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19 pages, 11978 KiB  
Article
Spatiotemporal Patterns of Greening and Their Correlation with Surface Radiative Forcing on the Tibetan Plateau from 1982 to 2021
by Junshan Guo, Kai Wu, Han Yang and Yao Shen
ISPRS Int. J. Geo-Inf. 2025, 14(6), 228; https://doi.org/10.3390/ijgi14060228 - 10 Jun 2025
Viewed by 420
Abstract
Vegetation change profoundly influences ecosystem sustainability and human activities, with solar radiation serving as a primary driver. However, the effects of surface radiative forcing (SRF) and related factors on vegetation dynamics remain poorly understood. The Tibetan Plateau, a climate-sensitive region, offers a unique [...] Read more.
Vegetation change profoundly influences ecosystem sustainability and human activities, with solar radiation serving as a primary driver. However, the effects of surface radiative forcing (SRF) and related factors on vegetation dynamics remain poorly understood. The Tibetan Plateau, a climate-sensitive region, offers a unique context to investigate these relationships. This study analyzes the association between vegetation greening and SRF on the Tibetan Plateau from 1982 to 2021. Using forecast albedo (FAL) and surface solar radiation downwards (SSRD), we calculated SRF and explored its correlation with the Normalized Difference Vegetation Index (NDVI) and land cover data. The results indicate a gradual increase in growing-season NDVI, suggesting vegetation greening. Both FAL and SSRD exhibit decreasing trends, yet neither shows a statistically significant correlation with NDVI. The correlations between FAL/SSRD and NDVI weaken with increasing altitude, declining by 0.035 × 10−1 per 500 m and 0.021 × 10−1 per 500 m, respectively. Among vegetation types, FAL correlates most strongly with shrubland NDVI and weakest with forest NDVI, while SSRD demonstrates the highest correlation with grassland NDVI and lowest with forest NDVI. The impact of SRF on NDVI changes is evident in 52.881% of the plateau, showing a positive correlation between SRF and ΔNDVI, compared to 39.589% for SSRD and ΔNDVI. This research enhances the understanding of vegetation responses to FAL, SSRD, and SRF, providing a scientific basis for ecological conservation and climate adaptation strategies, and also emphasizes radiation–vegetation feedback, providing guidance for conservation strategies in other alpine ecosystems globally, such as the Andes and Alps, where elevation gradients and vegetation-type-specific responses to radiative forcing may similarly govern ecological outcomes. Full article
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20 pages, 1173 KiB  
Article
Leptin and PAI-1 Levels Are Decreased After a Dietary Intervention in Patients with Irritable Bowel Syndrome
by Andreas-Balázs Szekely, Mohamed Nseir, Bodil Roth and Bodil Ohlsson
Int. J. Mol. Sci. 2025, 26(10), 4607; https://doi.org/10.3390/ijms26104607 - 11 May 2025
Viewed by 564
Abstract
A diet low in fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is an established treatment for irritable bowel syndrome (IBS). The starch- and sucrose-reduced diet (SSRD) is a newer, promising diet. Nutrients influence the production of gut hormones, which affect gastrointestinal motility. [...] Read more.
A diet low in fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is an established treatment for irritable bowel syndrome (IBS). The starch- and sucrose-reduced diet (SSRD) is a newer, promising diet. Nutrients influence the production of gut hormones, which affect gastrointestinal motility. This study aimed to investigate the changes in copeptin, leptin, PAI-1, C-peptide, and insulin in patients with IBS following a 4-week dietary intervention and to explore whether these hormonal levels correlated with symptom improvements. A total of 142 participants with IBS were randomized to either a 4-week intervention with the SSRD (n = 70) or a low-FODMAP diet (n = 72). Participants completed the study questionnaire, food diary, ROME IV questionnaire, irritable bowel syndrome severity scoring system (IBS-SSS), and visual analog scale for irritable bowel syndrome (VAS-IBS) at baseline and after 4 weeks and 6 months; blood samples were collected at each of these time points. Leptin levels decreased from baseline to 4 weeks in the SSRD group (p = 0.002) but not in the low-FODMAP group (p = 0.153). In the overall study population, leptin (p = 0.001) and PAI-1 (p = 0.019) levels decreased from baseline to 4 weeks. Leptin changes were mainly associated with alterations in carbohydrate intake but not with symptom changes. These findings suggest that the SSRD reduces the levels of leptin in patients with IBS, while PAI-1 levels decrease independently of the dietary intervention, without a corresponding impact on symptoms. Full article
(This article belongs to the Section Molecular Endocrinology and Metabolism)
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19 pages, 490 KiB  
Article
A Starch- and Sucrose-Reduced Diet Has Similar Efficiency as Low FODMAP in IBS—A Randomized Non-Inferiority Study
by Bodil Roth, Mohamed Nseir, Håkan Jeppsson, Mauro D’Amato, Kristina Sundquist and Bodil Ohlsson
Nutrients 2024, 16(17), 3039; https://doi.org/10.3390/nu16173039 - 9 Sep 2024
Cited by 6 | Viewed by 14945
Abstract
A diet with low content of fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is established treatment for irritable bowel syndrome (IBS), with well-documented efficiency. A starch- and sucrose-reduced diet (SSRD) has shown similar promising effects. The primary aim of this randomized, non-inferiority [...] Read more.
