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Search Results (6,416)

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92 pages, 20403 KB  
Article
Hypersonic Leading-Edge Cooling—A Comprehensive Review
by Mohammed Aleemuddin, Md Amzad Hossain and Adittya Barua
Aerospace 2026, 13(7), 573; https://doi.org/10.3390/aerospace13070573 (registering DOI) - 25 Jun 2026
Abstract
Human innovation has continually expanded the boundaries of knowledge, from mastering atomic science to reaching the Moon and now into the era of Industry 4.0, where artificial intelligence, the Internet, and advanced additive manufacturing turn imagination into reality. Among these achievements, hypersonic vehicles [...] Read more.
Human innovation has continually expanded the boundaries of knowledge, from mastering atomic science to reaching the Moon and now into the era of Industry 4.0, where artificial intelligence, the Internet, and advanced additive manufacturing turn imagination into reality. Among these achievements, hypersonic vehicles represent a pinnacle of technological advancement. Modern vehicles reach speeds exceeding Mach 27 (approximately 9300 m/s), where the air at the leading edges transforms into a chemically reactive, thermally ionized plasma. At such velocities, stagnation temperatures climb to 9000–12,000 K (8726.85–11,726.85 °C), creating one of the most extreme environments encountered by any human-made system—conditions under which conventional materials cannot survive without advanced cooling strategies. To address this challenge, researchers worldwide have developed and experimentally validated a range of thermal protection and leading-edge cooling techniques. This review presents the historical evolution of hypersonic vehicles, highlights recent advancements, examines the key challenges posed by sustained hypersonic flight, and surveys state-of-the-art cooling strategies. The discussion emphasizes methods that combine passive, active, adaptive, and hybrid approaches to protect vehicle integrity under extreme thermal loads, providing insight into the current and future capabilities of hypersonic thermal manageme nt. Full article
(This article belongs to the Special Issue High Speed Aircraft and Engine Design)
20 pages, 1981 KB  
Article
Development and Performance Evaluation of a High-Temperature-Resistant Salt-Responsive Micro-Crosslinked Polymer Gel Filtration Loss Reducer
by Fengfeng Xiao, Yuhao Xia, Wushuo Liu, Jingping Liu and Yuanwei Sun
Gels 2026, 12(7), 564; https://doi.org/10.3390/gels12070564 (registering DOI) - 25 Jun 2026
Abstract
To address the difficulty in controlling the filtration performance of water-based drilling fluids under high-temperature and high-salinity conditions during the drilling of deep and ultra-deep wells, a salt-responsive micro-crosslinked polymer gel filtration loss reducer, designated LZX, was developed. The synthesis employed 2-acrylamido-2-methylpropane sulfonic [...] Read more.
To address the difficulty in controlling the filtration performance of water-based drilling fluids under high-temperature and high-salinity conditions during the drilling of deep and ultra-deep wells, a salt-responsive micro-crosslinked polymer gel filtration loss reducer, designated LZX, was developed. The synthesis employed 2-acrylamido-2-methylpropane sulfonic acid (AMPS), N,N-dimethylacrylamide (DMAA), dimethyldiallylammonium chloride (DMDAAC), and a betaine monomer containing an unsaturated double bond as monomers, with polyethylene glycol diacrylate (PEGDA) introduced as a crosslinker. Experimental results showed that the product structure matched the design expectations, and the thermal decomposition temperature of the main molecular chain exceeded 290 °C, indicating good thermal stability. At 220 °C under saturated salt conditions, a dosage of 2.5 wt% LZX maintained the API filtration loss at 5.8 mL and the HPHT filtration loss at 28.6 mL. Comparative experiments at different temperatures demonstrated that LZX exhibited superior filtration control performance compared to the commercial high-temperature filtration reducer Driscal Temp and Driscal D. The micro-crosslinked structure of LZX enhanced the rigidity of the molecular chains, raising the upper limit of its thermal resistance. Rheological and viscosity-average molecular weight measurements revealed that LZX exhibited typical antipolyelectrolyte behavior in high-salinity environments—the molecular chains tended to extend and the filtration reduction capability was accordingly maintained—preliminarily achieving a functional transition from passive salt tolerance to active salt responsiveness. LZX is expected to support the construction of high-performance water-based drilling fluids with high temperature and high salt resistance for future deep-earth drilling. Full article
(This article belongs to the Topic Polymer Gels for Oil Drilling and Enhanced Recovery)
38 pages, 3338 KB  
Article
From Vulnerability to Resilience: Passive Design Strategies for Optimizing Building Envelope Heat Exchange to Reduce Cooling Loads in a Warming World
by Tao Ning, Junxue Zhang, Hairuo Wang and Ge Song
Buildings 2026, 16(13), 2513; https://doi.org/10.3390/buildings16132513 (registering DOI) - 24 Jun 2026
Abstract
Traditional air conditioning consumes substantial electricity, exacerbates the urban heat island effect, and creates a maladaptive feedback loop, necessitating a shift toward passive-first net-zero pathways. This study takes a typical six-story residential building in Nanjing’s hot summer and cold winter climate zone as [...] Read more.
