Search Results (8)

In this paper, a new light event acquisition chain in a three-gamma liquid xenon prototype for medical nuclear imaging is presented. The prototype implements the Multi-Time-Over-Threshold (MTOT) method. This method surpasses the Single-Time-Over-Threshold (STOT) by precisely determining both the number of vacuum ultraviolet (VUV) photons detected by each photomultiplier tube (PMT) and their arrival times for light signal measurement. Based on both the experimental and simulated results, the MTOT method achieved a 70% improvement in reconstructing photoelectrons (PEs) and enhanced the precision of the arrival time estimation by 20–30% compared with STOT. These results will enable an upgrade of the XEMIS2 (Xenon Medical Imaging System) camera, improving its performance as the imaged activity increases. Full article

Understanding how climatic variables impact the reference evapotranspiration (ETo) is essential for water resource management, especially considering potential fluctuations due to climate change. Therefore, we used the Sobol’ method to analyze the spatiotemporal variations of Penman–Monteith ETo sensitivity to the climatic variables: downward solar radiation, relative humidity, maximum and minimum air temperature, and wind speed. The Sobol’ indices variances were estimated by Monte Carlo integration, with sample limits set to the 2.5th and 97.5th percentiles of the daily data of 33 automatic weather stations located in the state of Mato Grosso, Brazil. The results of the Sobol’ analysis indicate considerable spatiotemporal variations in the sensitivity of ETo to climatic variables and their interactions. The dominant climatic variable responsible for ETo fluctuations in Mato Grosso is incident solar radiation (53% to 93% of annual total sensitivity—S_tot), which has a more significant impact in humid environments (70% to 90% of S_tot), as observed in the areas of the Amazon biome in the state. Air relative humidity and wind speed have higher sensitivity indices during the dry season in the Cerrado biome (savanna) areas in Mato Grosso (20% and 30% of the S_tot, respectively). Our findings show that changes in solar radiation, relative humidity, and wind speed are the main driving forces that impact the reference evapotranspiration. Full article

The Sentinel-2A and Sentinel-2B satellites, with on-board Multi-Spectral Instrument (MSI), and launched on 23 June 2015 and 7 March 2017, respectively, are very useful tools for studying ocean color, even if they were designed for land and vegetation applications. However, the use of these satellites requires a process called “atmospheric correction”. This process aims to remove the contribution of the atmosphere from the total top of atmosphere reflectance measured by the remote sensors. For the purpose of assessing this processing, seven atmospheric correction algorithms have been compared over two French coastal regions (English Channel and French Guiana): Image correction for atmospheric effects (iCOR), Atmospheric correction for OLI ‘lite’ (ACOLITE), Case 2 Regional Coast Colour (C2RCC), Sentinel 2 Correction (Sen2Cor), Polynomial-based algorithm applied to MERIS (Polymer), the standard NASA atmospheric correction (NASA-AC) and the Ocean Color Simultaneous Marine and Aerosol Retrieval Tool (OC-SMART). The satellite-estimated remote-sensing reflectances were spatially and temporally matched with in situ measurements collected by an ASD FieldSpec4 spectrophotometer. Results, based on 28 potential individual match-ups, showed that the best performance processor is OC-SMART with the highest values for the total score S_tot (16.89) and for the coefficient of correlation R² (ranging from 0.69 at 443 nm to 0.92 at 665 nm). iCOR and Sen2Cor show the less accurate performances with total score S_tot values of 2.01 and 7.70, respectively. Since the size of the in situ observation platform can be significant compared to the pixel resolution of MSI onboard Sentinel-2, it can create bias in the pixel extraction process. Thus, to study this impact, we used different methods of pixel extraction. However, there are no significant changes in results; some future research may be necessary. Full article

In this paper, the study of the influence of the matrix structure (mxm) of thin-film, rotation angle (α), magnetic field (B), and size (D) of Fe₂O₃ nanoparticle on the magnetic characteristic quantities such as the magnetization oriented z-direction (M_zE), z-axis magnetization (M_z), total magnetization (M_tot), and total entropy (S_tot) of Fe₂O₃ nanocomposites by Monte-Carlo (MC) simulation method are studied. The applied MC Metropolis code achieves stability very quickly, so that after 30 Monte Carlo steps (MCs), the change of obtained results is negligible, but for certainty, 84 MCs have been performed. The obtained results show that when the mxm and α increase, the magnetic phase transition appears with a very small increase in temperature Néel (T_Ntot). When B and D increase, T_Ntot increases very strongly. The results also show that in Fe₂O₃ thin films, T_Ntot is always smaller than with Fe₂O₃ nano and Fe₂O₃ bulk. When the nanoparticle size is increased to nearly 12 nm, then T_Ntot = T = 300 K, and between TNtot and D, there is a linear relationship: T_Ntot = −440.6 + 83D. This is a very useful result that can be applied in magnetic devices and in biomedical applications. Full article

