Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (73,684)

Search Parameters:
Keywords = Mathematics

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
15 pages, 787 KB  
Article
Chemical Composition and Insecticidal Activity of Essential Oils from Origanum floribundum and Eucalyptus citriodora Against the Louse Bovicola limbatus
by Nassima Chikhi-Chorfi, Fairouz Haddadj, Baya Djellout, Safia Zenia, Mohamed Hazzit, Faiza Marniche, Amel Milla and Amina Smai
Molecules 2025, 30(19), 4001; https://doi.org/10.3390/molecules30194001 - 6 Oct 2025
Abstract
Background: Essential oils, obtained from plants, are an alternative for controlling ectoparasites, particularly lice, mites and ticks, due to the problems posed by chemical insecticides, such as insect resistance, environmental impacts and concerns related to human and animal health. This study aims to [...] Read more.
Background: Essential oils, obtained from plants, are an alternative for controlling ectoparasites, particularly lice, mites and ticks, due to the problems posed by chemical insecticides, such as insect resistance, environmental impacts and concerns related to human and animal health. This study aims to investigate and compare the insecticidal activity of essential oils from Origanum floribundum and Eucalyptus citriodora against the louse Bovicola limbatus. Methods: The chemical composition of the two oils obtained by hydrodistillation was determined by gas chromatography coupled with mass spectrometry (GC-MS) and a flame ionisation detector (FID-MS). To determine insecticidal activity, the essential oils were tested at different concentrations (0.05–0.8 µL/mL), with mortality recorded after 15 min, 30 min, 1 h, 2 h and 4 h of exposure. Results: A corrected mortality rate of 100% was achieved for concentrations of oregano and eucalyptus essential oils of 0.8 µL/mL and 0.4 µL/mL, respectively. The LC50 values were 0.11 and 0.10 µL/mL for oregano and eucalyptus, respectively, after 2 h of treatment. The LC90 values observed are 0.31 and 0.24 µL/mL for oregano and eucalyptus, respectively. Conclusion: Both essential oils have similar and promising insecticidal potential and could be an alternative to chemical insecticides in a control strategy that is more respectful of human and animal health and the environment. Full article
20 pages, 3252 KB  
Article
Multiscale Effects of Land Infrastructure Planning on Housing Prices in Bangkok, Thailand
by Shichao Lu, Zhihua Zhang, M. James C. Crabbe and Prin Suntichaikul
Land 2025, 14(10), 2004; https://doi.org/10.3390/land14102004 - 6 Oct 2025
Abstract
Bangkok is the largest city in Thailand and the second largest city in Southeast Asia. Due to the rapid urbanization and upgrading of economic structures, the real estate market in Bangkok is not only constrained by domestic factors but also fluctuates with international [...] Read more.
Bangkok is the largest city in Thailand and the second largest city in Southeast Asia. Due to the rapid urbanization and upgrading of economic structures, the real estate market in Bangkok is not only constrained by domestic factors but also fluctuates with international economic cycles. Bangkok’s long history, diverse culture, developed economy, and incomplete land infrastructure make the formation of housing prices particularly complex. In this study, we collected 13,175 residence transaction data from 2076 different neighborhoods in Bangkok and explored multiscale effects of various land infrastructure factors on housing prices in Bangkok at the neighborhood level. Our analysis not only supports land planning departments of Bangkok to make more reasonable facility planning but also provides new insights into driving mechanisms of housing prices in other cities of Thailand and ASEAN countries Full article
(This article belongs to the Section Land Use, Impact Assessment and Sustainability)
15 pages, 597 KB  
Article
Developments of Semi-Type-2 Interval Approach with Mathematics and Order Relation: A New Uncertainty Tackling Technique
by Rukhsar Khatun, Sadiah Aljeddani, Shuhrah Alghamdi, Md Sadikur Rahman and Asoke Kumar Bhunia
Axioms 2025, 14(10), 754; https://doi.org/10.3390/axioms14100754 - 6 Oct 2025
Abstract
This paper aims to introduce a new interval approach called the Semi-Type-2 interval to represent imprecise parameters in uncertain decision-making. The proposed work establishes arithmetic operations of Semi-Type-2 intervals with algebraic properties. Additionally, a new interval ranking is proposed in order to compare [...] Read more.
This paper aims to introduce a new interval approach called the Semi-Type-2 interval to represent imprecise parameters in uncertain decision-making. The proposed work establishes arithmetic operations of Semi-Type-2 intervals with algebraic properties. Additionally, a new interval ranking is proposed in order to compare Semi-Type-2 interval numbers, and the corresponding properties of total order relations are also derived. All the definitions and properties related to Semi-Type-2 intervals are illustrated with the help of numerical examples. Numerical illustrations confirm the consistency of the framework and its effectiveness in extending classical interval mathematics. Finally, some probable applications of the Semi-Type-2 interval approach are demonstrated for future implementation. Full article
(This article belongs to the Special Issue Recent Advances in Fuzzy Sets and Related Topics, 2nd Edition)
Show Figures