Traditional air conditioning consumes substantial electricity, exacerbates the urban heat island effect, and creates a maladaptive feedback loop, necessitating a shift toward passive-first net-zero pathways. This study takes a typical six-story residential building in Nanjing’s hot summer and cold winter climate zone as a case study. Using EnergyPlus hourly simulations, three progressive passive strategy packages are designed to quantify the impact of building envelope heat exchange on cooling loads, grid stress, and heat resilience. Package A includes external shading and natural ventilation. Package B adds reflective coating and a green roof. Package C further adds night ventilation precooling and high-performance windows. The results show that Package C achieves a 62.5% reduction in peak cooling load and a 63.0% reduction in seasonal cooling load. Daytime peak inward heat gain decreases from 68 W/m2 to 22 W/m2, while nighttime outward heat dissipation increases from 12 W/m2 to 38 W/m2. Under an extreme heat day of 41.2 °C with no active cooling, indoor peak temperature drops from 36.8 °C to 29.4 °C, and heat risk hours decrease by 73.6%. Peak-hour power demand is reduced by 70.4%, with a systemic leverage factor of 1.08. Innovations include achieving over 60% load reduction using only mature passive strategies, introducing the systemic leverage factor to quantify urban heat island mitigation benefits, and establishing a vulnerability-to-resilience transformation framework. The passive-first pathway validates building envelope as the first line of defense for net-zero futures. However, the findings are based on a typical six-story residential building in Nanjing and require validation through field measurements or broader application across different climate zones and building typologies before generalization. Full article
22 pages, 3635 KB  
Article
Assessment of Treatment Technologies and Research on Governance Models for Acid Mine Drainage from Closed Coal Mines in Karst Regions
by Chong Li, Yanan Jiao, Xiaoying Zhao, Bin Yang and Bo Bai
Water 2026, 18(13), 1546; https://doi.org/10.3390/w18131546 (registering DOI) - 24 Jun 2026
Abstract
Acid mine drainage (AMD) pollution from closed coal mines in karst regions represents a major environmental challenge in the global mining industry. The complexity of hydrogeological conditions in such regions leads to significant challenges in both predictability and controllability of pollution. Taking the [...] Read more.
