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15,785 Results Found

  • Article
  • Open Access
19 Citations
7,721 Views
9 Pages

8 September 2017

Barriers to medication adherence stem from multiple factors. An effective and convenient tool is needed to identify these barriers so that clinicians can provide a tailored, patient-centered consultation with patients. The Modified Drug Adherence Wor...

  • Article
  • Open Access
2,500 Views
21 Pages

Adherence is vital for medicine to have an effect, yet adherence is considered to be low, with approximately half of the patients not fully adherent. However, research into adherence tends to focus on quantitative analysis of performance, which fails...

  • Article
  • Open Access
12 Citations
2,103 Views
21 Pages

20 July 2023

The Mediterranean diet (MD) is considered a model for good health, and is promoted worldwide as one of the healthiest dietary patterns. Despite the MD’s health benefits, the literature suggests that adherence to the MD tends to be in decline in...

  • Communication
  • Open Access
3 Citations
2,352 Views
4 Pages

Strategies to Optimize Adherence in Patients with Mycosis Fungoides

  • Warren H. Chan,
  • Daniel J. Lewis,
  • Madeleine Duvic and
  • Steven R. Feldman

30 December 2021

Patient adherence to medications for common skin conditions has been extensively studied over the past two decades, and suboptimal adherence is a primary contributor to treatment failure. The impact of sub-par adherence in cutaneous T-cell lymphoma (...

  • Article
  • Open Access
30 Citations
7,439 Views
10 Pages

The detection and analysis of cases of low medication adherence is important for helping to control tuberculosis (TB). The purpose of this study was to detect low adherence in rural TB patients by using the eight-item Morisky Medication Adherence Sca...

  • Commentary
  • Open Access
5 Citations
3,311 Views
8 Pages

When Multiple Objective Measures of Medication Adherence Indicate Incongruent Adherence Results: An Example with Pediatric Cancer

  • Caitlin J. Cain,
  • Andrea R. Meisman,
  • Kirstin Drucker,
  • Evrosina I. Isaac,
  • Tanvi Verma,
  • Jordyn Griffin and
  • Jennifer M. Rohan

Previous research suggests that children and adolescents with acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) often have difficulty adhering to complex treatment regimens during the maintenance phase of therapy. Measurement of tre...

  • Review
  • Open Access
45 Citations
7,873 Views
9 Pages

Adherence to Therapy in Patients with Multiple Sclerosis—Review

  • Aleksandra Kołtuniuk and
  • Justyna Chojdak-Łukasiewicz

Multiple sclerosis (MS) is a chronic, autoimmune, demyelinating disease of the central nervous system (CNS). MS is an incurable disease. The goal of disease-modifying therapies (DMT) is to slow the progression of the disease, prevent relapses and inc...

  • Review
  • Open Access
1,129 Views
18 Pages

8 December 2025

Tuberculosis is a serious public health issue. It is the most prevalent cause of death from a single infectious agent and globally, it is among the top 10 causes. One of the most crucial strategies to combat the TB pandemic is to administer basic ant...

  • Article
  • Open Access
1 Citations
2,356 Views
10 Pages

3 April 2025

Background/Objectives: This study sought to identify key barriers to treatment adherence in children and adolescents with type 1 diabetes (T1D) using the Adherence Starts with Knowledge-12 (ASK-12) questionnaire and to evaluate its impact on metaboli...

  • Article
  • Open Access
5 Citations
4,163 Views
12 Pages

Medication Adherence and Contraceptive Counseling

  • María Inmaculada de Molina-Fernandez,
  • Laura Reyes-Martí,
  • Miriam De la Flor-López,
  • Maria Jesús Aguarón-García,
  • Alba Roca-Biosca,
  • Lourdes Rubio-Rico,
  • Rosa Dolors Raventós Torner and
  • Francesc Valls-Fonayet

Combined oral contraceptives (COC) are a very popular form of birth control. Incorrect use and lack of adherence to treatment reduce the effectiveness of this method. Having a standard tool to identify poor-adherence profiles quickly and objectively...

