post-quantum secure and low-latency command transmission in next-generation 6G smart hospital systems. Full article

The silkworm, Bombyx mori (Bm), is an insect that contributes to industries such as silk production, cosmetics, medicine, and food, as well as to scientific research. A previous study showed that Bm odorant receptor (BmOr) genes, BmOr44, BmOr54, and BmOr63, may play a major role in oviposition. This research aimed to investigate the function of these three genes using a double-stranded RNA (dsRNA) technique to knock down their expression levels. Our results revealed that the gene-specific dsRNAs could moderately reduce the expression levels of BmOr44, BmOr54, and BmOr63 in the silk moth antenna. Silk moths were injected with 50 nM dsRNABmOr54 and 100 nM dsRNABmOr63 and showed relative oviposition rates under the mulberry leaves condition at 111.45% and 109.58%, respectively, when compared to those with dsRNAlacZ injection. The reduction in expression levels of these three genes showed no effect on the oviposition rates of the silk moths without mulberry leaves treatment. The expression levels of these BmOr genes were restored after fertilization, suggesting the temporary effects of the dsRNAs. Our findings suggested that variation in BmOr54 expression level was correlated with changes in oviposition behavior in Bombyx mori. Full article

Although plant restoration is essential for improving soil structure and stability, there are still few systematic assessments of its impacts across various restored vegetation species, especially in environmentally sensitive areas like the East Qinling Mountains. In order to provide a scientific foundation for optimizing restoration tactics and enhancing soil erosion control and ecosystem services in the area, this study attempts to assess the impacts of different recovered plant types on soil aggregate stability and to clarify the underlying mechanisms. The Pinus tabuliformis Carrière, Quercus variabilis Blume, Robinia pseudoacacia L., Pinus tabulaeformis-Quercus variabilis mixed forest, Platycladus orientalis (L.) Franco and abandoned grassland were the six vegetation types represented by the sixteen plots. Farmland was used as a control. Soil samples were taken from three depths (0–5 cm, 5–20 cm, and 20–40 cm) and evaluated for root biomass, soil organic matter (SOM), and water-stable aggregate dispersion. Mean weight diameter (MWD), fractal dimension (D), macroaggregate content of diameter > 0.25 mm (R_0.25), and percentage of aggregate disruption (PAD) were used to evaluate aggregate stability. One-way ANOVA, LSD multiple comparisons, and Spearman correlation analysis were among the statistical analyses. In comparison to grassland and farming, forested regions, particularly mixed forests, showed considerably higher proportions of macroaggregates (>0.25 mm) and superior aggregate stability (higher MWD and R_0.25, lower D and PAD). Increased litter and coarse root inputs, which encouraged big water-stable aggregates (WSAs) and reinforced their positive connection with SOM, were the driving forces behind this development. Robinia pseudoacacia L. and Platycladus orientalis (L.) Franco displayed the highest SOM concentration and root biomass (1201.45 and 679.66 g/m², respectively). At all depths, mixed forests showed the most stable soil structure. In contrast to agriculture, vegetation restoration dramatically changed the mechanical composition of the soil, increasing the differentiation of particle-size fractions across soil layers and decreasing the amount of surface clay. Soil aggregate stability is greatly enhanced by vegetation restoration, with mixed forests offering the greatest advantages because of their varied root systems and increased input of organic matter. These results emphasize how crucial it is to choose the right vegetation types for restoration efforts in order to improve soil structure, reduce erosion, and promote ecological sustainability in the East Qinling Mountains. Full article

Objective: Feeding-tube weaning is conducted in both inpatient and outpatient settings, with significant logistical, financial, and structural barriers to both approaches. We sought to assess whether remote patient monitoring (RPM), using a mobile application, which would overcome many of these barriers, could be effective in helping patients tube wean. Methods: We prospectively enrolled patients with a feeding tube, aged 0–3 years. Enrolled families entered data daily into the remote application. Data were monitored by a nurse and reviewed weekly by a multidisciplinary team. A standard hunger provocation protocol was used, paired with medical, behavioral, oral motor, and nutrition interventions, as needed. We conducted a retrospective chart review to identify a comparison cohort. The chart review was collected first, then compared to the prospective, non-randomized trial of RPM tube weaning. Results: The chart review identified 141 children seen with a feeding tube from January 2023–June 2023. Of those, 17 children attempted a tube wean. The post-intervention group consisted of 38 children prospectively enrolled from the same clinic between November 2023–2024. In the pre-intervention group, 41% of the children (7/17) were successful in achieving all calories by mouth and 90% of children (34/38) in the post-intervention group were successful in tube weaning. Conclusions: RPM is a feasible and incredibly promising model for feeding-tube weaning in pediatric patients with a wide range of medical comorbidities, including patients with multiple comorbidities. RPM allowed for high-quality medical monitoring and for a dynamic intervention in response to patient data transferred to the medical team in real time. Full article

