Search Results (423)

This study explores the application of multiple predictive algorithms under general versus route-specialized modeling strategies to estimate passenger boarding demand in public bus transportation systems. Accurate estimation of boarding patterns is essential for optimizing service planning, improving passenger comfort, and enhancing operational efficiency. This research evaluates a range of predictive models to identify the most effective techniques for forecasting demand across different routes and times. Two modeling strategies were implemented: a generalistic approach and a specialized one. The latter was designed to capture route-specific characteristics and variability. A real-world case study from a medium-sized metropolitan region in Brazil was used to assess model performance. Results indicate that ensemble-tree-based models, particularly XGBoost, achieved the highest accuracy and robustness in handling nonlinear relationships and complex interactions within the data. Compared to the generalistic approach, the specialized approach demonstrated superior adaptability and precision, making it especially suitable for long-term and strategic planning applications. It reduced the average RMSE by 19.46% (from 13.84 to 11.15) and the MAE by 17.36% (from 9.60 to 7.93), while increasing the average R² from 0.289 to 0.344. However, these gains came with higher computational demands and mean Forecast Bias (from 0.002 to 0.560), indicating a need for bias correction before operational deployment. The findings highlight the practical value of predictive modeling for transit authorities, enabling data-driven decision making in fleet allocation, route planning, and service frequency adjustment. Moreover, accurate demand forecasting contributes to cost reduction, improved passenger satisfaction, and environmental sustainability through optimized operations. Full article

This paper proposes an efficient and automated smart healthcare communication framework that integrates a two-level filtering scheme with a multi-objective Genetic Algorithm (GA) to enhance the reliability, timeliness, and energy efficiency of Internet of Medical Things (IoMT) systems. In the first stage, physiological signals collected from heterogeneous sensors (e.g., blood pressure, glucose level, ECG, patient movement, and ambient temperature) were pre-processed using an adaptive least-mean-square (LMS) filter to suppress noise and motion artifacts, thereby improving signal quality prior to analysis. In the second stage, a GA-based optimization engine selects optimal routing paths and transmission parameters by jointly considering end-to-end delay, Signal-to-Noise Ratio (SNR), energy consumption, and packet loss ratio (PLR). The two-level filtering strategy, i.e., LMS, ensures that only denoised and high-priority records are forwarded for more processing, enabling timely delivery for supporting the downstream clinical network by optimizing the communication. The proposed mechanism is evaluated via extensive simulations involving 30–100 devices and multiple generations and is benchmarked against two existing smart healthcare schemes. The results demonstrate that the integrated GA and filtering approach significantly reduces end-to-end delay by 10%, as well as communication latency and energy consumption, while improving the packet delivery ratio by approximately 15%, as well as throughput, SNR, and overall Quality of Service (QoS) by up to 98%. These findings indicate that the proposed framework provides a scalable and intelligent communication backbone for early disease detection, continuous monitoring, and timely intervention in smart healthcare environments. Full article

In the face of accelerating climate change and urbanization, sustainable mobility infrastructure plays a critical role in reducing greenhouse gas emissions. This article assesses the Sunglider concept—an elevated, solar-powered transport system—through the New European Bauhaus (NEB) Compass, which emphasizes sustainability, inclusion, and esthetic value. Designed by architect Peter Kuczia and collaborators, Sunglider combines photovoltaic energy generation with modular, parametrically designed wooden pylons to form a lightweight, climate-positive mobility solution. The study evaluates the system’s technological feasibility, environmental performance, and urban integration potential, drawing on existing design documentation and simulation-based estimates. While Sunglider demonstrates strong alignment with NEB principles, including zero-emission operation and material circularity, its implementation is challenged by high initial investment, political and planning complexities, and integration into dense urban environments. Mitigation strategies—such as adaptive routing, visual screening, and universal station access—are proposed to address concerns around privacy, esthetics, and accessibility. The article positions Sunglider as a scalable and replicable model for mid-sized European cities, capable of advancing inclusive, carbon-neutral mobility while enhancing the urban experience. It concludes with policy and research recommendations, highlighting the importance of embedding infrastructure innovation within broader ecological and cultural transitions. Full article