  • Article
  • Open Access
14 Citations
5,879 Views
11 Pages

Medication Adherence in Chronic Older Patients: An Italian Observational Study Using Medication Adherence Report Scale (MARS-5I)

  • Gloria Liquori,
  • Aurora De Leo,
  • Emanuele Di Simone,
  • Sara Dionisi,
  • Noemi Giannetta,
  • Elvira Ganci,
  • Sherly Pia Trainito,
  • Giovanni Battista Orsi,
  • Marco Di Muzio and
  • Christian Napoli

Background: the world population is aging, and the prevalence of chronic diseases is increasing. Chronic diseases affect the quality of life of patients and contribute toward increased healthcare costs if patients do not adhere to treatment. This stu...

  • Article
  • Open Access
20 Citations
4,322 Views
10 Pages

Background: Populations living in Mediterranean islands are experiencing a nutrition transition process from traditional to Westernized dietary patterns. No information on this matter regarding individuals living in Malta have been published to date....

  • Article
  • Open Access
1 Citations
1,934 Views
21 Pages

Development and Validation of Predictive Models for Non-Adherence to Antihypertensive Medication

  • Cristian Daniel Marineci,
  • Andrei Valeanu,
  • Cornel Chiriță,
  • Simona Negreș,
  • Claudiu Stoicescu and
  • Valentin Chioncel

21 July 2025

Background and Objectives: Investigating the adherence to antihypertensive medication and identifying patients with low adherence allows targeted interventions to improve therapeutic outcomes. Artificial intelligence (AI) offers advanced tools for an...

  • Article
  • Open Access
10 Citations
7,310 Views
8 Pages

The Effect of Periodization on Training Program Adherence

  • Vicente Javier Clemente-Suárez,
  • Domingo Jesús Ramos-Campo,
  • José Francisco Tornero-Aguilera,
  • Jose A. Parraca and
  • Nuno Batalha

The present research aimed to study the effect of three different training periodization (traditional, reverse, and free training) on the aerobic performance, motivation, and adherence of physically active athletes. We analysed the adherence to three...

  • Article
  • Open Access
2 Citations
1,364 Views
16 Pages

Adherence Barriers, Patient Satisfaction, and Depression in Albanian Ambulatory Patients

  • Sonila Qirko,
  • Vasilika Prifti,
  • Emirjona Kicaj,
  • Rudina Cercizaj and
  • Liliana Rogozea

Background: Medication adherence is essential for managing chronic conditions, while non-adherence remains a widespread issue, leading to poorer health outcomes and higher healthcare costs. This study aimed to identify key adherence barriers, explore...

  • Review
  • Open Access
42 Citations
10,718 Views
11 Pages

It has been shown that the better outcomes of chronic obstructive pulmonary disease (COPD) are closely associated with adherence to drug therapy, independent of the treatment administered. The clinical trial Towards a Revolution in COPD Health (TORCH...

  • Feature Paper
  • Review
  • Open Access
116 Citations
26,117 Views
27 Pages

A Review of Medication Adherence Monitoring Technologies

  • Murtadha Aldeer,
  • Mehdi Javanmard and
  • Richard P. Martin

Medication non-adherence is a prevalent, complex problem. Failure to follow medication schedules may lead to major health complications, including death. Proper medication adherence is thus required in order to gain the greatest possible drug benefit...

  • Article
  • Open Access
27 Citations
4,337 Views
14 Pages

Treatment Adherence in Patients with Obstructive Pulmonary Diseases

  • Henryka Homętowska,
  • Natalia Świątoniowska-Lonc,
  • Jakub Klekowski,
  • Mariusz Chabowski and
  • Beata Jankowska-Polańska

COPD is the third most common cause of death globally. Adherence rates in patients with obstructive pulmonary diseases usually range between 10% and 40%. The aim of the study was to evaluate the level of treatment adherence to inhaled therapy in pati...