Figure 1

25 pages, 370 KB  
Article
Lukasiewicz Fuzzy Set Theory Applied to SBE-Algebras
by Tahsin Oner, Hashem Bordbar, Neelamegarajan Rajesh and Akbar Rezaei
Mathematics 2025, 13(19), 3203; https://doi.org/10.3390/math13193203 - 6 Oct 2025
Abstract
In this paper, we utilize the Lukasiewicz t-norm to construct a novel class of fuzzy sets, termed ζ-Lukasiewicz fuzzy sets, derived from a given fuzzy framework. These sets are then applied to the structure of Sheffer stroke BE-algebras (SBE-algebras). We introduce [...] Read more.
In this paper, we utilize the Lukasiewicz t-norm to construct a novel class of fuzzy sets, termed ζ-Lukasiewicz fuzzy sets, derived from a given fuzzy framework. These sets are then applied to the structure of Sheffer stroke BE-algebras (SBE-algebras). We introduce and examine the concepts of ζ-Lukasiewicz fuzzy SBE-subalgebras and ζ-Lukasiewicz fuzzy SBE-ideals, with a focus on their algebraic properties. Furthermore, we define three specific types of subsets, referred to as ∈-sets, q-sets, and O-sets, and investigate the necessary conditions for these subsets to constitute subalgebras or ideals within the SBE-algebraic context. Full article
(This article belongs to the Special Issue Advances in Hypercompositional Algebra and Its Fuzzifications)
29 pages, 2430 KB  
Article
A Federated Fine-Tuning Framework for Large Language Models via Graph Representation Learning and Structural Segmentation
by Yuxin Dong, Ruotong Wang, Guiran Liu, Binrong Zhu, Xiaohan Cheng, Zijun Gao and Pengbin Feng
Mathematics 2025, 13(19), 3201; https://doi.org/10.3390/math13193201 - 6 Oct 2025
Abstract
This paper focuses on the efficient fine-tuning of large language models within the federated learning framework. To address the performance bottlenecks caused by multi-source heterogeneity and structural inconsistency, a structure-aware federated fine-tuning method is proposed. The method incorporates a graph representation module (GRM) [...] Read more.
This paper focuses on the efficient fine-tuning of large language models within the federated learning framework. To address the performance bottlenecks caused by multi-source heterogeneity and structural inconsistency, a structure-aware federated fine-tuning method is proposed. The method incorporates a graph representation module (GRM) to model internal structural relationships within text and employs a segmentation mechanism (SM) to reconstruct and align semantic structures across inputs, thereby enhancing structural robustness and generalization under non-IID (non-Independent and Identically Distributed) settings. During training, the method ensures data locality and integrates structural pruning with gradient encryption (SPGE) strategies to balance privacy preservation and communication efficiency. Compared with representative federated fine-tuning baselines such as FedNLP and FedPrompt, the proposed method achieves consistent accuracy and F1-score improvements across multiple tasks. To evaluate the effectiveness of the proposed method, extensive comparative experiments are conducted across tasks of text classification, named entity recognition, and question answering, using multiple datasets with diverse structures and heterogeneity levels. Experimental results show that the proposed approach significantly outperforms existing federated fine-tuning strategies on most tasks, achieving higher performance while preserving privacy, and demonstrating strong practical applicability and generalization potential. Full article
(This article belongs to the Special Issue Privacy-Preserving Machine Learning in Large Language Models (LLMs))
Show Figures

