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41 Results Found

  • Case Report
  • Open Access
1 Citations
3,538 Views
11 Pages

19 December 2024

Introduction: A Warthin tumor is a benign salivary gland neoplasm, mostly found in the parotid gland. The number of reported Warthin tumors has increased over the years due to better diagnostic modalities and health system modernization. Warthin tumo...

  • Case Report
  • Open Access
1 Citations
3,401 Views
9 Pages

Tumor-to-Tumor Metastasis: Dissemination of Cutaneous Squamous Cell Carcinoma Involving Parotid Warthin Tumor—Case Report

  • Michał Gontarz,
  • Krystyna Gałązka,
  • Krzysztof Gąsiorowski,
  • Jakub Bargiel,
  • Tomasz Marecik,
  • Paweł Szczurowski and
  • Grażyna Wyszyńska-Pawelec

Warthin tumors (WTs) are the second most common salivary gland tumors, most commonly found in the tail of the parotid gland. The lymphoid components of a WT may also serve as a site for tumor-to-tumor metastasis. This report describes the metastasis...

  • Review
  • Open Access
12 Citations
7,656 Views
17 Pages

23 February 2024

Warthin’s tumor is the second most frequent neoplasm next to pleomorphic adenoma in the salivary gland, mostly in the parotid gland. The epithelial cells constituting a tumor are characterized by the presence of mitochondria that undergo struct...

  • Review
  • Open Access
48 Citations
17,288 Views
14 Pages

Current Trends and Controversies in the Management of Warthin Tumor of the Parotid Gland

  • Miquel Quer,
  • Juan C. Hernandez-Prera,
  • Carl E. Silver,
  • Maria Casasayas,
  • Ricard Simo,
  • Vincent Vander Poorten,
  • Orlando Guntinas-Lichius,
  • Patrick J. Bradley,
  • Wai Tong-Ng and
  • Alfio Ferlito
  • + 10 authors

Purpose: To review the current options in the management of Warthin tumors (WTs) and to propose a working management protocol. Methods: A systematic literature search was conducted using PubMed and ScienceDirect database. A total of 141 publications...

  • Interesting Images
  • Open Access
985 Views
6 Pages

22 October 2025

Warthin’s tumor is a benign salivary gland neoplasm that can exhibit intense FDG uptake, potentially mimicking malignant lesions on oncologic imaging. We report a case of a 78-year-old man undergoing staging for suspected lung cancer, in whom a...

  • Case Report
  • Open Access
8,828 Views
8 Pages

Unilateral Deforming Warthin’s Tumor: Case Report and Literature Review

  • Ioana Maria Porfire,
  • Nicoleta Pers,
  • Anda Apostol and
  • Silviu Albu

10 September 2020

Warthin’s tumor (WT) is the second most common benign tumor of the parotid gland. Located almost exclusively in the parotid gland and presenting a slow growth rate, WT usually does not exceed 4 cm and rarely benefits from early surgical treatment. Th...

  • Article
  • Open Access
1 Citations
1,664 Views
13 Pages

The Role of MRI Radiomics Using T2-Weighted Images and the Apparent Diffusion Coefficient Map for Discriminating Between Warthin’s Tumors and Malignant Parotid Gland Tumors

  • Delia Doris Donci,
  • Carolina Solomon,
  • Mihaela Băciuț,
  • Cristian Dinu,
  • Sebastian Stoia,
  • Georgeta Mihaela Rusu,
  • Csaba Csutak,
  • Lavinia Manuela Lenghel and
  • Anca Ciurea

12 February 2025

Background/Objectives: Differentiating between benign and malignant parotid gland tumors (PGT) is essential for establishing the treatment strategy, which is greatly influenced by the tumor’s histology. The objective of this study was to evalua...

  • Article
  • Open Access
10 Citations
3,727 Views
11 Pages

Long-Term Outcomes of Radiofrequency Ablation for Treatment of Cystic Warthin Tumors versus Solid Warthin Tumors

  • Chih-Hung Cha,
  • Sheng-Dean Luo,
  • Pi-Ling Chiang,
  • Wei-Chih Chen,
  • Yu-Cheng Tung,
  • Yan-Ye Su and
  • Wei-Che Lin

Background: To describe the long-term outcomes of radiofrequency ablation (RFA) of parotid Warthin tumors that have different consistencies and locations. Methods: We reviewed ten patients with Warthin tumors undergoing RFA treatment from 2016 to 201...