  • Article
  • Open Access
2,471 Views
12 Pages

High Implementation Adherence to Lenalidomide in Multiple Myeloma

  • Irina Amitai,
  • Hila Magen,
  • Avi Leader,
  • Antoine Pironet,
  • Eric Tousset,
  • Alon Rozental,
  • Sabina De Geest,
  • Iuliana Vaxman,
  • Pia Raanani and
  • Arnon Nagler

6 November 2025

Background and Purpose: Adherence to oral anticancer therapy correlates with outcome. Lenalidomide (LEN) is an oral mainstay treatment for multiple myeloma (MM), administered in 21-day/7-day (on/off) cycles. Data on LEN adherence is limited. Electron...

  • Article
  • Open Access
7 Citations
3,850 Views
17 Pages

Italian Translation and Validation of the Original ABC Taxonomy for Medication Adherence

  • Sara Mucherino,
  • Marina Maffoni,
  • Clara Cena,
  • Lucrezia Greta Armando,
  • Marta Guastavigna,
  • Valentina Orlando,
  • Giancarlo Orofino,
  • Sara Traina,
  • Anna Giardini and
  • the Collaborative Working Group
  • + 1 author

Medication adherence represents a complex and multifaceted process. Standardized terminology is essential to enable a reproducible process in various languages. The study’s aim was to translate and adapt the original Ascertaining Barriers for C...

  • Review
  • Open Access
8 Citations
8,390 Views
11 Pages

Does Health Literacy Have an Impact on Adherence to Diabetes Mellitus Treatment?

  • Charity Ngoatle,
  • Lina S. Hlahla,
  • Mabitsela H. Mphasha,
  • Tebogo M. Mothiba and
  • Mahlapahlapana J. Themane

2 February 2023

(1) Background: Health literacy is the intersection of general literacy, health, and healthcare, but it can also incorporate elements of other types of literacies to varying degrees. The notion of literacy surfaced from the fear that individuals woul...

  • Review
  • Open Access
65 Citations
12,147 Views
12 Pages

27 January 2015

Poor adherence to treatment is a major factor limiting treatment outcomes in patients with atopic dermatitis. The purpose of our systematic review is to identify techniques that have been tested to increase treatment adherence in atopic dermatitis. A...

  • Article
  • Open Access
45 Citations
7,295 Views
10 Pages

31 July 2020

Adherence to a gluten-free diet (GFD) is currently the mainstay of treatment strategy for celiac disease (CD). The aim of our study was measuring a GFD adherence in CD patients using two newly validated methods of dietary assessment—Standardize...

  • Review
  • Open Access
8 Citations
5,968 Views
11 Pages

Sleep Quality and Medication Adherence in Older Adults: A Systematic Review

  • Leandro Amato,
  • Noemi Giannetta,
  • Sofia Taborri,
  • Sara Dionisi,
  • Nicolò Panattoni,
  • Emanuele Di Simone,
  • Aurora De Leo,
  • Gloria Liquori,
  • Giovanni Battista Orsi and
  • Marco Di Muzio
  • + 1 author

3 September 2024

Sleep quality significantly impacts individuals’ overall health, especially in older adults. Older adults often face comorbid conditions, polypharmacy (the intake of five or more medications per day), and medication non-adherence, which are com...

  • Article
  • Open Access
6 Citations
2,587 Views
11 Pages

Impact of COVID-19 on Adherence to Treatment in Patients with HIV

  • Pablo Carbonero-Lechuga,
  • Javier Castrodeza-Sanz,
  • Iván Sanz-Muñoz,
  • Pilar Marqués-Sánchez,
  • Jose M. Eiros,
  • Carlos Dueñas-Gutiérrez and
  • Camino Prada-García

In patients with human immunodeficiency virus (HIV), adherence to treatment is affected by the adverse effects of treatment, the presence of additional comorbidities, the complexity of dosage, and family and community support. However, one recent cir...

  • Systematic Review
  • Open Access
2 Citations
3,094 Views
24 Pages

Participation and Adherence to Prehabilitation Programs for Colorectal Cancer

  • Misha A. T. Sier,
  • Eva Godina,
  • Omar Mollema,
  • Maud P. P. J. Cox,
  • Thais T. T. Tweed,
  • Jan Willem Greve and
  • Jan H. M. B. Stoot

25 May 2025

Background/Objectives: The preoperative improvement of patients’ functional capacity (prehabilitation) has gained attention in the surgical field, especially for colorectal cancer (CRC) patients. Despite the recognized benefits of prehabilitati...