Figure 1

16 pages, 1112 KB  
Review
The Prognostic Power of miR-21 in Breast Cancer: A Systematic Review and Meta-Analysis
by Luana Conte, Maria Rosaria Tumolo, Giorgio De Nunzio, Ugo De Giorgi, Roberto Guarino, Donato Cascio and Federico Cucci
Int. J. Mol. Sci. 2025, 26(19), 9713; https://doi.org/10.3390/ijms26199713 - 6 Oct 2025
Abstract
Breast cancer (BC) is one of the most common malignancies among women worldwide. Despite advances in early detection and treatment, prognosis remains highly variable. Molecular biomarkers, such as microRNAs (miRNAs), have emerged as promising tools to refine prognostic assessment. Among them, miR-21 is [...] Read more.
Breast cancer (BC) is one of the most common malignancies among women worldwide. Despite advances in early detection and treatment, prognosis remains highly variable. Molecular biomarkers, such as microRNAs (miRNAs), have emerged as promising tools to refine prognostic assessment. Among them, miR-21 is consistently overexpressed in solid tumors and implicated in key oncogenic pathways. This systematic review and meta-analysis aimed to clarify the prognostic significance of miR-21 in BC and explore its molecular mechanisms through bioinformatic analyses. A systematic search of PubMed, Scopus, and Web of Science up to April 2025 identified 18 eligible observational studies. Pooled analyses showed that high miR-21 expression was significantly associated with poorer overall survival (OS) (HR = 2.37, 95% CI: 1.42–3.98) and recurrence-related outcomes (DFS/RFS) (HR = 2.10, 95% CI: 1.32–3.34). Subgroup analyses confirmed robust associations across different cut-off definitions and revealed particularly strong effects in triple-negative BC (HR = 5.69) and mixed subtypes (HR = 2.55), but no significant association in HER2-positive BC. Bioinformatic analysis identified target genes such as PTEN, BCL2, STAT3, and MYC, involved in apoptosis regulation, proliferation, NF-κB signaling, and immune modulation. These findings provide consistent evidence that miR-21 is a promising minimally invasive prognostic biomarker in BC, particularly in aggressive subtypes, and support its integration into future multimodal prognostic models. Full article
(This article belongs to the Special Issue Non-Coding RNA in Physiology and Pathophysiology: Second Edition)
18 pages, 2957 KB  
Article
Modelling a Fuzzy Logic-Based Multiple-Actuator Hydraulic Lifting and Positioning System
by Grzegorz Filo, Edward Lisowski, Paweł Lempa and Konrad Wisowski
Appl. Sci. 2025, 15(19), 10747; https://doi.org/10.3390/app151910747 - 6 Oct 2025
Abstract
This paper presents a fuzzy logic control strategy for synchronising the vertical lifting and positioning of a multi-actuator hydraulic system designed for a 360-ton movable platform. The primary focus is on achieving precise actuator movement coordination under uneven loading conditions without using external [...] Read more.
This paper presents a fuzzy logic control strategy for synchronising the vertical lifting and positioning of a multi-actuator hydraulic system designed for a 360-ton movable platform. The primary focus is on achieving precise actuator movement coordination under uneven loading conditions without using external reference systems or high-cost sensors. A mathematical model and a simulation environment were developed in MATLAB/Simulink with Fuzzy Logic Toolbox. Four fuzzy controller variants were evaluated regarding positioning accuracy, robustness, and compliance with dynamic constraints. The results demonstrate the effectiveness of the proposed control method, particularly when using Gaussian membership functions and PROD–PROBOR fuzzy operators. The system achieved sub-millimetre synchronisation accuracy even under 20% load imbalance. This work contributes to developing decentralised, sensor-light control strategies for large-scale hydraulic systems and offers a validated foundation for future experimental implementation in the PANDA particle detector project. Full article
(This article belongs to the Special Issue Applications of Fuzzy Systems and Fuzzy Decision Making)
Show Figures