A diet with low content of fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is established treatment for irritable bowel syndrome (IBS), with well-documented efficiency. A starch- and sucrose-reduced diet (SSRD) has shown similar promising effects. The primary aim of this randomized, non-inferiority study was to test SSRD against low FODMAP and compare the responder rates (RR = ∆Total IBS-SSS ≥ −50) to a 4-week dietary intervention of either diet. Secondary aims were to estimate responders of ≥100 score and 50% reduction; effects on extraintestinal symptoms; saturation; sugar craving; anthropometric parameters; and blood pressure. 155 IBS patients were randomized to SSRD (n = 77) or low FODMAP (n = 78) for 4 weeks, with a follow-up 5 months later without food restrictions. The questionnaires Rome IV, IBS-severity scoring system (IBS-SSS), and visual analog scale for IBS (VAS-IBS) were completed at baseline and after 2 and 4 weeks and 6 months. Weight, height, waist circumference, and blood pressures were measured. Comparisons were made within the groups and between changes in the two groups. There were no differences between groups at baseline. The responder rate of SSRD was non-inferior compared with low FODMAPs at week 2 (79.2% vs. 73.1%; p = 0.661;95% confidence interval (CI) = −20–7.2) and week 4 (79.2% vs. 78.2%; p = 1.000;95%CI = −14–12). Responder rate was still high when defined stricter. All gastrointestinal and extraintestinal symptoms were equally improved (p < 0.001 in most variables). SSRD rendered greater reductions in weight (p = 0.006), body mass index (BMI) (p = 0.005), and sugar craving (p = 0.05), whereas waist circumference and blood pressure were equally decreased. Weight and BMI were regained at follow-up. In the SSRD group, responders at 6 months still had lowered weight (−0.7 (−2.5–0.1) vs. 0.2 (−0.7–2.2) kg; p = 0.005) and BMI (−0.25 (−0.85–0.03) vs. 0.07 (−0.35–0.77) kg/m2; p = 0.009) compared with baseline in contrast to non-responders. Those who had tested both diets preferred SSRD (p = 0.032). In conclusion, a 4-week SSRD intervention was non-inferior to low FODMAP regarding responder rates of gastrointestinal IBS symptoms. Furthermore, strong reductions of extraintestinal symptoms were found in both groups, whereas reductions in weight, BMI, and sugar craving were most pronounced following SSRD. Full article
(This article belongs to the Section Clinical Nutrition)
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11 pages, 227 KiB  
Article
School Absenteeism Longer Than Two Weeks Is a Red Flag of Somatic Symptom and Related Disorders in Hospitalised Children and Adolescents: A Matched Cohort Study
by Karen Console, Giorgio Cozzi, Giada Caiffa, Sara Romano, Giulia Gortani, Andrea Clarici, Egidio Barbi and Elena Magni
Children 2024, 11(6), 613; https://doi.org/10.3390/children11060613 - 21 May 2024
Cited by 1 | Viewed by 1180
Abstract
Chronic school absenteeism is a common problem in childhood and adolescence, and it is frequently observed in patients with somatic symptom and related disorders (SSRDs). This study aimed to determine whether and to what extent the presence of school absenteeism may be a [...] Read more.