  • Article
  • Open Access
11 Citations
4,322 Views
13 Pages

Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors

  • Robert Mandic,
  • Abbas Agaimy,
  • Daniel Pinto-Quintero,
  • Katrin Roth,
  • Afshin Teymoortash,
  • Hans Schwarzbach,
  • Christine G. Stoehr,
  • Fiona R. Rodepeter,
  • Boris A. Stuck and
  • Michael Bette

29 April 2020

The Warthin tumor represents the second most frequent benign tumor of the parotid gland and is characterized by the presence of oncocytes rich in structurally and functionally altered mitochondria. Next to its role in metabolism, glyceraldehyde-3-pho...

  • Article
  • Open Access
7 Citations
2,755 Views
11 Pages

Preoperative Diagnosis of Warthin Tumors Combining Cytological, Clinical and Ultrasonographic Information within a Multidisciplinary Approach in a Lump Clinic

  • Paolo Fois,
  • Luca Mureddu,
  • Alessandra Manca,
  • Simona Varrucciu,
  • Claudia Crescio,
  • Roberto Gallus,
  • Davide Rizzo,
  • Antonio Cossu and
  • Francesco Bussu

29 June 2023

(1) Background: Warthin tumors account for about 20% of all benign salivary tumors, approaching 50% if we consider only the parotid gland. Wait and see is considered a reasonable option, but the diagnosis should be certain. Diagnosis can be based on...

  • Article
  • Open Access
4 Citations
1,700 Views
13 Pages

Could Obesity Be Related to the Increasing Incidence of Warthin Tumors?

  • Michał Gontarz,
  • Jakub Bargiel,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik,
  • Paweł Szczurowski,
  • Andrei Hramyka,
  • Joanna Kuczera,
  • Agata Wieczorkiewicz and
  • Grażyna Wyszyńska-Pawelec

21 August 2024

Background: The number of patients diagnosed with Warthin tumors (WTs) has increased significantly in recent years. The association of obesity as measured by body mass index (BMI) with the incidence of WTs remains unclear. This retrospective study ai...

  • Interesting Images
  • Open Access
4 Citations
3,964 Views
4 Pages

8 November 2021

Salivary gland tumors are rare neoplasms which vary in terms of origin and malignant potential. 2-[18F]-fluoro-2-deoxy-d-glucose (FDG)-positron emission tomography (PET) has limited ability to differentiate between different types of salivary gland t...

  • Article
  • Open Access
6 Citations
3,254 Views
11 Pages

Evaluation of Fine Needle Aspiration Cytopathology in Salivary Gland Tumors under Milan System: Challenges, Misdiagnosis Rates, and Clinical Recommendations

  • Yi-Tien Huang,
  • Chen-Yu Ho,
  • Chun-Yen Ou,
  • Cheng-Chih Huang,
  • Wei-Ting Lee,
  • Shu-Wei Tsai,
  • Heng-Jui Hsu,
  • David Shang-Yu Hung,
  • Chien-Sheng Tsai and
  • Chien-Chin Chen
  • + 4 authors

(1) Background: Salivary gland tumors are rare in the head and neck. To determine the need and extent of surgical intervention, fine needle aspiration (FNA) is a widely accepted tool to approach salivary gland lesions. However, the FNA cytology varie...

  • Article
  • Open Access
2 Citations
2,202 Views
14 Pages

Novel Discovery of the Somatostatin Receptor (SSTR2) in Pleomorphic Adenomas via Immunohistochemical Analysis of Tumors of the Salivary Glands

  • Felix Johnson,
  • Benedikt Hofauer,
  • Markus Wirth,
  • Barbara Wollenberg,
  • Fabian Stögbauer,
  • Susan Notohamiprodjo,
  • Bernhard Haller,
  • Robin Reschke,
  • Andreas Knopf and
  • Ulrich Strassen

1 August 2023

Reliable preoperative diagnosis between salivary gland tumor entities is difficult. In this monocentric retrospective study, we examined the somatostatin receptor 2 (SSTR2) status of salivary gland tumors after salivary gland tumor resection via immu...

  • Article
  • Open Access
41 Citations
5,896 Views
14 Pages

Can Magnetic Resonance Radiomics Analysis Discriminate Parotid Gland Tumors? A Pilot Study

  • Michela Gabelloni,
  • Lorenzo Faggioni,
  • Simona Attanasio,
  • Vanina Vani,
  • Antonio Goddi,
  • Sara Colantonio,
  • Danila Germanese,
  • Claudia Caudai,
  • Luca Bruschini and
  • Emanuele Neri
  • + 2 authors

3 November 2020

Our purpose is to evaluate the performance of magnetic resonance (MR) radiomics analysis for differentiating between malignant and benign parotid neoplasms and, among the latter, between pleomorphic adenomas and Warthin tumors. We retrospectively eva...