Acid mine drainage (AMD) pollution from closed coal mines in karst regions represents a major environmental challenge in the global mining industry. The complexity of hydrogeological conditions in such regions leads to significant challenges in both predictability and controllability of pollution. Taking the Yudong River Basin in Guizhou Province, Southwest China, as the study area, and based on six years (2017–2023) of systematic remediation practices and monitoring data, this study systematically evaluates the effectiveness and applicable conditions of three types of treatment technologies: centralized treatment stations, source control combined with end-of-pipe treatment, and water-sealing ecological plugging. On this basis, governance models applicable to karst regions are distilled. The results show that after six years of remediation, the number of pollution points in the Yudong River Basin decreased from 27 to 12. At the outflow section, the total Fe reduction rate reached 88.3%, the total Mn reduction rate reached 62.3%, and the proportion of contaminated river length was reduced by 78.5%. Each of the three technologies has its own applicable conditions. Centralized treatment stations, characterized by mature technology but high operational costs, are suitable for emergency transition periods. Source control combined with end-of-pipe treatment addresses both symptoms and root causes, making it applicable to complex pollution points. Water-sealing ecological plugging, although cost-controllable, carries a risk of secondary pollution in karst-developed areas. The failure of water-sealing ecological plugging technology is mainly attributed to two mechanisms: bypass flow through karst conduits and overflow induced by water level rise. Based on the six-year remediation practice, this study proposes a source control model for karst conduits centered on the core concepts of “filling, isolating, plugging, intercepting, draining, and controlling”. The implementation process consists of four stages: detailed investigation, graded optimization, stepwise implementation, and long-term monitoring. The core innovation lies in the cross-disciplinary application of coal mine water control techniques to environmental remediation, achieving a shift from passive end-of-pipe treatment to active source control. This model can provide theoretical reference and practical guidance for karst mining areas in Southwest China and other regions with similar geological conditions. Full article
(This article belongs to the Section Water Quality and Contamination)
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21 pages, 2514 KB  
Article
Identification and Characterization of Creep-Capable Faults Using Advanced HVSR Processing: Implications for Seismic Microzonation (Etna, Italy)
by Sabrina Grassi, Claudia Pirrotta, Sebastiano Imposa, Gabriele Quattrocchi and Gabriele Morreale
Geosciences 2026, 16(7), 248; https://doi.org/10.3390/geosciences16070248 (registering DOI) - 24 Jun 2026
Abstract
The southeastern flank of Mt. Etna is affected by the presence of active faults capable of adapting to deformation through both seismic slip and aseismic creep, posing challenges for seismic microzonation and for land-use planning. Structural surveys in the urban area of San [...] Read more.
The southeastern flank of Mt. Etna is affected by the presence of active faults capable of adapting to deformation through both seismic slip and aseismic creep, posing challenges for seismic microzonation and for land-use planning. Structural surveys in the urban area of San Gregorio di Catania revealed a ~1 km long, N–S trending secondary fracture zone with an extensional component, inducing progressive damage to buildings and infrastructure. To characterize this scarcely visible structure, passive seismic single-station surveys processed with Horizontal-to-Vertical Spectral Ratio (HVSR) tecnique were integrated with Multichannel Analysis of Surface Waves (MASW). The HVSR data enabled the mapping of the spatial distribution of resonance frequencies, tracking an anomalous trend in the seismic bedrock geometry and depth directly correlatable with the presence of the secondary fracture zone. Directional analyses exhibit systematic preferential orientations of resonance peaks near the fracture corridor, confirming a rigorous structural control and a tectonic origin for the recorded anomalies. Furthermore, reconstructed 2D impedance contrast sections show distinct discontinuities and a local westward dislocation of the main seismo-stratigraphic interface across the deformation zone. The lack of correlated instrumental seismicity supports the interpretation that the displacement is primary accommodated via aseismic fault creep. Methodologically, these findings demonstrate that the passive seismic method provides a highly effective, non-invasive approach for identifying hard-to-detect tectonic structures that remain unobliterated by dense urbanization. Ultimately, these results offer critical, actionable constraints for seismic microzonation and urban land-use setback zoning. Full article
46 pages, 4653 KB  
Review
Gastrointestinal Tract Remodeling by Dietary Polysaccharides Mechanistic Insights in Colitis—A Review
by Afifa Aziz, Muhammad Zeeshan Adil, Muqadas Altaf, Min Wang and Kit-Leong Cheong
Foods 2026, 15(13), 2267; https://doi.org/10.3390/foods15132267 (registering DOI) - 24 Jun 2026
Abstract
The increased global prevalence of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic relapsing inflammatory condition of the gastrointestinal tract that creates a substantial socioeconomic burden. Existing pharmacotherapeutic treatments primarily target inflammatory signaling cascades and have [...] Read more.