  • Brief Report
  • Open Access
12 Citations
8,321 Views
8 Pages

The Impact of Non-Adherence to Antihypertensive Drug Therapy

  • Syed Karam Mustafa Gardezi,
  • William W. Aitken and
  • Mohammad Hashim Jilani

18 November 2023

Medication non-adherence is a major healthcare barrier, especially among diseases that are largely asymptomatic, such as hypertension. The impact of poor medication adherence ranges from patient-specific adverse health outcomes to broader strains on...

  • Review
  • Open Access
14 Citations
15,558 Views
19 Pages

26 August 2025

Adherence to medications is a significant challenge in chronic disease management. Poor adherence can lead to adverse patient outcomes including disease progression, increased morbidity, reduced quality of life, higher hospitalization rates, increase...

  • Article
  • Open Access
5 Citations
3,606 Views
13 Pages

Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence

  • Julie L. Barr,
  • Michael Feehan,
  • Casey Tak,
  • Leah A. Owen,
  • Robert C. Finley,
  • Parker A. Cromwell,
  • John H. Lillvis,
  • Patrice M. Hicks,
  • Elizabeth Au and
  • Margaret M. DeAngelis
  • + 7 authors

Glaucoma is the leading cause of irreversible blindness, affecting 76 million globally. It is characterized by irreversible damage to the optic nerve. Pharmacotherapy manages intraocular pressure (IOP) and slows disease progression. However, non-adhe...

  • Feature Paper
  • Review
  • Open Access
53 Citations
8,114 Views
11 Pages

Adherence to Therapy in Glaucoma Treatment—A Review

  • Alexandra-Cătălina Zaharia,
  • Otilia-Maria Dumitrescu,
  • Mădălina Radu and
  • Roxana-Elena Rogoz

22 March 2022

Glaucoma is a chronic disease and the second leading cause of irreversible vision loss worldwide, whose initial treatment consists of self-administered topical ocular hypotensive eyedrops. Adherence with glaucoma medications is a fundamental problem...

  • Article
  • Open Access
1 Citations
1,321 Views
9 Pages

Factors involved in adherence to therapy in fibromyalgia patients

  • Mª Dolores Ruiz-Fernández,
  • Dolores Hernández-Martínez,
  • Antonia Fernández-Leyva and
  • María López-Cano

Fibromyalgia is a chronic disease that it needs of a complex and multiple drug therapy. With the aim to study the degree of adherence to therapy in this disease to the pharmacological treatment prescribed and, to know how they influence a series of v...

  • Article
  • Open Access
26 Citations
6,660 Views
15 Pages

The Role of Stigma Management in HIV Treatment Adherence

  • Lance Rintamaki,
  • Kami Kosenko,
  • Timothy Hogan,
  • Allison M. Scott,
  • Christopher Dobmeier,
  • Erik Tingue and
  • David Peek

Social stigma is linked to improper HIV treatment adherence, but how stigma impairs adherence outcomes is poorly understood. This study included 93 people living with HIV in the United States who participated in focus groups or one-on-one interviews...

  • Systematic Review
  • Open Access
8 Citations
2,697 Views
17 Pages

Risk Factors for Non-Adherence to Medication for Liver Transplant Patients: An Umbrella Review

  • Jordi Colmenero,
  • Mikel Gastaca,
  • Laura Martínez-Alarcón,
  • Cristina Soria,
  • Esther Lázaro and
  • Inmaculada Plasencia

18 April 2024

Background/Objectives: Liver Transplantation (LT) is the second most common solid organ transplantation. Medication adherence on LT patients is key to avoiding graft failure, mortality, and important quality of life losses. The aim of this study is t...