Chronic school absenteeism is a common problem in childhood and adolescence, and it is frequently observed in patients with somatic symptom and related disorders (SSRDs). This study aimed to determine whether and to what extent the presence of school absenteeism may be a risk factor for the diagnosis of SSRDs in hospitalised patients. This matched cohort study included children and adolescents aged between 8 and 17 years, admitted to the paediatric ward of the IRCCS Burlo Garofolo in Trieste from 2021 to 2023, who were divided into two groups, the first including children with at least 15 days of absence from school for medical reasons and the second including children with regular school attendance, matched to the former group by age and sex. We consecutively enrolled 70 patients, 35 in the absentee group and 35 in the control group. In the absentee group, 30/35 (85.7%) patients were diagnosed with an SSRD, while in the control group, 1/35 (2.9%) was diagnosed with an SSRD. The absentee group had a 30-fold higher risk of being diagnosed with SSRDs than the control group (RR = 30 [95% CI = 4.3–208]; p < 0.001). This study shows that in hospitalised children, a history of school absenteeism of more than two weeks is an important risk factor for the diagnosis of SSRDs. Full article
18 pages, 8150 KiB  
Article
Buildings’ Heating and Cooling Load Prediction for Hot Arid Climates: A Novel Intelligent Data-Driven Approach
by Kashif Irshad, Md. Hasan Zahir, Mahaboob Sharief Shaik and Amjad Ali
Buildings 2022, 12(10), 1677; https://doi.org/10.3390/buildings12101677 - 12 Oct 2022
Cited by 14 | Viewed by 2874
Abstract
An important aspect in improving the energy efficiency of buildings is the effective use of building heating and cooling load prediction models. A lot of studies have been undertaken in recent years to anticipate cooling and heating loads. Choosing the most effective input [...] Read more.
An important aspect in improving the energy efficiency of buildings is the effective use of building heating and cooling load prediction models. A lot of studies have been undertaken in recent years to anticipate cooling and heating loads. Choosing the most effective input parameters as well as developing a high-accuracy forecasting model are the most difficult and important aspects of prediction. The goal of this research is to create an intelligent data-driven load forecast model for residential construction heating and cooling load intensities. In this paper, the shuffled shepherd red deer optimization linked self-systematized intelligent fuzzy reasoning-based neural network (SSRD-SsIF-NN) is introduced as a novel intelligent data-driven load prediction method. To test the suggested approaches, a simulated dataset based on the climate of Dhahran, Saudi Arabia will be employed, with building system parameters as input factors and heating and cooling loads as output results for each system. The simulation of this research is executed using MATLAB software. Finally, the theoretical and experimental results demonstrate the efficacy of the presented techniques. In terms of Mean Square Error (MSE), Root Mean Square Error (RMSE), Regression (R) values, Mean Absolute Error (MAE), coefficient of determination (R2), and other metrics, their prediction performance is compared to that of other conventional methods. It shows that the proposed method has achieved the finest performance of load prediction compared with the conventional methods. Full article
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22 pages, 8517 KiB  
Article
Rapid Vehicle Detection in Aerial Images under the Complex Background of Dense Urban Areas
by Shengjie Zhu, Jinghong Liu, Yang Tian, Yujia Zuo and Chenglong Liu
Remote Sens. 2022, 14(9), 2088; https://doi.org/10.3390/rs14092088 - 27 Apr 2022
Cited by 5 | Viewed by 2936
Abstract
Vehicle detection on aerial remote sensing images under the complex background of urban areas has always received great attention in the field of remote sensing; however, the view of remote sensing images usually covers a large area, and the size of the vehicle [...] Read more.
Vehicle detection on aerial remote sensing images under the complex background of urban areas has always received great attention in the field of remote sensing; however, the view of remote sensing images usually covers a large area, and the size of the vehicle is small and the background is complex. Therefore, compared with object detection in the ground view images, vehicle detection in aerial images remains a challenging problem. In this paper, we propose a single-scale rapid convolutional neural network (SSRD-Net). In the proposed framework, we design a global relational (GR) block to enhance the fusion of local and global features; moreover, we adjust the image segmentation method to unify the vehicle size in the input image, thus simplifying the model structure and improving the detection speed. We further introduce an aerial remote sensing image dataset with rotating bounding boxes (RO-ARS), which has complex backgrounds such as snow, clouds, and fog scenes. We also design a data augmentation method to get more images with clouds and fog. Finally, we evaluate the performance of the proposed model on several datasets, and the experimental results show that the recall and precision are improved compared with existing methods. Full article
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19 pages, 1251 KiB  
Article
A Starch- and Sucrose-Reduced Diet in Irritable Bowel Syndrome Leads to Lower Circulating Levels of PAI-1 and Visfatin: A Randomized Controlled Study
by Bodil Roth, Julia Myllyvainio, Mauro D’Amato, Ewa Larsson and Bodil Ohlsson
Nutrients 2022, 14(9), 1688; https://doi.org/10.3390/nu14091688 - 19 Apr 2022
Cited by 5 | Viewed by 3353
Abstract
Irritable bowel syndrome (IBS) is characterized by gastrointestinal symptoms. Overweight and increased risk of metabolic syndromes/diabetes are observed in IBS, conditions associated with plasminogen activator inhibitor-1 (PAI-1) and visfatin. The aim of this study was to measure blood levels of AXIN1, cholecystokinin (CCK), [...] Read more.
