Search Results (18)

As the primary electronic payload of laser interferometry system for space gravitational wave detection, the core function of the phasemeter is ultra-high precision phase measurement. According to the principle of laser heterodyne interferometry and the requirement of 1 pm ranging accuracy of the phasemeter, the phase measurement noise should reach 2π μrad/Hz^1/2@(0.1 mHz–1 Hz). The heterodyne interference signal first passes through the quadrant photoelectric detector (QPD) to achieve photoelectric conversion, then passes through the analog-to-digital converter (ADC) to achieve analog and digital conversion, and finally passes through the digital phase-locked loop (DPLL) for phase locking. The sampling timing jitter of the heterodyne interference signal caused by the ADC is the main noise affecting the phase measurement performance and must be suppressed. This paper proposes a sampling timing jitter noise suppression system (STJNSS), which can set system parameters for high-frequency signals used for inter-satellite clock noise transmission, the system clock of the phasemeter, and the pilot frequency for suppressing ADC sampling timing jitter noise, meeting the needs of the current major space gravitational wave detection plans. The experimental results after the integration of SJNSS and the phase meter show that the phase measurement noise of the heterodyne interferometer signal reaches 2π μrad/Hz^1/2@(0.1 mHz–1 Hz), which meets the requirements of space gravitational wave missions. Full article

On-chip optical accelerometers can be a promising alternative to capacitive, piezo-resistive, and piezo-electric accelerometers in some applications due to their immunity to electromagnetic interference and high sensitivity, which allow for robust operation in electromagnetically noisy environments. This paper focuses on the characterization of an easy-to-fabricate tri-axial fiber-free optical MEMS accelerometer, which employs a simple assembly consisting of a light emitting diode (LED), a quadrant photodetector (QPD), and a suspended proof mass, measuring acceleration through light power modulation. This configuration enables simple readout circuitry without the need for complex digital signal processing (DSP). Performance modeling was conducted to simulate the LED’s irradiance profile and its interaction with the proof mass and QPD. Additionally, experimental tests were performed to measure the device’s mechanical sensitivity and validate the mechanical model. Lateral mechanical sensitivity is obtained with acceptable discrepancy from that obtained from FEA simulations. This work consolidates the performance of the design adapted and demonstrates the accelerometer’s feasibility for practical applications. Full article

Background: Non-specific low back pain is the leading cause of years lived with disability worldwide. The present study investigates non-specific low back pain, pain perceptions and disability due to pain among Brazilian Jiu Jitsu, Muay Thai and Boxing athletes. Methods: The study included 90 amateur athletes (aged 18–45 years; M = 28.97, SD = 5.88). The athletes completed the valid and reliable Pain Beliefs Perceptions Inventory (PBPI), the Quebec Pain Disability Scale (QPDS) and the Short-Form McGill Pain Questionnaire (SF-MPQ) which includes the Visual Analogue Scale (10 cm VAS 0–10 rating system) and the Present Pain Intensity index (PPI). Results: The results revealed that the majority of athletes rated their pain as low (SF-MPQ: M = 12.34, SD = 8.91; VAS: M = 1.65, SD = 1.82; PPI: M = 2.10, SD = 1.08) with low disability due to pain (QPDS: M = 18.98, SD = 22.71). Also, the majority of athletes disagreed that their pain was mysterious or persistent with high duration (PBPI: M = 1.43, SD = 2.23). Between the three martial arts, Brazilian Jiu Jitsu athletes showed statistically significantly (a) higher emotional and sensational pain intensity (x²(2) = 15.73; p < 0.001; x²(2) = 19.34; p < 0.001), (b) higher disability due to pain (x²(2)= 25.30; p < 0.001) and (c) more mysterious, more persistent pain with more duration (x²(2)= 9.32; p < 0.05) than Muay Thai and Boxing athletes. Also, a few correlations were found between age and pain perception only in Brazilian Jiu Jitsu and Boxing martial arts athletes. Conclusions: Further research is required to elucidate the biomechanical and psychological factors contributing to these differences between martial arts athletes. Full article