  • Article
  • Open Access
17 Citations
6,069 Views
10 Pages

Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia

  • Eman Alefishat,
  • Anan S. Jarab,
  • Walid Al-Qerem and
  • Lina Abu-Zaytoun

Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in...

  • Review
  • Open Access
16 Citations
9,036 Views
16 Pages

Barriers to Type 1 Diabetes Adherence in Adolescents

  • Sarah Azar,
  • Noa Maroun Abou Jaoude,
  • Andrzej Kędzia and
  • Elżbieta Niechciał

24 September 2024

Background: Adolescence is a particularly crucial period of physical, emotional, and social development and adaptation, rendering these formative years rather challenging for individuals with chronic conditions like type 1 diabetes (T1D). Despite rap...

  • Article
  • Open Access
33 Citations
7,107 Views
9 Pages

Medication Adherence among Patients with Chronic Diseases in Saudi Arabia

  • Khulud Alosaimi,
  • Hassan Alwafi,
  • Yosra Alhindi,
  • Alaa Falemban,
  • Asim Alshanberi,
  • Nahla Ayoub and
  • Safaa Alsanosi

Introduction: The management of chronic illnesses commonly includes a long-term pharmacological approach. Although these medications effectively control disease, their full benefits are often not realized because approximately 50% of patients do not...

  • Article
  • Open Access
42 Citations
9,902 Views
19 Pages

16 November 2015

Breast cancer survivors are at increased risk for breast cancer-related lymphedema (BCRL), a chronic, debilitating, condition that is progressive and requires lifelong self-management. Up to 40% of 3 million breast cancer survivors in the US will de...

  • Review
  • Open Access
41 Citations
11,857 Views
13 Pages

31 August 2022

Pharmaceutical compounding is an important component of pharmacy practice despite its low prevalence. Several therapeutic needs can be met by a compounded medicine such as dosing adjusted for pediatric patients, special drug combinations, medicines f...

  • Article
  • Open Access
1 Citations
1,591 Views
15 Pages

An Entropy-Based Approach to Measuring Diet Adherence

  • Curtis Huffman,
  • Ana G. Ortega-Avila and
  • Héctor Nájera

24 August 2023

The aim of this study is to put forward an approach designed to calculate and sum up discrepancies between the actual food acquisition or intake and any standard or norm. Based on secondary analysis of cross-sectional data from the Mexican National S...

  • Article
  • Open Access
2 Citations
2,321 Views
11 Pages

Adherence and Health Problems in Thai Travellers Living with HIV

  • Krit Madsalae,
  • Thundon Ngamprasertchai,
  • Saranath Lawpoolsri,
  • Rujipas Sirijatuphat,
  • Winai Ratanasuwan,
  • Watcharapong Piyaphanee and
  • Punnee Pitisuttithum

It is important to focus on adherence to antiretroviral therapy (ART) and health problems of travellers living with HIV (TLWHIV) during travel. This study was conducted to investigate factors related to adherence and health problems among TLWHIV. Thi...

  • Article
  • Open Access
25 Citations
7,906 Views
19 Pages

Exploring Rates of Adherence and Barriers to Time-Restricted Eating

  • Paul W. Jefcoate,
  • M. Denise Robertson,
  • Jane Ogden and
  • Jonathan D. Johnston

16 May 2023

Whilst the treatment and prevention of overweight and obesity-related disease is managed by restricting daily energy intake, long-term adherence to dietary strategies appears unsustainable. Time-restricted eating (TRE) aims to position energy intake...

  • Article
  • Open Access
4 Citations
2,409 Views
13 Pages

Longitudinal Trajectory Modeling to Assess Adherence to Sacubitril/Valsartan among Patients with Heart Failure

  • Sara Mucherino,
  • Alexandra Lelia Dima,
  • Enrico Coscioni,
  • Maria Giovanna Vassallo,
  • Valentina Orlando and
  • Enrica Menditto

Medication adherence in chronic conditions is a long-term process. Modeling longitudinal trajectories using routinely collected prescription data is a promising method for describing adherence patterns and identifying at-risk groups. The study aimed...