Irritable bowel syndrome (IBS) is characterized by gastrointestinal symptoms. Overweight and increased risk of metabolic syndromes/diabetes are observed in IBS, conditions associated with plasminogen activator inhibitor-1 (PAI-1) and visfatin. The aim of this study was to measure blood levels of AXIN1, cholecystokinin (CCK), enkephalin, ghrelin, neuropeptide Y (NPY), PAI-1, and visfatin before and after a 4-week intervention with a starch- and sucrose-reduced diet (SSRD). A total of 105 IBS patients were randomized to either SSRD (n = 80) or ordinary diet (n = 25). Questionnaires were completed, and blood was analyzed for AXIN1 and hormones. AXIN1 (p = 0.001) and active ghrelin levels (p = 0.025) were lower in IBS than in healthy volunteers at baseline, whereas CCK and enkephalin levels were higher (p < 0.001). In the intervention group, total IBS-symptom severity score (IBS-SSS), specific gastrointestinal symptoms, psychological well-being, and the influence of intestinal symptoms on daily life were improved during the study, and weight decreased (p < 0.001 for all), whereas only constipation (p = 0.045) and bloating (p = 0.001) were improved in the control group. PAI-1 levels tended to be decreased in the intervention group (p = 0.066), with a difference in the decrease between groups (p = 0.022). Visfatin levels were decreased in the intervention group (p = 0.007). There were few correlations between hormonal levels and symptoms. Thus, this diet not only improves IBS symptoms but also seems to have a general health-promoting effect. Full article
(This article belongs to the Special Issue Gluten-Free Diet and Gastrointestinal Diseases)
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16 pages, 38498 KiB  
Article
Co-Pyrolysis of Sewage Sludge and Wetland Biomass Waste for Biochar Production: Behaviors of Phosphorus and Heavy Metals
by Ilham Gbouri, Fan Yu, Xutong Wang, Junxia Wang, Xiaoqiang Cui, Yanjun Hu, Beibei Yan and Guanyi Chen
Int. J. Environ. Res. Public Health 2022, 19(5), 2818; https://doi.org/10.3390/ijerph19052818 - 28 Feb 2022
Cited by 31 | Viewed by 4056
Abstract
Large amounts of sewage sludge (SS) and wetland plant wastes are generated in the wastewater treatment system worldwide. The conversion of these solid wastes into biochar through co-pyrolysis could be a promising resource utilization scheme. In this study, biochar was prepared by co-pyrolysis [...] Read more.
Large amounts of sewage sludge (SS) and wetland plant wastes are generated in the wastewater treatment system worldwide. The conversion of these solid wastes into biochar through co-pyrolysis could be a promising resource utilization scheme. In this study, biochar was prepared by co-pyrolysis of SS and reed (Phragmites australis, RD) using a modified muffle furnace device under different temperatures (300, 500, and 700 °C) and with different mixing ratios (25, 50, and 75 wt.% RD). The physicochemical properties of biochar and the transformation behaviors of phosphorus (P) and heavy metals during the co-pyrolysis process were studied. Compared with single SS pyrolysis, the biochar derived from SS-RD co-pyrolysis had lower yield and ash content, higher pH, C content, and aromatic structure. The addition of RD could reduce the total P content of biochar and promote the transformation from non-apatite inorganic phosphorus (NAIP) to apatite phosphorus (AP). In addition, co-pyrolysis also reduced the content and toxicity of heavy metals in biochar. Therefore, co-pyrolysis could be a promising strategy to achieve the simultaneous treatment of SS and RD, as well as the production of value-added biochar. Full article
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17 pages, 1177 KiB  
Article
Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet
by Hans Stenlund, Clara Nilholm, Elin Chorell, Bodil Roth, Mauro D’Amato and Bodil Ohlsson
Metabolites 2021, 11(7), 440; https://doi.org/10.3390/metabo11070440 - 4 Jul 2021
Cited by 12 | Viewed by 3699
Abstract
A 4-week dietary intervention with a starch- and sucrose-restricted diet (SSRD) was conducted in patients with irritable bowel syndrome (IBS) to examine the metabolic profile in relation to nutrient intake and gastrointestinal symptoms. IBS patients were randomized to SSRD intervention (n = [...] Read more.