Background: Major depressive disorder (MDD) is a common mental disorder characterized by a wide range of symptoms and a substantial contribution to global disease burden. Our study aimed to examine the relationships between childhood trauma, sleep quality, dissociative symptoms, posttraumatic growth, and suicidality in patients diagnosed with MDD. Methods: Our sample consisted of 115 patients with MDD and 84 healthy controls. Participants were administered the Hamilton Depression Rating Scale (HDRS), Beck Scale for Suicidal Ideation (BSSI), Pittsburgh Sleep Quality Index (PSQI), Childhood Trauma Questionnaire (CTQ-33), Dissociative Experiences Scale (DES), and Posttraumatic Growth Inventory (PTGI). Group differences were analyzed, and associations among variables within the MDD group were examined using correlation and mediation analyses. Results: Compared to healthy controls, patients with MDD had significantly higher scores on all scales except the PTGI (p < 0.001 for each). Within the MDD group, individuals with a history of suicide attempts had significantly higher CTQ total scores, physical and sexual abuse subscale scores, and DES scores than those without previous attempts. Additionally, dissociative experiences had a partial mediating role in the relationship between depression severity and suicidal ideation, as well as in the relationship between childhood traumas and sleep quality. Conclusions: The findings highlight the clinical relevance of dissociative experiences and sleep disturbances in the heterogeneous presentation of MDD and their association with illness severity and suicidality. In the follow-up and treatment process of patients with MDD, risk and protective factors should be evaluated together, and individualized treatment programs should be targeted. Full article

Background: Peritonsillar abscess (PTA) is a common deep neck infection associated with significant healthcare resource utilization. Needle aspiration (NA) and/or incision & drainage (ID) are the most frequently used treatment modalities; however, their comparative clinical outcomes remain controversial. Methods: This retrospective cohort study included 185 adult patients hospitalized with a diagnosis of PTA between January 2018 and January 2026 at a tertiary care center. Patients aged ≥18 years who underwent NA or ID were included. Demographic characteristics, clinical findings, laboratory parameters at admission, treatment-related variables (type and number of interventions, drainage volume, adjunctive corticosteroid use), microbiological results, and length of hospital stay were recorded. Patients were categorized according to the drainage method performed (NA vs. ID). Results: A total of 185 patients were included, of whom 87 (47%) underwent NA and 98 (53%) underwent ID. There were no significant differences between groups in age, sex, or length of hospital stay (p > 0.05). CRP levels and lymphocyte counts were significantly higher in the NA group (p = 0.028 and p = 0.009, respectively), whereas drainage volume and number of interventions were significantly higher in the ID group (p < 0.001 and p = 0.005, respectively). Successful resolution on the first attempt was more frequent in the ID group (89.8% vs. 75.9%, p = 0.011), while steroid use was more common in the NA group (16.1% vs. 2.0%, p = 0.001). In multivariate analysis, drainage volume, first-attempt success, and corticosteroid use were independently associated with the choice of drainage method (p < 0.05). Conclusions: Both NA and ID are effective treatment options for PTA; however, ID was associated with higher first-attempt success and greater drainage volume. Indeed, NA was more frequently accompanied by steroid therapy. These findings suggest that treatment modality selection may influence short-term clinical outcomes in patients with PTA. Full article

This paper defends the thesis that LLM hallucinations are best explained as a truth representation problem: Current models lack an internal representation of propositions as truth-bearers, so truth and falsity cannot constrain generation in the way factual discourse requires. It begins by surveying leading explanations—computational limits on self-verification, deficiencies in training data as truth sources, and architectural factors—and argues that they converge on the same underlying representational deficit. Next, it reconstructs the philosophical background of current LLM design, showing how optimization for fluent continuation aligns with coherence-style evaluation and with broadly structuralist, relational semantics, before turning to David Chalmers’s recent attempt to secure propositional interpretability by drawing on Davidson/Lewis-style radical interpretation and by locating propositional content in “middle-layer” structures; it argues that this approach downplays the ubiquity of hallucination and inherits instability from post-training edits. Finally, the paper offers a positive proposal: Atomic propositions should be represented in the basic vector layer, reviving a logical atomist program as a principled route to reducing hallucination. Full article