Early diagnosis of pediatric cancer is key for adequate patient management and improved outcome. Although multiparameter flow cytometry (MFC) has proven of great utility in the diagnosis and classification of hematologic malignancies, its application to non-hematopoietic pediatric tumors remains limited. Here we designed and prospectively validated a new single eight-color antibody combination—solid tumor orientation tube, STOT—for diagnostic screening of pediatric cancer by MFC. A total of 476 samples (139 tumor mass, 138 bone marrow, 86 lymph node, 58 peripheral blood, and 55 other body fluid samples) from 296 patients with diagnostic suspicion of pediatric cancer were analyzed by MFC vs. conventional diagnostic procedures. STOT was designed after several design–test–evaluate–redesign cycles based on a large panel of monoclonal antibody combinations tested on 301 samples. In its final version, STOT consists of a single 8-color/12-marker antibody combination (CD99-CD8/_numyogenin/CD4-EpCAM/CD56/GD2/_smCD3-CD19/_cyCD3-CD271/CD45). Prospective validation of STOT in 149 samples showed concordant results with the patient WHO/ICCC-3 diagnosis in 138/149 cases (92.6%). These included: 63/63 (100%) reactive/disease-free samples, 43/44 (98%) malignant and 4/4 (100%) benign non-hematopoietic tumors together with 28/38 (74%) leukemia/lymphoma cases; the only exception was Hodgkin lymphoma that required additional markers to be stained. In addition, STOT allowed accurate discrimination among the four most common subtypes of malignant CD45⁻ CD56⁺⁺ non-hematopoietic solid tumors: 13/13 (GD2⁺⁺ _numyogenin⁻ CD271^−/+ _nuMyoD1⁻ CD99⁻ EpCAM⁻) neuroblastoma samples, 5/5 (GD2⁻ _numyogenin⁺⁺ CD271⁺⁺ _nuMyoD1⁺⁺ CD99^−/+ EpCAM⁻) rhabdomyosarcomas, 2/2 (GD2^−/+ _numyogenin⁻ CD271⁺ _nuMyoD1⁻ CD99⁺ EpCAM⁻) Ewing sarcoma family of tumors, and 7/7 (GD2⁻ _numyogenin⁻ CD271⁺ _nuMyoD1⁻ CD99⁻ EpCAM⁺) Wilms tumors. In summary, here we designed and validated a new standardized antibody combination and MFC assay for diagnostic screening of pediatric solid tumors that might contribute to fast and accurate diagnostic orientation and classification of pediatric cancer in routine clinical practice. Full article

The de-embedding of measurement fixtures is relevant for an accurate experimental characterization of radio frequency and digital electronic devices. The standard technique consists in removing the effects of the measurement fixtures by the calculation of the transfer scattering parameters (T-parameters) from the available measured (or simulated) global scattering parameters (S-parameters). The standard de-embedding is achieved by a multiple steps process, involving the S-to-T and subsequent T-to-S parameter conversion. In a typical measurement setup, two fixtures are usually placed before and after the device under test (DUT) allowing the connection of the device to the calibrated vector network analyzer coaxial ports. An alternative method is proposed in this paper: it is based on the newly developed multi-network cascading algorithm. The matrices involved in the fixture-DUT-fixture cascading gives rise to a non-linear set of equations that is in one step analytically solved in closed form, obtaining a unique solution. The method is shown to be effective and at least as accurate as the standard multi-step de-embedding one. Full article

Biogas is an alternative source of energy for fossil fuels. In the process of transforming organic materials into biogas significant amounts of valuable digestate are produced. In order to make the whole process sustainable digestate should be utilized this is a constraining factor in the development of the biogas industry. Consequently, there is an on-going search for new technologies to process digestate, allowing to broaden the range of possible ways of digestate utilization. One of such possibilities is technology of nitrogen (N) and phosphorus (P) recovery from the anaerobic digestate. In this study results of physicochemical analysis of materials flowing through the farm-scale bio-refinery producing struvite (STR) and ammonium sulphate (AS) are presented. Struvite was precipitated from the liquid fraction of digestate (LFDS). Ammonia was bound by sulphuric acid resulting in obtaining ammonium sulphate. The STR obtained was of medium purity and contained other macronutrients and micronutrients that further enhanced its agronomic value. The P recovery effectiveness, counted as the difference between the P_tot content in the material before and after STR precipitation was 43.8%. The AS was characterized by relatively low N_tot and S_tot content. The N_tot recovery efficiency reached 43.2%. The study showed that struvite precipitation and ammonia stripping technologies can be used for processing digestate however, the processes efficiency should be improved. Full article

Response Surface Methodology (RSM) is introduced to optimize the control rod positions in a pressurized water reactor (PWR) core. The widely used 3D-IAEA benchmark problem is selected as the typical PWR core and the neutron flux field is solved. Besides, some additional thermal parameters are assumed to obtain the temperature distribution. Then the total and local entropy production is calculated to evaluate the energy dissipation. Using RSM, three directions of optimization are taken, which aim to determine the minimum of power peak factor P_max, peak temperature T_max and total entropy production S_tot. These parameters reflect the safety and energy dissipation in the core. Finally, an optimization scheme was obtained, which reduced P_max, T_max and S_tot by 23%, 8.7% and 16%, respectively. The optimization results are satisfactory. Full article