A 4-week dietary intervention with a starch- and sucrose-restricted diet (SSRD) was conducted in patients with irritable bowel syndrome (IBS) to examine the metabolic profile in relation to nutrient intake and gastrointestinal symptoms. IBS patients were randomized to SSRD intervention (n = 69) or control continuing with their ordinary food habits (n = 22). Food intake was registered and the questionnaires IBS-symptoms severity scale (IBS-SSS) and visual analog scale for IBS (VAS-IBS) were completed. Metabolomics untargeted analysis was performed by gas chromatography mass spectrometry (GC-MS) and liquid chromatography mass spectrometry (LC-MS) in positive and negative ionization modes. SSRD led to marked changes in circulating metabolite concentrations at the group level, most prominent for reduced starch intake and increased polyunsaturated fat, with small changes in the control group. On an individual level, the correlations were weak. The marked reduction in gastrointestinal symptoms did not correlate with the metabolic changes. SSRD was observed by clear metabolic effects mainly related to linoleic acid metabolism, fatty acid biosynthesis, and beta-oxidation. Full article
(This article belongs to the Section Nutrition and Metabolism)
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19 pages, 1256 KiB  
Article
Assessment of a 4-Week Starch- and Sucrose-Reduced Diet and Its Effects on Gastrointestinal Symptoms and Inflammatory Parameters among Patients with Irritable Bowel Syndrome
by Clara Nilholm, Ewa Larsson, Emily Sonestedt, Bodil Roth and Bodil Ohlsson
Nutrients 2021, 13(2), 416; https://doi.org/10.3390/nu13020416 - 28 Jan 2021
Cited by 34 | Viewed by 6114
Abstract
Dietary advice constitutes a treatment strategy for irritable bowel syndrome (IBS). We aimed to examine the effect of a starch- and sucrose-reduced diet (SSRD) on gastrointestinal symptoms in IBS patients, in relation to dietary intake and systemic inflammatory parameters. IBS patients (n [...] Read more.
Dietary advice constitutes a treatment strategy for irritable bowel syndrome (IBS). We aimed to examine the effect of a starch- and sucrose-reduced diet (SSRD) on gastrointestinal symptoms in IBS patients, in relation to dietary intake and systemic inflammatory parameters. IBS patients (n = 105) were randomized to a 4-week SSRD intervention (n = 80) receiving written and verbal dietary advice focused on starch and sucrose reduction and increased intake of protein, fat and dairy, or control group (n = 25; habitual diet). At baseline and 4 weeks, blood was sampled, and participants filled out IBS-SSS, VAS-IBS, and Rome IV questionnaires and dietary registrations. C-reactive protein and cytokines TNF-α, IFN-γ, IL-6, IL-8, IL-10, and IL-18 were analyzed from plasma. At 4 weeks, the intervention group displayed lower total IBS-SSS, ‘abdominal pain’, ‘bloating/flatulence’ and ‘intestinal symptoms´ influence on daily life’ scores (p ≤ 0.001 for all) compared to controls, and a 74%, responder rate (RR = ΔTotal IBS-SSS ≥ −50; RRcontrols = 24%). Median values of sucrose (5.4 vs. 20 g), disaccharides (16 vs. 28 g), starch (22 vs. 82 g) and carbohydrates (88 vs. 182 g) were lower for the intervention group compared to controls (p ≤ 0.002 for all), and energy percentages (E%) of protein (21 vs. 17 E%, p = 0.006) and fat (47 vs. 38 E%, p = 0.002) were higher. Sugar-, starch- and carbohydrate-reductions correlated weakly-moderately with total IBS-SSS decrease for all participants. Inflammatory parameters were unaffected. IBS patients display high compliance to the SSRD, with improved gastrointestinal symptoms but unaltered inflammatory parameters. In conclusion, the SSRD constitutes a promising dietary treatment for IBS, but needs to be further researched and compared to established dietary treatments before it could be used in a clinical setting. Full article
(This article belongs to the Section Clinical Nutrition)
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15 pages, 1055 KiB  
Article
A Dietary Intervention with Reduction of Starch and Sucrose Leads to Reduced Gastrointestinal and Extra-Intestinal Symptoms in IBS Patients
by Clara Nilholm, Bodil Roth and Bodil Ohlsson
Nutrients 2019, 11(7), 1662; https://doi.org/10.3390/nu11071662 - 20 Jul 2019
Cited by 32 | Viewed by 8392
Abstract
Patients with irritable bowel syndrome (IBS) exhibit low-grade inflammation and increased gut permeability. Dietary sugar has been shown to contribute to low-grade inflammation and increased gut permeability, and to correlate with gastrointestinal (GI) symptoms. The aim of the present study was to examine [...] Read more.