Red palm weevil, Rhynchophorus ferrugineus (Olivier), is a palm tree insect pest that causes significant damage in the many countries from the Indian sub-continent and southeast Asia into date palm-growing countries of Africa, the Middle East, and the Mediterranean Basin. This study is aimed at determining the role of a C-type lectin, RfCTL27, in the immune defense of RPW larvae. RfCTL27 is a secreted protein that possesses a QPD motif, being integral for the discrimination of Gram-negative bacteria. The abundance of RfCTL27 transcripts in the gut and fat body was significantly higher than that in other tissues. Six hours after injection of Escherichia coli, the expression level of RfCTL27 in the gut of RPW larvae was significantly elevated compared with other groups. At 12 h after injection of E. coli, the expression of RfCTL27 in fat body was dramatically induced in contrast with other treatments. More interestingly, the ability of RPW larvae to clear the pathogenic bacteria in the body cavity and gut was markedly impaired by the silencing of RfCTL27. Additionally, the expression levels of two antimicrobial peptide genes, RfCecropin in the gut and RfDefensin in fat body of RPW larvae, were significantly decreased. Taken together, these data suggested that RfCTL27 can recognize the Gram-negative bacterium and activate the expression of antimicrobial peptides to remove the invaded bacterial pathogens. This study provides a new scientific basis for improving the control efficiency of pathogenic microorganisms against red palm weevils in production practice. Full article

This study presents a systematic design of an optimized drive signal control system for 2.5 GHz Doherty power amplifiers (DPAs). The designed system enables the analysis of the independent control of the amplitude and phase for the signals between the main and peak amplifiers of the DPA. The independent control of the signal is achieved by incorporating a variable attenuator (VA) and a variable phase shifter (VPS) in each of the two parallel paths of the DPA. This integration allows for driving varying power levels with an arbitrary phase difference between the individual parallel PAs for reduced control complexity and power consumption. The specific VA (Qorvo QPC6614) and VPS (Qorvo QPC2108) components are used for the test system to provide an amplitude attenuation range from 0.5 dB to 31.5 dB and a phase range from $0^{\circ }$ to ${360}^{\circ }$ at the intended operating frequency of 2.5 GHz, offering the benefit of characterizing the behavior of PAs for an extensive range of drive signals to optimize the output performance, such as PAE or the ACLR. For experimental validation, the designed drive signal control system is integrated with GaN PAs (Qorvo QPD0005—DUT) with a $P_{1dB}$ of 37.7 dBm. Each PA is preceded by a drive amplifier with a gain of 17.8 dB to boost the power fed into the PA. In this manuscript, we analyzed and compared the PAE of the DPA and parallel-connected PA for diverse input signals generated using a designed optimized control system. Full article

Background: As a subjective sensation, pain is difficult to evaluate objectively. The assessment of pain degree is largely dependent on subjective methods such as the numeric rating scale (NRS). The PainVision^TM system has recently been introduced as an objective pain degree measurement tool. The purpose of this study was to analyze correlations between the NRS and the current perception threshold (CPT), pain equivalent current (PEC), and quantified pain degree (QPD). Methods: Medical records of 398 subjects who visited the pain clinic in a university hospital from March 2017 to February 2019 were retrospectively reviewed. To evaluate the pain degree, NRS, CPT, PEC, and QPD were measured. Subjects were categorized into two groups: the Pain group (n = 355) and the No-pain group (n = 43). Results: The NRS showed a negative correlation with CPT (R = −0.10, p = 0.054) and a positive correlation with QPD (R = 0.13, p = 0.008). Among various diseases, only spinal disease patients showed a negative correlation between CPT and NRS (R = −0.22, p = 0.003). Additionally, there were significant differences in CPT and QPD between the Pain and No-pain groups (p = 0.005 and p = 0.002, respectively). Conclusions: CPT and QPD measured using the PainVision^TM system could be used to estimate pain intensity and the presence of pain. These parameters would be considered useful for predicting pain itself and its intensity. Full article