  • Systematic Review
  • Open Access
7 Citations
2,873 Views
12 Pages

12 December 2022

Recently, contrast-enhanced ultrasound (CEUS) has become a promising tool in distinguishing benign from malignant parotid gland tumors. However, its usefulness in differentiating various benign parotid tumors has not been determined so far. This stud...

  • Article
  • Open Access
31 Citations
4,007 Views
12 Pages

Epidemiology of Primary Epithelial Salivary Gland Tumors in Southern Poland—A 26-Year, Clinicopathologic, Retrospective Analysis

  • Michał Gontarz,
  • Jakub Bargiel,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik,
  • Paweł Szczurowski,
  • Jan Zapała and
  • Grażyna Wyszyńska-Pawelec

13 April 2021

(1) Background: Epidemiological studies of epithelial salivary gland neoplasms are difficult to conduct effectively due to tumor rarity, histological heterogeneity, tumor location diversity, and a lack of national registries collecting data. This stu...

  • Article
  • Open Access
6 Citations
2,925 Views
12 Pages

4 March 2022

Aim: The aim of this prospective study is to identify quantitative intravoxel incoherent motion and dynamic contrast-enhanced magnetic resonance imaging parameters of the most frequent benign parotid tumors, compare their utility and diagnostic accur...

  • Article
  • Open Access
1 Citations
1,831 Views
9 Pages

Title Expression of FOXO3 and MAPK1 Genes in Patients with Benign Salivary Gland Tumors

  • Katarzyna Kolary-Siekierska,
  • Piotr Niewiadomski,
  • Wojciech Namieciński and
  • Jarosław Miłoński

29 December 2023

Pleomorphic adenomas (PAs) and Warthin tumors (WTs) are the most common benign tumors that occur in the salivary gland. PA has a tendency towards malignant transformation. Thus, searching for new methods to diagnose salivary gland tumors and treatmen...

  • Article
  • Open Access
1 Citations
2,464 Views
15 Pages

Novel Detection of Pleomorphic Adenomas via Analysis of 68Ga-DOTATOC PET/CT Imaging

  • Felix Johnson,
  • Marcel Kloppenburg,
  • Benedikt Hofauer,
  • Barbara Wollenberg,
  • Cosima C. Hoch,
  • Fabian Stögbauer,
  • Bernhard Haller,
  • Andreas Knopf,
  • Ulrich Strassen and
  • Susan Notohamiprodjo

23 July 2024

Introduction: Currently, the diagnosis of salivary gland tumors using imaging techniques is unreliable. Methods: In this monocentric retrospective study, we examined patients who received a 68Ga-DOTATOC PET/CT and subsequently underwent a salivary gl...

  • Review
  • Open Access
1 Citations
1,814 Views
17 Pages

The Impact of Inflammation on the Etiopathogenesis of Benign Salivary Gland Tumors: A Scoping Review

  • Konrad Szydłowski,
  • Michał Puchalski,
  • Stanisław Ołdziej,
  • Agnieszka Kasprzyk-Tryk,
  • Andrzej Skorek and
  • Dmitry Tretiakow

22 November 2024

Salivary gland tumors are rare head and neck tumors constituting up to 6% of all head and neck neoplasms; despite being mostly benign, these tumors present in diverse histological subtypes, making them challenging to diagnose and treat. Our research...

  • Article
  • Open Access
1,526 Views
12 Pages

A Six-Year Examination of the Influence of Surgical Technique and Intraoperative Intraglandular Clostridium Botulinum Toxin Application in Salivary Gland Tumor Operations

  • Felix Johnson,
  • Nora-Maria Burian,
  • Matthias Santer,
  • Verena Strasser,
  • Teresa Steinbichler,
  • Benedikt Hofauer,
  • Anna Stenzl,
  • Johanna Klarer,
  • Robin Lochbaum and
  • Amir Bolooki
  • + 3 authors

16 November 2024

Introduction: Salivary gland tumor operations are associated with complications including facial nerve dysfunction (FND) and salivary fistula. The objective of this study was to investigate the effect of extracapsular dissection (ECD) and the applica...