Figure 1

17 pages, 2012 KB  
Article
Accurate Measurement of Blast Shock Wave Pressure by Enhanced Sensor System Based on Neural Network
by Fan Yang, Hongzhen Zhu, Deren Kong and Chuanrong Zhao
Sensors 2025, 25(19), 6187; https://doi.org/10.3390/s25196187 - 6 Oct 2025
Abstract
During blast shock wave pressure measurement, strong mechanical vibrations and shocks can affect the dynamic characteristics of shock wave pressure sensors, introducing measurement errors. To improve measurement accuracy for the compression phase, a specialized buffer device was designed to enhance the sensor’s dynamic [...] Read more.
During blast shock wave pressure measurement, strong mechanical vibrations and shocks can affect the dynamic characteristics of shock wave pressure sensors, introducing measurement errors. To improve measurement accuracy for the compression phase, a specialized buffer device was designed to enhance the sensor’s dynamic response to transient pressure rises. Using a double-diaphragm shock tube, the dynamic calibration of the enhanced sensor system was carried out and the influence of the buffer device on the dynamic performance was investigated. A mathematical model based on a backpropagation (BP) neural network was developed to characterize the sensor system, and a dynamic compensation method was implemented to improve the enhanced shock wave pressure sensor system. Experimental results demonstrated that while the buffer device significantly reduced the operational bandwidth of the sensor system, the BP neural network-based dynamic compensation effectively widened the bandwidth and improved measurement accuracy. This research provides a practical solution for high-precision dynamic pressure measurement, specifically targeting the compression phase in complex environments. Full article
(This article belongs to the Section Physical Sensors)
Show Figures

Figure 1

21 pages, 8249 KB  
Article
Short-Term Passenger Flow Forecasting for Rail Transit Inte-Grating Multi-Scale Decomposition and Deep Attention Mechanism
by Youpeng Lu and Jiming Wang
Sustainability 2025, 17(19), 8880; https://doi.org/10.3390/su17198880 - 6 Oct 2025
Abstract
Short-term passenger flow prediction provides critical data-driven support for optimizing resource allocation, guiding passenger mobility, and enhancing risk response capabilities in urban rail transit systems. To further improve prediction accuracy, this study proposes a hybrid SMA-VMD-Informer-BiLSTM prediction model. Addressing the challenge of error [...] Read more.
Short-term passenger flow prediction provides critical data-driven support for optimizing resource allocation, guiding passenger mobility, and enhancing risk response capabilities in urban rail transit systems. To further improve prediction accuracy, this study proposes a hybrid SMA-VMD-Informer-BiLSTM prediction model. Addressing the challenge of error propagation caused by non-stationary components (e.g., noise and abrupt fluctuations) in conventional passenger flow signals, the Variational Mode Decomposition (VMD) method is introduced to decompose raw flow data into multiple intrinsic mode functions (IMFs). A Slime Mould Algorithm (SMA)-based optimization mechanism is designed to adaptively tune VMD parameters, effectively mitigating mode redundancy and information loss. Furthermore, to circumvent error accumulation inherent in serial modeling frameworks, a parallel prediction architecture is developed: the Informer branch captures long-term dependencies through its ProbSparse self-attention mechanism, while the Bidirectional Long Short-Term Memory (BiLSTM) network extracts localized short-term temporal patterns. The outputs of both branches are fused via a fully connected layer, balancing global trend adherence and local fluctuation characterization. Experimental validation using historical entry flow data from Weihouzhuang Station on Xi’an Metro demonstrated the superior performance of the SMA-VMD-Informer-BiLSTM model. Compared to benchmark models (CNN-BiLSTM, CNN-BiGRU, Transformer-LSTM, ARIMA-LSTM), the proposed model achieved reductions of 7.14–53.33% in fmse, 3.81–31.14% in frmse, and 8.87–38.08% in fmae, alongside a 4.11–5.48% improvement in R2. Cross-station validation across multiple Xi’an Metro hubs further confirmed robust spatial generalizability, with prediction errors bounded within fmse: 0.0009–0.01, frmse: 0.0303–0.1, fmae: 0.0196–0.0697, and R2: 0.9011–0.9971. Furthermore, the model demonstrated favorable predictive performance when applied to forecasting passenger inflows at multiple stations in Nanjing and Zhengzhou, showcasing its excellent spatial transferability. By integrating multi-level, multi-scale data processing and adaptive feature extraction mechanisms, the proposed model significantly mitigates error accumulation observed in traditional approaches. These findings collectively indicate its potential as a scientific foundation for refined operational decision-making in urban rail transit management, thereby significantly promoting the sustainable development and long-term stable operation of urban rail transit systems. Full article
Show Figures