The increased global prevalence of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic relapsing inflammatory condition of the gastrointestinal tract that creates a substantial socioeconomic burden. Existing pharmacotherapeutic treatments primarily target inflammatory signaling cascades and have disadvantages because of the side effects of drugs, reduced long-term efficacy, and high cost, necessitating the development of safe and sustainable adjunctive therapies. This review synthesizes mechanistic advances regarding dietary polysaccharides as bioactive agents that may have the capacity to induce remodeling of inflamed gastrointestinal tract in colitis and could be an adjunctive strategy as functional food ingredients due to their various biological activities in the management of colitis. Polysaccharides alleviate colitis through several interconnected pathways. First, they correct the gut dysbiosis by enriching beneficial taxa such as Lactobacillus, Bifidobacterium, and Akkermansia muciniphila. Second, fermentation of polysaccharides produces short-chain fatty acids (SCFAs), particularly butyrate, which serve as the primary energy source for colonocytes. Third, they restore intestinal barrier integrity by upregulating tight junction proteins such as ZO-1, occludin, and claudin, also performing pro-inflammatory cascade inhibition and elimination of oxidative stress via Nrf2/HO-1 activation The relationship between structural properties of polysaccharides based on molecular weight, monosaccharide composition, and biological functions of chemically modified dietary polysaccharides in colitis is studied. Dietary polysaccharides are explored here not as replacements for pharmacotherapy but as potential adjunctive or functional food-based interventions that may complement existing treatments as safe, multitargeted, and cost-effective interventions in prevention or long-term management of colitis and IBD. This review presents dietary polysaccharides function not as passive dietary fibers but as bioactive, multi-targeted, structurally dependent agents capable of restoring intestinal homeostasis, suggesting them as potentially safe, adjunctive interventions. Full article
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17 pages, 272 KB  
Review
Early-Phase Quadriceps Activation After Knee Surgery: A Narrative Review of Current Rehabilitation Interventions and Identification of an Unmet Clinical Need
by Abdulmajeed Alfayyadh
J. Clin. Med. 2026, 15(13), 4903; https://doi.org/10.3390/jcm15134903 (registering DOI) - 24 Jun 2026
Abstract
Arthrogenic muscle inhibition (AMI), neurophysiological suppression of voluntary quadriceps activation triggered by joint effusion and inflammation, is consistently initiated within hours of any form of knee surgery. If not actively counteracted during the first two postoperative weeks, AMI may drive a cascade of [...] Read more.
Arthrogenic muscle inhibition (AMI), neurophysiological suppression of voluntary quadriceps activation triggered by joint effusion and inflammation, is consistently initiated within hours of any form of knee surgery. If not actively counteracted during the first two postoperative weeks, AMI may drive a cascade of neuromuscular, morphological, and biomechanical deficits that can persist for years, substantially increasing the risk of post-traumatic osteoarthritis, reinjury, and long-term functional disability. Emerging evidence indicates that preoperative patient-related factors, including baseline quadriceps strength, age, body mass index, and physical fitness, further modulate the rehabilitation response and should be considered in planning early postoperative protocols. This narrative review, which was not designed as a systematic review or meta-analysis and therefore does not include formal quality assessment or pooled statistical analysis, evaluates evidence for seven early-phase (0–2 weeks postoperative) knee muscle activation interventions: neuromuscular electrical stimulation (NMES), isometric quadriceps exercise, blood flow restriction (BFR) training, electromyographic (EMG) biofeedback, open and closed kinetic chain (OKC/CKC) exercise, cryotherapy, and continuous passive motion (CPM). Findings are synthesized against six clinically relevant dimensions, safety in the 0–2 week window, home-based usability, capacity to overcome AMI, requirement for volitional effort, objective monitoring capability, and progressive resistance, to characterize a consistent pattern: no single existing modality simultaneously meets all combined requirements for home deployment, volitional engagement, objective monitoring, and progressive resistance from postoperative day one. This collective unmet need provides direction for future device development and clinical research. Full article
(This article belongs to the Special Issue Clinical Updates of Physical Therapy in Rehabilitation)
23 pages, 3261 KB  
Article
A Comparative Techno-Economic Assessment of Active and Passive Building Strategies: Energy Performance, Thermal Comfort, and LCOE Analysis
by Gizem Nur Bulanık Durmuş
Buildings 2026, 16(13), 2496; https://doi.org/10.3390/buildings16132496 (registering DOI) - 24 Jun 2026
Abstract
This study comparatively examines the effects of different active and passive energy strategies on energy performance, carbon emission reduction, economic feasibility, and thermal comfort potential in a university building in Ankara. This study uses a university building with 8760 h of recorded operational [...] Read more.
