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20 Results Found

  • Article
  • Open Access
7 Citations
8,363 Views
11 Pages

Rhodotorula Mucilaginosa, a Quorum Quenching Yeast Exhibiting Lactonase Activity Isolated from a Tropical Shoreline

  • Norshazliza Ab Ghani,
  • Joanita Sulaiman,
  • Zahidah Ismail,
  • Xin-Yue Chan,
  • Wai-Fong Yin and
  • Kok-Gan Chan

9 April 2014

Two microbial isolates from a Malaysian shoreline were found to be capable of degrading N-acylhomoserine lactones. Both Matrix Assisted Laser Desorption Ionization-Time of Flight-Mass Spectrometry and 18S rDNA phylogenetic analyses confirmed that the...

  • Article
  • Open Access
13 Citations
6,779 Views
10 Pages

Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries

  • Share Yuan Goh,
  • Wen-Si Tan,
  • Saad Ahmed Khan,
  • Hooi Pin Chew,
  • Noor Hayaty Abu Kasim,
  • Wai-Fong Yin and
  • Kok-Gan Chan

21 May 2014

Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches. The oral cavity could be a potential area for the presence of QS b...

  • Article
  • Open Access
13 Citations
7,984 Views
11 Pages

Quorum Sensing Activity of Serratia fonticola Strain RB-25 Isolated from an Ex-landfill Site

  • Robson Ee,
  • Yan-Lue Lim,
  • Kok-Keng Tee,
  • Wai-Fong Yin and
  • Kok-Gan Chan

12 March 2014

Quorum sensing is a unique bacterial communication system which permits bacteria to synchronize their behaviour in accordance with the population density. The operation of this communication network involves the use of diffusible autoinducer molecule...

  • Article
  • Open Access
9 Citations
7,238 Views
10 Pages

Characterisation of a Marine Bacterium Vibrio Brasiliensis T33 Producing N-acyl Homoserine Lactone Quorum Sensing Molecules

  • Wen-Si Tan,
  • Nina Yusrina Muhamad Yunos,
  • Pui-Wan Tan,
  • Nur Izzati Mohamad,
  • Tan-Guan-Sheng Adrian,
  • Wai-Fong Yin and
  • Kok-Gan Chan

8 July 2014

N-acylhomoserine lactones (AHL) plays roles as signal molecules in quorum sensing (QS) in most Gram-negative bacteria. QS regulates various physiological activities in relation with population density and concentration of signal molecules. With the...

  • Article
  • Open Access
2 Citations
7,086 Views
12 Pages

Detection of Quorum Sensing Activity in the Multidrug-Resistant Clinical Isolate Pseudomonas aeruginosa Strain GB11

  • Huey Jia Cheng,
  • Robson Ee,
  • Yuet Meng Cheong,
  • Wen-Si Tan,
  • Wai-Fong Yin and
  • Kok-Gan Chan

11 July 2014

A multidrug-resistant clinical bacteria strain GB11 was isolated from a wound swab on the leg of a patient. Identity of stain GB11 as Pseudomonas aeruginosa was validated by using matrix-assisted laser desorption/ionization-time-of-flight mass spectr...

  • Article
  • Open Access
25 Citations
8,746 Views
15 Pages

22 April 2014

Quorum sensing is a well-studied cell-to-cell communication method that involves a cell-density dependent regulation of genes expression mediated by signalling molecules. In this study, a bacterium isolated from a plant material compost pile was foun...

  • Article
  • Open Access
48 Citations
11,123 Views
11 Pages

Quorum Sensing Activity of Enterobacter asburiae Isolated from Lettuce Leaves

  • Yin Yin Lau,
  • Joanita Sulaiman,
  • Jian Woon Chen,
  • Wai-Fong Yin and
  • Kok-Gan Chan

22 October 2013

Bacterial communication or quorum sensing (QS) is achieved via sensing of QS signaling molecules consisting of oligopeptides in Gram-positive bacteria and N-acyl homoserine lactones (AHL) in most Gram-negative bacteria. In this study, Enterobacteriac...