An absolute-type four-degree-of-freedom (four-DOF) grating encoder that can simultaneously measure the three-axis pose (θx, θy, θz) and one-axis out-of-plane position (Z) of an object with high accuracy is demonstrated for the first time in this research. This grating encoder is composed of a stationary reading head and a movable grating reflector. A light beam from the reading head is projected onto the grating, and three diffracted beams (0th-, +1st-, and −1st-order) are generated, collimated, and received by three separate quadrant photodetectors (QPDs). The information of θx, θy, θz, and Z is coded into spot positions of these three diffracted beams on the QPDs. Thus, the modeling and decoupling algorithms were investigated, and an independent calculation of these four-DOF absolute positions was theoretically guaranteed. A prototype was then designed, constructed, and evaluated. Experimental results verified that the proposed grating encoder could achieve the absolute measurement of four-DOF θx, θy, θz, and Z with an accuracy of sub-arcseconds and sub-micrometers. To the best of our knowledge, the proposed encoder in this research is the first one to achieve absolute simultaneous measurements of four-DOF position and pose with a large measurement range. The success of this new grating encoder can benefit various multi-DOF positioning applications, especially for large-scale synthetic aperture optics (SAO), including stitching off-axis parabolic mirrors and pulse compression grating. Full article

Colloidal quantum dots (CQDs) have a unique advantage in realizing near-infrared (NIR) photodetection since their optical properties are readily tuned by the particle size, but CQD-based photodetectors (QPDs) presently show a high dark current density (J_d) and insufficient dynamic characteristics. To overcome these two problems, we synthesized and introduced two types of conjugated polymers (CPs) by replacing the p-type CQD layer in the QPDs. The low dielectric constant and insulating properties of CPs under dark conditions effectively suppressed the J_d in the QPDs. In addition, the energy-level alignment and high-hole mobility of the CPs facilitated hole transport. Therefore, both the responsivity and specific detectivity were highly enhanced in the CP-based QPDs. Notably, the dynamic characteristics of the QPDs, such as the −3 dB cut-off frequency and rising/falling response times, were significantly improved in the CP-based QPDs owing to the sizable molecular ordering and fast hole transport of the CP in the film state as well as the low trap density, well-aligned energy levels, and good interfacial contact in the CP-based devices. Full article

Free space optical (FSO) communication can support various unmanned aerial vehicles’ (UAVs) applications that require large capacity data transmission. In order to perform FSO communication between two terminals, it is essential to employ a pointing, acquisition, and tracking (PAT) system with an efficient and optimal performance. We report on the development of a common optical-path-based FSO communication system, tailored for applications in UAVs. The proposed system is equipped with a quadrant photodiode (QPD)-based PAT system without an additional beacon beam subsystem. The presented approach reduced the structural complexity and improved the tracking efficiency for the same size, weight, and power (SWaP). To achieve a robust FSO link in a dynamic UAV environment, the observability and controllability were obtained based on the linearized control according to the incident beam size on the QPD, which was verified by optical simulation and experiments. As a result, the QPD-based PAT system for implementing FSO links demonstrated an up to 4.25 times faster tracking performance. Moreover, the FSO link experimentally confirmed the 1.25 Gbps full-duplex error-free communication at a 50 m distance. Full article