This study comparatively examines the effects of different active and passive energy strategies on energy performance, carbon emission reduction, economic feasibility, and thermal comfort potential in a university building in Ankara. This study uses a university building with 8760 h of recorded operational electricity consumption data as a real-world reference case and evaluates different retrofit strategies through dynamic building energy simulations. Simulation results were evaluated not only in terms of total energy consumption but also in terms of operational carbon emissions, levelized cost of energy (LCOE/LCOSE), and the potential for improving indoor temperature stability through passive design strategies. The results show that PV system integration provides the highest energy and carbon reduction performance by reducing the net grid electricity consumption by 89.76%. Among passive systems, the Trombe wall scenario provided the highest energy savings and the lowest LCOSE value. PCM application stood out in terms of indoor temperature stability potential, while the green roof system contributed to temperature control, especially during the summer. In addition, an economic sensitivity analysis based on the discount rate was carried out to reveal the strengths and weaknesses of the proposed strategies in terms of sustainable building design. The study contributes to the comparative analysis of active and passive retrofit strategies in university buildings by offering an integrated and multi-dimensional evaluation approach supported by real operational data. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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20 pages, 708 KB  
Article
Decoupling the Dual Impact of NISQ Noise on Quantum Adversarial Robustness
by Haoran Wang, Shaoliang Ye, Shaowei Wang, Hanyi Wang, Zhenbo Shi and Wei Yang
Entropy 2026, 28(7), 719; https://doi.org/10.3390/e28070719 (registering DOI) - 24 Jun 2026
Abstract
As quantum machine learning modules become increasingly integrated into NISQ-era infrastructures, it remains unclear whether intrinsic device noise can be regarded as a passive defense against adversarial examples, or whether it in fact introduces a new attack surface. To answer this question, we [...] Read more.
As quantum machine learning modules become increasingly integrated into NISQ-era infrastructures, it remains unclear whether intrinsic device noise can be regarded as a passive defense against adversarial examples, or whether it in fact introduces a new attack surface. To answer this question, we propose a noise-aware four-path evaluation protocol that decouples the noise assumed at attack generation from the noise present at inference, and we systematically test it on a 4-qubit variational quantum classifier over four datasets with depolarizing probabilities in the range p[0,0.3], using both standard gradient attacks and expectation over transformation (EOT)-based attacks. The results show that for some datasets, higher noise does suppress attacks, whereas for others attacks remain effective even at p=0.3, and in several cases a moderate noise level even maximizes the attack success rate. Moreover, we find that adversarial examples generated under moderate noise often attack the clean model more successfully than those generated in an ideal setting, demonstrating that noise can be actively exploited by an adversary to discover more transferable adversarial directions. Therefore, ambient noise should not be treated as a built-in security guarantee, and future quantum machine learning (QML) robustness evaluations must explicitly model such noise-aware threats. Full article
(This article belongs to the Special Issue Quantum Information Security)
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19 pages, 8165 KB  
Article
Volitional EMG Control of a Novel Powered Ankle Prosthesis: A Case Series on Muscle Selectivity and Biomechanical Consequences
by Faranak Rostamjoud, Mohamed Abdelbar, Friðrika Björk Þorkelsdóttir, Sophie Thiele, Anna Lára Ármannsdóttir, Atli Örn Sverrisson, Sigurður Brynjólfsson and Kristín Briem
Bioengineering 2026, 13(7), 722; https://doi.org/10.3390/bioengineering13070722 (registering DOI) - 24 Jun 2026
Abstract
This study investigated the feasibility and biomechanical effects of volitional electromyography (EMG)-based control of a powered transtibial ankle prosthesis. Four male participants completed static and dynamic EMG assessments and gait analysis while using both their prescribed passive prosthesis and an EMG-controlled powered prototype [...] Read more.