Figure 1

13 pages, 2995 KB  
Article
Gluon Condensation as a Unifying Mechanism for Special Spectra of Cosmic Gamma Rays and Low-Momentum Pion Enhancement at the Large Hadron Collider
by Wei Zhu, Jianhong Ruan, Xurong Chen and Yuchen Tang
Symmetry 2025, 17(10), 1664; https://doi.org/10.3390/sym17101664 - 6 Oct 2025
Abstract
Gluons within the proton may accumulate near a critical momentum due to nonlinear QCD effects, leading to a gluon condensation. Surprisingly, the pion distribution predicted by this gluon distribution could answer two puzzles in astronomy and high-energy physics. During ultra-high-energy cosmic ray collisions, [...] Read more.
Gluons within the proton may accumulate near a critical momentum due to nonlinear QCD effects, leading to a gluon condensation. Surprisingly, the pion distribution predicted by this gluon distribution could answer two puzzles in astronomy and high-energy physics. During ultra-high-energy cosmic ray collisions, gluon condensation may abruptly produce a large number of low-momentum pions, whose electromagnetic decays have the typical broken power law. On the other hand, the Large Hadron Collider (LHC) shows weak but recognizable signs of gluon condensation, which had been mistaken for BEC pions. Symmetry is one of the fundamental laws in natural phenomena. Conservation of energy stems from time symmetry, which is one of the most central principles in nature. In this study, we reveal that the connection between the above two apparently unrelated phenomena can be fundamentally explained from the fundamental principle of conservation of energy, highlighting the deep connection and unifying role symmetry plays in physical processes. Full article
(This article belongs to the Section Physics)
Show Figures

Figure 1

29 pages, 5343 KB  
Article
Sound Absorption and Thermal Insulation by Polyurethane Foams Reinforced with Bio-Based Lignocellulosic Fillers: Data and Modeling
by Batol Masruri, Ebrahim Taban, Ali Khavanin and Keith Attenborough
Buildings 2025, 15(19), 3590; https://doi.org/10.3390/buildings15193590 - 5 Oct 2025
Abstract
The acoustic, thermal, and mechanical performances of sawdust-reinforced polyurethane (PU) foam are investigated for different thicknesses and varying mesh sizes. Acoustic properties are explored using a combination of impedance tube testing and mathematical modeling with the Johnson–Champoux–Allard–Lafarge (JCAL) model, a simplified JCAL model [...] Read more.
The acoustic, thermal, and mechanical performances of sawdust-reinforced polyurethane (PU) foam are investigated for different thicknesses and varying mesh sizes. Acoustic properties are explored using a combination of impedance tube testing and mathematical modeling with the Johnson–Champoux–Allard–Lafarge (JCAL) model, a simplified JCAL model and a model of non-uniform cylindrical pores with a log-normal radius distribution (NUPSD). Thermal Insulation and mechanical properties are determined by measuring the effective thermal conductivity (Keff) and by tensile strength tests, respectively. Compared with pure PU foam, the presence of sawdust matches noise reduction coefficients (NRC) and increases sound absorption averages (SAA) by nearly 10%. Increasing thickness and width of backing air gap have the usual effects of improving low- and mid-frequency absorption and shifting resonance peaks toward lower frequencies. As well as superior acoustic performance, samples with Mesh 16 sawdust reinforcement provide both useful insulation (Keff = 0.044 W/mK) and tensile strength (~0.06 MPa), confirming their multifunctionality. Although the JCAL model provides reasonable fits to the sound absorption data, some of the fitted parameter values are unphysical. Predictions of the NUPSD model are relatively poor but improve with sample thickness and after fiber addition. Full article
(This article belongs to the Special Issue Advance in Eco-Friendly Building Materials and Innovative Structures)
Show Figures