The quadrature angular diversity aperture (QADA) receiver, consisting of a quadrant photodiode (QPD) and an aperture placed above the QPD, has been investigated for pose estimation for visible light systems. Current work on pose estimation for the QADA receiver uses classical camera sensor algorithms well known in computer vision. To this end, however, the light spot center first has to be obtained based on the RSS. However, this is less straightforward than for camera sensors, as in contrast to such sensors where the relationships are linear, the RSS output from the QADA is a non-linear function of the light spot position. When applying closed form solutions or iterative methods for cameras on a QADA, the non-linearity will degrade their performance. Furthermore, since in practice the aperture is not always perfectly aligned with the QPD, a procedure to calibrate the receiver is needed. Current work on calibration requires additional sophisticated equipment to measure the pose during calibration, which increases the difficulty of implementation. In this paper, we target the above problems for pose estimation and calibration of the QADA receiver. To this end, we first study the effect of the strategy of differencing and normalization on the probability density function (PDF), a commonly applied strategy for the QPD’s robustness against RSS variation, and it is shown that the applied strategy results in a complex PDF, which makes an effective and efficient estimation hard to achieve. Therefore, we derive an approximated PDF in a simple closed-form, based on which the calibration and the pose estimation algorithms using the least squares principle are proposed. The proposed calibration does not require any information about the pose of the receiver and is robust to variation of the received power and imperfect knowledge of the radiation pattern of the LED, making it easy to implement. We also derive the corresponding Cramér-Rao lower bound on the misalignment to benchmark the performance of the misalignment and to serve as an indicator to determine the required signal-to-noise ratio (SNR) or number of LEDs to obtain a desired accuracy. The calibration and pose estimation are evaluated by means of a Monte Carlo simulation. Computer simulations show that this theoretical bound is close to the RMSE of the proposed estimator and that the proposed pose estimator outperforms the PnP algorithm. Full article

Absorbed energy in excess of that used by photosynthesis induces photoinhibition, which is common in water deficit conditions, resulting in reductions in stomatal conductance. In grapevines, controlled water deficit is a common field practice, but little is known about the impact of a given water shortage on the energy transduction processes at the leaf level in relation to contrasting stomatal sensitivities to drought. Here, we assessed the effect of a nearly similar water deficit condition on four grapevine varieties: Cabernet Sauvignon (CS) and Sauvignon Blanc (SB), which are stomatal sensitive, and Chardonnay (CH) and Carménère (CM), which are less stomatal sensitive, grown in 20 L pots outdoors. Plants were maintained to nearly 94% of field capacity (WW) and 83% field capacity (WD). We have assessed plant water status, photosynthesis (A_N), photorespiration, A_N vs. PAR, AC_i curves, photochemical (qP) and non-photochemical (qN) fluorescence quenching vs. PAR, the photoprotective effectiveness of NPQ (qPd) and light interception by leaves. Photorespiration is important under WD, but to a different extent between varieties. This is related to stomatal sensitivity, maintaining a safe proportion of PSII reaction centres in an open state. Additionally, the capacity for carboxylation is affected by WD, but to a greater extent in more sensitive varieties. As for qN, in WD it saturates at 750 μmol PAR m⁻²s⁻¹, irrespective of the variety, which coincides with PAR, from which qN photoprotective effectiveness declines, and qP is reduced to risky thresholds. Additionally, that same PAR intensity is intercepted by WD leaves from highly stomatal-sensitive varieties, likely due to a modification of the leaf angle in those plants. Pigments associated with qN, as well as chlorophylls, do not seem to be a relevant physiological target for acclimation. Full article

TmC4-47.2 is a toxin with myotoxic activity found in the venom of Thalassophryne maculosa, a venomous fish commonly found in Latin America whose envenomation produces an injury characterized by delayed neutrophil migration, production of major pro-inflammatory cytokines, and necrosis at the wound site, as well as a specific systemic immune response. However, there are few studies on the protein structure and functions associated with it. Here, the toxin was identified from the crude venom by chromatography and protein purification systems. TmC4-47.2 shows high homology with the Nattectin from Thalassophryne nattereri venom, with 6 cysteines and QPD domain for binding to galactose. We confirm its hemagglutinating and microbicide abilities independent of carbohydrate binding, supporting its classification as a nattectin-like lectin. After performing the characterization of TmC4-47.2, we verified its ability to induce an increase in the rolling and adherence of leukocytes in cremaster post-capillary venules dependent on the α5β1 integrin. Finally, we could observe the inflammatory activity of TmC4-47.2 through the production of IL-6 and eotaxin in the peritoneal cavity with sustained recruitment of eosinophils and neutrophils up to 24 h. Together, our study characterized a nattectin-like protein from T. maculosa, pointing to its role as a molecule involved in the carbohydrate-independent agglutination response and modulation of eosinophilic and neutrophilic inflammation. Full article