This study investigated the feasibility and biomechanical effects of volitional electromyography (EMG)-based control of a powered transtibial ankle prosthesis. Four male participants completed static and dynamic EMG assessments and gait analysis while using both their prescribed passive prosthesis and an EMG-controlled powered prototype during level walking at self-selected and fast speeds, as well as ramp ascent and descent. Selective activation of residual tibialis anterior and gastrocnemius muscles was quantified using a co-contraction index, and lower-limb kinematics and kinetics were compared between prosthetic conditions. Participants were able to generate task-dependent residual muscle activity, supporting the feasibility of EMG-based volitional control. However, muscle selectivity was reduced during dynamic tasks, with higher co-contraction during gait than during seated static contractions, and substantial inter-subject variability was observed. Compared to the prescribed passive prosthesis, the EMG-controlled prototype generally produced lower prosthetic-side ankle range of motion and ankle power, although ankle moments were sometimes slightly greater. These findings suggest that EMG control is feasible, but that future controller design must remain flexible to individual users’ neuromuscular abilities and dynamic control limitations. The results provide important guidance for the development and testing of more adaptive, personalized, and functionally effective EMG-controlled prosthetic ankle systems. Full article
(This article belongs to the Special Issue Biomechanical Assessment in Rehabilitation and Performance)
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17 pages, 1889 KB  
Article
Improving UV Stability of SiO2/SiNx-Passivated Silicon Photodiodes Through Shallow Junction Implantation and Oxide Regrowth
by Michael N. Getz, Ozhan Koybasi, Fredrik Edhborg, Ørnulf Nordseth, Steven Hesse, Tobias Pohl, Marco Povoli, Stefan Källberg, Lutz Werner, Erkki Ikonen and Jarle Gran
Sensors 2026, 26(13), 3991; https://doi.org/10.3390/s26133991 (registering DOI) - 24 Jun 2026
Abstract
Induced-junction silicon photodiodes based on SiO2/SiNx surface passivation are attractive for high-accuracy radiometry, but their use in the deep ultraviolet is limited by UV-induced degradation of the dielectric stack. In this work, we investigate the degradation of SiO2/SiN [...] Read more.