Figure 1

20 pages, 1043 KB  
Article
Multi-Criteria Decision-Making Algorithm Selection and Adaptation for Performance Improvement of Two Stroke Marine Diesel Engines
by Hla Gharib and György Kovács
J. Mar. Sci. Eng. 2025, 13(10), 1916; https://doi.org/10.3390/jmse13101916 - 5 Oct 2025
Abstract
Selecting an appropriate Multi-Criteria Decision-Making (MCDM) algorithm for optimizing marine diesel engine operation presents a complex challenge due to the diversity in mathematical formulations, normalization schemes, and trade-off resolutions across methods. This study systematically evaluates fourteen MCDM algorithms, which are grouped into five [...] Read more.
Selecting an appropriate Multi-Criteria Decision-Making (MCDM) algorithm for optimizing marine diesel engine operation presents a complex challenge due to the diversity in mathematical formulations, normalization schemes, and trade-off resolutions across methods. This study systematically evaluates fourteen MCDM algorithms, which are grouped into five primary methodological categories: Scoring-Based, Distance-Based, Pairwise Comparison, Outranking, and Hybrid/Intelligent System-Based methods. The goal is to identify the most suitable algorithm for real-time performance optimization of two stroke marine diesel engines. Using Diesel-RK software, calibrated for marine diesel applications, simulations were performed on a variant of the MAN-B&W-S60-MC-C8-8 engine. A refined five-dimensional parameter space was constructed by systematically varying five key control variables: Start of Injection (SOI), Dwell Time, Fuel Mass Fraction, Fuel Rail Pressure, and Exhaust Valve Timing. A subset of 4454 high-potential alternatives was systematically evaluated according to three equally important criteria: Specific Fuel Consumption (SFC), Nitrogen Oxides (NOx), and Particulate Matter (PM). The MCDM algorithms were evaluated based on ranking consistency and stability. Among them, Proximity Indexed Value (PIV), Integrated Simple Weighted Sum Product (WISP), and TriMetric Fusion (TMF) emerged as the most stable and consistently aligned with the overall consensus. These methods reliably identified optimal engine control strategies with minimal sensitivity to normalization, making them the most suitable candidates for integration into automated marine engine decision-support systems. The results underscore the importance of algorithm selection and provide a rigorous basis for establishing MCDM in emission-constrained maritime environments. This study is the first comprehensive, simulation-based evaluation of fourteen MCDM algorithms applied specifically to the optimization of two stroke marine diesel engines using Diesel-RK software. Full article
(This article belongs to the Special Issue Marine Equipment Intelligent Fault Diagnosis)
Show Figures