An electromagnetic immune Free Space Optical Communication (FSOC) system for an Unmanned Aerial Vehicle (UAV) command and control link is introduced in this paper. The system uses the scheme of omnidirectional receiving and ground scanning transmitting. It has a strong anti-turbulence ability by using a large area detector and short-focus lens. The design of omnidirectional communication improves the ability of anti-vibration and link establishment. Pure static reception has no momentum effect on the platform. The receiver is miniaturized under no use of a gimbal mirror system, beacon camera system, Four-Quadrant Photodetector (QPD) and multi-level lens system. The system can realize omnidirectional reception and the communication probability in 1 s is greater than 99.99%. This design strengthens the ability of the FSOC system, so it can be applied in the UAV command and control, the satellite submarine communication and other occasions where the size of the platform is restricted. Full article

A C-type lectin (PtCLec2) from Portunus trituberculatus was identified for characterization of its role in defense and innate immunity. PtCLec2 contains a single carbohydrate-recognition domain (CRD) with a conserved QPD motif, which was predicted to have galactose specificity. The mRNA expression of PtCLec2 was predominantly detected in intestine and increased rapidly and significantly upon pathogen challenge. The recombinant PtCLec2 (rPtCLec2) could bind various microorganisms and PAMPs with weak binding ability to yeast and PGN. It agglutinated the tested Gram-negative bacteria (Vibrio alginolyticus and Pseudomonas aeruginosa), Gram-positive bacteria (Staphylococcus aureus and Micrococcus luteus), and rabbit erythrocytes in the presence of exogenous Ca²⁺, and these agglutination activities were suppressed by LPS, d-galactose, and d-mannose. Further, rPtCLec2 enhanced phagocytosis and clearance of V. alginolyticus, and displayed inhibitory activities against the tested bacteria. Knockdown of PtCLec2 decreased the transcription of two phagocytosis genes (PtArp and PtMyosin), three prophenoloxidase (proPO) system-related genes (PtPPAF, PtcSP1, and PtproPO), six antimicrobial peptides (AMPs) (PtALF4-7, PtCrustin1, and PtCrustin3), and PtRelish but upregulated the expression levels of PtJNK, PtPelle, and PtTLR. These results collectively indicate that PtCLec2 might perform its immune recognition function via binding and agglutination, and mediate pathogen elimination via regulating hemocyte phagocytosis, AMP synthesis, and proPO activation. Full article

Low-frequency vibration is a harmful factor that affects the accuracy of micro/nano-measuring machines. Low-frequency vibration cannot be completely eliminated by passive control methods, such as the use of air-floating platforms. Therefore, low-frequency vibrations must be measured before being actively suppressed. In this study, the design of a low-cost high-sensitivity optical accelerometer is proposed. This optical accelerometer mainly comprises three components: a seismic mass, a leaf spring, and a sensing component based on a four-quadrant photodetector (QPD). When a vibration is detected, the seismic mass moves up and down due to the effect of inertia, and the leaf spring exhibits a corresponding elastic deformation, which is amplified by using an optical lever and measured by the QPD. Then, the acceleration can be calculated. The resonant frequencies and elastic coefficients of various seismic structures are simulated to attain the optimal detection of low-frequency, low-amplitude vibration. The accelerometer is calibrated using a homemade vibration calibration system, and the calibration experimental results demonstrate that the sensitivity of the optical accelerometer is 1.74 V (m·s⁻²)⁻¹, the measurement range of the accelerometer is 0.003–7.29 m·s⁻², and the operating frequencies range of 0.4–12 Hz. The standard deviation from ten measurements is under 7.9 × 10⁻⁴ m·s⁻². The efficacy of the optical accelerometer in measuring low-frequency, low-amplitude dynamic responses is verified. Full article