Deep reinforcement learning (DRL) with self-play has emerged as a promising paradigm for solving combinatorial optimization (CO) problems. The recently proposed Gumbel AlphaZero Plan-to-Play (GAZ PTP) framework adopts a competitive training setup between a learning agent and an opponent to tackle classical CO tasks such as the Traveling Salesman Problem (TSP). However, in complex and multi-constrained environments like the Electric Vehicle Routing Problem (EVRP), standard self-play often suffers from opponent mismatch: when the opponent is either too weak or too strong, the resulting learning signal becomes ineffective. To address this challenge, we introduce Two-Stage Self-Play GAZ PTP (TSS GAZ PTP), a novel DRL method designed to maintain adaptive and effective learning pressure throughout the training process. In the first stage, the learning agent, guided by Gumbel Monte Carlo Tree Search (MCTS), competes against a greedy opponent that follows the best historical policy. As training progresses, the framework transitions to a second stage in which both agents employ Gumbel MCTS, thereby establishing a dynamically balanced competitive environment that encourages continuous strategy refinement. The primary objective of this work is to develop a robust self-play mechanism capable of handling the high-dimensional constraints inherent in real-world routing problems. We first validate our approach on the TSP, a benchmark used in the original GAZ PTP study, and then extend it to the multi-constrained EVRP, which incorporates practical limitations including battery capacity, time windows, vehicle load limits, and charging infrastructure availability. The experimental results show that TSS GAZ PTP consistently outperforms existing DRL methods, with particularly notable improvements on large-scale instances. Full article

Balancing convergence accuracy and population diversity remains a fundamental challenge in multi-objective optimization, particularly for complex and constrained engineering problems. To address this issue, this paper proposes a novel Multi-Objective Crested Porcupine Optimizer (MOCPO), inspired by the hierarchical defensive behaviors of crested porcupines. The proposed algorithm integrates four biologically motivated defense strategies—vision, hearing, scent diffusion, and physical attack—into a unified optimization framework, where global exploration and local exploitation are dynamically coordinated. To effectively extend the original optimizer to multi-objective scenarios, MOCPO incorporates a reference-point guided external archiving mechanism to preserve a well-distributed set of non-dominated solutions, along with an environmental selection strategy that adaptively partitions the objective space and enhances solution quality. Furthermore, a multi-level leadership mechanism based on Euclidean distance is introduced to provide region-specific guidance, enabling precise and uniform coverage of the Pareto front. The performance of MOCPO is comprehensively evaluated on 18 benchmark problems from the WFG and CF test suites. Experimental results demonstrate that MOCPO consistently outperforms several state-of-the-art multi-objective algorithms, including MOPSO and NSGA-III, in terms of IGD, GD, HV, and Spread metrics, achieving the best overall ranking in Friedman statistical tests. Notably, the proposed algorithm exhibits strong robustness on discontinuous, multimodal, and constrained Pareto fronts. In addition, MOCPO is applied to UAV path planning in four complex terrain scenarios constructed from real digital elevation data. The results show that MOCPO generates shorter, smoother, and more stable flight paths while effectively balancing route length, threat avoidance, flight altitude, and trajectory smoothness. These findings confirm the effectiveness, robustness, and practical applicability of MOCPO for solving complex real-world multi-objective optimization problems. Full article

To efficiently reuse endless fibre-reinforced composites after their life cycle, the recovery of endless fibres including matrix material with subsequent reprocessing in their original state is desirable. Thanks to their covalent adaptive networks, vitrimers offer ideal properties for enabling new repair and circular strategies for composites. In order to evaluate the detachability—meaning the separation of single laminate layers—and recycling potential for continuous fibre reinforcement, process routes and quality parameters must be established. In this study, the double cantilever beam test is used to test the adhesion based on the detachment of continuous fibre layers, and the interlaminare fracture toughness of mode I (G_IC) is measured as a parameter for the required energy for detachment. It was shown that G_IC increases above the vitrimer transition temperature and is higher than for reference specimens with an epoxy matrix. Surface roughness is measured to determine the mechanical and thermal degradation of the chemical network structure and additionally shows fibre cracking and defects in fibre–matrix interfaces. This allows the recycling process to be evaluated up to the production of a second generation, with the aim of identifying the recycling potential of the vitrimer matrix and implementing it for industrial processes. An efficient recycling strategy of the continuous fibre-reinforced vitrimers was thus demonstrated by hot pressing at 190 °C for 45 min, giving vitrimer samples a second life. Full article