Figure 1

24 pages, 3320 KB  
Article
Three-Dimensional Trajectory Tracking for Underactuated Quadrotor-Like Autonomous Underwater Vehicles Subject to Input Saturation
by Chunchun Cheng, Xing Han, Pengfei Xu, Yi Huang, Liwei Kou and Yang Ou
J. Mar. Sci. Eng. 2025, 13(10), 1915; https://doi.org/10.3390/jmse13101915 - 5 Oct 2025
Abstract
This paper focuses on the design of a three-dimensional trajectory tracking controller for underactuated quadrotor-like autonomous underwater vehicles (QAUVs) subject to actuator saturation. A hand position method with a signum function is proposed to handle the under-actuation of QAUVs, while avoiding trajectory tracking [...] Read more.
This paper focuses on the design of a three-dimensional trajectory tracking controller for underactuated quadrotor-like autonomous underwater vehicles (QAUVs) subject to actuator saturation. A hand position method with a signum function is proposed to handle the under-actuation of QAUVs, while avoiding trajectory tracking in the opposite direction. The dynamic surface control (DSC) technique is integrated to eliminates the complexity explosion problem of standard backstepping. An auxiliary dynamic system is employed to handle input saturation. By using Lyapunov stability theory and phase plane analysis, it is proved that the proposed control law ensures that the QAUVs converge to the desired position with arbitrarily small errors, while guaranteeing the uniform ultimate boundedness of the whole closed-loop system. Comparative simulation results verify the effectiveness of the proposed control law. Full article
18 pages, 2231 KB  
Article
An Open, Harmonized Genomic Meta-Database Enabling AI-Based Personalization of Adjuvant Chemotherapy in Early-Stage Non-Small Cell Lung Cancer
by Hojin Moon, Michelle Y. Cheuk, Owen Sun, Katherine Lee, Gyumin Kim, Kaden Kwak, Koeun Kwak and Aaron C. Tam
Appl. Sci. 2025, 15(19), 10733; https://doi.org/10.3390/app151910733 - 5 Oct 2025
Abstract
Background: Personalizing adjuvant chemotherapy (ACT) after curative resection in early-stage NSCLC remains unmet because prior ACT-biomarker findings rarely reproduce across studies. Key barriers are platform and preprocessing heterogeneity, dominant batch effects, and incomplete ACT annotations. As a result, many signatures that perform well [...] Read more.
Background: Personalizing adjuvant chemotherapy (ACT) after curative resection in early-stage NSCLC remains unmet because prior ACT-biomarker findings rarely reproduce across studies. Key barriers are platform and preprocessing heterogeneity, dominant batch effects, and incomplete ACT annotations. As a result, many signatures that perform well in a single cohort fail during external validation. We created an open, harmonized meta-database linking gene expression with curated ACT exposure and survival to enable fair benchmarking and modeling. Methods: A PRISMA-guided search of 999 GEO studies (through January 2025) used LLM-assisted triage of titles, clinical tables, and free text to identify datasets with explicit ACT status and patient-level survival. Eight Affymetrix microarray cohorts (GPL570/GPL96) met eligibility. Raw CEL files underwent robust multi-array average; probes were re-annotated to Entrez IDs and collapsed by median. Covariate-preserving ComBat adjusted platform/study while retaining several clinical factors. Batch structure was quantified by principal-component analysis (PCA) variance, silhouette width, and UMAP. Two quality-control (QC) filters, median M-score deviation and PCA leverage, flagged and removed technical outliers. Results: The final meta-database comprises 1340 patients (223 (16.6%) ACT; 1117 (83.4%) observation), 13,039 intersecting genes, and 594 overall-survival events. Batch-associated variance (PC1 + PC2) decreased from 63.1% to 20.1%, and mean silhouette width shifted from 0.82 to −0.19 post-correction. Seven arrays (0.5%) were excluded by QC. Event depth supports high-dimensional survival and heterogeneity-of-treatment modeling, and the multi-cohort design enables internal–external validation. Conclusions: This first open, rigorously harmonized NSCLC transcriptomic database provides the sample size, demographic diversity, and technical consistency required to benchmark ACT-benefit markers. By making these data openly available, it will accelerate equitable precision-oncology research and enable data-driven treatment decisions in early-stage NSCLC. Full article
Show Figures

Figure 1

14 pages, 11400 KB  
Article
Classification of Blackcurrant Genotypes by Ploidy Levels on Stomata Microscopic Images with Deep Learning: Convolutional Neural Networks and Vision Transformers
by Aleksandra Konopka, Ryszard Kozera, Agnieszka Marasek-Ciołakowska and Aleksandra Machlańska
Appl. Sci. 2025, 15(19), 10735; https://doi.org/10.3390/app151910735 - 5 Oct 2025
Abstract
Plants vary in number of chromosomes (ploidy levels), which can influence morphological traits, including the size and density of stomata cells. Although biologists can detect these differences under a microscope, the process is often time-consuming and tedious. This study aims to automate the [...] Read more.
Plants vary in number of chromosomes (ploidy levels), which can influence morphological traits, including the size and density of stomata cells. Although biologists can detect these differences under a microscope, the process is often time-consuming and tedious. This study aims to automate the classification of blackcurrant (Ribes nigrum L.) ploidy levels—diploid, triploid, and tetraploid—by leveraging deep learning techniques. Convolutional Neural Networks and Vision Transformers are employed to perform microscopic image classification across two distinct blackcurrant datasets. Initial experiments demonstrate that these models can effectively classify ploidy levels when trained and tested on subsets derived from the same dataset. However, the primary challenge lies in proposing a model capable of yielding satisfactory classification results across different datasets ensuring robustness and generalization, which is a critical step toward developing a universal ploidy classification system. In this research, a variety of experiments is performed including application of augmentation technique. Model efficacy is evaluated with standard metrics and its interpretability is ensured through Gradient-weighted Class Activation Mapping visualizations. Finally, future research directions are outlined with application of other advanced state-of-the-art machine learning methods to further refine ploidy level prediction in botanical studies. Full article
Show Figures

Figure 1

Back to TopTop