Induced-junction silicon photodiodes based on SiO2/SiNx surface passivation are attractive for high-accuracy radiometry, but their use in the deep ultraviolet is limited by UV-induced degradation of the dielectric stack. In this work, we investigate the degradation of SiO2/SiNx-passivated p-type silicon photodiodes under UV irradiation and evaluate strategies for improving stability through shallow implanted junctions and oxide processing. Capacitance–voltage measurements on MIS capacitors and lifetime measurements on symmetrically passivated wafers show that UV exposure causes a rapid reduction in effective dielectric charge and carrier lifetime, followed by saturation at higher dose, consistent with filling of a finite population of electrically active trap states. Induced-junction photodiodes exhibit rapid photocurrent loss at 222 nm and, in some cases, eventual collapse, indicating that the remaining effective dielectric charge is insufficient to sustain the induced junction. To maintain junction functionality after UV exposure, shallow As- and Sb-implanted junctions are employed, resulting in an initial reduction during 222 nm exposure followed by stabilization at around 80–85% of the initial value up to the highest tested dose of 200 J/cm2. Further improvement is achieved by stripping and regrowing the implanted screen oxide before SiNx deposition, yielding nearly unchanged photocurrent after prolonged 222 nm exposure up to ca. 500 J/cm2. These results show that UV stability can be substantially improved by reducing device dependence on dielectric-induced inversion and by improving post-implantation interfacial oxide quality. Full article
(This article belongs to the Section Electronic Sensors)
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22 pages, 4320 KB  
Article
Design and Prototyping a Novel Hybrid Shoulder Exoskeleton
by Joel Quarnstrom, Abram Smith, Owen Barragan, Adrian Toquothty and Yujiang Xiang
Biomimetics 2026, 11(7), 442; https://doi.org/10.3390/biomimetics11070442 (registering DOI) - 24 Jun 2026
Abstract
Shoulder injuries due to labor-related lifting tasks are widespread in manufacturing and logistics companies. Prolonged shifts and repetitive motions lead to muscle fatigue, significantly elevating the risk of both acute accidents and chronic musculoskeletal disorders. Many passive exoskeletons which use springs to provide [...] Read more.
Shoulder injuries due to labor-related lifting tasks are widespread in manufacturing and logistics companies. Prolonged shifts and repetitive motions lead to muscle fatigue, significantly elevating the risk of both acute accidents and chronic musculoskeletal disorders. Many passive exoskeletons which use springs to provide lifting assistance have been commercialized, and many active exoskeletons have been researched. The drawback to passive exoskeletons is the larger the lifting force that they produce, the larger the force required to lower the arms. This contributes to tiring the user. Conversely, active exoskeletons require substantial energy to provide meaningful torque. Furthermore, they pose a safety risk; a sudden power failure could result in an instantaneous loss of support, potentially causing the user to drop a heavy load and sustain injury. This research project proposes a hybrid exoskeleton with a parallel elastic actuator that uses a motorized helical actuator which can be tuned to improve lifting performance. This paper evaluates the kinematics and statics of the proposed exoskeleton, details the design and implementation of the electrical control system, shows mechanism optimization of the mechanical advantage profile, and validates the concept through the construction and experimental testing of a functional prototype. Full article
(This article belongs to the Special Issue Advanced Service Robots: Exoskeleton Robots 2026)
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10 pages, 539 KB  
Viewpoint
Small Is Beautiful: Is ctDNA Ready for Routine Implementation in Cancer Management?
by Caroline Bailleux, Jean-Marc Ferrero, Rym Bouriga, Loic Trapani, Baharia Mograbi, Jocelyn Gal and Gérard Milano
Cancers 2026, 18(13), 2034; https://doi.org/10.3390/cancers18132034 (registering DOI) - 23 Jun 2026
Abstract
Circulating tumor DNA (ctDNA) has emerged as a transformative tool in cancer diagnostics, enabling the non-invasive detection of tumor-derived DNA fragments released into the bloodstream through cellular lysis or active secretion. ctDNA measurement has demonstrated its clinical usefulness, including early cancer detection, identification [...] Read more.
Circulating tumor DNA (ctDNA) has emerged as a transformative tool in cancer diagnostics, enabling the non-invasive detection of tumor-derived DNA fragments released into the bloodstream through cellular lysis or active secretion. ctDNA measurement has demonstrated its clinical usefulness, including early cancer detection, identification of resistance mechanisms, and screening of asymptomatic individuals. In addition to prognosis, ctDNA analysis is increasingly used to guide adaptive treatment strategies by detecting minimal residual disease and tracking tumor evolution in real time. Recent advances in artificial intelligence are poised to further enhance the clinical impact of ctDNA, transforming it from a passive monitoring biomarker into a dynamic molecular sensor integrated into predictive clinical decision models. However, broad implementation of ctDNA-based assays in routine practice requires rigorous prospective validation, cross-platform standardization, and regulatory approval to unlock its full potential in precision oncology. Full article
(This article belongs to the Section Cancer Biomarkers)
25 pages, 43941 KB  
Article
Plastic-Pollution Mapping Criteria and Examples
by Brian G. Hoover, Cesar H. Ornelas-Rascon and Lena M. Hoover
Sustainability 2026, 18(13), 6394; https://doi.org/10.3390/su18136394 (registering DOI) - 23 Jun 2026
Abstract
Plastic pollution is a problem for many municipalities, water authorities, and industries, including transportation, energy, agriculture, fisheries, real estate, tourism, hospitality, insurance, and healthcare. Efforts to understand and mitigate plastic pollution would benefit from a dedicated map satisfying basic criteria including traceability, scalability, [...] Read more.