  • Article
  • Open Access
39 Citations
7,341 Views
14 Pages

13 July 2016

One quorum sensing strain was isolated from spoiled turbot. The species was determined by 16S rRNA gene analysis and classical tests, named Aeromonas sobria AS7. Quorum-sensing (QS) signals (N-acyl homoserine lactones (AHLs)) were detected by report...

  • Article
  • Open Access
11 Citations
6,425 Views
10 Pages

Labrenzia sp. BM1: A Quorum Quenching Bacterium That Degrades N-acyl Homoserine Lactones via Lactonase Activity

  • Norshazliza Ab Ghani,
  • Siti Nur Maisarah Norizan,
  • Xin Yue Chan,
  • Wai-Fong Yin and
  • Kok-Gan Chan

3 July 2014

We report the degradation of quorum sensing N-acylhomoserine lactone molecules by a bacterium isolated from a Malaysian marine water sample. MALDI-TOF and phylogenetic analysis indicated this isolate BM1 clustered closely to Labrenzia sp. The quorum...

  • Article
  • Open Access
15 Citations
7,448 Views
9 Pages

Characterization of N-Acylhomoserine Lactones Produced by Bacteria Isolated from Industrial Cooling Water Systems

  • Noriya Okutsu,
  • Tomohiro Morohoshi,
  • Xiaonan Xie,
  • Norihiro Kato and
  • Tsukasa Ikeda

30 December 2015

The cooling water systems are used to remove heat generated in the various industries. Biofouling of the cooling water systems causes blocking of condenser pipes and the heat exchanger tubes. In many Gram-negative bacteria, N-acylhomoserine lactone (...

  • Article
  • Open Access
38 Citations
7,252 Views
25 Pages

Quorum Quenching Properties and Probiotic Potentials of Intestinal Associated Bacteria in Asian Sea Bass Lates calcarifer

  • Reza Ghanei-Motlagh,
  • Takavar Mohammadian,
  • Darioush Gharibi,
  • Simon Menanteau-Ledouble,
  • Esmaeil Mahmoudi,
  • Mohammad Khosravi,
  • Mojtaba Zarea and
  • Mansour El-Matbouli

26 December 2019

Quorum quenching (QQ), the enzymatic degradation of N-acyl homoserine lactones (AHLs), has been suggested as a promising strategy to control bacterial diseases. In this study, 10 AHL-degrading bacteria isolated from the intestine of barramundi were i...

  • Article
  • Open Access
30 Citations
4,436 Views
17 Pages

Quorum Quenching in a Novel Acinetobacter sp. XN-10 Bacterial Strain against Pectobacterium carotovorum subsp. carotovorum

  • Wenping Zhang,
  • Qingqing Luo,
  • Yiyin Zhang,
  • Xinghui Fan,
  • Tian Ye,
  • Sandhya Mishra,
  • Pankaj Bhatt,
  • Lianhui Zhang and
  • Shaohua Chen

Quorum sensing (QS) is a cell density-dependent mechanism that regulates the expression of specific genes in microbial cells. Quorum quenching (QQ) is a promising strategy for attenuating pathogenicity by interfering with the QS system of pathogens....

  • Article
  • Open Access
41 Citations
6,896 Views
11 Pages

Characteristics of N-Acylhomoserine Lactones Produced by Hafnia alvei H4 Isolated from Spoiled Instant Sea Cucumber

  • Hong-Man Hou,
  • Yao-Lei Zhu,
  • Jia-Ying Wang,
  • Feng Jiang,
  • Wen-Yan Qu,
  • Gong-Liang Zhang and
  • Hong-Shun Hao

5 April 2017

This study aimed to identify N-acylhomoserine lactone (AHL) produced by Hafnia alvei H4, which was isolated from spoiled instant sea cucumber, and to investigate the effect of AHLs on biofilm formation. Two biosensor strains, Chromobacterium violaceu...

  • Article
  • Open Access
15 Citations
7,064 Views
10 Pages

Short Chain N-Acylhomoserine Lactone Production by Clinical Multidrug Resistant Klebsiella pneumoniae Strain CSG20

  • Yun Fong Ngeow,
  • Huey Jia Cheng,
  • Jian Woon Chen,
  • Wai-Fong Yin and
  • Kok-Gan Chan

7 November 2013

Klebsiella pneumoniae is one of the most common Gram-negative bacterial pathogens in clinical practice. It is associated with a wide range of disorders, ranging from superficial skin and soft tissue infections to potentially fatal sepsis in the lungs...