  • Article
  • Open Access
4 Citations
3,008 Views
9 Pages

Minimal Margin Surgery and Intraoperative Neuromonitoring in Benign Parotid Gland Tumors: Retrospective Clinical Study

  • Eva Aurora Massimilla,
  • Giovanni Motta,
  • Michelangelo Magaldi,
  • Marco Montella,
  • Gaetana Messina,
  • Domenico Testa,
  • Elena Cantone and
  • Gaetano Motta

3 October 2022

Extracapsular dissection (ECD) was introduced for the removal of superficial and small benign parotid tumors. According to a recent proposal, ECD is reserved for tumors that are 3 cm or less, mobile, and close to the parotid borders in cases of pleom...

  • Article
  • Open Access
6 Citations
2,749 Views
15 Pages

Apparent Diffusion Coefficient (ADC) Histogram Analysis in Parotid Gland Tumors: Evaluating a Novel Approach for Differentiation between Benign and Malignant Parotid Lesions Based on Full Histogram Distributions

  • Tobias Hepp,
  • Wolfgang Wuest,
  • Rafael Heiss,
  • Matthias Stefan May,
  • Markus Kopp,
  • Matthias Wetzl,
  • Christoph Treutlein,
  • Michael Uder and
  • Marco Wiesmueller

The aim of this study was to assess the diagnostic value of ADC distribution curves for differentiation between benign and malignant parotid gland tumors and to compare with mean ADC values. 73 patients with parotid gland tumors underwent head-and-ne...

  • Article
  • Open Access
15 Citations
2,563 Views
11 Pages

Support Tools in the Differential Diagnosis of Salivary Gland Tumors through Inflammatory Biomarkers and Radiomics Metrics: A Preliminary Study

  • Umberto Committeri,
  • Simona Barone,
  • Giovanni Salzano,
  • Antonio Arena,
  • Gerardo Borriello,
  • Francesco Giovacchini,
  • Roberta Fusco,
  • Luigi Angelo Vaira,
  • Alfonso Scarpa and
  • Giovanni Dell’Aversana Orabona
  • + 5 authors

21 March 2023

Background: The purpose of this study was to investigate how the systemic inflammation response index (SIRI), systemic immune-inflammation index (SII), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), and radiomic metrics (quant...

  • Systematic Review
  • Open Access
12 Citations
2,725 Views
17 Pages

Radiomics Analysis in Characterization of Salivary Gland Tumors on MRI: A Systematic Review

  • Kaijing Mao,
  • Lun M. Wong,
  • Rongli Zhang,
  • Tiffany Y. So,
  • Zhiyi Shan,
  • Kuo Feng Hung and
  • Qi Yong H. Ai

10 October 2023

Radiomics analysis can potentially characterize salivary gland tumors (SGTs) on magnetic resonance imaging (MRI). The procedures for radiomics analysis were various, and no consistent performances were reported. This review evaluated the methodologie...

  • Article
  • Open Access
790 Views
14 Pages

The Evaluation of Blood Prooxidant–Antioxidant Balance Indicators and Cortisol Pre- and Post-Surgery in Patients with Benign Parotid Gland Tumors: A Preliminary Study

  • Sebastian Bańkowski,
  • Jan Pilch,
  • Bartosz Witek,
  • Jarosław Markowski,
  • Wirginia Likus,
  • Michał Rozpara and
  • Ewa Sadowska-Krępa

1 August 2025

Background: The majority of parotid gland tumors are benign, e.g., pleomorphic adenoma (PA) and Warthin’s tumor (WT). From a biomedical point of view, oxidative stress is of significant importance due to its established association with the ini...

  • Article
  • Open Access
9 Citations
5,381 Views
13 Pages

Assessment of Parotid Gland Tumors by Means of Quantitative Multiparametric Ultrasound (mpUS)

  • Katharina Margherita Wakonig,
  • Markus Herbert Lerchbaumer,
  • Steffen Dommerich,
  • Heidi Olze,
  • Bernd Hamm,
  • Thomas Fischer and
  • Philipp Arens

Objective: The preoperative diagnostical differentiation of parotid gland tumor (PGT) is not always simple due to several different entities. B-mode-ultrasound (US) remains the imaging modality of choice, while histopathology serves as the gold stand...