To address the issues of parameter coupling and high computational demands in existing feed-forward Gaussian splatting methods, we propose Gaussian Patch-level Mixture-of-Experts Splatting (GaPMeS), a lightweight feed-forward 3D Gaussian reconstruction model based on a mixture-of-experts (MoE) multi-task decoupling framework. GaPMeS employs a dual-routing gating mechanism to replace heavy refinement networks, enabling task-adaptive feature selection at the image patch level and alleviating the gradient conflicts commonly observed in shared-backbone architectures. By decoupling Gaussian parameter prediction into four independent sub-tasks and incorporating a hybrid soft–hard expert selection strategy, the model maintains high efficiency with only 14.6 M parameters while achieving competitive performance across multiple datasets—including a Structural Similarity Index (SSIM) of 0.709 on RealEstate10K, a Peak Signal-to-Noise Ratio (PSNR) of 19.57 on DL3DV, and a 26.0% SSIM improvement on real industrial scenes. These results demonstrate the model’s superior efficiency and reconstruction quality, offering a new and effective solution for high-quality sparse-view 3D reconstruction. Full article

Wireless Sensor Networks (WSNs) are pivotal for data acquisition, yet reliability is severely constrained by routing voids induced by sparsity, uneven energy, and high dynamicity. To address these challenges, the Hybrid Acoustic-Optical Adaptive Void-handling Protocol (HAO-AVP) is proposed to satisfy the requirements for highly reliable communication in complex underwater environments. First, targeting uneven energy, a reinforcement learning mechanism utilizing Gini coefficient and entropy is adopted. By optimizing energy distribution, voids are proactively avoided. Second, to address routing interruptions caused by the high dynamicity of topology, a collaborative mechanism for active prediction and real-time identification is constructed. Specifically, this mechanism integrates a Markov chain energy prediction model with on-demand hop discovery technology. Through this integration, precise anticipation and rapid localization of potential void risks are achieved. Finally, to recover damaged links at the minimum cost, a four-level progressive recovery strategy, comprising intra-medium adjustment, cross-medium hopping, path backtracking, and Autonomous Underwater Vehicle (AUV)-assisted recovery, is designed. This strategy is capable of adaptively selecting recovery measures based on the severity of the void. Simulation results demonstrate that, compared with existing mainstream protocols, the void identification rate of the proposed protocol is improved by approximately 7.6%, 8.4%, 13.8%, 19.5%, and 25.3%, respectively, and the void recovery rate is increased by approximately 4.3%, 9.6%, 12.0%, 18.4%, and 24.2%, respectively. In particular, enhanced robustness and a prolonged network life cycle are exhibited in sparse and dynamic networks. Full article

Background/Objectives: Glioblastoma (GBM) remains the most aggressive primary brain tumor in adults, with limited therapeutic options and poor prognosis despite maximal surgery, radiotherapy, and chemotherapy. The complex and immunosuppressive tumor microenvironment, pronounced intratumoral heterogeneity, and the presence of the blood–brain barrier (BBB) severely restrict the efficacy of conventional and emerging therapies. In this context, cell-based strategies leveraging macrophages, mesenchymal stromal cells (MSCs), and their derivatives have gained attention as “cellular allies” capable of modulating the GBM microenvironment and acting as targeted delivery platforms. Methods: This review systematically analyzes preclinical and early clinical literature on macrophage- and MSC-based therapeutic strategies in GBM, including engineered cells, extracellular vesicles (EVs), membrane-coated nanoparticles, and hybrid biomimetic systems. Studies were selected based on relevance to GBM biology, delivery across or bypass of the BBB, microenvironmental modulation, and translational potential. Evidence from in vitro models, orthotopic and syngeneic in vivo models, and available clinical trials was critically evaluated, with emphasis on efficacy endpoints, biodistribution, safety, and manufacturing considerations. Results: The reviewed evidence demonstrates that macrophages and MSCs can function as active therapeutic agents or delivery vehicles, enabling localized oncolysis, immune reprogramming, stromal and vascular remodeling, and enhanced delivery of viral, genetic, and nanotherapeutic payloads. EVs and membrane-based biomimetic platforms further extend these capabilities while reducing cellular risks. However, therapeutic efficacy is highly context-dependent, influenced by tumor heterogeneity, BBB integrity, delivery route, and microenvironmental dynamics. Clinical translation remains limited, with most approaches at preclinical or early-phase clinical stages. Conclusions: Cell-based and cell-derived platforms represent a promising but still evolving therapeutic paradigm for GBM. Their successful translation will require rigorous biomarker-driven patient selection, improved models that capture invasive GBM biology, scalable GMP-compliant manufacturing, and rational combination strategies to overcome adaptive resistance mechanisms. Full article