Patients with irritable bowel syndrome (IBS) exhibit low-grade inflammation and increased gut permeability. Dietary sugar has been shown to contribute to low-grade inflammation and increased gut permeability, and to correlate with gastrointestinal (GI) symptoms. The aim of the present study was to examine the effect of a starch- and sucrose-reduced diet (SSRD) on gastrointestinal (GI) and extra-intestinal symptoms in IBS. One hundred and five IBS patients (82 women, 46.06 ± 13.11 years), with irritable bowel syndrome-symptom severity scale (IBS-SSS) > 175, were randomized to SSRD for 4 weeks or continued ordinary eating habits. The visual analog scale for irritable bowel syndrome (VAS-IBS), IBS-SSS, and 4-day food diaries were collected at baseline and after 2 and 4 weeks. After the intervention, one-third of the patients did not fulfill the criteria for IBS/functional gastrointestinal disorder. Half of the participants changed from moderate/severe disease to no/mild disease according to IBS-SSS. Comparisons between the groups showed decreased weight and sweet cravings, and parallel decreases in total IBS-SSS and extra-intestinal IBS-SSS scores, in the intervention group compared to controls (p < 0.001 for all). When calculating separate extra-intestinal symptoms, belching (p = 0.001), muscle/joint pain (p = 0.029), urinary urgency (p = 0.017), and tiredness (p = 0.011) were decreased after introduction of SSRD compared to controls. In conclusion, SSRD improves both GI and extra-intestinal symptoms in IBS. Full article
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17 pages, 564 KiB  
Article
Irregular Dietary Habits with a High Intake of Cereals and Sweets Are Associated with More Severe Gastrointestinal Symptoms in IBS Patients
by Clara Nilholm, Ewa Larsson, Bodil Roth, Rita Gustafsson and Bodil Ohlsson
Nutrients 2019, 11(6), 1279; https://doi.org/10.3390/nu11061279 - 5 Jun 2019
Cited by 51 | Viewed by 7213
Abstract
Dietary advice constitutes one of the first choices of treatment for irritable bowel syndrome (IBS). We have recognized an increased prevalence of sucrase-isomaltase (SI) gene variants in IBS patients, possibly rendering starch- and sucrose-intolerance. The aims were to examine participants’ dietary habits at [...] Read more.
Dietary advice constitutes one of the first choices of treatment for irritable bowel syndrome (IBS). We have recognized an increased prevalence of sucrase-isomaltase (SI) gene variants in IBS patients, possibly rendering starch- and sucrose-intolerance. The aims were to examine participants’ dietary habits at baseline, to correlate habits with gastrointestinal (GI) symptoms and blood levels of minerals and vitamins, and to examine the effect of a starch- and sucrose-reduced diet (SSRD) on GI symptoms. In the study 105 IBS patients (82 women, 46.06 ± 13.11 years), irritable bowel syndrome-symptom severity scale (IBS-SSS)>175, were randomized to SSRD for 2 weeks or continued ordinary eating habits. Blood samples, visual analog scale for irritable bowel syndrome (VAS-IBS), IBS-SSS, and 4-day food diaries were collected at baseline and after 2 weeks. Patients with irregular dietary habits exhibited higher IBS-SSS than patients with regular habits (p = 0.029). Women already on a diet had lower ferritin levels than others (p = 0.029). The intervention led to 66.3% of patients being responders, with differences in the change of IBS-SSS (p < 0.001), abdominal pain (p = 0.001), diarrhea (p = 0.002), bloating and flatulence (p = 0.005), psychological well-being (p = 0.048), and intestinal symptoms’ influence on daily life (p < 0.001), compared to controls. Decreased intake of cereals and sweets/soft drinks correlated with decreased scores. Full article
(This article belongs to the Special Issue Nutritional Management of Gastrointestinal Diseases and Disorders)
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