  • Article
  • Open Access
6 Citations
7,084 Views
8 Pages

Discovery of Pantoea rodasii Strain ND03 that Produces N-(3-Oxo-hexanoyl)-L-homoserine Lactone

  • Nina Yusrina Muhamad Yunos,
  • Wen-Si Tan,
  • Nur Izzati Mohamad,
  • Pui-Wan Tan,
  • Tan-Guan-Sheng Adrian,
  • Wai-Fong Yin and
  • Kok-Gan Chan

23 May 2014

Proteobacteria use quorum sensing to regulate target gene expression in response to population density. Quorum sensing (QS) is achieved via so-called signalling molecules and the best-studied QS signalling system uses N-acyl homoserine lactones (AHLs...

  • Article
  • Open Access
2 Citations
1,634 Views
19 Pages

Enhanced Anaerobic Digestion Performance Through Acyl Homoserine Lactone-Mediated Quorum Sensing and Supplemental Voltage Regulation

  • Jie Zhou,
  • Mingxuan Xu,
  • Diwen Cao,
  • Shuhuan Li,
  • Xiaorui Yang,
  • Weiliang Dong,
  • Honghua Jia and
  • Xiayuan Wu

Traditional anaerobic digestion (AD) technology continues to have severe limitations in terms of complicated substrate degradation efficiency and methane production. This study optimizes the AD system using corn straw and cattle manure as substrates...

  • Article
  • Open Access
12 Citations
2,603 Views
14 Pages

Effect of the N-hexanoyl-L-homoserine Lactone on the Carbon Fixation Capacity of the Algae–Bacteria System

  • Lei Liao,
  • Bin Chen,
  • Kaikai Deng,
  • Qiang He,
  • Guijiao Lin,
  • Jinsong Guo and
  • Peng Yan

Algae–bacteria systems are used widely in wastewater treatment. N-hexanoyl-L-homoserine lactone (AHL) plays an important role in algal-bacteria communication. However, little study has been conducted on the ability of AHLs to regulate algal met...

  • Article
  • Open Access
25 Citations
4,373 Views
12 Pages

27 August 2019

Quorum quenching (QQ) is a promising alternative infection-control strategy to antibiotics that controls quorum-regulated virulence without killing the pathogens. Aeromonas hydrophila is an opportunistic gram-negative pathogen living in freshwater an...

  • Article
  • Open Access
36 Citations
6,161 Views
17 Pages

Antibacterial Activity and Anti-Quorum Sensing Mediated Phenotype in Response to Essential Oil from Melaleuca bracteata Leaves

  • Wenting Wang,
  • Xiaoqin Huang,
  • Huixiang Yang,
  • Xianqian Niu,
  • Dongxiang Li,
  • Chao Yang,
  • Liang Li,
  • Liting Zou,
  • Ziwen Qiu and
  • Shaohua Wu
  • + 1 author

14 November 2019

The prominent antibacterial and quorum sensing (QS) inhibition activity of aromatic plants can be used as a novel intervention strategy for attenuating bacterial pathogenicity. In the present work, a total of 29 chemical components were identified in...

  • Article
  • Open Access
2 Citations
2,920 Views
16 Pages

Design of β-Keto Esters with Antibacterial Activity: Synthesis, In Vitro Evaluation, and Theoretical Assessment of Their Reactivity and Quorum-Sensing Inhibition Capacity

  • Maximiliano Martínez-Cifuentes,
  • Emmanuel Soto-Tapia,
  • Camila Linares-Pipón,
  • Ben Bradshaw,
  • Paulina Valenzuela-Hormazabal,
  • David Ramírez,
  • Patricio Muñoz-Torres and
  • Claudio Parra

22 September 2023

This work proposes the design of β-keto esters as antibacterial compounds. The design was based on the structure of the autoinducer of bacterial quorum sensing, N-(3-oxo-hexanoyl)-l-homoserine lactone (3-oxo-C6-HSL). Eight β-keto ester anal...