Klebsiella oxytoca has emerged as an important opportunistic pathogen in nosocomial infections, particularly during the COVID-19 pandemic, due to its capacity to acquire and disseminate resistance and virulence genes through horizontal gene transfer (HGT). This study presents a genome-based comparative analysis of K. oxytoca within the genus Klebsiella, aimed at exploring the evolutionary plausibility of outer membrane vesicle (OMV) associated processes in bacterial adaptation. Using publicly available reference genomes, we analyzed pangenome structure, phylogenetic relationships, and the distribution of mobile genetic elements, resistance determinants, virulence factors, and genes related to OMV biogenesis. Our results reveal a conserved set of envelope associated and stress responsive genes involved in vesiculogenic pathways, together with an extensive mobilome and resistome characteristic of the genus. Although these genomic features are consistent with conditions that may favor OMV production, they do not constitute direct evidence of functional OMV mediated horizontal gene transfer. Instead, our findings support a hypothesis generating evolutionary framework in which OMVs may act as a complementary mechanism to established gene transfer routes, including conjugation, integrative mobile elements, and bacteriophages. Overall, this study provides a genomic framework for future experimental and metagenomic investigations into the role of OMV-associated processes in antimicrobial resistance dissemination and should be interpreted as a recently identified evolutionary strategy inferred from genomic data, rather than a novel or experimentally validated mechanism. Full article

Simultaneous optimization of vehicle routing and cargo loading is essential for reducing operational costs and improving the environmental performance of logistics systems. To overcome the limitations of traditional sequential approaches to the one-to-many pickup and delivery vehicle routing problem with three-dimensional loading constraints (3L-PDVRP), this paper proposes a deeply coupled hybrid genetic algorithm (HGA). The algorithm adopts a grouping-based genetic encoding strategy to accommodate variable fleet sizes and incorporates a tree-search-based loading module. A dynamic three-dimensional loading feasibility verification mechanism is embedded directly into the evolutionary search so that routing decisions are continuously guided by fragility, stacking stability, support constraints, and other loading constraints. In addition, an adaptive hybrid insertion strategy is employed to balance global exploration and local exploitation during route construction and repair. Extensive computational experiments on extended benchmark instances derived from standard datasets show that the proposed method consistently outperforms a large neighborhood search (LNS)-based baseline from the literature, reducing the average total travel distance by 10.60% and increasing the average vehicle loading rate by 2.76%. These results indicate that the proposed HGA provides an effective approach to the synergistic optimization of routing and loading in one-to-many distribution settings, offering practical value for lowering transportation costs and supporting more sustainable logistics operations. This methodology provides decision support for logistics enterprises, reducing travel distances while ensuring three-dimensional loading feasibility, thereby enabling greener and safer transportation operations. Full article

Wireless sensor networks (WSNs) contend with the critical challenge of balancing energy conservation against data transmission delay, a trade-off that protocols such as PEGASIS—while being strong in energy efficiency—fail to manage optimally due to resulting high latency, unbalanced load distribution, and suboptimal cluster formation. To address these limitations, this paper introduces the Enhanced Multi-Objective PEGASIS (EMO-PEGASIS) protocol, which is designed and implemented using a dual-phase machine learning strategy. This multi-objective approach works in two stages. First, it utilises K-means clustering to achieve robust spatial partitioning of the network. Second, it employs K-Nearest Neighbours (K-NN) classification to enable adaptive and intelligent routing. The simulation was performed using MATLAB R2025a, and the results show that EMO-PEGASIS addresses this multi-objective optimisation problem. The proposed EMO-PEGASIS protocol achieves a 45% reduction in average energy consumption, a 38% decrease in end-to-end delay, and a 67% increase in network lifetime compared to the original PEGASIS protocol. Additionally, EMO-PEGASIS demonstrates enhanced stability and effective load balancing under heterogeneous network configurations, while maintaining an excellent packet delivery ratio of 96.8%. These findings underscore the effectiveness of integrating machine learning techniques, which ultimately yield enhanced performance and enable reliable multi-objective optimisation within energy- and delay-constrained WSN environments. Full article