  • Article
  • Open Access
53 Citations
5,767 Views
13 Pages

Characteristics of 5015 Salivary Gland Neoplasms Registered in the Hiroshima Tumor Tissue Registry over a Period of 39 Years

  • Kazuhiro Sentani,
  • Ikuko Ogawa,
  • Kotaro Ozasa,
  • Atsuko Sadakane,
  • Mai Utada,
  • Takafumi Tsuya,
  • Hiroki Kajihara,
  • Shuji Yonehara,
  • Yukio Takeshima and
  • Wataru Yasui

26 April 2019

Salivary gland neoplasms are uncommon, and their epidemiology in Japan has not been well described. We conducted a retrospective review of salivary gland tumors registered in the Hiroshima Tumor Tissue Registry over a period of 39 years. The subjects...

  • Article
  • Open Access
5 Citations
2,265 Views
19 Pages

Comparative Diagnostic Accuracy of Ultrasound, MRI, and Fine-Needle Aspiration Biopsy in the Preoperative Evaluation of Parotid Gland Tumors

  • Sebastian Stoia,
  • Anca Ciurea,
  • Mihaela Băciuț,
  • Simion Bran,
  • Gabriel Armencea,
  • Emil Boțan,
  • Manuela Lenghel,
  • Tiberiu Tamaș,
  • Rareș Mocan and
  • Cristian Dinu
  • + 2 authors

18 February 2025

Background: The objective of this study was to compare the value of ultrasound (US), magnetic resonance imaging (MRI), and US-guided fine-needle aspiration biopsy (FNAB) in the preoperative evaluation of parotid tumors. Methods: A three-year prospect...

  • Article
  • Open Access
2,264 Views
17 Pages

Differentiation of Salivary Gland and Salivary Gland Tumor Tissue via Raman Imaging Combined with Multivariate Data Analysis

  • Miriam C. Bassler,
  • Mona Knoblich,
  • Elena Gerhard-Hartmann,
  • Ashutosh Mukherjee,
  • Almoatazbellah Youssef,
  • Rudolf Hagen,
  • Lukas Haug,
  • Miguel Goncalves,
  • Agmal Scherzad and
  • Till Jasper Meyer
  • + 5 authors

Salivary gland tumors (SGTs) are a relevant, highly diverse subgroup of head and neck tumors whose entity determination can be difficult. Confocal Raman imaging in combination with multivariate data analysis may possibly support their correct classif...

  • Article
  • Open Access
3 Citations
4,489 Views
15 Pages

High Field MRI in Parotid Gland Tumors: A Diagnostic Algorithm

  • Chiara Gaudino,
  • Andrea Cassoni,
  • Martina Lucia Pisciotti,
  • Resi Pucci,
  • Chiara Veneroso,
  • Cira Rosaria Tiziana Di Gioia,
  • Francesca De Felice,
  • Patrizia Pantano and
  • Valentino Valentini

29 December 2024

Backgrounds: Imaging of parotid tumors is crucial for surgery planning, but it cannot distinguish malignant from benign lesions with absolute reliability. The aim of the study was to establish a diagnostic MRI algorithm to differentiate parotid tumor...

  • Article
  • Open Access
15 Citations
3,650 Views
15 Pages

The Value of Multiparametric Magnetic Resonance Imaging in the Preoperative Differential Diagnosis of Parotid Gland Tumors

  • Sebastian Stoia,
  • Manuela Lenghel,
  • Cristian Dinu,
  • Tiberiu Tamaș,
  • Simion Bran,
  • Mihaela Băciuț,
  • Emil Boțan,
  • Daniel Leucuța,
  • Gabriel Armencea and
  • Grigore Băciuț
  • + 1 author

19 February 2023

Background: The aim of the present study was to determine the value of multiparametric MRI in the preoperative differential diagnosis of parotid tumors, which is essential for therapeutic strategy selection. Methods: A three-year prospective study wa...

  • Article
  • Open Access
1 Citations
3,382 Views
15 Pages

Relative Frequency of Primary Salivary Gland Tumors: Multicenter Study of 796 Cases from Riyadh, Saudi Arabia

  • Nasser AlMaden,
  • Rawan AlYami,
  • Ahmed Almotairi,
  • Rasha Alrasheed,
  • Bader Aldawasri,
  • Mohammed Alwhabi,
  • Assem Alrumeh,
  • Nasser AlBishi,
  • Abdullah Alqarni and
  • Asma Almazyad
  • + 1 author

8 December 2024

Background and Objectives: Salivary gland tumors (SGTs) are diverse lesions with varying morphological and clinical characteristics. Limited data exist on the distribution of SGTs in Saudi Arabia. We aimed to fill this gap by examining the distributi...