Understanding the long-term impact of historical land system failures on rural elderly dietary habits is essential for enhancing rural well-being. Existing studies focus on physiological effects but often neglect the deep-seated psychological mechanisms and resource boundaries driving irrational late-life consumption. By integrating the Stimulus-Organism-Response (S-O-R) model and compensatory consumption theory, this study uses balanced panel data from the CLHLS and a Cohort-Difference-in-Differences framework to identify causal effects. The results show that: (1) Early-life famine exposure creates a rigid life-cycle consumption imprint. Adolescent exposure leads to significantly higher levels of compensatory food consumption in later life despite current improvements in material conditions. (2) Learned helplessness drives historical trauma into compensation. Mechanism analysis shows that individuals attempt to restore a sense of order and security by controlling micro-level food intake. (3) The behavioral impact of this trauma depends on resource boundary conditions. The compensatory drive is stronger in resource-scarce regions but weakens with individual economic self-reliance. Additionally, professional community counseling shows a reversal effect, surpassing informal family support which suffers from a “compliance paradox”. These results are robust after a series of validation tests. Our study supports shifting rural revitalization policies from material aid to professional psychological intervention. Full article

TFF1 is a secretory polypeptide that is typical of mucous epithelia belonging to the trefoil factor family (TFF) of lectins. Originally, TFF1 was discovered as an estrogen-responsive gene in breast cancer cell lines. However, its major physiological expression site is the stomach where it exists mainly in a monomeric form, with minor amounts of homodimeric as well as heterodimeric forms, such as a high-molecular-mass complex with IgG Fc binding protein (FCGBP). For the first time, we characterized different low-molecular-mass forms of TFF1 in human post-menopausal vaginal specimens, i.e., monomeric and dimeric forms. Attempts to identify high-molecular-mass forms of TFF1, such as TFF1-FCGBP, failed. Based on its known anti-inflammatory effects, TFF1 could play an important role in the homeostasis of vaginal microbiota, which is normally predominated by Lactobacillus spp. Due to its lectin activity, TFF1 might also be capable of binding to members of the vaginal microbiota or to vaginal fungal pathogens. This points to a potential role for TFF1 in the vagina’s innate immune defence and could be of clinical relevance particularly after menopause, e.g., for the treatment of bacterial vaginosis or vulvovaginal candidiasis, as here vaginal dysbiosis is often observed as a consequence of estrogen deficiency. Full article

Mohammed Abed Al-Jabri (d. 2010) is one of the most important and stimulating contemporary Arabic philosophers. He is well-known for his project Critique of Arab Reason (Naqd al-ʿaql al-ʿArabī), in which he deconstructs the Arabic philosophical and cultural tradition, revitalizing the rationalist legacy of the classical period, mainly, the philosophical ideas of Ibn Rushd (Averroes). According to Al-Jabri, the renewal of Arab thought requires a non-traditionalist understanding of tradition. In this paper, I shall critically examine Al-Jabri’s “contextualist” methodology. I first provide some historical background for understanding Al-Jabri’s concern with fostering a critique of Arab reason. Secondly, I discuss the way Al-Jabri reinterprets Islamic intellectual history, emphasizing his attempt to overcome the idiosyncratic approaches to Arab culture, namely, religious Salafists, Orientalists, and left nationalists. Thirdly, I discuss the extent to which his renewal of classical intellectual tradition, mainly his approach to Ibn Rushd, allows for the socio-political and cultural reformation of an Arab identity through his idea of “understanding oneself through the other.” Finally, I highlight some successful aspects of Al-Jabri’s epistemic project and its potential relevance for the present. Full article

Physics-based constitutive modelling remains a cornerstone for predicting ductile damage and fracture in metallic materials, particularly where microstructural mechanisms govern macroscopic response. Over the past two decades, a wide range of crystal plasticity, porous plasticity, and void-based fracture models have been proposed to capture deformation localisation, void growth, and coalescence under complex loading paths. However, these developments are often presented in isolation, obscuring their shared physical assumptions and limiting their transferability across material systems and length scales. This article provides a microstructure-sensitive perspective on the constitutive modelling of ductile damage and fracture, with particular emphasis on crystal plasticity-based frameworks, void growth and coalescence mechanisms, and interface-driven fracture. Rather than attempting an exhaustive review, this review highlights the unifying concepts, modelling trade-offs, and recurring challenges related to parameter identifiability, scale bridging, and predictive robustness. It further clarifies how physics-based constitutive descriptions can be systematically integrated into modern fatigue and fracture assessments and situates these developments relative to emerging data-assisted and machine-learning-enhanced modelling strategies. By reframing established constitutive models within a coherent physical narrative, this perspective aims to support more transparent model selection, improve interpretability, and guide future developments in the multiscale damage and fracture modelling of metallic materials. While these frameworks offer enhanced microstructure sensitivity, their parameter richness and experimental calibration demand currently limit widespread industrial deployment, motivating ongoing work on reduced-order and data-assisted variants. Full article