  • Article
  • Open Access
9 Citations
4,257 Views
19 Pages

Medication Adherence in a Community Population with Uncontrolled Asthma

  • Sarah Serhal,
  • Bandana Saini,
  • Sinthia Bosnic-Anticevich,
  • Ines Krass,
  • Frances Wilson and
  • Carol Armour

7 October 2020

It is well documented that the use of medications in asthma and allergic rhinitis is often suboptimal, and consequently, patients remain symptomatic. This study aimed to determine the extent and type of medication-related issues contributing to poor...

  • Article
  • Open Access
11 Citations
3,893 Views
10 Pages

Adherence to Anti-Viral Treatment for Chronic Hepatitis B

  • Naim Abu-Freha,
  • Muhammad Abu Tailakh,
  • Alexander Fich,
  • Nasreen Abu Bader,
  • Yonat Shemer-Avni,
  • Farhan Alsana,
  • Nava Gasper,
  • Heba Abu-Kaf and
  • Ohad Etzion

19 June 2020

Adherence to treatment of chronic Hepatitis B Virus (HBV) is an important issue and can affect the complication rate. Nucleos(t)ide analogue as oral treatments are used for patients with necro-inflammatory activity and high viral load, with the goal...

  • Article
  • Open Access
3,177 Views
11 Pages

The Impact of Home Medication Management Practices on Medication Adherence

  • Lisa Gualtieri,
  • Meredith Steinfeldt,
  • Eden Shaveet,
  • Brandon Estime and
  • Meera Singhal

11 September 2024

Medication adherence is a vexing challenge, with over 50% of US adults not adhering to their prescribed medication regimen. Most medications are self-administered by patients at home, requiring them to independently develop and manage their own medic...

  • Article
  • Open Access
10 Citations
1,333 Views
9 Pages

Adherence to Treatment in Asthma and COPD Patients in Their Doctors’ Assessment

  • Przemysław Kardas,
  • Paweł Lewek and
  • Marcin Strzondała

10 November 2015

Introduction: Adherence to therapy is one of the basic preconditions of successful treatment of asthma and COPD. Unfortunately, many patients take their medication incorrectly. The aim of this study was to assess doctors’ knowledge of this phenomenon...

  • Article
  • Open Access
46 Citations
11,528 Views
12 Pages

Knowledge about Disease, Medication Therapy, and Related Medication Adherence Levels among Patients with Hypertension

  • Anna Gavrilova,
  • Dace Bandere,
  • Ieva Rutkovska,
  • Dins Šmits,
  • Baiba Mauriņa,
  • Elita Poplavska and
  • Inga Urtāne

28 October 2019

Background and Objectives: A particular problem in cardiology is poor adherence to pharmacological treatment among patients with hypertension. It is known that approximately half of these patients do not use their medications as prescribed by their d...

  • Article
  • Open Access
6 Citations
2,646 Views
9 Pages

26 October 2023

Poor adherence to a gluten-free diet for those with celiac disease is a well-established risk factor, leading to gastrointestinal symptoms, malabsorption of nutrients, and psychiatric complications. Previous studies have shown that those outside urba...

  • Article
  • Open Access
20 Citations
1,054 Views
7 Pages

Patient Adherence to Aromatase Inhibitor Treatment in the Adjuvant Setting

  • S. Verma,
  • Y. Madarnas,
  • S. Sehdev,
  • G. Martin and
  • J. Bajcar

Improvements in adjuvant systemic therapy and detection of early disease have resulted in a decline of breast cancer death rates across all patient age groups in Canada. Non-adherence to adjuvant hormonal therapy in the setting of early breast cancer...

  • Article
  • Open Access
6 Citations
6,003 Views
14 Pages

Impact of Diabetes Perceptions on Medication Adherence in Japan

  • Koki Urata,
  • Kana Hashimoto,
  • Reiko Horiuchi,
  • Kiichi Fukui and
  • Kunizo Arai

29 October 2019

Background: Patients’ perception of diabetes mellitus is one of the psychosocial factors influencing diabetic behavior. This patients’ perception of the disease is a mental image formed from the experience of patients with type 2 diabetes...

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