  • Article
  • Open Access
342 Views
24 Pages

Benign Epithelial Salivary Neoplasms: Single-Centered Histopathologic and Clinicodemographic Romanian Retrospective Study

  • Constantin Aleodor Costin,
  • Adriana Grigoraș,
  • Elena Corina Andriescu and
  • Cornelia Amalinei

15 December 2025

Background: Epidemiological studies on benign epithelial salivary gland tumors are challenging due to their rarity, pathological heterogeneity, variable tumor locations, and the limited national data collection in Romania. Our study aimed at the eval...

  • Article
  • Open Access
1 Citations
2,541 Views
10 Pages

The Clinical and Surgical Characteristics of Parotid Tumors with Parapharyngeal Space Involvement—A Multicenter Experience of the Polish Salivary Network

  • Dominik Stodulski,
  • Bogusław Mikaszewski,
  • Paweł Witkowski,
  • Ewelina Bartkowiak,
  • Wioletta Pietruszewska,
  • Izabela Olejniczak,
  • Jarosław Markowski,
  • Aleksandra Piernicka-Dybich,
  • Paweł Burduk and
  • Małgorzata Wierzbicka
  • + 7 authors

5 August 2024

Backgrounds/Objectives: Parotid gland tumors (PGTs) with parapharyngeal space (PPS) involvement have a specific clinical course and they can be a great challenge for surgeons, especially due to more difficult approaches and the risk of serious compli...

  • Article
  • Open Access
156 Views
9 Pages

Clinicopathologic Features and Postoperative Outcomes of Parotidectomy: A 16-Year Retrospective Cohort Study from a Tertiary Referral Center

  • Seval Akay,
  • Ozlem Yagiz Agayarov,
  • Volkan Semiz,
  • Ulku Kucuk,
  • Ilker Burak Arslan,
  • Olcun Umit Unal and
  • Ibrahim Cukurova

Background: Parotid gland tumors pose diagnostic and surgical challenges due to their histological heterogeneity and proximity to the facial nerve. This study aimed to evaluate clinicopathological features and postoperative outcomes with a specific f...

  • Article
  • Open Access
840 Views
10 Pages

Clinical Significance of Incidentally Detected Parotid Masses on Brain MRI and PET-CT

  • Joong Seob Lee,
  • Jeong In Jang,
  • Jee Hye Wee,
  • Jeong Wook Kang,
  • Ho Suk Kang,
  • Mi Jung Kwon and
  • Heejin Kim

14 November 2025

Background/Objectives: Parotid incidentalomas are increasingly detected during brain MRI and PET-CT, particularly in patients with serious diseases such as cancer. This study aimed to evaluate the clinical significance of incidentally identified paro...

  • Article
  • Open Access
2,349 Views
11 Pages

1 August 2023

The study aimed to compare 15 cases of mucoepidermoid carcinoma (MEC) and 15 cases of hyalinizing clear cell carcinoma (HCCC) using immunohistochemical staining and molecular analysis. Thirty samples were examined, and markers, including p63, CK5/6,...

  • Article
  • Open Access
6 Views
20 Pages

Clinical Behavior of Aggressive Variants of Papillary Thyroid Carcinoma: A Retrospective Case–Control Study

  • Jovan Ilic,
  • Nikola Slijepcevic,
  • Katarina Tausanovic,
  • Bozidar Odalovic,
  • Goran Zoric,
  • Marija Milinkovic,
  • Branislav Rovcanin,
  • Milan Jovanovic,
  • Matija Buzejic and
  • Vladan Zivaljevic
  • + 5 authors

22 January 2026

Background/Objectives: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. The classic variant (cPTC) is characterized by indolent behavior and excellent prognosis. However, rare subtypes of PTC most often exhibit adverse clini...

  • Article
  • Open Access
1 Citations
1,167 Views
24 Pages

Parotid Gland Tumors: An Institutional 8-Year Retrospective Study Spanning the COVID-19 Pandemic and Global Diagnostic Trends

  • Eduard Gidea-Paraschivescu,
  • Ruxandra Elena Luca,
  • Cristian Adrian Ratiu and
  • Ciprian Ioan Roi

19 October 2025

Background/Objectives: Despite the relative rarity of salivary gland tumours (SGT), they are a complex and challenging pathology. This is primarily due to the complexity of surgical treatment, the difficulty of diagnosis, and the sometimes ambiguous...