Plastic pollution is a problem for many municipalities, water authorities, and industries, including transportation, energy, agriculture, fisheries, real estate, tourism, hospitality, insurance, and healthcare. Efforts to understand and mitigate plastic pollution would benefit from a dedicated map satisfying basic criteria including traceability, scalability, spatio-temporal resolution, and data flexibility. This article details and demonstrates how several existing pollution maps satisfy these criteria and makes recommendations on their use for specific activities, including temporal monitoring, root-cause analysis (RCA), cleanups, and tourism guides. Advantages of using plastic density rather than piecewise logs as the primary data format are highlighted, in particular feasible memory requirements and access to cloud data. Environmental plastic mapping by passive optical sensors, which offer the potential of comprehensive qualified data, is also surveyed, including demonstration of an original shortwave infrared (SWIR) polarization imager, and dynamic plastic pollution monitoring is demonstrated through the application-programming interface (API) of the Google Maps platform utilizing both sensor and published survey data. Full article
(This article belongs to the Section Pollution Prevention, Mitigation and Sustainability)
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19 pages, 5072 KB  
Article
Characterizing Spatiotemporal Hydrological Responses During Extreme Flooding: A Residual Analysis Using SMAP Data
by Hashani Abeygunasekara, Badal Pokharel and Samsung Lim
ISPRS Int. J. Geo-Inf. 2026, 15(7), 277; https://doi.org/10.3390/ijgi15070277 (registering DOI) - 23 Jun 2026
Abstract
Coarsely gridded Land Surface Models (LSMs) often smooth over sub-grid spatial heterogeneity and non-linear surface soil moisture dynamics during extreme-precipitation events. This study introduces a clustering-based Soil Moisture Active Passive (SMAP) residual framework, evaluating the spatiotemporal discrepancies between 3 km SMAP Level 2 [...] Read more.
Coarsely gridded Land Surface Models (LSMs) often smooth over sub-grid spatial heterogeneity and non-linear surface soil moisture dynamics during extreme-precipitation events. This study introduces a clustering-based Soil Moisture Active Passive (SMAP) residual framework, evaluating the spatiotemporal discrepancies between 3 km SMAP Level 2 (SMAP-L2) retrievals and 9 km SMAP Level 4 (SMAP-L4) data-assimilation products within the Yanco study region during the extreme March 2021 floods in New South Wales, Australia. By applying k-means clustering to the residual time series, we partitioned the landscape into three distinct hydrological response patterns: a Low-Residual Baseline (64.5%), a Persistent Positive Anomaly (20.7%) indicative of unmodeled inundation, and a Transient Negative Anomaly (14.8%) representing rapid drainage. Consequently, 35.5% of the usable analysis area exhibited temporal trajectories that diverged significantly from model expectations, highlighting profound geographic heterogeneity in surface wetting and retention that cannot be captured by uniform precipitation inputs alone. Benchmarking the satellite-derived time series against the Yanco in situ network provided critical context for cross-scale variations, illustrating general agreement in overarching temporal trends despite the inherent scale mismatch. Ultimately, this approach leverages residual dynamics as a scalable spatial diagnostic, offering a robust, data-driven method to map localized flood responses that are typically obscured by broad-scale model parameters. Full article
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