The Wua-Lai silvercraft community in Chiang Mai is experiencing a widening disconnect with younger visitors, raising concerns about the erosion of intangible cultural heritage. This study evaluates “Silver Craft Journey,” a location-based augmented reality (LBAR) system designed to revitalize cultural engagement and enhance cultural-heritage experience through context-aware, gamified exploration. A quasi-experimental field study with 254 participants across three age groups examined the system’s impact on cultural-heritage experience, knowledge acquisition, and real-world engagement. Results demonstrate substantial knowledge gains, with a mean increase of 7.74 points (SD = 4.37) and a large effect size (Cohen’s d = 1.77), supporting the effectiveness of LBAR in supporting tangible and intangible heritage understanding. Behavioral log data reveal clear age-related engagement patterns: older participants (41–51) showed declining mission completion rates and reduced interaction times at later points of interest, which may reflect increased cognitive and physical demands during extended AR navigation under real-world conditions. These findings underscore the potential of location-based AR to enhance cultural-heritage experience in real-world settings while highlighting the importance of age-adaptive interaction and route-design strategies. The study contributes a replicable model for integrating digital tourism, embodied AR experience, and community-based heritage preservation. Full article

In struggling against invasive species ravaging riverscape ecosystems, gaps in dispersal pathway knowledge and fragmented approaches across scales have long stalled effective riparian management worldwide. To reduce these limitations and enhance invasion management strategies, selecting appropriate alien species as models for in-depth pathway analysis is essential. Alternanthera philoxeroides (Mart.) Griseb. (alligator weed) emerges as an exemplary model species, boasting an invasion record of around 120 years spanning five continents worldwide, supported by genetic evidence of repeated introductions. In addition, the clonal reproduction of A. philoxeroides supports swift establishment, while its amphibious versatility allows occupation of varied riparian environments, with spread driven by natural water-mediated dispersal (hydrochory) and human-related vectors at multiple scales. Thus, leveraging A. philoxeroides, this review proposes a comprehensive multi-scale framework, which integrates monitoring with remote sensing, environmental DNA, Internet of Things, and crowdsourcing for real-time detection. Also, the framework can further integrate, e.g., MaxEnt (Maximum Entropy Model) for climatic suitability and mechanistic simulations of hydrodynamics and human-mediated dispersal to forecast invasion risks. Furthermore, decision-support systems developed from the framework can optimize controls like herbicides and biocontrol, managing uncertainties adaptively. At the global scale, the dispersal paradigm can employ AI-driven knowledge graphs for genetic attribution, multilayer networks, and causal inference to trace pathways and identify disruptions. Based on the premise that our multi-scale framework can bridge invasion ecology with riverscape management using A. philoxeroides as a model, we contend that the implementation of the proposed framework tackles core challenges, such as sampling biases, shifting environmental dynamics, eco–evolutionary interactions using stratified sampling, and adaptive online algorithms. This methodology is purposed to offer scalable tools for other aquatic invasives, evolving management from reactive measures to proactive, network-based approaches that effectively interrupt dispersal routes. Full article

In automated warehousing scenarios, mobile UHF RFID robots typically operate along preset fixed paths to collect basic information from goods tags. They lack the ability to perceive shelf layouts and goods distribution, leading to problems such as missing reads and low inventory efficiency. To address this issue, this paper proposes a cross-layer sensing method for mobile UHF RFID robot reading states based on multiple linear regression-orthogonal least squares (MLR-OLS) and random forest. For shelf state sensing, a position sensing model is constructed based on the physical layer, and MLR-OLS is used to estimate shelf positions and interaction time. For good state sensing, combining physical layer and MAC layer features, a K-means-based tag density classification method and a missing tag count estimation algorithm based on frame states and random forest are proposed to realize the estimation of goods distribution and the number of missing goods. On this basis, according to the read state sensing results, this paper further proposes an adaptive reading strategy for RFID robots to perform targeted reading on missing goods. Experimental results show that when the robot is moving at medium and low speeds, the proposed method can achieve centimeter-level shelf positioning accuracy and exhibit high reliability in goods distribution sensing and missing goods count estimation, and the adaptive reading strategy can significantly improve the goods read rate. This paper realizes cross-layer sensing and read optimization of the RFID robot system, providing a theoretical basis and technical route for the application of mobile UHF RFID robot systems. Full article